JP2013539778A5 - - Google Patents
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- Publication number
- JP2013539778A5 JP2013539778A5 JP2013533265A JP2013533265A JP2013539778A5 JP 2013539778 A5 JP2013539778 A5 JP 2013539778A5 JP 2013533265 A JP2013533265 A JP 2013533265A JP 2013533265 A JP2013533265 A JP 2013533265A JP 2013539778 A5 JP2013539778 A5 JP 2013539778A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- composition according
- composition
- mol
- vgsc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 206010006187 Breast cancer Diseases 0.000 claims 3
- 208000026310 Breast neoplasm Diseases 0.000 claims 3
- 206010060862 Prostate cancer Diseases 0.000 claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 3
- 230000008883 metastatic behaviour Effects 0.000 claims 3
- 108010052164 Sodium Channels Proteins 0.000 claims 2
- 102000018674 Sodium Channels Human genes 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- XKLMZUWKNUAPSZ-UHFFFAOYSA-N N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide Chemical compound COC1=CC=CC=C1OCC(O)CN1CCN(CC(=O)NC=2C(=CC=CC=2C)C)CC1 XKLMZUWKNUAPSZ-UHFFFAOYSA-N 0.000 claims 1
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229960000213 ranolazine Drugs 0.000 claims 1
- 229960004181 riluzole Drugs 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
- 230000001052 transient effect Effects 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2010/001908 WO2012049440A1 (en) | 2010-10-13 | 2010-10-13 | Treatment of cancer/inhibition of metastasis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016019817A Division JP6465306B2 (ja) | 2016-02-04 | 2016-02-04 | 癌の治療／転移の阻害 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013539778A JP2013539778A (ja) | 2013-10-28 |
| JP2013539778A5 true JP2013539778A5 (enExample) | 2013-12-05 |
Family
ID=44022817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013533265A Pending JP2013539778A (ja) | 2010-10-13 | 2010-10-13 | 癌の治療／転移の阻害 |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US20130203764A1 (enExample) |
| EP (4) | EP2627321A1 (enExample) |
| JP (1) | JP2013539778A (enExample) |
| KR (1) | KR20140032346A (enExample) |
| CN (2) | CN103370060A (enExample) |
| AU (2) | AU2010362412A1 (enExample) |
| BR (1) | BR112013009086A2 (enExample) |
| CA (1) | CA2851694C (enExample) |
| DK (1) | DK3132791T3 (enExample) |
| IL (1) | IL225689A0 (enExample) |
| RU (1) | RU2013121744A (enExample) |
| SG (1) | SG189352A1 (enExample) |
| WO (1) | WO2012049440A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2013121744A (ru) | 2010-10-13 | 2014-11-20 | Мустафа Билгин Али ДЖАМГОЗ | Лечение рака/ингибирование метастазирования |
| WO2013123403A1 (en) * | 2012-02-15 | 2013-08-22 | Sanford-Burnham Medical Research Institute | Theranostics platform and methods of use |
| WO2017091574A1 (en) * | 2015-11-25 | 2017-06-01 | Health Research, Inc. | Riluzole and riluzole drug combinations for the treatment of prostate cancer |
| JP6465306B2 (ja) * | 2016-02-04 | 2019-02-06 | セレックス・オンコロジー・リミテッド | 癌の治療／転移の阻害 |
| IL292302B2 (en) * | 2016-05-20 | 2023-10-01 | Biohaven Pharm Holding Co Ltd | Use of glutamate modulating factors in cancer immunotherapy |
| CN110662545A (zh) * | 2017-02-10 | 2020-01-07 | 赛立斯肿瘤学创新有限公司 | 癌症治疗和转移抑制 |
| US20200123544A1 (en) * | 2018-10-22 | 2020-04-23 | Celex Oncology Innovations Limited | Gene therapy targeting the neonatal form of nav1.5 for treating cancer |
| WO2021078987A1 (en) | 2019-10-24 | 2021-04-29 | Celex Oncology Innovations Limited | Combination treatments for cancer |
| US12624101B2 (en) | 2020-01-21 | 2026-05-12 | Celex Oncology Innovations Limited | Monoclonal antibodies against neonatal Nav1.5 |
| US20230139204A1 (en) | 2020-03-09 | 2023-05-04 | Celex Oncology Innovations Limited | Measuring electric activity of cells for the evaluation of metastatic potential of cancer cells |
| WO2022005228A1 (ko) * | 2020-07-01 | 2022-01-06 | 국립암센터 | 3-케토아실 coa 타이올레이스 억제제 및 카르니틴 아실카르니틴 운반자 억제제를 포함하는 암 예방 또는 치료용 약학적 조성물 |
| WO2025078664A1 (en) | 2023-10-12 | 2025-04-17 | Celex Oncology Innovations Limited | Treatment of metastatic or invasive brain cancer |
| WO2025252860A1 (en) | 2024-06-04 | 2025-12-11 | Celex Oncology Innovations Limited | Ranolazine enantiomer for use in cancer treatment |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1659136A (zh) * | 2002-04-18 | 2005-08-24 | 弗吉尼亚大学专利基金会 | 新的钠通道阻滞剂 |
| CA2513399A1 (en) * | 2003-01-10 | 2004-07-29 | Threshold Pharmaceuticals, Inc. | Treatment of cancer with 2-deoxyglucose |
| US8835473B2 (en) * | 2004-04-16 | 2014-09-16 | Rutgers, The State University Of New Jersey | Methods and compositions for treating cancer |
| US9018222B2 (en) | 2006-03-27 | 2015-04-28 | Wex Medical Limited | Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy |
| US8394377B2 (en) * | 2008-02-21 | 2013-03-12 | The Regents Of The University Of Colorado | Methods for treating cancer using combination therapy |
| US20090247535A1 (en) * | 2008-03-26 | 2009-10-01 | Duke University | Use of ranolazine for non-cardiovascular disorders |
| US20110251144A1 (en) * | 2008-09-16 | 2011-10-13 | Massachusetts Institute Of Technology | Molecular modulators of the wnt/beta-catenin pathway |
| RU2013121744A (ru) | 2010-10-13 | 2014-11-20 | Мустафа Билгин Али ДЖАМГОЗ | Лечение рака/ингибирование метастазирования |
-
2010
- 2010-10-13 RU RU2013121744/15A patent/RU2013121744A/ru not_active Application Discontinuation
- 2010-10-13 CN CN2010800703488A patent/CN103370060A/zh active Pending
- 2010-10-13 EP EP10776791.5A patent/EP2627321A1/en not_active Withdrawn
- 2010-10-13 AU AU2010362412A patent/AU2010362412A1/en not_active Abandoned
- 2010-10-13 US US13/879,146 patent/US20130203764A1/en not_active Abandoned
- 2010-10-13 WO PCT/GB2010/001908 patent/WO2012049440A1/en not_active Ceased
- 2010-10-13 JP JP2013533265A patent/JP2013539778A/ja active Pending
- 2010-10-13 BR BR112013009086A patent/BR112013009086A2/pt not_active IP Right Cessation
- 2010-10-13 KR KR1020137012365A patent/KR20140032346A/ko not_active Withdrawn
- 2010-10-13 CN CN202110087549.9A patent/CN112755029A/zh active Pending
- 2010-10-13 SG SG2013026968A patent/SG189352A1/en unknown
- 2010-10-13 EP EP19211429.6A patent/EP3653206A1/en not_active Ceased
- 2010-10-13 EP EP16020321.2A patent/EP3132791B1/en active Active
- 2010-10-13 CA CA2851694A patent/CA2851694C/en active Active
- 2010-10-13 EP EP25174138.5A patent/EP4640281A3/en active Pending
- 2010-10-13 DK DK16020321.2T patent/DK3132791T3/da active
-
2013
- 2013-04-10 IL IL225689A patent/IL225689A0/en unknown
-
2015
- 2015-10-13 US US14/881,952 patent/US20160096812A1/en not_active Abandoned
-
2017
- 2017-04-06 AU AU2017202267A patent/AU2017202267B2/en active Active
-
2018
- 2018-06-07 US US16/002,555 patent/US20180346431A1/en not_active Abandoned
-
2019
- 2019-09-19 US US16/576,178 patent/US11634398B2/en active Active
-
2022
- 2022-12-19 US US18/068,263 patent/US12534444B2/en active Active
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