JP2014507164A5 - - Google Patents

Download PDF

Info

Publication number
JP2014507164A5
JP2014507164A5 JP2013555620A JP2013555620A JP2014507164A5 JP 2014507164 A5 JP2014507164 A5 JP 2014507164A5 JP 2013555620 A JP2013555620 A JP 2013555620A JP 2013555620 A JP2013555620 A JP 2013555620A JP 2014507164 A5 JP2014507164 A5 JP 2014507164A5
Authority
JP
Japan
Prior art keywords
fractions
nucleic acid
maternal
allele
paternal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013555620A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014507164A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/026623 external-priority patent/WO2012116331A2/en
Publication of JP2014507164A publication Critical patent/JP2014507164A/ja
Publication of JP2014507164A5 publication Critical patent/JP2014507164A5/ja
Pending legal-status Critical Current

Links

JP2013555620A 2011-02-25 2012-02-24 ハプロタイプ決定のための方法およびシステム Pending JP2014507164A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161446890P 2011-02-25 2011-02-25
US61/446,890 2011-02-25
US201161509960P 2011-07-20 2011-07-20
US61/509,960 2011-07-20
PCT/US2012/026623 WO2012116331A2 (en) 2011-02-25 2012-02-24 Methods and systems for haplotype determination

Publications (2)

Publication Number Publication Date
JP2014507164A JP2014507164A (ja) 2014-03-27
JP2014507164A5 true JP2014507164A5 (cg-RX-API-DMAC7.html) 2015-04-09

Family

ID=46721484

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013555620A Pending JP2014507164A (ja) 2011-02-25 2012-02-24 ハプロタイプ決定のための方法およびシステム

Country Status (7)

Country Link
US (1) US20140045706A1 (cg-RX-API-DMAC7.html)
EP (1) EP2678449A4 (cg-RX-API-DMAC7.html)
JP (1) JP2014507164A (cg-RX-API-DMAC7.html)
CN (1) CN103492588A (cg-RX-API-DMAC7.html)
AU (1) AU2012222108A1 (cg-RX-API-DMAC7.html)
CA (1) CA2824431A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012116331A2 (cg-RX-API-DMAC7.html)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2673380B1 (en) 2011-02-09 2018-12-12 Bio-Rad Laboratories, Inc. Analysis of nucleic acids
BR112015003354A8 (pt) 2012-08-14 2018-01-16 10X Genomics Inc métodos e composições de microcápsula
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10584381B2 (en) 2012-08-14 2020-03-10 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9411930B2 (en) * 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
CA2900481A1 (en) 2013-02-08 2014-08-14 10X Genomics, Inc. Polynucleotide barcode generation
US10395758B2 (en) 2013-08-30 2019-08-27 10X Genomics, Inc. Sequencing methods
EP3038834B1 (en) 2013-08-30 2018-12-12 Illumina, Inc. Manipulation of droplets on hydrophilic or variegated-hydrophilic surfaces
US10172916B2 (en) 2013-11-15 2019-01-08 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating heart failure with agonists of hypocretin receptor 2
US9824068B2 (en) 2013-12-16 2017-11-21 10X Genomics, Inc. Methods and apparatus for sorting data
KR102596508B1 (ko) 2014-04-10 2023-10-30 10엑스 제노믹스, 인크. 시약을 캡슐화 및 구획화하기 위한 유체 디바이스, 시스템, 및 방법, 및 이의 응용
AU2015279546B2 (en) 2014-06-26 2021-04-08 10X Genomics, Inc. Processes and systems for nucleic acid sequence assembly
KR20170026383A (ko) 2014-06-26 2017-03-08 10엑스 제노믹스, 인크. 핵산 서열의 분석
EP4574974A3 (en) 2014-06-26 2025-10-08 10x Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
US12312640B2 (en) 2014-06-26 2025-05-27 10X Genomics, Inc. Analysis of nucleic acid sequences
US10526641B2 (en) 2014-08-01 2020-01-07 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
JP6630347B2 (ja) * 2014-09-03 2020-01-15 ナントヘルス，インコーポレーテッド 合成ゲノム変異体ベースの安全なトランザクション装置、システム、及び方法
US10227650B2 (en) * 2014-11-14 2019-03-12 Athena Diagnostics, Inc. Methods to detect a silent carrier of a null allele genotype
SG11201705615UA (en) 2015-01-12 2017-08-30 10X Genomics Inc Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
EP3245605B1 (en) 2015-01-13 2022-04-20 10X Genomics, Inc. Systems and methods for visualizing structural variation and phasing information
JP2018513445A (ja) 2015-02-09 2018-05-24 １０エックス ゲノミクス，インコーポレイテッド 構造変異の特定及びバリアントコールデータを用いたフェージングのためのシステム及び方法
WO2016149684A2 (en) * 2015-03-18 2016-09-22 The Board Of Trustees Of The Leland Stanford Junior University Haplotype based generalizable allele specific silencing for therapy of cardiovascular disease
WO2016154540A1 (en) 2015-03-26 2016-09-29 Dovetail Genomics Llc Physical linkage preservation in dna storage
CN105046105B (zh) * 2015-07-09 2018-02-02 天津诺禾医学检验所有限公司 染色体跨度的单体型图及其构建方法
CN105385755A (zh) * 2015-11-05 2016-03-09 上海序康医疗科技有限公司 一种利用多重pcr技术进行snp-单体型分析的方法
US11371094B2 (en) 2015-11-19 2022-06-28 10X Genomics, Inc. Systems and methods for nucleic acid processing using degenerate nucleotides
JP6735348B2 (ja) 2016-02-11 2020-08-05 １０エックス ジェノミクス， インコーポレイテッド 全ゲノム配列データのデノボアセンブリのためのシステム、方法及び媒体
US10975417B2 (en) 2016-02-23 2021-04-13 Dovetail Genomics, Llc Generation of phased read-sets for genome assembly and haplotype phasing
CN109477101B (zh) 2016-05-13 2022-11-18 多弗泰尔基因组学有限责任公司 从保存的样品中回收长范围连锁信息
KR101815529B1 (ko) * 2016-07-29 2018-01-30 (주)신테카바이오 휴먼 하플로타이핑 시스템 및 방법
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US12264411B2 (en) 2017-01-30 2025-04-01 10X Genomics, Inc. Methods and systems for analysis
EP4310183B1 (en) 2017-01-30 2025-07-09 10X Genomics, Inc. Methods and systems for droplet-based single cell barcoding
US10995333B2 (en) 2017-02-06 2021-05-04 10X Genomics, Inc. Systems and methods for nucleic acid preparation
CN110870018B (zh) 2017-05-19 2024-11-22 10X基因组学有限公司 用于分析数据集的系统和方法
US10837047B2 (en) 2017-10-04 2020-11-17 10X Genomics, Inc. Compositions, methods, and systems for bead formation using improved polymers
WO2019084043A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. METHODS AND SYSTEMS FOR NUCLEIC ACID PREPARATION AND CHROMATIN ANALYSIS
CN114525273B (zh) 2017-10-27 2025-01-28 10X基因组学有限公司 用于样品制备和分析的方法和系统
WO2019099751A1 (en) 2017-11-15 2019-05-23 10X Genomics, Inc. Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
WO2019108851A1 (en) 2017-11-30 2019-06-06 10X Genomics, Inc. Systems and methods for nucleic acid preparation and analysis
WO2019118355A1 (en) 2017-12-12 2019-06-20 10X Genomics, Inc. Systems and methods for single cell processing
CN118547046A (zh) 2017-12-22 2024-08-27 10X基因组学有限公司 用于处理来自一个或多个细胞的核酸分子的系统和方法
WO2019152543A1 (en) 2018-01-31 2019-08-08 Dovetail Genomics, Llc Sample prep for dna linkage recovery
CN112005115A (zh) 2018-02-12 2020-11-27 10X基因组学有限公司 表征来自单个细胞或细胞群体的多种分析物的方法
US11639928B2 (en) 2018-02-22 2023-05-02 10X Genomics, Inc. Methods and systems for characterizing analytes from individual cells or cell populations
WO2019169028A1 (en) 2018-02-28 2019-09-06 10X Genomics, Inc. Transcriptome sequencing through random ligation
SG11202009889VA (en) 2018-04-06 2020-11-27 10X Genomics Inc Systems and methods for quality control in single cell processing
WO2019217758A1 (en) 2018-05-10 2019-11-14 10X Genomics, Inc. Methods and systems for molecular library generation
US11932899B2 (en) 2018-06-07 2024-03-19 10X Genomics, Inc. Methods and systems for characterizing nucleic acid molecules
US11703427B2 (en) 2018-06-25 2023-07-18 10X Genomics, Inc. Methods and systems for cell and bead processing
US12188014B1 (en) 2018-07-25 2025-01-07 10X Genomics, Inc. Compositions and methods for nucleic acid processing using blocking agents
US20200032335A1 (en) 2018-07-27 2020-01-30 10X Genomics, Inc. Systems and methods for metabolome analysis
EP3830289A1 (en) 2018-08-03 2021-06-09 10X Genomics, Inc. Methods and systems to minimize barcode exchange
US12065688B2 (en) 2018-08-20 2024-08-20 10X Genomics, Inc. Compositions and methods for cellular processing
WO2020041148A1 (en) 2018-08-20 2020-02-27 10X Genomics, Inc. Methods and systems for detection of protein-dna interactions using proximity ligation
US11459607B1 (en) 2018-12-10 2022-10-04 10X Genomics, Inc. Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes
US12169198B2 (en) 2019-01-08 2024-12-17 10X Genomics, Inc. Systems and methods for sample analysis
US11845983B1 (en) 2019-01-09 2023-12-19 10X Genomics, Inc. Methods and systems for multiplexing of droplet based assays
US12275993B2 (en) 2019-02-12 2025-04-15 10X Genomics, Inc. Analysis of nucleic acid sequences
US12305239B2 (en) 2019-02-12 2025-05-20 10X Genomics, Inc. Analysis of nucleic acid sequences
US11851683B1 (en) 2019-02-12 2023-12-26 10X Genomics, Inc. Methods and systems for selective analysis of cellular samples
WO2020168013A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Methods for processing nucleic acid molecules
US11467153B2 (en) 2019-02-12 2022-10-11 10X Genomics, Inc. Methods for processing nucleic acid molecules
WO2020167862A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Systems and methods for transfer of reagents between droplets
WO2020167866A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Systems and methods for transposon loading
US11655499B1 (en) 2019-02-25 2023-05-23 10X Genomics, Inc. Detection of sequence elements in nucleic acid molecules
US11920183B2 (en) 2019-03-11 2024-03-05 10X Genomics, Inc. Systems and methods for processing optically tagged beads
US12235262B1 (en) 2019-09-09 2025-02-25 10X Genomics, Inc. Methods and systems for single cell protein analysis
US12449419B1 (en) 2020-02-12 2025-10-21 10X Genomics, Inc. Methods for detecting binding of peptide-MHC monomers to T cells
US12421558B2 (en) 2020-02-13 2025-09-23 10X Genomics, Inc. Systems and methods for joint interactive visualization of gene expression and DNA chromatin accessibility
US11851700B1 (en) 2020-05-13 2023-12-26 10X Genomics, Inc. Methods, kits, and compositions for processing extracellular molecules
US12480158B1 (en) 2020-11-05 2025-11-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US12084715B1 (en) 2020-11-05 2024-09-10 10X Genomics, Inc. Methods and systems for reducing artifactual antisense products
US12398262B1 (en) 2021-01-22 2025-08-26 10X Genomics, Inc. Triblock copolymer-based cell stabilization and fixation system and methods of use thereof
CN120158497A (zh) 2021-02-23 2025-06-17 10X基因组学有限公司 基于探针的核酸和蛋白质分析
CN112795563A (zh) * 2021-03-23 2021-05-14 上海欣百诺生物科技有限公司 生物素化的转座体在回收CUT&Tag或ATAC-seq产物中的用途及方法
CA3252346A1 (en) 2022-05-11 2023-11-16 Provincial Health Services Authority METHOD AND APPARATUS FOR DETECTING THE DISEASE ALLELE IN THE ORIGINAL PARENT FOR THE DIAGNOSIS AND MANAGEMENT OF GENETIC DISEASES
CN115992261B (zh) * 2022-12-13 2025-06-24 中国科学院海洋研究所 一种构建牡蛎单倍型基因组的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE435925T1 (de) * 2003-01-17 2009-07-15 Univ Boston Haplotypanalyse
US20040146870A1 (en) * 2003-01-27 2004-07-29 Guochun Liao Systems and methods for predicting specific genetic loci that affect phenotypic traits
CA2518904A1 (en) * 2003-03-12 2004-09-23 Cleveland State University Molecular haplotyping of genomic dna
US20040185453A1 (en) * 2003-03-21 2004-09-23 Joel Myerson Affinity based methods for separating homologous parental genetic material and uses thereof
WO2005082110A2 (en) * 2004-02-26 2005-09-09 Illumina Inc. Haplotype markers for diagnosing susceptibility to immunological conditions
GB0523276D0 (en) * 2005-11-15 2005-12-21 London Bridge Fertility Chromosomal analysis by molecular karyotyping
US8592150B2 (en) * 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
WO2010044923A1 (en) * 2008-10-21 2010-04-22 Morehouse School Of Medicine Methods for haplotype determination by haplodissection
EP2443236B1 (en) * 2009-06-15 2015-05-13 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing

Similar Documents

Publication Publication Date Title
JP2014507164A5 (cg-RX-API-DMAC7.html)
Naidoo et al. Human genetics and genomics a decade after the release of the draft sequence of the human genome
Kidd et al. Mapping and sequencing of structural variation from eight human genomes
Wiltshire et al. Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse
Guo et al. Next generation sequencing of SNPs using the HID-Ion AmpliSeq™ Identity Panel on the Ion Torrent PGM™ platform
Hodges et al. Genome-wide in situ exon capture for selective resequencing
Ozcelik et al. Long-range PCR and next-generation sequencing of BRCA1 and BRCA2 in breast cancer
Verlaan et al. Targeted screening of cis-regulatory variation in human haplotypes
US20190002979A1 (en) Haplotyping of hla loci with ultra-deep shotgun sequencing
Valencia et al. Assessment of target enrichment platforms using massively parallel sequencing for the mutation detection for congenital muscular dystrophy
Yuen et al. Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies
Lee et al. Improved reduced representation bisulfite sequencing for epigenomic profiling of clinical samples
CN103492588A (zh) 用于单体型测定的方法和系统
US20150203907A1 (en) Genome capture and sequencing to determine genome-wide copy number variation
Lin et al. High-resolution melting analyses for genetic variants in ARID5B and IKZF1 with childhood acute lymphoblastic leukemia susceptibility loci in Taiwan
Kwon et al. Investigation into the sequence structure of 23 Y chromosomal STR loci using massively parallel sequencing
Chaisson et al. Advances in the discovery and analyses of human tandem repeats
Craig et al. Applications of whole-genome high-density SNP genotyping
Wang et al. Tri-allelic pattern of short tandem repeats identifies the murderer among identical twins and suggests an embryonic mutational origin
Butz et al. Brief summary of the most important molecular genetic methods (PCR, qPCR, microarray, next-generation sequencing, etc.)
ElSharawy et al. Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing
WO2015200701A2 (en) Software haplotying of hla loci
McIver et al. Population-scale analysis of human microsatellites reveals novel sources of exonic variation
Surrey et al. The genomic era of clinical oncology: integrated genomic analysis for precision cancer care
Lee et al. Improving the efficiency of genomic loci capture using oligonucleotide arrays for high throughput resequencing