JP2014212805A - Drug solution feeding device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a drug solution feeding device that can stably feed a drug solution stored in a syringe at a constant quantity using a tube pump in feeding the drug solution stored in the syringe and properly detects a quantity of the fed drug solution during feeding of the drug solution.SOLUTION: In the drug solution feeding device, a syringe attaching part 12 is installed on a side of a drug solution introduction part of a tube pump 10 so as to be communicated to one end of a tube 11, the syringe 20 in which the drug solution is stored is detachably attached to the syringe attaching part 12, and the drug solution stored in the syringe 20 is fed by the tube pump 10.

Description

  The present invention relates to a chemical liquid feeding apparatus using a tube pump, and more particularly to a chemical liquid feeding apparatus in which a chemical liquid stored in a syringe is fed by a tube pump.

  Conventionally, a syringe pump is generally used as a pump for feeding a chemical solution.

  In a syringe pump, generally, a plunger is slid in a syringe part for containing a chemical solution, and after sliding the plunger away from the tip of the syringe part, the chemical solution is sucked into the syringe part. With the plunger attached to the syringe part, the plunger is gradually moved to the distal end side of the syringe part, and the chemical liquid contained in the syringe part is gradually pushed out from the distal end of the syringe part to send the chemical liquid. I try to make it liquid.

  Here, in order to move the plunger gradually to the tip side of the syringe part, conventionally, the motor is rotated and the slider is slid by the gear mechanism, and the plunger is gradually moved to the tip side of the syringe part by this slider. The medical solution contained in the syringe part is gradually pushed out from the tip of the syringe part, and as shown in Patent Document 1, a contact is made to the saw-like protrusion provided on the push rod (plunger). The contact is pressed against the saw-shaped protrusion to advance the push rod, and the piston portion provided on the push rod is gradually moved to the distal end side of the syringe portion, so that the drug solution stored in the syringe portion is transferred to the syringe portion. It is shown that it is gradually pushed out from the tip.

  However, when the plunger is moved by sliding the slider with the gear mechanism by rotating the motor, the movement of the slider becomes uneven due to play or displacement between the gears in the gear mechanism, and the plunger moves at a constant speed. It is difficult to move stably, and when pressing the contact against the saw-shaped projection provided on the push rod and moving the plunger by advancing the push rod, the accuracy error of the saw-shaped projection and the pressing Due to the deformation of the contacts and the saw-like projections at the time, the movement of the push rod is uneven, and it is difficult to move the piston portion provided on the push rod by a constant amount.

  Furthermore, when the plunger is moved in the syringe part as described above, the speed at which the plunger is moved changes due to the frictional resistance between the plunger and the inner peripheral surface of the syringe part, and there is a deviation in the direction of pushing the plunger. When this occurs, the frictional resistance between the plunger and the inner peripheral surface of the syringe part changes, making it difficult to move the plunger at a constant speed.

  As a result, it becomes difficult to stably deliver a certain amount of chemical solution from the tip of the syringe part, and in particular, a small amount of chemical solution, for example, a chemical solution can be stably delivered at a rate of 1 μl / min over a long period of time. There was a problem that it would be very difficult.

  Conventionally, as shown in Patent Document 2, the chemical solution transport tube communicated with the chemical solution storage tank is mounted on a tube pump having a ring-shaped pressurizing member and an eccentric rotor, and The eccentric rotor is rotated, and the pressure contact part of the chemical solution transport tube is moved in one direction by the ring-shaped pressurizing member, so that the chemical solution in the chemical solution storage tank is fed through the chemical solution transport tube. A tube pump for injecting a chemical solution has been proposed.

  However, in the case of this chemical solution injection tube pump, it has been difficult to appropriately detect the amount of the chemical solution fed through the chemical solution transport tube during the feeding.

JP 2012-62761 A JP 2012-187365 A

  In the present invention, when feeding a chemical solution stored in a syringe, the tube pump can be used to stably feed the chemical solution stored in the syringe in a fixed amount and perform the liquid feeding. It is an object of the present invention to make it possible to appropriately detect the amount of the chemical solution being fed even during the operation.

  In the chemical solution feeding device of the present invention, in order to solve the above-described problem, a syringe mounting portion is provided on the chemical solution introducing portion side of the tube pump so as to communicate with one end of the tube, and the syringe mounting portion stores the chemical solution. The syringe was detachably attached.

  And, in the chemical solution feeding device of the present invention, the syringe containing the chemical solution is detachably attached to the syringe mounting portion provided so as to communicate with one end of the tube on the chemical solution introduction portion side of the tube pump, The chemical solution stored in the syringe is fed by the tube pump.

  Here, as the syringe, a syringe unit that contains a drug solution and a plunger that slides in the syringe unit and sucks the drug solution into the syringe unit is used, and the plunger has an axial direction. It is possible to use one provided with an air passage so as to penetrate through.

  Then, when the chemical solution is accommodated in the syringe and the syringe is attached to the syringe mounting portion, the vent of the air passage on the rear end side in the insertion direction of the plunger to be inserted into the syringe portion is blocked. In this state, the plunger is slid in the direction opposite to the insertion direction, and the chemical solution is sucked into the syringe portion, while the syringe containing the chemical solution is attached to the syringe mounting portion and the vent hole is opened. Like that. In this way, when the vent is opened in a state where the syringe containing the chemical solution is attached to the syringe mounting portion, when the chemical solution contained in the syringe is fed by the tube pump, The gas is introduced into the syringe through the air passage, preventing negative pressure in the syringe, and the chemical liquid stored in the syringe is properly fed by the tube pump without sliding the plunger. Become so.

  In addition, when the vent is opened with the syringe attached to the syringe mounting portion as described above, impurities may be mixed into the syringe through the vent path. It is preferable to provide a filter part in the middle, remove impurities by this filter part, and prevent impurities from entering the syringe through the vent.

  In addition, when a syringe is attached to the syringe mounting portion of the tube pump as described above and a liquid amount detecting means for detecting a change in the amount of the chemical in the syringe is provided, the chemical liquid is fed by the tube pump. Even during the operation, the amount of the chemical delivered by the tube pump can be detected appropriately.

  Moreover, as said tube pump, it is comprised so that a tube unit provided with the tube and the rotation pressurization member in the tube accommodating part, and the rotation apparatus unit provided with the rotation apparatus which rotates the said rotation pressurization member are separable. It is preferable to use those prepared. In this way, when sending a chemical solution from a syringe containing different chemical solutions, it is only necessary to replace the tube unit provided with the syringe mounting portion, so that the replacement work can be performed easily. Become. Further, disinfection and storage can be performed in a state where the tube unit and the rotating device unit are separated from each other, and these can be easily handled.

  As in the chemical solution feeding device of the present invention, a syringe containing a chemical solution is detachably attached to a syringe mounting portion provided so as to communicate with one end of the tube in the chemical solution introduction portion of the tube pump, When the chemical liquid stored in the syringe is fed by the tube pump, there is no need to slide the plunger with a motor, a gear mechanism, etc. in the syringe part containing the chemical liquid as in the conventional syringe pump, A certain amount of chemical solution can be sent stably.

  Further, even when the chemical liquid stored in the syringe is being fed by the tube pump, the amount of the chemical liquid being fed is properly detected by detecting a change in the liquid quantity of the chemical liquid in the syringe. Will be able to.

It is the schematic explanatory drawing which showed the state which attached the syringe to the syringe attachment part provided in the chemical | medical solution introduction part side of a tube pump in the chemical | medical solution feeding apparatus which concerns on embodiment of this invention. The tube pump used for the chemical | medical solution delivery apparatus which concerns on the embodiment is shown, (A) is a disassembled perspective view of a tube unit, (B) is a perspective view of a rotation apparatus unit. FIG. 3 is a schematic cross-sectional view showing a state where a tube unit and a rotating device unit are separated in the tube pump shown in FIG. 2. FIG. 3 is a schematic cross-sectional view showing a state where a tube unit and a rotating device unit are attached in the tube pump shown in FIG. 2. The syringe used for the chemical | medical solution feeding apparatus which concerns on embodiment of this invention is shown, (A) is a schematic front view of a syringe part, (B) is a schematic sectional drawing of a plunger. In the syringe shown in FIG. 5, it is the schematic sectional drawing which showed the state which slid a plunger in the reverse direction to an insertion direction and sucks up a chemical | medical solution in a syringe part. In the chemical solution feeding apparatus according to the embodiment of the present invention, the syringe containing the chemical solution is attached to the syringe mounting portion provided in the tube pump, and the state in which the chemical solution contained in the syringe is fed by the tube pump is shown. FIG. FIG. 5 is a schematic explanatory diagram illustrating an example in which a change in the amount of a chemical liquid in a syringe is detected by a liquid amount detection unit in the chemical liquid delivery device according to the embodiment of the present invention. It is the schematic explanatory drawing which showed the example of a change of the tube pump used for the chemical | medical solution delivery apparatus which concerns on embodiment of this invention.

  A chemical liquid delivery device according to an embodiment of the present invention will be specifically described with reference to the accompanying drawings. In addition, the chemical liquid feeding device according to the present invention is not limited to the one shown in the following embodiment, and can be implemented with appropriate modifications within a range not changing the gist thereof.

  In the chemical solution feeding apparatus in this embodiment, as shown in FIG. 1, a syringe attachment portion 12 is provided on the chemical solution introduction portion side of the tube pump 10 so as to communicate with one end of the tube 11, and this syringe attachment portion 12. In addition, the syringe 20 containing the chemical liquid L is attached.

  Here, as the tube pump 10, a tube unit 10A shown in FIG. 2 (A) and a rotating device unit 10B shown in FIG. 2 (B) are separable.

  As shown in FIG. 2A, the tube unit 10A includes a housing 13 provided with two guide recesses 13b so as to communicate with the circular tube housing portion 13a, and a tube housing portion 13a. The syringe mounting portion 12 is attached to an end portion arranged in a ring shape along the inner wall surface and led to the guide recess portion 13b on the side of the drug solution introduction portion, while the other end portion is a guide recess portion on the side of the drug solution outlet portion. The tube 11 guided to the outside of the housing 13 through 13b and the inner periphery of the tube 11 disposed in the tube housing portion 13a rotate to press the tube 11 against the inner wall surface of the tube housing portion 13a to be deformed. A rotary pressure member 14 for moving the portion in the circumferential direction, and a transparent provided on the upper surface of the housing 13 so as to close the tube housing portion 13a. It is provided with a lid 15.

  On the other hand, in the rotating device unit 10B, as shown in FIG. 2 (B), a motor (rotating device) 16 for rotating the rotating pressure member 13 provided in the tube unit 10A is provided on the base member 17. Provided

  In the tube unit 10, as the rotary pressure member 14, an eccentric rotor 14 b that rotates eccentrically by the rotation of the rotating shaft 14 a and an outer periphery of the eccentric rotor 14 b are provided to press the tube 11. One end portion of the rotary shaft 14a of the rotary pressurizing member 14 is rotatably held in the hole portion 15a provided in the lid body 15 while the rotary shaft 14a is used. The other end of the projection is projected toward the rotating device unit 10 </ b> B through the through hole 13 c provided in the housing 13.

  On the other hand, in the rotating device unit 10B, a recess for introducing the rotating shaft 14a of the rotating pressure member 14 protruding through the through hole 13c as described above to the surface of the base member 17 facing the tube unit 10A. 17a is provided, and the rotating shaft 16a of the motor 16 protrudes into the recess 17a.

  In this embodiment, the rotary shaft 14a of the rotary pressure member 14 and the rotary shaft 16a of the motor 16 are detachably connected so that the rotary pressure member 14 is rotated by the motor 16. ing.

  Here, when the rotary shaft 14a of the rotary pressure member 14 and the rotary shaft 16a of the motor 16 are detachably connected, as shown in FIG. 3, in the tube unit 10A, the rotation projected below the housing 13 is performed. While the diameter of the end portion of the rotating shaft 14a in the pressing member 14 is increased and the friction portion 14d for increasing the frictional resistance is provided on the outer periphery of the end portion, the concave portion provided in the base member 17 is provided in the rotating device unit 10B. A connecting member 18 made of a material having a high frictional resistance such as rubber having a recessed portion 18a to be fitted is provided at the end of the rotating shaft 16a of the motor 16 projecting into the motor 17a.

  And as shown in FIG. 4, it provided in the edge part of the rotating shaft 14a of the said rotation pressurization member 14 in the recessed part 18a to which the connection member 18 provided in the edge part of the rotating shaft 16a of the motor 16 fits. The friction part 14d is fitted, and the rotating shaft 16a of the motor 16 and the rotating shaft 14a of the rotary pressurizing member 14 are connected.

  Then, the motor 16 is driven in a state where the rotating shaft 16a of the motor 16 and the rotating shaft 14a of the rotary pressurizing member 14 are connected as described above, and the rotation of the rotating shaft 16a of the motor 16 is rotated. The tube 11 is accommodated in the tube by the pressing member 14c provided on the outer periphery of the eccentric rotor 14b. The eccentric rotor 14b of the rotary pressure member 14 is eccentrically rotated. The position where the inner wall surface of the portion 13a is pressed and deformed is moved in the circumferential direction.

  Further, in this embodiment, as shown in FIG. 3, in the tube unit 10A, the rotating device unit is held so that the tube unit 10A and the rotating device unit 10B are connected to a predetermined position. A positioning hole 19b for inserting the positioning pin 19a is provided on the surface of the base member 17 of the rotating device unit 10B while the positioning pin 19a made of a magnetic material is projected on the surface of the housing 13 facing the surface 10B. The magnet 19c is provided at the bottom of the positioning hole 19b.

  Then, as shown in FIG. 4, a positioning pin 19a made of a magnetic material is inserted into the positioning hole 19b, and the positioning pin 19a is inserted into the positioning hole 19b by the magnetic force of the magnet 19c provided in the positioning hole 19b. The tube unit 10A is positioned and held by the rotating device unit 10B.

  On the other hand, the syringe 20 attached to the syringe attachment part 12 in the tube pump 10 includes a hollow syringe part 21 for containing the drug solution L and an inside of the syringe part 21 as shown in FIGS. 1 and 5A, 5B. The distal end portion of the syringe portion 21 is inserted into the syringe mounting portion 12.

  Here, in the plunger 22, as shown in FIG. 5 (B), an air passage 23 that penetrates the plunger 22 in the axial direction is provided, and a filter 24 a is accommodated in the middle of the air passage 23. A filter portion 24 is provided.

  Here, when the medical solution L is accommodated in the syringe 20 and the syringe 20 is attached to the syringe attachment portion 12 of the tube pump 10, the plunger 22 inserted into the syringe portion 21 is inserted as shown in FIG. With the vent 23a of the vent path 23 at the end on the rear end side in the insertion direction closed with a finger or the like, the plunger 22 is slid in the direction opposite to the insertion direction, and the drug solution L is sucked into the syringe unit 21. The chemical solution L is accommodated in the syringe 20.

  And in the state which accommodated the chemical | medical solution L in the syringe 20 in this way, the front-end | tip part of the syringe part 21 is inserted in the syringe attachment part 12 provided in the tube pump 10, and the syringe 20 in which the chemical | medical solution L was accommodated. Is attached to the syringe attachment portion 12, and in this state, the vent 23a of the vent passage 23 closed as described above is opened.

  Next, the motor 20 in the tube pump 10 is driven to rotate the rotary pressurizing member 14 in a state where the syringe 20 in which the chemical solution L is stored in this manner is attached to the syringe mounting portion 12 of the tube pump 10. Like that.

  When the rotary shaft 14a of the rotary pressure member 14 is rotated in this way, the eccentric rotor 14b in the rotary pressure member 14 rotates eccentrically as described above, and the pressing member provided on the outer periphery of the eccentric rotor 14b. The position where the tube 11 is pressed and deformed by the inner wall surface of the tube housing portion 13a is moved in the circumferential direction by 14c, and the chemical solution L housed in the syringe 20 is introduced into the tube 11 as shown in FIG. At the same time, the chemical liquid L introduced into the tube 11 is sent in the circumferential direction through the tube 11 arranged in a ring shape with the movement of the pressing position by the pressing member 14c, and passes through the guide recess 13b on the chemical liquid outlet part side. Liquid is fed to the end of the tube 11 guided to the outside of the housing 13.

  Here, when the liquid medicine L stored in the syringe 20 is fed through the tube 11 in the tube pump 10, the gas is sucked through the air passage 23 provided in the plunger 22 of the syringe 20. At the same time, impurities contained in the gas are removed by the filter 24a in the filter portion 24 provided in the middle of the ventilation path 23, and the gas without impurities is guided into the syringe 20 and the inside of the syringe 20 becomes negative pressure. Therefore, even if the plunger 22 is not slid, the liquid medicine L stored in the syringe 20 is stably and appropriately fed by the tube pump 10 in a constant amount.

  Here, in the chemical solution feeder in this embodiment, the scale is provided in the syringe part 21 of the syringe 20 that contains the chemical solution L, and the chemical solution L is fed by the tube pump 10 as described above. The change in the amount of the chemical solution L in the syringe 20 is detected by this scale, and the amount of the chemical solution L fed by the tube pump 10 is detected.

  Further, in order to automatically detect a change in the amount of the chemical liquid L in the syringe 20, as the liquid amount detection means 30, for example, as shown in FIG. An optical sensor 32 may be provided, and light guided from the light source 31 through the syringe 20 may be detected by the optical sensor 32 to detect a change in the amount of the liquid medicine L in the syringe 20. The liquid amount detection means 30 is not particularly limited to this, and any liquid amount detection means 30 may be used as long as it can detect a change in the chemical liquid L in the syringe 20.

  Moreover, in the chemical | medical solution delivery apparatus in this embodiment, although the above tube pumps 10 were used, the tube pump 10 to be used is not limited to such a thing.

  For example, as shown in FIG. 9, a plurality of rotation pressurizing members 14 are radially arranged from the rotating body 14 e rotating by the rotating shaft 14 a on the inner peripheral side of the tube 11 through the required angle (four in the example shown in the figure). The arm 14f is protruded, and each arm 14f is provided with a pressing roller 14g for pressing the tube 11 respectively.

  In this case, when the rotating body 14e is rotated by the rotating shaft 14a, each pressing roller 14f that presses the tube 11 moves in the circumferential direction, and the liquid medicine L accommodated in the syringe 20 is communicated with the syringe 20. The chemical solution L guided from one end side of the tube 11 into the tube 11 between the pressure rollers 14g and thus guided into the tube 11 between the pressure rollers 14g is sequentially sent in the circumferential direction, and the chemical solution deriving unit The liquid is fed to the end of the tube 11 guided to the outside of the housing 13 through the guide recess 13b on the side.

DESCRIPTION OF SYMBOLS 10 Tube pump, 10A tube unit, 10B Rotating device unit 11 Tube 12 Syringe attachment part 13 Housing, 13a Tube accommodating part, 13b Guide recessed part, 13c Through-hole 14 Rotation pressure member, 14a Rotating shaft, 14b Eccentric rotor, 14c Press Member, 14d Friction part, 14e Rotating body, 14f Arm, 14g Pressure roller 15 Lid, 15a Hole part 16 Rotating device, 16a Rotating shaft 17 Base member, 17a Recessed part 18 Connecting member, 18a Recessed part 19a Positioning pin, 19b Positioning Hole, 19c Magnet 20 Syringe 21 Syringe part 22 Plunger 23 Air passage, 23a Vent 24 Filter part, 24a Filter L Chemical liquid

Claims (6)

  A chemical liquid feeding apparatus, wherein a syringe mounting portion is provided on the side of a chemical liquid introducing portion of a tube pump so as to communicate with one end of a tube, and a syringe containing a chemical liquid is detachably mounted on the syringe mounting portion.   2. The liquid medicine delivery device according to claim 1, wherein the syringe includes a syringe part that stores the chemical liquid, and a plunger that slides in the syringe part and sucks up the chemical liquid into the syringe part. A chemical solution feeding device, wherein an air passage is provided so as to penetrate in an axial direction.   3. The chemical liquid feeding device according to claim 2, wherein the plunger is slid in the direction opposite to the insertion direction in a state in which the vent of the ventilation path on the rear end side in the insertion direction of the plunger to be inserted into the syringe portion is closed. The chemical solution feeding device is characterized in that the chemical solution is sucked into the syringe part, and the vent is opened in a state where the syringe containing the chemical solution is attached to the syringe mounting part.   4. The chemical liquid feeding apparatus according to claim 2 or 3, wherein a filter portion is provided in the middle of the air passage in the plunger.   In the chemical solution feeding device according to any one of claims 1 to 4, a change in the amount of the chemical solution in the syringe is detected in a state where the syringe is attached to the syringe attachment portion of the tube pump. A chemical solution feeding device comprising a liquid amount detecting means.   6. The chemical liquid delivery device according to claim 1, wherein the tube pump includes a tube unit including a tube and a rotary pressurizing member in a tube housing portion, and the rotary pressurization. A chemical solution feeding device characterized in that it is configured to be separable from a rotating device unit including a rotating device for rotating a member.

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