JP2012507033A5 - - Google Patents
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- Publication number
- JP2012507033A5 JP2012507033A5 JP2011534536A JP2011534536A JP2012507033A5 JP 2012507033 A5 JP2012507033 A5 JP 2012507033A5 JP 2011534536 A JP2011534536 A JP 2011534536A JP 2011534536 A JP2011534536 A JP 2011534536A JP 2012507033 A5 JP2012507033 A5 JP 2012507033A5
- Authority
- JP
- Japan
- Prior art keywords
- spectrum
- monoclonal antibody
- growth factor
- factor receptor
- epidermal growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 8
- 238000001228 spectrum Methods 0.000 claims 6
- 206010009944 Colon cancer Diseases 0.000 claims 4
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 4
- 102000001301 EGF receptor Human genes 0.000 claims 4
- 108060006698 EGF receptor Proteins 0.000 claims 4
- 239000003112 inhibitor Substances 0.000 claims 4
- 238000001819 mass spectrum Methods 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229960005395 cetuximab Drugs 0.000 claims 1
- 238000007635 classification algorithm Methods 0.000 claims 1
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims 1
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 claims 1
- 238000000816 matrix-assisted laser desorption--ionisation Methods 0.000 claims 1
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 238000010606 normalization Methods 0.000 claims 1
- 229960001972 panitumumab Drugs 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 238000007781 pre-processing Methods 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/321,394 US7858390B2 (en) | 2006-03-31 | 2009-01-20 | Selection of colorectal cancer patients for treatment with drugs targeting EGFR pathway |
| US12/321,394 | 2009-01-20 | ||
| PCT/US2009/006267 WO2010085234A1 (en) | 2009-01-20 | 2009-11-20 | Selection of colorectal cancer patients for treatment with drugs targeting egfr pathway |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012507033A JP2012507033A (ja) | 2012-03-22 |
| JP2012507033A5 true JP2012507033A5 (https=) | 2012-05-10 |
| JP4997345B2 JP4997345B2 (ja) | 2012-08-08 |
Family
ID=41571343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011534536A Expired - Fee Related JP4997345B2 (ja) | 2009-01-20 | 2009-11-20 | Ｅｇｆｒ経路を標的にする薬物による治療のための結腸直腸癌患者の選択 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7858390B2 (https=) |
| EP (1) | EP2347261B1 (https=) |
| JP (1) | JP4997345B2 (https=) |
| KR (1) | KR101131231B1 (https=) |
| AU (1) | AU2009338173B2 (https=) |
| CA (1) | CA2744394A1 (https=) |
| ES (1) | ES2392805T3 (https=) |
| IL (1) | IL211944A (https=) |
| TW (1) | TWI366671B (https=) |
| WO (1) | WO2010085234A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7736905B2 (en) | 2006-03-31 | 2010-06-15 | Biodesix, Inc. | Method and system for determining whether a drug will be effective on a patient with a disease |
| US7858390B2 (en) | 2006-03-31 | 2010-12-28 | Biodesix, Inc. | Selection of colorectal cancer patients for treatment with drugs targeting EGFR pathway |
| US7906342B2 (en) * | 2006-03-31 | 2011-03-15 | Biodesix, Inc. | Monitoring treatment of cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples |
| CN102770760A (zh) * | 2010-02-24 | 2012-11-07 | 佰欧迪塞克斯公司 | 利用质谱分析选择施用治疗剂的癌症患者 |
| US8914238B2 (en) | 2011-01-28 | 2014-12-16 | Biodesix, Inc. | Method for predicting breast cancer patient response to endocrine therapy |
| MX365418B (es) | 2012-06-26 | 2019-06-03 | Biodesix Inc | Metodo por espectros de masa para la seleccion y descarte de pacientes de cancer para el tratamiento con terapias generadoras de respuestas inmunitarias. |
| AU2013287262A1 (en) | 2012-07-05 | 2015-02-26 | Biodesix, Inc. | Method for predicting whether a cancer patient will not benefit from platinum-based chemotherapy agents |
| US10037874B2 (en) | 2014-12-03 | 2018-07-31 | Biodesix, Inc. | Early detection of hepatocellular carcinoma in high risk populations using MALDI-TOF mass spectrometry |
| WO2017011439A1 (en) | 2015-07-13 | 2017-01-19 | Biodesix, Inc. | Predictive test for melanoma patient benefit from pd-1 antibody drug and classifier development methods |
| CA3011719A1 (en) | 2016-01-21 | 2017-07-27 | Protein Dynamic Solutions Llc | Method and system for spectral data analysis |
| US11710539B2 (en) | 2016-02-01 | 2023-07-25 | Biodesix, Inc. | Predictive test for melanoma patient benefit from interleukin-2 (IL2) therapy |
| WO2017176423A1 (en) | 2016-04-08 | 2017-10-12 | Biodesix, Inc. | Classifier generation methods and predictive test for ovarian cancer patient prognosis under platinum chemotherapy |
| WO2018129301A1 (en) * | 2017-01-05 | 2018-07-12 | Biodesix, Inc. | Method for identification of cancer patients with durable benefit from immunotherapy in overall poor prognosis subgroups |
| US20210369775A1 (en) | 2017-12-15 | 2021-12-02 | Iovance Biotherapeutics, Inc. | Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof |
| US12094587B2 (en) | 2018-03-29 | 2024-09-17 | Biodesix, Inc. | Apparatus and method for identification of primary immune resistance in cancer patients |
| US20230386662A1 (en) * | 2020-10-19 | 2023-11-30 | B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University | Rapid and direct identification and determination of urine bacterial susceptibility to antibiotics |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101107765B1 (ko) | 2002-08-06 | 2012-01-25 | 싸이퍼젠 바이오시스템즈, 인코포레이티드 | 난소암의 검출을 위한 생물 마커의 용도 |
| AU2004248140A1 (en) | 2003-05-30 | 2004-12-23 | Cedars-Sinai Medical Center | Gene expression markers for response to EGFR inhibitor drugs |
| US20050267689A1 (en) | 2003-07-07 | 2005-12-01 | Maxim Tsypin | Method to automatically identify peak and monoisotopic peaks in mass spectral data for biomolecular applications |
| WO2005010492A2 (en) | 2003-07-17 | 2005-02-03 | Yale University | Classification of disease states using mass spectrometry data |
| US20090204334A1 (en) | 2004-03-30 | 2009-08-13 | Eastern Virginia Medical School | Lung cancer biomarkers |
| US20060029574A1 (en) | 2004-08-06 | 2006-02-09 | Board Of Regents, The University Of Texas System | Biomarkers for diagnosis, prognosis, monitoring, and treatment decisions for drug resistance and sensitivity |
| CA2612183C (en) * | 2005-06-28 | 2015-08-11 | Genentech, Inc. | Egfr and kras mutations |
| WO2007109571A2 (en) * | 2006-03-17 | 2007-09-27 | Prometheus Laboratories, Inc. | Methods of predicting and monitoring tyrosine kinase inhibitor therapy |
| US7736905B2 (en) * | 2006-03-31 | 2010-06-15 | Biodesix, Inc. | Method and system for determining whether a drug will be effective on a patient with a disease |
| US7858390B2 (en) | 2006-03-31 | 2010-12-28 | Biodesix, Inc. | Selection of colorectal cancer patients for treatment with drugs targeting EGFR pathway |
-
2009
- 2009-01-20 US US12/321,394 patent/US7858390B2/en not_active Expired - Fee Related
- 2009-11-20 JP JP2011534536A patent/JP4997345B2/ja not_active Expired - Fee Related
- 2009-11-20 WO PCT/US2009/006267 patent/WO2010085234A1/en not_active Ceased
- 2009-11-20 EP EP09795836A patent/EP2347261B1/en not_active Not-in-force
- 2009-11-20 CA CA2744394A patent/CA2744394A1/en not_active Abandoned
- 2009-11-20 ES ES09795836T patent/ES2392805T3/es active Active
- 2009-11-20 AU AU2009338173A patent/AU2009338173B2/en not_active Ceased
- 2009-11-20 KR KR1020117007641A patent/KR101131231B1/ko not_active Expired - Fee Related
- 2009-12-16 TW TW098143181A patent/TWI366671B/zh not_active IP Right Cessation
-
2011
- 2011-03-24 IL IL211944A patent/IL211944A/en not_active IP Right Cessation
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