JP2016536368A5 - - Google Patents

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Publication number
JP2016536368A5
JP2016536368A5 JP2016552435A JP2016552435A JP2016536368A5 JP 2016536368 A5 JP2016536368 A5 JP 2016536368A5 JP 2016552435 A JP2016552435 A JP 2016552435A JP 2016552435 A JP2016552435 A JP 2016552435A JP 2016536368 A5 JP2016536368 A5 JP 2016536368A5
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JP
Japan
Prior art keywords
factor
composition
deficiency
hemophilia
group
Prior art date
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Application number
JP2016552435A
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English (en)
Japanese (ja)
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JP6629744B2 (ja
JP2016536368A (ja
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Priority claimed from PCT/US2014/063676 external-priority patent/WO2015066606A2/en
Publication of JP2016536368A publication Critical patent/JP2016536368A/ja
Publication of JP2016536368A5 publication Critical patent/JP2016536368A5/ja
Application granted granted Critical
Publication of JP6629744B2 publication Critical patent/JP6629744B2/ja
Expired - Fee Related legal-status Critical Current
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JP2016552435A 2013-11-01 2014-11-03 第Xa因子の半減期を延ばす組成物および方法 Expired - Fee Related JP6629744B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361898884P 2013-11-01 2013-11-01
US61/898,884 2013-11-01
US201361918341P 2013-12-19 2013-12-19
US61/918,341 2013-12-19
PCT/US2014/063676 WO2015066606A2 (en) 2013-11-01 2014-11-03 Compositions and methods for increasing the half-life of factor xa

Publications (3)

Publication Number Publication Date
JP2016536368A JP2016536368A (ja) 2016-11-24
JP2016536368A5 true JP2016536368A5 (OSRAM) 2017-12-14
JP6629744B2 JP6629744B2 (ja) 2020-01-15

Family

ID=53005403

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016552435A Expired - Fee Related JP6629744B2 (ja) 2013-11-01 2014-11-03 第Xa因子の半減期を延ばす組成物および方法

Country Status (5)

Country Link
US (1) US20160235824A1 (OSRAM)
EP (1) EP3063170A4 (OSRAM)
JP (1) JP6629744B2 (OSRAM)
CA (1) CA2928762A1 (OSRAM)
WO (1) WO2015066606A2 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150343034A1 (en) * 2013-01-31 2015-12-03 Pfizer Inc. Compositions and methods for counteracting factor xa inhibition
CN105579468A (zh) 2013-09-24 2016-05-11 辉瑞大药厂 包含重组人凝血因子Xa蛋白的异质性群体的组合物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
CA2285705A1 (en) 1997-04-14 1998-10-22 Cor Therapeutics, Inc. Selective factor xa inhibitors
GB9908838D0 (en) * 1998-09-11 1999-06-16 Univ London Fibroblast inhibitor
US6905683B2 (en) * 2000-05-03 2005-06-14 Novo Nordisk Healthcare A/G Human coagulation factor VII variants
MX336958B (es) * 2005-11-15 2016-02-05 Philadelphia Children Hospital Metodos y composiciones para modular la hemostasia.
EP1867660A1 (en) * 2006-06-14 2007-12-19 CSL Behring GmbH Proteolytically cleavable fusion protein comprising a blood coagulation factor
KR102069498B1 (ko) * 2007-09-28 2020-01-23 포톨라 파마슈티컬스, 인코포레이티드 인자 Xa 저해제에 대한 안티도트 및 그것을 사용하는 방법
WO2009061697A1 (en) * 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
US8455439B2 (en) * 2008-11-14 2013-06-04 Portola Pharmaceuticals, Inc. Antidotes for factor Xa inhibitors and methods of using the same in combination with blood coagulating agents
ES2605801T3 (es) * 2009-07-15 2017-03-16 Portola Pharmaceuticals, Inc. Formulación de dosis unitaria de antídoto para inhibidores del factor Xa para su uso en la prevención de la hemorragia
GB2485590A (en) * 2010-11-22 2012-05-23 Univ Ruprecht Karis Heidelberg Method for detecting at least one direct factor Xa inhibitors
US20160015793A1 (en) * 2012-02-16 2016-01-21 Portola Pharmacueticals, Inc. Modulation of factor xa inhibitor mediated blood loss by partial and transient administration of antidote
FR3000895B1 (fr) * 2013-01-11 2017-02-24 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Sa Utilisation d'antidotes d'inhibiteurs de la coagulation indiques dans la prevention ou le traitement de pathologies thromboemboliques
US20150343034A1 (en) * 2013-01-31 2015-12-03 Pfizer Inc. Compositions and methods for counteracting factor xa inhibition

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