JP2014527816A5 - - Google Patents
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- JP2014527816A5 JP2014527816A5 JP2014530760A JP2014530760A JP2014527816A5 JP 2014527816 A5 JP2014527816 A5 JP 2014527816A5 JP 2014530760 A JP2014530760 A JP 2014530760A JP 2014530760 A JP2014530760 A JP 2014530760A JP 2014527816 A5 JP2014527816 A5 JP 2014527816A5
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- JP
- Japan
- Prior art keywords
- patient
- level
- levels
- gene
- value
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 101000737052 Homo sapiens Coiled-coil domain-containing protein 54 Proteins 0.000 claims description 55
- 101000824971 Homo sapiens Sperm surface protein Sp17 Proteins 0.000 claims description 55
- 102100035167 Coiled-coil domain-containing protein 54 Human genes 0.000 claims description 44
- 230000014509 gene expression Effects 0.000 claims description 44
- 238000000034 method Methods 0.000 claims description 38
- 239000000523 sample Substances 0.000 claims description 21
- 206010033128 Ovarian cancer Diseases 0.000 claims description 19
- 206010061535 Ovarian neoplasm Diseases 0.000 claims description 19
- 230000004083 survival effect Effects 0.000 claims description 15
- 238000003745 diagnosis Methods 0.000 claims description 4
- 108020004999 messenger RNA Proteins 0.000 claims description 4
- 238000004393 prognosis Methods 0.000 claims description 4
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 241000124008 Mammalia Species 0.000 claims description 2
- 241001465754 Metazoa Species 0.000 claims description 2
- 241001494479 Pecora Species 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 239000003153 chemical reaction reagent Substances 0.000 claims description 2
- 238000003364 immunohistochemistry Methods 0.000 claims description 2
- 238000007901 in situ hybridization Methods 0.000 claims description 2
- 238000002493 microarray Methods 0.000 claims description 2
- 239000013610 patient sample Substances 0.000 claims description 2
- 229920001184 polypeptide Polymers 0.000 claims description 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 2
- 238000003753 real-time PCR Methods 0.000 claims description 2
- 210000002966 serum Anatomy 0.000 claims description 2
- 210000002700 urine Anatomy 0.000 claims description 2
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161535309P | 2011-09-15 | 2011-09-15 | |
| US61/535,309 | 2011-09-15 | ||
| PCT/US2012/054914 WO2013040071A2 (en) | 2011-09-15 | 2012-09-12 | Sperm protein as a detection biomarker of early stage ovarian cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014527816A JP2014527816A (ja) | 2014-10-23 |
| JP2014527816A5 true JP2014527816A5 (https=) | 2015-11-05 |
Family
ID=47883948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014530760A Pending JP2014527816A (ja) | 2011-09-15 | 2012-09-12 | 初期卵巣がんの検出マーカーとしての精子タンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150110897A1 (https=) |
| EP (1) | EP2756100A4 (https=) |
| JP (1) | JP2014527816A (https=) |
| CN (1) | CN104039980A (https=) |
| CA (1) | CA2848578A1 (https=) |
| IN (1) | IN2014CN02496A (https=) |
| WO (1) | WO2013040071A2 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104807997A (zh) * | 2015-05-05 | 2015-07-29 | 南京格耀生物科技有限公司 | 一种基于化学发光法检测ca125和sp17含量的试剂盒及方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002306600A1 (en) * | 2001-02-26 | 2002-09-12 | Albany Medical College | Sperm protein 17 for the diagnosis and treatment of cancer |
| US7189507B2 (en) * | 2001-06-18 | 2007-03-13 | Pdl Biopharma, Inc. | Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer |
| AT501348B1 (de) * | 2005-01-31 | 2008-10-15 | Vitateq Biotechnology Gmbh | Verfahren zur tumordiagnose |
| CN100334110C (zh) * | 2005-09-01 | 2007-08-29 | 中国人民解放军南京军区南京总医院 | 一种精子蛋白单克隆抗体及其制备方法和用途 |
| WO2007058536A1 (en) * | 2005-11-16 | 2007-05-24 | Pantarhei Bioscience B.V. | Pharmaceutical composition for treating or preventing ovarian cancer |
-
2012
- 2012-09-12 IN IN2496CHN2014 patent/IN2014CN02496A/en unknown
- 2012-09-12 CA CA 2848578 patent/CA2848578A1/en not_active Abandoned
- 2012-09-12 EP EP12831144.6A patent/EP2756100A4/en not_active Withdrawn
- 2012-09-12 CN CN201280054743.6A patent/CN104039980A/zh active Pending
- 2012-09-12 WO PCT/US2012/054914 patent/WO2013040071A2/en not_active Ceased
- 2012-09-12 US US14/345,208 patent/US20150110897A1/en not_active Abandoned
- 2012-09-12 JP JP2014530760A patent/JP2014527816A/ja active Pending
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