JP2015183001A5 - - Google Patents
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- Publication number
- JP2015183001A5 JP2015183001A5 JP2014080540A JP2014080540A JP2015183001A5 JP 2015183001 A5 JP2015183001 A5 JP 2015183001A5 JP 2014080540 A JP2014080540 A JP 2014080540A JP 2014080540 A JP2014080540 A JP 2014080540A JP 2015183001 A5 JP2015183001 A5 JP 2015183001A5
- Authority
- JP
- Japan
- Prior art keywords
- warfarin
- solid preparation
- salt
- preparation according
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007787 solid Substances 0.000 claims 14
- 238000002360 preparation method Methods 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 6
- 229960005080 warfarin Drugs 0.000 claims 6
- PJVWKTKQMONHTI-UHFFFAOYSA-N warfarin Chemical compound OC=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 PJVWKTKQMONHTI-UHFFFAOYSA-N 0.000 claims 6
- 238000009472 formulation Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 238000007908 dry granulation Methods 0.000 claims 2
- 239000004503 fine granule Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- WSHYKIAQCMIPTB-UHFFFAOYSA-M potassium;2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate Chemical compound [K+].[O-]C=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 WSHYKIAQCMIPTB-UHFFFAOYSA-M 0.000 claims 2
- 229960000883 warfarin potassium Drugs 0.000 claims 2
- 239000000945 filler Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014080540A JP6304751B2 (ja) | 2014-03-24 | 2014-03-24 | ワルファリン含有固形製剤及びその製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014080540A JP6304751B2 (ja) | 2014-03-24 | 2014-03-24 | ワルファリン含有固形製剤及びその製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015183001A JP2015183001A (ja) | 2015-10-22 |
| JP2015183001A5 true JP2015183001A5 (enExample) | 2017-05-18 |
| JP6304751B2 JP6304751B2 (ja) | 2018-04-04 |
Family
ID=54349944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014080540A Active JP6304751B2 (ja) | 2014-03-24 | 2014-03-24 | ワルファリン含有固形製剤及びその製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6304751B2 (enExample) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5041430A (en) * | 1989-09-18 | 1991-08-20 | Du Pont Mereck Pharmaceutical Company | Oral anticoagulant/platelet inhibitor low dose formulation |
| JP4783573B2 (ja) * | 2004-02-20 | 2011-09-28 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ワルファリンカリウム含有医薬組成物とその製造方法 |
-
2014
- 2014-03-24 JP JP2014080540A patent/JP6304751B2/ja active Active
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