JP2014516627A5 - - Google Patents
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- Publication number
- JP2014516627A5 JP2014516627A5 JP2014505357A JP2014505357A JP2014516627A5 JP 2014516627 A5 JP2014516627 A5 JP 2014516627A5 JP 2014505357 A JP2014505357 A JP 2014505357A JP 2014505357 A JP2014505357 A JP 2014505357A JP 2014516627 A5 JP2014516627 A5 JP 2014516627A5
- Authority
- JP
- Japan
- Prior art keywords
- dendrimer
- kit
- polymer
- solution
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000412 dendrimer Substances 0.000 claims 22
- 229920000736 dendritic polymer Polymers 0.000 claims 22
- 229920000642 polymer Polymers 0.000 claims 17
- 229920002307 Dextran Polymers 0.000 claims 3
- 239000000853 adhesive Substances 0.000 claims 3
- 230000001070 adhesive effect Effects 0.000 claims 3
- 125000003172 aldehyde group Chemical group 0.000 claims 3
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 claims 3
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 150000001299 aldehydes Chemical class 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 238000012377 drug delivery Methods 0.000 claims 1
- 239000004088 foaming agent Substances 0.000 claims 1
- 238000007306 functionalization reaction Methods 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- -1 pH adjusters Substances 0.000 claims 1
- 229920000962 poly(amidoamine) Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161474984P | 2011-04-13 | 2011-04-13 | |
| US61/474,984 | 2011-04-13 | ||
| PCT/US2012/033604 WO2012142470A1 (en) | 2011-04-13 | 2012-04-13 | Biocompatible adhesive materials and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014516627A JP2014516627A (ja) | 2014-07-17 |
| JP2014516627A5 true JP2014516627A5 (enExample) | 2015-05-07 |
| JP5980905B2 JP5980905B2 (ja) | 2016-08-31 |
Family
ID=46026933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014505357A Active JP5980905B2 (ja) | 2011-04-13 | 2012-04-13 | 生体適合性接着剤材料及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8802072B2 (enExample) |
| EP (1) | EP2696906B1 (enExample) |
| JP (1) | JP5980905B2 (enExample) |
| ES (1) | ES2548406T3 (enExample) |
| WO (1) | WO2012142470A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3086821B1 (en) * | 2013-12-23 | 2020-04-01 | Massachusetts Institute of Technology | Controllably degradable compositions and methods |
| EP3313461A1 (en) * | 2015-06-24 | 2018-05-02 | Massachusetts Institute Of Technology | Controllably degradable compositions and methods |
| US9572555B1 (en) * | 2015-09-24 | 2017-02-21 | Ethicon, Inc. | Spray or drip tips having multiple outlet channels |
| US10342894B2 (en) | 2015-10-16 | 2019-07-09 | Massachusetts Institute Of Technology | Hydrogel composites, compositions, and methods |
| CA3013922A1 (en) * | 2016-02-08 | 2017-08-17 | The Johns Hopkins University | Dendrimer-bioadhesive polymer hydrogel nanoglue and use thereof |
| US11020160B2 (en) * | 2016-03-21 | 2021-06-01 | Warsaw Orthopedic, Inc. | Surgical injection system and method |
| EP3570851B1 (en) * | 2017-01-17 | 2024-09-18 | Tufts Medical Center, Inc. | Adoptive transfer of plasmacytoid dendritic cells to prevent or treat ocular diseases and conditions |
| WO2018201007A2 (en) | 2017-04-27 | 2018-11-01 | The Johns Hopkins University | Dendrimer compositions for use in angiography |
| CA3082121C (en) | 2017-11-10 | 2023-01-24 | The Johns Hopkins University | Dendrimer delivery system and methods of use thereof |
| CA3030416A1 (en) | 2018-01-18 | 2019-07-18 | Research Triangle Institute | Polyamine phosphorus dendrimer materials for carbon dioxide capture |
| US20210222035A1 (en) * | 2018-05-15 | 2021-07-22 | Biodevek, Inc. | Biocompatible adhesive materials with ionic and covalent interaction |
| US12343698B2 (en) | 2019-01-17 | 2025-07-01 | Research Triangle Institute | Polyamine phosphorus dendrimer materials for metal sequestration |
| JP7759322B2 (ja) | 2019-12-04 | 2025-10-23 | アシュバッタ セラピューティクス， インコーポレイテッド | 眼に薬物送達するためのデンドリマー組成物および方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4768523A (en) | 1981-04-29 | 1988-09-06 | Lifecore Biomedical, Inc. | Hydrogel adhesive |
| US5306504A (en) | 1992-12-09 | 1994-04-26 | Paper Manufactures Company | Skin adhesive hydrogel, its preparation and uses |
| US20040131582A1 (en) | 2002-02-26 | 2004-07-08 | Grinstaff Mark W. | Novel dendritic polymers and their biomedical uses |
| EP1364663A1 (en) | 2002-05-21 | 2003-11-26 | Commonwealth Scientific And Industrial Research Organisation | Ocular devices with functionalized surface with adhesive properties |
| EP1796746B1 (en) | 2004-10-07 | 2011-05-04 | E.I. Du Pont De Nemours And Company | Polysaccharide-based polymer tissue adhesive for medical use |
| US8790632B2 (en) * | 2004-10-07 | 2014-07-29 | Actamax Surgical Materials, Llc | Polymer-based tissue-adhesive form medical use |
| EP1957089A4 (en) * | 2005-12-06 | 2012-06-20 | Tyco Healthcare | CARBODIIMIDE CROSSLINKING OF FUNCTIONALIZED POLYETHYLENE GLYCOLS |
| CN105833337B (zh) | 2008-11-19 | 2020-01-21 | 阿克塔马克斯手术器材有限责任公司 | 纤维组织封合剂及其使用方法 |
| US8778326B2 (en) | 2009-07-02 | 2014-07-15 | Actamax Surgical Materials, Llc | Hydrogel tissue adhesive for medical use |
-
2012
- 2012-04-13 ES ES12718802.7T patent/ES2548406T3/es active Active
- 2012-04-13 WO PCT/US2012/033604 patent/WO2012142470A1/en not_active Ceased
- 2012-04-13 EP EP12718802.7A patent/EP2696906B1/en active Active
- 2012-04-13 US US13/446,712 patent/US8802072B2/en active Active
- 2012-04-13 JP JP2014505357A patent/JP5980905B2/ja active Active
-
2014
- 2014-07-30 US US14/446,805 patent/US9707313B2/en active Active
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