JP2013064722A5 - - Google Patents
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- JP2013064722A5 JP2013064722A5 JP2012109702A JP2012109702A JP2013064722A5 JP 2013064722 A5 JP2013064722 A5 JP 2013064722A5 JP 2012109702 A JP2012109702 A JP 2012109702A JP 2012109702 A JP2012109702 A JP 2012109702A JP 2013064722 A5 JP2013064722 A5 JP 2013064722A5
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- groove
- labeling
- pit
- bead
- blu
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図10の構成の例としては、例えば標識用ビーズ110の直径が140nmであり、反射光の位相が約1/2波長の標識用ビーズ110をグルーブ107またはビット109に固定化し、ブルーレイディスクの読み取りと同等の光学定数を有する読み取り装置1で再生する。この場合のトラックピッチは、ブルーレイディスクと同等の320nmとし、グルーブ107またはピット109の深さは20nmとする。これにより、グルーブ107またはピット109の形状は読み取り装置1側からみて凹形状となり、標識用ビーズ110の直径がグルーブ107またはピット109の深さより大きいことから、標識用ビーズ110はトラック領域105の表面から突出した形で固定化されている。 As an example of the configuration of FIG. 10, for example, the labeling bead 110 having a diameter of 140 nm and a reflected light phase of about ½ wavelength is fixed to the groove 107 or the bit 109 to read a Blu-ray disc. Is reproduced by the reading device 1 having an optical constant equivalent to the above. In this case, the track pitch is 320 nm, which is the same as that of a Blu-ray disc, and the depth of the groove 107 or pit 109 is 20 nm. Thereby, the shape of the groove 107 or the pit 109 becomes a concave shape when viewed from the reading device 1 side, and the diameter of the labeling bead 110 is larger than the depth of the groove 107 or the pit 109. It is fixed in a protruding form.
このような、標識用ビーズ110の反射率と信号出力の変化率を解析した結果を図11に示す。図11の結果は、標識用ビーズ110の反射率による信号出力の変化率の依存性をスカラ解析理論に基づき計算した結果である。また、実験においてもほぼ同じ傾向の特性が得られることを確認している。 FIG. 11 shows the result of analyzing the reflectance of the labeling beads 110 and the change rate of the signal output. The result of FIG. 11 is the result of calculating the dependence of the change rate of the signal output due to the reflectance of the labeling beads 110 based on the scalar analysis theory. In experiments, it was confirmed that characteristics with almost the same tendency were obtained .
図12の構成の例としては、例えば直径が140nmの標識用ビーズ110をグルーブ107またはピット109に固定化し、ブルーレイディスクの読み取りと同等の光学定数を有する読み取り装置1で再生する。この場合のトラックピッチは、ブルーレイディスクと同等の320nmとし、グルーブ107またはピット109の深さは20nmとする。これにより、グルーブ107またはピット109の形状は読み取り装置1側からみて凹形状となり、標識用ビーズ110の直径がグルーブ107またはピット109の深さより大きいことから、標識用ビーズ110はトラック領域105の表面から突出した形で固定化されている。 As an example of the configuration in FIG. 12, for example, a labeling bead 110 having a diameter of 140 nm is fixed to the groove 107 or the pit 109 and is reproduced by the reading device 1 having an optical constant equivalent to that of reading a Blu-ray disc. In this case, the track pitch is 320 nm, which is the same as that of a Blu-ray disc, and the depth of the groove 107 or pit 109 is 20 nm. Thereby, the shape of the groove 107 or the pit 109 becomes a concave shape when viewed from the reading device 1 side, and the diameter of the labeling bead 110 is larger than the depth of the groove 107 or the pit 109. It is fixed in a protruding form.
また、図12に上述した構成において標識用ビーズ110を読み取った場合の信号を模式的に示す。図10に示すように、標識用ビーズ110がグルーブ107またはランド109内に存在することで反射率が上昇し、信号出力レベルを上昇させる(波形(a)、(b)、(d)、(e))。ここで標識用ビーズ110の反射率が高い場合は、信号出力の変化率を大きくすることができる(波形(b)、(e))。
FIG. 12 schematically shows a signal when the labeling bead 110 is read in the configuration described above. As shown in FIG. 10, the presence of the labeling beads 110 in the groove 107 or the land 109 increases the reflectivity and increases the signal output level (waveforms (a), (b), (d), ( e)). Here, when the reflectance of the bead 110 for labeling is high, the rate of change in signal output can be increased (waveforms (b) and (e)) .
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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JP2012109702A JP5958066B2 (en) | 2011-05-13 | 2012-05-11 | Sample analysis disc |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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JP2011108257 | 2011-05-13 | ||
JP2011108257 | 2011-05-13 | ||
JP2011188549 | 2011-08-31 | ||
JP2011188549 | 2011-08-31 | ||
JP2012109702A JP5958066B2 (en) | 2011-05-13 | 2012-05-11 | Sample analysis disc |
Publications (3)
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JP2013064722A JP2013064722A (en) | 2013-04-11 |
JP2013064722A5 true JP2013064722A5 (en) | 2014-06-05 |
JP5958066B2 JP5958066B2 (en) | 2016-07-27 |
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JP2012109702A Active JP5958066B2 (en) | 2011-05-13 | 2012-05-11 | Sample analysis disc |
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JP (1) | JP5958066B2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6225798B2 (en) * | 2014-03-31 | 2017-11-08 | 株式会社Jvcケンウッド | Analysis apparatus and analysis method |
JP6237417B2 (en) * | 2014-03-31 | 2017-11-29 | 株式会社Jvcケンウッド | Analysis apparatus and analysis method |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH01292631A (en) * | 1988-05-18 | 1989-11-24 | Nakamichi Corp | Tracking controlling method |
US5922617A (en) * | 1997-11-12 | 1999-07-13 | Functional Genetics, Inc. | Rapid screening assay methods and devices |
US6760298B2 (en) * | 2000-12-08 | 2004-07-06 | Nagaoka & Co., Ltd. | Multiple data layer optical discs for detecting analytes |
US20100255603A9 (en) * | 2002-09-12 | 2010-10-07 | Putnam Martin A | Method and apparatus for aligning microbeads in order to interrogate the same |
JP2007501407A (en) * | 2003-03-03 | 2007-01-25 | 長岡実業株式会社 | Methods and apparatus used for the detection and quantification of various cell types and the use of optical biodiscs to do this |
JP2006349594A (en) * | 2005-06-20 | 2006-12-28 | Matsushita Electric Ind Co Ltd | Disc for sample analysis and sample analysis apparatus |
CA2691093A1 (en) * | 2007-06-12 | 2008-12-18 | Lingvitae Holding As | Optical discs for analysing biomolecules |
US8277628B2 (en) * | 2007-07-13 | 2012-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus using electric field for improved biological assays |
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2012
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