JP2015506990A5 - - Google Patents
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- Publication number
- JP2015506990A5 JP2015506990A5 JP2014556894A JP2014556894A JP2015506990A5 JP 2015506990 A5 JP2015506990 A5 JP 2015506990A5 JP 2014556894 A JP2014556894 A JP 2014556894A JP 2014556894 A JP2014556894 A JP 2014556894A JP 2015506990 A5 JP2015506990 A5 JP 2015506990A5
- Authority
- JP
- Japan
- Prior art keywords
- membered
- optionally substituted
- aliphatic
- aryl
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000006708 (C5-C14) heteroaryl group Chemical group 0.000 claims 7
- 125000005915 C6-C14 aryl group Chemical group 0.000 claims 7
- 125000000623 heterocyclic group Chemical group 0.000 claims 7
- 125000001931 aliphatic group Chemical group 0.000 claims 5
- 125000004452 carbocyclyl group Chemical group 0.000 claims 4
- 125000004429 atom Chemical group 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 239000007864 aqueous solution Substances 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 239000002105 nanoparticle Substances 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 239000008180 pharmaceutical surfactant Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2012/000190 WO2013120229A1 (en) | 2012-02-17 | 2012-02-17 | METHOD FOR PREPARING AQUEOUS MANO PARTICLE SUSPENSIONS OF DERIVATIVES OF 4,9-DIHYDROXY-NAPHTHO[2,3-b]FURAN ALIPHATIC ACID ESTERS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015506990A JP2015506990A (ja) | 2015-03-05 |
| JP2015506990A5 true JP2015506990A5 (cg-RX-API-DMAC7.html) | 2015-04-16 |
Family
ID=48983518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014556894A Pending JP2015506990A (ja) | 2012-02-17 | 2012-02-17 | ４，９−ジヒドロキシ−ナフト［２，３−ｂ］フラン脂肪族酸エステルの誘導体の水性ナノ粒子懸濁液を調製する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20150164794A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2814480A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2015506990A (cg-RX-API-DMAC7.html) |
| CN (1) | CN104080449A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013120229A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015272560B2 (en) | 2014-06-09 | 2019-02-14 | Kyoto Pharmaceutical Industries, Ltd. | Novel anticancer agent |
| US10183925B2 (en) | 2015-03-27 | 2019-01-22 | Boston Biomedical, Inc. | Substituted naphtho[2,3-b]furans as water-soluble prodrugs for preventing and/or treating cancer |
| JP6810036B2 (ja) * | 2015-07-17 | 2021-01-06 | 大日本住友製薬株式会社 | ２−アセチル−４Ｈ，９Ｈ−ナフト［２，３−ｂ］フラン−４，９−ジオンの製造方法 |
| CN111295368A (zh) | 2017-09-22 | 2020-06-16 | 大日本住友制药株式会社 | 化学活化型水溶性前药 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04139177A (ja) * | 1989-12-28 | 1992-05-13 | Dainippon Ink & Chem Inc | フラルベンゾキノン誘導体及びその製造方法並びに制癌剤 |
| WO2008149192A2 (en) * | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
| CA2736563C (en) * | 2007-09-10 | 2016-01-26 | Boston Biomedical, Inc. | A novel group of stat3 pathway inhibitors and cancer stem cell pathway inhibitors |
| US9150530B2 (en) * | 2011-03-04 | 2015-10-06 | Zhoushan Haizhongzhou Xinsheng Pharmaceuticals Co., Ltd. | Esters of 4, 9-dihydroxy-naphtho [2, 3-b] furans for disease therapies |
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2012
- 2012-02-17 JP JP2014556894A patent/JP2015506990A/ja active Pending
- 2012-02-17 WO PCT/CN2012/000190 patent/WO2013120229A1/en not_active Ceased
- 2012-02-17 CN CN201280066774.3A patent/CN104080449A/zh active Pending
- 2012-02-17 US US14/379,247 patent/US20150164794A1/en not_active Abandoned
- 2012-02-17 EP EP12868478.4A patent/EP2814480A4/en not_active Withdrawn