JP2015142613A - Medical agent injection tool for living body and medical agent injection tool kit for living body - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a medical agent injection tool for a living body and a medical agent tool kit for a living body which enables pushing out the medical agent remained in a tubular body with an easily operation, thereby improving an usage rate of the medical agent.SOLUTION: A medical agent injection tool 100 for a living body includes: a tubular body having a plurality of lumens 100; and a connection part 24 having a plurality of medical agent paths 20 communicating a plurality of medical agent outlets 16 and a plurality of syringe fitting ports 18 and an air inlet 22 for inhaling the air from the outside towards the syringe fitting port 18 by having the syringe fitting port 18 in a negative pressure. The medical agent paths 20 includes, at a downstream of the air inlet 22, first control means 26 for controlling an outflow of the medical agent from the side of the lumens 10 to the side of the syringe fitting port 18. The air inlet 22 includes second control means 28 for controlling an outflow of the medical agent from the air inlet 22 to the outside.

Description

  The present invention relates to a biological fluid injection tool and a biological fluid injection tool kit for injecting a plurality of chemical fluids into an affected area of a living body. More specifically, the present invention relates to a biomedical solution injection for injecting a chemical solution by allowing a tubular body having two or more lumens to reach the inside of a living body directly or by inserting it into a forceps hole of an endoscope or the like. The present invention relates to a tool and a biomedical solution injection tool kit.

  In a treatment or therapy in a living body, it may be required to inject a plurality of drug solutions simultaneously or continuously into a desired region in the living body. For example, a biological tissue adhesive applicator that is applied while mixing two drug solutions in a treatment such as resection stump of the liver or lung or hemostasis closure of a sutured portion of the digestive tract is known (for example, Patent Document 1).

  A biological tissue adhesive applicator disclosed in Patent Document 1 (hereinafter also referred to as “Prior Art 1”) includes a plurality of chemical solution injection ports, a plurality of chemical solution discharge ports, and these in a nozzle body having a space inside. And a chemical solution distribution pipe communicating therewith. In the vicinity of the chemical solution outlet, there is provided a gas outlet for injecting gas filled in the nozzle body from the gas inlet and spraying and mixing the chemical solution discharged from the chemical outlet. In addition, as a specific aspect, the related art 1 shows an example in which different chemical solutions are filled and a plurality of syringe main bodies connected to each of the plurality of chemical solution injection ports are provided. With this configuration, the related art 1 enables a plurality of chemical liquids to be simultaneously ejected in a mist form from a plurality of chemical liquid discharge ports by pressing a plunger provided on the syringe.

  The chemical solution circulation pipe in the prior art 1 is provided with a communication port through which the inside of the nozzle body communicates with the inside of the chemical solution circulation pipe, and gas inside the nozzle body is introduced toward the chemical solution discharge port. At the time of discharging the chemical liquid, the discharge pressure of the chemical liquid is higher than the gas pressure inside the nozzle body, so that the gas does not flow into the chemical liquid distribution pipe from the flow port. On the other hand, when the discharge of the chemical liquid is stopped, the communication port opens due to the gas pressure of the gas filled in the space of the nozzle body, the gas flows into the chemical liquid distribution pipe, and the chemical liquid at the tip side of the communication port is externally Is disclosed in Patent Document 1. With this configuration, the related art 1 prevents solidification due to contact between the chemical solutions at the nozzle tips during intermittent use when a chemical solution that mixes a plurality of solutions at the time of bonding is used.

JP 2012-1000085 A1

  However, the prior art 1 has the following problems. That is, in the prior art 1, when the discharge of the chemical solution is stopped, the communication port is opened by the gas pressure of the gas filled in the space of the nozzle body, and the gas flows into the chemical solution distribution pipe from the communication port. Here, in the prior art 1, as shown in FIG. 5 (b) in Patent Document 1, a check valve is provided on the upstream side from the communication port, and the gas flowing in from the communication port does not go into the syringe but downstream. It is configured to go to the side (tip side). As a result, in the prior art 1 when the discharge of the chemical liquid is stopped, the chemical liquid remains in the chemical liquid distribution pipe on the upstream side of the communication port.

  Therefore, when the prior art 1 is discarded, the remaining chemical solution must be discarded at the same time. On the other hand, it has been required to reduce the amount of unused chemical solution to be discarded and improve the usage rate of the chemical solution.

  In the prior art 1, a method of removing the syringe from the nozzle body at one end, filling the syringe with air, connecting it to the nozzle body again, and then flowing the air into the drug solution flow pipe to push out the drug solution may be considered. . However, when this method is implemented, it is not preferable in that a complicated operation of removing and connecting the syringe to the nozzle body occurs.

  The present invention has been made in view of the above problems. That is, the present invention provides a biomedical solution infusion tool and a biomedical solution infusion tool kit that can extrude a medicinal solution remaining in a tubular main body with a simple operation and thereby improve the usage rate of the medicinal solution. Let it be an issue.

  The biological fluid injection device of the present invention includes a tubular body having a plurality of lumens therein, a plurality of drug solution outlets communicating with each of the plurality of lumens, and a plurality of syringes for injecting a drug solution into each of the plurality of lumens A plurality of syringe mounting ports for mounting a plurality of, a plurality of chemical liquid flow paths communicating the plurality of the chemical solution discharge ports and the plurality of syringe mounting ports, and a plurality of the syringe mounting ports communicating with the outside and the plurality of syringe mounting ports A connecting portion having a gas suction hole for sucking gas from the outside toward the syringe mounting port by making the mouth a negative pressure, and the connection portion is located downstream of the gas suction hole. And a first restricting means for restricting the chemical liquid from flowing out from the lumen side to the syringe mounting port side, and the gas suction hole is configured so that the chemical liquid is the gas suction hole or not. And having a second regulating means for regulating the flow out to the outside.

  The biomedical solution injection tool kit of the present invention includes the biomedical solution injection device of the present invention, a syringe body that can contain a drug solution or gas, and a gas or fluid that is attached to the syringe mounting port and that is attached to the syringe body. A plurality of syringes having an inlet / outlet for inflow or outflow and an operation unit for performing an operation for inflowing / outflowing of fluid to / from the syringe main body through the inlet / outlet are provided.

  The biomedical liquid injection tool and the biomedical liquid injection tool kit of the present invention can discharge the chemical liquid remaining in the lumen from the tip of the lumen only by operating the syringe mounted on the syringe mounting port. That is, it is possible to use the chemical solution remaining in the lumen only by a simple operation of operating the syringe, thereby improving the usage rate of the chemical solution.

It is sectional drawing which shows the state which cut | disconnected the chemical | medical solution injection tool for biological bodies which illustrates the 1st embodiment of this invention along the flow path of a chemical | medical solution. It is a perspective view of the connection part in the first embodiment of the present invention, and the upper half in the upper direction of the drawing is omitted. [BRIEF DESCRIPTION OF THE DRAWINGS] It is a front view which shows an example of the biomedical-solution injection tool kit of this invention formed by mounting | wearing the biomedical-solution injection tool which is the 1st embodiment of this invention with a syringe. It is explanatory drawing explaining the use condition of the biological fluid injection tool which is the first embodiment of this invention, (a) is the state which pushed the plunger provided in the syringe and discharged the chemical | medical solution with which the said syringe was discharged. (B) shows the state which pulled the plunger after the state shown to (a), and suck | inhaled gas in the syringe from the gas suction hole. (A) is a top view of the common operation surface in one mode of the operation unit connecting member, and FIG. 5 (b) is a side view in another mode of the operation unit connecting member. It is a front view which shows an example of the biomedical-solution tool kit of this invention formed by mounting | wearing with the syringe in the modification of the biomedical-solution injection tool which is 1st embodiment of this invention. (A) is a fragmentary perspective view which shows the part provided with the gas suction hole of the connection part in the biological fluid injection tool which is 1st embodiment, (b) is II sectional drawing in (a), (C) is II sectional drawing in (a), Comprising: The state which the fluid flows in the inside of a chemical | medical solution flow path from an upstream direction toward a downstream direction is shown. .

The biomedical solution injection device of the present invention appropriately regulates the flow of a chemical solution or gas generated by a simple operation of operating a mounted syringe by the first regulating member and the second regulating member, and remains in the lumen. Is intended to be discharged from the lumen.
That is, the biomedical liquid injection device of the present invention can discharge the liquid filled in the syringe in the downstream direction and discharge it from the distal end of the lumen by setting the syringe mounting port to a positive pressure. Moreover, the biomedical solution injection device of the present invention can preferentially inhale gas into the syringe by setting the syringe mounting port to a negative pressure. The gas sucked into the syringe flows again through the flow path for the chemical liquid by setting the syringe mounting port to a positive pressure, and the chemical liquid remaining in the flow path is then discharged from the distal end of the flow path to the outside. Can be extruded.
In the present invention, switching between the positive pressure and the negative pressure at the syringe mounting port can be realized by a simple operation of the syringe mounted on the syringe mounting port. It is possible to improve the usage rate.

The terms in the present invention or terms used in describing the present invention are defined as follows unless otherwise specified.
In the present invention, the outside means the outside of the biological fluid injection tool.
Further, in the present invention, the chemical solution refers to a liquid that can be injected into a living body, and it does not matter whether or not it has any effect on the living body. Therefore, the said chemical | medical solution contains the liquid by which only the adhesion effect for adhere | attaching the desired location of a biological body by mixing one liquid or two liquids or more is anticipated.
In describing the present invention, the terms upstream and downstream are used as appropriate. These terms indicate upstream and downstream in the flow direction of the liquid flowing from the syringe side to the lumen side. The terms upstream and downstream apply to the gas flow direction as appropriate.
In describing the present invention, the terms distal end and proximal end may be used as appropriate. Here, the distal end portion has a predetermined length including the patient-side end portion (distal end) of the biomedical solution injecting device when the medicinal solution is injected into the patient using the biomedical solution injecting device of the present invention. This is the area. Moreover, a proximal end part means the predetermined | prescribed length area | region including the edge part (proximal end) on the opposite side to the patient side of the said medical fluid injection device.
Further, when describing the present invention, when a plunger provided on a syringe is pushed, it means an operation of pushing and mixing the plunger into the syringe body, and when pulling the plunger, the proximal end from the syringe body is called. The operation to pull out the plunger to the side.
Further, regarding the present invention, the negative pressure of the syringe mounting port means that suction pressure is applied from the downstream direction to the upstream direction at the syringe mounting port. Moreover, making a syringe mounting port into a positive pressure means that the pressure which presses with respect to a downstream direction from an upstream is applied in a syringe mounting port.

Hereinafter, a first embodiment and a second embodiment of the present invention will be described with reference to the drawings. In all the drawings, the same components are denoted by the same reference numerals, and redundant description will be appropriately omitted.
In the present embodiment, there are cases where the directions of up, down, left, right, front and back are defined and illustrated as shown. However, this is provided for convenience in order to simply explain the relative relationship of the components, and does not limit the direction during the manufacture or use of the product implementing the present invention.
The various components of the biomedical solution injection device of the present invention do not have to be individually independent, but a plurality of components are formed as one member, and one component is a plurality of members. It is allowed to be formed, a certain component is a part of another component, a part of a certain component overlaps a part of another component, and the like.

<First embodiment>
Below, the structure of the biomedical solution injection tool 100 which is 1st embodiment of this invention is demonstrated using FIGS. 1-5.
FIG. 1 is a cross-sectional view showing a state in which a biological fluid injection tool 100 illustrating a first embodiment of the present invention is cut along the flow direction of the chemical.
FIG. 2 is a perspective view of the connecting portion 24 in the first embodiment of the present invention, and the upper half of the connecting portion 24 in the upper direction of the drawing is omitted.
FIG. 3 is a front view showing an example of the biomedical solution injection tool kit 110 of the present invention in which the syringe 120 is attached to the biomedical solution injection device 100 according to the first embodiment of the present invention.
FIG. 4 is an explanatory diagram for explaining a use state of the biological liquid injector 100 according to the first embodiment of the present invention, and is observed from the front side of the biological drug injector 100. FIG. 4A shows a state in which the operation unit 126 (plunger) provided in the syringe 120 is pressed to discharge the chemical solution filled in the syringe 120. FIG. 4B shows a state in which, after the state shown in FIG. 4A, the operation unit 126 (plunger) is pulled and gas is sucked into the syringe 120 from the gas suction hole 22. In FIG. 4, the plurality of lumens 10 provided in the tubular main body 14 are not shown, and the chemicals remaining in the plurality of lumens 10 are not shown and are collectively shown in one flow path.
FIG. 5A is a top view of the common operation surface 50 in one mode of the operation unit connecting member 144 and shows a mode in which convex portion forming means 51 </ b> A is provided as the guide means 51. FIG. 5B is a side view of another mode of the operation unit connecting member 144 and shows a mode in which the guide means 51 includes a raised portion 52 and a concave portion 53.

  Moreover, the front view of the biomedical-solution injection tool kit 110 of this invention using the biomedical-solution injection tool 114 which is a modification of this embodiment is shown in FIG. In addition, FIG. 7 partially shows a connection part 164 having a gas suction hole 162 with respect to the biomedical liquid injector 114. FIG. 7A is a partial perspective view of the connection portion 164. FIG. 7B is a cross-sectional view taken along the line II in FIG. 7A and shows a state in which gas is being sucked from the gas suction hole 162. FIG.7 (c) is II sectional drawing in Fig.7 (a), Comprising: The inside of the chemical | medical solution flow path 160 shows the state which flows from an upstream direction toward a downstream direction.

  Note that the biomedical solution injection device 100 according to the first embodiment is configured to be bilaterally symmetric about a point that is approximately a half of the direction in which the plurality of syringe mounting ports 18 are arranged. The same applies to the biomedical liquid injection tool 114. The same applies to biomedical liquid injection tool kit 110 using these. In each drawing, a reference numeral may be attached to only one of the two configurations positioned symmetrically as appropriate.

As shown in FIG. 1, the biomedical solution injection device 100 according to the first embodiment of the present invention includes a tubular main body 14 and a connection portion 24.
The tubular body 14 has a plurality of lumens 10 inside. The lumen 10 is a hole through which a chemical solution or gas can flow.
The connecting part 24 is equipped with a plurality of syringes for attaching a plurality of drug solution discharge ports 16 communicating with the plurality of lumens 10 and a plurality of syringes 120 (see FIG. 3) for injecting the drug solution into each of the plurality of lumens 10. A mouth 18 is provided. In the connection portion 24, the plurality of chemical solution discharge ports 16 and the plurality of syringe mounting ports 18 communicate with each other via the chemical solution flow path 20. In addition, the connecting portion 24 includes a gas suction hole 22 that allows the outside to communicate with the plurality of syringe mounting ports 18 to suck gas from the outside toward the syringe mounting port 18 by setting the syringe mounting port 18 to a negative pressure. . The gas suction hole 22 communicates from the suction port 23 to the syringe mounting port 18. Setting the syringe mounting port 18 to a negative pressure can be performed, for example, by performing an operation of sucking a fluid into the syringe 120 by the operation unit 126 (see FIG. 3) of the syringe 120 mounted on the syringe mounting port 18. . More specifically, the syringe mounting port 18 can be set to a negative pressure by pulling the plunger which is the operation unit 126, for example.

The connecting portion 24 is provided with a plurality of regulating means for regulating the flow of fluid.
Specifically, in the connecting portion 24, the chemical flow path 20 includes first regulating means 26 that regulates the flow of the chemical liquid from the lumen 10 side to the syringe mounting port 18 side downstream of the gas suction hole 22. Have. Further, in the connection portion 24, the gas suction hole 22 has second restriction means 28 that restricts the chemical liquid from flowing out from the gas suction hole 22.

  In the first embodiment, specifically, an example in which the tubular main body 14 has two lumens 10 is shown. Correspondingly, the chemical liquid discharge port 16, the syringe mounting port 18, and the chemical liquid flow path 20 are as follows. , Both are provided two by two.

As shown in FIG. 3, the biological drug injection device 100 having the above-described configuration includes a syringe 120 that can be attached to the biological drug injection device 100, thereby configuring a biological drug injection tool kit 110. A biological drug injection tool kit 110 shown in FIG. 3 shows an embodiment of the biological drug injection tool kit of the present invention.
The syringe 120 includes a syringe main body 122 that can contain a chemical solution or gas, an inlet / outlet hole 124, and an operation unit 126 that performs an operation for allowing a fluid to flow into or out of the syringe main body 122 via the inlet / outlet hole 124. ing. The entry / exit hole 124 is a hole that is attached to the syringe attachment port 18 and allows gas or fluid to flow into or out of the syringe body 122.
In the present embodiment, the number of syringes 120 in the biomedical liquid injection tool kit 110 is the same as the number of lumens 10 in the biomedical liquid injection tool 100.
The biomedical liquid injection tool kit 110 in this embodiment enjoys the effects of the biomedical liquid injection tool kit 110.

An example of a use state in which a chemical solution is injected using the biological drug injection tool 100 will be described using the biological drug injection tool kit 110 shown in FIGS. 3 and 4. In this description, the syringe main body 122 is a barrel and the operation unit 126 is a plunger.
First, the syringe main bodies 122 of the two syringes 120 are filled with different chemical solutions, and then the inlet / outlet 124 is inserted into the syringe mounting port 18 and the syringe 120 is mounted on the biological liquid injector 100 (not shown).

Next, the operation part 126 of the syringe 120 is pushed to make the syringe mounting port 18 have a positive pressure. As a result, the chemical liquid filled in the syringe main body 122 flows in the chemical liquid flow path 20 and the lumen 10 in the downstream direction and is discharged from the distal end of the tubular main body 14. At this time, since the second restricting means 28 is provided in the gas suction hole 22, the chemical liquid flowing in the downstream direction in the chemical liquid flow path 20 is restricted from flowing out through the gas suction hole 22. Yes.
As described above, the drug solution is discharged from the biological drug injection tool kit 110, and the drug solution remains in the tubular body 14 and in the drug channel 20 as shown in FIG.
The two lumens 10 (not shown in FIG. 4) are provided inside the tubular main body 14 (see FIG. 1). In the state of FIG. The chemical solution remains in each of the two lumens 10.

Subsequently, as illustrated in FIG. 4A, the operation unit 126 is pulled from the state in which the chemical solution remains so that the syringe mounting port 18 has a negative pressure. At this time, the chemical solution remaining downstream from the first restricting means 26 is restricted from flowing toward the syringe 120 by the first restricting means 26. Therefore, the syringe body 122 is preferentially filled with the gas sucked from the gas suction hole 22 as shown in FIG.
In addition, although the chemical | medical solution which remained upstream from the 1st control means 26 may flow in into the syringe main body 122, the quantity is very slight, and the pushing of the operation part 126 is mentioned so that it may mention later. It can be discharged from the distal end of the tubular body 14 by a pulling action.

  From the state shown in FIG. 4B, the operation unit 126 is pressed again to switch the syringe mounting port 18 to a positive pressure. As a result, the gas filled in the syringe main body 122 flows to the lumen 10 through the chemical liquid flow path 20, and the chemical liquid remaining on the downstream side of the first regulating means 26 is distant from the tubular main body 14. It is pushed out from the end. By performing such a simple operation once or a plurality of times, a state in which no chemical solution remains in the lumen 10 can be obtained (see FIG. 1).

  That is, by discharging a chemical solution filled in the syringe body 122 and then performing a simple operation of pulling and pushing the operation unit 126 once or a plurality of times while the syringe 120 is mounted on the biomedical solution injection device 100. It is possible to use up the chemical remaining in the lumen 10. Thereby, the biomedical solution injection tool 100 can easily improve the usage rate of the chemical solution.

Next, details of the tubular body 14 will be described.
The tubular body 14 includes a plurality of lumens 10. As shown in FIG. 1, the tubular body 14 in the present embodiment shows an example of an integrally molded product having two lumens 10 inserted from the proximal end to the distal end of the tubular body 14 therein. As a modified example, as shown in FIG. 6, intermediate portions of a plurality of catheters 152 having lumens 10 inside thereof are integrated together using a bundling member such as a heat-shrink tape 155 to form a single tubular body 154. Good. The bundling member may be any member that can fix the positional relationship by bringing the two catheters 152 into contact with each other, such as an adhesive tape, an adhesive tape, and an adhesive, in addition to the heat shrinkable tape 155. Good. In FIG. 6, the heat-shrink tape 155 is wound around the whole of the catheter 152 except for the proximal ends of the plurality of catheters 152, and is shrunk by being heated, so that the plurality of catheters 152 are integrated together.

As understood from FIGS. 1 and 3, the distal ends of the two lumens 10 provided in the tubular body 14 are close to each other at the distal end or the distal end of the tubular body 14. Therefore, when the operation part 126 is operated to make the syringe mounting port 18 have a positive pressure and two kinds of chemical solutions are injected into the living body from the distal ends of the two lumens 10, the two kinds of chemical solutions are in the air or Contact is possible on the surface of the living body to be injected. Therefore, the biomedical liquid injection tool kit 110 can inject a plurality of medicinal liquids that exhibit a desired action by mixing them into the living body and cause the action to occur in the living body.
In the tubular body 14 shown in FIGS. 1 and 3, the distal end of one lumen 10 and the distal end of the other lumen are provided at a substantially equal distance from the connection portion 24. One lumen end face and the other lumen end face are provided in the same plane. As a modification that is not shown in the drawings, in the present embodiment, a mode in which a distal end of one lumen 10 and a distal end of another lumen are provided at different distances from the connection portion 24, and a lumen end surface and Other lumen end faces include embodiments oriented in different directions. The phrase “one lumen end surface and the other lumen end surface are oriented in different directions” means that the perpendicular line on one lumen end surface and the perpendicular line on the other lumen end surface are not parallel.

  The length of the tubular main body 14 is not particularly limited, and can be appropriately determined according to the use of the biomedical liquid injector 100. For example, by forming the tubular body 14 into a long shape, it is possible to insert the drug solution into a predetermined affected part such as the digestive tract by inserting the tubular body 14 into a forceps hole or the like provided in the endoscope. is there. The length of the long tubular body 14 is not particularly limited. For example, the length of the long tubular body 14 is in the range of 50 cm or more and 300 cm or less, and further in the range of 100 cm or more and 250 cm or less. It is preferable from the viewpoint of being possible. When the tubular body 14 is scheduled to be inserted into the endoscope, the tubular body 14 is integrally formed with a plurality of lumens 10 inside as shown in FIG. The cross-sectional diameter of 14 can be kept small, which is preferable.

  In general, as the length of the tubular body 14 increases, the amount of chemical remaining in the lumen 10 also increases. Therefore, compared with the aspect provided with the short tubular main body 14, the effect of the present invention is exhibited more advantageously in the biomedical liquid injection device 100 including the long tubular main body 14.

The material which comprises the tubular main body 14 is not specifically limited, It is not ask | required whether it is a hard material or a soft material. Examples of the hard material constituting the tubular main body 14 include metal materials such as stainless steel, or resin materials such as acrylic resin, polypropylene resin, polyethylene terephthalate resin, and polystyrene resin. Moreover, as an example of the soft material which comprises the tubular main body 14, resin materials, such as a soft polyvinyl chloride resin, a polyurethane resin, a silicone resin, can be mentioned, for example.
For example, when the tubular main body 14 is configured in a short shape, and it is planned to inject the chemical liquid directly by applying the biological liquid injection device 100 to a desired affected part of the living body, the chemical liquid injection operation is appropriately performed. From the viewpoint, the tubular body 14 is preferably made of a hard material.
Further, when the tubular body 14 is configured to be elongated and inserted through an endoscope or the like so that the distal end of the tubular body 14 reaches the desired affected part of the living body to perform a liquid injection operation. The tubular body 14 is preferably made of a soft material.

Next, details of the connection unit 24 will be described.
In the present embodiment, the connection unit 24 includes a syringe mounting port 18, a chemical solution discharge port 16, a chemical solution flow path 20, and a gas suction hole 22 as shown in FIG. 1.
The connecting portion 24 constitutes an intermediate region through which the plurality of syringes 120 and the plurality of lumens 10 are inserted. The connection part 24 regulates the flow of the chemical liquid and the gas in a predetermined direction by switching between the positive pressure and the negative pressure of the syringe mounting port 18.
Although the material which comprises the connection part 24 is not specifically limited, From a viewpoint of protecting the 1st control means 26 provided in the inside, the 2nd control means 28, the chemical | medical solution flow path 20, etc., it is comprised from a hard material. Is preferred. Since the example of the said hard material is the same as that of the hard material demonstrated in the tubular main body 14 mentioned above, the overlapping description is abbreviate | omitted.

  In this embodiment, the connection part 24 has shown the aspect which equips with the several syringe mounting opening 18 and the some chemical | medical solution discharge port 16 integrally. However, the connecting portion of the present invention is not limited to the above. For example, as in the biomedical liquid injection tool 114 illustrated in FIG. 6, an assembly including a plurality of connection parts 164 is provided by providing a plurality of connection parts 164 including one syringe mounting port 158 and one chemical liquid discharge port 156. It is also possible to configure a connection part as

The connection part 24 in the present embodiment includes a first member 34 having a plurality of chemical solution discharge ports 16, a second member 36 having a plurality of syringe mounting ports 18, and the first member 34 and the second member 36. The intermediate member 38 is positioned.
The 1st member 34, the 2nd member 36, or the intermediate member 38 has the recessed part (The enlarged diameter part 40 shown in FIG. 1, the fitting part 42) opened in the mutually opposing end surface. The 1st control means 26 or the 2nd control means 28 is provided in the said recessed part.

  The 1st member 34, the 2nd member 36, and the intermediate member 38 are comprised as an independent member, and comprise the one connection part 24 by joining these three members. Means for realizing the bonding is not particularly limited. For example, chemical bonding using an adhesive or the like, physical bonding by fitting the concavo-convex structure to each other, or the chemical bonding and the physical bonding. The combination of joining etc. can be mentioned. In the present embodiment, the concave and convex structures of each other are fitted to each other, and the connecting portion 24 is integrally formed by joining three members. In addition, the connection portion 24 is provided with a screw hole 141 that penetrates the first member 34 and the intermediate member 38 and a screw hole 142 that penetrates the second member 36 and the intermediate member 38 in order to maintain the joined state. It is screwed. In addition, in FIG. 1 to FIG. 4, the screws used for the screwing are not shown.

  By configuring the connecting portion 24 with the three members described above, it is easy to stably install the check valve 104 inside the connecting portion 24. That is, by connecting the one member and the other member with the check valve 104 fitted into the recess and facing the opposite end faces, the connection portion of the check valve 104 can be connected without dropping. 24 can be built in.

A specific example in which the check valve 104 as the first restricting means 26 is installed in the recess will be described.
In the intermediate region of the chemical liquid flow channel 20 in the present embodiment, a small-diameter region 41a and a small-diameter region 41b and an enlarged diameter portion 40 having a relatively large diameter are provided. The enlarged diameter portion 40 is sandwiched between the small diameter region 41a and the small diameter region 41b from the upstream and downstream directions. The enlarged diameter portion 40 corresponds to a concave portion in which the first regulating means 26 is installed. The enlarged diameter portion 40 in the present embodiment is provided in the first member 34 and is open at an end surface of the first member 34 facing the intermediate member 38. Therefore, before joining the first member 34 and the intermediate member 38, the check valve 104 which is the first restricting means 26 is fitted into the enlarged diameter portion 40, and then the first member 34 and the intermediate member 38 are joined. By doing so, the check valve 104 can be stably held inside the connecting portion 24.
A small-diameter region 41 a located on the upstream side with respect to the enlarged diameter portion 40 is provided in the intermediate member 38. By joining the first member 34 and the intermediate member 38, the small-diameter region 41 a, the check valve 104 fitted in the enlarged-diameter portion 40, and the small-diameter region 41 b communicate with each other. An intermediate region is constructed.

  The enlarged diameter portion 40 is formed in a cylindrical shape, and is fitted into the enlarged diameter portion 40 so that the open / close end 140 of the check valve 104 faces the downstream side. That is, the check valve 104 is fitted in a direction that regulates the flow of the chemical liquid from the downstream side to the upstream side. A stepped portion 138 that gently slopes downstream is provided between the enlarged diameter portion 40 and the narrow diameter region 41b on the downstream side. On the other hand, the open / close end 140 of the check valve 104 is formed flat and is arranged in a direction in which the open / close end 140 intersects perpendicularly with respect to the flow path direction of the chemical liquid flow path 20. Therefore, a space is ensured between the stepped portion 138 and the open / close end 140 of the check valve 104, whereby the opening / closing operation of the open / close end 140 is smooth.

  A skirt portion 134 extending outward in the radial direction is provided at the end of the check valve 104 opposite to the open / close end 140. A stepped portion 130 and a stepped portion 132 that are continuous in the circumferential direction are provided on the outer surface of the skirt portion 134. A space corresponding to the shape of the skirt portion 134 of the check valve 104 fitted in the enlarged diameter portion 40 is formed on the upstream side of the enlarged diameter portion 40. The space can be constituted by a gap provided between the first member 34 and the intermediate member 38, for example. Steps corresponding to the stepped portion 130 and the stepped portion 132 are provided on the wall surface constituting the space (in the present embodiment, a predetermined portion of the first member 34). The skirt portion 134 is fitted into the space, and the stepped portion 130 and the stepped portion 132 are locked to the corresponding stepped portion, and the fitting position of the check valve 104 is fixed. In other words, the skirt portion 134 is sandwiched between the intermediate member 38 and the second member 36 and the insertion position thereof is fixed.

  The first restricting means 26 allows the chemical liquid and gas to flow from the upstream side to the downstream side, and restricts the chemical liquid and gas from flowing from the downstream side to the upstream side. Regulating here includes not only an aspect of completely preventing the flow of the chemical solution and the gas but also an aspect of suppressing the flow within the scope of achieving the intended problem of the present invention.

  The first regulating means 26 is not particularly limited as long as it is a means that can regulate the flow of the chemical solution and the gas as described above, and various means can be adopted. In this embodiment, an example using a check valve 104 is shown. More specifically, a so-called duckbill valve is used that opens when pressure is applied to the inner surface and closes when pressure is applied to the outer surface. The duckbill valve is provided with a concave groove 136 extending in the flow path direction so that the valve can be opened and closed smoothly. By forming the concave groove 136, the center of the width of the valve becomes thin and easily deforms. Therefore, the valve body opens well even at a weak discharge pressure, and the valve body closes well by a weak pressure on the outer surface. The concave groove 136 may be provided on either the inner side or the outer side of the valve, but by providing it on the inner side, the flow path in the valve body can be increased.

  As the first regulating means 26 other than the check valve in the present embodiment, an orifice is provided in the chemical liquid flow path 20 to suppress the flow of the chemical liquid from the downstream side to the upstream side rather than the flow of the chemical liquid from the upstream side to the downstream side. Means are mentioned. Further, as a modified example of the different first restricting means 26, an openable / closable lid member that shields the flow path may be automatically or manually opened and closed at a desired timing. However, these descriptions do not limit the first regulating means in the present invention.

  The first restricting means 26 allows the chemical solution filled in the syringe to flow in the downstream direction when the syringe mounting port 18 is set to a positive pressure, and the first restricting means 26 when the syringe mounting port 18 is set to a negative pressure. It restricts that the chemical | medical solution which remains downstream from 26 flows in an upstream direction.

  The mode of installation of the check valve 104 that is the first restricting means 26 can be changed by changing the mode of the connecting portion 24. For example, a biological drug injection tool 114 that is a modification of the present embodiment shown in FIG. 6 is provided with a plurality of cylindrical connection portions 164. The plurality of connection portions 164 have a one-to-one relationship with the plurality of syringes 120. One connection portion 164 is provided with one syringe mounting port 158 and one chemical solution discharge port 156. Inside the cylinder, there is provided a chemical flow channel 160 through which the syringe mounting port 158 and the chemical discharge port 156 are inserted. The chemical flow channel 160 is an intermediate portion of the chemical flow channel 160 and is downstream of a gas suction hole 162 described later. One regulating means 166 is provided. For example, a check valve such as a duckbill valve can be used as the chemical liquid flow path 160 and can be fitted into the chemical liquid flow path 160. The check valve inserted into the chemical flow path 160 may be fixed at the inserted position by an adhesive or other means as necessary. In addition, the description regarding the 1st control means 26 in this specification is applied to the 1st control means 166 suitably except the aspect of installation.

Next, a specific example in which the check valve 104 which is the second regulating means 28 in the concave portion is installed will be described.
A fitting portion 42 for fitting and fixing the check valve 104 is provided in an intermediate region of the gas suction hole 162 in the present embodiment. The fitting portion 42 is a cylindrical recess that opens on the end surface of the intermediate member 38 on the second member 36 side. The check valve 104 serving as the second restricting means 28 is previously covered with a cover member 44 and the outer shape thereof is adjusted to a cylindrical shape. The outer shape of the check valve 104 covered with the cover member 44 is substantially equal to the shape of the cylindrical recess. Therefore, the check valve 104 covered with the cover member 44 can be smoothly fitted into the fitting portion 42 which is a cylindrical recess.

  The check valve 104 serving as the second restricting means 28 is fitted into the fitting portion 42 so that the open / close end 140 faces the second member 36. In other words, the check valve 104 is fitted in a posture that restricts the flow of the chemical from the syringe mounting port 18 side to the gas suction hole 22. A gas suction path 32 is provided at a position of the second member 36 facing the fitting portion 42, and the gas suction path 32 in the intermediate member 38 and the gas suction path 32 in the second member 36 have a check valve 104. Communicated through. The open / close end 140 of the check valve 104, which is the second regulating means 28, faces the gas suction path 32 in the second member 36.

  The second restricting means 28 is provided at an arbitrary position of the gas suction hole 22. The second restricting means 28 allows the gas to flow from the intake port 23 side to the syringe mounting port 18 side, and restricts the chemical liquid or the gas from flowing from the syringe mounting port 18 side to the intake port 23 side. Here, “regulating” is the same as the contents described for the first regulating means 26. By providing the second regulating means 28, the chemical liquid is prevented from flowing out from the air inlet 23.

  The second regulating means 28 is not particularly limited as long as it is a means capable of regulating the flow of the chemical solution and the gas as described above, and various means can be adopted. In the present embodiment, an example using a check valve 104 is shown as in the case of the first regulating means 26. The example of the check valve 104 and the other second restricting means 28 is appropriately described with respect to the first restricting means 26, and therefore, the same description is omitted here. In the present embodiment, the first regulating means 26 and the second regulating means 28 use the same check valve 104. However, within the applicable range, the first regulating means 26, the second regulating means 28, The configuration may be changed as appropriate.

The mode of the second restricting means 28 can be changed by changing the mode of the connecting portion 24. For example,
The biomedical liquid injection tool 114 shown in FIG. 6 is provided with second restricting means 168 that is also used as the gas suction hole 162 formed in the cylindrical connecting portion 164.
The gas suction hole 162 is a cut that obliquely cuts the surface of the cylindrical connecting portion 164 from the downstream side toward the upstream side and penetrates from the surface to the chemical liquid flow channel 160. The notch includes an external opening 174 that opens to the outside and an internal opening 176 that opens to the side of the chemical liquid flow channel 160. The opening area of the external opening 174 is configured to be larger than the opening area of the internal opening 176.
From the viewpoint of facilitating the formation of the notches, the connecting portion 164 may be composed of a soft resin member.

The second restricting means 168 that is also used as the gas suction hole 162 will be described with reference to FIG. As shown in FIGS. 7A to 7C, the gas suction hole 162 is a V-shaped cut that penetrates the chemical liquid flow channel 160 from the surface of the cylindrical connection portion 164. FIG. 7B and FIG. 7C show the II cross section cut at the position that bisects the V shape through the vertex of the V shape. In the gas suction hole 162 that is a V-shaped cut, the cross-sectional area of the channel continuously decreases from the outside toward the chemical channel 160. On the downstream side of the internal opening 176, a tongue portion 178 having a sharp tip is formed.
When the syringe mounting port 158 (not shown) is at a positive pressure, as shown in FIG. 7B, the chemical liquid or gas flows through the chemical liquid flow path 160 from the upstream side toward the downstream side. An arrow 172 schematically shows the flow of the chemical solution or gas. At this time, the tongue 178 is pushed outward by receiving the internal pressure, and the internal opening 176 is closed. That is, the gas suction hole 162 is closed.
Further, when the syringe mounting port 158 (not shown) has a negative pressure, the back flow of the chemical liquid in the chemical liquid flow path 160 is regulated by the first regulating means 166 (see FIG. 6) provided on the downstream side of the gas suction hole 162. Therefore, as shown in FIG. 7C, the gas suction hole 162 is opened, and the gas is sucked toward the syringe mounting port 158. An arrow 170 schematically shows the flow of the gas sucked from the gas suction hole 162.
When the syringe mounting port 158 is at a positive pressure, the gas suction hole 162 restricts the chemical solution or gas from flowing out from the chemical channel 160 through the gas suction port 162, and when the syringe mounting port 158 is at a negative pressure. Also, it acts as a check valve that allows gas inhalation from the outside.

  Next, the gas suction hole 22 will be described. The gas suction hole 22 communicates the outside with the plurality of syringe mounting ports 18. Specifically, the gas suction hole 22 in the present embodiment communicates the suction port 23 provided in the connection portion 24 and the plurality of syringe mounting ports 18. By setting the syringe mounting port 18 to a negative pressure, the gas is sucked from the outside toward the syringe mounting port 18 through the suction port 23. The inhaled gas can be filled into the syringe main body 122 of the syringe 120 attached to the syringe attachment port 18. A second regulating means 28 is provided at an arbitrary position of the gas suction hole 22.

In the biomedical liquid injection device 100 according to this embodiment, the gas suction hole 22 has a plurality of gas suction passages 32 communicating with the plurality of syringe mounting ports 18 respectively. A second restricting means 28 is provided in each of the plurality of gas suction paths 32.
According to such a configuration, the plurality of chemical liquids that have flowed into the connection portion 24 from the plurality of syringe mounting ports 18 do not come into contact with each other in the gas suction hole 22.

The gas suction hole 22 has an intake port 23 through which a plurality of gas suction passages 32 communicate with each other and sucks gas from the outside. In the present embodiment, the opening area of the intake port 23 is equal to or larger than the sum of the opening areas at the end portions on the intake port 23 side in the plurality of gas suction paths 32. In FIG. 1, an opening width A indicated by a tall double-ended arrow indicates the opening width of the intake port 23, and an opening width B indicated by a short-extended double-ended arrow indicates the opening width of the gas suction path 32. In the present embodiment, the opening width A is configured to be at least twice the opening width B.
More specifically, the gas suction hole 22 has one intake port 23 which is a large opening and communicates with a plurality of gas suction paths 32 together. The gas suction hole 22 has a large-diameter path 22A extending as a single flow path to the ends of the plurality of gas suction paths 32 and a small-diameter gas branched thereafter, while maintaining the opening diameter of the suction port 23. A plurality of suction paths 32 (small-diameter paths 22B) are provided.
As understood from FIG. 2, when the connection portion 24 is observed from the direction in which the openings at the ends of the plurality of gas suction paths 32 on the inlet 23 side and the suction openings 23 overlap in the front-rear direction, the plurality of gas suction paths 32. The opening at the end of this is included in the air inlet 23.

  In the present embodiment, the gas suction path 32 is a gas flow path through which the gas flows from the suction port 23 toward the syringe mounting port 18. The gas suction hole 22 may include a single gas suction path 32 that continues from one suction port 23 and a plurality of gas suction paths 32 that branch from the single gas suction path 32. Moreover, as another aspect which abbreviate | omits illustration, a gas suction hole may be comprised from the several gas suction path from which the path from an inlet port to a syringe mounting port becomes independent, respectively. In such another aspect, it has a plurality of intake ports communicating with each of a plurality of independent gas suction paths.

  By providing the gas suction hole 22 with a common large-diameter passage 22A extending from the suction opening 23, which is a large opening, the gas suction is made smooth. Further, the flow paths of the plurality of gas suction paths 32 (small diameter paths 22B) can be shortened by the amount of the large diameter path 22A provided in the gas suction hole 22, and the fluidity of the gas in the gas suction hole 22 is improved. .

  As described above, the gas suction hole 22 has the suction port 23 for sucking gas from the outside. As shown in FIG. 1, the air inlet 23 opens toward the distal end side of the biomedical liquid injector 100.

In view of the fact that the syringe mounting port 18 is provided closer to the proximal end side than the intake port 23 in the present embodiment, the gas sucked from the intake port 23 opened to the distal end side is generally the distal end side. Can flow smoothly toward the proximal end side. That is, the gas taken in from the intake port 23 once flows in the connection portion 24 to the distal end side, and then greatly changes the flow direction to flow to the proximal end side. The conversion is not forced by design.
Further, when operating the syringe 120 attached to the syringe attachment port 18, the operator's hand is prevented from coming into contact with the intake port 23, and from the viewpoint of preventing erroneous operation, the intake port 23 is located on the distal end side. It is preferable to be provided.

In the present embodiment, as described above, the gas suction hole 22 has a plurality of gas suction passages 32 communicating with the plurality of syringe mounting ports 18. The plurality of gas suction paths 32 and the plurality of chemical liquid channels 20 are in communication with each other, the end region on the syringe mounting port 18 side of the plurality of gas suction paths 32 and the syringe mounting of the plurality of chemical liquid channels 20. A plurality of overlapping regions 30 where the end regions on the side of the mouth 18 meet each other are provided. In the overlapping region 30, the chemical liquid flow path 20 and the gas suction path 32 share one flow path.
Here, the end region refers to a region including an end connected to the syringe mounting port 18.

As shown in FIG. 1, the plurality of gas suction passages 32 extend in the depth direction from the opening of the suction port 23, bend in the direction of the corresponding chemical liquid flow channel 20 in the middle portion of the gas suction hole 22, and It reaches the middle part of the flow path 20 and joins and communicates with the chemical liquid flow path 20. The depth direction is a direction from the intake port 23 toward the gas intake hole 22 when the opening of the intake port 23 is the front side and the gas intake hole 22 extending from the intake port 23 is the back direction. . More specifically, the gas suction path 32 in the present embodiment is directed in the opening depth direction of the suction port 23, extends in parallel with the chemical liquid flow path 20, and bends at a substantially right angle at the intermediate portion of the gas suction hole 22. , It extends toward the corresponding chemical liquid flow path 20, and merges with and communicates with the chemical liquid flow path 20.
From the merged point to the syringe mounting port 18, the chemical liquid flow path 20 and the gas suction path 32 overlap, and an overlapping region 30 is configured.

  According to the biomedical liquid injection device 100 having the overlapping region 30, when the gas is sucked from the gas suction hole 22, not only the syringe 120 mounted in the syringe mounting port 18 but also the end region of the chemical flow channel 20 is provided. Can be filled with the gas. By setting the syringe mounting port 18 to a negative pressure in this state, the gas filled in the syringe 120 can smoothly flow into the chemical liquid channel 20.

Although not shown in the drawings, the biological liquid injector 100 according to the present embodiment is provided with a sterilization filter in the gas suction hole 22, and the gas sucked from the outside passes through the sterilization filter toward the syringe mounting port 18. May be configured to flow in. Thus, the sterilized gas can be sucked into the syringe 120, passed through the lumen 10, and discharged into the living body, which is preferable in terms of hygiene.
The position at which the sterilization filter is provided in the gas suction hole 22 is not particularly limited. For example, by disposing the sterilization filter in the above-described large-diameter path 22A, the gas sucked from the intake port 23 is once divided in the small-diameter path 22B. Can be sterilized. In addition, by disposing the sterilization filter in the gas suction hole 22 closer to the intake port 23 than the second restricting means 28, it is possible to prevent the sterilization filter and the chemical solution from contacting each other.
The sterilization filter is not particularly limited as long as it can appropriately remove dust and various germs present in the outside air. For example, although the filter provided in the sterilization filter is a membrane filter, a general filter such as a general screen type, a depth type, or an anisotropic type can be appropriately selected and used.

  In the biological drug injection device 100 having the overlapping region 30, the first regulating means 26 is provided on the downstream side of the overlapping region 30 in the plurality of drug solution flow paths 20. For this reason, when the syringe mounting port 18 is set to a negative pressure, the gas sucked through the gas suction hole 22 passes through the overlapping region 30 from the downstream side to the upstream side without being regulated by the first regulating means 26. Can do.

A syringe mounting port 18 is provided at the upstream end of the overlapping region 30.
The syringe mounting port 18 is continuous with the chemical liquid channel 20 while opening the tip region of the inlet / outlet 124 of the syringe 120 to be mounted so that it can be directly or indirectly inserted. The chemical liquid channel 20 communicates the syringe mounting port 18 and the chemical liquid discharge port 16. A chemical solution discharge port 16 is provided at the distal end of the chemical solution flow path 20, and the lumen 10 is continuous with the chemical solution discharge port 16. In the present embodiment, the connection end 12 of the tubular main body 14 having the lumen 10 is directly connected to the chemical solution discharge port 16 and fixed with an adhesive or the like. This embodiment includes the aspect which connects the connection end 12 and the chemical | medical solution discharge port 16 as a modification using the connector which is not illustrated. As another modified example, there is included a mode in which at least a partial region of the connection portion 24 including the chemical liquid discharge port 16 and the connection end 12 or the entire tubular body 14 having the connection end 12 are integrally formed.

Next, the biomedical solution injection tool kit 110 will be described. As described above, the biological drug injection tool kit 110 includes the biological drug injection tool 100 and the syringe 120.
The syringe 120 can be configured, for example, by including a cylindrical barrel as the syringe body 122, a plunger as the operation unit 126, and a nozzle provided at the tip of the barrel as the inlet / outlet 124. The distal end of the plunger has, for example, a cylindrical piston portion 126A that fits inside the barrel, and the syringe 120 can be operated by pushing and pulling the plunger against the barrel.
The biomedical solution injection tool kit 110 can include a syringe 120 that is used exclusively for the biomedical solution injection device 100. Alternatively, the biomedical solution injection tool kit 110 may include a commercially available syringe 120 and a biomedical solution injection device 100 in which the syringe mounting port 18 applicable to the inlet / outlet 124 of the commercially available syringe 120 is designed. it can. The syringe 120 may be attached to the biomedical solution injection tool 100 by inserting and fitting the inlet / outlet holes 124 directly into the syringe attachment port 18. Alternatively, the syringe 120 may be mounted on the biomedical liquid injector 100 by appropriately using a connecting member that connects the syringe mounting port 18 and the inlet / outlet 124 so as to communicate with each other.

Among the plurality of syringes 120, at least one syringe 120 is provided with identification means 153 for enabling identification of the one syringe 120 and the other syringe 120 (see FIG. 3). The identification unit 153 may be any mode as long as it can identify the one syringe 120 when the plurality of syringes 120 are visually observed. Specifically, an identification unit 153 that is a display unit with a numeral “1” is provided on the outer surface of the syringe body 122 of one syringe 120 of the two syringes 120 in the present embodiment. ing. As other identification means 153 not shown, coloring means for coloring an arbitrary portion of one syringe 120 to a color different from that of the other syringe 120, and an arbitrary portion of one syringe 120 different from that of the other syringe 120 Examples include shape deforming means formed into a shape. Of course, the identification means 153 may be provided in two or more of the plurality of syringes 120.
By providing the identification unit 153, it is possible to indirectly identify that one syringe 120 is filled with a predetermined chemical solution by checking the identification unit 153.

  In the present embodiment, the two syringes 120 attached to the biological drug injection device 100 are connected to each other and fixed to each other by a syringe body connecting member 148 (see FIG. 3). In the present embodiment, the syringe body connecting member 148 has as many syringe body gripping portions 150 as the number of syringes 120 provided with fitting recesses 150 </ b> A that fit into the side surfaces of the cylindrical syringe body 122. By connecting the plurality of syringes 120 with the syringe body connecting member 148, they can be handled integrally, and the handleability of the biomedical liquid injector kit 110 can be improved.

The biomedical solution injection tool kit 110 according to the present embodiment includes an operation part connecting member 144 having a plurality of operation part gripping parts 146 for gripping the plurality of operation parts 126. The operation unit connecting member 144 has a common operation surface 50 for simultaneously pressing and operating the plurality of operation units 126.
Specifically, for example, the operation unit 126 provided in each of the two syringes 120 is held by two operation unit holding units 146, thereby connecting the two operation units.
In the present embodiment, the operation unit connecting member 144 has as many operation unit gripping units 146 as the number of syringes 120 provided with fitting recesses 146 </ b> A that fit into the proximal end of the operation unit 126. The plurality of operation portion gripping portions 146 are linked by a plate-like connecting portion 146B. A plurality of operation portion gripping portions 146 are provided on one surface of the plate-like connecting portion 146B, and a common operation surface 50 is provided on the other surface. In the present embodiment, the common operation surface 50 is a push surface for the operator of the biological drug injection tool kit 110 to press a plurality of operation units 126 simultaneously in the discharge direction of the syringe 120 with a finger or the like, for example. Yes. By connecting the plurality of operation units 126 to each other by the operation unit connecting member 144, the plurality of operation units 126 can be operated simultaneously by a common operation in the biological fluid injection tool kit 110. Thereby, the operability of the biomedical solution injection tool 100 can be improved, and different medicinal solutions filled in the plurality of syringes 120 can be simultaneously injected into the living body. However, the above description does not exclude that the plurality of syringes 120 are individually operated without using the operation unit connecting member 144 in the biological fluid injection tool kit 110 according to the present embodiment.

  The common operation surface 50 in the present embodiment is provided with guide means 51 that indicates a region to be pressed on the common operation surface 50. The region to be pressed is a region recommended for the operator to touch the common operation surface 50 with his / her finger when operating the biomedical liquid injector 100. The operator's finger is guided consciously or unconsciously to an area where it is recommended to press the finger when operating the common operation surface 50. The guide means 51 includes both an aspect in which the place where the guide means 51 is provided is shown as an area to be pressed, or an aspect in which an area different from the area where the guide means 51 is provided is shown as an area to be pressed.

Although the specific aspect of the guide means 51 is not specifically limited, For example, as shown to FIG. 3 and FIG. 5 (a), the guide means 51 is a 1 or several convex part formation means which protrudes slightly in the common operation surface 50, for example. It may be 51A. The convex portion forming means 51A indicates that the region where the convex portion forming means 51A is provided is the region to be pressed. For example, the convex portion forming means 51A can be configured by arranging linear protrusions extending in one direction. The protrusions of the plurality of filaments can also exhibit an anti-slip action when the operator touches the finger. In other words, the convex portion forming means 51A is a guide means 51 for allowing the operator to recognize the fact that the convex portion forming means 51A should be pushed with a finger when the operator recognizes it visually or tactilely. It is.
As another mode of the guiding means 51, the common operation surface 50 is relatively hard to be touched by the operator's finger, a non-contact area (area other than the area to be pressed), and an easily contact area (area to be pressed), It is also possible to adopt means for discriminating these according to physical shapes. For example, as shown in FIG. 5B, the guide means 51 may be configured by a raised portion 52 having one or a plurality of peaks that are non-contact areas and a concave portion 53 that is a contact area. The recess 53 can be configured as a gentle depression to such an extent that the belly of an adult finger (for example, thumb or index finger) fits. The raised portion 52 and the recessed portion 53 are smoothly connected to each other so that even if the operator tries to press the finger (thumb) against the raised portion 52, the finger naturally slides toward the recessed portion 53. Be guided to. That is, the raised portion 52 and the recessed portion 53 are guide means 51 for guiding the operator's finger unconsciously from the non-contact area toward the contact area.

In a top view of the common operation surface 50, the guide unit 51 can be provided in a region overlapping with the operation unit 126 of one syringe 120 of the plurality of syringes 120 or a region adjacent to the operation unit 126. FIGS. 5A and 5C show an example in which the guide unit 51 is provided in a region overlapping with the operation unit 126 of one syringe 120 out of the plurality of syringes 120.
According to this aspect, when it is recommended that the operation unit 126 of one syringe 120 be pressed more strongly than the operation unit 126 of another syringe 120, the one syringe 120 is selectively pressed strongly in a common operation. It is possible to easily prompt the operator to perform the operation.
For example, in a plurality of chemical solutions that are scheduled to be filled in a plurality of syringes, the following advantages are obtained when the viscosity of one chemical solution is higher than the viscosity of another chemical solution. That is, even when the gas filled in the syringe main body 122 is caused to flow toward the lumen 10 through the gas suction path 32 and the chemical liquid remaining in the lumen 10 is discharged, the high-viscosity chemical liquid and the low-viscosity chemical liquid are evenly lumened. 10 can be discharged. Specifically, an area to be pressed may be indicated by using the guide unit 51 so as to push the common operation surface 50 biased toward the one syringe 120 that has discharged the high-viscosity chemical. Thereby, when the common operation surface 50 is pressed and the plurality of operation units 126 are simultaneously pressed, the one syringe 120 is pushed in slightly more than the other syringe 120. Therefore, the high-viscosity and low fluidity chemical solution remaining in the lumen 10 can be discharged using gas evenly with the low-viscosity and high fluidity chemical solution remaining in the other lumen 10. Therefore, in such a case, it is preferable to selectively provide the guide unit 51 in a region overlapping or adjacent to the operation unit 126 of the single syringe 120 in top view so as to recommend that the single syringe 120 be strongly pressed.

  As described above, when the chemicals filled in the two syringes 120 have different viscosities, the guide means 51 is provided so as to press the common operation surface 50 biased toward the one syringe 120 from which the high-viscosity chemical is discharged. Good. Therefore, the operation unit connecting member 144 is configured such that the direction in which the operation unit connecting member 144 is attached to the operation unit 126 of the plurality of syringes 120 is always constant, or the operation unit connecting member 144 is correctly oriented with respect to the operation unit 126. It is preferable to have the 2nd identification means for attaching to. The second identification unit operates the operation unit connecting member 144 so that the region to be pressed indicated by the guide unit 51 provided on the common operation surface 50 is on the side of the one syringe 120 from which the high-viscosity chemical solution is discharged. It is means for instructing the orientation when attaching to the portion 126. As described above, one syringe 120 of the plurality of syringes 120 has an identification unit 153 for identifying the one syringe 120 and the other syringe 120. In other words, the second identification means indicates that either one of the syringe 120 indicated by the identification means 153 or the other syringe 120 (syringe filled with a high-viscosity chemical solution) is an area to be pressed indicated by the guide means 51. It is a means for making it recognize.

  In the biomedical solution infusion tool kit 110 using the biomedical solution infusion device 100, if there is a difference in the viscosity of the medicinal solution filled in each of the plurality of syringes 120, the means described below is further added to discharge the medicinal solution. The speed may be adjustable.

In a plurality of chemical solutions that are scheduled to be filled in a plurality of syringes, there are the following problems when the viscosity of one chemical solution is lower than the viscosity of another chemical solution. That is, when the plungers in a plurality of syringes are pushed with a substantially uniform force, the discharge speed of the one chemical liquid may be faster than the discharge speeds of the other chemical liquids. As a result, before the discharge of the other chemical solution is completed, the discharge of the one chemical solution is completed, and there is a possibility that desired chemical solution mixing may not be realized in the affected area of the living body.
In response to the above problems, friction means (hereinafter also referred to as first means) that can increase the pushing force of the plunger in one or more of the plurality of syringes in the biomedical solution injection tool kit 110 is provided. Can do. As an example of the first means, for example, a protrusion provided on the inner surface of the barrel of the syringe and a piston portion provided at the distal end of the plunger can be exemplified, but the invention is not limited thereto. The protrusion can be formed, for example, as a convex portion that is continuous or intermittently continuous with the inner surface of the barrel along the sliding direction of the piston portion. The shape and dimensions of the protrusion can be appropriately determined within a range that allows the piston portion to slide in the barrel.

  Alternatively, in one or two or more chemical liquid channels among the plurality of chemical liquid channels, flow resistance increasing means (hereinafter also referred to as second means) for increasing the flow resistance of the chemical liquid flowing in the chemical liquid channel inside. ) May be provided. As an example of the second means, for example, a reduced diameter portion that suppresses the fluidity of the chemical liquid at an arbitrary position in the chemical liquid flow path may be provided, but is not limited thereto.

The biomedical solution injection tool kit of the present invention can comprise the first means or the second means described above. Moreover, the biomedical solution injection tool of this invention can be equipped with the 2nd means mentioned above. By filling a syringe corresponding to the chemical liquid flow path including the first means or the chemical liquid flow path including the second means with a relatively low viscosity, the discharge speed of the plurality of chemical liquids is adjusted, and the plurality of chemical liquids are adjusted. It is possible to make the timing to use up at the same time or at a later time.
In the biomedical solution injection tool kit including the first means or the second means, the use of the operation unit connecting member 144 described above is optional.

  The first embodiment and modifications of the present invention have been described above. The present invention is not limited to the above-described embodiment, and includes various modifications and improvements as long as the object of the present invention is achieved.

The above embodiment includes the following technical idea.
(1) a tubular body having a plurality of lumens therein;
A plurality of chemical solution discharge ports communicating with each of the plurality of lumens, a plurality of syringe mounting ports for mounting a plurality of syringes for injecting a chemical solution to each of the plurality of lumens, a plurality of the chemical solution discharge ports, and the plurality of the above-mentioned lumens Gas is sucked from the outside toward the syringe mounting port by connecting a plurality of chemical liquid flow channels communicating with the syringe mounting port, and connecting the outside and the plurality of syringe mounting ports with a negative pressure. And a connecting portion having a gas suction hole for,
The connecting portion has a first restricting means for restricting the chemical liquid from flowing out from the lumen side to the syringe mounting port side on the downstream side of the gas suction hole,
The biological fluid injection tool, wherein the gas suction hole has a second restricting means for restricting the chemical solution from flowing out of the gas suction hole.
(2) The gas suction hole has a plurality of gas suction passages communicating with the plurality of syringe mounting ports, and the plurality of gas suction passages and the plurality of chemical liquid flow passages communicate with each other. ,
The above (1) having a plurality of overlapping regions in which the end region on the syringe mounting port side of the plurality of gas suction paths and the end region on the syringe mounting port side of the plurality of chemical liquid flow paths respectively merge. ) The biomedical solution infusion device described in 1).
(3) The biological fluid injection device according to (2), wherein the plurality of chemical fluid flow paths have the first regulating means on the downstream side of the overlapping region.
(4) The gas suction hole has a plurality of gas suction passages communicating with the plurality of syringe mounting ports,
The biomedical liquid injection tool according to any one of (1) to (3), wherein the second restriction unit is provided in each of the plurality of gas suction paths.
(5) The gas suction hole has an intake port through which a plurality of the gas suction paths communicate together and sucks gas from the outside,
The biomedical solution injecting device according to (4), wherein an opening area of the intake port is equal to or greater than a sum of opening areas of end portions on the intake port side in the plurality of gas suction paths.
(6) The gas suction hole has an intake port for sucking gas from the outside,
The biological fluid injection device according to any one of (1) to (5), wherein the intake port is open toward a distal end side of the biological fluid injection device.
(7) The connecting portion is a first member having a plurality of the chemical solution discharge ports, a second member having a plurality of the syringe mounting ports, and an intermediate position between the first member and the second member. And having a member
The first member, the second member, or the intermediate member has a recess that opens at end surfaces facing each other,
The biological fluid injection device according to any one of (1) to (6), wherein the first restriction means or the second restriction means is provided in the recess.
(8) Any of the above (1) to (7), wherein a sterilization filter is provided in the gas suction hole, and gas sucked from the outside passes through the sterilization filter and flows toward the syringe mounting port. The biomedical solution injector according to claim 1.
(9) The biological fluid injection device according to any one of (1) to (8) above, and
A syringe body capable of containing a chemical solution or gas, an inlet / outlet through which the gas or fluid flows into or out of the syringe body attached to the syringe mounting port, and fluid to the syringe body through the inlet / outlet A biomedical solution injection tool kit comprising a plurality of syringes having an operation unit for performing an operation for inflow or outflow.
(10) having an operation unit connecting member having a plurality of operation unit gripping units for gripping the plurality of operation units and having a common operation surface for simultaneously pressing and operating the plurality of operation units;
The biological fluid injection tool kit according to (9), wherein the common operation surface is provided with guide means that indicates a region to be pushed on the common operation surface.
(11) In the top view of the common operation surface, the operation portion of one of the plurality of syringes is provided in a region overlapping with the guide unit or a region adjacent to the guide unit. (10) The biomedical solution injection tool kit according to (10).

DESCRIPTION OF SYMBOLS 10 ... Lumen 12 ... Connection end 14 ... Tubular main body 16 ... Chemical solution discharge port 18 ... Syringe installation port 20 ... Chemical solution flow path 22 ... Gas suction hole 22A ... Large Path 22B ... Small path 23 ... Inlet 24 ... Connector 26 ... First regulating means 28 ... Second regulating means 30 ... Overlapping region 32 ... Gas suction path 34. ··· First member 36 ··· Second member 38 ··· Intermediate member 40 · · · Large diameter portion 41a · · · Small diameter region 41b · · · Small diameter region 42 ··· Fitting portion 44 ··· Cover member 50 ... Common operation surface 51 ... Guide means 51A ... Convex part forming means 52 ... Raised part 53 ... Concave part 100 ... Biomedical solution injection tool 104 ... Check valve 110 ... Biomedical liquid injection tool kit 114 ... Biomedical liquid injection tool 120 ... Syringe 122 ... Syringe body 124... Entry / exit hole 126 .. operation part 126 A... Piston part 130 .. step part 132 .. step part 134 .. skirt part 136. 140: Opening / closing end 141: Screw hole 142 ... Screw hole 144 ... Operation unit connecting member 146 ... Operation unit gripping part 146A ... Fitting recess 146B ... Connection part 148 ... Syringe body connecting member 150 ... Syringe body gripping part 150A ... Fitting recess 152 ... Catheter 153 ... Identification means 154 ... Tubular body 155 ... Heat shrinkable tape 156 ... Chemical solution discharge port 158... Syringe mounting port 160... Chemical solution channel 162... Gas suction hole 164 .. Connection portion 166. Arrow 17 ... arrow 174 ... outer opening 176 ... inner opening 178 ... tongue portion A ... opening width B ... opening width

Claims (11)

A tubular body having a plurality of lumens therein;
A plurality of chemical solution discharge ports communicating with each of the plurality of lumens, a plurality of syringe mounting ports for mounting a plurality of syringes for injecting a chemical solution to each of the plurality of lumens, a plurality of the chemical solution discharge ports, and the plurality of the above-mentioned lumens Gas is sucked from the outside toward the syringe mounting port by connecting a plurality of chemical liquid flow channels communicating with the syringe mounting port, and connecting the outside and the plurality of syringe mounting ports with a negative pressure. And a connecting portion having a gas suction hole for,
The connecting portion has a first restricting means for restricting the chemical liquid from flowing out from the lumen side to the syringe mounting port side on the downstream side of the gas suction hole,
The biological fluid injection tool, wherein the gas suction hole has a second restricting means for restricting the chemical solution from flowing out of the gas suction hole. The gas suction hole has a plurality of gas suction passages that communicate with the plurality of syringe mounting ports, respectively, and the plurality of gas suction passages and the plurality of chemical liquid passages communicate with each other,
2. A plurality of overlapping regions in which the end region on the syringe mounting port side of the plurality of gas suction paths and the end region on the syringe mounting port side of the plurality of liquid chemical channels respectively merge. The biomedical solution infusion device described in 1.   The biological fluid injection tool according to claim 2, wherein the plurality of chemical fluid flow paths have the first regulating means on the downstream side of the overlapping region. The gas suction hole has a plurality of gas suction paths communicating with the plurality of syringe mounting ports,
The biological fluid injection tool according to any one of claims 1 to 3, wherein the second restriction means is provided in each of the plurality of gas suction paths. The gas suction hole has an intake port through which a plurality of the gas suction passages communicate with each other and sucks gas from the outside,
The biomedical solution injection device according to claim 4, wherein an opening area of the intake port is equal to or larger than a sum of opening areas of end portions on the intake port side in the plurality of gas suction paths. The gas suction hole has an intake port for sucking gas from the outside,
The biomedical solution injecting device according to any one of claims 1 to 5, wherein the intake port opens toward a distal end side of the biomedical solution injecting device. The connecting portion includes a first member having a plurality of the chemical solution discharge ports, a second member having a plurality of the syringe mounting ports, and an intermediate member positioned between the first member and the second member. Have
The first member, the second member, or the intermediate member has a recess that opens at end surfaces facing each other,
The biomedical solution injection tool according to any one of claims 1 to 6, wherein the first restricting means or the second restricting means is provided in the recess. The gas suction hole is provided with a sterilization filter,
The biomedical liquid injector according to any one of claims 1 to 7, wherein gas sucked from outside flows through the sterilization filter and flows toward the syringe mounting port.
The biomedical solution injection device according to any one of claims 1 to 8, and
A syringe body capable of containing a chemical solution or gas, an inlet / outlet through which the gas or fluid flows into or out of the syringe body attached to the syringe mounting port, and fluid to the syringe body through the inlet / outlet A biomedical solution injection tool kit comprising a plurality of syringes having an operation unit for performing an operation for inflow or outflow. A plurality of operation unit gripping units for gripping the plurality of operation units and an operation unit connecting member having a common operation surface for simultaneously pressing and operating the plurality of operation units;
The biological fluid injection tool kit according to claim 9, wherein the common operation surface is provided with guide means for indicating a region to be pushed on the common operation surface.   The top view of the common operation surface, wherein the operation portion of one of the plurality of syringes is provided in an area overlapping with the guide means or an area adjacent to the guide means. The biomedical solution injection tool kit as described.

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