JP2014171752A - Radiotherapy apparatus and radiotherapy system - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a radiotherapy apparatus capable of stopping irradiation before generation of a body motion of a patient and a radiotherapy system.SOLUTION: The radiotherapy apparatus includes: a body motion brain wave pattern storage part for storing a body motion brain wave pattern which is unique to an analyte indicating an instruction of a body motion generated before the analyte moves his/her body; an irradiation part for irradiating the analyte with radiation rays; a brain wave pattern acquisition part for acquiring a brain wave pattern unique to the analyte during the irradiation; and an irradiation determination part for stopping the irradiation when the brain wave pattern acquired coincides with the body motion brain wave pattern stored.

Description

  Embodiments described herein relate generally to a radiation therapy apparatus and a radiation therapy system.

  In radiotherapy, image data is generated by imaging at the time of treatment planning, and treatment plan data is generated based on the image data. When performing treatment, image data obtained by imaging is generated immediately before the treatment, and treatment with radiation is performed along the treatment plan data generated previously.

  In such treatment with radiation, since exposure is accompanied, efforts are made to minimize radiation exposure in consideration of the burden on the patient's physical condition.

  For example, in a predetermined X-ray imaging apparatus, there is disclosed an X-ray imaging apparatus that detects a patient's body movement when imaging a patient with X-rays and moves an X-ray imaging unit following the detected body movement. (See Patent Document 1).

JP 2011-160978 A

  However, in the case of an X-ray imaging apparatus that moves the X-ray imaging unit following the movement of the patient, the body movement is generated in the patient and the deviation due to the body movement is corrected.

  For this reason, when body movement occurs in a patient, X-rays are irradiated to a part not in the treatment plan, and until the X-ray imaging unit follows the body movement, the part to be irradiated with X-rays is irradiated. There was a problem that I could not do it.

  That is, when body motion occurs in the patient, X-rays are irradiated to any position (part) in the treatment plan immediately after the body motion, and until the X-ray imaging unit follows the body motion. The cancer cells could not be irradiated and normal cells could be exposed.

  The radiotherapy apparatus according to the present embodiment includes a body motion electroencephalogram pattern storage unit that stores a body motion electroencephalogram pattern specific to the subject indicating an instruction of body motion that occurs before the subject moves the body, and radiation to the subject. Irradiation unit that irradiates, EEG pattern collection unit that collects EEG patterns unique to the subject during irradiation, and irradiation that stops radiation irradiation when the collected electroencephalogram pattern matches the stored body motion EEG pattern A determination unit.

1 is an external view showing a part of a radiotherapy system to which a radiotherapy apparatus according to a first embodiment is applied. BRIEF DESCRIPTION OF THE DRAWINGS The block diagram which shows the whole radiotherapy system to which the radiotherapy apparatus which concerns on 1st Embodiment is applied. The block diagram which shows the function of the radiotherapy system of 1st Embodiment. In the radiotherapy system according to the first embodiment, an operation of a mis-irradiation prevention process that is performed when a console collects a patient's brain wave pattern during irradiation and the collected brain wave pattern matches a body motion brain wave pattern is shown. Flowchart. The block diagram which shows the whole radiotherapy system to which the radiotherapy apparatus which concerns on 2nd Embodiment is applied. The block diagram which shows the whole radiotherapy system to which the radiotherapy apparatus which concerns on 3rd Embodiment is applied. The flowchart which showed the operation | movement of the electroencephalogram pattern registration process which a console collects a patient's electroencephalogram pattern and registers the collected electroencephalogram pattern as a body motion electroencephalogram pattern in the radiotherapy system of 3rd Embodiment.

  A radiotherapy apparatus according to this embodiment will be described with reference to the accompanying drawings. In addition, although this embodiment demonstrates the case where a radiotherapy apparatus is applied to a radiotherapy system, this embodiment is not limited to this. For example, the radiotherapy apparatus according to the present embodiment can be used as a single treatment apparatus, or can be applied to other systems.

  In addition, since the radiotherapy apparatus according to the present embodiment relates to the control of the apparatus itself, the components that perform the control may be configured integrally with the radiotherapy apparatus, or provided in a separate console or the like. It may be done. Therefore, in the present embodiment, a case where a component that performs control is provided in a separate console will be described as an example.

(First embodiment)
FIG. 1 is an external view showing a part of a radiation therapy system 1 to which a radiation therapy apparatus 50 according to the first embodiment is applied. FIG. 2 is a configuration diagram showing the entire radiation therapy system 1 to which the radiation therapy apparatus 50 according to the first embodiment is applied.

  1 and 2 show a radiation treatment system 1 as a first embodiment. The radiotherapy system 1 includes a console 10 (FIG. 2), an X-ray CT apparatus (imaging apparatus) 20, a bed apparatus 30, a treatment plan apparatus 40 (FIG. 2), and a radiotherapy apparatus (linac: treatment plan data). (Radiotherapy apparatus for performing treatment by irradiating radiation) 50).

  As shown in FIG. 1, the X-ray CT apparatus 20, the bed apparatus 30, and the radiotherapy apparatus 50 are usually installed in an examination room. On the other hand, the console 10 is usually installed in a control room adjacent to the examination room (not shown in FIG. 1). The treatment planning device 40 is installed outside the examination room or the control room (not shown in FIG. 1).

  The treatment planning device 40 may be installed in the control room, or may be a device integrated with the console 10. The X-ray CT apparatus 20 is an example of an apparatus used as an imaging apparatus. Other typical examples include an MRI (magnetic resonance imaging) apparatus and an X-ray apparatus.

  As shown in FIG. 2, the console 10 of the radiation therapy system 1 is configured based on a computer, and can communicate with a network such as a hospital backbone LAN (local area network) (not shown). The console 10 is mainly composed of basic hardware such as a CPU (central processing unit) 11, a main memory 12, an image memory 13, an HDD (hard disc drive) 14, an input device 15, and a display device 16. .

  The CPU 11 is a control device having a configuration of an integrated circuit (LSI) in which an electronic circuit made of a semiconductor is enclosed in a package having a plurality of terminals. When a command is input by operating the input device 15 by an operator such as a doctor, the CPU 11 executes a program stored in the main memory 12. Alternatively, the CPU 11 is read from a program stored in the HDD 14, a program transferred from the network and installed in the HDD 14, or a recording medium mounted on a recording medium drive (not shown in FIG. 2) and installed in the HDD 14. The program thus loaded is loaded into the main memory 12 and executed.

  The CPU 11 is interconnected to each hardware component constituting the console 10 via a bus as a common signal transmission path. Further, the console 10 may include a recording medium drive.

  The main memory 12 is a storage device having a configuration having elements such as a ROM (read only memory) and a RAM (random access memory). The main memory 12 stores IPL (initial program loading), BIOS (basic input / output system) and data, and is used for temporary storage of the work memory and data of the CPU 11.

  The image memory 13 is a storage device that stores slice data as two-dimensional image data, treatment plan volume data as three-dimensional image data, and volume data just before treatment.

  The HDD 14 is a storage device having a configuration in which a metal disk coated or vapor-deposited with a magnetic material is incorporated in a non-detachable manner. The HDD 14 is a storage device that stores a program (including an OS (operating system) in addition to an application program) installed in the console 10 and data. Also, it is possible to cause the OS to provide a graphical user interface (GUI) capable of performing basic operations by the input device 15 by using graphics frequently for displaying information on the display device 16 for an operator such as an operator. it can.

  The input device 15 is a pointing device that can be operated by an operator, and an input signal according to the operation is sent to the CPU 11.

  The display device 16 includes an image composition circuit (not shown), a video random access memory (VRAM), a display, and the like. The image synthesizing circuit generates synthesized data obtained by synthesizing character data of various parameters with image data. The VRAM develops the composite data as display image data to be displayed on the display. The display is configured by a liquid crystal display, a cathode ray tube (CRT), or the like, and sequentially displays display image data as a display image.

  The console 10 controls operations of the X-ray CT apparatus 20, the bed apparatus 30, and the radiation therapy apparatus 50. Further, the console 10 generates projection data by performing logarithmic conversion processing and correction processing (preprocessing) such as sensitivity correction on the raw data input from the DAS 24 of the X-ray CT apparatus 20, and generates projection data based on the projection data. In addition, slice data as two-dimensional image data and volume data as three-dimensional image data are generated.

  The X-ray CT apparatus 20 (FIG. 2) of the radiotherapy system 1 images a region including a treatment site in order to display image data of the region including a treatment site such as cancer or tumor of the patient O (subject). . The X-ray CT apparatus 20 includes an X-ray tube 21 as a radiation source, an aperture 22, an X-ray detector 23, a DAS (data acquisition system) 24, a rotating unit 25, a high voltage supply device 26, an aperture driving device 27, and a rotational drive. A device 28 and an imaging controller 29 are provided.

  The X-ray tube 21 generates a braking X-ray by causing an electron beam to collide with a metal target according to the tube voltage supplied from the high voltage supply device 26, and the X-ray is directed toward the X-ray detector 23. Irradiate. Fan beam X-rays and cone beam X-rays are formed by X-rays emitted from the X-ray tube 21.

  The diaphragm 22 adjusts the irradiation range of the X-rays emitted from the X-ray tube 21 by the diaphragm driving device 27. That is, the X-ray irradiation range can be changed by adjusting the aperture of the diaphragm 22 by the diaphragm driving device 27.

  The X-ray detector 23 is a matrix, that is, a two-dimensional array type X-ray detector 23 (also referred to as a multi-slice detector) having a plurality of channels in the channel direction and a plurality of rows in the slice direction. It is. The X-ray detection element of the X-ray detector 23 detects X-rays emitted from the X-ray tube 21.

  The DAS 24 amplifies the transmission data signal detected by each X-ray detection element of the X-ray detector 23 and converts it into a digital signal. Output data from the DAS 24 is supplied to the console 10 via the imaging controller 29.

  The rotating unit 25 integrally holds the X-ray tube 21, the diaphragm 22, the X-ray detector 23, and the DAS 24. The rotating unit 25 can rotate around the patient O together with the X-ray tube 21, the diaphragm 22, the X-ray detector 23, and the DAS 24 with the X-ray tube 21 and the X-ray detector 23 facing each other. It is configured. A direction parallel to the rotation center axis of the rotating unit 25 is defined as a z-axis direction, and a plane orthogonal to the z-axis direction is defined as an x-axis direction and a y-axis direction.

  The high voltage supply device 26 supplies power necessary for X-ray irradiation to the X-ray tube 21 under the control of the imaging controller 29.

  The diaphragm driving device 27 has a mechanism for adjusting the irradiation range of the diaphragm 22 in the X-ray slice direction under the control of the imaging controller 29.

  The rotation driving device 28 has a mechanism for rotating the rotating unit 25 so that the rotating unit 25 rotates around the hollow portion while maintaining the positional relationship under the control of the imaging controller 29.

  The imaging controller 29 includes a CPU and a memory. The imaging controller 29 controls the X-ray tube 21, the X-ray detector 23, the DAS 24, the high voltage supply device 26, the aperture driving device 27, the rotation driving device 28, etc. Run a scan.

  The bed apparatus 30 (FIG. 2) of the radiation therapy system 1 includes a top board 33, a top board drive apparatus 32, and a bed controller 39.

  The top plate 33 can place the patient O thereon. The top plate driving device 32 is controlled by the bed controller 39 to move the top plate 33 up and down along the y-axis direction, the mechanism to move the top plate 33 back and forth along the z-axis direction, and the top plate 33. and a mechanism that rotates the y-axis direction as an axis.

  The bed controller 39 includes a CPU and a memory. The couch controller 39 controls the top board driving device 32 and the like, thereby executing a scan with the operation of the X-ray CT apparatus 20. In addition, the bed controller 39 controls the top board driving device 32 and the like, thereby executing radiation therapy with the operation of the radiation therapy device 50.

  The treatment planning device 40 of the radiation treatment system 1 is a treatment plan for performing radiation treatment by the radiation treatment device 50 on the basis of slice data and volume data imaged using the X-ray CT device 20 and generated by the console 10. Generate data. Under the control of the console 10 based on the treatment plan data generated by the treatment planning device 40, the radiation treatment device 50 irradiates the medical site of the patient O with radiation. The treatment planning apparatus 40 is configured on the basis of a computer, and can communicate with a network such as a hospital backbone LAN (not shown). The treatment planning device 40 is mainly composed of basic hardware such as a CPU 41, a main memory 42, a treatment plan memory 43, an HDD 44, an input device 45, and a display device 46. The CPU 41 is interconnected to each hardware component constituting the treatment planning apparatus 40 via a bus as a common signal transmission path. The treatment planning device 40 may include a recording medium drive.

  The configuration of the CPU 41 is equivalent to the configuration of the CPU 11 of the console 10. When an instruction is input by operating the input device 45 by an operator, the CPU 41 executes a program stored in the main memory 42. Alternatively, the CPU 41 may be a program stored in the HDD 44, a program transferred from the network and installed in the HDD 44, or a program read from a recording medium installed in a recording medium drive (not shown) and installed in the HDD 44. Are loaded into the main memory 42 and executed.

  The configuration of the main memory 42 is the same as the configuration of the main memory 12 of the console 10. The main memory 42 stores IPL, BIOS, and data, and is used for temporary storage of the work memory and data of the CPU 41.

  The treatment plan memory 43 is a storage device that stores treatment plan data. The configuration of the HDD 44 is the same as the configuration of the HDD 14 of the console 10. The input device 45 is equivalent to the configuration of the input device 15 of the console 10. The display device 46 is equivalent to the configuration of the display device 16 of the console 10.

  The treatment planning device 40 obtains the position of the treatment site and the shape of the treatment site of the patient O based on the image data generated by the X-ray CT apparatus 20, and the radiation (X-ray, electron beam, Neutron beam, proton beam, heavy particle beam, etc.), its energy, and irradiation field. In the present embodiment, any radiation such as an X-ray or an electron beam can be applied.

  The radiotherapy apparatus 50 of the radiotherapy system 1 can generally generate MV (Mega electron Volt) grade radiation. The radiation therapy apparatus 50 installs a diaphragm (collimator) at a radiation generation port, and realizes an irradiation shape and a dose distribution based on the treatment plan by the diaphragm. In recent years, a multi-leaf collimator (MLC) that can form a dose distribution corresponding to a complicated tumor shape by a plurality of movable leaves as a diaphragm is often used. The radiation therapy apparatus 50 adjusts the radiation dose by the irradiation field formed by the diaphragm, and eliminates or reduces the treatment site of the patient O. The combination of the X-ray CT apparatus 20, the bed apparatus 30, and the radiation therapy apparatus 50 is called “linac-CT”.

  The radiation therapy apparatus 50 includes a radiation source 51 as a radiation source, an aperture 52, an arm unit 55, a high voltage supply device 56, an aperture drive device 57, a rotation drive device 58, and a treatment controller 59.

  The radiation source 51 generates radiation according to the tube voltage supplied from the high voltage supply device 56.

  The diaphragm 52 adjusts the irradiation range of the radiation irradiated from the radiation source 51 by the diaphragm driving device 57. That is, by adjusting the aperture of the diaphragm 52 by the diaphragm driving device 57, the radiation irradiation range can be changed.

  The arm unit 55 holds the radiation source 51 and the diaphragm 52 together. The arm portion 55 is configured so that the radiation source 51 and the diaphragm 52 can be rotated around the patient O as a unit.

  The high voltage supply device 56 supplies the radiation source 51 with electric power necessary for irradiation with radiation under the control of the treatment controller 59.

  The diaphragm driving device 57 has a mechanism for adjusting the radiation range of the diaphragm 52 under the control of the treatment controller 59.

  The rotation driving device 58 has a mechanism for rotating the arm portion 55 so as to rotate around the connection portion between the arm portion 55 and the support portion under the control of the treatment controller 59.

  The treatment controller 59 includes a CPU and a memory. The treatment controller 59 controls the radiation source 51, the high voltage supply device 56, the diaphragm drive device 57, and the like according to the treatment plan data generated by the treatment planning device 40, thereby performing treatment with the operation of the bed device 30. Radiation is executed.

  FIG. 3 is a block diagram showing functions of the radiation therapy system 1 of the present embodiment.

  As the CPU 11 of the console 10 and the CPU 41 of the treatment planning apparatus 40 execute the program, the radiotherapy system 1 includes an imaging execution unit 61, an image data generation unit 62, a treatment plan data generation unit 63, as shown in FIG. It functions as an interface unit 64, a body motion electroencephalogram pattern storage unit 65, an electroencephalogram pattern collection unit 66, an irradiation determination unit 67, and a treatment execution unit 68. Note that all or part of the components 61 to 68 of the radiotherapy system 1 may be provided as hardware in the radiotherapy system 1.

  The imaging execution unit 61 of the console 10 controls the operations of the imaging controller 29 of the X-ray CT apparatus 20 and the bed controller 39 of the bed apparatus 30 to image a region including the treatment site of the patient O for a treatment plan. Has a function to be executed. Further, the imaging execution unit 61 controls the operations of the imaging controller 29 of the X-ray CT apparatus 20 and the bed controller 39 of the bed apparatus 30 and includes the treatment site of the patient O after the treatment plan, for example, immediately before the treatment. It has a function to execute imaging of a region.

  The image data generation unit 62 of the console 10 performs processing such as image reconstruction processing on transmission data (captured data) acquired by the X-ray CT apparatus 20 by the imaging execution unit 61, and slice data as two-dimensional image data. It has the function to generate. The image data generation unit 62 has a function of generating volume data as three-dimensional image data based on slice data corresponding to a plurality of slices. Specifically, the image data generation unit 62 generates slice data by imaging for treatment planning, and generates volume data (treatment plan volume data) VP for treatment planning by the treatment planning apparatus 40.

  Further, the image data generation unit 62 generates slice data by imaging immediately before treatment by the radiation therapy apparatus 50, and generates volume data (Q data immediately before treatment) VQ immediately before treatment. The volume data VP and VQ generated by the image data generation unit 62 are respectively stored in a storage device such as the image memory 13.

  The treatment plan data generation unit 63 of the treatment plan apparatus 40 shown in FIG. 3 considers the body contour of the patient O, the affected area, and the like based on the treatment plan volume data VP stored in the image memory 13. It has a function of generating treatment plan data by setting irradiation conditions such as the number of gates and radiation intensity and setting a treatment plan. When generating the treatment plan data, the treatment plan data generation unit 63 sets a necessary area, for example, an outline SP of an OAR (organ at risk) that is not desired to be irradiated with radiation, based on the treatment plan volume data VP.

  For example, the treatment plan data generation unit 63 sets the OAR contour SP via the interface unit 64. The OAR contour SP set by the treatment plan data generating unit 63 is three-dimensional position information. When setting the OAR contour SP, the treatment plan data generation unit 63 may set only one OAR contour SP1, or may set a plurality of OAR contours SP1, SP2,. Further, the treatment plan data generation unit 63 may set a comparison point (isocenter) when generating treatment plan data.

  Note that the contour SP of the required region set by the treatment plan data generation unit 63 is not limited to the OAR contour SP. The contour SP of the required region set by the treatment plan data generation unit 63 may be a contour SP of a PTV (planning target volume) as a treatment site.

  The treatment plan data generation unit 63 is described as generating treatment plan data based on the treatment plan volume data VP generated by the X-ray CT apparatus 20 constituting the radiation treatment system 1, but in that case It is not limited. The treatment plan data generation unit 63 may generate treatment plan data based on treatment plan volume data generated by an imaging device outside the radiation treatment system 1. The treatment plan data generated by the treatment plan data generation unit 63 is stored in a storage device such as the treatment plan memory 43.

  The interface unit 64 of the treatment planning device 40 causes the display device 46 to display a display image based on the treatment plan volume data VP, and selects the OAR contour SP on the display image via the input device 45 operated by the operator. It is an interface such as a GUI that makes it possible.

  In the radiotherapy system 1 according to the present embodiment, an electroencephalogram measuring instrument 70 is connected to the console 10.

  The electroencephalogram measuring instrument 70 is an electroencephalogram measuring instrument for measuring the brain wave of the patient O. The electroencephalograph 70 only needs to be able to measure an electroencephalogram. For example, the electroencephalogram measuring instrument 70 can measure an electroencephalogram by attaching several tens of electrodes to the head of the patient O, or a device using a so-called biofeedback method. You may make it measure an electroencephalogram.

  The body motion electroencephalogram pattern storage unit 65 of the console 10 is a storage device that stores a patient motion body electroencephalogram pattern indicating an instruction of body motion that occurs before the patient O moves the body. Here, the body motion electroencephalogram pattern refers to an electroencephalogram pattern that is presumed to acquire the body motion of the patient O in advance, analyze the relationship with the body motion, and then cause the body motion. Further, it is assumed that the body motion electroencephalogram pattern storage unit 65 is provided in a part of the HDD 14.

  The electroencephalogram pattern collection unit 66 of the console 10 has a function of collecting an electroencephalogram pattern unique to the patient. In the present embodiment, the brain waves of the patient O measured by the electroencephalograph 70 are collected as an electroencephalogram pattern.

  The irradiation determination unit 67 of the console 10 irradiates the patient O with radiation by the radiation source 51 of the radiotherapy apparatus 50, collects the brain wave pattern of the patient O during the irradiation, and the collected brain wave pattern of the patient O is the body. A determination function is provided to stop radiation irradiation when the body motion brain wave pattern stored in the motion brain wave pattern storage unit 65 matches the body motion brain wave pattern.

  For example, the irradiation determination unit 67 performs pattern matching processing between the collected brain wave patterns of the patient O and the plurality of body motion brain wave patterns stored in the body motion brain wave pattern storage unit 65, and the plurality of body motion brain wave patterns are obtained. If any of the body motion electroencephalogram patterns matches at a predetermined ratio (for example, 80%) or more, it is determined that the electroencephalogram pattern matches the body motion electroencephalogram pattern. If it is determined that the electroencephalogram pattern and the body motion electroencephalogram pattern match, the irradiation determination unit 67 causes the treatment execution unit 68 to stop the irradiation of the radiation from the radiation source 51 of the radiation therapy apparatus 50.

  The treatment execution unit 68 of the console 10 controls the operation of the treatment controller 59 of the radiation treatment apparatus 50 and the bed controller 39 of the bed apparatus 30 to execute the treatment of the treatment site of the patient O or stop the radiation irradiation. Have

(Incorrect irradiation prevention treatment)
Next, in the radiation therapy system 1 of this embodiment, the operation of the erroneous irradiation prevention process processed by the console 10 will be described.

  FIG. 4 is a radiation treatment system 1 according to the present embodiment. The console 10 collects the brain wave pattern of the patient O during irradiation, and the erroneous irradiation prevention process is performed when the collected brain wave pattern matches the body motion brain wave pattern. It is the flowchart which showed the operation | movement of the process. In FIG. 4, reference numerals with numbers added to ST indicate steps in the flowchart.

  First, when the patient O is placed on the couch 33 of the couch device 30 of the radiotherapy system 1, the radiotherapy system 1 controls the operation of the couch controller 39 of the couch device 30, and the X-ray CT is performed on the couchtop 33. Insert into the opening of the device 20. Next, as shown in FIG. 4, the radiotherapy system 1 controls the operation of the imaging controller 29 of the X-ray CT apparatus 20 and performs imaging of a region including the treatment site of the patient O for the treatment plan ( Step ST001).

  Next, the radiotherapy system 1 performs processing such as image reconstruction processing on the transmission data acquired by the X-ray CT apparatus 20 in step ST001 to generate slice data as two-dimensional image data, and slices corresponding to a plurality of slices Based on the data, treatment plan volume data VP as three-dimensional image data is generated (step ST002).

  The treatment plan volume data VP generated in step ST002 is stored in a storage device such as the image memory 13 (step ST003).

  The radiation therapy system 1 considers the body contour and affected area of the patient O based on the treatment plan volume data VP stored in the image memory 13 in step ST003, and irradiates the irradiation direction, the number of gates, the radiation intensity, and the like. By setting conditions and setting a treatment plan, treatment plan data is generated (step ST004). In step ST004, the radiotherapy system 1 can set an OAR contour SP as a required region based on the treatment plan volume data VP.

  The treatment plan data generated in step ST004 is stored in a storage device such as the treatment plan memory 43 (step ST005).

  When the imaging of the region including the treatment site of the patient O is completed in step ST001, the radiation therapy system 1 controls the operation of the bed controller 39 of the bed apparatus 30 and opens the top plate 33 to the opening of the X-ray CT apparatus 20. Evacuate part. Next, the patient O is lowered from the top plate 33 of the bed apparatus 30 of the radiation therapy system 1.

  Thereafter, immediately before the treatment by the radiation therapy apparatus 50 is performed, the patient O is placed on the top plate 33 of the bed apparatus 30 of the radiation therapy system 1, and the radiation therapy system 1 operates the bed controller 39 of the bed apparatus 30. And the top plate 33 is inserted into the opening of the X-ray CT apparatus 20. Next, the radiation therapy system 1 controls the operation of the imaging controller 29 of the X-ray CT apparatus 20 and executes imaging of a region including the treatment site of the patient O immediately before the treatment (step ST006).

  The radiotherapy system 1 performs processing such as image reconstruction processing on the transmission data acquired by the X-ray CT apparatus 20 in step ST006 to generate slice data as two-dimensional image data, and obtains slice data corresponding to a plurality of slices. Based on this, volume data VQ immediately before treatment as three-dimensional image data is generated (step ST007).

  The pre-treatment volume data VQ generated in step ST007 is stored in a storage device such as the image memory 13 (step ST008). The radiotherapy system 1 sets the OAR contour SQ corresponding to the OAR contour SP stored in the treatment plan memory 43 based on the immediately preceding treatment volume data VQ stored in the image memory 13 in step ST008. Can do.

  Next, the radiation treatment system 1 controls the operation of the treatment controller 59 of the radiation treatment apparatus 50 to perform treatment of the treatment site of the patient O (step ST009).

  When radiation therapy for the patient O is started, the electroencephalogram pattern collection unit 66 of the radiation therapy system 1 performs a patient-specific electroencephalogram pattern via the electroencephalograph 70 during the radiation therapy for the treatment site of the patient O. Are collected (step ST010).

  The irradiation determination unit 67 of the radiotherapy system 1 acquires the electroencephalogram pattern collected by the electroencephalogram pattern collection unit 66, and the acquired electroencephalogram pattern matches the body motion electroencephalogram pattern stored in the body motion electroencephalogram pattern storage unit 65. Is determined (step S011). If the acquired electroencephalogram pattern matches the body motion electroencephalogram pattern stored in the body motion electroencephalogram pattern storage unit 65 (Yes in step ST011), the irradiation determination unit 67 controls the treatment execution unit 68. Then, the treatment by the radiation therapy apparatus 50 is stopped (step S012).

  On the other hand, when the acquired electroencephalogram pattern does not coincide with the body motion electroencephalogram pattern stored in the body motion electroencephalogram pattern storage unit 65 (No in step ST011), it is determined whether or not to end the treatment in step S012. When an input to end the treatment is made from the input device 15 (Yes in step S013), the treatment of the patient O is finished.

  On the other hand, if the input device 15 does not input to end the treatment (No in step S013), the CPU 11 of the console 10 proceeds to step S009 and continues the treatment of the patient O. .

  As described above, in this embodiment, the CPU 11 of the console 10 in the radiation therapy system 1 performs radiation when the brain wave pattern of the patient O collected during radiation therapy matches the body motion brain wave pattern in steps S010 and S011. Radiation irradiation is stopped by controlling the treatment controller 59 of the treatment device 50 and the bed controller 39 of the bed device 30.

  Thereby, since the radiotherapy system 1 to which the radiotherapy apparatus 50 according to the present embodiment is applied can stop the irradiation of the radiation before the patient O moves to the body, the radiation therapy system 1 can be applied to a part not included in the treatment plan. There is no radiation, and there is no risk of exposure of normal cells.

(Second Embodiment)
In the first embodiment, the radiation therapy system 1 collects the brain wave pattern of the patient O during the radiation therapy, and stops the radiation irradiation when the collected brain wave pattern matches the patient-specific body motion brain wave pattern. It was like that.

  In the second embodiment, in addition to the first embodiment, a body electromyographic pattern storage unit that stores a patient-specific body electromyogram pattern, and a myoelectric pattern collection unit that collects a patient-specific electromyogram pattern; Are further provided.

  FIG. 5 is a configuration diagram showing an entire radiation therapy system 1A to which the radiation therapy apparatus according to the second embodiment is applied. The radiotherapy system 1A of the second embodiment shown in FIG. 5 is different from the radiotherapy system of the first embodiment shown in FIG. 3 in that the body motion myoelectric pattern storage unit 69, the myoelectric sensor 71, and And a myoelectric pattern collection unit 72.

  The body motion myoelectric pattern storage unit 69 stores a patient specific body motion myoelectric pattern for contracting muscles generated before the patient O moves the body. The body motion myoelectric pattern storage unit 69 is stored in the HDD 14A (equivalent to the HDD 14 (FIG. 2 and the like)) in the same manner as the body motion electroencephalogram pattern storage unit 65.

  The myoelectric sensor 71 is a sensor that acquires a myoelectric signal of the patient O. Specifically, it is assumed that the sensor is attached to the skin surface of the patient O and acquires the myoelectric signal of the patient O, but the present embodiment is not limited to this. That is, any form that can acquire the myoelectric signal of the patient O may be used, and the myoelectric signal may be acquired by an apparatus using a method called biofeedback.

  Here, the muscle is composed of many fibers called muscle fibers, and contracts by receiving signals from the brain through motor nerves. When this muscle contraction occurs, a potential is generated from the muscle, this potential is called a myoelectric potential, and this myoelectric information is called a myoelectric signal.

  The myoelectric pattern collection unit 72 collects patient-specific myoelectric patterns from the myoelectric sensor 71. This myoelectric pattern means a patient-specific motion pattern indicated by the myoelectric signal.

  In addition, in the radiation therapy system 1A of the second embodiment shown in FIG. 5, the CPU 11A equivalent to the CPU 11 (FIG. 2 and the like) executes the program so that an irradiation determination unit 67A is provided.

  In addition to the function of the irradiation determination unit 67 shown in FIG. 3, the irradiation determination unit 67A is further irradiated with radiation by the radiation source 51 (FIG. 2) of the radiation therapy apparatus 50, and the radiation is being irradiated. A determination function for collecting the myoelectric pattern of the patient O and stopping radiation irradiation when the collected myoelectric pattern of the patient O matches the body electromyographic pattern stored in the body motion myoelectric pattern storage unit 69. I have.

  For example, the irradiation determination unit 67A performs pattern matching processing between the collected myoelectric patterns of the patient O and the plurality of body motion myoelectric patterns stored in the body motion myoelectric pattern storage unit 69, and the plurality of body motions. If any of the myoelectric patterns matches a body motion myoelectric pattern at a predetermined ratio (for example, 80%) or more, it is determined that the myoelectric pattern matches the body motion myoelectric pattern. When it is determined that the myoelectric pattern and the body motion myoelectric pattern match, the irradiation determination unit 67A causes the treatment execution unit 68 to stop the irradiation of radiation from the radiation source 51 of the radiation therapy apparatus 50.

  Thus, in the second embodiment, in addition to the function of collecting the electroencephalogram pattern of the first embodiment and stopping the radiation irradiation when the collected electroencephalogram pattern matches the body motion electroencephalogram pattern, A function of collecting the electrical pattern and stopping the radiation irradiation when the collected myoelectric pattern coincides with the body motion myoelectric pattern is provided in a superimposed manner.

  That is, the first function of determining radiation irradiation by the electroencephalogram pattern of the first embodiment and the second function of determining radiation irradiation by the myoelectric pattern of the second embodiment are provided. By combining the function and the second function, the following three patterns (functions) are provided.

  The first pattern is a pattern for stopping radiation irradiation when the electroencephalogram pattern matches the body motion electroencephalogram pattern and the myoelectric pattern matches the body motion myoelectric pattern. Next, the second pattern is a pattern for stopping radiation irradiation when the electroencephalogram pattern matches the body motion electroencephalogram pattern or when the myoelectric pattern matches the body motion electroencephalogram pattern. The third pattern is a pattern in which radiation irradiation is stopped by at least one of the determination by the electroencephalogram pattern (first function) and the determination by the myoelectric pattern (second function).

  Thereby, in 2nd Embodiment, compared with 1st Embodiment, before a patient's O body motion arises, since irradiation of a radiation can be stopped more reliably, in addition, in a treatment plan, There is no possibility that radiation will be irradiated to a site that is not present, and there is no risk of exposure of normal cells.

  Note that the operation of the irradiation determination unit 67A in the flowchart is that the process of changing the electroencephalogram pattern determined by the irradiation determination unit 67 to the myoelectric pattern in step ST011 (FIG. 4) is added to the irradiation determination unit 67. The operation is almost the same. Therefore, explanation is omitted. The electroencephalogram pattern may be adopted instead of the electroencephalogram pattern determined by the irradiation determination unit 67, and the electroencephalogram pattern described in the first embodiment may be changed to the myoelectric pattern.

(Third embodiment)
In the first embodiment and the second embodiment, an electroencephalogram pattern or myoelectric pattern is collected, and the electroencephalogram pattern or myoelectric pattern of the patient O acquired during radiotherapy is a body motion electroencephalogram pattern or body electromyography. When the pattern coincides with the pattern, the irradiation is stopped.

  In the third embodiment, a body motion pattern registration unit for registering in advance a patient-specific electroencephalogram pattern or myoelectric pattern in the body motion electroencephalogram pattern storage unit or the body motion myoelectric pattern storage unit is further provided.

  FIG. 6 is a configuration diagram showing the entirety of a radiation therapy system 10B to which the radiation therapy apparatus according to the third embodiment is applied. The radiotherapy system 10B of the third embodiment shown in FIG. 6 is different from the radiotherapy system 10A of the second embodiment shown in FIG. 5 in that the irradiation determination unit 67A includes a body motion pattern registration unit 73. It is a point which becomes the structure of the irradiation determination part 67B.

  The body motion pattern registration unit 73 has a function of registering a patient-specific brain wave pattern in the body motion brain wave pattern storage unit 65 in advance. The body motion pattern registration unit 73 has a function of registering not only the electroencephalogram pattern but also the myoelectric pattern in the body motion myoelectric pattern storage unit 69 in advance. Since the body movement pattern registration unit 73 is an arbitrary component, at least one of the electroencephalogram pattern or the myoelectric pattern may be registered.

  The body motion pattern registration unit 73 is configured to be included in a part of the function of the irradiation determination unit 67B, but the function of the body motion pattern registration unit 73 of the present embodiment is limited to this. It may be configured anywhere.

(Brain pattern registration process)
Next, the operation of the electroencephalogram pattern registration process processed by the console 10B in the radiation therapy system 1B of the present embodiment will be described. In this embodiment, a case where an electroencephalogram pattern is registered will be described as an example, but the same applies to a case where a myoelectric pattern is registered.

  FIG. 7 is a flowchart showing an operation of an electroencephalogram pattern registration process in which the console 10B collects an electroencephalogram pattern of the patient O and registers the collected electroencephalogram pattern as a body motion electroencephalogram pattern in the radiotherapy system 1B of the present embodiment. is there. In FIG. 7, reference numerals with numbers added to ST indicate steps in the flowchart.

  The console 10B shown in FIG. 6 executes the electroencephalogram pattern registration process of the body movement pattern registration unit 73 when the CPU 11B executes the program. In this electroencephalogram pattern registration process, the operator, for example, raises the right hand, raise the left hand, raise the right foot, and raise the left foot. Please request actions such as "Please twist your body to the right.", "Please twist your body to the left."

  In the third embodiment, the console 10B requests the patient O to act, and measures the electroencephalogram pattern before the patient O's body moves (step ST101). Specifically, the body motion pattern registration unit 73 collects an electroencephalogram pattern corresponding to the action from the electroencephalograph 70 via the electroencephalogram pattern collection unit 66 for the action requested by the operator.

  In this electroencephalogram pattern registration process, it is possible to increase the probability of stopping radiation irradiation in the radiation therapy apparatus 50 by requesting a plurality of actions and collecting many electroencephalogram patterns. In addition, even if the same operation is performed, a plurality of electroencephalogram patterns can be collected by causing the same operation to be performed multiple times. Therefore, image processing of an electroencephalogram pattern (for example, pattern matching) can be performed by increasing the number of samples. ) Can be improved in accuracy.

  Then, the body motion pattern registration unit 73 registers the collected brain wave patterns as body motion brain wave patterns in the body motion brain wave pattern storage unit 65 (step ST102). Specifically, the body motion pattern registration unit 73 stores the collected brain wave patterns in the body motion brain wave pattern storage unit 65 as patient-specific body motion brain wave patterns.

  As described above, in the third embodiment, the body movement pattern registration unit 73 performs an electroencephalogram pattern registration process in which an electroencephalogram pattern is registered, whereby the collected electroencephalogram pattern is generated before the patient O moves the body. It can be registered in the body motion electroencephalogram pattern storage unit 65 as a patient-specific body motion electroencephalogram pattern indicating a motion instruction.

  Since this electroencephalogram pattern and myoelectric pattern are different for each patient O, the timing immediately before treatment, for example, the timing of generating volume data VQ immediately before treatment (before step ST006) or just before treatment (before step ST009) It is desirable to obtain a characteristic analysis by acquiring the brain wave and myoelectric signal of the patient O.

  Although several embodiments of the present invention have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the spirit of the invention. These embodiments and their modifications are included in the scope and gist of the invention, and are also included in the invention described in the claims and the equivalents thereof.

  Further, in the embodiment of the present invention, each step of the flowchart shows an example of processing that is performed in time series in the order described. The process to be executed is also included.

1, 1A, 1B Radiation therapy system 10, 10A, 10B Console 10, 11A, 11B CPU
20 X-ray CT device 29 Imaging controller 30 Bed device 33 Top plate 39 Bed controller 40 Treatment planning device 50 Radiation treatment device 59 Treatment controller 61 Imaging execution unit 62 Image data generation unit 63 Treatment plan data generation unit 64 Interface unit 65 Body motion brain wave Pattern storage unit 66 Electroencephalogram pattern collection units 67, 67 A, 67 B Irradiation determination unit 68 Treatment execution unit 69 Body motion myoelectric pattern storage unit 70 Electroencephalogram measuring instrument 71 Myoelectric sensor 72 Myoelectric pattern collection unit 73 Body motion pattern registration unit

Claims (7)

A body motion electroencephalogram pattern storage unit that stores a body motion electroencephalogram pattern specific to the subject indicating an instruction of body motion that occurs before the subject moves the body;
An irradiation unit for irradiating the subject with radiation;
An electroencephalogram pattern collection unit for collecting the electroencephalogram pattern specific to the subject during irradiation of the radiation;
When the collected electroencephalogram pattern matches the stored body motion electroencephalogram pattern, an irradiation determination unit that stops the irradiation of the radiation,
A radiotherapy apparatus comprising: A body motion myoelectric pattern storage unit for storing a body motion myoelectric pattern for contracting muscles generated before the subject moves the body; and A myoelectric pattern collection unit that collects during irradiation,
The irradiation determination unit
The radiotherapy apparatus according to claim 1, wherein the radiation irradiation is stopped when the collected myoelectric pattern matches the stored body motion myoelectric pattern. A body motion electroencephalogram pattern registration unit for registering in advance the subject electroencephalogram pattern in the body motion electroencephalogram pattern storage unit;
The body motion electroencephalogram pattern registration unit
The subject electroencephalogram pattern indicating an instruction of body motion that occurs before the subject moves the body is stored in the body motion electroencephalogram pattern storage unit as the body motion electroencephalogram pattern unique to the subject. 3. A radiotherapy apparatus according to 2. A body motion myoelectric pattern registration unit for registering in advance in the body motion electroencephalogram pattern storage unit the myoelectric pattern unique to the subject;
The body motion myoelectric pattern registration unit
A subject-specific myoelectric pattern for collecting muscles generated before the subject moves a body is stored in the body motion myoelectric pattern storage unit as the body motion myoelectric pattern unique to the subject. Item 3. A radiotherapy apparatus according to Item 2. The irradiation determination unit
The radiation according to any one of claims 1 to 4, wherein in the comparison between the collected electroencephalogram pattern and the stored body motion electroencephalogram pattern, it is determined whether or not they match by pattern matching processing indicated by an electroencephalogram image. Therapeutic device. A body motion electroencephalogram pattern storage unit that stores a body motion electroencephalogram pattern specific to the subject indicating an instruction of body motion that occurs before the subject moves the body;
An irradiation unit for irradiating the subject with radiation;
An electroencephalogram pattern collection unit for collecting the electroencephalogram pattern specific to the subject during irradiation of the radiation;
When the collected electroencephalogram pattern matches the stored body motion electroencephalogram pattern, an irradiation determination unit that stops irradiation of the radiation,
A radiation therapy system comprising: A myoelectric pattern storage unit for storing a subject's body motion myoelectric pattern for contracting muscles generated before the subject moves the body;
An irradiation unit for irradiating the subject with radiation;
An electromyographic pattern collection unit for collecting the myoelectric pattern unique to the subject during the irradiation of the radiation;
When the collected myoelectric pattern matches the stored body motion myoelectric pattern, an irradiation determining unit that stops the irradiation of the radiation,
A radiotherapy apparatus comprising:

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