JP2012148015A - Package for diagnosis - Google Patents

Abstract

PROBLEM TO BE SOLVED: To facilitate calibration without requiring user to carry out complicated works relating to calibration.SOLUTION: The package for diagnosis 1 includes a tray 70, a probe 10 stored in the tray 70, a target 30 for calibration to be used for calibration, and a bag 90 wrapping the probe 10, the target 30 for calibration and the tray 70. The tray 70 includes a tray body 71, and a cable storage 74, a connector storage 73 and a tip storage 75 each provided being recessed on the upper surface of the tray body 71. The probe 10 includes the cable body part 13 stored in the cable storage 74, a connector 11 stored in connector storage 73, and the optical receiver 12 stored in the tip storage 75. The target 30 for calibration is located in the tip storage 75 so as to face the tip of the optical receiver 12.

Description

  The present invention relates to a diagnostic package including a probe, a calibration target, a tray, and a packaging bag.

  Various techniques have been proposed and put into practical use for observing and detecting a lesion state of a living tissue. In particular, endoscopes are widely used. The endoscope is inserted into the body lumen, the observation site of the biological tissue is illuminated by the illumination light emitted from the distal end portion of the endoscope, and the observation site of the biological tissue is photographed by the distal end portion of the endoscope. An image photographed by the endoscope is transmitted to an output device such as a display device and a printing device, and is output from the output device.

  The color tone of the photographed image is affected by the combination of the endoscope and the illumination light, the usage time, and the like. Therefore, there may be a difference between the color tone of the photographed image and the actual color tone. In order to reduce such color misregistration, it is necessary to adjust white balance.

Patent Documents 1 to 3 disclose jigs used for white balance adjustment. Patent Document 4 discloses a white balance adjustment system.
In the technique described in Patent Document 1, a jig is provided like a cap, and the white balance is adjusted by covering the tip of the endoscope with the jig.
In the technique described in Patent Document 2, a rotating disk is attached to the tip of a cylindrical member of a jig, and a plurality of color charts are provided on the rotating disk. The color chart facing the distal end of the endoscope can be switched by rotating the turntable with the endoscope inserted into the cylindrical member.
In the technique described in Patent Document 3, both ends of the first tubular member are open, and the first tubular member is inserted into the bottomed tubular second tubular member. When the endoscope is inserted into the first tubular member, the second tubular member is driven in the axial direction by the driving device, and the distance between the bottom of the second tubular member and the distal end of the endoscope is automatically adjusted.
The technology described in Patent Document 4 automatically adjusts the white balance by photographing a white portion displayed on a display monitor with an endoscope.

  In addition to image diagnosis using an endoscope, a technique for making a diagnosis using fluorescence has been proposed. In order to make a diagnosis using fluorescence, the measurement site is irradiated with excitation light so that fluorescence is emitted from the measurement site of biological tissue, and the wavelength and intensity of the generated fluorescence are analyzed. In order to make such a diagnosis, a probe has been developed and used for diagnosis of a disease state (for example, disease type or infiltration range) such as degeneration of a living tissue or cancer.

  This type of probe includes a light projecting optical fiber, a light receiving optical fiber, and a lens. Excitation light emitted from the tip of the light projecting optical fiber is projected onto the measurement site of the living tissue by the lens, and fluorescence emitted from the measurement site of the living tissue is projected onto the tip of the light receiving optical fiber by the lens. The fluorescence incident on the light receiving optical fiber is transmitted to the spectrum analyzing apparatus by the light receiving optical fiber, and the spectrum analysis of the fluorescence is performed by the apparatus.

  Generally, there are individual differences in the characteristics of optical fibers and lenses for each probe. For this reason, the analysis results obtained by the spectrum analyzer differ from probe to probe. Therefore, it is necessary to perform calibration before making a diagnosis using the probe. However, the work related to calibration is complicated and cumbersome, and it is necessary to avoid as much as possible to force such a calibration work to the user in the medical field.

JP 2006-223591 A JP 2005-40210 A JP 2008-86697 A JP 2004-40353 A

By the way, it is conceivable to use the jigs described in Patent Documents 1 to 3 for probe calibration. However, these jigs are large-scale. A simple jig is desired for the probe calibration.
In addition, the jigs described in Patent Documents 1 to 3 are based on the premise that they are repeatedly used. If the color chart or the like deteriorates over time, accurate calibration and white balance adjustment cannot be performed. Even the technique described in Patent Document 4 is affected by the degree of color development of the display monitor, aging, or the use environment, and accurate calibration and white balance adjustment cannot be performed.

  Therefore, the problem to be solved by the present invention is to enable easy calibration without forcing the user to perform complicated work related to calibration. The problem to be solved by the present invention is to enable calibration of a probe with a simple configuration. The problem to be solved by the present invention is to eliminate the influence of aging and the like and to perform more accurate calibration.

In order to solve the above problems, the diagnostic packaging according to the present invention is:
A tray,
A probe housed in the tray for transmitting, projecting and receiving light;
A calibration target that is irradiated with light emitted from the probe during calibration of the probe;
A packaging bag enclosing the probe, the calibration target, and the tray;
The tray has a tray main body, a ring-shaped cable storage portion recessed in the upper surface of the tray main body, and a recess formed in the upper surface of the tray main body, connected to the cable storage portion, and the cable from the cable storage portion to the cable A connector storage portion extending in a tangential direction of the storage portion; a tip storage portion recessed in the upper surface of the tray main body, connected to the cable storage portion, and extending from the cable storage portion in a tangential direction of the cable storage portion; Have
The probe is connected to a cable main body for transmitting light, a connector for inputting / outputting light, and connected to a distal end of the cable main body for light projection and light reception. A light receiving and receiving unit,
The light projecting / receiving unit is stored in the tip storage unit, the cable body unit is stored in the cable storage unit, and the connector is stored in a connector storage unit;
The calibration target is arranged in the tip storage portion so as to face the tip of the light projecting / receiving portion.

  Preferably, the diagnostic package further includes a light shielding material fitted into the tip portion storage portion from above the light projecting / receiving portion.

  Preferably, the diagnostic package further includes a light-shielding sheet that is attached to an inner wall of the tip portion storage portion and encloses the light projecting and receiving portion.

  Preferably, the diagnostic package is disposed in the tip portion storage portion so as to face the tip of the light projecting / receiving portion, and is disposed between the calibration target and the light projecting / receiving portion. A calibration target is further provided.

Preferably, the diagnostic package is
A strip that penetrates the light shielding material from the tip portion storage portion to the outside of the tip portion storage portion;
A second calibration target that is affixed to the strip and disposed in the distal end housing portion so as to face the distal end of the light projecting / receiving unit, and disposed between the calibration target and the light projecting / receiving unit. And further comprising.

Preferably, the diagnostic package is
A strip penetrating the light shielding sheet and the wall of the tip portion storage portion from the tip portion storage portion to the outside of the tip portion storage portion;
A second calibration target that is affixed to the strip and disposed in the distal end housing portion so as to face the distal end of the light projecting / receiving unit, and disposed between the calibration target and the light projecting / receiving unit. And further comprising.

  Preferably, the color of the calibration target is different from the color of the second calibration target.

  Preferably, the color of the calibration target is black, and the color of the second calibration target is white.

  Preferably, the calibration target is attached to the inner wall of the tip portion storage portion.

Preferably, the diagnostic package is
A cover sheet that covers the tip storage part from above the light projecting and receiving part;
A flap that hangs between the calibration target and the light projecting / receiving unit in the tip portion storage unit from the cover sheet,
The calibration target is attached to the flap.

Preferably, the diagnostic package is
A cover sheet that covers the tip storage part from above the light projecting and receiving part;
A flap that hangs between the calibration target and the light projecting / receiving unit in the tip portion storage unit from the cover sheet,
The shading material is adhered to the cover sheet;
The calibration target is attached to the flap.

Preferably, the diagnostic package is
A cover sheet that covers the tip storage part from above the light projecting and receiving part;
A flap that hangs between the calibration target and the light projecting / receiving unit in the tip portion storage unit from the cover sheet,
The strip penetrates the cover sheet;
The shading material is adhered to the cover sheet;
The calibration target is attached to the flap.

Preferably, the tray further includes a stopper protruding from the inner wall of the tip portion storage portion,
The tip of the light projecting / receiving portion abuts on the stopper,
The calibration target is disposed in the tip storage portion on the opposite side of the light projecting / receiving portion with respect to the stopper.

Preferably, the diagnostic package is further provided with a stopper projecting from the lower surface of the cover sheet and projecting into the tip portion storage portion,
The tip of the light projecting / receiving portion abuts on the stopper,
The calibration target is disposed in the tip storage portion on the opposite side of the light projecting / receiving portion with respect to the stopper.

According to the present invention, since the calibration target is disposed in the tip storage portion so as to face the tip of the light projection / reception unit, calibration can be performed without taking out the light projection / reception unit from the tip storage portion. It can be carried out. For this reason, it is not necessary to require the user to perform special work / load.
Further, since the probe and the calibration target are bundled and wrapped in a packaging bag, it is not necessary to prepare a large-scale adjustment jig separately.
Further, since the probe and the calibration target are bundled and wrapped in the packaging bag, the new calibration target can be used for calibration. Therefore, there is almost no secular change of the calibration target, and accurate calibration can be performed.

It is an external appearance perspective view of the diagnostic packaging in 1st embodiment of this invention. It is a disassembled perspective view of the diagnostic package in the same embodiment. It is a top view of the probe in the embodiment. 2 is a partial cross-sectional view of a tray in the same embodiment. FIG. It is a partial exploded perspective view of the diagnostic packaging in the same embodiment. It is a disassembled perspective view of the diagnostic package in the same embodiment. It is a perspective view of the base unit in the embodiment. It is a block diagram of the base unit in the embodiment. It is the perspective view which showed the use condition of the diagnostic packaging in the same embodiment. It is the flowchart which showed the flow of the process performed by the computer of the base unit in the embodiment. It is a one part disassembled perspective view of the diagnostic packaging in 2nd embodiment of this invention. 2 is a partial cross-sectional view of a tray in the same embodiment. FIG. It is a partial sectional view of a tray in a third embodiment of the present invention. 2 is a partial cross-sectional view of a tray in the same embodiment. FIG. It is the flowchart which showed the flow of the process performed by the computer of the base unit in the embodiment. It is sectional drawing of a part of tray in 4th embodiment of this invention.

  EMBODIMENT OF THE INVENTION Below, the form for implementing this invention is demonstrated using drawing. However, the embodiments described below are given various technically preferable limitations for carrying out the present invention, but the scope of the present invention is not limited to the following embodiments and illustrated examples.

<First embodiment>
[Outline of diagnostic packaging]
FIG. 1 is an external perspective view of the diagnostic packaging 1. FIG. 2 is an exploded perspective view of the diagnostic packaging 1. As shown in FIGS. 1 and 2, the diagnostic package 1 includes a probe 10, a calibration target 30, a light shielding sheet 40, a light shielding cover 50, a tray 70, a cover 80, a packaging bag 90, and the like.

  The probe 10 is a cable material that transmits, projects, and receives light. The proximal end portion of the probe 10 is a connector 11 for inputting / outputting light, the distal end portion of the probe 10 is a light projecting / receiving portion 12 for projecting / receiving light, and an intermediate portion of the probe 10 is projected with the connector 11. This is a cable body 13 that transmits light between the light receivers 12. The light projecting / receiving unit 12 is connected to the distal end of the cable body 13, and the connector 11 is connected to the proximal end of the cable body 13.

  When the probe 10 is used, the connector 11 is connected to the base unit 100 (shown in FIGS. 7 and 8; details of the base unit 100 will be described later), and the light projecting / receiving unit 12 is inserted into the lumen. Excitation light emitted from the light source of the base unit 100 is input to the connector 11 at the proximal end portion of the probe 10, and the input excitation light is transmitted to the light projecting / receiving portion 12 at the distal end portion by the cable body portion 13. The excited excitation light is irradiated from the light projecting / receiving unit 12 to the measurement site of the living tissue in the lumen. The measurement site emits fluorescence by excitation light. The fluorescence emitted from the measurement site is received by the light projecting / receiving unit 12, and the received fluorescence is transmitted to the connector 11 at the base end by the cable body 13, and the transmitted fluorescence is transmitted from the connector 11 to the base unit 100. Is output. The base unit 100 performs spectral analysis of the fluorescence input to the base unit 100. Using the probe 10 as described above, an optical diagnosis is performed by the probe 10.

  This probe 10 is disposable. That is, from the viewpoint of hygiene, the probe 10 that is once inserted into the lumen is not reused.

  The calibration target 30 is used before the probe 10 is inserted into a lumen and used. When using the calibration target 30, the light projecting / receiving part 12 of the probe 10 is directed toward the calibration target 30, and the connector 11 of the probe 10 is connected to the base unit 100. Then, light of known standard intensity emitted from the light source of the base unit 100 is projected from the light projecting / receiving unit 12 of the probe 10 onto the calibration target 30, and the reflected light is received by the light projecting / receiving unit 12 and received. The transmitted light is transmitted to the base unit 100 by the cable body 13 and the connector 11. In the base unit 100, the intensity of the input light is measured, and calibration is performed by taking into account the difference between the measured intensity and the known standard intensity.

〔probe〕
The probe 10 will be specifically described.
FIG. 3 is a plan view of the probe 10. As shown in FIG. 3, the probe 10 includes a light projecting optical fiber 14, a light receiving optical fiber 15, an illumination optical fiber 16, a lens 17, an illumination lens 18, a holder 19, a connector housing 21, a tube 25, and the like. Prepare.

  The tube 25 is provided in a tubular shape. The tube 25 forms the outer peripheral wall of the probe 10. The tube 25 has water barrier properties and flexibility. The connector housing 21 is connected to the proximal end of the tube 25, and the holder 19 is connected to the distal end of the tube 25.

  An identifier 26 is attached to the probe 10. The location to which the identifier 26 is attached is, for example, the connector housing 21, the tube 25, or the holder 19. The identifier 26 is, for example, an ID, a serial number, a manufacturing number, or a lot number.

Connection pins 22 to 24 project from the end face of the connector housing 21.
The holder 19 has an internal space, and the internal space communicates with the hollow of the tube 25. A light projecting / receiving window 20 is provided on the front end surface of the holder 19. The lens 17 and the illumination lens 18 are accommodated in the internal space of the holder 19 and are fixed to the holder 19. The lens 17 faces the light projecting / receiving window 20 and the illumination lens 18 faces the light projecting / receiving window 20.

The light projecting optical fiber 14, the light receiving optical fiber 15, and the illumination optical fiber 16 are passed through the tube 25 from the connector housing 21 to the holder 19.
The proximal end portions of the light projecting optical fiber 14, the light receiving optical fiber 15, and the illumination optical fiber 16 are fixed to the connector housing 21 inside the connector housing 21. A portion near the base end of the light projecting optical fiber 14 is passed through the connection pin 22, and the base end of the light projecting optical fiber 14 is exposed at the projecting end of the connection pin 22. Similarly, the proximal end portions of the light receiving optical fiber 15 and the illumination optical fiber 16 are attached to the connection pins 23 and 24, respectively. The light projecting optical fiber 14 guides the excitation light incident on the proximal end thereof to the distal end. The light receiving optical fiber 15 guides the fluorescence incident on the tip thereof to the base end. The illumination optical fiber 16 guides illumination light (for example, visible light) incident on the proximal end thereof to the distal end.

  The tip of the light projecting optical fiber 14 is opposed to the lens 17, and the tip of the light receiving optical fiber 15 is also opposed to the lens 17. The lens 17 is a collimating lens. That is, the lens 17 projects the excitation light emitted from the tip of the light projecting optical fiber 14 to the front of the tip of the probe 10 as substantially parallel light. The excitation light projected by the lens 17 passes through the light projection / receiving window 20. A measurement site of biological tissue arranged in front of the tip of the probe 10 is excited by excitation light and emits fluorescence. Fluorescence emitted from the measurement site of the living tissue passes through the light projecting and receiving window 20 and is collected by the lens 17 at the tip of the light receiving optical fiber 15.

  The tip of the illumination optical fiber 16 is opposed to the illumination lens 18. Illumination light emitted from the tip of the illumination optical fiber 16 is projected forward of the tip of the probe 10 by the illumination lens 18.

  A portion including the connector housing 21, the connection pins 22 to 24, and the proximal end portions of the optical fibers 14 to 16 corresponds to the connector 11 of the probe 10. A portion including the lens 17, the illumination lens 18, the holder 19, and the light projecting / receiving window 20 corresponds to the light projecting / receiving unit 12 of the probe 10. The central portion of the tube 25 and the optical fibers 14 to 16 corresponds to the cable main body 13 that connects the connector 11 and the light projecting / receiving unit 12.

  The light projecting / receiving window 20 may be provided on the side surface of the holder 19. In that case, a mirror is disposed inside the holder 19 and in front of the lens 17, and excitation light projected by the lens 17 is reflected by the mirror toward the light projecting / receiving window 20. The fluorescence emitted from the measurement site of the living tissue and transmitted through the light projecting and receiving window 20 is reflected toward the lens 17 by the mirror.

  An imaging camera may be built in the holder 19. In that case, the periphery of the holder 19 is photographed by the imaging camera, and an image photographed by the imaging camera is transferred to the base unit 100. Since the probe 10 is disposable, it is preferable that the imaging camera is not incorporated as described above.

  Although the number of optical fibers provided in the above probe 10 is 3, the number of optical fibers may be 1 or 2, or may be 4 or more. When the number of optical fibers is 2, it is preferable that there is no illumination optical fiber 16 and the light projecting optical fiber 14 is used both for pumping the excitation light and for guiding the illumination light. When the number of optical fibers is 1, it is preferable that the light projecting optical fiber 14 is also used for exciting light guiding, fluorescence guiding, and illumination light guiding.

〔tray〕
The tray 70 will be specifically described.
As shown in FIG. 2, the tray 70 has a box-shaped tray body 71 having an open bottom surface. The tray body 71 is obtained by processing a thin plate material made of resin, paper, or metal into a box shape. The tray body 71 has chemical resistance and heat resistance, and the properties of the tray body 71 do not change even under a sterilization gas environment and a high temperature environment.

  A probe storage recess 72 is provided in the upper surface of the tray body 71. The probe 10 is stored in the probe storage recess 72.

  The probe storage recess 72 includes a connector storage portion 73 in which the connector 11 is stored, a cable storage portion 74 in which the cable main body portion 13 is stored, and a tip end storage portion 75 in which the light projecting / receiving portion 12 is stored. . The cable storage portion 74 is a ring-shaped recess that is recessed in the upper surface of the tray body 71. The connector storage portion 73 is a concave portion provided in the upper surface of the tray main body 71. The connector housing 73 is connected to the cable housing 74 and extends in the tangential direction of the cable housing 74. The front end storage portion 75 is a recess provided in the tray body 71. The distal end storage portion 75 is connected to the cable storage portion 74 and extends in the tangential direction of the cable storage portion 74.

  FIG. 4 is a cross-sectional view of the tip storage portion 75. The tray 70 further has a stopper 77. The stopper 77 is protruded from the inner wall of the tip portion storage portion 75. Specifically, the stopper 77 is formed on the bottom of the tip portion storage portion 75 at a position away from the abutting surface 76 of the tip portion storage portion 75.

[Shading sheet]
The light shielding sheet 40 will be specifically described.
FIG. 5 is an exploded perspective view of the distal end storage portion 75 and its surroundings.
As shown in FIGS. 4 and 5, the light shielding sheet 40 is attached to the inner wall of the distal end storage portion 75. The light shielding sheet 40 is made of an elastic polyurethane foam material (maltoprene). The shading sheet 40 may be flocked. The stopper 77 penetrates the light shielding sheet 40 and protrudes from the light shielding sheet 40.

  The light shielding sheet 40 has chemical resistance and heat resistance, and the properties of the light shielding sheet 40 do not change even under a sterilization gas environment and a high temperature environment.

[Calibration target]
The calibration target 30 will be specifically described.
As shown in FIGS. 4 and 5, the calibration target 30 is disposed in the distal end portion storage portion 75. The installation position of the calibration target 30 is closer to the abutting surface 76 of the distal end storage portion 75 than the stopper 77. Specifically, the calibration target 30 is attached to the abutting surface 76 of the tip portion storage portion 75. The calibration target 30 may be directly attached to the abutting surface 76, or may be attached to the abutting surface 76 via the light shielding sheet 40.

  The calibration target 30 is colored, and the color of the calibration target 30 is, for example, black, white, red, green, blue, yellow, magenta, or cyan. The calibration target 30 may be a uniform single color or an array of various colors such as a so-called color chart.

  The calibration target 30 is, for example, a standard color chart such as Munsell color, a standard color plate (for example, a standard white plate), a standard fluorescent sample, or a Raman standard sample. The calibration target 30 may include a base material and a standard color sheet (for example, a Munsell color sheet) attached to the base material. The calibration target 30 may be made of barium sulfate. Preferably, a product obtained by forming barium sulfate in a tablet shape is used as the calibration target 30.

  The calibration target 30 may not be attached to the abutting surface 76 of the tip storage portion 75, but the abutting surface 76 may be colored and the abutting surface 76 may function as the calibration target 30. When the abutting surface 76 functions as the calibration target 30, the light shielding sheet 40 is stuck to the inner wall of the tip portion storage portion 75 except for the abutting surface 76.

  Moreover, the part stuck to the contact surface 76 among the light shielding sheets 40 may be colored, and the part may function as the calibration target 30.

  The calibration target 30 has chemical resistance and heat resistance, and the properties of the calibration target 30 do not change even under a sterilization gas environment and a high temperature environment.

[Shading cover]
The light shielding cover 50 will be specifically described.
As shown in FIGS. 4 and 5, the light shielding cover 50 covers the tip portion storage portion 75 from above the tip portion storage portion 75, and the tip portion storage portion 75 is covered with the light shielding cover 50. The light shielding cover 50 has a light shielding property.

  The light shielding cover 50 includes a cover sheet 51, a light shielding material 52, and a stopper 53. The light shielding material 52 is formed by forming a polyurethane foam material (maltoprene) having elasticity into a thin plate shape. A light shielding material 52 is adhered to the lower surface of the cover sheet 51. The size of the cover sheet 51 is larger than the size of the light shielding material 52, and the peripheral portion of the cover sheet 51 protrudes from the edge of the light shielding material 52. A stopper 53 is projected on the lower surface of the cover sheet 51. The stopper 53 penetrates the light shielding material 52 and protrudes from the light shielding material 52.

  The cover sheet 51 covers the tip portion storage portion 75 from above the tip portion storage portion 75, and the peripheral portion of the cover sheet 51 is placed on the upper surface of the tray body 71 outside the tip portion storage portion 75. The light shielding material 52 is fitted into the tip portion storage portion 75 so as to be separated from the bottom of the tip portion storage portion 75. The periphery of the light shielding material 52 contacts the light shielding sheet 40, and a space surrounded by the light shielding material 52 and the light shielding sheet 40 is formed.

  In a state where the distal end portion storage portion 75 is covered with the light shielding cover 50, the stopper 53 protrudes into the distal end portion storage portion 75. The stopper 53 is separated from the abutting surface 76 of the tip portion storage portion 75. The stopper 53 and the stopper 77 are opposed to each other vertically, and the protruding end of the stopper 53 and the protruding end of the stopper 77 are separated from each other. One of the stopper 53 and the stopper 77 may be omitted.

  On the upper surface of the light shielding cover 50, that is, the upper surface of the cover sheet 51, a caution note is printed or stamped. The content of the notice is that it is prohibited to remove the light shielding cover 50 before the calibration process.

  The light shielding cover 50, the cover sheet 51, the light shielding material 52, and the stopper 53 have chemical resistance and heat resistance, and the light shielding cover 50, the cover sheet 51, the light shielding material 52, and the stopper 53 are also in a sterile gas environment and a high temperature environment. The property does not change.

[Probe storage state]
FIG. 6 is a perspective view showing a state where the probe 10 is stored on the tray 70. As shown in FIG. 6, the probe 10 is housed in the probe housing recess 72 so as to be fitted into the probe housing recess 72. Specifically, the light projecting / receiving portion 12 of the probe 10 is stored in the tip portion storage portion 75 so as to be fitted into the tip portion storage portion 75. The cable body 13 of the probe 10 is housed in the cable housing 74 so as to be fitted into the cable housing 74 in a spirally wound state. The cable main body 13 is spirally wound so that the connector 11 side overlaps the light projecting / receiving unit 12 side. The connector 11 of the probe 10 is housed in the connector housing portion 73 so as to be fitted into the connector housing portion 73. As described above, the probe 10 is housed in the probe housing recess 72, so that the connector 11 of the probe 10 can be easily taken out first as described later.

  Conversely, the cable main body 13 may be spirally wound so that the light projecting / receiving portion 12 side overlaps the connector 11 side and stored in the cable storage portion 74. Depending on the elasticity of the cable main body 13, the cable main body 13 may protrude from the cable storage portion 74, so that the light projecting / receiving portion 12 side of the cable main body 13 overlaps the connector 11 side, so that the connector 11 It is possible to prevent the cable main body portion 13 from jumping out of the cable storage portion 74 during removal. In any case, considering the elasticity and length of the cable body 13 in a comprehensive manner, the light projecting / receiving part 12 side of the cable body 13 is overlaid on the connector 11 side, or the connector 11 side is projected. Select whether to superimpose on the light receiving unit 12 side.

  Since the probe 10 is housed in the probe housing recess 72 as described above, the probe 10 is held by the tray body 71, and the probe 10 can be protected from impact or the like.

  One or a plurality of elastic protrusions may be provided on the side surface of the probe storage recess 72, and when the probe 10 is stored in the probe storage recess 72, the elastic protrusion may be compressed by the probe 10. As a result, the probe 10 is supported by the elastic protrusion, and the probe 10 is unlikely to be detached from the probe storage recess 72.

  As shown in FIG. 4, in a state where the light projecting / receiving unit 12 is housed in the tip end housing unit 75, the light projecting / receiving unit 12 is wrapped by the light shielding sheet 40, and the circumferential surface of the light projecting / receiving unit 12 is the light shielding sheet 40. The light shielding sheet 40 is slightly compressed by the light projecting / receiving unit 12. The peripheral portion of the front end surface (projection light receiving window 20) of the light projecting / receiving unit 12 is in contact with the stopper 77, and the front end surface of the light projecting / receiving unit 12 is separated from the abutting surface 76 of the front end storage unit 75 and the calibration target 30. ing.

  The front end storage portion 75 is covered with the light shielding cover 50, and the light projecting / receiving portion 12 is covered with the light shielding cover 50. Specifically, the light shielding material 52 of the light shielding cover 50 is fitted into the tip end housing portion 75 from above the light projecting / receiving portion 12. The circumferential surface of the light projecting / receiving unit 12 is in contact with the light shielding material 52, and the light shielding material 52 is slightly compressed by the light projecting / receiving unit 12.

  The peripheral portion of the front end surface (projection light receiving window 20) of the light projecting / receiving unit 12 contacts the stopper 53, and the front end surface of the light projecting / receiving unit 12 is separated from the abutting surface 76 of the front end storage unit 75 and the calibration target 30. ing.

  The front end surface of the light projecting / receiving unit 12 (particularly, the light projecting / receiving window 20) faces the calibration target 30 through a gap between the stopper 53 and the stopper 77. The optical axis of the excitation light projected from the light projecting / receiving unit 12 passes between the stopper 53 and the stopper 77. The optical axis of the excitation light projected from the light projecting / receiving unit 12 is orthogonal to the calibration target 30. By the stopper 53 and the stopper 77, the distance from the front end surface of the light projecting / receiving unit 12 to the calibration target 30 is appropriately set.

  The light projecting / receiving unit 12 is packed in a space surrounded by the light shielding material 52 and the light shielding sheet 40, but not all of the front end surface of the light projecting / receiving unit 12 is covered. Light projection / light reception is not hindered by the light shielding material 52, the light shielding sheet 40, the stopper 53 and the stopper 77.

  Since the light projecting / receiving unit 12 is surrounded by the light shielding material 52 and the light shielding sheet 40, the light projecting / receiving unit 12 is housed in the distal end housing unit 75 in a light-tight state. The space between the front end surface of the light projecting / receiving unit 12 and the calibration target 30 is also shielded by the light shielding material 52 and the light shielding sheet 40. Further, the light shielding material 52 and the light shielding sheet 40 function as a cushion, and an impact load at the time of conveyance or the like is attenuated by the light shielding material 52 and the light shielding sheet 40, so that the light projecting and receiving unit 12 is protected.

〔cover〕
The cover 80 will be specifically described. As shown in FIGS. 2, 4, and 6, the cover 80 covers the top surface of the tray body 71 from above the light shielding cover 50, and the probe receiving recess 72 is covered with the cover 80. The stored probe 10 is covered with a cover 80 to protect the probe 10. The cover 80 has chemical resistance and heat resistance, and the properties of the cover 80 do not change even under a sterilized gas environment and a high temperature environment.

  A convex portion 81 is formed on the lower surface of the cover 80 so as to overlap the connector accommodating portion 73 and the cable accommodating portion 74 of the probe accommodating concave portion 72, and the convex portion 81 is above the cable main body portion 13 and the connector 11 of the probe 10. To the connector housing portion 73 and the cable housing portion 74 of the probe housing recess 72. Thereby, the probe 10 is fixed firmly.

[Packaging bag]
The packaging bag 90 will be specifically described.
As shown in FIGS. 1, 2, and 6, the packaging bag 90 wraps the probe 10, the tray 70, the cover 80, and the like, and the probe 10, the tray 70, the cover 80, and the like are accommodated in the packaging bag 90. Of course, also in the packaging bag 90, the probe 10 is housed in the probe housing recess 72, the tip surface of the light projecting / receiving unit 12 (particularly, the light projecting / receiving window 20) faces the calibration target 30, and the probe housing recess 72 The tip storage portion 75 is covered with a light shielding cover 50.

  FIG. 1 shows a state in which the probe 10, the tray 70, the cover 80, and the like are packaged by the packaging bag 90. As shown in FIG. 1, the packaging bag 90 is sealed.

  The packaging bag 90 preferably has a light shielding property. It is preferable that the packaging bag 90 has airtightness. The packaging bag 90 has chemical resistance, and the properties of the packaging bag 90 do not change even in a sterilized gas environment. The space in the packaging bag 90 is sealed by joining the mouth of the packaging bag 90 by heat welding using a center sealing machine or the like.

  Although the packaging bag 90 has gas permeability, micropores formed in the packaging body 90 are very small, and micrometer-order bacteria and dust do not penetrate the packaging body 90.

  The packaging bag 90 is sterilized. Specifically, the probe 10, the adjustment jig 30, the tray 70, the cover 80, and the like are packaged by the packaging bag 90, and the packaging bag 90 is sealed, and the packaging bag 90 is sterilized at a high temperature in a high-temperature furnace. The packaging bag 90 is sterilized by being exposed to the gas atmosphere.

  A pocket may be provided outside the packaging bag 90. Instructions, specifications, etc. are inserted into the pocket.

[Base unit]
The base unit 100 will be described.
FIG. 7 is a perspective view of the base unit 100. FIG. 8 is a block diagram of the base unit 100. As shown in FIGS. 7 and 8, the base unit 100 includes a housing 101, a CPU 103, a RAM 104, a ROM 105, a signal processing unit 106, a photometric unit 107, light emission control units 108 and 110, an illumination light source 109, a light source 111, and an interface 112. And a sensor 113 and the like.

  The CPU 103, RAM 104, ROM 105, signal processing unit 106, photometry unit 107, light emission control units 108 and 110, illumination light source 109, light source 111, interface 112, and sensor 113 are built in the housing 101.

  A connection portion 102 is provided on the front surface of the housing 101. The connector 11 of the probe 10 is connected to the connection unit 102. When the connector 11 of the probe 10 is connected to the connection portion 102, the base end of the light projecting optical fiber 14 is connected to the light source 111 via the optical waveguide, and the base end of the light receiving optical fiber 15 is connected via the optical waveguide. Connected to the photometric unit 107, the proximal end of the illumination optical fiber 16 is connected to the illumination light source 109 via an optical waveguide.

  The sensor 113 is attached to the connection unit 102. The sensor 113 detects that the connector 11 is connected to the connection unit 102 and outputs a detection signal to the CPU 103. The sensor 113 is, for example, an infrared sensor, a micro switch, or a proximity sensor.

  The ROM 105 stores a program that can be read by the CPU 103. The CPU 103 executes a program stored in the ROM 105, controls the signal processing unit 106, the photometry unit 107, the light emission control units 108 and 110, and the interface 112 according to the program, and transfers signals and data between them. Do. The RAM 104 provides a work area for the CPU 103.

  The CPU 103 performs calculations related to calibration according to the program, and records the calculation results (correction coefficients) in the RAM 104. The CPU 103 causes the photometry unit 107 to reflect the calculation result (correction coefficient).

  The interface 112 transfers data between the CPU 109 and the computer 114 in accordance with a command from the CPU 109. An input device (for example, a keyboard and a mouse) 115 and a display monitor 116 are connected to the computer 114.

  The light emission control unit 110 controls the light source 111 according to a command from the CPU 103. The light emission control unit 110 controls the light emission timing, the turn-off timing, the light emission intensity, and the like of the light source 111. Similarly, the light emission control unit 108 controls the illumination light source 109 in accordance with a command from the CPU 103.

  The illumination light source 109 emits visible light as illumination light. The light source 111 generates excitation light (for example, X-rays, ultraviolet rays, visible rays, or electromagnetic waves). Further, the light emission control unit 110 controls the light source 111 to adjust the wavelength of the excitation light emitted by the light source 111.

The photometry unit 107 separates the fluorescence input from the light receiving optical fiber 15 of the probe 10 and measures the intensity of the fluorescence for each wavelength. The photometry unit 107 measures the intensity of the fluorescence without splitting the fluorescence input from the light receiving optical fiber 15 of the probe 10. Hereinafter, the intensity for each wavelength measured by the photometric unit 107 is referred to as spectrum data, and the intensity measured without being spectrally separated by the photometric unit 107 is referred to as intensity data.
The photometry unit 107 measures spectral data and intensity data in a state where the calculation result (correction coefficient) input from the CPU 103 is reflected, and measures spectral data and intensity data in a state where the calculation result (correction coefficient) is not reflected. Also do.
Spectrum data and intensity data measured by the photometry unit 107 are transferred to the signal processing unit 106 by the CPU 103 or transferred to the computer 114 by the CPU 103 and the interface 112.
The signal processing unit 106 performs signal processing of spectrum data and intensity data.

[How to handle diagnostic packaging and operation of base unit]
The handling method of the diagnostic packaging 1 and the operation of the base unit 100 will be described.
FIG. 9 is a perspective view showing a usage state of the diagnostic packaging 1. FIG. 10 is a flowchart showing the flow of processing performed by the CPU 103 according to the program.

  First, the CPU 103 waits until a detection signal is input from the sensor 113 (step S1: No).

  At that time, the user opens the packaging bag 90 and takes out the probe 10, the light shielding cover 50 and the cover 80 together with the tray 70 from the packaging bag 90. Next, the user removes the cover 80 from the tray 70. Next, the user reads the identifier 26 attached to the probe 10 and inputs the same value as the identifier 26 with the input device 115. The input identifier is transferred from the computer 114 to the CPU 103, and the CPU 103 records the input identifier in the RAM 104.

  Next, the user takes out the connector 11 of the probe 10 from the connector storage portion 73. Since the cable body 13 is spirally wound so that the connector 11 side of the cable body 13 overlaps the light projecting / receiving part 12 side of the cable body 13, the user can easily take out the connector 11.

  If the packaging bag 90 has a light-shielding property, the user may store the portion other than the connector 11 side of the probe 10 together with the tray 70 in the packaging bag 90 after taking out the connector 11 from the connector storage portion 73. . Thereby, the light projecting / receiving part 12 of the probe 10 is shielded by the packaging bag 90. If the light projecting / receiving portion 12 of the probe 10 is shielded by the packaging bag 90, the light shielding cover 50 may be omitted.

  Next, the user connects the removed connector 11 to the connection portion 102 of the base unit 100. When the connector 11 is connected to the connection unit 102, the connector 11 is detected by the sensor 113, and a detection signal is output from the sensor 113 to the CPU 103. The connection of the connector 11 may not be detected by the sensor 113. In this case, the light source 111 is always in a light emitting state, and the CPU 103 recognizes the connection of the connector 11 from the change in the measurement result of the photometry unit 107. This is because when the connector 11 is connected to the connection unit 102, the measurement result of the photometry unit 107 changes.

  When the detection signal is input from the sensor 113 (step S1: Yes), the CPU 103 controls the light emission control unit 110 to cause the light source 111 to emit light (step S2). The excitation light emitted from the light source 111 is guided to its tip by the light projecting optical fiber 14. Excitation light emitted from the tip of the light projecting optical fiber 14 is projected onto the calibration target 30 by the lens 17. The excitation light is reflected by the calibration target 30, and the reflected light is collected by the lens 17 at the tip of the light receiving optical fiber 15. The reflected light received at the tip of the light receiving optical fiber 15 is guided to the photometry unit 107 by the light receiving optical fiber 15. Since the tip of the light projecting / receiving unit 12 is located in the immediate vicinity of the calibration target 30, excitation light and reflected light are hardly attenuated, and reflected light having high intensity enters the tip of the light receiving optical fiber 15. If the color of the calibration target 30 is black, the excitation light is hardly reflected by the calibration target 30. Therefore, the intensity of the excitation light incident on the tip of the light receiving optical fiber 15 is very low.

  After the light source 111 emits light, the CPU 103 causes the photometry unit 107 to perform photometry processing (step S3). Thereby, spectrum data and intensity data are measured by the photometry unit 107.

  Next, the CPU 103 performs calibration processing (step S4). Specifically, the CPU 103 determines whether or not the spectrum data and intensity data measured by the photometry unit 107 are included in an appropriate range. Further, the CPU 103 calculates a correction coefficient from both or one of spectrum data and intensity data measured by the photometry unit 107. If the color of the calibration target 30 is white, such calibration processing is intended to adjust the white balance and to adjust variations based on individual differences and combinations of the probe 10, the light source 111, and the photometry unit 107. And If the color of the calibration target 30 is black, the calibration process aims to grasp the intensity of stray light and the intensity of reflection noise derived from the lens 17 of the probe 10, the optical fibers 14, 15 and the like.

  Next, the CPU 103 records the determination result and the correction coefficient in step S4 in the RAM 104 (step S5). At this time, the CPU 103 associates the determination result and the correction coefficient with the previously recorded input identifier.

Next, the CPU 103 outputs a display command to the computer 114 via the interface 112 (step S6). Receiving the display command, the computer 114 causes the display monitor 116 to display a screen indicating that the calibration process has been completed. As a result, the user can easily understand the end of the calibration process.
Then, the CPU 103 ends the process with the determination result, the correction coefficient, and the input identifier stored in the RAM 104.

  Note that the CPU 103 may control the emission controller 110 to change the wavelength of the excitation light emitted from the light source 111 after the recording process in step S5 is completed and before the display process in step S6. Thereafter, the CPU 10 sequentially performs the photometry process, the calibration process, and the recording process described above, and then performs a display process (step S6).

  As described above, the user handles the diagnostic packaging 1 and the processing of the CPU 103 is performed, whereby calibration is performed. When the base unit 100 has a recording medium (for example, a nonvolatile memory, a magnetic disk drive, etc.) and the processing shown in FIG. 10 is completed, the CPU 103 records the input identifier, the determination result, and the correction coefficient recorded in the RAM 104. You may record on a medium. In this way, the input identifier, determination result, and correction coefficient for each probe 10 are accumulated in the recording medium, and it becomes easy to perform feedback such as lot management.

  When the user removes the connector 11 from the connecting portion 102 during or after the processing shown in FIG. 10, the sensor 113 detects that fact. Then, the CPU 103 deletes the input identifier, the determination result, and the correction coefficient stored in the RAM 104.

  After the calibration as described above is performed, the user removes the light shielding cover 50 without removing the connector 11 from the connection portion 102, and then the light projecting / receiving portion 12 of the probe 10 is taken out from the distal end housing portion 75. Then, if necessary, the light projecting / receiving portion 12 of the probe 10 is inserted into the lumen using the forceps channel of the endoscope. At that time, the illumination light source 109 may be turned on to illuminate the periphery of the light projecting / receiving unit 12.

  Thereafter, the light source 111 is turned on by the CPU 103. If it does so, excitation light will be projected on the measurement site | part of a biological tissue from the front-end | tip of the light projection light-receiving part 12 of the probe 10 with the optical fiber 14 for projection, and the lens 17. FIG. The measurement site of the living tissue emits fluorescence due to the excitation light, and the fluorescence is received at the tip of the light projecting / receiving unit 12 of the probe 10. The received fluorescence is transmitted to the photometry unit 107 through the light receiving optical fiber 15. The CPU 103 causes the photometric unit 107 to reflect the correction coefficient recorded in the RAM 104. Then, the intensity data and spectrum data of the fluorescence received by the photometry unit 107 are measured, and the intensity data and spectrum data are corrected with a correction coefficient. The intensity data and spectrum data corrected by the correction coefficient are signal processed by the signal processing unit 106 or transferred to the computer 114 by the CPU 103 and the interface 112. The computer 114 causes the display monitor 116 to display the corrected intensity data and spectrum data. Thereby, the measurement site | part of a biological tissue can be diagnosed.

  Since the probe 10 is disposable, after the diagnosis, the connector 11 is removed from the connection portion 102 and the probe 10 is discarded. The light shielding cover 50, the tray 70, the cover 80, and the packaging bag 90 are also discarded.

〔effect〕
According to the above embodiment, the following effects can be obtained.

(1) The probe 10 is housed in the probe housing recess 72 in a state where the front end surface of the light projecting / receiving unit 12 (particularly, the light projecting / receiving window 20) faces the calibration target 30. In particular, the distance between the tip surface of the light projecting / receiving unit 12 and the calibration target 30 is set appropriately. Therefore, it is not necessary to set the light projecting / receiving unit 12 of the probe 10 on an adjustment jig or the like during calibration. Furthermore, it is not necessary to prepare another large-scale adjustment jig. Therefore, it is convenient for the user.
(2) Since the front end surface of the light projecting / receiving unit 12 and the calibration target 30 face each other in advance and the periphery thereof is kept light-tight, the user can connect the connector 11 of the probe 10 to the connection unit 102 of the base unit 100. Just connect and calibration is done automatically. For this reason, it is not necessary to require the user to perform special work / load.
(3) Since the calibration target 30 and the light projecting / receiving unit 12 are shielded by the light shielding sheet 40 and the light shielding material 52, the calibration accuracy is high.
(4) Since the probe 10 and the calibration target 30 are a set, the new calibration target 30 can be used for calibration of the probe 10. Therefore, the calibration target 30 is not deteriorated or discolored, and accurate calibration can be performed.
(5) Since the diagnostic packaging 1 is simply configured, the cost of the diagnostic packaging 1 is low.
(6) The storage of the probe 10 is devised, so it is easy to use. Calibration can be performed without taking out the light projecting / receiving unit 12 of the probe 10.
(7) Since the probe 10 is disposable, it is convenient and hygienic.

<Second Embodiment>
FIG. 11 is an exploded perspective view of the distal end storage portion 75 and its surroundings in the second embodiment. FIG. 12 is a cross-sectional view of the tip storage portion 75. Parts corresponding to each other between the diagnostic package 1 in the first embodiment and the diagnostic package in the second embodiment are denoted by the same reference numerals. Hereinafter, the difference between the first embodiment and the second embodiment will be mainly described.

  In the first embodiment, the calibration target 30 is affixed to the abutting surface 76 of the tip storage portion 75, whereas in the second embodiment, the calibration target 30 is attached to the light shielding cover 50. It is attached.

  Here, a flap 54 is formed on the lower surface of the cover sheet 51, and the flap 54 hangs down from the cover sheet 51. The length of the flap 54 depending from the cover sheet 51 is longer than the length from the base of the stopper 53 to the protruding end of the stopper 53. The flap 54 and the stopper 53 face each other. The calibration target 30 is attached to the surface of the flap 54 that faces the stopper 53. Note that the surface of the flap 54 facing the stopper 53 may be colored so that the surface functions as the calibration target 30.

  In a state in which the front end storage portion 75 is covered with the light shielding cover 50, the flap 54 is inserted into the front end storage portion 75. The position where the flap 54 is inserted is between the abutting surface 76 and the stopper 77. The calibration target 30 faces away from the abutting surface 76 of the tip storage portion 75 and faces the tip surface of the light projecting / receiving portion 12 (particularly the light projecting / receiving window 20).

  Portions corresponding to each other between the diagnostic package 1 of the first embodiment and the diagnostic package of the second embodiment are provided in the same manner except for the above description.

  The method for handling the diagnostic package of the second embodiment is the same as that of the diagnostic package 1 of the first embodiment.

<Third embodiment>
FIG. 13 is a cross-sectional view of the tip storage portion 75 in the third embodiment. Parts corresponding to each other between the diagnostic package 1 in the first embodiment and the diagnostic package in the third embodiment are denoted by the same reference numerals. Hereinafter, the difference between the first embodiment and the third embodiment will be mainly described.

  The diagnostic package according to the third embodiment includes a second calibration target in addition to the probe 10, the calibration target 30, the light shielding sheet 40, the light shielding cover 50, the tray 70, the cover 80, the packaging bag 90, and the like. 31 and strip 32 are provided.

  The strip 32 penetrates the light shielding cover 50 vertically. Specifically, a slit 55 is formed in the cover sheet 51 of the light shielding cover 50, a cut 56 is formed in the light shielding material 52, the cut 55 is overlapped with the slit 55, and the strip 32 is passed through the slit 55 and the cut 56. Yes. The strip 32 is sandwiched between portions 57 and 58 on both sides of the notch 56 while being passed through the notch 56.

  As shown in FIG. 14, when the strip 32 comes out of the cut 56, the portions 57 and 58 on both sides of the cut 56 overlap with each other, and the cut 56 is closed by the portions 57 and 58 on both sides. The slit 55 is also closed by portions 57 and 58 on both sides of the cut 56.

  As shown in FIG. 13, the strip 32 vertically penetrates the wall (particularly the bottom) of the distal end storage portion 75. Specifically, a slit 78 is formed at the bottom of the tip storage portion 75, a notch 41 is also formed in the light shielding sheet 40, the notch 41 overlaps the slit 78, and the strip 32 is passed through the slit 78 and the notch 41. Yes. The strip 32 is sandwiched between portions 42 and 43 on both sides of the cut 41 while being passed through the cut 41. As shown in FIG. 14, when the strip 32 comes out of the notch 41, the portions 42 and 43 on both sides of the notch 41 overlap with each other and the notch 41 is blocked by the portions 42 and 43 on both sides. The slit 78 is also closed by the portions 42 and 43 on both sides of the cut 41.

  As shown in FIG. 13, the position where the slit 55 and the cut 56 are formed is between the stopper 53 and the calibration target 30. The position where the slit 78 and the notch 41 are formed is between the stopper 77 and the calibration target 30. The slit 55 and the slit 78 are opposed vertically.

  The strip 32 crosses the distal end storage portion 75 from the slit 55 side to the slit 78 side. The tip storage portion 75 is divided by the strip 32 into a region on the calibration target 30 side and a region on the stoppers 53 and 77 side.

  The strip 32 may not be passed through the notch 41 and the slit 78 but may be passed only through the slit 55 and the notch 56. In this case, the cuts 41 and the slits 78 may not be formed. Further, the strip 32 may not be passed through the notch 56 and the slit 55 but may be passed only through the slit 78 and the notch 41. In this case, the cut 56 and the slit 55 may not be formed. In any case, the strip 32 is inserted into the tip portion storage portion 75, and the tip portion storage portion 75 is divided by the strip 32 into a region on the calibration target 30 side and a region on the stoppers 53 and 77 side.

  The second calibration target 31 is disposed in the distal end housing portion 75 in a state of being disposed between the distal end surface of the light projecting / receiving unit 12 (particularly, the light projecting / receiving window 20) and the calibration target 30. .

  The second calibration target 31 is attached to the strip 32. Specifically, the second calibration target 31 is stuck to the surface on the stoppers 53 and 77 side of both surfaces of the strip 32. The second calibration target 31 faces the opposite side of the abutting surface 76 of the front end storage portion 75 and faces the front end surface of the light projecting / receiving portion 12 (particularly, the light projecting / receiving window 20).

  As shown in FIG. 14, when the strip 32 is pulled out from the slits 55 and 78, the second calibration target 31 is taken out of the tip portion storage portion 75. Therefore, there is nothing to block between the front end surface of the light projecting and receiving unit 12 and the calibration target 30.

  It is preferable that the color of the calibration target 30 and the color of the second calibration target 31 are different. Specifically, the color of the calibration target 30 is black, and the color of the second calibration target 31 is a color other than black (for example, white, red, green, blue, yellow, magenta, or cyan). Among these, it is preferable that the color of the second calibration target 31 is white. The second calibration target 31 may be a uniform single color, or may be an array of various colors such as a so-called color chart.

  The second calibration target 31 is, for example, a standard color chart such as Munsell color, a standard color plate, a standard fluorescent sample, or a Raman standard sample. The strip 32 may be colored so that the strip 32 functions as the second calibration target 31.

  Portions corresponding to each other between the diagnostic package 1 of the first embodiment and the diagnostic package of the third embodiment are provided in the same manner except for the above description.

The method for handling a diagnostic package and the operation of the base unit 100 according to the third embodiment will be described.
FIG. 15 is a flowchart showing the flow of processing performed by the CPU 103 of the base unit 100 according to the program.

  CPU 103 waits until a detection signal is input from sensor 113 (step S11: No).

  On the other hand, the user removes the probe 10, the light shielding cover 50 and the cover 80 together with the tray 70 from the packaging bag 90 and removes the cover 80 from the tray 70. Then, the user inputs the same value as the identifier 26 attached to the probe 10 with the input device 115. Then, the CPU 103 records the input identifier transferred from the computer 114 to the CPU 103 in the RAM 104.

  Next, the user removes the connector 11 of the probe 10 from the connector storage portion 73 and connects the connector 11 to the connection portion 102 of the base unit 100. Then, the connector 11 is detected by the sensor 113 and a detection signal is output from the sensor 113 to the CPU 103. When the detection signal is input from the sensor 113 (step S11: Yes), the CPU 103 controls the light emission control unit 110 to cause the light source 111 to emit light (step S12).

  The excitation light emitted from the light source 111 is projected onto the second calibration target 31 by the light projecting optical fiber 14 and the lens 17. The excitation light is reflected by the second calibration target 31. The reflected light is collected at the tip of the light receiving optical fiber 15 by the lens 17 and guided to the photometry unit 107 by the light receiving optical fiber 15. Since the tip of the light projecting / receiving unit 12 is located in the immediate vicinity of the second calibration target 31, excitation light and reflected light are hardly attenuated, and high intensity reflected light is incident on the tip of the light receiving optical fiber 15. To do.

  After the light source 111 emits light, the CPU 103 causes the photometry unit 107 to perform photometry processing (step S13). The photometric unit 107 measures spectral data and intensity data.

  Next, the CPU 0103 determines whether or not the spectrum data and intensity data measured by the photometry unit 107 are included in an appropriate range, and corrects from both or one of the spectrum data and intensity data measured by the photometry unit 107. A coefficient is calculated (step S14). If the color of the second calibration target 31 is white, such calibration processing is intended to adjust the white balance and to adjust variations based on individual differences and combinations of the probe 10, the light source 111, and the photometry unit 107. With the goal.

  Next, the CPU 103 records the determination result in step S4 and the correction coefficient in the RAM 104 in association with the input identifier (step S15).

  Next, the CPU 103 outputs a display command to the computer 114 via the interface 112 (step S16). Upon receiving the display command, the computer 114 causes the display monitor 116 to display a screen that prompts the user to pull out the strip 32. As a result, the next handling operation can be easily understood by the user.

  Next, the CPU 103 waits until the measurement result of the photometry unit 107 changes (step S17: No).

  On the other hand, the user pulls out the strip 32 from the slits 55 and 78. When the strip 32 is pulled out, the second calibration target 31 comes off from the front of the light projecting / receiving unit 12 of the probe 10, and the calibration target 30 faces the tip of the light projecting / receiving unit 12 of the probe 10. If the color of the calibration target 30 is black, the excitation light is hardly reflected by the calibration target 30. Even if the excitation light is reflected by the calibration target 30, the distance from the tip of the light projecting and receiving unit 12 to the calibration target 30 is large, so that the reflected light is likely to attenuate. Therefore, the intensity of the reflected excitation light received at the tip of the light projecting / receiving unit 12 of the probe 10 is also very low.

  The measurement result of the photometric unit 107 changes when the target directly facing the tip of the light projecting / receiving unit 12 of the probe 10 is changed from the second calibration target 31 to the calibration target 30. When the CPU 103 recognizes a change in the measurement result of the photometry unit 107 (step S17: Yes), the CPU 103 causes the photometry unit 107 to perform photometry processing (step S18). Thereby, spectrum data and intensity data are measured by the photometry unit 107.

  Next, the CPU 0103 determines whether or not the spectrum data and intensity data measured by the photometry unit 107 are included in an appropriate range, and corrects from both or one of the spectrum data and intensity data measured by the photometry unit 107. A coefficient is calculated (step S19). Since the intensity of the reflected excitation light received at the tip of the light projecting / receiving unit 12 of the probe 10 is very low, the calibration process in step S19 is performed with the intensity of stray light derived from the lens 17 of the probe 10, the optical fibers 14, 15 and the like. It aims at grasping the intensity of reflection noise.

  Next, the CPU 103 records the determination result in step S9 and the correction coefficient in the RAM 104 in association with the input identifier (step S20).

Next, the CPU 103 outputs a display command to the computer 114 via the interface 112 (step S21). Receiving the display command, the computer 114 causes the display monitor 116 to display a screen indicating that the calibration process has been completed. As a result, the user can easily understand the end of the calibration process.
Then, the CPU 103 ends the process with the determination result, the correction coefficient, and the input identifier stored in the RMA 104.

  Note that the CPU 103 may control the light emission control unit 110 to change the wavelength of the excitation light emitted from the light source 111 after the recording process in step S15 and before the display process in step S16. Thereafter, the CPU 10 sequentially performs the photometry process, the calibration process, and the recording process described above, and then performs a display process (step S16). The same applies to the case after the end of the recording process in step S20 and before the display process in step S21.

  As in the case of the first embodiment, when the processing shown in FIG. 15 is completed, the CPU 103 stores the input identifier, determination result, and correction coefficient recorded in the RAM 104 on a recording medium (nonvolatile memory, magnetic disk, etc.). It may be recorded. Further, when the user removes the connector 11 from the connection unit 102 during or after the process illustrated in FIG. 15, the CPU 103 may delete the input identifier, the determination result, and the correction coefficient stored in the RAM 104.

  After the calibration as described above, as in the case of the first embodiment, the user takes out the probe 10 from the tray 70, inserts the light projecting / receiving unit 12 of the probe 10 into the lumen, The probe 10 is used to diagnose the measurement site of the living tissue.

  According to the third embodiment described above, the following effects are also produced in addition to the effects produced by the first embodiment.

(1) Since the calibration targets 30 and 31 are disposed in the tip storage part 75, the calibration can be performed twice.
(2) Since the light projecting / receiving unit 12 and the second calibration target 31 are preliminarily placed in the tip storage unit 75, the light projecting / receiving unit 12 of the probe 10 is adjusted to the adjustment jig at the first calibration. There is no need to set it to the user, and it is convenient for the user.
(3) Since the front end surface of the light projecting / receiving unit 12 and the periphery of the second calibration target 31 are kept light-tight in advance, the accuracy of the first calibration is high, and the user has a special work and burden. No need to request.
(4) The second calibration can be performed by simply pulling out the strip 32.
(5) Even when the strip 32 is pulled out, the front end surface of the light projecting / receiving unit 12 and the periphery of the calibration target 30 are kept light tight in advance. Therefore, the second calibration is also highly accurate.
(6) Since the handling procedure is displayed on the display monitor 116, the calibration order can be reliably performed without making a mistake.

<Fourth embodiment>
FIG. 16 is a cross-sectional view of the distal end storage portion 75 in the fourth embodiment. Parts corresponding to each other between the diagnostic package in the fourth embodiment and the diagnostic package in the third embodiment are denoted by the same reference numerals. In addition, portions corresponding to each other between the diagnostic package of the fourth embodiment and the diagnostic package of the third embodiment are provided in the same manner except as described below.

  In the fourth embodiment, the strip 32 penetrates the bottom of the tip portion storage section 75, the light shielding sheet 40, the cover sheet 51, and the light shielding material 52, and the second calibration target 31 is adhered to the strip 32. Since this point is the same as that of the third embodiment, detailed description thereof is omitted.

  In the fourth embodiment, a flap 54 is formed on the lower surface of the cover sheet 51, and the calibration target 30 is adhered to the flap 54. Since this point is the same as in the second embodiment, detailed description thereof is omitted.

  The method of handling the diagnostic package of the fourth embodiment is the same as that of the diagnostic package of the third embodiment.

DESCRIPTION OF SYMBOLS 1 Package for diagnosis 10 Probe 11 Connector 12 Light-emission light-receiving part 13 Cable main-body part 13
30 calibration target 31 second calibration target 32 strip 40 light shielding sheet 50 light shielding cover 51 cover sheet 52 light shielding material 53 stopper 54 flap 70 tray 71 tray body 72 probe housing recess 73 connector housing portion 74 cable housing portion 75 tip portion housing portion 77 Stopper 90 Packaging bag

Claims (14)

A tray,
A probe housed in the tray for transmitting, projecting and receiving light;
A calibration target that is irradiated with light emitted from the probe during calibration of the probe;
A packaging bag enclosing the probe, the calibration target, and the tray;
The tray has a tray main body, a ring-shaped cable storage portion recessed in the upper surface of the tray main body, and a recess formed in the upper surface of the tray main body, connected to the cable storage portion, and the cable from the cable storage portion to the cable A connector storage portion extending in a tangential direction of the storage portion; a tip storage portion recessed in the upper surface of the tray main body, connected to the cable storage portion, and extending from the cable storage portion in a tangential direction of the cable storage portion; Have
The probe is connected to a cable main body for transmitting light, a connector for inputting / outputting light, and connected to a distal end of the cable main body for light projection and light reception. A light receiving and receiving unit,
The light projecting / receiving unit is stored in the tip storage unit, the cable body unit is stored in the cable storage unit, and the connector is stored in a connector storage unit;
A diagnostic package, wherein the calibration target is disposed in the tip storage portion so as to face the tip of the light projecting / receiving portion.   The diagnostic packaging according to claim 1, further comprising a light-shielding material fitted into the tip portion storage portion from above the light projecting and receiving portion.   The diagnostic packaging according to claim 1, further comprising a light shielding sheet that is attached to an inner wall of the tip storage portion and encloses the light projecting and receiving portion.   2. The apparatus further comprises a second calibration target disposed in the distal end storage portion so as to face the distal end of the light projecting / receiving unit, and disposed between the calibration target and the light projecting / receiving unit. 4. The diagnostic packaging according to any one of items 1 to 3. A strip that penetrates the light shielding material from the tip portion storage portion to the outside of the tip portion storage portion;
A second calibration target that is affixed to the strip and disposed in the distal end housing portion so as to face the distal end of the light projecting / receiving unit, and disposed between the calibration target and the light projecting / receiving unit. The diagnostic packaging according to claim 2, further comprising: A strip penetrating the light shielding sheet and the wall of the tip portion storage portion from the tip portion storage portion to the outside of the tip portion storage portion;
A second calibration target that is affixed to the strip and disposed in the distal end housing portion so as to face the distal end of the light projecting / receiving unit, and disposed between the calibration target and the light projecting / receiving unit. The diagnostic packaging according to claim 3, further comprising:   The diagnostic packaging according to any one of claims 4 to 6, wherein the color of the calibration target is different from the color of the second calibration target.   The diagnostic packaging according to any one of claims 4 to 6, wherein the color of the calibration target is black and the color of the second calibration target is white.   The diagnostic packaging according to any one of claims 1 to 8, wherein the calibration target is attached to an inner wall of the tip storage unit. A cover sheet that covers the tip storage part from above the light projecting and receiving part;
A flap that hangs between the calibration target and the light projecting / receiving unit in the tip portion storage unit from the cover sheet,
The diagnostic packaging according to any one of claims 1 to 8, wherein the calibration target is attached to the flap. A cover sheet that covers the tip storage part from above the light projecting and receiving part;
A flap that hangs between the calibration target and the light projecting / receiving unit in the tip portion storage unit from the cover sheet,
The shading material is adhered to the cover sheet;
The diagnostic packaging according to claim 2 or 5, wherein the calibration target is attached to the flap. A cover sheet that covers the tip storage part from above the light projecting and receiving part;
A flap that hangs between the calibration target and the light projecting / receiving unit in the tip portion storage unit from the cover sheet,
The strip penetrates the cover sheet;
The shading material is adhered to the cover sheet;
The diagnostic packaging according to claim 5, wherein the calibration target is attached to the flap. The tray further has a stopper projecting from the inner wall of the tip storage section;
The tip of the light projecting / receiving portion abuts on the stopper,
The diagnostic packaging according to any one of claims 1 to 12, wherein the calibration target is disposed in the tip portion storage portion on the opposite side of the light projecting / receiving portion with respect to the stopper. Further provided with a stopper protruding from the lower surface of the cover sheet and projecting into the tip storage section,
The tip of the light projecting / receiving portion abuts on the stopper,
The diagnostic packaging according to any one of claims 10 to 12, wherein the calibration target is disposed in the tip portion storage portion on the opposite side of the light projecting / receiving portion with respect to the stopper.

Images