JP2015113338A - Peeling of plaque in periodontal pocket and bactericide - Google Patents

Peeling of plaque in periodontal pocket and bactericide Download PDF

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Publication number
JP2015113338A
JP2015113338A JP2013273303A JP2013273303A JP2015113338A JP 2015113338 A JP2015113338 A JP 2015113338A JP 2013273303 A JP2013273303 A JP 2013273303A JP 2013273303 A JP2013273303 A JP 2013273303A JP 2015113338 A JP2015113338 A JP 2015113338A
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Prior art keywords
plaque
periodontal pocket
urea peroxide
around
peeling
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川村 弘
Hiroshi Kawamura
弘 川村
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Abstract

PROBLEM TO BE SOLVED: To peel plaque in a periodontal pocket in the location where an instrument is physically hard to reach, from a root surface safely, and to sterilize bacteria within the plaque.SOLUTION: Peeling and sterilization of plaque in a periodontal pocket can be performed by injecting mixture of around 3% hydrogen peroxide gel and around 10% of urea peroxide gel into a periodontal pocket, or injecting a thin bar-like stick of water-soluble solid containing around 10% of urea peroxide crystal into a periodontal pocket.

Description

本発明は、歯周ポケット内プラークの除去の際、物理的に器具の到達の困難な場所に対して根面からのプラークの剥離を容易にし、かつ殺菌効果の期待できるジェルと固体の細い棒状のチップからなるプラーク剥離及び殺菌剤に関する。When removing plaque in the periodontal pocket, the present invention makes it easy to peel the plaque from the root surface to a place where it is physically difficult to reach the device, and can be expected to have a bactericidal effect. The present invention relates to a plaque exfoliating and disinfecting agent comprising the above chip.

従来歯周病の治療,予防のために歯周ポケット内プラークを手用スケーラーや超音波スケーラーなどで除去していたが、盲目的な操作において歯周ポケット内の複雑な場所までの器具の到達が困難であり、プラークの取り残しがどうしてもあった。Previously, plaque in the periodontal pocket was removed with a manual scaler or ultrasonic scaler to treat or prevent periodontal disease, but the device reached a complex place in the periodontal pocket in a blind operation. It was difficult and the plaque was left behind.

また、歯周ポケット内を液体の殺菌剤で剥離及び殺菌しようとしても、ポケット内のイリゲーションでは根面からのプラークの剥離は困難であり、殺菌に関してもポケット内の浮遊菌には効果があるが、液体であるためすぐにポケットの外に流出してしまいプラーク内部まで殺菌剤が浸透させることが困難であった。In addition, even if an attempt is made to detach and sterilize the periodontal pocket with a liquid disinfectant, it is difficult to detach the plaque from the root surface by irrigation in the pocket. Since it is a liquid, it immediately flows out of the pocket and it is difficult for the disinfectant to penetrate into the plaque.

又、口腔内粘膜に使用できる殺菌剤としてポピドンヨードがあるが、ヨードによるアナフィラキシーショックを引き起こす恐れがある。
他によく使われる殺菌剤としてオキシドール、すなわち3%前後の過酸化水素溶液があり比較的安全に使用できカタラーゼとの反応で発泡してプラークの根面からの剥離に有効であるが、カタラーゼとの反応により瞬時に酸素と水に分解し、発泡力と殺菌性の持続性の欠ける。
In addition, popidone iodine is a bactericidal agent that can be used for the oral mucosa, but it may cause anaphylactic shock due to iodine.
Another commonly used disinfectant is oxidol, a hydrogen peroxide solution of around 3%, which can be used relatively safely and is effective for exfoliating from the root surface of plaque by reacting with catalase. The reaction instantly decomposes into oxygen and water, and lacks foaming power and sustainability of bactericidal properties.

本発明は、歯周ポケット内の器具の到達の困難な場所のプラークを、安全に根面から剥離しかつプラーク内部の細菌まで殺菌することを目的とする。An object of the present invention is to safely detach plaque from a root surface and disinfect bacteria inside the plaque in a place where it is difficult to reach an instrument in a periodontal pocket.

3%前後過酸化水素のジェルと10%前後過酸化尿素のジェルを歯周ポケット内の中に注入する直前に混和し、歯周ポケット内に注入することによりまずジェル状の過酸化水素によるカタラーゼとの瞬時の反応で酸素の発泡が起こり、この発泡力によりプラークを根面から剥離したり、またプラークの凝集に隙間ができることによりそこにジェル状の過酸化尿素が浸透する。
そして過酸化尿素の分解で過酸化水素の持続的な供給ができるため、持続的剥離効果と、殺菌効果が期待できる。
About 3% hydrogen peroxide gel and about 10% urea peroxide gel are mixed immediately before being injected into the periodontal pocket, and then injected into the periodontal pocket to first form a gel-like hydrogen peroxide catalase. Oxygen foaming occurs due to an instantaneous reaction with the above, and the foaming force causes the plaque to peel from the root surface, and a gap is formed in the aggregation of the plaque, so that the gel-like urea peroxide permeates there.
Since hydrogen peroxide can be continuously supplied by decomposition of urea peroxide, a continuous peeling effect and a bactericidal effect can be expected.

又は10%前後の過酸化尿素の結晶を含んだカルボキシルメチルセルロースなどの水溶性の増粘材よりなる固体の細い棒状のチップを歯周ポケット内に注入して唾液などの水分で少しずつ溶解しながら過酸化水素を供給し、持続的剥離効果と殺菌効果が期待できる。Alternatively, a solid thin rod-shaped chip made of a water-soluble thickener such as carboxymethylcellulose containing about 10% urea peroxide crystals is injected into the periodontal pocket and dissolved gradually with moisture such as saliva. Hydrogen peroxide can be supplied, and a continuous peeling effect and bactericidal effect can be expected.

本発明は歯周ポケット内プラークの手用スケーラーや超音波スケーラーで物理的に除去できなかった複雑な場所のプラークに対して、3%前後の過酸化水素のジェルと10%前後の過酸化尿素のジェルの混和物がカタラーゼとの反応時にでる酸素の発泡力でプラークを根面から剥離させかつ、混和物の粘性によりポケット内に長く貯留できるため持続的な殺菌力を供給する効果がある。
又は、10%前後の過酸化尿素の結晶を含んだ、細い棒状の固体のスティックを歯周ポケット内に注入し少しずつ溶解させることにより、持続的なプラーク剥離効果と殺菌効果がある。
本発明の主成分は活性酸素である過酸化水素であるが、歯周ポケット内の歯周病関連の細菌は偏性嫌気性菌がほとんどで、菌内にカタラーゼを持っていないので過酸化水素は菌に対して致死性の障害を与える。
前述の発泡を引き起こすカタラーゼは、ポケット内の浸出液中やプラークの一部の宿主側の組織破片由来のカタラーゼである。
他の口腔内に使用できる殺菌剤として、ポピドンヨード、アクリノール、塩化ベンゼトニウム、又国外では使えるクロルヘキシジンなどがあるがいずれも発泡する能力はない。
またヨード、クロルヘキシジンはアナフィラキシーショックの報告が多数あり危険を伴う。
以上により本発明は、歯周ポケット内プラークの剥離及び殺菌することにより歯周病の治療、予防に有効である。
The present invention relates to about 3% hydrogen peroxide gel and about 10% urea peroxide for plaques in complex places that could not be physically removed by a manual scaler or ultrasonic scaler in the periodontal pocket. The mixture of gels has an effect of supplying a continuous bactericidal power because the plaque is peeled off from the root surface by the foaming force of oxygen generated during the reaction with catalase and can be stored in the pocket for a long time due to the viscosity of the mixture.
Alternatively, a thin stick-shaped solid stick containing about 10% urea peroxide crystals is injected into the periodontal pocket and gradually dissolved, thereby providing a continuous plaque peeling effect and a bactericidal effect.
The main component of the present invention is hydrogen peroxide, which is active oxygen, but periodontal disease-related bacteria in the periodontal pocket are mostly obligate anaerobic bacteria and do not have catalase in the bacteria. Causes lethal damage to bacteria.
The catalase causing foaming is a catalase derived from tissue debris in the exudate in the pocket or a part of the host of the plaque.
Other bactericides that can be used in the oral cavity include popidone iodine, acrinol, benzethonium chloride, and chlorhexidine that can be used overseas, but none of them have the ability to foam.
Iodo and chlorhexidine are dangerous because there are many reports of anaphylactic shock.
As described above, the present invention is effective in the treatment and prevention of periodontal disease by peeling and sterilizing the plaque in the periodontal pocket.

本発明の成分となっている3%前後の過酸化水素のジェルと10%前後の過酸化尿素のジェルを使用直前に混和し細いノズルのついたシリンジで、歯周ポケット内に注入し10分間停留させておく。
又は10%前後の過酸化尿素の結晶を含んだ水溶性の固形の細い棒状のスティックを歯周ポケット内に注入し唾液などの水分で溶解させながら、10分間停留させておく。
その後手用スケーラーや超音波スケーラーを使い、通常のスケーリング、ルートプレーニングを行う。
About 3% hydrogen peroxide gel and about 10% urea peroxide gel, which are the components of the present invention, are mixed immediately before use and injected into the periodontal pocket with a syringe with a thin nozzle for 10 minutes. Let it stop.
Alternatively, a water-soluble solid thin stick-like stick containing about 10% urea peroxide crystals is injected into the periodontal pocket and allowed to stand for 10 minutes while being dissolved with water such as saliva.
After that, normal scaling and route planing are performed using a hand scaler and an ultrasonic scaler.

Claims (2)

3%前後の過酸化水素のジェルと10%前後の過酸化尿素のジェルの混合物からなる混和剤による、歯周ポケット内プラークの剥離及び殺菌剤。Plaque removal and disinfectant in periodontal pockets with an admixture consisting of a mixture of around 3% hydrogen peroxide gel and around 10% urea peroxide gel. 10%前後の過酸化尿素の液体をカルボキシルメチルセルロースなどの水溶性の増粘剤でジェル化し、これを薄い被膜にし乾燥させて薄いフィルム状にする。
そしてこのフィルムを細く巻いて10%過酸化尿素を含んだ細い棒状の固体のチップからなる、歯周ポケット内プラークの剥離及び殺菌剤。
About 10% urea peroxide liquid is gelled with a water-soluble thickening agent such as carboxymethylcellulose, which is made into a thin film and dried to form a thin film.
Then, the plaque in the periodontal pocket is peeled off and sterilized, which is made of a thin rod-shaped solid chip containing 10% urea peroxide by thinly winding this film.
JP2013273303A 2013-12-10 2013-12-10 Peeling of plaque in periodontal pocket and bactericide Pending JP2015113338A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019520350A (en) * 2016-06-22 2019-07-18 スリーエム イノベイティブ プロパティズ カンパニー Method and kit for removing tartar

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019520350A (en) * 2016-06-22 2019-07-18 スリーエム イノベイティブ プロパティズ カンパニー Method and kit for removing tartar
JP7292037B2 (en) 2016-06-22 2023-06-16 スリーエム イノベイティブ プロパティズ カンパニー Method and kit for removing tartar

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