JP2016130218A5 - - Google Patents

Claims (14)

A method for producing a gel composition containing ferric citrate,
(A) a step of preparing an aqueous solution of thickening polysaccharide , and (B) a step of adding and stirring the ferric citrate to the aqueous solution under heating,
The said manufacturing method including. The manufacturing method of Claim 1 with which the said ferric citrate is contained 5 mass% or more in a gel-like composition. The production method according to claim 1 or 2, wherein the aqueous solution further contains a low-molecular sugar. The manufacturing method as described in any one of Claim 1 to 3 which prepares aqueous solution under a heating. The manufacturing method as described in any one of Claim 1 to 4 whose heating in a process (B) is the range of the temperature of 55 to 100 degreeC. The production method according to any one of claims 1 to 5, wherein the thickening polysaccharide comprises any one of agar , dextrin, xanthan gum, or locust bean gum. The manufacturing method as described in any one of Claim 1 to 6 whose low molecular saccharides are 3 mass parts or more with respect to 1 mass part of this thickening polysaccharide. Further, (C) a step of filling the obtained gel-like composition into a stick-shaped three-side seal to obtain a gel-like composition product,
The manufacturing method as described in any one of Claim 1 to 7 containing this. The manufacturing method as described in any one of Claim 1 to 8 whose gel-like composition is for pharmaceuticals or foodstuffs. A gel-like composition comprising ferric citrate and a thickening polysaccharide, further having the following elution characteristics:
(1) 16th revised Japanese Pharmacopoeia Dissolution Test Method In the dissolution test using the 16th revised Japanese Pharmacopoeia Dissolution Test Dissolution Test Solution II as a test solution and a rotation speed of 50 times / minute, the dissolution time is 30 Iron elution rate in minutes is 75% or more;
(2) 16th revised Japanese Pharmacopoeia Dissolution Test Method According to the paddle method, the 16th revised Japanese Pharmacopoeia Dissolution Test Dissolution Test Solution I is the test solution, and the dissolution rate is 50 times / minute. And / or (3) in the dissolution test in which water is used as a test solution in the 16th revised Japanese Pharmacopoeia dissolution test paddle method and the number of revolutions is 50 times / minute. The elution rate of iron at an elution time of 45 minutes is 80% or more,
The gel-like composition characterized by having. The gel-like composition of Claim 10 in which the said ferric citrate is contained 5 mass% or more. Furthermore, the gel composition of Claim 10 or 11 containing a low molecular sugar. The gel composition according to any one of claims 10 to 12, wherein ferric citrate and thickening polysaccharide are uniformly dispersed and dissolved. The gel composition according to any one of claims 10 to 13, which is used for medicine or food.