JP2013514799A5 - - Google Patents
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- Publication number
- JP2013514799A5 JP2013514799A5 JP2012545428A JP2012545428A JP2013514799A5 JP 2013514799 A5 JP2013514799 A5 JP 2013514799A5 JP 2012545428 A JP2012545428 A JP 2012545428A JP 2012545428 A JP2012545428 A JP 2012545428A JP 2013514799 A5 JP2013514799 A5 JP 2013514799A5
- Authority
- JP
- Japan
- Prior art keywords
- rrna
- mutation
- quadruplet codon
- translating
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004465 16S Ribosomal RNA Proteins 0.000 claims 7
- 230000035772 mutation Effects 0.000 claims 3
- 108020004705 Codon Proteins 0.000 claims 2
- 108020004999 Messenger RNA Proteins 0.000 claims 1
- 229920002106 messenger RNA Polymers 0.000 claims 1
Claims (7)
- Ａ１１９６に変異を含む１６Ｓ ｒＲＮＡ。
- 変異がＡ１１９６Ｇである、請求項１に記載の１６Ｓ ｒＲＮＡ。
- Ｃ１１９５及び／又はＡ１１９７に変異をさらに含む、請求項１又は２に記載の１６Ｓ ｒＲＮＡ。
- （ｉ）Ｃ１１９５Ａ及びＡ１１９６Ｇ；又は
（ii）Ｃ１１９５Ｔ、Ａ１１９６Ｇ、及びＡ１１９７Ｇ；又は
（iii）Ａ１１９６Ｇ及びＡ１１９７Ｇ
を含む、請求項１〜３のいずれかに記載の１６Ｓ ｒＲＮＡ。 - Ａ５３１Ｇ及びＵ５３４Ａをさらに含む、請求項１〜４のいずれかに記載の１６Ｓ ｒＲＮＡ。
- クアドラプレットコドンを翻訳することができ、請求項１〜５のいずれかに記載の１６Ｓ ｒＲＮＡを含むリボソーム。
- 少なくとも１つのクアドラプレットコドンを含むｍＲＮＡの翻訳における、請求項１〜６のいずれかに記載の１６Ｓ ｒＲＮＡの使用。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28842109P | 2009-12-21 | 2009-12-21 | |
| GB0922351.2 | 2009-12-21 | ||
| US61/288421 | 2009-12-21 | ||
| GBGB0922351.2A GB0922351D0 (en) | 2009-12-21 | 2009-12-21 | Orthogonal Q-Ribosomes |
| PCT/GB2010/002296 WO2011077075A1 (en) | 2009-12-21 | 2010-12-20 | Orthogonal q-ribosomes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013514799A JP2013514799A (ja) | 2013-05-02 |
| JP2013514799A5 true JP2013514799A5 (ja) | 2014-01-16 |
Family
ID=41717344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545428A Pending JP2013514799A (ja) | 2009-12-21 | 2010-12-20 | 直交性ｑ−リボソーム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120264926A1 (ja) |
| EP (1) | EP2516644A1 (ja) |
| JP (1) | JP2013514799A (ja) |
| CN (1) | CN102782132A (ja) |
| AU (1) | AU2010334671A1 (ja) |
| CA (1) | CA2785266A1 (ja) |
| GB (1) | GB0922351D0 (ja) |
| WO (1) | WO2011077075A1 (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202110137D0 (en) | 2021-07-14 | 2021-08-25 | Res & Innovation Uk | Methods for optimising protein production |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0623974D0 (en) | 2006-11-30 | 2007-01-10 | Medical Res Council | Evolved orthogonal ribosomes |
-
2009
- 2009-12-21 GB GBGB0922351.2A patent/GB0922351D0/en not_active Ceased
-
2010
- 2010-12-20 US US13/517,372 patent/US20120264926A1/en not_active Abandoned
- 2010-12-20 JP JP2012545428A patent/JP2013514799A/ja active Pending
- 2010-12-20 CN CN201080064303XA patent/CN102782132A/zh active Pending
- 2010-12-20 CA CA2785266A patent/CA2785266A1/en not_active Abandoned
- 2010-12-20 AU AU2010334671A patent/AU2010334671A1/en not_active Abandoned
- 2010-12-20 EP EP10810865A patent/EP2516644A1/en not_active Withdrawn
- 2010-12-20 WO PCT/GB2010/002296 patent/WO2011077075A1/en active Application Filing