JP2013214183A - Analysis result reliability determination device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a system enabling even a beginner or consuming public to easily know reliability of analytical data.SOLUTION: An analysis result reliability determination device being a device coupled to an analyzer through data communication network includes: a component reliability data holding part for holding reliability data of various components capable of composing the analyzer; a component information acquisition part for acquiring information specifying a component composing the analyzer, from the analyzer; a reliability determination part for determining a reliability quality of the analyzer according to the information specifying a component; a determination result transmission part for transmitting determined quality information to the analyzer.

Description

  The present invention relates to an analysis result reliability determination apparatus that determines the reliability of analysis data.

  For example, when an analysis is performed using an analyzer such as a liquid chromatograph or a gas chromatograph, data acquired as a result of the analysis (referred to as “analysis data”) is processed or processed in the analyzer itself. Instead, it is often processed or analyzed in an analysis data processing apparatus connected to the analysis apparatus directly or via a network (Patent Document 1).

  The entity of the analysis data processing apparatus is usually a general-purpose computer in which predetermined analysis data processing software is installed.

  In such an analysis system, together with the analysis data, information on the analysis apparatus used for the analysis and information on the analysis conditions are collected in the analysis data processing apparatus and stored in association with each other. These pieces of information are used not only as information for reproducing the same analysis but also for evaluating the reliability of the analysis data.

  For example, when the air condition is inspected and the water quality of the river is inspected, the analysis result is of great concern to local residents. Also, these inspections are often based on legal regulations. In such cases, since the reliability of the analysis data is as important information as the analysis result, it is often required to be provided to the user of the analysis data together with the analysis result.

JP 2006-119071 A

  Analytical instrument manufacturers increase the accuracy and reliability of each instrument in order to guarantee the reliability of analysis data, and ensure that the entire analysis system has a predetermined reliability. However, on the side where the analysis system is used, there are cases where a part of the equipment (components) constituting the analysis system is exchanged for a different one from the same manufacturer or a different manufacturer. For example, in the high-performance liquid chromatograph system of Company A, if the detector and autosampler are the products of Company A, and the pump and oven are replaced with products of Company B, Company B will compare with Company A products. If the reliability of the product is generally low, the reliability of the entire high performance liquid chromatograph apparatus may be lower than the reliability initially guaranteed by the company A system.

  In addition, the analysis procedure may affect the analysis result, but if the predetermined procedure or condition is not observed, the reliability of the analysis data may be reduced.

  The reliability of these devices and the reliability of the analysis conditions are usually judged by whether or not a predetermined standard is satisfied. If the standard is satisfied, the approval is given. The information is provided to the user in such a way that is not given.

  Furthermore, not only the reliability of the apparatus and analysis conditions, but also whether or not they consider environmental loads may be certified. For example, whether or not a recyclable material is used in the apparatus, or whether or not an environment-friendly solution is used as a solvent for the analysis sample is also regarded as important when the analysis result is used. These can also be called “reliability” of analysis data in a broad sense.

  An expert can know how much reliability the analysis data has from the information on the analysis apparatus and the analysis conditions stored in association with the analysis data. However, it is difficult for beginners, general consumers, and the like to know the reliability of analysis data from these information.

  The present invention has been made in view of the above-mentioned problems, and the purpose of the present invention is to enable even beginners and general consumers to easily know the reliability (in a broad sense) of analysis data. Is to provide a secure system.

In order to solve the above problems, the first aspect of the present invention is an apparatus connected to an analyzer via a data communication network,
A component reliability data holding unit that holds reliability data of various components that can constitute the analyzer;
A component information acquisition unit for acquiring component specifying information for specifying components constituting the analyzing device from the analyzing device;
A reliability determination unit that determines whether the analysis apparatus is reliable based on the component identification information;
An analysis result reliability determination apparatus comprising: a determination result transmission unit configured to transmit the determined pass / fail information to the analysis apparatus.

  The analysis apparatus may be a single analysis apparatus or may include an analysis data processing apparatus that receives analysis data generated by the analysis apparatus and performs various data processing on the analysis data.

  The information specifying the component of the analyzer may be sent from the analyzer, and the analysis result reliability determination device (component information acquisition unit) actively inquires of the analyzer and from the analyzer It may be acquired. Further, the information for specifying the component may be information for specifying the model of the component, or information for specifying an individual such as a manufacturing number. Accordingly, the component reliability data held by the component reliability data holding unit is assumed to be reliability for each model or reliability for each individual.

Moreover, the thing of the 2nd aspect of this invention is an apparatus connected to the analyzer via the data communication network,
An analysis condition reliability data holding unit that holds reliability data of various analysis conditions that can be used in the analysis performed by the analyzer;
From the analyzer, an analysis condition information acquisition unit that acquires analysis condition information used for analysis performed by the analyzer or used for analysis performed by the analyzer;
A reliability determination unit that determines whether or not the reliability of the analysis performed or performed in the analysis device is based on the analysis condition information sent from the analysis device;
An analysis result reliability determination apparatus comprising: a determination result transmission unit configured to transmit the determined pass / fail information to the analysis apparatus.

  Similar to the first aspect, the analysis device may be a single analysis device or may include an analysis data processing device that receives analysis data generated by the analysis device and performs various data processing on the analysis data. The analysis condition information may be sent from the analysis device, or the analysis result reliability determination device (analysis condition information acquisition unit) may actively query the analysis device and acquire it from the analysis device. .

  The analysis condition information is information for reproducing the same analysis such as an analysis procedure and a sample used for the analysis. Further, the analysis condition reliability data held by the analysis condition reliability data holding unit is reliability of various analysis procedures and analysis samples, and environmental load reduction.

  The analysis result reliability determination apparatus according to the present invention determines the reliability of the analysis apparatus and the reliability of the analysis performed by the analysis apparatus, and sends the result to the analysis apparatus. In the analyzer, if the quality information determined is stored in association with the analysis data and the quality information is displayed together with the analysis data as required, anyone can easily know the reliability of the analysis data. It becomes possible.

The schematic block diagram which shows 1st Example of the analysis result reliability determination apparatus which concerns on this invention. Component identification information (a) sent to the analysis result reliability determination apparatus of the first embodiment, and reliability corresponding to the component identification information acquired from the component reliability data holding unit of the analysis result reliability determination apparatus The figure which shows an example of data (b). The figure which shows an example of the analysis report produced with the analysis data processing apparatus based on the determination result from the analysis result reliability determination apparatus of 1st Example. Component identification information (a) sent to the analysis result reliability determination apparatus of the first embodiment, and reliability corresponding to the component identification information acquired from the component reliability data holding unit of the analysis result reliability determination apparatus The figure which shows another example of data (b). The figure which shows another example of the analysis report produced with the analysis data processing apparatus based on the determination result from the analysis result reliability determination apparatus of 1st Example. The schematic block diagram which shows 2nd Example of the analysis result reliability determination apparatus which concerns on this invention. The figure which shows an example of the analysis pattern preserve | saved at the analysis condition reliability data holding | maintenance part of the analysis result reliability determination apparatus of 2nd Example. The figure which shows an example of the analysis report with respect to the analysis performed using the analysis pattern recognized beforehand. The schematic block diagram which shows 3rd Example of the analysis result reliability determination apparatus which concerns on this invention. The figure which shows an example which determines the reliability of an analysis result by the combination of component specific information and analysis condition information in the analysis result reliability determination apparatus of 3rd Example.

  Hereinafter, an example of an embodiment of an analysis result reliability determination apparatus according to the present invention will be described in detail with reference to the drawings.

  FIG. 1 is a schematic configuration diagram showing a first embodiment of an analysis result reliability determination apparatus according to the present invention. An analysis result reliability determination device (hereinafter abbreviated as “determination device”) 4 according to the present embodiment is connected to the analysis system 1 via a data communication network NW such as the Internet or an intranet so as to be able to communicate with each other. The analysis system 1 includes a liquid high-speed chromatograph (hereinafter referred to as “analyzer”) 2 and an analysis data processor 3 connected to the analyzer 2. The analyzer 2 includes a plurality of devices (components) such as a detector, an autosampler, a pump, and an oven.

  In the example of FIG. 1, one analysis device 2 is directly connected to one analysis data processing device 3, but for example, a plurality of different types or the same type of analysis devices The analysis data processing apparatus 3 may be connected to each other via a local area network or the like.

  The analysis data processing device 3 and the determination device 4 have a CPU (Central Processing Unit) which is a central processing unit, a monitor (display unit) including a memory, an LCD (Liquid Crystal Display), an input including a keyboard and a mouse. A general-purpose computer connected to a storage unit composed of a large-capacity storage device such as a hard disk or an SSD (Solid State Drive).

The analysis data processing device 3 includes a component information transmission unit 5 and a determination result processing unit 6 as a configuration embodied in software, in addition to a function of processing analysis data acquired as a result of analysis.
Further, the determination device 4 includes a component reliability data holding unit 7 configured by a database, a component information acquisition unit 8, a reliability determination unit 9, and a determination result transmission unit 10 embodied in software. .

The component information transmission unit 5 of the analysis data processing device 3 collects component identification information of each component constituting the analysis device 2 and transmits it to the determination device 4 (component information acquisition unit 8) at a predetermined timing. The component identification information may not be collected every time it is analyzed, but may be acquired in advance. Further, the component information transmission unit 5 may be provided not on the analysis data processing device 3 but on the analysis device 2.
The determination result processing unit 6 will be described later.

  The component reliability data holding unit 7 of the determination device 4 stores reliability data of various components that can constitute the analysis device 2. The reliability data stored in the component reliability data holding unit 7 is information for determining the reliability of each component in the reliability determination unit 9. For example, the manufacturer's name, the manufacturing country, the manufacturing factory name, and the manufacturing time It can include evaluation of analytical instruments that have been verified by third parties such as research institutions and public institutions.

The component information acquisition unit 8 of the determination device 4 acquires the component identification information sent from the component information transmission unit 5 and sends it to the reliability determination unit 9. Based on the component identification information sent from the component information acquisition unit 8, the reliability determination unit 9 acquires the reliability data corresponding to the component identification information from the component reliability data holding unit 7. And reliability determination is performed in light of a predetermined reference given in advance.
Here, the “predetermined standard” refers to, for example, the same manufacturer or country of manufacture of all the components constituting the analysis device 2, evaluation of each component verified by a third-party organization being a certain level or more, etc. It is. The “predetermined criterion” may be one or plural. For example, when there are a plurality of “predetermined criteria”, it can be determined that the reliability is high if all the criteria are satisfied, and the reliability is low if there are those that do not satisfy the criteria.

  The result of the reliability determination in the reliability determination unit 9 of the determination device 4 is transmitted to the determination result processing unit 6 of the analysis data processing device 3 by the determination result transmission unit 10. The determination result processing unit 6 of the analysis data processing device 3 includes the reliability determination result transmitted from the determination result transmission unit 10 of the determination device 4 in the analysis data. That is, when the reliability determination result is stored together with the analysis data or the analysis report is created, the reliability determination result is displayed in the analysis report.

  FIG. 2 shows an example of component identification information (a) sent to the determination apparatus 4 and reliability data (b) corresponding to the component identification information acquired from the component reliability data holding unit 7. In the example of FIG. 2, a serial number is used as component specifying information. The component reliability data holding unit 7 stores information on the country of manufacture, manufacturer, and quality as reliability data corresponding to these pieces of information. The reliability determination unit 9 performs reliability determination based on predetermined reliability based on these reliability data. In this embodiment, when all three of “all manufacturing countries are the same”, “all manufacturers are the same”, and “all high quality” are satisfied, it is determined that the reliability of the analyzer 2 is high. As shown in FIG. 2 (b), since the four components constituting the analyzer 2 satisfy all three criteria, the reliability determination unit 9 determines that the reliability is high and determines the result. The result is transmitted from the result transmitting unit 10 to the determination result processing unit 6 of the analysis data processing device 3. As a result of the reliability determination, the determination result processing unit 6 displays a certification mark “highly reliable system” in the analysis report as shown in FIG. Thus, by displaying the result of reliability determination sent from the determination device 4 together with the analysis report, anyone can easily know the reliability of the analysis report.

  When the reliability determination result is low, the reliability determination unit 9 of the determination device 4 may include information (attention information) that calls attention to the component configuration in the reliability determination result. In addition to this, the determination result processing unit 6 of the analysis data processing device 3 displays attention information on the analysis report to be created or the display unit of the analysis data processing device 3. For example, as shown in the example of FIG. 4, when some components do not meet the criteria of the reliability determination unit 9, the reliability determination unit 9 determines that the reliability of the analysis device 2 is low. If the evaluation information is included in the evaluation and the warning information is displayed on the display section of the analysis report or the analysis apparatus 2 as shown in FIG. Can be improved.

  Note that the determination device 4 is desirably provided in an organization (for example, a research institution or a public institution) different from the organization having the analysis system 1 in order to ensure objectivity by a third party and reliability of the determination result. .

  FIG. 6 is a schematic configuration diagram showing a second embodiment of the analysis result reliability determination apparatus according to the present invention. The analysis result reliability determination device (hereinafter referred to as “determination device”) 14 according to the present embodiment uses the analysis system 11 and the data communication network NW such as the Internet or an intranet in the same manner as the determination device 4 according to the first embodiment. Are connected so that they can communicate with each other. The analysis system 11 includes an analysis device 12 and an analysis data processing device 13 connected to the analysis device 12.

The analysis data processing device 13 includes an analysis condition information transmission unit 15 and a determination result processing unit 16 that are embodied as software. The analysis condition information transmission unit 15 may be provided not on the analysis data processing device 13 but on the analysis device 12.
The determination device 14 includes an analysis condition reliability data holding unit 17 configured by a database, an analysis condition information acquisition unit 18 embodied as software, a reliability determination unit 19, and a determination result transmission unit 20. ing. The analysis condition reliability data holding unit 17 stores reliability data for various analysis conditions that can be used in the analysis performed by the analyzer 12.

  The analysis condition information transmission unit 15 of the analysis data processing device 13 uses the analysis condition information (for example, method file) used for the analysis performed by the analysis device 12 or used for the analysis performed by the analysis device 12. It transmits to the determination apparatus 14 (analysis condition information acquisition part 18) at a predetermined timing.

The analysis condition information acquisition unit 18 of the determination device 14 acquires the analysis condition information sent from the analysis condition information transmission unit 15 and sends it to the reliability determination unit 19. Based on the analysis condition information sent from the analysis condition information acquisition unit 18, the reliability determination unit 19 receives from the analysis condition reliability data holding unit 17 the reliability of the analysis procedure and solvent used corresponding to the analysis condition information. Get the data. And reliability determination is performed in light of a predetermined reference given in advance.
Here, the “predetermined standard” means that no solvent harmful to the environment is used, the amount of the solvent harmful to the environment is small, an analysis method verified by a third party organization, etc. is adopted. .

  The result of the reliability determination in the reliability determination unit 19 of the determination device 14 is transmitted to the determination result processing unit 16 of the analysis data processing device 13 by the determination result transmission unit 20. The determination result processing unit 16 of the analysis data processing device 13 includes the reliability determination result transmitted from the determination result transmission unit 20 of the determination device 14 in the analysis data. That is, when the reliability determination result is stored together with the analysis data or the analysis report is created, the reliability determination result is displayed in the analysis report.

The analysis pattern reliability data holding unit 17 of the determination device 14 stores a pre-recognized analysis pattern, and the analyst selects a predetermined analysis pattern from the analysis condition reliability data holding unit 17 as necessary. You can also get a method file.
For example, in the example of FIG. 7, method files of three analysis patterns of “low flow rate”, “hazardous solvent not used”, and “S company recommended eco” are stored in the analysis condition reliability data holding unit 17. From among these, for example, if an analyst obtains a method file of “no-xxx.lcm” and analyzes it using the analysis device 12, the determination device 14 determines the analysis result from the method file name. The reliability determination unit 19 performs the determination that “hazardous solvent is not used”. In response to this result, the determination result processing unit 16 displays the result of the reliability determination of “hazardous solvent not used” indicating that the solvent harmful to the environment is not used in the analysis report (FIG. 8). .

  The determination device 4 of the first embodiment and the determination device 14 of the second embodiment can be combined into one device. FIG. 9 is a schematic configuration diagram showing a third embodiment of the analysis result reliability determination apparatus according to the present invention. The analysis result reliability determination device (hereinafter referred to as “determination device”) 24 of this embodiment is connected to the analysis system 21 via a data communication network NW such as the Internet or an intranet so as to be able to communicate with each other. The analysis system 21 includes an analysis device 22 and an analysis data processing device 23 connected to the analysis device 22.

  The analysis data processing device 23 includes an information transmission unit 25 and a determination result processing unit 26 that are embodied as software. Further, the determination device 24 includes a reliability data holding unit 27 configured by a database, an information acquisition unit 28 embodied as software, a reliability determination unit 29, and a determination result transmission unit 30.

  The information transmission unit 25 of the analysis data processing device 23 transmits the component specifying information and the analysis condition information to the determination device 24 (information acquisition unit 28) at a predetermined timing.

  The reliability data holding unit 27 of the determination device 24 stores reliability data for various components and various analysis conditions. The information acquisition unit 28 of the determination device 24 acquires component specifying information and analysis condition information sent from the information transmission unit 15 and sends them to the reliability determination unit 29. The reliability determination unit 29 acquires corresponding reliability data from the reliability data holding unit 27 based on the component identification information and analysis condition information sent from the information acquisition unit 28. And reliability determination is performed in light of a predetermined reference given in advance.

In the determination device 24 of the present embodiment, the analysis condition information corresponding to the device characteristics for each component can be verified by verifying both the component identification information and the analysis condition information. For example, if various parameters included in the analysis condition information (such as oven temperature and pump flow rate) exceed the appropriate range for each component specified from the component specification information, the data obtained as a result of the analysis Of course, the reliability is low. In that case, the reliability determination unit 29 determines that the reliability of the analysis data is low (FIG. 10). If necessary, the reliability determination unit 29 sends to the analysis device 2 recommendation information that the configuration of components and / or analysis conditions should be changed.
Referring to the example of FIG. 10, the component specifying information is not changed, that is, the configuration of the component is not changed, and the recommended information for setting the oven set temperature to 80 ° C. or less in the analysis condition is sent and / or analyzed Assuming that the condition information remains unchanged, that is, the analysis conditions are not changed, the component specifying information is sent with recommendation information to use an oven that can handle a set temperature of 85 ° C. Also, both can be changed, and a combination of a component and an analysis condition that can obtain high reliability may be sent as recommended information. When changing analysis conditions and components, the recommended components and analysis conditions can be selected in consideration of combinations with other components and analysis conditions (for example, the manufacturer and the country of manufacture are the same). desirable.

  As described above, even if multiple analyzers are installed in the analysis system and various types of components are mixed in each analyzer, the analysis conditions of each analyzer can be changed appropriately according to the components, and analysis can be performed. Components can be configured according to conditions, and it is possible to perform analysis with assured reliability.

The result of the reliability determination in the reliability determination unit 29 of the determination device 24 is transmitted to the determination result processing unit 26 of the analysis data processing device 23 by the determination result transmission unit 30. The determination result processing unit 26 of the analysis data processing device 23 analyzes the reliability determination result transmitted from the determination result transmission unit 30 of the determination device 24 (with recommendation information if recommended information is included) as analysis data. Include in
The reliability determination result created by the reliability determination unit 29 may be made independent of the reliability based on the above-described apparatus configuration and the reliability based on the analysis condition information, or just based on the determination results of both. One reliability determination result may be created.

  The analysis result reliability determination apparatus according to the present invention is not limited to the above-described embodiment, and can be appropriately modified.

DESCRIPTION OF SYMBOLS 1, 11, 21 ... Analysis system 2, 12, 22 ... Analysis apparatus 3, 13, 23 ... Analysis data processing apparatus 4, 14, 24 ... Analysis result reliability determination apparatus 5 ... Component information transmission part 6, 16, 26 ... Determination result processing unit 7... Component reliability data holding unit 8... Component information acquisition unit 9, 19, 29 .. reliability determination unit 10, 20, 30 .. determination result transmission unit 15. Property data holding unit 18 ... analysis condition information obtaining unit 25 ... information transmitting unit 27 ... reliability data holding unit 28 ... information obtaining unit NW ... data communication network

Claims (3)

A device connected to the analyzer via a data communication network,
A component reliability data holding unit that holds reliability data of various components that can constitute the analyzer;
A component information acquisition unit for acquiring component specifying information for specifying components constituting the analyzing device from the analyzing device;
A reliability determination unit that determines whether the analysis apparatus is reliable based on the component identification information;
An analysis result reliability determination apparatus comprising: a determination result transmission unit configured to transmit the determined pass / fail information to the analysis apparatus. A device connected to the analyzer via a data communication network,
An analysis condition reliability data holding unit that holds reliability data of various analysis conditions that can be used in the analysis performed by the analyzer;
From the analyzer, an analysis condition information acquisition unit that acquires analysis condition information used for analysis performed by the analyzer or used for analysis performed by the analyzer;
A reliability determination unit that determines whether or not the reliability of the analysis performed or performed in the analysis device is based on the analysis condition information sent from the analysis device;
An analysis result reliability determination apparatus comprising: a determination result transmission unit configured to transmit the determined pass / fail information to the analysis apparatus.   The analysis result reliability determination device according to claim 1, wherein the analysis device displays the pass / fail information together with analysis data acquired as a result of analysis performed by the analysis device.

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