JP2012515898A5 - - Google Patents
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- JP2012515898A5 JP2012515898A5 JP2011546447A JP2011546447A JP2012515898A5 JP 2012515898 A5 JP2012515898 A5 JP 2012515898A5 JP 2011546447 A JP2011546447 A JP 2011546447A JP 2011546447 A JP2011546447 A JP 2011546447A JP 2012515898 A5 JP2012515898 A5 JP 2012515898A5
- Authority
- JP
- Japan
- Prior art keywords
- stress
- quality
- red blood
- value
- presentation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000003743 erythrocyte Anatomy 0.000 claims description 15
- 102000001554 Hemoglobins Human genes 0.000 claims description 12
- 108010054147 Hemoglobins Proteins 0.000 claims description 12
- 230000003287 optical effect Effects 0.000 claims description 8
- 230000031700 light absorption Effects 0.000 claims description 5
- 238000000034 method Methods 0.000 claims 17
- 206010018910 Haemolysis Diseases 0.000 claims 6
- 230000008588 hemolysis Effects 0.000 claims 6
- 210000004369 blood Anatomy 0.000 claims 5
- 239000008280 blood Substances 0.000 claims 5
- 239000010836 blood and blood product Substances 0.000 claims 4
- 229940125691 blood product Drugs 0.000 claims 4
- 239000012528 membrane Substances 0.000 claims 3
- 210000000601 blood cell Anatomy 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 241000863032 Trieres Species 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 210000003617 erythrocyte membrane Anatomy 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 230000002503 metabolic effect Effects 0.000 claims 1
- 230000000877 morphologic effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14614509P | 2009-01-21 | 2009-01-21 | |
| US61/146,145 | 2009-01-21 | ||
| US12/690,916 | 2010-01-20 | ||
| US12/690,916 US8026102B2 (en) | 2009-01-21 | 2010-01-20 | Apparatus and method to characterize blood and red blood cells via erythrocyte membrane fragility quantification |
| PCT/US2010/021559 WO2010090848A2 (en) | 2009-01-21 | 2010-01-21 | Apparatus and method to characterize blood and red blood cells via erythrocyte membrane fragility quantification |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012515898A JP2012515898A (ja) | 2012-07-12 |
| JP2012515898A5 true JP2012515898A5 (enExample) | 2014-03-27 |
| JP5620407B2 JP5620407B2 (ja) | 2014-11-05 |
Family
ID=42337264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011546447A Expired - Fee Related JP5620407B2 (ja) | 2009-01-21 | 2010-01-21 | 赤血球膜脆弱性定量化により血液および赤血球を特徴付ける装置および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US8026102B2 (enExample) |
| EP (1) | EP2382464A4 (enExample) |
| JP (1) | JP5620407B2 (enExample) |
| CA (1) | CA2776545A1 (enExample) |
| WO (1) | WO2010090848A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
| WO2010103543A1 (en) * | 2009-03-09 | 2010-09-16 | Abhilasha Aswal | New vistas in inventory optimization under uncertainty |
| JP6388606B2 (ja) * | 2013-02-14 | 2018-09-12 | メタノミクス ヘルス ゲーエムベーハー | 生物学的サンプルの質を評価するための手段及び方法 |
| US10495629B2 (en) * | 2013-03-06 | 2019-12-03 | Blaze Medical Devices, Inc. | Bead mill and method of use |
| US10900954B2 (en) * | 2015-04-14 | 2021-01-26 | Blaze Medical Devices, Inc. | Method and system for inducing controlled and varied fluid stresses by bead oscillation |
| EP3455607B1 (en) | 2016-05-11 | 2022-07-20 | Nova Biomedical Corporation | Whole blood so2 sensor |
| US12332254B2 (en) | 2019-04-24 | 2025-06-17 | Cornell University | Systems, compositions, and methods for evaluating biomechanical properties of cells |
| WO2025212164A1 (en) | 2024-04-05 | 2025-10-09 | Massachusetts Institute Of Technology | Apparatus for high throughput assessment of cell properties, fragility or deformability |
| WO2025255145A1 (en) * | 2024-06-05 | 2025-12-11 | Fenwal, Inc. | System and method for determining red blood cell and buffy coat platelet quality based on plasma characterization |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4040742A (en) | 1976-08-09 | 1977-08-09 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare | Capillary flow method and apparatus for determination of cell osmotic fragility |
| US4178152A (en) | 1977-02-24 | 1979-12-11 | Sanki Engineering Ltd. | Cell fragility testing method and appliance therefor |
| US4402216A (en) | 1981-08-31 | 1983-09-06 | Nuclepore Corporation | Erythrocyte deformability monitor |
| US4491012A (en) | 1982-10-04 | 1985-01-01 | Nuclepore Corp. | Method for measuring erythrocyte deformability |
| DE3522186A1 (de) | 1985-06-21 | 1987-01-02 | Hoechst Ag | Messeinrichtung zum messen des verformungsvermoegens von roten blutkoerperchen |
| FR2825637B1 (fr) * | 2001-06-12 | 2003-09-12 | Biolog | Procede de determination et de suivi du vieillissement des poches de sang dans les etablissements de transfusion sanguine et les etablissements de soins |
| JP2004138561A (ja) * | 2002-10-18 | 2004-05-13 | Setsuo Takatani | 赤血球蓄積負荷状態測定方法および装置 |
| US7517453B2 (en) | 2003-03-01 | 2009-04-14 | The Trustees Of Boston University | Microvascular network device |
| US7629165B2 (en) * | 2004-01-22 | 2009-12-08 | Qualigen, Inc | Diagnostic device and method |
| CN101147052B (zh) * | 2005-03-25 | 2012-01-11 | 麻省理工学院 | 用于希耳伯特相位成像的系统和方法 |
| US7790464B2 (en) * | 2006-05-04 | 2010-09-07 | Blaze Medical Devices, LLC | Blood hemolysis analyzer |
-
2010
- 2010-01-20 US US12/690,916 patent/US8026102B2/en active Active
- 2010-01-21 WO PCT/US2010/021559 patent/WO2010090848A2/en not_active Ceased
- 2010-01-21 CA CA2776545A patent/CA2776545A1/en not_active Abandoned
- 2010-01-21 EP EP10738938A patent/EP2382464A4/en not_active Withdrawn
- 2010-01-21 JP JP2011546447A patent/JP5620407B2/ja not_active Expired - Fee Related
-
2011
- 2011-08-05 US US13/204,393 patent/US8263408B2/en active Active
- 2011-08-05 US US13/204,372 patent/US8268244B2/en active Active
-
2012
- 2012-03-06 US US13/412,691 patent/US20120178121A1/en not_active Abandoned
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