JP2016024070A5 - - Google Patents
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- JP2016024070A5 JP2016024070A5 JP2014148632A JP2014148632A JP2016024070A5 JP 2016024070 A5 JP2016024070 A5 JP 2016024070A5 JP 2014148632 A JP2014148632 A JP 2014148632A JP 2014148632 A JP2014148632 A JP 2014148632A JP 2016024070 A5 JP2016024070 A5 JP 2016024070A5
- Authority
- JP
- Japan
- Prior art keywords
- electric field
- enhancing element
- raman spectroscopic
- field enhancing
- nhcoch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000005684 electric field Effects 0.000 claims 12
- 230000002708 enhancing Effects 0.000 claims 7
- 238000001069 Raman spectroscopy Methods 0.000 claims 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 208000006673 Asthma Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 210000003437 Trachea Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000001678 irradiating Effects 0.000 claims 1
- 230000003287 optical Effects 0.000 claims 1
Claims (11)
前記金属微細構造体の表面に配置された修飾分子と、
を含み、
前記修飾分子は、下記式(1)、下記式(2)、または下記式(3)で表される化合物に由来する、電場増強素子。
X1は、−NH2、−(CxH2x)−R、−(NHCOCH2)−(CyH2y)−R、または−OCH2−(CzH2z)−Rであり、
X2は、−H、−OH、−NH2、−OCH3、−NHCOCH3、または−(CwH2w)−CH3であり、
Rは、−NH2、−COOH、−SH、−CHO、または−CH(NH2)−COOHであり、
xは、1以上17以下の整数であり、
yは、0以上14以下の整数であり、
zは、0以上15以下の整数であり、
wは、0以上3以下の整数である。 A metal microstructure,
A modifying molecule disposed on the surface of the metal microstructure;
Including
The modifying molecule is an electric field enhancing element derived from a compound represented by the following formula (1), the following formula (2), or the following formula (3).
X1 is, -NH 2, - (C x H 2x) -R, - (NHCOCH 2) - (C y H 2y) -R, or -OCH 2 - is (C z H 2z) -R,
X2 is, -H, -OH, -NH 2, -OCH 3, -NHCOCH 3 or - a (C w H 2w) -CH 3 ,
R is -NH 2, -COOH, -SH, -CHO or -CH (NH 2) -COOH,,
x is an integer of 1 to 17,
y is an integer of 0 to 14,
z is an integer of 0 to 15,
w is an integer of 0 or more and 3 or less.
X2は、−OH、−NH2、−OCH3、−NHCOCH3、または−(CwH2w)−CH3である、電場増強素子。 In claim 1,
X2 is, -OH, -NH 2, -OCH 3 , -NHCOCH 3 or is - (C w H 2w) -CH 3 , electric field enhancement device.
X2は、−OH、−NH2、または−CH3である、電場増強素子。 In claim 1 or 2,
X2 is, -OH, -NH 2, or -CH 3, electric field enhancement device.
X1は、−NH2、−(CH2)−R、−(NHCOCH2)−R、または−OCH2−Rである、電場増強素子。 In any one of Claims 1 thru | or 3,
X1 is, -NH 2, - (CH 2 ) -R, - (NHCOCH 2) -R, or -OCH 2 -R, electric field enhancement device.
前記修飾分子は、上記式(2)で表される化合物に由来する、電場増強素子。 In any one of Claims 1 thru | or 4,
The electric field enhancing element is derived from the compound represented by the formula (2) .
前記修飾分子は、チロシンに由来する、電場増強素子。 In any one of Claims 1 thru | or 5,
The modifying molecule is an electric field enhancing element derived from tyrosine.
前記電場増強素子に光を照射する光源と、
前記電場増強素子から放射される光を検出する光検出器と、
を含む、ラマン分光装置。 The electric field enhancing element according to any one of claims 1 to 6,
A light source for irradiating the electric field enhancing element with light;
A photodetector for detecting light emitted from the electric field enhancing element;
Including a Raman spectroscopic apparatus.
前記光源から射光された光を前記電場増強素子に導き、且つ前記電場増強素子から放射される光を前記光検出器に導くハーフミラーをさらに備える、ラマン分光装置。A Raman spectroscopic apparatus, further comprising a half mirror that guides light emitted from the light source to the electric field enhancement element and guides light emitted from the electric field enhancement element to the photodetector.
前記電場増強素子から放射される光からレイリー散乱光を除外する光学フィルターをさらに備える、ラマン分光装置。The Raman spectroscopic apparatus further comprising an optical filter that excludes Rayleigh scattered light from light emitted from the electric field enhancing element.
前記光検出器からの検出情報に基づいて健康医療情報を演算する演算部と、
前記健康医療情報を記憶する記憶部と、
前記健康医療情報を表示する表示部と、
を含む、電子機器。 The Raman spectroscopic device according to any one of claims 7 to 9 ,
A computing unit that computes health and medical information based on detection information from the photodetector;
A storage unit for storing the health care information;
A display unit for displaying the health care information;
Including electronic equipment.
前記健康医療情報は、NO分子の量に基づいて演算された、喘息による気管の炎症の度合い、を含む、電子機器。The health care information includes an electronic device including a degree of inflammation of the trachea caused by asthma calculated based on the amount of NO molecules.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014148632A JP6418379B2 (en) | 2014-07-22 | 2014-07-22 | Electric field enhancement element, Raman spectroscopic device, and electronic equipment |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014148632A JP6418379B2 (en) | 2014-07-22 | 2014-07-22 | Electric field enhancement element, Raman spectroscopic device, and electronic equipment |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2016024070A JP2016024070A (en) | 2016-02-08 |
JP2016024070A5 true JP2016024070A5 (en) | 2017-08-03 |
JP6418379B2 JP6418379B2 (en) | 2018-11-07 |
Family
ID=55270935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014148632A Active JP6418379B2 (en) | 2014-07-22 | 2014-07-22 | Electric field enhancement element, Raman spectroscopic device, and electronic equipment |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP6418379B2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6586867B2 (en) | 2015-12-08 | 2019-10-09 | セイコーエプソン株式会社 | Electric field enhancing element and Raman spectrometer |
JP2017150865A (en) * | 2016-02-23 | 2017-08-31 | コニカミノルタ株式会社 | Gas detection method and gas detection device |
RU2766343C1 (en) * | 2020-12-16 | 2022-03-15 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт органической химии и технологии" (ФГУП "ГосНИИОХТ") | Method of producing grc-chip for immunochemical analysis |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006266707A (en) * | 2005-03-22 | 2006-10-05 | Fuji Photo Film Co Ltd | Biosensor |
JP4231888B2 (en) * | 2005-11-25 | 2009-03-04 | 富士フイルム株式会社 | Biosensor manufacturing method |
US8903474B2 (en) * | 2005-12-06 | 2014-12-02 | Pen Inc. | Analysis of gases |
EP2344879A4 (en) * | 2008-09-15 | 2013-03-20 | Platypus Technologies Llc | Detection of vapor phase compounds by changes in physical properties of a liquid crystal |
JP2014119263A (en) * | 2012-12-13 | 2014-06-30 | Seiko Epson Corp | Optical device, detection device, electronic device and optical device manufacturing method |
-
2014
- 2014-07-22 JP JP2014148632A patent/JP6418379B2/en active Active
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