JP2016214440A - Kit for mixture injection - Google Patents

Abstract

PROBLEM TO BE SOLVED: To solve problems for example, in a mixture injection work, when a needle of a syringe is pulled out from a vial, a medicine may be scattered in the surrounding.SOLUTION: A bag body 3 comprises a mixture injection work part 13 and a medicine container storage part 15, and the mixture injection work part and the medicine container storage part can be communicated through a plug body which is internally fitted to a communication part 21 and which can penetrate. A needle 49 of a syringe 45 penetrates the plug body of the communication part and a plug body of a vial 59 for sucking a medicine M, and the medicine is dropped in the mixture injection work part 13. The work can be performed by only an operation from outside of the bag body 3, and the medicine is in a sealed space, so that there is no risk of exposure to a worker.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a co-infusion kit used for co-injecting a drug into a drug solution such as an infusion solution.

Conventionally, when a drug is mixedly injected into a drug solution, the drug is sucked from a vial with a syringe and then injected into a medical container filled with the drug solution.
For example, when the container is a bag body, as shown in Patent Document 1, a bag body provided with a chemical solution inlet capable of connecting a syringe is used.

JP 2009-178484 A

In the mixed injection operation, when the syringe needle is pulled out of the vial, the medicine may be scattered around.
Thus, some drugs are dangerous. For example, in the case of an anticancer drug, cytotoxicity and carcinogenicity are recognized, so it is necessary to avoid exposure to the skin as much as possible.
Since it is difficult to completely prevent the occurrence of scattering itself, workers are wearing gowns, gloves, masks, and protective glasses when handling such drugs. There are limits to defense.

  The present invention was made by paying attention to the above-mentioned conventional problems, and provides a novel and useful co-infusion kit that prevents exposure to workers by isolating the scattering space of the drug. For that purpose.

  The present invention has been made to solve the above-mentioned problems, and the invention of claim 1 includes a bag body having a co-infusion operation section, container locking means for attaching and locking a drug container to the bag body, and the drug Supply means for supplying the medicine in the container to the mixed injection working section; and trigger means for actuating the supply means by an operation from outside the bag body; supply of medicine in the medicine container and medicine supply in the supply means The co-infusion kit is characterized in that a mouth is provided in the bag, and the medicine is supplied to the co-infusion section by operating the trigger means.

  The invention of claim 2 is the mixed injection kit according to claim 1, wherein the syringe serves as the drug container, the supply means and the trigger means, and the opening at the tip of the nozzle of the syringe serves as the drug take-out port and the drug supply port. And the medicine is put in the outer cylinder part of the syringe and the gasket is in a retracted state, and the nozzle of the syringe is not attached with a needle and can be removed to close the opening of the tip The co-infusion kit is characterized in that a cap is attached, the nozzle cap is removed and a pusher of the syringe is pushed to supply the medicine from the opening at the tip to the co-infusion section.

The invention of claim 3 is a mixed injection kit according to claim 1, wherein the drug container is made by dividing the bag body by a non-peelable seal part, one side being mixed injection work part and the other sealed with a stopper. Two container parts serving as storage parts, a communication part that penetrates the hardly peelable seal part and communicates the two container parts, and a plug that is attached to the opening of the drug container and seals the communication part A syringe equipped with a needle for supplying the drug in the drug container to the mixed injection working part through the plug of the communicating part and the plug of the communicating part;
The co-infusion kit is characterized in that the syringe is used as a trigger means and the needle as a supply means, the opening of the drug container is a drug take-out port, and the opening at the tip of the needle is a drug supply port.

  According to a fourth aspect of the present invention, in the mixed injection kit according to the third aspect, the outer cylindrical portion of the syringe with the needle is inserted into the mixed injection working portion with the needle side leading, and the outer cylindrical portion is on the edge side of the bag body. It is the kit for mixed injection characterized by being fixed by.

  The invention of claim 5 is the mixed injection kit according to claim 4, wherein the needle tip is surrounded by a cylindrical cover member, and the needle tip is guided toward the communicating portion while covering the needle tip. It is a kit for.

  According to a sixth aspect of the present invention, in the mixed injection kit according to the fifth aspect, one end of the cover member is connected to the communicating portion side, and the outer cylinder portion of the syringe is slidably inserted into the other end side. The mixed injection kit is characterized in that a drug can be dropped from a through hole provided in the cover member.

  The invention according to claim 7 is the mixed injection kit according to claim 6, further comprising a leaf spring member having one end fixed to the cover member and the other end fixed to the outer cylinder portion of the syringe. When the portion advances in the cover member toward the connecting portion, the leaf spring member protrudes outward while being deformed in a U shape, and the periphery of the insertion end portion of the cover member is separated from the inner surface of the bag body. This is a mixed injection kit characterized by the above.

  The invention according to claim 8 is the mixed injection kit according to claim 5, wherein the cover member is formed of an extendable member, and one end side is connected to the connecting portion side or is an opening portion, and the cover The co-infusion kit is characterized in that a needle protrudes due to contraction on the member side and can be pierced, and a drug can be dripped through a through hole or the opening provided in the cover member.

  A ninth aspect of the present invention is the mixed injection kit according to the third aspect, wherein the needle-fixed liquid stop member provided with the easily breakable portion is provided in a state where the needle penetrates the plug of the communicating portion with the drug container. The co-infusion kit is characterized in that the easily breakable portion is used as a trigger means and the liquid stop member with a needle is used as a supply means.

  The invention according to claim 10 is the mixed injection kit according to claim 9, wherein a syringe mounting part is provided in the mixed injection working part, and the medicine can be supplied to the mixed injection working part using a syringe attached thereto. This is a mixed injection kit characterized by

  The invention of claim 11 is a mixed injection kit according to any one of claims 1 to 10 which is used in combination with a sealing clamp, and the bag body has a mixed injection working part extending below the medicine container housing part. A mixed injection kit characterized in that a discharge portion is provided at the lower end of the extended portion and the mixed injection work portion of the bag body can be divided into the discharge portion side and the supply means side by clamping with the sealing clamp It is.

  According to a twelfth aspect of the present invention, in the mixed injection kit according to the eleventh aspect, the bag body is not provided with a suspension hole, and a suspension hole is provided on the hermetic clamp side, and the bag body by the hermetic clamp is provided. This is a co-infusion kit characterized in that a suspension hole is provided on the bag body side by the clamp.

  According to the mixed injection kit of the present invention, since the medicine take-out port and the medicine supply port of the medicine container are provided in the bag, it is possible to isolate the medicine scattering space and prevent exposure to the worker.

It is a perspective view by the side of the bag body of the mixed injection kit which concerns on the 1st Embodiment of this invention. It is the front view and top view of FIG. FIG. 3 is a perspective view of a state in which a connecting portion, a container lock member, and a cover member of FIG. 2 are integrated. FIG. 4 is an exploded perspective view of FIG. 3. FIG. 4 is a cross-sectional view of FIG. 3. It is a front view of the airtight clamp used together with FIG. It is explanatory drawing of the usage method of the mixed injection kit of FIG. It is explanatory drawing of the usage method following FIG. It is explanatory drawing of the usage method following FIG. It is explanatory drawing of the usage method following FIG. It is explanatory drawing of the usage method following FIG. It is explanatory drawing of the usage method following FIG. It is explanatory drawing of the scattering prevention function of a chemical | medical agent. It is the front view which made the cross section the part of the bag body side of the mixed injection kit which concerns on the 2nd Embodiment of this invention. It is explanatory drawing of the usage method of the mixed injection kit of FIG. It is the front view which made the bag body side part of the mixed injection kit which concerns on the 3rd Embodiment of this invention a cross section. It is explanatory drawing of the usage method of the mixed injection kit of FIG. It is the front view which made the bag body side part of the mixed injection kit which concerns on the 4th Embodiment of this invention a cross section. It is explanatory drawing of the usage method of the mixed injection kit of FIG. It is the front view which made a part the bag body side of the mixed injection kit which concerns on the 5th Embodiment of this invention in the cross section. It is explanatory drawing of the usage method of the mixed injection kit of FIG. It is a front view of the kit for mixed injection which concerns on the 6th Embodiment of this invention. It is explanatory drawing of the usage method of the mixed injection kit of FIG.

A mixed injection kit 1 according to a first embodiment of the present invention will be described with reference to the drawings.
As shown in FIGS. 1 and 2, in the mixed injection kit 1, a bag body 3 is used as a container. The bag body 3 has two plastic films 5 cut into the same shape, and is sealed by thermal welding between the edges thereof to form a hard-to-peel edge seal portion 7. The edge seal portion 7 has a missing portion on the right side and the left side, respectively, but the hard seal portions 9 and 55 that are also hardly peelable are formed there by post-processing. The film 5 is flexible, and when pressed from the outside in the above-described sealed state, the shape of the bag body 3 changes without changing the volume.
The film 5 is substantially L-shaped, the right side is a vertically long, substantially rectangular portion, and a substantially square portion is continuously provided on the left side of the upper half. In the vicinity of the boundary between the rectangular portion and the square portion, a hardly peelable hermetic seal portion 11 is vertically cut, and both sides thereof are divided. Of the portions separated by the hermetic seal portion 11, the rectangular portion is the mixed injection working portion 13 and the square portion is the drug container housing portion 15.

The mixed injection working part 13 is a part corresponding to a conventional infusion bag, and a discharge port 17 is attached to the lower end so that the drip tube side can be connected.
Reference numeral 19 denotes an isolation seal portion, which is divided into upper and lower parts across the mixed working portion 13, and an infusion L is filled in the lower portion thereof. Although this isolation seal part 19 is also formed by heat welding, it is easily peelable, and when the lower bag body 3 is pressed strongly and the infusion L is compressed, it peels off and communicates vertically.

The communication member 21 passes through the hermetic seal portion 11 between the mixed injection working portion 13 and the medicine container housing portion 15. The outer surface of the communication member 21 is surrounded and fixed by the hermetic seal portion 11 and the divided state of both container portions is maintained.
As shown in FIG. 3, the communication member 21 has a short cylindrical shape, and as shown in FIG. 4, a step is provided in the middle on the inner surface side, one being a small hole portion 23 and the other being a large hole portion 25. It has become.
A rubber plug 27 that can be pierced is fitted into the communication member 21. The plug body 27 has a two-stage disk shape and corresponds to the inner surface shape of the communication member 21.

  A cylindrical cover member 29 is attached to the small hole portion 23 side of the communication member 21. The cover member 29 has one end in the axial direction fixed to the communication member 21 and connected in a shaft shape, and the outer surfaces thereof are substantially flush. In the cover member 29, a plurality of through holes 31 are formed on the communication member 21 side at regular intervals. The through hole 31 has an oval shape and is elongated in the axial direction. The other end side of the cover member 29 is free, and the free end portion is an insertion port 33. The cover member 29 extends partway in the direction crossing the mixed injection working unit 13.

A container lock member 35 is attached to the large hole portion 25 side of the communication member 21. The container lock member 35 also has one end in the axial direction fixed to the communication member 21 and connected in an axial shape, and their outer surfaces are substantially flush.
As shown in FIG. 3, the container lock member 35 has a circular base portion 37 on the mounting side, and a round communication hole 39 is formed at the center thereof. A plurality of locking pieces 41 rise from the edge of the base portion 37 with a certain interval. Each locking piece 41 is formed in a strip shape and extends in parallel in the axial direction, and a locking claw 43 is formed on the inner surface side of the tip. The locking claw 43 has an arrowhead shape and tapers toward the tip side.
The communication member 21, the cover member 29, and the container lock member 35 are also made of a plastic material.

A syringe 45 is attached to the cover member 29 side.
A needle 49 for co-infusion that can be punctured is attached to the nozzle at the tip of the outer cylinder portion 47 of the syringe 45. A medicine supply port is configured by the opening 49 a at the tip of the needle 49. A gasket 51 is slidably accommodated in the outer cylinder portion 47, and a pusher 53 is attached to the proximal end of the gasket 51.
A syringe 45 is inserted into the mixed injection working part 13 with the needle 49 side at the head using the missing part on the right side of the edge seal part 7 of the bag body 3, and the above-described hermetic seal part 11 and A hermetic seal portion 55 is formed with the same configuration.
The syringe 45 is slidably inserted into the cover member 29 with the nozzle side leading, and the needle 49 is surrounded by the cover member 29. An opening 49 a at the tip of the needle 49 is provided in the bag body 3.

  A leaf spring member 57 is bridged between the cover member 29 and the outer cylinder portion 47 of the syringe 45. The leaf spring member 57 has a rectangular strip shape. As shown in FIG. 2B, one end of the longitudinal direction side is fixed to the cover member 29 and the other end is the opening side of the outer cylinder portion 47. When the bag body 3 is in a flat state, the bag body 3 extends substantially straight along the outer peripheral surface of the outer cylinder portion 47 to the cover member 29. Two leaf spring members 57 are provided, and are opposed to each other with the cover member 29 and the syringe 45 interposed therebetween.

  A vial 59 is attached to the container lock member 35, and the vial 59 is filled with a medicine M. As shown in FIG. 5, a rubber stopper 63 that can be penetrated is fitted into the lid 61 of the vial 59, and this stopper 63 is fitted into an opening 59 a serving as a medicine outlet of the vial 59. Yes. Since a hole is formed in the center of the lid 61, the plug 63 is exposed through the hole. Further, since the lid 61 is a cover type and the opening side of the container body 65 is thin, when the lid 61 is attached, an annular recess 67 is formed between the container body 65 and the side surface of the lid 61. Yes. The vial 59 has the lid 61 side at the top, and a plurality of locking pieces 41 of the container lock member 35 are elastically expanded and inserted into the inside. The vial 59 is locked by being locked by the annular recess 67. An opening 59 a of the vial 59 is provided in the bag body 3.

  The cover member 29, the communication member 21, and the container lock member 35 are connected in an axial shape, and when the needle 49 advances, as shown in FIG. Are penetrated together.

The bag body 3 side is configured as described above, and a hermetic clamp 69 shown in FIG. 6 is used in combination therewith. In the sealing clamp 69, the base ends of the pair of sandwiching pieces 71 and 71 are connected to each other so as to be rotatable. When the flat bag body 3 is sandwiched, a sealing part is formed in the sandwiching portion. become.
There is a portion extending in a semicircular shape outward from an intermediate portion of one clamping piece 71 of the hermetic clamp 69, and a round suspension hole 73 is formed there.

Next, the usage method of this mixed injection kit 1 is demonstrated.
As shown in FIG. 7, the syringe 45 is inserted deeply while pressing the cover member 29 through the film 5 of the bag body 3. Since there is the through hole 31, the outer cylinder portion 47 of the syringe 45 advances smoothly.
During this operation, as shown in FIG. 7A, the film 5 tends to be loosened between the pressed portion and the hermetic seal portion 55, but as shown in FIG. Since the film 57 extends outward while being curved and deformed in a U-shape, the film 5 in the meantime is pressed by the leaf spring member 57 and bulges outward, so that the film 5 is not caught in the insertion port 33.

When inserted to the limit, the needle 49 penetrates both the stopper 27 on the communication member 21 side and the stopper 63 on the vial 59 side.
When the penetration is completed, next, as shown in FIG. 8, the film 5 on the leaf spring member 57 is folded back to the hermetic seal portion 55 side, and the outer cylinder portion 47 of the syringe 45 is being pressed through the folded film 5. Then, after pushing the pusher 53 to advance the gasket 51 and injecting the air in the syringe 45 into the vial 59 through the needle 49 to make a positive pressure, the pusher 53 is pulled and this time, The medicine M is sucked to the syringe 45 side. That is, the medicine M is inserted into the stopper 63 and flows into the outer cylinder portion 47 through the needle 49 that has entered the vial 59 through the opening 59a. Since the scale is displayed on the outer cylinder portion 47 of the syringe 45, the suction amount can be adjusted to the set amount using the scale.
By tilting the bag body 3 or turning it upside down, the needle 49 can be immersed even if the amount of the medicine M in the vial 59 is reduced, so that most can be sucked without waste.

Thereafter, as shown in FIG. 9, the film 5 is stretched while the outer cylindrical portion 47 of the syringe 45 is pulled out from the cover member 29 side to return the bag body 3 to a flat shape. In this state, the opening 49 a at the tip of the needle 49 is directly above the through hole 31 of the cover member 29. In this state, when the pusher 53 is pushed again and the medicine M is taken out from the opening 49 a at the tip, the medicine M is dripped in sequence and accumulates on the isolation seal portion 19.
After all the medicine M has been pushed out, as shown in FIG. 10, the lower part side containing the infusion L is pressed to press the infusion L, and the isolation seal portion 19 is peeled off. Thereby, the mixed injection working unit 13 becomes one, and the medicine M and the infusion L that are supplied dropwise are combined, so that the medicine M and the infusion L are sufficiently mixed by holding the bag body 3.

After that, as shown in FIG. 11, it clamps so that the mixed injection operation part 13 of the bag body 3 may be crossed with the airtight clamp 69, and the mixed injection operation part 13 of the bag body 3 is again divided into two. By this division, the portion containing the mixed liquid of the medicine M and the infusion L on the lower side is sealed, so that it is shielded from the syringe 45 and the like.
And as shown in FIG. 12, when the suspension hole 73 comes to the upper side, the bag body 3 will be in the state folded by the clamping part by the clamping pieces 71 and 71, and the suspension hole 73 will be arrange | positioned on the upper side, It becomes the form similar to the existing infusion bag with the discharge port 17 attached to the lower end. Therefore, it can be handled in the same way as existing ones.

  By clamping with the hermetic clamp 69, the suspension hole 73 is provided on the bag body 3 side, and the suspension to the drip stand becomes possible for the first time, so that forgetting to clamp can be prevented. Further, the bottom side of the pusher 53 of the syringe 45 protrudes from the bag body 3, and a dedicated cap 81 is put on that portion. The cap 81 covers the end of the pusher 53 and is engaged with the flange of the outer cylinder part 47 of the syringe 45 to prevent the pusher 53 from being detached from the outer cylinder part 47 during the drip. Yes. When the pusher 53 is detached from the outer cylinder portion 47, the outside communicates with the inside of the bag body 3 through the outer cylinder portion 47, and the aseptic condition in the bag body 3 is impaired.

The mixed injection is completed through the above series of operations, and the infusion treatment can be performed by using the bag body 3 as an infusion bag as it is.
During this operation, the needle 49 punctures the plug body 63 fitted in the plug body 27 on the side of the communication member 21 and the opening 59a of the vial bottle 59 and inhales the medicine M, and then is pulled out. The medicine M may scatter from the exposed surface on the side where the needle 49 is pulled out at the end of the stopper. As shown in FIG. 13A, due to the configuration of each member, a slight gap is formed between the plug body 63 and the plug body 27, and the surface 64 is exposed. Since the opening 59a is in the bag body 3, the surface 64 is in the sealed medicine container housing 15 and does not leak out. Moreover, since the opening 49a at the tip of the needle 49 is always in the bag body 3, it is possible to completely prevent the medicine M from leaking out.
Further, as shown in FIG. 13B, the surface 28 of the plug 27 is on the side of the sealed co-infusion section 13 and does not leak out.
Further, the cover member 29 guides the advancing / retreating direction of the needle 49 and covers it, so that the needle does not hit the film 5 constituting the bag body 3 to be damaged.

Next, a mixed injection kit 83 according to the second embodiment will be described with reference to FIGS.
The same components as those in the first embodiment are denoted by the same reference numerals, and description thereof is omitted.
As shown in FIG. 14, the bag body 85 has a substantially cross shape. A suspension hole 87 is integrally formed at the top.
Three transparent plastic cylinders 89, 91, 93 are combined so that they can be nested. The middle cylindrical body 91 and the small cylindrical body 93 are respectively provided with convex ridges 92 and 94 projecting outward in an annular shape, and can be inserted into and removed from the outer fitting side cylindrical body by sliding of the portions. Each cylindrical body is formed with a plurality of circumferentially extending through holes 95. The one end side of the large cylindrical body 89 is a communication portion shown in a sectional view, and is closed by a rubber plug 97. Further, a cover portion is constituted by a portion extending to the other end side of the large cylindrical body 89 and the two cylindrical bodies 91 and 93.

Further, one end side of the large cylindrical body 89 is formed in a tapered shape. This taper portion can be expanded elastically, and the taper portion serves as a locking edge portion 99 to constitute a container lock portion.
The nozzle side of the outer cylindrical portion 47 of the syringe 45 is shallowly inserted into and fixed to a small cylindrical portion 93. Further, the lid 61 of the vial 59 is inserted into the locking edge 99 and locked.
As shown in FIG. 15, when the outer cylinder portion 47 of the syringe 45 is moved toward the vial 59 while being pressed through the films 5 and 5 of the bag body 3, the cylindrical bodies 89, 91, and 93 are stored in a nested manner. Then, the syringe 45 shrinks and the syringe 45 approaches the vial 59, so that the mixed injection operation can be performed as in the first embodiment.
In addition, since the suspension hole 87 is integrally formed in this bag body 3, a simple thing without a conventional suspension hole can be used as a sealing clamp. It cannot serve as a reminder to forget to clamp, but there is an economic advantage if a simple one can provide a low unit price.

Next, a mixed injection kit 101 according to a third embodiment will be described with reference to FIGS.
The same components as those in the first and second embodiments are denoted by the same reference numerals, and description thereof is omitted.
As shown in FIG. 16, the cover member 103 is made of a flexible tube made of silicon. One end side of the cover member 103 is attached to the nozzle of the outer cylinder portion 47 of the syringe 45 and surrounds the needle 49. The other end side is a free end and extends beyond the tip of the needle 49 to the far end.
The vial 59 is attached to the connecting member 105. An annular ridge 107 is formed in the middle of the inner surface of the connecting member 105 (shown in the sectional view). A rubber plug 109 is fitted in such a way as to contact the ridge 107, and an annular contact member 111 is inserted between which an edge of the plug 109 is sandwiched. The abutting member 111 is fixed to the connecting member 105 so that the plug 109 cannot be pulled out.

  Reference numeral 113 denotes a fixing member. The fixing member 113 has a cylindrical shape, and flanges project inwardly on both ends in the axial direction. The connecting member 105 is fitted inside, and is pressed by the flange from both ends in the axial direction. The flange on the one end side is a locking edge 115 of the vial 59, and the mouth is widened outwardly so as to be easily inserted. Since the fixing member 113 is elastically bent, the locking edge 115 can be elastically expanded to form a container lock portion. Accordingly, the vial 59 can be locked as shown. The above-described members are assembled and integrated into a unit product 117.

  As shown in FIG. 17, when the outer cylinder portion 47 of the syringe 45 is moved toward the vial 59 while being pressed through the films 5 and 5 of the bag body 3, the cover member 103 is contracted into a bellows shape. Since 45 is close to the vial 59, the mixed injection operation can be performed as in the first embodiment. Further, since the cover member 103 is not connected to the communication part side, the medicine M sucked into the syringe 45 can be dropped into the mixed injection working part 13 from the front end opening of the cover member 103.

Next, a mixed injection kit 119 according to a fourth embodiment will be described with reference to FIGS.
The same components as those in the first embodiment are denoted by the same reference numerals, and description thereof is omitted.
As shown in FIG. 18, the bag body 121 has a vertically long rectangular shape as a whole, the upper left half is occupied by the medicine container housing portion 15, and the mixed injection working portion 13 occupies the right half and the entire lower portion.
In addition, the syringe 45 is attached in a state where the attachment portion 123 penetrates the hermetic seal portion 55 of the bag body 121 so that the syringe 45 can be attached immediately before the mixed injection operation. The mounting portion 123 is obtained by removing the fixing member 113 from the unit product 117.

As shown in FIG. 19, when the syringe 45 is attached, the needle 49 penetrates through the plug 63 fitted in the opening 59 a of the vial 59. When the syringe 45 is removed, the needle 49 is pulled out from the vial 59, so that the inhaled medicine M can be dropped into the mixed injection working unit 13 from the opening 49a at the tip in the bag body 121.
The plug on the mounting portion 123 side is exposed on the side where the needle 49 is withdrawn. However, since the hermetic seal portion 55 is retracted from the edge, the drug M from the exposed portion is also removed when the needle 49 is withdrawn therefrom. Can be suppressed as much as possible. Since the bag body side can be easily manufactured by attaching the syringe 45 to the rear, such a configuration can be considered in view of cost.

Next, a mixed injection kit 125 according to a fifth embodiment will be described with reference to FIGS.
The same components as those in the fourth embodiment are denoted by the same reference numerals, and description thereof is omitted.
A rubber stopper 127 is fitted in the fixing member 113. A flange pull pin 129 is used as a liquid stopper member with a needle, and the flange pull pin 129 passes through the plug 63 fitted in the opening 59a. The easily breakable portion 133 that the needle 131 penetrates the stopper 63 of the vial 59 and is easily broken is disposed in the mixed injection working portion 13. The flange pull pin 129 serves as a supply unit and a trigger unit.
Further, two mounting portions 135 are mounted on the upper and lower sides through the right edge seal portion 7 of the mixed injection working unit 13. The mounting portion 135 is different in shape from the mounting portion 123 but has the same function.

As shown in FIG. 21, when the easily breakable portion 133 of the flange pull pin 129 is bent from the outside of the bag body 121 through the film 5 and opened, a medicine supply port 129a is formed, and this medicine supply port 129a is formed. The drug M can be dripped from.
Moreover, the prefilled type syringe 45 can be attached and the medicine M previously filled therein can be dropped.
Since the medicine M is expensive, the vial 59 is filled with a minimum amount of the medicine M and is additionally supplied on the syringe side, so that the medicine M is not wasted.
Two mounting portions are provided, and even when two are used due to the volume of the syringe, scattering of the medicine M can be suppressed by using a different mounting portion each time.

In the fourth and fifth embodiments, the stopper through which the syringe 45 penetrates is not held in the sealed space, but the stopper 63 on the vial 59 side is held in the sealed space. That alone significantly reduces the risk of worker exposure.
Further, if the syringe 45 can be reduced in size, it is possible to move to the drip treatment without pulling out, in which case the risk of exposure as described above is eliminated.

Next, a mixed injection kit 141 according to a sixth embodiment will be described with reference to FIGS.
The bag body 142 includes two plastic films 143 cut in the same shape, and is sealed by thermal welding between the edges thereof to form a hard-to-peel edge seal portion 7. Although the edge seal portion 7 has a missing portion on the right side, a hardly peelable hermetic seal portion 55 is formed by post-processing. The film 143 is flexible, and when pressed from the outside in a sealed state, the shape of the bag body 142 changes without changing the volume.
The film 143 has a substantially rectangular shape, and this rectangular portion serves as a mixed injection working part 139.

The discharge port 17 is attached to the lower end of the mixed injection working part 139 so that the drip tube side can be connected.
Reference numeral 19 denotes an isolation seal part, which is divided into upper and lower parts across the mixed working part 139, and the lower part thereof is filled with an infusion L. Although this isolation seal part 19 is also formed by heat welding, it is easy to peel off, and when the lower bag body 142 is pressed strongly and the infusion L is compressed, it peels and communicates vertically.

A syringe 145 is attached to the bag body 142. The syringe 145 is a prefilled syringe in which a medicine is put. That is, the heat-resistant medicine M is placed in the outer cylinder portion 47 of the syringe 145, and the slidable gasket 51 is retracted. A pusher 53 is attached to the proximal end of the gasket 51. In addition, the nozzle 144 is attached with a removable nozzle cap 146 that is not attached with a needle, and closes the opening 144 a at the tip of the nozzle 144.
The syringe 145 is inserted into the mixed injection working part 139 using the missing part of the edge seal part 7 of the bag body 142 with the nozzle cap 146 side as the head, and the hermetic seal part 55 is later formed in this missing part. Yes.
In the present embodiment, the syringe 145 serves as the medicine container, the supply means, and the trigger means. Further, the opening 144a serves as a medicine take-out port and a medicine supply port.

Next, a method for using the mixed injection kit 141 will be described.
The nozzle cap 146 is gripped through the film 143 and pulled strongly to remove it from the nozzle 144. Then, the pusher 53 is pushed to advance the gasket 51 to a desired scale so that a predetermined amount of the medicine M flows out from the opening 144a at the tip of the nozzle 144 to the co-injection working unit 139. The subsequent usage is the same as in the above-described embodiment.
In this mixed injection kit 141, the syringe 145 containing the medicine M is attached to the bag body 142, and then heat sterilization is performed.

The embodiment of the present invention has been described in detail above. However, the specific configuration is not limited to this embodiment, and the present invention can be changed even if there is a design change without departing from the gist of the present invention. included.
For example, it is also conceivable to put a powdery medicine in a vial, inject the liquid that has been placed on the syringe side into the vial, and re-inhale the powdered medicine dissolved in this liquid into the syringe. .
It is also conceivable to attach the vial bottle at a site such as a hospital and then close the mouth with a hermetic clamp, heat seal or the like to seal the container housing.
In the above embodiment, when a mixture injection kit in which air is not sealed in the syringe (the pusher is advanced), the pusher is retracted during use to suck the air in the mixed injection working portion into the syringe. However, the present invention is not limited to this, and it is also possible to manufacture a co-infusion kit in which air is sealed in advance (with the pusher retracted) in a syringe.

1 ... Mixed injection kit (first embodiment)
DESCRIPTION OF SYMBOLS 3 ... Bag body 5 ... Film 7 ... Edge seal part 9, 11, 55 ... Sealing seal part 13 ... Mixed injection work part 15 ... Drug container accommodating part 17 ... Discharge port 19 ... Isolation seal part 21 ... Communication member 27 ... Plug body 29 ... Cover member 35 ... Container locking member 45 ... Syringe 59 ... Vial bottle 59a ... Opening of vial bottle 63 ... Plug body 49 ... Needle 69 ... Sealing clamp 73 ... Suspension hole 83 ... Mixed injection kit (second embodiment)
85 ... Bag body 89, 91, 93 ... Cylindrical body 101 ... Mixed injection kit (third embodiment)
103 ... Cover member 117 ... Unit product 119 ... Mixed injection kit (fourth embodiment)
123... Mounting part 125 .. mixed injection kit (fifth embodiment)
129 ... Flange pull pin 129a ... Flange pull pin drug supply port 135 ... Syringe mounting portion 141 ... Mixed injection kit (sixth embodiment)
DESCRIPTION OF SYMBOLS 139 ... Mixed injection work part 142 ... Bag body 143 ... Film 144 ... Nozzle 144a ... Opening of the tip of a nozzle 145 ... Syringe 146 ... Nozzle cap L ... Infusion solution M ... Drug

Claims (12)

A bag body having a mixed injection working section; container locking means for attaching and locking a medicine container to the bag body; supply means for supplying the medicine in the medicine container to the mixed injection working section; and Equipped with trigger means to be activated by operation from outside,
A co-infusion kit, wherein a medicine take-out port of the medicine container and a medicine supply port of the supply means are provided in the bag, and the medicine is supplied to the co-infusion operation section by operation of the trigger means. In the mixed injection kit according to claim 1,
The syringe also serves as a medicine container, supply means, and trigger means, the opening at the tip of the nozzle of the syringe also serves as a medicine take-out port and a medicine supply port, and the gasket is retracted because the medicine is placed in the outer cylinder portion of the syringe. The nozzle of the syringe is not attached with a needle and can be removed and a nozzle cap that closes the opening of the tip is attached, and the nozzle cap is removed and the syringe pusher is pushed. A mixed injection kit, wherein the medicine is supplied from the opening at the tip to a mixed injection working unit. In the mixed injection kit according to claim 1,
Made by dividing the bag body with a hard-to-removable seal part, penetrating through the two container parts, one of which is a mixed injection working part and the other of which is a container for a medicine container sealed with a stopper, and the hard-to-removable seal part A communication part for communicating the two container parts; a plug that is attached to the opening of the drug container and seals the communication part;
A syringe equipped with a needle for supplying the medicine in the medicine container to the mixed injection working part through the medicine container and the piercing plug of the communicating part;
A co-infusion kit using the syringe as a trigger means and the needle as a supply means, wherein the opening of the drug container is a drug take-out port, and the opening at the tip of the needle is a drug supply port. In the mixed injection kit according to claim 3,
A mixed injection kit characterized in that an outer cylinder portion of a syringe with a needle is inserted into a mixed injection operation portion with a needle side as a head, and the outer cylinder portion is fixed on an edge side of the bag body. In the mixed injection kit according to claim 4,
A mixed injection kit characterized in that the needle tip is surrounded by a cylindrical cover member and is guided toward the communicating portion while covering the needle tip. In the mixed injection kit according to claim 5,
One end side of the cover member is connected to the communicating portion side, and the outer cylinder portion of the syringe is slidably inserted into the other end side, so that the drug can be dropped from the through hole provided in the cover member. A mixed injection kit characterized by In the mixed injection kit according to claim 6,
A leaf spring member having one end fixed to the cover member and the other end fixed to the outer cylinder portion of the syringe is provided,
When the outer cylinder portion advances in the cover member toward the connecting portion, the leaf spring member projects outward while being deformed in a U shape, and the periphery of the insertion end portion of the cover member extends around the inner surface of the bag body. Kit for mixed injection characterized by being separated from the body. In the mixed injection kit according to claim 5,
The cover member is composed of a member that can be expanded and contracted, and one end side is connected to the connection portion side or is an opening, and the needle protrudes due to the shrinkage on the cover member side, and can be pierced. A co-infusion kit, characterized in that a drug can be dropped through a through hole provided in the opening or the opening. In the mixed injection kit according to claim 3,
A liquid stop member with a needle provided with an easily breakable part is provided in a state in which the needle penetrates the plug of the communicating part with the drug container,
A kit for co-infusion using the easily breakable portion as a trigger means and the liquid stop member with a needle as a supply means. In the mixed injection kit according to claim 9,
A mixed injection kit characterized in that a syringe mounting portion is provided in the mixed injection working portion, and a medicine can be supplied to the mixed injection working portion using a syringe attached thereto. The mixed injection kit according to any one of claims 1 to 10 is used in combination with a sealing clamp,
In the bag body, the mixed injection working part extends below the medicine container housing part, and a discharge part is provided at the lower end of the extension part,
A mixed injection kit characterized in that the mixed injection work part of the bag body can be divided into the discharge part side and the supply means side by a clamp by the sealing clamp. In the mixed injection kit according to claim 11,
There is no suspension hole in the bag body, a suspension hole is provided on the sealing clamp side,
A co-infusion kit comprising a suspension hole on the bag body side by clamping the bag body with the hermetic clamp.

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