JP2016099783A - Solid preparation production system - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a solid preparation production system with high production efficiency.SOLUTION: A solid preparation production system 1 includes: a plurality of production rooms 2, 3, and 4 vertically placed in a building B; preparation facilities 21, 31, and 41 provided in each of the production rooms 2, 3, and 4; transport paths 61 and 62 connecting the production rooms 2, 3, and 4 vertically adjoined; a storeroom 5 adjoining the production rooms 3 and 4; and transportation containers 32a, 32b, and 42 placed above the preparation facilities 21, 31, and 41. The transportation containers 32a, 32b, and 42 may move among the production rooms 2, 3, and 4 and the storeroom 5. An intermediate product discharged from the production rooms 3 and 4 in an upper floor is supplied to the preparation facilities 2 and 3 in a lower floor by dropping through transport paths 62 and 61.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a solid preparation production system.

In the case of producing a solid preparation, the powder as a raw material is sequentially processed by a plurality of preparation facilities to process into a tablet as a final product.
Each preparation facility is generally placed flat on the same floor in the production room.

As a method of moving solid preparations (hereinafter referred to as “intermediate products”) between each flat preparation equipment, they are moved horizontally by a transportation vehicle in a state of being accommodated in a container or the like, and then lift, elevator, stacker A so-called kangaroo method is known in which a crane or the like is lifted above a preparation facility and charged into the preparation facility from above.
In addition, there is a case where a so-called bar chain method is adopted in which each preparation facility is connected by a pipe and the intermediate product is pneumatically transported to reduce the labor and time of transportation.

  In addition, Patent Document 1 uses a stacker crane provided so as to be transportable across a plurality of floors, and transfers intermediate products to production rooms at different levels. In the production room, preparation equipment is provided via transport means such as a chain conveyor. A production system is disclosed in which an intermediate product is introduced into a preparation facility after being transferred to the top of the product.

Japanese Patent No. 4841189

A production system using a kangaroo method requires a lifting machine such as a lift in addition to a transporting vehicle for horizontal movement, which increases equipment costs. In addition, the horizontal movement and the vertical movement need to be repeated, resulting in poor work efficiency.
In addition, the production system using the bar chain system requires a space for installing a device for pneumatic transportation as well as a reduction in operating rate due to cleaning in the pipe. Moreover, the conveyance power has been an obstacle to energy reduction.

  Furthermore, since the production system of Patent Document 1 uses a stacker crane, a chain conveyor, or the like for transportation of intermediate products, it takes time for transportation and power for driving these devices.

  From such a viewpoint, an object of the present invention is to provide a solid preparation production system with high production efficiency.

  The solid preparation production system of the present invention that solves such a problem includes a plurality of production rooms arranged vertically in a building, preparation equipment provided in each production room, and the production rooms adjacent to each other in the vertical direction. The intermediate product discharged | emitted from the said preparation equipment of the upper floor is supplied to the said preparation equipment of a lower floor by dropping the said transportation path.

According to such a solid preparation production system, the intermediate product is supplied by gravity from the preparation equipment arranged on the upper floor to the preparation equipment arranged on the lower floor. Reduction can be achieved.
Further, it is possible to reduce the labor required for transporting the intermediate product and improve the production efficiency.

If it further comprises a storage chamber adjacent to the side of the production chamber and a transfer container that is disposed above the preparation facility and is movable between the production chamber and the storage chamber, It is possible to adjust the timing of supplying the intermediate product to the preparation facility by the container, and the production efficiency can be further improved.
In addition, the intermediate product can be stored in the storage room.

  According to the solid preparation production system of the present invention, it is possible to improve production efficiency.

It is an elevation sectional view showing the solid formulation production system of this embodiment.

The solid formulation production system 1 of the present embodiment is provided in a multi-storey building B as shown in FIG. Although the building B of the present embodiment has a three-story structure, the scale of the building B is not limited.
The solid preparation production system 1 includes production rooms 2, 3, 4, a storage room 5, preparation equipments 21, 31, 41, transport containers 32 a, 32 b, 42, and transport paths 61, 62.

  The production rooms 2, 3, and 4 of this embodiment are formed on each floor of the building B. Production rooms 2, 3, and 4 provided on each floor are adjacent to each other in the vertical direction. That is, the production room 2 on the first floor is formed directly below the production room 3 on the second floor, and the production room 3 on the second floor is formed directly below the production room 4 on the third floor.

  The production rooms 2, 3 and 4 are so-called clean rooms configured to be hermetically sealed. In each of the production chambers 2, 3 and 4, preparation facilities 21, 31, and 41 for producing a solid preparation are provided. A storage room 5 and a machine room (not shown) are provided beside the production rooms 2, 3, 4.

In addition, although this embodiment demonstrates the case where there are three production chambers 2, 3, and 4, the number of production chambers 2, 3, and 4 is not limited. The three production rooms 2, 3 and 4 are provided on the first floor to the third floor, respectively, but if the production rooms 2, 3 and 4 are arranged vertically, the production rooms 2 and 3 , 4 are not limited to the first to third floors. Further, the production room disposed on the lower floor does not necessarily have to be provided directly below the production room on the upper floor.
Furthermore, the number of production rooms provided on each floor is not limited to one room, and a plurality of rooms may be formed on each floor, for example. In this case, it is desirable that the number of production rooms on each floor is the same.

  The storage room 5 is provided adjacent to the production rooms 3 and 4. The production rooms 3 and 4 and the storage room 5 are connected via an opening. Shutters or automatic doors 71, 72, 73 are provided in the opening. The shutters or automatic doors 71, 72, 73 can block the opening. Note that the shutters or automatic doors 71, 72, 73 are normally shielded, and are opened only when the material (transport containers 32a, 32b, 42) is moved between the production chambers 3, 4 and the storage chamber 5. .

The storage chamber 5 is provided with a rack 51 for storing raw materials and intermediate products. The rack 51 can store the transport containers 32a, 32b, and 42 that have moved from the production chambers 3 and 4.
In the present embodiment, a plurality of racks 51, 51 are arranged side by side with a gap in the storage chamber 5. Between the racks 51, a lifting machine (not shown) for moving the transport containers 32a, 32b, and 42 up and down is disposed. In addition, what is necessary is just to install a lifting machine as needed. Further, the number of racks 51 is not limited.

  The rack 51 is formed between the second floor and the third floor. That is, the storage room 5 of this embodiment is continuous from the second floor to the third floor. Note that the storage room 5 and the rack 51 may be divided into floors (second floor and third floor).

Each production room 2, 3, 4 is provided with different preparation facilities 21, 31, 41 for each floor, and is configured so that preparation production proceeds in order from the upper floor (third floor).
The preparation equipments 21, 31, and 41 process materials (raw materials, intermediate products, and the like) input from the transport containers 32a, 32b, and 42. The solid preparation production system 1 of the present embodiment granulates and compresses raw materials, inspects the coated tablets, and further packages them.

  In this embodiment, the tablet printing inspection machine 41, the inspection machine 31, and the packaging machine 21 are arrange | positioned as the formulation equipment 4 in an order from the upper floor (3rd floor). In addition, the kind and number of the preparation equipments 21, 31, and 41 are not limited and may be set as appropriate.

The transport containers 32a, 32b, and 42 transport materials (raw materials and intermediate products) between the production chambers 3 and 4 and the storage chamber 5, supply materials to the preparation facilities 21, 31, and 41, and the like.
The transport containers 32a, 32b, and 42 are so-called flow bins. The flow bin is used as a buffer tank for connection between processes or as a temporary storage container for intermediate products.

  The transfer containers 32a, 32b, and 42 are movable between the production chambers 3 and 4 and the storage chamber 5. The transport containers 32a, 32b, and 42 of the present embodiment move via conveyors 33a, 33b, and 43 provided in the production chambers 3 and 4 and conveyors 52a, 52b, and 52c provided in the storage chamber 5, respectively.

A transport container 42 (hereinafter referred to as “first transport container 42”) provided on the third floor is for transporting tablets from the storage chamber 5 to the tablet printing inspection machine 41, and is provided in the production chamber 4 on the third floor. On the conveyor 43.
The conveyor 43 is installed on a loading stand 44 formed in the production room 4 on the third floor.

The input table 44 is a work table extending from the wall (shutter or automatic door 73) on the storage room 5 side of the production room 4 to above the tablet printing inspection machine 41.
A through hole 45 is formed in the input table 44 corresponding to the position of the material input port 41 a of the tablet printing inspection machine 41. An insertion chute 46 that connects the first transfer container 42 and the material input port 41a is inserted into the through hole 45.

In the storage chamber 5, a conveyor 52 c is disposed corresponding to the position of the conveyor 43. The conveyor 43 and the conveyor 52c are opposed to each other with the shutter or automatic door 73 interposed therebetween, and are continuous by opening the shutter or automatic door 73.
The transport container 42 transports the material between the production chamber 4 and the storage chamber 5 by moving between the production chamber 4 and the storage chamber 5 via the conveyors 43 and 52c.

In the production room 3 on the second floor, there are transport containers 32a and 32b (hereinafter referred to as “second transport container 32a” for the upper transport container and “third transport container” for the lower transport container, respectively) above and below the inspection machine 31. A container 32b ").
The second transport container 32 a receives the tablets discharged from the tablet printing inspection machine 41 and supplies the tablets to the inspection machine 31 or transports them to the storage chamber 5.

The second transfer container 32a is placed on a conveyor 33a provided in the production room 3 on the second floor.
The conveyor 33a is installed on the input stand 34 formed in the production room 3 on the second floor.

The input stand 34 is a work table that extends from the wall (shutter or automatic door 72) on the storage room 5 side of the production room 3 to above the inspection machine 31.
A through hole 35 is formed in the input base 34 corresponding to the position of the material input port 31 a of the inspection machine 31. An insertion chute 36 that connects the second transfer container 32a and the material input port 31a is inserted into the through hole 35.

In the storage room 5, a conveyor 52b is disposed corresponding to the position of the conveyor 33a. The conveyor 33a and the conveyor 52b are opposed to each other with the shutter or automatic door 72 interposed therebetween, and are continuous by opening the shutter or automatic door 72.
The transfer container 32a moves between the production chamber 3 and the storage chamber 5 via the conveyors 33a and 52b, thereby transferring the material between the production chamber 3 and the storage chamber 5.

The third transport container 32b moves in the lateral direction by the conveyor 33b provided on the floor surface of the production room 3 on the second floor, and moves up and down in the vicinity of the inspection machine 31.
The third transport container 32 b is disposed at a position lower than the inspection machine 31 by entering the recess 37 formed on the floor surface in the vicinity of the inspection machine 31.

A through hole 38 is formed at the bottom of the recess 37 corresponding to the position of the material input port 21 a of the packaging machine 21. A transport path 62 that connects the third transport container 32b and the material input port 21a is inserted into the through hole 38.
The concave portion 37 may be formed as necessary. The third transfer container 32b may be disposed in the production room 2 on the first floor.

In the storage room 5, a conveyor 52a is disposed corresponding to the position of the conveyor 33b. The conveyor 33b and the conveyor 52a are opposed to each other with the shutter or automatic door 71 interposed therebetween, and are continuous by opening the shutter or automatic door 71.
The transport container 32b moves between the production chamber 3 and the storage chamber 5 via the conveyors 33b and 52a, thereby transporting the material between the production chamber 3 and the storage chamber 5.

A transportation path 62 is disposed between the production room 3 on the second floor and the production room 4 on the third floor.
The transport path 62 is configured to be able to connect the discharge port 41b of the tablet printing inspection machine 41 and the second transporter 32a. That is, the transport path 62 guides the tablets discharged from the discharge port 41b of the tablet printing inspection machine 41 to the second transport container 32a.

The tablets are dropped into the transport path 62, and are put into the second transport container 32a. And the tablet in the 2nd conveyance container 32a is thrown into the test | inspection machine 31 through the insertion chute | shoot 36. FIG.
The transport path 62 is configured by a pipe, a vinyl tube, or the like that is provided with measures for preventing tablet breakage.

A transportation path 61 is disposed between the production room 3 on the second floor and the production room 2 on the first floor.
The transport path 61 is configured to be able to connect the third transporter 32 b and the insertion port 21 a of the packaging machine 21. That is, the transport path 61 guides the tablets supplied from the inspection machine 31 to the third transport container 32 b to the packaging machine 21.

The tablets are dropped into the packaging path 21 by dropping through the transport path 61.
The transport path 61 is configured by a pipe, a vinyl tube, or the like that has been provided with measures for preventing tablet breakage.

The preparation by the solid preparation production system 1 of the present embodiment is performed according to the following procedure.
First, the first transport container 42 loaded with tablets is moved above the tablet printing inspection machine 41 in the production chamber 4 from the storage chamber 5 using the conveyors 43 and 52c.

  Next, the tablet printing inspection machine 41 is driven by the power applied from the machine room, the discharge port (bottom) of the first transport container 42 is opened, and the tablets in the first transport container 42 are loaded into the loading chute 46. . Then, the tablet falls on the loading chute 46 and is loaded into the tablet printing inspection machine 41.

The tablet (intermediate product) processed by the tablet printing inspection machine 41 is discharged from the discharge port 41b, dropped along the transport path 62, and put into the second transport container 32a.
Subsequently, the discharge port (bottom) of the second transport container 32 a is opened, and the tablets in the second transport container 32 a are loaded into the loading chute 36. Then, the tablet falls on the input chute 36 and is input to the inspection machine 31. That is, the tablets discharged from the tablet printing inspection machine 41 fall on the transport path 62 and the input chute 36 and are supplied to the inspection machine 31.

  The second transport container 32a puts the tablet into the feeding chute 36 at an arbitrary timing. The timing at which the tablets are put in is appropriately set according to the relationship between the amount of tablets held by the second transport container 32a and the processing capability of the inspection machine 31. That is, when continuously inspecting tablets, the tablets are continuously fed into the inspection machine 31 from the second transport container 32a. Note that the tablet may be temporarily stored in the storage chamber 5 by moving the second transport container 32 a to the storage chamber 5.

The inspection machine 31 inspects the quality (breakage or chipping) of the tablet.
The tablet confirmed to be normal by the inspection machine 31 is discharged from the discharge port 31b, and dropped into the third transport container 32b by dropping the bowl-shaped charging chute 39.

  Next, the discharge port (bottom) of the third transport container 32 b is opened, and the tablets in the third transport container 32 b are put into the lower pipe-shaped transport path 61. The tablets fall on the conveyance path 61 and are put into the packaging machine 21. That is, the tablets discharged from the inspection machine 31 fall on the input chute 39 and the conveyance path 61 and are supplied to the packaging machine 21.

  The third transport container 32b puts the tablet into the transport path 61 at an arbitrary timing. The timing at which the tablets are put in is appropriately set in accordance with the relationship between the amount of tablets held by the third transport container 32b and the processing capability of the packaging machine 21. Note that the tablet may be temporarily stored by moving the third transport container 32b to the storage chamber 5.

  The packaging machine 21 packages a product (tablet). In addition, although the packaging method of a product is not limited, In this embodiment, the PTP packaging (Press Through Package) which wraps a tablet separately is employ | adopted.

According to the solid preparation production system 1 of the present embodiment, since the intermediate product is supplied by gravity from the preparation equipment arranged on the upper floor to the preparation equipment arranged on the lower floor, the conveyance power is minimized. With this, power energy can be reduced.
Further, it is possible to reduce the labor required for transporting the intermediate product and improve the production efficiency.

Moreover, production efficiency can be improved more by adjusting the timing which supplies an intermediate product to the formulation equipment of a lower floor with a conveyance container.
In addition, since the intermediate product can be stored in the storage chamber 5, the preparation production cycle can be easily adjusted.

  Moreover, since the floor area of the production rooms 2, 3, and 4 can be reduced by arranging the preparation facilities 21, 31, and 41 above and below, the preparation can be performed even in a place where the site area is limited. Production can be performed.

The transport paths 61 and 62 connect the preparation facilities disposed vertically to each other with the shortest distance. Further, since the intermediate product transported through the transport paths 61 and 62 falls due to gravity, adhesion to the transport paths 61 and 62 can be minimized.
Therefore, it is possible to shorten the cleaning time of the conveyance paths 61 and 62 and improve the cleaning performance, and it is possible to efficiently produce multi-item products.

  The embodiment of the present invention has been described above. However, the present invention is not limited to the above-described embodiments, and the above-described constituent elements can be appropriately changed without departing from the spirit of the present invention.

For example, the transport container may be provided as necessary, and the preparation facilities may be directly connected to each other by a transportation route.
In addition, the timing of introducing the intermediate product may be adjusted by providing an opening / closing valve in the transportation path.
Moreover, the product produced by the solid preparation production system is not limited.

1 Solid formulation production system 2 Production room 21 Packaging machine (formulation equipment)
3 Production rooms 31 Inspection machines (formulation equipment)
32a Second transport container (transport container)
32b Third transport container (transport container)
4 Production room 41 Tablet printing inspection machine (formulation equipment)
42 First transport container (transport container)
5 Storage room 61, 62 Transport route B Building

Claims (2)

A plurality of production rooms arranged above and below the building;
Formulation equipment provided in each production room,
A solid preparation production system comprising: a transportation path that connects between the production chambers adjacent to each other vertically;
An intermediate product discharged from the preparation facility on the upper floor is supplied to the preparation facility on the lower floor by dropping the transport path. A storage room adjacent to the production room;
A transport container disposed above the preparation facility,
The solid preparation production system according to claim 1, wherein the transport container is movable between the production chamber and the storage chamber.

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