JP2014501284A - Ｃｏｘ−２阻害剤および関連化合物、ならびにそれらを送達するためのシステムおよび方法 - Google Patents

Ｃｏｘ−２阻害剤および関連化合物、ならびにそれらを送達するためのシステムおよび方法 Download PDF

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JP2014501284A
JP2014501284A JP2013547684A JP2013547684A JP2014501284A JP 2014501284 A JP2014501284 A JP 2014501284A JP 2013547684 A JP2013547684 A JP 2013547684A JP 2013547684 A JP2013547684 A JP 2013547684A JP 2014501284 A JP2014501284 A JP 2014501284A
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JP2014501284A5 (OSRAM
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エリック ティー． フォッセル，
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ストラテジック サイエンス アンド テクノロジーズ， エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013547684A 2010-12-29 2011-12-29 Ｃｏｘ−２阻害剤および関連化合物、ならびにそれらを送達するためのシステムおよび方法 Pending JP2014501284A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201061428057P 2010-12-29 2010-12-29
US201061428213P 2010-12-29 2010-12-29
US61/428,057 2010-12-29
US61/428,213 2010-12-29
PCT/US2011/067990 WO2012092525A1 (en) 2010-12-29 2011-12-29 Cox-2 inhibitors and related compounds, and systems and methods for delivery thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015239307A Division JP2016033168A (ja) 2010-12-29 2015-12-08 Ｃｏｘ−２阻害剤および関連化合物、ならびにそれらを送達するためのシステムおよび方法

Publications (2)

Publication Number Publication Date
JP2014501284A true JP2014501284A (ja) 2014-01-20
JP2014501284A5 JP2014501284A5 (OSRAM) 2015-02-19

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013547684A Pending JP2014501284A (ja) 2010-12-29 2011-12-29 Ｃｏｘ−２阻害剤および関連化合物、ならびにそれらを送達するためのシステムおよび方法
JP2015239307A Pending JP2016033168A (ja) 2010-12-29 2015-12-08 Ｃｏｘ−２阻害剤および関連化合物、ならびにそれらを送達するためのシステムおよび方法

Family Applications After (1)

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JP2015239307A Pending JP2016033168A (ja) 2010-12-29 2015-12-08 Ｃｏｘ−２阻害剤および関連化合物、ならびにそれらを送達するためのシステムおよび方法

Country Status (5)

Country Link
US (1) US20140004177A1 (OSRAM)
EP (1) EP2658553A4 (OSRAM)
JP (2) JP2014501284A (OSRAM)
CN (1) CN103442722A (OSRAM)
WO (1) WO2012092525A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023510354A (ja) * 2020-01-10 2023-03-13 ブリオリ バイオテック，エルエルシー ロフェコキシブを含有する外用組成物並びにそれを製造及び使用する方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
CA2563670C (en) * 2004-04-19 2014-09-16 Strategic Science & Technologies, Llc Transdermal delivery of beneficial substances effected by a hostile biophysical environment
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
US12138268B2 (en) 2009-06-24 2024-11-12 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
US8604081B2 (en) 2009-06-24 2013-12-10 Strategic Science & Technologies, Llc Topical composition containing ibuprofen
US9072659B2 (en) 2009-06-24 2015-07-07 Strategic Science & Technologies, Llc Topical composition containing naproxen
EP2658551B1 (en) 2010-12-29 2020-07-01 Strategic Science & Technologies, LLC Treatment of erectile dysfunction and other indications
EP2658554A4 (en) 2010-12-29 2015-01-07 Strategic Science & Tech Llc SYSTEMS AND METHOD FOR THE TREATMENT OF ALLERGIES AND OTHER INDICATIONS
JP2016513686A (ja) * 2013-03-15 2016-05-16 ストラテジック サイエンス アンド テクノロジーズ， エルエルシー フルチカゾンの経皮製剤
WO2016112201A1 (en) * 2015-01-07 2016-07-14 Strategic Science & Technologies, Llc Techniques and systems for transdermal delivery involving treatment of psoriasis, skin cancer, and other indications
US9949915B2 (en) 2016-06-10 2018-04-24 Clarity Cosmetics Inc. Non-comedogenic and non-acnegenic hair and scalp care formulations and method for use
WO2021016236A1 (en) * 2019-07-22 2021-01-28 Novilla Pharmaceuticals, Inc. Method of remotely controlling pain

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532696A (ja) * 2004-04-19 2007-11-15 ストラテジック サイエンス アンド テクノロジーズ， エルエルシー 不利な生物物理学的環境によりもたらされる有益な物質の経皮送達
WO2010045415A2 (en) * 2008-10-16 2010-04-22 Novartis Ag Topical nsaid compositions having sensate component

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090105336A1 (en) * 2004-04-19 2009-04-23 Strategic Science & Technologies, Llc Beneficial Effects of Increasing Local Blood Flow
AU2008228764B2 (en) * 2007-03-22 2014-05-08 Berg Llc Topical formulations having enhanced bioavailability
US8604081B2 (en) * 2009-06-24 2013-12-10 Strategic Science & Technologies, Llc Topical composition containing ibuprofen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532696A (ja) * 2004-04-19 2007-11-15 ストラテジック サイエンス アンド テクノロジーズ， エルエルシー 不利な生物物理学的環境によりもたらされる有益な物質の経皮送達
WO2010045415A2 (en) * 2008-10-16 2010-04-22 Novartis Ag Topical nsaid compositions having sensate component

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023510354A (ja) * 2020-01-10 2023-03-13 ブリオリ バイオテック，エルエルシー ロフェコキシブを含有する外用組成物並びにそれを製造及び使用する方法

Also Published As

Publication number Publication date
CN103442722A (zh) 2013-12-11
EP2658553A4 (en) 2015-01-07
WO2012092525A1 (en) 2012-07-05
EP2658553A1 (en) 2013-11-06
JP2016033168A (ja) 2016-03-10
US20140004177A1 (en) 2014-01-02

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