JP2014070062A5 - - Google Patents
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- JP2014070062A5 JP2014070062A5 JP2012219526A JP2012219526A JP2014070062A5 JP 2014070062 A5 JP2014070062 A5 JP 2014070062A5 JP 2012219526 A JP2012219526 A JP 2012219526A JP 2012219526 A JP2012219526 A JP 2012219526A JP 2014070062 A5 JP2014070062 A5 JP 2014070062A5
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- KWYUFKZDYYNOTN-UHFFFAOYSA-M potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- RCOVTJVRTZGSBP-UHFFFAOYSA-N 4-(chloromethyl)benzoyl chloride Chemical compound ClCC1=CC=C(C(Cl)=O)C=C1 RCOVTJVRTZGSBP-UHFFFAOYSA-N 0.000 description 2
- QGJOPFRUJISHPQ-UHFFFAOYSA-N carbon bisulphide Chemical compound S=C=S QGJOPFRUJISHPQ-UHFFFAOYSA-N 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- MIJDSYMOBYNHOT-UHFFFAOYSA-N 2-(ethylamino)ethanol Chemical compound CCNCCO MIJDSYMOBYNHOT-UHFFFAOYSA-N 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- LAKYXBYUROTWBI-UHFFFAOYSA-N bis(benzylsulfanyl)methanethione Chemical class C=1C=CC=CC=1CSC(=S)SCC1=CC=CC=C1 LAKYXBYUROTWBI-UHFFFAOYSA-N 0.000 description 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- -1 hydroxyethyl Chemical group 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxyl anion Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 239000001184 potassium carbonate Substances 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002194 synthesizing Effects 0.000 description 1
- HIZCIEIDIFGZSS-UHFFFAOYSA-L trithiocarbonate Chemical compound [S-]C([S-])=S HIZCIEIDIFGZSS-UHFFFAOYSA-L 0.000 description 1
Description
特開２００７−２３０９４７には、ジベンジルトリチオカーボネート誘導体の合成について記載されている（特許文献１）。例えば、下記式（１）のビス[４−[Ｎ−エチル−２−(ヒドロキシエチル)アミノカルボニル]−ベンジル]トリチオカーボネートは、下記式（３）のＮ−エチル−エタノールアミンと下記一般式（２）の４−クロロメチルベンゾイルクロライドとを縮合させて下記一般式（４）のアミド誘導体水酸化物とする。ついで、この一般式（４）の水酸基をアセチル基で保護した後に、二硫化炭素／炭酸カリウムで縮合させ、次いで水酸化カリウムで脱アセチル化することによる全４工程の反応により一般式（１）で表される化合物を全収率７２％で得ている。 In JP 2007-23094 7 is described for the synthesis of dibenzyl trithiocarbonate derivatives (Patent Document 1). For example, bis [4- [N-ethyl-2- (hydroxyethyl) aminocarbonyl] -benzyl] trithiocarbonate of the following formula (1) is composed of N-ethyl-ethanolamine of the following formula (3) and the following general formula: The amide derivative hydroxide represented by the following general formula (4) is condensed with 4-chloromethylbenzoyl chloride (2). Next, after protecting the hydroxyl group of the general formula (4) with an acetyl group, it is condensed with carbon disulfide / potassium carbonate, and then deacetylated with potassium hydroxide to give a general formula (1). In an overall yield of 72%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012219526A JP5918678B2 (en) | 2012-10-01 | 2012-10-01 | Method for producing dibenzyltrithiocarbonate derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012219526A JP5918678B2 (en) | 2012-10-01 | 2012-10-01 | Method for producing dibenzyltrithiocarbonate derivative |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014070062A JP2014070062A (en) | 2014-04-21 |
| JP2014070062A5 true JP2014070062A5 (en) | 2015-08-13 |
| JP5918678B2 JP5918678B2 (en) | 2016-05-18 |
Family
ID=50745597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012219526A Active JP5918678B2 (en) | 2012-10-01 | 2012-10-01 | Method for producing dibenzyltrithiocarbonate derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5918678B2 (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5016829B2 (en) * | 2006-03-02 | 2012-09-05 | 日本テルペン化学株式会社 | Dibenzyltrithiocarbonate derivative, process for producing the same and polymer using the same |
-
2012
- 2012-10-01 JP JP2012219526A patent/JP5918678B2/en active Active
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