JP2014042750A - Component administration device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a component administration device having excellent handleability.SOLUTION: A component administration device 10 includes an electrode device 15 that includes a first electrode 21 and a second electrode 22 disposed apart from each other, an absorber 40 disposed so as to face both of the first electrode and the second electrode, and a component housing body 50 that houses a component that can be absorbed by the absorber. The housing body is disposed such that at least one portion thereof is positioned between the electrode device and the absorber.

Description

  The present invention relates to a component administration device for administering a component.

  For example, as disclosed in Patent Document 1 and Patent Document 2, iontophoresis is known in which components are transdermally administered using electric energy. Patent Document 1 and Patent Document 2 disclose self-electromotive component administration devices that utilize the difference in standard electrode potential between electrodes. As described in the column of the effect of the invention of Patent Document 2, according to the self-electromotive-type component administration device that does not use an external power supply, it is stable for a long time as compared with a component administration device that uses an external power supply. Ingredient administration can be realized.

  The self-electromotive type component administration device has a pair of electrodes electrically connected by electric wiring, and a component holder disposed between at least one electrode and the skin. The component holder holds components to be administered to the skin. In recent years, in order to realize more efficient component administration, the component holder may be disposed at a position extending between the pair of electrodes and facing both the pair of electrodes.

Japanese Patent Laid-Open No. 03-016573 JP 60-203270 A

  However, when the component holder that holds the component to be administered transdermally is in contact with and electrically connected to the pair of electrodes, the component holder, the pair of electrodes, and the wiring that connects the pair of electrodes In between, a self-electromotive type closed circuit is formed and energization starts. When energization starts, the electrode gradually deteriorates and finally energization stops. Therefore, the component holder is stored or stored in a state of being separated from the pair of electrodes. When the component administration device is used, the component holding body is electrically connected to a pair of separately stored electrodes and disposed at a site where the component is to be administered.

  However, it is troublesome to handle a component holding body that holds a component that is normally liquid in use. Further, when the positioning accuracy between the component holding body and the electrode is lowered, the contact area between the component holding body and the electrode is reduced, and the energization efficiency is lowered. In particular, such a problem becomes more prominent in a component administration device that is used by a user to administer a component to himself / herself, such as administration of a cosmetic liquid.

  The present invention has been made in consideration of the above points, and an object of the present invention is to provide a component administration device with excellent handling properties.

The component administration device according to the present invention comprises:
An electrode device having first and second electrodes spaced apart from each other, and a connection element for electrically connecting the first electrode and the second electrode;
An absorber disposed to face both the first electrode and the second electrode;
A component container containing a component that can be absorbed by the absorber,
The container is arranged so that at least a part thereof is located between the electrode device and the absorber or at least a part thereof is located inside the absorber.

In the component administration device according to the present invention,
The container has a bag breaking portion that can be broken by pressurization,
The container may be arranged such that at least the bag breaking portion is located between the electrode device and the absorber or inside the absorber.

  In the component administration device according to the present invention, the component container may be bonded to at least one of the absorber and the electrode device.

  In the component administration device according to the present invention, the component container may be removable between the electrode device and the absorber or from the inside of the absorber.

  In the component administration device according to the present invention, in the region between the first electrode and the second electrode, the insulation is located between the connection element and the absorber and separates the connection element and the absorber from each other A body may be provided.

The component administration device according to the present invention further comprises a sheet-like support,
On one side of the support, a metal layer forming the connection element is provided,
The first electrode layer and the second electrode layer are provided apart from each other on the opposite side of the metal layer from the support, and the first electrode layer and the second electrode layer are the metal layer. Electrically connected to the
An insulator is provided on a surface between the first electrode and the second electrode of the metal layer,
The absorber may be spaced apart from the metal layer via the insulator and extend between a position facing the first electrode and a position facing the second electrode.

  In the component administration device according to the present invention, the electrical device further includes an insulating support provided on a side of the first electrode, the connection element, and the second electrode opposite to the absorber side. You may do it.

  According to the present invention, the handleability of the component administration device can be effectively improved.

FIG. 1 is a view for explaining an embodiment of the present invention and is a cross-sectional view showing a component administration device. FIG. 2 is an exploded perspective view schematically showing the component administration device of FIG. FIG. 3 is a view for explaining a method of using the component administration device of FIG. FIG. 4 is a diagram for explaining a modification of the component administration device, and is a plan view showing the component administration device with the electrode device removed. FIG. 5 is a diagram corresponding to FIG. 4 and is a diagram for explaining another modification of the component administration device. FIG. 6 is a diagram corresponding to FIG. 1 and for explaining still another modification of the component administration device.

  Hereinafter, an embodiment of the present invention will be described with reference to the drawings. In the drawings attached to the present specification, for the sake of illustration and ease of understanding, the scale, the vertical / horizontal dimension ratio, and the like are appropriately changed and exaggerated from those of the actual product.

  1 to 3 are diagrams for explaining an embodiment of the present invention. Among these, FIG. 3 has shown the component administration apparatus 10 in use condition, and FIG. 1 has shown the component administration apparatus 10 before use. On the other hand, FIG. 2 is an exploded perspective view showing the component administration device before use.

  As shown in FIG. 1, the component administration device 10 includes an electrode device 15 including a first electrode 21 and a second electrode 22 that are spaced apart from each other, and a first electrode 21 and a second electrode 22 of the electrode device 15. It has the absorber 40 arrange | positioned so that both may be faced, and the component container 50 which accommodated the component which can be absorbed by the absorber 40. FIG. The electrode device 15 has a connection element 25 for electrically connecting the first electrode 21 and the second electrode 22.

  As shown in FIG. 3, when the component administration device 10 is used, the component is released from the component container 50 and absorbed by the absorber 40. And in this component administration apparatus 10, it is hold | maintained at the absorber 40 in the position which faces each electrode 21 and 22 by the self-electromotive force resulting from the difference in the standard electrode potential of the 1st electrode 21 and the 2nd electrode 22. Components are introduced into the skin. In other words, the component administration device 10 is used for iontophoresis that is placed on the skin and transdermally administers the components. Hereafter, each component of the component administration apparatus 10 is demonstrated in order.

  First, the electrode device 15 of the component administration device 10 will be described. As described above, the electrode device 15 includes the first electrode 21 and the second electrode 22, and the connection element 25. As shown in FIG. 1, the connection element 25 extends between the first electrode 21 and the second electrode 22 and is electrically connected to the first electrode 21 and the second electrode 21. The component administration device 10 shown in FIG. 1 further includes an insulator 30 located between the connecting element 25 and the absorber 40 in a region between the first electrode 21 and the second electrode 22. . In addition, as shown in FIG. 1, the component administration device 10 includes an insulating support 35 provided on the opposite side of the first electrode 21, the connecting element 25, and the second electrode 22 from the absorber 40 side. In addition.

  The support 35 functions as a layer that can support the first electrode 21 and the second electrode 22 and the connection element 25 in the electrode device 15. The support 35 can be produced using a resin sheet such as polyethylene terephthalate. The illustrated support 35 is formed in a substantially rectangular shape as shown in FIG. In the example shown in FIG. 1, the connecting element 25 is formed as a metal layer 26 laminated on the surface of the support 35 on the absorber 40 side. The metal layer 26 can be produced on the support 35 by, for example, transfer or vapor deposition of a metal foil. The first electrode 21 and the second electrode 22 are formed on the metal layer 26 that forms the connection element 25. Each of the first electrode 21 and the second electrode 22 can be made of a metal foil. In the example shown in FIG. 1, the first electrode 21 and the second electrode 22 are formed as metal foils that are bonded and electrically connected to the metal layer 26 via conductive adhesives 21 a and 22 a, respectively. .

  In this case, “adhesion” is used as a concept including “adhesion”. Therefore, for example, “adhesive” is a concept including “adhesive”, and “adhesiveness” is a concept including “adhesive”.

  By the way, the first electrode 21 contains the first metal as a main component (that is, in the largest proportion), and the second electrode 22 has the second metal different from the first metal as the main component (that is, the most). In a large proportion). The standard electrode potential of the first metal is lower than the standard electrode potential of the second metal.

  Therefore, in the use state shown in FIG. 3, the first electrode 21 containing the first metal as the main component and the second electrode 22 containing the second metal as the main component absorbed and held the connection element 25 and the components. When connected by the path of the absorber 40 and at least one of the skin, a current flows due to self-electromotive force caused by a difference in standard electrode potential. In the component administration device 10 described here, electrons flow from the first electrode 21 through the connecting element 25 to the second electrode 22, and further electrons are emitted from the second electrode 22 toward the absorber 40. As indicated by an arrow in FIG. 3, the current I flows from the second electrode 22 through the connection element 25 to the first electrode 21 in the opposite direction to the electrons.

  In addition, as a 1st metal which makes the main component of the 1st electrode 21, zinc, aluminum, magnesium etc. can be used, for example. Therefore, the first electrode 21 can be composed of zinc, aluminum, magnesium, alloys of these metals, oxides of these metals, semiconductors using these metals, or the like. On the other hand, as the second metal constituting the main component of the second electrode 22, for example, gold, silver, platinum or the like can be used.

  Next, the absorber 40 will be described. As shown in FIG. 1, the absorber 40 extends from a position facing the first electrode 21 to a position facing the second electrode 22. The absorber 40 is at least partially in contact with each of the first electrode 21 and the second electrode 22. The absorber 40 is configured to be able to absorb the component released from the component container 50. The absorber 40 is formed of an insulating material, and does not electrically connect the first electrode 21 and the second electrode 22 in a state in which no component is absorbed. As an example, the absorber 40 may be formed of a porous material such as a sponge that can absorb and hold a liquid component, or a woven or non-woven fabric.

  The absorber 40 is preferably bonded to the electrode device 15 in a partial region of the facing surface. Here, bonding means that the absorber 40 and the electrode device 15 are connected directly or indirectly by, for example, a tape or an adhesive, and includes bonding as an example. In this case, the absorber 40 is maintained at a predetermined position with respect to the electrode device 15, and the absorber 40 is positioned at a position facing the first electrode 21 and the second electrode 22. In addition, as shown in FIG. 3, the component administration device 10 comes into contact with the skin via the absorber 40. For this reason, it is preferable that the absorber 40 has a certain degree of adhesiveness, the absorber 40 adheres to the skin, and the component administration device 10 is held on the skin.

  Next, the component container 50 will be described. The ingredient container 50 is intended to contain the ingredient to be administered to the skin until the ingredient administration device 10 is used. In addition, the component accommodated in the component container 50 can be made into a chemical | medical agent component, cosmetics, etc., for example. In particular, it is preferable that an ionizable component is included as the component held in the component holding body 40.

  The component container 50 is arranged such that at least a part thereof is located between the electrode device 15 and the absorber 40 or at least a part thereof is located inside the absorber 40. With such an arrangement of the component container 50, the component released from the component container 50 can be absorbed by the absorber 40. In the example shown in FIGS. 1 to 3, the entire component container 50 is positioned between the electrode device 15 and the absorber 40. The component container 50 is bonded to the absorbent body 40 through an adhesive means such as an adhesive or an adhesive tape (not shown), and is also bonded to the electrode device 15 through an adhesive means 42 such as an adhesive or an adhesive tape. Yes. That is, in the example of FIGS. 1 to 3, the electrode device 15 and the absorber 40 can be held at positions positioned with respect to each other via the component container 50.

  The component container 50 has a bag breaking portion 55 that can be broken by pressurization. Preferably, the component container 50 can avoid unintentional breakage during handling such as transportation of the component administration device 10 and can be easily broken by the pressing force of the user's finger of the component administration device 10. Has been. The component container 50 shown in FIGS. 1 to 3 is produced by sealing a film material. More specifically, the component container 50 is formed by folding a single film and sealing it from three directions. The sealing can be realized by heat sealing, for example. And the sealing part 51 formed can form the bag breaking part 55 of the component container 50 by adjusting the heating temperature at the time of sealing, pressurizing force, heating time, pressurization time, etc.

  The component administration device 10 configured as described above is stored and stored in a state where the component is accommodated in the component container 50 before use. That is, the component administration device 10 is stored and stored in a state where the absorber 40 does not absorb the component, and the first electrode 21 and the second electrode 22 are electrically connected via the absorber 40. There is nothing. Therefore, in the storage state of the component administration device 10 in which the absorber 40 does not absorb the component, the first electrode 21 and the second electrode 22 are electrically connected only by the connection element 25. For this reason, the circuit 12 is cut off and no current flows between the first electrode 21 and the second electrode 22.

  In the component administration device 10 as described above, the component container 50 is made of a material having a desirable property with respect to the component, for example, a UV light barrier, in order to prevent evaporation and alteration of the component housed in the component container 50. It is preferable that it is comprised from the material which has the property and oxygen barrier property. In addition, the component administration device 10 is stored and stored in a packaging material, and the packaging material is made of a material having desirable properties for the component, for example, a material having a UV light barrier property or an oxygen barrier property. It is also preferable.

  Next, the operation of the component administration device 10 having the above configuration will be described.

  First, the component container 50 is pressurized. For example, the component container 50 is pressurized by the user pressing the electrode device 15 and the absorber 40 toward each other with his / her hand, and the component container 50 accommodates the component. The body 50 is broken. Due to the bag breaking of the component container 50, the components that have been stored in the component container 50 are released from the component container 50 and absorbed by the absorber 40.

  Next, the component administration device 10 is arranged so that the absorber 40 contacts the skin of the site where the component is to be administered. However, without being limited to this order, the bag breaking of the component container 50 may be performed after the component administration device 10 is placed on the skin, or in parallel with the placement of the component administration device 10 on the skin. May be implemented.

  By the way, the absorber 40 is positioned in advance at a position in contact with the first electrode 21 and the second electrode 22 of the electrode device 15, and preferably in the positional relationship via an adhesive means 42 such as an adhesive or an adhesive tape. It is fixed. Therefore, the first electrode 21 and the second electrode 22 are conducted through the component absorbed by the absorber 40. That is, the first electrode 21 and the second electrode 22 are electrically connected via the connection element 25 and also electrically connected via the component absorbed by the absorber 40. Thereby, the closed circuit 12 which electrically connects the absorber 40, the 1st electrode 21, the 2nd electrode 22, and the connection element 25 comes to be formed. The energization in the closed circuit 12 starts due to the difference in standard electrode potential between the first electrode 21 and the second electrode 22. Furthermore, when the absorber 40 that has absorbed the components of the component administration device 10 comes into contact with the skin, the closed circuit is formed by electrically connecting the skin, the first electrode 21 and the second electrode 22, and the connecting element 25. 14 is formed, and energization in the closed circuit 14 starts.

The standard electrode potential of the first metal that is the main component of the first electrode 21 is lower than the standard electrode potential of the second metal that is the main component of the second electrode 22. Therefore, electrons flow from the first electrode 21 through the connection element 25 to the second electrode 22, and further electrons are emitted from the second electrode 22 toward the absorber 40. Accordingly, as shown in FIG. 3, in the region facing the second electrode 22, the negatively charged ionized component X ⁻ out of the components absorbed and held by the absorber 40 is introduced into the skin. On the contrary, in the region facing the first electrode 21, the positively charged ionized component Y ⁺ out of the components absorbed and held by the absorber 40 is introduced into the skin. In this way, iontophoresis is performed by the component administration device 10.

In addition, with the introduction of the ionized components X ⁻ and Y ^{+ from} the absorber 40 to the skin, the liquid held in the absorber 40 flows from the absorber 40 toward the skin. And the component which is not ionized by this liquid flow is also administered from the absorber 40 to skin.

  As shown in FIG. 3, the current I flows from the second electrode 22 through the connection element 25 to the first electrode 21 in the opposite direction to the electrons. That is, current flows in the skin constituting the circuit 14 from the first electrode 21 side to the second electrode 22 side. At the same time, a current flows from the first electrode 21 side to the second electrode 22 side in the absorber 40 that absorbs and holds the components constituting the circuit 12. In this way, the absorber 40 that can absorb the components extends so as to face both the first electrode 21 and the second electrode 22 that are arranged to be separated from each other. A component can be introduced directly under the electrode 22, and energization can be performed both on the surface and inside of the skin where the component is to be introduced. According to such a method, it is possible to effectively introduce the component absorbed in the absorber 40 into the skin in a short time. That is, iontophoresis can be performed very effectively.

  From the viewpoint of more stable and safer self-electromotive iontophoresis, there is a difference in standard electrode potential between the first metal of the first electrode 21 and the second metal of the second electrode 22. It is preferably 0.3 V or more and 3 V or less, and more preferably 0.5 V or more and 1.5 V or less.

  By the way, in the above component administration apparatus 10, the absorber 40 which will absorb a component is previously positioned with respect to the electrodes 21 and 22 of the electrode device 15. Therefore, unlike the conventional component administration apparatus, it is not necessary to perform a complicated treatment such as positioning the component holder packaged separately from the electrode device with respect to the electrode of the electrode device immediately before use. From this point, the component administration device 10 described here is very excellent in handleability. Moreover, since the absorber 40 and the electrodes 21 and 22 of the electrode device 15 are positioned accurately in advance in the component administration device 10 described here, the introduction of the component absorbed and held by the absorber 40 is stabilized. Can be implemented.

  On the other hand, the component to be administered to the skin is accommodated in the component container 50 before use of the component administration device 10 and is not absorbed by the absorber 40. Then, by breaking the component container 50 and releasing the component from the component container 50 to the absorber 40, the absorber 40 that has absorbed the component, the first electrode 21 and the second electrode 22, for the first time, A self-electromotive type closed circuit 12 formed by electrically connecting the connecting element 25 is formed. By using this component container 50, it is possible to effectively prevent energization between the first electrode 21 and the second electrode 22 before using the component administration device 10.

  That is, while the absorber 40 that absorbs and holds the component with respect to the electrodes 21 and 22 of the electrode device 15 is positioned in advance, the energization before the use of the component administration device 10 is prevented, and the intended use In the state, the component introduction can be carried out for a long time. Therefore, stable component introduction can be performed for a long time.

  In addition, the component container 50 that stores the components before use is arranged so that at least a part thereof is located between the electrode device 15 and the absorber 40 or at least a part thereof is located inside the absorber 40. ing. According to such a component administration device 10, compared with the case where a sachet provided apart from the electrode device and the absorber is used as the component container, the component is absorbed by the absorber 40 and the component administration device 10 is Making it ready for use can be easily performed.

  In particular, the illustrated component container 50 has a bag breaking portion 55 that can be broken by pressurization, and the bag breaking portion 55 is disposed between the electrode device 15 and the absorber 40. Therefore, the component can be absorbed by the absorbent body 40 and the component administration device 10 can be used simply by pressurizing the component container 50 directly or indirectly. In addition, in the example shown by FIGS. 1-3, the component container 50 is arrange | positioned between the electrode device 15 and the absorber 40 as a whole. Therefore, when the component administration device 10 is placed on the skin and used, the component container 50 does not deteriorate the usability.

  However, the component container 50 is provided between the electrode device 15 and the absorber 40 so as not to reduce the contact area between the absorber 40 that has absorbed the component and the electrodes 21 and 22 of the electrode device 15. It is preferable that the first electrode 21 and the second electrode 22 are disposed so as not to face each other.

  In addition, even if the circuit 12 is not formed, the first electrode 21 and the second electrode 22 may emit electrons simply by contacting the ionic component. On the other hand, according to the component administration device 10, the absorber 40 does not absorb the ionic component before use. Therefore, it is possible to effectively prevent the first electrode 21 and the second electrode 22 from being deteriorated due to contact with the components before use.

  Note that various modifications can be made to the above-described embodiment. Hereinafter, an example of modification will be described with reference to the drawings. In the following description and the drawings used in the following description, the same reference numerals as those used for the corresponding parts in the above embodiment are used for the parts that can be configured in the same manner as in the above embodiment. A duplicate description is omitted.

  In embodiment mentioned above, although the example in which the component container 50 was arrange | positioned as a whole between the electrode device 15 and the absorber 40 was shown, it is not restricted to this. As shown in FIG. 4, only a part of the component container 50 may be disposed between the electrode device 15 and the absorber 40. Hereinafter, the specific example shown in FIG. 4 will be described. In FIG. 4 and FIG. 5 described later, the positions of the first electrode 21 and the second electrode 22 are indicated by two-dot chain lines, but the illustration of the electrode device 15 is omitted.

  In the example shown in FIG. 4, the component container 50 is formed as a sachet having an outer contour defined by a seal portion 51. The component container 50 includes a main portion 50b having a relatively large volume and an elongated introduction portion 50a extending from the main portion 50b. The introduction part 50 a is disposed between the electrode device 15 and the absorber 40, and the main part 50 b is exposed from the electrode device 15 and the absorber 40.

  The seal portion 51 that defines the component container 50 is divided into a weak seal portion 52a that is more likely to break and a strong seal portion 52b that is less likely to break depending on the strength of the seal. The weak seal portion 52 a forms the bag breaking portion 55 of the component container 50. Note that the strength of the seal portion 51 can be adjusted according to the processing conditions at the time of manufacturing the seal portion 51 as already mentioned. In the example of FIG. 4, the seal portion 51 that defines the main portion 50b is a strong seal portion 52b, and the seal portion 51 that defines the introduction portion 50a is a weak seal portion 52a.

  According to such a component administration apparatus 10 shown in FIG. 4, by pressing the exposed main portion 50 b of the component container 50, the introduction portion 50 a positioned between the electrode device 15 and the absorber 40 is pressed. Thus, the component container 50 can be broken. Therefore, the component container 50 can be operated directly to break the component container 50 very easily.

  In the above-described embodiment, the example in which the component container 50 is bonded to at least one of the absorber 40 and the electrode device 15 has been described. However, the present invention is not limited to this. For example, in the example shown in FIG. 4, the component container 50 is not joined to either the absorber 40 or the electrode device 15. In the example shown in FIG. 4, the component container 50 can be removed from between the electrode device 15 and the absorber 40. According to such a component administration device 10, the component container 50 in which the bag breakage and the component release have been completed can be removed from the electrode device 15 and the absorber 40. Thereby, it becomes possible to avoid that the component container 50 deteriorates usability when the component is introduced into the skin using the component administration device 10.

  In the example shown in FIG. 4, a pair of bonding means (for example, an adhesive or an adhesive tape) 42 for bonding the absorber 40 and the electrode device 15 is provided. An introduction portion 50 a that extends linearly of the component container 50 is disposed between the pair of adhesives 42. With this configuration, the component container 50 is held between the electrode device 15 and the absorber 40 by a certain restraining force, and slides in a predetermined direction with respect to the electrode device 15 and the absorber 40. It is possible.

  Furthermore, in embodiment mentioned above, although the bag-breaking part 55 of the component container 50 showed the example formed by reducing a seal strength, it is not restricted to this. For example, as shown in FIG. 5, the stress is concentrated when the bag breaking portion 55 pressurizes the component administration device 10 instead of reducing the sealing strength or in addition to reducing the sealing strength. The concentration unit 53 may be defined. As another example, the bag breaking portion 55 may be defined by changing the seal width.

  Note that. Also in the component administration apparatus 10 shown in FIG. 5, only a part of the component container 50 is disposed between the electrode device 15 and the absorber 40, and the other part of the component container 50 is the electrode device 15 and It is exposed from the absorber 40. A first adhesive means (for example, an adhesive or an adhesive tape) 42a is provided between the electrode device 15 and the absorber 40, and the electrode device 15 and the absorber 40 are positioned by the first adhesive means 42a. Can be kept in a relationship.

  On the other hand, the component container 50 is provided with a second bonding means (for example, an adhesive or an adhesive tape) 42b, and either the electrode device 15 or the absorber 40 is provided via the second bonding means 42b. It is glued. However, the adhesive force of the second adhesive means 42b is relatively weak and weaker than the adhesive force of the first adhesive means 42a. Therefore, after the component container 50 is broken and the components are released from the component container 50, the component container 50 is held by the electrode device 15 and the electrode device 15 and the part exposed from the electrode device 15 and the absorber 40. By pulling out from the absorbent body 40, the second adhesive means 42b can be peeled off or the second adhesive means 42b can be peeled off to remove the component container 50 from the component administration device 10.

  Furthermore, in the above-described embodiment and its modification, the example in which at least a part of the component container 50 is located between the electrode device 15 and the absorber 40 has been described, but the present invention is not limited thereto. As an example, as shown in FIG. 6, at least a part of the component container 50 may be disposed inside the absorber 40. In such a form, the component container 50 can be broken by pressurizing the component container 50 between the absorbers 40. When the component container 50 is broken, the components stored in the component container 50 are stably absorbed by the absorber 40. Therefore, even in a form in which at least a part of the component container 50 is located inside the absorber 40, the same action as in the above-described form in which at least a part of the component container 50 is located between the electrode device 15 and the absorber 40. There is an effect.

  That is, while the absorber 40 that absorbs and holds the component with respect to the electrodes 21 and 22 of the electrode device 15 is positioned in advance, the energization before the use of the component administration device 10 is prevented, and the intended use In the state, the component introduction can be carried out for a long time. Therefore, stable component introduction can be performed for a long time. In addition, since the component container 50 that stores the components before use is arranged so that at least a part of the component container 50 is located inside the absorber 40, a sachet provided apart from the electrode device and the absorber is provided. Compared to the case of using as a component container, it is possible to easily make the component administration device 10 usable by causing the absorber 40 to absorb the component.

  The absorbent body 40 may be formed of a porous material in which a housing portion (for example, a cut) in which the component housing body 50 can be housed, or a woven or non-woven fabric. Further, the absorbent body 40 is formed of two porous materials arranged opposite to each other, a woven or non-woven fabric, or the like, and is absorbed between the two porous materials or a woven or non-woven fabric. The body 40 may be arranged. In this example, it is preferable that two porous materials, a woven fabric or a non-woven fabric are joined to each other so that the component container 50 does not escape from the inside of the absorber 40.

  Further, in the example shown in FIG. 6, the example in which the component container 50 is disposed inside the absorbent body 40 as a whole is shown, but only a part of the component container 50 including the bag breaking portion 55 is shown. Alternatively, it may be arranged inside the absorber 40. As an example, the introduction part 50a defined by the weak seal part 52a of the component container 50 shown in FIG. 4 and the introduction part 50a including the stress concentration part 53 of the component container 50 shown in FIG. You may make it arrange | position inside the absorber 40. FIG.

  EXAMPLES Hereinafter, although this invention is demonstrated in detail using an Example, this invention is not limited to this Example.

  The component administration devices according to Examples 1 to 7 and the component administration devices according to Comparative Examples 1 to 4 were prepared as described below, and the prepared component administration devices were actually used and handled by ten panelists. Sex was evaluated.

<Ingredient administration device>
[Example 1]
As the component administration device according to Example 1, the component administration device described with reference to FIGS.

  First, an electrode device was produced as follows. A film made of polyethylene terephthalate having a thickness of 25 μm (“Lumirror (registered trademark)” manufactured by Toray Film Processing Co., Ltd.) was cut into a substantially rectangular shape (100 mm × 50 mm) and used as a support. Aluminum was physically vapor-deposited with a thickness of 400 mm on one surface of the polyethylene terephthalate film to form an aluminum vapor-deposited layer forming a metal layer. Next, the 1st electrode was formed by sticking zinc foil (thickness 5 micrometers) on an aluminum vapor deposition layer using a conductive double-sided adhesive ("T4420W" by Sony Chemical & Information Device Co., Ltd.). Moreover, the 2nd electrode was formed by sticking gold foil (thickness 1 micrometer) on an aluminum vapor deposition layer using a conductive double-sided adhesive ("T4420W" by Sony Chemical & Information Device Co., Ltd.). Insulating ink was applied to a region of the surface of the aluminum vapor deposition layer that was not covered with the first electrode and the second electrode by screen printing to form an insulator.

  A nonwoven fabric (“Benize (registered trademark)” manufactured by Asahi Kasei Fibers Co., Ltd.) was cut into a substantially rectangular shape (100 mm × 50 mm) and used as an absorbent.

  The laminated material (polyethylene terephthalate film having a thickness of 12 μm / adhesive / low-density polyethylene having a thickness of 50 μm) is folded so that the low-density polyethylene is inside, and further, the three sides are sealed to form a component container. A small rectangular bag (30 mm × 20 mm) was produced. The seal width was 2 mm at the broken bag portion and 5 mm at the other portions. 3 ml of essence was stored in a sachet forming an ingredient container.

  The absorber was positioned so as to extend between the first electrode and the second electrode of the electrode device, and the absorber was fixed to the electrode device using an adhesive means (double-sided adhesive tape). A component container was disposed between the absorber and the electrode device. The component container was fixed to the absorber using an adhesive means (double-sided adhesive tape). As shown in FIGS. 1 to 3, the component container was positioned between the electrode device and the absorber as a whole. In addition, the component administration device according to Example 1 manufactured in this way presses the component container through the electrode device and the absorber, whereby the component container is broken and the cosmetic liquid is absorbed into the absorber. And made it available for use.

[Example 2]
The component administration device according to Example 2 was different from the component administration device according to Example 1 only in that Nacorcorbyl phosphate was carried in an amount of 6 g / m ^{2 on} one side of the nonwoven fabric forming the absorber. . Loading of ascorbyl phosphate Na was carried out as follows. First, ascorbyl phosphate Na was sprayed on the nonwoven fabric, then ethanol was sprayed to wet the ascorbyl phosphate Na, and then dried and temporarily attached to the nonwoven fabric.

Example 3
As the component administration device according to Example 3, the component administration device described with reference to FIG. 4 was produced. The electrode device and the absorber of the component administration device according to Example 3 were configured the same as the electrode device and the absorber of the component administration device according to Example 1, respectively.

  As shown in FIG. 4, the component container is composed of a main part 50b and an introduction part 50a. The introduction part of the component container disposed between the electrode device and the absorber is defined by the weak seal part 52a, and the main part of the component container exposed from the electrode device and the absorber is formed by the strong seal part 52b. It was made to be defined. Specifically, two laminated materials (12 μm thick polyethylene terephthalate film / adhesive / 7 μm thick aluminum foil / adhesive / 50 μm thick lock & peel film (registered trademark, Mitsui DuPont)) A pouch that forms a component container was prepared by stacking the lock and peel film on the inside and further sealing the periphery. The weak seal part that is easy to break is formed by heating for 0.5 seconds at 120 ° and 0.2 Pa, and the strong seal part that is difficult to break is 0 at 190 ° and 0.2 Pa. Formed by heating for 5 seconds. The seal width was 2 mm. 3 ml of the lidocaine-containing preparation was contained in a sachet constituting the ingredient container.

  The absorber was positioned so as to extend between the first electrode and the second electrode of the electrode device, and the absorber was fixed to the electrode device using an adhesive means (double-sided adhesive tape). The introduction part of the component container was inserted between the absorber and the electrode device. As shown in FIG. 4, the adhesive means (double-sided adhesive tape) was positioned on both sides of the introduction part of the component container. On the other hand, the main part of the component container is exposed from the electrode device and the absorber so that the user can directly press it. The component administration device according to Example 3 manufactured in this way is configured so that the weak seal portion of the introduction portion forming the bag breaking portion of the component container is broken by pressing the main part of the component container. The component was released from the component container to the absorber. In addition, the component container that has released the components can be removed from the component administration device.

Example 4
As the component administration device according to Example 4, the component administration device described with reference to FIG. 5 was produced. The electrode device and the absorber of the component administration device according to Example 4 were configured the same as the electrode device and the absorber of the component administration device according to Example 1, respectively.

  The component container is made of two laminated materials (polyethylene terephthalate film with a thickness of 12 μm / adhesive / aluminum foil with a thickness of 7 μm / adhesive / low-density polyethylene with a thickness of 50 μm) so that the low-density polyethylene is on the inside. The sachets forming the component container were produced by stacking and sealing the periphery. The seal width was 2 mm at the broken bag portion and 5 mm at the other portions. 3 ml of the lidocaine-containing preparation was contained in a sachet constituting the ingredient container. As shown in FIG. 5, the component container has a stress concentrating portion composed of a sharp apex in a planar shape.

  Similar to the component administration apparatus described with reference to FIG. 5, the absorbent body is positioned so as to extend between the first electrode and the second electrode of the electrode device, and the first adhesive means 42 a having a relatively strong adhesive force. Was used to bond the absorber to the electrode device. A portion including the stress concentration portion of the component container was inserted between the absorber and the electrode device. Similarly to the component administration device described with reference to FIG. 5, the component container was bonded to the absorbent body using the second bonding means 42 b having a relatively weak adhesive force. The component administration device according to Example 4 manufactured as described above forms a bag breaking portion of the component container by pressing the component container, particularly by pressing an exposed portion of the component container. The stress concentration part was broken, and the component was released from the component container to the absorber. In addition, the component container that has released the components can be removed from the component administration device.

Example 5
As the component administration device according to Example 5, the component administration device described with reference to FIG. 6 was produced. Specifically, the component container of the component administration device according to Example 1 was disposed inside the absorber instead of being disposed between the absorber and the electrode device.

Example 6
The component administration device according to Example 6 is arranged inside the absorber instead of being arranged between the absorber and the electrode device, so that the introduction part of the component container of the component administration device according to Example 3 is arranged. Was made.

Example 7
The component administration device according to Example 7 is arranged by arranging the notch of the component container of the component administration device according to Example 4 inside the absorber instead of being arranged between the absorber and the electrode device. Was made.

[Comparative Example 1]
The component administration device according to Comparative Example 1 is different from the component administration device according to Example 1 in that the component container is provided separately from the component administration device. In the component administration device according to Comparative Example 1, the electrode device and the absorber were joined using an adhesive means (double-sided adhesive tape). In the component administration device according to Comparative Example 1, during use, the component container prepared separately from the absorber of the component administration device is first broken, and the components contained in the component container are hung on the absorber. It was made to absorb.

[Comparative Example 2]
The component administration device according to Comparative Example 2 was different from the component administration device according to Example 2 in that the component container was provided separately from the component administration device. In the component administration device according to Comparative Example 2, the electrode device and the absorber were joined using an adhesive means (double-sided adhesive tape). In the component administration device according to Comparative Example 2, during use, the component container prepared separately from the absorber of the component administration device is first broken, and the components contained in the component container are hung on the absorber. It was made to absorb.

[Comparative Example 3]
The component administration device according to Comparative Example 3 was different from the component administration device according to Example 3 in that the component container was provided separately from the component administration device. In the component administration device according to Comparative Example 3, the electrode device and the absorber were joined using an adhesive means (double-sided adhesive tape). In the component administration device according to Comparative Example 3, during use, the component container prepared separately from the absorber of the component administration device is first broken, and the components contained in the component container are hung on the absorber. It was made to absorb.

[Comparative Example 4]
The component administration device according to Comparative Example 4 is different from the component administration device according to Example 4 in that the component container is provided separately from the component administration device. In the component administration device according to Comparative Example 4, the electrode device and the absorber were joined using an adhesive means (double-sided adhesive tape). In the component administration device according to Comparative Example 4, during use, the component container prepared separately from the absorber of the component administration device is first broken, and the components contained in the component container are hung on the absorber. It was made to absorb.

<Evaluation method>
Ten panelists actually used the component administration devices according to Examples 1 to 4 and the component administration devices according to Comparative Examples 1 to 4, and evaluated the handling properties (usability). Regarding the handling property, it was investigated whether or not each panel felt complicated in handling until the component administration device was placed on the skin in a state where electricity can be applied.

<Evaluation results>
The results are shown in Table 1. In Table 1, in the “handleability” column, the number of panelists who felt troublesome in handling the component administration device was entered as a point. In Table 1, in the “determination” column, a circle is given to the component administration device whose score in the “handleability” column was 8 or more and 10 or less, and the score in the “handleability” column is Δ was assigned to a component administration device that was 4 or more and 7 or less, and × was assigned to a component administration device that had a point number of 3 or less in the “handleability” column. In the component administration devices according to Comparative Examples 1 to 4, it was necessary to carefully perform the operation of hanging the liquid component from the component container to the absorber, which was complicated. Furthermore, in the component administration device according to Comparative Examples 1 and 2, the component container must be broken with both hands, which makes handling more complicated.

DESCRIPTION OF SYMBOLS 10 Component administration apparatus 12 Circuit 14 Circuit 15 Electrode device 21 1st electrode 22 2nd electrode 25 Connection element 26 Metal layer 30 Insulator 35 Support body 40 Absorber 42 Adhesive means 42a 1st adhesive means 42b 2nd adhesive means 50 Component accommodation Body 50a Introduction part 50b Main part 51 Seal part 52a Weak seal part 52b Strong seal part 53 Stress concentration part 55 Bag breaking part, fracture part

Claims (6)

An electrode device having a first electrode and a second electrode that are spaced apart from each other and made of different materials, and a connection element for electrically connecting the first electrode and the second electrode;
An absorber disposed to face both the first electrode and the second electrode;
A component container containing a component that can be absorbed by the absorber,
The container is arranged such that at least a portion thereof is located between the electrode device and the absorber or at least a portion thereof is located inside the absorber;
A component administration device in which a self-electromotive closed circuit is formed by the absorber that has absorbed the component and the electrode device when in use. The container has a bag breaking portion that can be broken by pressurization,
The component administration device according to claim 1, wherein the container is disposed so that at least the bag breaking portion is located between the electrode device and the absorber or inside the absorber.   The component administration apparatus according to claim 1 or 2, wherein the component container is bonded to at least one of the absorber and the electrode device.   The said component container is a component administration apparatus as described in any one of Claims 1-3 which can be removed from between the said electrode device and the said absorber, or the inside of the said absorber.   An insulator that is located between the connection element and the absorber in a region between the first electrode and the second electrode and separates the connection element and the absorber from each other is provided, The component administration device according to any one of claims 1 to 4.   The said electric device further has the insulating support body provided in the opposite side to the said absorber side of the said 1st electrode, the said connection element, and the said 2nd electrode, The any one of Claims 1-5 The component administration device according to claim 1.

Images