JP2016049183A5

JP2016049183A5 -

Info

Publication number: JP2016049183A5
Application number: JP2014174978A
Authority: JP
Filing date: 2014-08-29
Publication date: 2017-10-05
Anticipated expiration: 2034-08-29

Description

図１において、眼科装置２０は、処理装置１０、平面画像撮影装置３及び表示部４を含む。処理装置１０は、画像処理や収差補正係数の演算などを行う。平面画像撮影装置３は、ＡＯ−ＳＬＯ像やＷＦ−ＳＬＯ像などの平面画像の撮影を行う。表示部４は、処理装置１０の演算結果などをユーザーに提示する。さらに眼科装置２０は、外部のデータベース（以下ＤＢと称する。）１に接続される。これにより、処理装置１０はＤＢ１に保存されている他のモダリティで取得された画像や患者データ、他の平面画像撮影装置で取得された過去の画像やデータ、及びＯＣＴ２により得た断層像等を取得することができる。 In FIG. 1, the ophthalmologic apparatus 20 includes a processing device 10, a planar image photographing device 3, and a display unit 4. The processing device 10 performs image processing and calculation of aberration correction coefficients. The planar image capturing device 3 captures a planar image such as an AO-SLO image or a WF-SLO image. The display unit 4 presents the calculation result of the processing device 10 to the user. Further, the ophthalmologic apparatus 20 is connected to an external database (hereinafter referred to as DB) 1. As a result, the processing apparatus 10 displays images and patient data acquired by other modalities stored in the DB1, past images and data acquired by other planar image capturing apparatuses, and tomographic images obtained by the OCT2. Can be acquired.

出力部１５０は、ＷＦ−ＳＬＯ像に対応づけられた正常な視細胞層が存在する領域をモニタ等に出力する。或いは、ユーザーが指定した撮影位置のＡＯ−ＳＬＯの制御方法を不図示の収差補正を行う構成等の各種モダリティに指定する。ＡＯ制御部１６０は、収差補正に関わるゼルニケ係数の計算を行う。本実施例では、平面画像撮影装置３に加え、ＡＯ制御部１６０を含めて被検眼眼底の小領域の平面画像を取得する平面画像取得手段を構成する。該平面画像取得手段では、位置合わせ部１４２が対応づけた視細胞の状態に関する情報に基づいて、ＷＦ−ＳＬＯ像上の撮影位置における収差補正法を変えて、ＡＯ−ＳＬＯ像を取得する。 The output unit 150 outputs a region where a normal photoreceptor layer associated with a WF-SLO image exists to a monitor or the like. Alternatively, the control method of the AO-SLO at the photographing position designated by the user is designated for various modalities such as a configuration for performing aberration correction (not shown). The AO control unit 160 calculates Zernike coefficients related to aberration correction. In the present embodiment, in addition to the planar image capturing device 3, a planar image acquisition unit that includes the AO control unit 160 and acquires a planar image of a small region of the fundus of the eye to be examined is configured. The planar image acquisition means acquires an AO-SLO image by changing the aberration correction method at the photographing position on the WF-SLO image based on the information about the state of the photoreceptor cell associated by the alignment unit 142.

Claims

Tomographic image acquisition means for acquiring a tomographic image of the fundus of the eye to be examined;
Layer analysis means for extracting information on the state of photoreceptor cells from the tomogram,
Alignment means for associating the information on the state of the photoreceptor cells with the information on the photographing position on the planar image of the fundus;
Plane image acquisition means for acquiring a plane image of the imaging position on the fundus of the eye to be examined by changing the aberration correction method at the imaging position based on information relating to the state of the photoreceptor cell associated by the alignment means;
An ophthalmologic apparatus comprising:

The information about the photoreceptor cell is whether or not an IS / OS layer exists,
The ophthalmic apparatus according to claim 1, wherein the layer analysis unit extracts the IS / OS layer and identifies a region where the IS / OS layer exists and a region where the IS / OS layer does not exist.

The layer analysis means extracts the RPE layer when the IS / OS layer does not exist, and the IS / OS layer and the RPE near the boundary between the region where the IS / OS layer exists and the region where the IS / OS layer does not exist. The ophthalmic apparatus according to claim 2, wherein a position where the IS / OS layer is present in a region where the IS / OS layer is not present is estimated based on a distance from the layer.

Display control means for displaying the planar image acquired by the planar image acquisition means on a display means;
The information about the photoreceptor cell is whether or not an IS / OS layer exists,
The planar image acquisition means acquires a planar image of the photographing positions having different focus positions when the IS / OS layer exists,
The ophthalmology according to any one of claims 1 to 3, wherein the display control unit causes the display unit to display a plane image selected from a plurality of the acquired plane images based on frequency analysis. apparatus.

The information about the photoreceptor cell is whether or not an IS / OS layer exists,
The planar image acquisition means acquires the planar image having a plurality of different focus positions in the vicinity of the boundary between the region where the IS / OS layer exists and the region where the IS / OS layer does not exist, and performs frequency analysis from the plurality of the acquired planar images The ophthalmologic apparatus according to any one of claims 1 to 4, wherein the boundary is obtained based on the equation (1).

The information about the photoreceptor cell is whether or not an IS / OS layer exists,
When the IS / OS layer does not exist, the planar image acquisition means uses a Zernike used when acquiring the planar image using a part of the aberration correction parameters calculated at the position where the IS / OS exists. The coefficient is acquired, The ophthalmologic apparatus as described in any one of Claims 1 thru | or 5 characterized by the above-mentioned.

The present invention further comprises presenting means for presenting to the user as an area in which aberration correction may not be successful when the layer analyzing means acquires the lesioned part of the eye to be examined extracted from the tomographic image as the planar image. Item 7. The ophthalmologic apparatus according to any one of Items 1 to 6.

The tomographic image obtaining means for obtaining a fundus sectional Sozo of the eye,
Layer analysis means for extracting information on the state of photoreceptor cells from the tomogram,
Alignment means for associating the information on the state of the photoreceptor cells with the information of the photographing position on the planar image of the fundus;
By changing the imaging position on the plane image image of the fundus said positioning means based on the information about the state of the visual cells which associates, the planar image of the imaging position of the are aberration correction of the eye the fundus Planar image acquisition means for acquiring;
An ophthalmologic apparatus comprising:

The planar image acquisition means, so as to include the entire area on the visual plane picture image state on the basis of the information about the determined the fundus and the photoreceptor cells are present in the cell, setting a plurality of photographing positions The ophthalmic apparatus according to claim 8.

The planar image acquisition means, setting a plurality of photographing positions along the boundary of the region on the photoreceptor cell states for the plane image of the fundus is determined that the visual cell is present based on the information image The ophthalmic apparatus according to claim 8.

The planar image acquisition means, when the imaging position is set along the boundary of the region where the photoreceptor cell is determined to be present, is focused in the region where the photoreceptor cell exists in the vicinity of the imaging position position and, in a plurality of focus positions vertically of the region in a depth direction in the plane image before Symbol photographing position, according to claim 10, characterized in that to obtain a flat image of the imaging position of the fundus Ophthalmic equipment.

A program for causing a computer to execute processing of each unit in the ophthalmic apparatus according to any one of claims 1 to 11.

A storage medium storing the program according to claim 12.

A tomographic image acquisition step of acquiring a tomographic image of the fundus of the subject eye;
A layer analysis step of extracting information on the state of photoreceptor cells from the tomographic image;
An alignment step for associating the information on the state of the photoreceptor cells with the information on the photographing position on the planar image of the fundus;
A plane image acquisition step of acquiring a plane image of the imaging position on the fundus of the eye to be examined by changing the aberration correction method at the imaging position based on information relating to the state of the photoreceptor cell associated in the alignment step;
A method for controlling an ophthalmic apparatus, comprising:

And the tomographic image obtaining step of obtaining fundus sectional Sozo of the eye,
A layer analysis step of extracting information on the state of photoreceptor cells from the tomographic image;
An alignment step for associating information on the state of the photoreceptor cells with information on a photographing position on the planar image of the fundus;
By changing the imaging position on the plane image image of the fundus on the basis of information about the state of the visual cells which associates in the alignment step, the planar image of the imaging position of the are aberration correction of the eye the fundus A planar image acquisition step to acquire;
A method for controlling an ophthalmic apparatus, comprising: