JP2013536864A - 第Ｘａ因子阻害剤の結晶形態 - Google Patents
第Ｘａ因子阻害剤の結晶形態 Download PDFInfo
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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| US201161454396P | 2011-03-18 | 2011-03-18 | |
| US61/454,396 | 2011-03-18 | ||
| PCT/US2011/050057 WO2012031017A1 (en) | 2010-09-01 | 2011-08-31 | CRYSTALLINE FORMS OF A FACTOR Xa INHIBITOR |
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| CN105085387A (zh) * | 2014-05-20 | 2015-11-25 | 四川海思科制药有限公司 | 贝曲西班盐及其制备方法和用途 |
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| CN106995405A (zh) * | 2016-01-25 | 2017-08-01 | 重庆医药工业研究院有限责任公司 | 一种贝曲西班马来酸盐无定型物及其制备方法 |
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| EP3510996A1 (en) * | 2018-01-11 | 2019-07-17 | Sandoz AG | Pharmaceutical compositions of betrixaban |
| CN108570003A (zh) * | 2018-06-01 | 2018-09-25 | 浙江宏元药业股份有限公司 | 一种贝曲西班马来酸盐的一水无定形及其制备方法 |
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| JP2019135258A (ja) | 2019-08-15 |
| JP2015232046A (ja) | 2015-12-24 |
| AU2011295909B2 (en) | 2015-05-21 |
| JP2018024709A (ja) | 2018-02-15 |
| AR082804A1 (es) | 2013-01-09 |
| US8946269B2 (en) | 2015-02-03 |
| PT2611779T (pt) | 2016-11-21 |
| US20120071519A1 (en) | 2012-03-22 |
| IL224698A (en) | 2017-01-31 |
| EP2611779B1 (en) | 2016-08-10 |
| WO2012031017A1 (en) | 2012-03-08 |
| NZ608442A (en) | 2015-04-24 |
| TW201221128A (en) | 2012-06-01 |
| CA2810004C (en) | 2019-09-10 |
| CN103261161A (zh) | 2013-08-21 |
| EP2611779A1 (en) | 2013-07-10 |
| AU2011295909A1 (en) | 2013-04-04 |
| ES2603084T3 (es) | 2017-02-23 |
| CA2810004A1 (en) | 2012-03-08 |
| CN103261161B (zh) | 2016-04-27 |
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