JP2016140527A - Powder dispensing container - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a powder dispensing container in which a dispensing preparation operation is simple and proper quantitative powder can always be dispensed stably.SOLUTION: A powder dispensing container is formed by combining an air pressure feed mechanism 40 for pumping air, a fixed plug 30 engaged with the air pressure feed mechanism 40, and cartridge 2 with a syringe part 12 for receiving powder P. The cartridge 2 includes a recess 12a recessed in a predetermined height range of an inner circumferential surface of the syringe part 12, and an inside plug 20 installed in the inside of the syringe part 12. The powder dispensing container is characterized in that the inside plug 20 is pushed up by a projection 35 of the fixed plug 30 when the cartridge 2 is combined with the fixed plug 30, and an air flow path is formed for ejecting the powder P received in the inside of the syringe part 12 to the outside using the air pumped by the air pressure feed mechanism 40.SELECTED DRAWING: Figure 2

Description

  The present invention relates to a powder administration container for administering a powdered drug to the nostril, nasal cavity or oral cavity and absorbing it through the nasal mucosa or oral mucosa.

  For patients with diseases such as rhinitis and nasal allergies, dedicated medication containers are used in which drug powder sealed in a cartridge is sprayed into the nostril / nasal cavity for administration. As a conventional medication container, a storage chamber for storing a powdered medicine is disposed between a medicine ejection nozzle and an air pump for supplying air to the storage room, and the air is pressed into the storage chamber by pressing the air pump. There is known a structure in which a medicine is ejected from a nozzle hole by press-fitting (see, for example, Patent Document 1).

  However, in the dosing container described in Patent Document 1, since it is necessary to open the mouth of the air pump by moving the inner plug by air pressure, a large amount of drug powder is generated at the initial stage of ejection when the air pump mouth is opened. On the other hand, if the pressure of the air pump is too weak to fear the large amount of drug powder, the movement of the inner plug will not be stable, and the spray of drug powder will become unstable and stable administration. It was difficult to control. Further, in Patent Document 1, when a cartridge for storing drug powder is attached to an air pump, the cartridge must be inverted upside down to remove the bottom lid, and the cartridge must be attached to the air pump in an inverted state. It takes time to prepare for administration.

JP 2011-15954 A

  An object of the present invention is to solve the above-mentioned problems, and to provide a powder dosing container in which an administration preparation operation is simple and an appropriate amount of powder can always be stably administered.

As a means for solving the above problems, the powder administration container according to the present invention is:
Combining a pneumatic feeding mechanism that pumps air, a fixing plug that engages with the pneumatic feeding mechanism, and a cartridge that includes a syringe part that stores powder,
The cartridge includes a concave portion recessed in a predetermined height range of the inner peripheral surface of the syringe portion, and an inner stopper installed inside the syringe portion,
When the cartridge and the stopper plug are combined, the inner stopper is pushed up by the protruding portion of the stopper stopper, and the powder contained in the syringe part is ejected to the outside by the air fed by the pneumatic feeding mechanism. An air flow path is formed.

  In this configuration, the inner plug is pushed up by the protruding portion of the fixed plug, thereby forming an air flow path for injecting the powder to the outside inside the syringe portion. Therefore, an appropriate amount of powder is always stably administered. It is possible. In addition, preparation operations for administration such as a combination of cartridges can be easily performed.

  A communication hole is formed in the inner plug side wall of the inner plug.

  Moreover, the outer peripheral diameter of the inner plug side wall of the inner plug is smaller than the inner peripheral diameter of the syringe part, and a gap is formed over the entire circumference between the inner plug side wall and the syringe part, and the inner peripheral surface of the syringe part The recesses are provided intermittently at intervals in the circumferential direction.

  Moreover, the shape of the upper surface of the inner plug is a conical shape or a truncated cone.

  Further, the pneumatic feeding mechanism is a squeezable deformable and reversible flexible bottle.

  The pneumatic feeding mechanism is a syringe having a movable pusher.

The above-described configuration of the present invention has the following effects.
In the present invention, the inner plug is pushed up by the protruding portion of the fixed plug, thereby forming an air flow path for injecting the powder to the outside inside the syringe portion. Therefore, an appropriate amount of powder is always stably administered. Is achieved. In addition, preparation operations for administration such as a combination of cartridges can be easily performed.

  Further, in the present invention, since the communication hole is perforated on the inner plug side wall of the inner plug, it is achieved that the air flow path to be ejected to the outside by communicating with the recess is reliably formed.

  In the present invention, the outer diameter of the inner plug side wall of the inner plug is smaller than the inner diameter of the syringe part, and a gap is formed between the inner plug side wall and the syringe part over the entire circumference. Since the concave portions are intermittently provided in the circumferential surface at intervals in the circumferential direction, it is possible to suppress the inner plug side wall from being inclined and blocking the air flow path.

  In the present invention, since the upper surface of the inner plug has a conical shape or a truncated cone, it is possible to efficiently guide the powder together with the pressure-fed air to the ejection port.

  Further, according to the present invention, the pneumatic feeding mechanism can easily perform air pressure feeding in a squeezable deformable and reversible flexible bottle or a syringe having a movable pusher.

It is a longitudinal cross-sectional view in 1st Embodiment of the powder administration container which concerns on this invention. It is a longitudinal cross-sectional view when ejecting powder in the first embodiment. It is a longitudinal cross-sectional view in 2nd Embodiment of the powder administration container based on this invention. It is a longitudinal cross-sectional view when ejecting powder in the second embodiment. It is a longitudinal cross-sectional view in 3rd Embodiment of the powder administration container based on this invention. It is a longitudinal cross-sectional view when ejecting powder in the third embodiment.

  Embodiments of the present invention will be described below with reference to the drawings.

  FIG. 1 is a longitudinal sectional view of each member of the cartridge 2, the cap 50, the fixing plug 30, and the pneumatic feeding mechanism 40 in the first embodiment of the powder administration container according to the present invention, and FIG. 2 shows the first embodiment. It is a longitudinal cross-sectional view when the powder P is ejected in the form.

  The powder dosing container 1 according to the first embodiment includes a cartridge 2 containing the powder P, a cap 50 fitted to the upper part of the cartridge 2, and a pneumatic feed that pumps air to eject the powder P. A mechanism 40 and a fixing plug 30 for combining the pneumatic feeding mechanism 40 with the cartridge 2 are configured. The cartridge 2 includes a nozzle body 10 and an inner plug 20 installed inside the nozzle body 10. Examples of the powder P include drugs administered from the nostril / nasal cavity and oral cavity.

  The nozzle body 10 has a nozzle 11 for delivering the powder P to a target nostril / nasal cavity or oral cavity, and a syringe part 12 formed of a cylindrical space for storing the powder P therein is provided below the nozzle 11. Provided. In the predetermined height range of the inner peripheral surface of the syringe part 12, a recess 12a that is recessed over the entire periphery is provided. In addition, you may provide the recessed part 12a intermittently at intervals in the circumferential direction. A nozzle 13 for ejecting the powder P is drilled at the tip of the nozzle 11. An outer peripheral wall 12b is provided around the syringe part 12 in the form of an outer casing and is suspended from the outer end part to have a double structure. The outer peripheral wall 12b is formed in a flat plate shape formed in an axially symmetric position. A pair of blade portions 14, 14 is formed. A pair of projecting pieces 15 formed at positions that are axially symmetrical outward from the lower end of the outer peripheral wall 12b are disposed below the blades 14 and screwed into female threaded ridges 33 described later. It is supposed to be. The lowermost end portion of the syringe portion 12 is covered with a seal 16 at the lowermost end portion so as to prevent moisture absorption of the powder P and prevent foreign matter from entering the syringe portion. When the seal 16 is peeled off with a finger, a knob portion may be provided on the seal 16.

  The shape of the nozzle 11 includes a truncated cone shape having a wide downstream end width and a narrow upstream end width, a cylindrical shape having a uniform width such as a cube, and a shape in which the downstream end portion becomes wider in this uniform width shape. Can be mentioned.

  The inner plug 20 installed in the syringe part 12 has a cylindrical inner plug side wall 21 having an outer peripheral diameter substantially the same as the inner peripheral diameter of the syringe part 12, and the inner plug side wall 21 has a plurality of communication holes. A hole 22 is drilled. The bottom portion of the inner plug 20 has a projecting portion that bulges downward, and the bottom surface of the projecting portion is a flat surface in contact with the projecting portion 35 described later, while the upper surface is powdered together with the air that has been pumped. In order to efficiently guide P to the ejection port 13, a conical shape or a truncated cone shape is preferable.

  The fixing plug 30 is provided with an outer peripheral wall 31 that fits and connects the cartridge 2 and the pneumatic feeding mechanism 40, and a locking projection 31 b that engages with the pneumatic feeding mechanism 40 protrudes from a lower inner peripheral surface of the outer peripheral wall 31. On the upper inner peripheral surface of the outer peripheral wall 31, a female threaded ridge 33 is provided so that the projecting piece 15 is screwed. A flange-shaped top plate 31a is projected radially inward from the intermediate portion of the fixing plug 30, and engages with the inside of the opening cylinder portion 43 of the pneumatic feeding mechanism 40 from the top plate 31a. An inner peripheral wall 32 hanging down for sealing is provided, and an inner nozzle 34 is erected from the inner end of the top plate 31a. In the center of the inner nozzle 34, a protruding portion 35 that is held by a plurality of beams (not shown) extending from the inner wall of the inner nozzle 34 is erected.

  The pneumatic feeding mechanism 40 shown in FIG. 1 and FIG. 2 is a squeeze deformable and reversible flexible bottle 41 formed of a synthetic resin having elasticity such as polyethylene or polypropylene by blow injection molding or the like. is there. The body portion of the bottle 41 can be squeezed (pressed), and the air inside can be pumped from the opening cylinder portion 43.

Next, the usage method of the powder administration container 1 is demonstrated.
The cartridge 2 in FIG. 1 has a powder P stored in a syringe portion 12 formed of a cylindrical space, and a cap 50 is fitted to the upper portion of the cartridge 2 in order to prevent the powder P from being altered by moisture absorption. And the inside of the whole lower end of the syringe part 12 is kept airtight by a seal 16.

  In order to assemble the cartridge 2 that is kept airtight in this manner to the fixing plug 30 engaged with the bottle 41 shown in FIG. 2, alignment is performed so that the outer periphery of the syringe portion 12 is accommodated in the inner periphery of the inner nozzle 34. After the inner nozzle 34 is inserted between the syringe part 12 and the outer peripheral wall 12b, the cartridge 2 is pushed down, and then the blades 14 and 14 are pushed by hand to turn the cartridge 2 to rotate the protruding piece 15 And the female thread protrusion 33 are screwed together. As the rotational screwing proceeds, the cartridge 2 is pushed down, and the protrusion 35 pushes up the inner plug 20. When reaching the position where the protrusion 15 and the female thread protrusion 33 are screwed together, the communication hole 22 of the inner plug 20 reaches the recess 12a of the syringe part 12, and the communication hole 22 and the recess 12a communicate with each other. An air flow path is formed in the syringe part 12 as indicated by the broken arrow in the figure.

Then, after removing the cap 50 at the top of the cartridge 2 and holding the powder administration container 1 with a nostril or oral cavity and squeezing (pressing) the body of the bottle 41, the air inside the bottle 41 is communicated with the communication hole 22. The powder P is pumped from between the recess 12a and the upper part of the inner plug side wall 21 through the air flow path communicating with the recess 12a. Spouted outside.
The seal 16 covering the entire circumference of the lowermost end of the syringe part 12 may be peeled off when the cartridge 2 is assembled to the fixing plug 30 or may be broken by the protruding part 35 without being peeled off.

  When the nozzle 11 is inserted into the nasal cavity, the oral cavity, or the like, the pair of blade parts 14 abut against the edge of the nasal cavity or the edge of the oral cavity, and the nozzle 11 further enters the nasal cavity or oral cavity. Therefore, the safety as a powder administration container can be improved.

  3 and 4 show the second embodiment, and the difference between the inner plug 20 shown in the second embodiment and the inner plug 20 of the first embodiment is the configuration of the inner plug side wall 21. The communication hole 22 is not formed, and the concave portion 12a on the inner peripheral surface of the syringe portion 12 is provided intermittently at intervals in the circumferential direction. The other configuration is the same as that of the first embodiment. It is the same.

  As shown in FIGS. 3 and 4, the inner stopper side wall 21 in the second embodiment is cylindrical, whereas the inner stopper side wall 21 in the first embodiment is in contact with the inner periphery of the syringe portion 12. The outer peripheral diameter of the inner stopper side wall 21 is smaller than the inner peripheral diameter of the syringe part 12, and a gap 23 is formed between the inner stopper side wall 21 and the syringe part 12 over the entire circumference. The recess 12a is provided intermittently at intervals in the circumferential direction, which can prevent the inner plug side wall 21 from being inclined and blocking the air flow path. The inner plug 20 is assembled to the lowermost end portion of the syringe portion 12 via a flange-shaped base portion 24 extending outward from the lowermost end portion of the inner plug side wall 21. Therefore, at the time of assembling the cartridge 2, when the inner stopper 20 is set, the set positioning is possible by the flange-like base portion 24 hitting the lowermost end portion of the syringe portion 12.

  When in use, as in the first embodiment, after aligning the outer periphery of the syringe part 12 within the inner periphery of the inner nozzle 34, the cartridge 2 is pushed down, and then the blade parts 14, 14 are moved by hand. When the cartridge 2 is rotated by being pushed around, the inner plug 20 starts to be pushed up by the projecting portion 35 and is broken along the weakened portion provided at the connecting portion between the base 24 and the inner plug side wall 21. Then, a gap 23 is formed between the inner plug side wall 21 and the syringe part 12 over the entire circumference, and when reaching the position where the protrusion 15 and the female screw protrusion 33 are screwed together, the recess 12a and the gap 23 communicate with each other. The passage of air is improved, and the powder P accommodated inside the syringe part 12 is jetted to the outside from the jet port 13 by the pressure-fed air passing through the air flow path indicated by the broken arrow in the figure.

  5 and 6 show the third embodiment. The pneumatic feeding mechanism 40 and the gap 51 shown in the third embodiment are different from the first embodiment, and other configurations are as follows. This is the same as in the first embodiment.

  As shown in FIGS. 5 and 6, the pneumatic feeding mechanism 40 in the third embodiment is a syringe 42 having a movable pusher 44. A slit 51 is suspended from the upper part of the jet nozzle 13 and is molded integrally with the cartridge 2.

  In the third embodiment, the cartridge 2 is assembled to the fixed stopper 30 engaged with the syringe 42 to form an air flow path inside the syringe portion 12, and then the tear-off ejection port 13 is opened even if the tear-off portion 51 is rotated. Then, air is pumped by pushing the pusher 44 of the syringe 42 upward, and the powder P stored in the syringe part 12 is ejected from the ejection port 13 to the outside.

  In the above embodiment, the screwing of the projecting piece 15 and the female threaded ridge 33 has been described as a form in which the cartridge 2 is engaged with the fixing plug 30, but the present invention is not limited to this, and the upper side of the outer peripheral wall 31. A groove is formed in an L-shape or an inverted T-shape composed of a longitudinal groove extending in the vertical direction of the inner circumference and a transverse groove extending in the circumferential direction at the lower end of the longitudinal groove. The projecting piece 15 may be pushed down along and then engaged by sliding the projecting piece 15 into the lateral groove at the lower end.

Moreover, although the said embodiment showed and demonstrated the case where a pair of blade | wing part 14 was provided in the position used as the axial symmetry of the outer wall of the syringe part 12 which comprises the cartridge 2, the formation position in the blade | wing part 14 is axisymmetric. The number of blades 14 is not limited to a pair (two).
Further, the pneumatic feeding device may have any structure as long as it can feed air into the cartridge, such as a bellows container. Furthermore, it can also be set as the structure which provided the pneumatic feeder and the fixed stopper integrally.

  As described above, the powder administration container of the present invention has a simple administration preparation operation and can stably administer an appropriate amount of powder at all times. This can be achieved over a wide area.

DESCRIPTION OF SYMBOLS 1; Powder administration container 2; Cartridge 10; Nozzle main body 11; Nozzle 12; Syringe part 12a; Concave part 12b; Outer peripheral wall 13; Side wall 22; Communication hole 23; Gap 24; Base 30; Fixing plug 31; Outer wall 31a; Top plate 31b; Locking projection 32; Inner wall 33; Internal thread protrusion 34; Inner nozzle 35; Protrusion 40; 41; Bottle 42; Syringe 43; Opening cylinder part 44; Pusher 50; Cap 51; Trimming part P; Powder

Claims (6)

A cartridge (2) having a pneumatic feeding mechanism (40) for pumping air, a fixing plug (30) engaged with the pneumatic feeding mechanism (40), and a syringe part (12) for storing powder (P) In a powder administration container comprising a combination of
The cartridge (2) includes a concave portion (12a) that is recessed within a predetermined height range of the inner peripheral surface of the syringe portion (12), and an inner plug (20) that is installed inside the syringe portion (12). And
When the cartridge (2) and the fixing plug (30) are combined, the inner plug (20) is pushed up by the protruding portion (35) of the fixing plug (30) and is pumped by the pneumatic feeding mechanism (40). A powder dosing container, characterized in that an air flow passage is formed through which the powder P contained in the syringe part (12) is ejected to the outside by the air.   The powder administration container according to claim 1, wherein a communication hole (22) is formed in the inner plug side wall (21) of the inner plug (20).   The outer diameter of the inner plug side wall (21) of the inner plug (20) is smaller than the inner diameter of the syringe part (12), and there is a gap between the inner plug side wall (21) and the syringe part (12) over the entire circumference. (23) is formed, The powder administration container of Claim 1 by which the recessed part (12a) is intermittently provided in the inner peripheral surface of the said syringe part (12) at intervals in the circumferential direction.   The powder dosing container according to any one of claims 1 to 3, wherein the shape of the upper surface of the inner plug (20) is a conical shape or a truncated cone.   The powder administration container according to any one of claims 1 to 4, wherein the pneumatic feeding mechanism (40) is a squeeze-deformable and recoverable flexible bottle (41).   The powder administration container according to any one of claims 1 to 4, wherein the pneumatic feeding mechanism (40) is a syringe (42) having a movable pusher (44).

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