JP2012132694A - Agglutination information input processing system and method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an agglutination information input processing system with simple system configuration, at low cost and with further improved work efficiency.SOLUTION: An agglutination information input processing system includes: inspection device identification member 7; identification information reading means 3 for reading inspection device identification information 8; display means 4 on which an input indicator 9 and a digitizer are loaded and a display screen 10 is arranged in parallel; positioning means 5 for arrangeably positioning an inspection device 2 in a predetermined area 11 on the display screen; and internal control means 6, and is constituted so that the internal control means displays an image picture 12 of each well W of an inspection device relevant to the inspection device identification information read by the identification information reading means on a display screen corresponding to the predetermined area, performs pattern display of a visual inspection determination result of agglutination of each well corresponding to an image picture at a lower part of the inspection device by detecting a contact state of the input indicator to an upper part of each well of the inspection device arranged in the predetermined area to record the visual inspection determination result.

Description

  The present invention relates to an agglutination reaction information input processing system and method, and more specifically, agglutination reaction information obtained by visually determining an agglutination reaction in a test device having a plurality of wells into which a specimen and a reagent are dispensed. The present invention relates to an aggregating reaction information input processing system and method for input processing.

  In medical practice, a test device called a microplate is used to perform an agglutination test of a specimen such as blood or body fluid of a subject. The microplate is formed of, for example, a light-transmitting plastic material, and includes a plurality of wells into which a specimen and a reagent are dispensed. One microplate generally has, for example, a total of 96 wells arranged in an 8 × 12 array.

A conventional agglutination reaction test using this microplate will be briefly described below.
First, a specimen and a reagent are dispensed into each well of the microplate. Then, after a predetermined time has elapsed from this dispensing, the inspector visually determines the agglutination reaction that has occurred in each well. In this visual judgment, the inspector memorizes which well position is in what aggregation state, and records the aggregation reaction information on a paper medium such as a worksheet or on a terminal such as a personal computer. Enter and process.
However, in this method, the inspector must memorize well positions and their aggregation states one by one in the head, so that the operation is extremely inefficient and places a heavy burden on the inspector. It was. Also, in this work, especially when the examiner makes a mistake in the well position (for example, when the state of aggregation at one well position is mistaken for the state of aggregation at another well position), an error in recording on the paper medium or terminal There was also a problem that an input error occurred and this led to a serious medical test error.

  By the way, in order to improve the inefficiency of the above work and reduce the burden on the examiner, an agglutination reaction information input processing system (data collection system) including a touch type microplate reader has been proposed (for example, non-patent document). 1).

FIG. 9 is a perspective view schematically showing an agglutination reaction information input processing system inferred from the content of “touch type microplate reader KI-100” on the homepage of Non-Patent Document 1. As shown in FIG. 9, the agglutination reaction information input processing system 100 includes a microplate reader 101, a microplate 102, an input indicator 103 such as a touch pen, and a host computer 104.
The microplate reader 101 includes an accommodating portion 101a formed inside the microplate reader body, a glass touch panel portion 101b, a display portion 101c, and an operation key portion 101d provided on the upper surface of the microplate reader body. Have. The accommodating portion 101a can accommodate the microplate 102 inserted from the insertion opening formed on one side surface of the microplate reader main body. The glass touch panel portion 101b is a known touch panel made of transparent and flat glass. The display unit 101c includes a plurality of LEDs. The LEDs of the display unit 101c are arranged adjacent to the panel unit 101b in an arrangement corresponding to the arrangement of the wells W of the microplate 102.

The agglutination reaction information input processing method using the agglutination reaction information input processing system 100 will be briefly described below within a range that can be inferred from the contents disclosed in Non-Patent Document 1 by the applicant.
First, a specimen and a reagent are dispensed into each well W of the microplate 102, and the microplate 102 in which the agglutination reaction has occurred is inserted into the insertion opening and set in the accommodating portion 101a. Thereafter, the examiner visually determines the aggregation state of each well position of the microplate 102 set in the storage unit 101a from the upper side of the glass touch panel unit 101b. In this visual determination, the inspector touches the upper glass touch panel portion 101b corresponding to the well position to be determined with the input indicator 103. After this touch, the LED of the display unit 101c corresponding to the well position to be determined is displayed, for example, in red (see the shaded area in FIG. 9). Thereby, the inspector can confirm that there is no problem in the well position to be determined by himself / herself. Thereafter, the examiner inputs necessary information regarding the aggregation state of the well position to be determined by performing an input operation on the operation key unit 101d. Then, by further operating the operation key unit 101d, the agglutination reaction information including each well position to be determined and its agglutination state is sent from the microplate reader 101 to the host computer 104 for processing.

Internet URL <http://www.koden.jp/product_04.html>, homepage of Koden Kogyo Co., Ltd., search on September 2, 2010

However, in the agglutination reaction information input processing system 100 of Non-Patent Document 1, although the inefficiency of the above work and the burden on the inspector are slightly improved and reduced, the following problems still exist.
(1) First, the agglutination reaction information input processing system 100 requires at least two advanced information processing apparatuses such as a microplate reader 101 and a host computer 104. Therefore, the system configuration is complicated and cost reduction is difficult.
(2) Secondly, in this agglutination reaction information input processing system 100, after touching the glass touch panel 101b corresponding to the well position to be determined with the input indicator 103, whether or not the well position has been correctly selected, It is still necessary to check the position of the corresponding LED on the display unit 101c adjacent to the glass touch panel unit 101b. Therefore, in this agglutination reaction information input processing system 100, it is difficult to say that the work efficiency is greatly improved.

  Therefore, the present invention has been made in view of such circumstances, and provides an agglutination reaction information input processing system that has a simple and low-cost system configuration and further improves work efficiency.

In order to solve the above-described problems, the first invention is obtained by visually determining an agglutination reaction occurring in each well in at least one test device having a plurality of wells into which a specimen and a reagent are dispensed. An agglutination reaction information input processing system for performing input processing on the agglutination reaction information, an inspection device identification member attached to each of the inspection devices and having inspection device identification information for each of the inspection devices, and the inspection device An identification information reading means for reading the inspection device identification information of the identification member, an input indicator and a digitizer, and a display means in which a display screen capable of performing an input instruction operation by the input indicator is horizontally arranged on the display screen Positioning means for positioning the inspection device in a predetermined area, the identification information reading means, and an input Internal control means for controlling the display means based on the output of the indicator and digitizer, the internal control means receiving the inspection device identification information read by the identification information reading means, An image image display unit for displaying an image image of each well of the inspection device related to the inspection device identification information on the display screen corresponding to the predetermined region, and each after the aggregation reaction of the inspection device arranged in the predetermined region By detecting the contact state of the input indicator with respect to the upper part of the well, the agglutination reaction result display unit that pattern-displays the visual determination result of the agglutination reaction of each corresponding well in the image image of the lower part of the inspection device; A determination result recording unit that records the visual determination result displayed in a pattern by the agglutination reaction result display unit; It is obtained by the agglutination information input processing system, which comprises.
According to the first aspect of the invention, the internal control means controls the display means based on the outputs of the identification information reading means, the input indicator and the digitizer, so that the agglutination reaction information of the inspection device can be easily input. It is configured. Therefore, two advanced information processing apparatuses such as a microplate reader and a host computer as in the prior art are not required. Therefore, the system configuration can be made simpler than the conventional system, and the cost can be reduced.
According to the first aspect, the inspection device is positioned and arranged in a predetermined area on the display screen on which the image of each well of the inspection device is displayed, and the input indicator is provided above each well of the inspection device. By making the contact, the visual result of the aggregation reaction of each corresponding well in the image image of the lower part of the inspection device is configured to be displayed in a pattern. Therefore, since the relationship between each well position and its aggregation state can be accurately visually confirmed from the upper side of the inspection device, it is possible to further improve the work efficiency of inputting the obtained aggregation reaction information.

In the second invention, the agglutination reaction information obtained by visually judging the agglutination reaction occurring in each well in at least one test device having a plurality of wells into which the specimen and the reagent are dispensed is input. An agglutination reaction information input processing system for processing, wherein at least one inspection device corresponding to each inspection item is received by receiving inspection request information including information on at least one subject and inspection items. An inspection request information receiving means for creating inspection device dispensing information including information relating to an injection sequence, a well position and an inspected person, and registering it in a database; and an inspection device for each inspection device attached to each of the inspection devices Read the inspection device identification member having identification information and the inspection device identification information of the inspection device identification member. Identification information reading means, and inspection device identification information for each inspection device by receiving each inspection device identification information read by the identification information reading means before the visual inspection of the agglutination reaction in each inspection device, Inspection device linking information created by linking inspection device dispensing information is created, and the inspection device reservation setting means, input indicator, and digitizer that are registered in the database are installed, and input instructions can be operated by the input indicator. Display means in which a display screen is horizontally arranged, positioning means for positioning the inspection device in a predetermined area on the display screen, output of the identification information reading means, input indicator and digitizer On the basis of the internal control means for controlling the display means, the internal control means After the inspection device linking information is created by the inspection device reservation setting means, the inspection device linking information stored in the database is retrieved by receiving the inspection device identification information read by the identification information reading means. When there is inspection device dispensing information associated with the inspection device identification information, an image image display unit that displays an image of each well of the inspection device on the display screen corresponding to the predetermined area; By detecting the contact state of the input indicator with respect to the upper part of each well after the aggregation reaction of the inspection device arranged in the predetermined region, the aggregation reaction of each corresponding well in the image image of the lower part of the inspection device Agglutination reaction result display section for displaying the visual judgment result of the pattern, and the agglutination reaction result table And a determination result recording unit that records a visual determination result displayed in a pattern by the display unit.
According to the second invention, the inspection device identification information for each inspection device read by the identification information reading means before the visual inspection of the aggregation reaction in each inspection device, and the inspection device dispensing created by the inspection request information receiving means. The information is associated with the inspection device reservation setting means and is registered in the database as inspection device association information. Therefore, even when the agglutination reaction in a plurality of inspection devices is visually inspected, the consistency between the inspection device identification information of each inspection device and the inspection device dispensing information can be maintained.

In the third invention, in the first invention or the second invention, the aggregation reaction result display unit determines whether the inspection device is arranged in a correct direction in the predetermined region, and the inspection device is in a correct direction. In the case where it is not arranged, the agglutination reaction information input processing system is configured so that the input indicator cannot be used to input a visual determination result.
According to the third aspect of the present invention, it is possible to prevent an erroneous input of the visual determination result due to the inspection device being arranged in the wrong direction in the predetermined region.

According to a fourth aspect of the present invention, in any one of the first to third aspects, the image display unit displays a mark for arranging the inspection device in the correct direction in the predetermined area on the display screen. The agglutination reaction information input processing system is configured.
According to the fourth aspect of the invention, the inspection device can be arranged in the correct orientation simply by following the mark on the display screen.

The fifth invention is the aggregation reaction information input processing system according to any one of the first to fourth inventions, wherein the positioning means is formed of a transparent flat plate member having an accommodating portion capable of accommodating the inspection device in the predetermined region. It is what.
According to the fifth aspect of the present invention, the inspection device can be accurately set in the predetermined region simply by putting it into the accommodating portion of the flat plate member.

In a sixth aspect of the present invention, in any one of the first to fifth aspects, the inspection device includes a lid member that is attached to the inspection device body and has a plurality of recesses that cover each well from above, and the aggregation The reaction result display unit detects the contact state of the input indicator with respect to the recess of each well after the agglutination reaction of the inspection device arranged in the predetermined region. The agglutination reaction information input processing system displays a pattern of the visual determination result of the agglutination reaction of each well.
According to the sixth aspect, contamination (foreign matter) into each well is suppressed by the lid member. In addition, since the concave portion of the lid member stably receives the contact portion of the input indicator, the operation of contacting the input indicator with respect to the upper portion of each well of the inspection device can be performed stably.

In the seventh invention, the agglutination reaction information obtained by visually judging the agglutination reaction occurring in each well in at least one test device having a plurality of wells into which the specimen and the reagent are dispensed is input. A method of processing, comprising: (a) providing a display means equipped with an input indicator and a digitizer, having a display screen capable of performing an input instruction operation by the input indicator, and arranging the display screen horizontally; (B) a step of reading the inspection device identification information of the inspection device identification member attached to each inspection device by an identification information reading means; and (c) the read inspection device identification after the execution of the step (b). After an image of each well of the inspection device related to information is displayed on the display screen, a predetermined area on the display screen including the image image is displayed. And (d) bringing the input indicator into contact with the upper part of each well after the agglutination reaction of the inspection device arranged in the predetermined region. The method is characterized in that, after the execution of step (d), the visual determination result of the agglutination reaction of each corresponding well in the image image below the inspection device arranged in the predetermined region is displayed in a pattern. It is.
According to the seventh aspect, the inspection device is positioned and arranged in a predetermined area on the display screen on which the image of each well of the inspection device is displayed, and the input indicator is brought into contact with the upper portion of each well of the inspection device. Thus, the visual result of the aggregation reaction of each corresponding well in the image image of the lower part of the inspection device is configured to be displayed in a pattern. Therefore, since the relationship between each well position and its aggregation state can be accurately visually confirmed from the upper side of the inspection device, it is possible to further improve the work efficiency of inputting the obtained aggregation reaction information.

In the eighth invention, the agglutination reaction information obtained by visually determining the agglutination reaction occurring in each well in at least one test device having a plurality of wells into which the specimen and the reagent are dispensed is input. A method of processing, comprising: (a) receiving inspection request information including information on at least one subject and inspection items, and at least a dispensing sequence and a well position for each inspection device corresponding to each inspection item And a step of creating inspection device dispensing information including information on the person to be inspected and registering it in the database, and (b) an inspection device attached to each inspection device before visual inspection of the agglutination reaction in each inspection device The inspection device identification information of the identification member is read by the identification information reading means, and each of the inspection device identification information and the inspection device Creating inspection device association information associated with the order information and registering it in the database, and setting the inspection device reservation; and (c) equipped with an input indicator and digitizer and input by the input indicator Preparing display means having a display screen that can be instructed and arranging the display screen horizontally; (d) inspection device identification information of an inspection device identification member attached to the inspection device to be visually inspected; And (e) after executing step (d), an image of each well of the inspection device related to the read inspection device identification information is displayed on the display screen. And positioning and arranging the inspection device in a predetermined area on the display screen including the image (F) bringing the input indicator into contact with the upper part of each well after the agglutination reaction of the inspection device arranged in the predetermined region, and after executing the step (f), The method is characterized in that the visual determination result of the agglutination reaction of each corresponding well in the image image of the lower part of the inspection device arranged in the region is displayed in a pattern.
According to the eighth aspect of the invention, inspection device identification information for each inspection device read by the identification information reading means before visual inspection of the agglutination reaction in each inspection device, and inspection device dispensing created by receiving inspection request information The information is associated with the inspection device reservation setting means and is registered in the database as inspection device association information. Therefore, even when the agglutination reaction in a plurality of inspection devices is visually inspected, the consistency between the inspection device identification information of each inspection device and the inspection device dispensing information can be maintained.

  According to the present invention, it is possible to provide an agglutination reaction information input processing system that has a simple system configuration and is low in cost and further improved in work efficiency.

(A) is a block diagram of the agglutination reaction information input processing system by 1st Example of this invention, (B) is a display screen displayed on a display means in the agglutination reaction information input processing system of (A). It is a figure which shows an example. (A) is a perspective view which shows the state which has arrange | positioned the test | inspection device of FIG. 1 (A) in the predetermined area | region, (B) is a fragmentary sectional view along the XX 'line of (A). (C) is a figure which shows an example of the display screen displayed on a display means in the aggregation reaction information input processing system of (A). It is a flowchart figure explaining the aggregation reaction information input processing method by 1st Example of this invention. (A) is a block diagram of the agglutination reaction information input processing system according to the second embodiment of the present invention, and (B) explains the operation of the inspection request information receiving means in the agglutination reaction information input processing system of (A). It is a figure to do. (A) is a partial block diagram of the aggregation reaction information input processing system according to the second embodiment of the present invention, and (B) is displayed on the display means in the aggregation reaction information input processing system of (A). It is a figure which shows an example of a display screen. (A) is a perspective view which shows the state which has arrange | positioned the test | inspection device of FIG. 5 (A) in the predetermined area | region, (B) is a fragmentary sectional view along the XX 'line of (A). (C) is a figure which shows an example of the display screen displayed on a display means in the aggregation reaction information input processing system of (A). It is a flowchart figure explaining the aggregation reaction information input processing method by 2nd Example of this invention. (A) is a perspective view which shows the test | inspection device which attached the cover member, (B) is a partial sectional view along the X-X 'line of (A). It is the perspective view which showed schematically the conventional agglutination reaction information input processing system.

  Next, preferred embodiments of the aggregation reaction information input processing system and method according to the present invention will be described with reference to the drawings.

[First embodiment]
Hereinafter, (1-1) the configuration of the agglutination reaction information input processing system of the first embodiment, (1-2) the agglutination reaction information input processing method, and (1-3) the effect will be described.

(1-1) Configuration of Aggregation Reaction Information Input Processing System FIG. 1 (A) is a configuration diagram of an aggregation reaction information input processing system according to the first embodiment of the present invention, and (B) is an aggregation of (A). It is a figure which shows an example of the display screen displayed on a display means in a reaction information input processing system.
As shown in FIG. 1, the agglutination reaction information input processing system 1 includes an inspection device 2, identification information reading means 3, display means 4, positioning means (not shown), and internal control means 6. .

The inspection device 2 includes a plurality of wells W into which a specimen and a reagent are dispensed, and is formed of a known microplate formed from a plastic material having optical transparency. In this embodiment, the inspection device 2 includes a total of 96 wells in a horizontal 8 × longitudinal arrangement (well positions <A-1> to <H-12>).
Further, an inspection device identification member 7 having inspection device identification information 8 of the inspection device 2 is attached to the inspection device 2. In this embodiment, the inspection device identification information 8 is written on the surface of the inspection device identification member 7 in a barcode format.

  The identification information reading means 3 reads the inspection device identification information 8 of the inspection device identification member 7, and is composed of a known barcode reader in this embodiment.

  The display means 4 is equipped with a known input indicator 9 and a digitizer (not shown), and has a display screen 10 on which an input instruction can be operated by the input indicator 9. The display screen 10 is arranged horizontally. As the display means 4, a general-purpose display device such as a liquid crystal display equipped with a digitizer or a plasma display is used.

  The positioning means is for positioning the inspection device 2 in a predetermined area (area corresponding to the size of the inspection device 2) 11 on the display screen 10 so that the inspection device 2 can be arranged.

The internal control means 6 controls the display means 4 based on the output of the identification information reading means 3, the input indicator 9, and the digitizer. The internal control means 6 includes an image image display unit 6a, an aggregation reaction result display unit 6b, and a determination result recording unit 6c.
The image image display unit 6 a receives the inspection device identification information 8 read by the identification information reading unit 3, and thereby, the image image 12 of each well W of the inspection device 2 related to the inspection device identification information 8 is predetermined. This is displayed on the display screen 10 corresponding to the area 11.
The agglutination reaction result display unit 6b detects the contact state of the input indicator 9 with respect to the upper part of each well W after the agglutination reaction of the inspection device 2 arranged in the predetermined region 11, thereby lowering the lower part of the inspection device 2. The visual determination result of the aggregation reaction of each corresponding well W in the image image 12 is displayed in a pattern with a color or a pattern.
The pattern display process is preferably executed by a known coordinate sensing process of the digitizer and the input indicator 9.
The determination result recording unit 6c records the visual determination result displayed as a pattern by the aggregation reaction result display unit 6b on a recording medium such as a database.

(1-2) Aggregation Reaction Information Input Processing Method By operating the aggregation reaction information input processing system 1 having the above configuration, the aggregation reaction information input processing method according to the first embodiment of the present invention can be implemented.
2A is a perspective view showing a state in which the inspection device of FIG. 1A is arranged in a predetermined region, and FIG. 2B is a partial cross-sectional view taken along line XX ′ in FIG. (C) is a figure which shows an example of the display screen displayed on a display means in the aggregation reaction information input processing system of (A). FIG. 3 is a flowchart for explaining the aggregation reaction information input processing method.

  First, as shown in FIGS. 1A and 3, the display unit 4 is prepared, and the display screen 10 is horizontally arranged (see step S1 in FIG. 3).

  Next, the inspection device identification information 8 of the inspection device identification member 7 attached to the inspection device 2 is read by the identification information reading means 3 (see step S2 in FIG. 3). After executing step S2, the image display unit 6a receives the inspection device identification information 8 from the identification information reading unit 3. As a result, as shown in FIGS. 1A and 1B, the image image 12 of each well W of the inspection device 2 related to the inspection device identification information 8 read by the identification information reading means 3 is displayed on the display screen 10. Is done.

  Thereafter, the inspection device 2 is positioned and arranged in a predetermined area 11 on the display screen 10 including the image 12 (see step S3 in FIG. 3).

Next, as shown in FIGS. 2A, 2 </ b> B, and 3, each well W (for example, well position <H-6> in FIG. 2) after the aggregation reaction of the test device 2 arranged in the predetermined region 11. The input indicator 9 is brought into contact with the upper part (see step S4 in FIG. 3).
Then, the aggregation state (weak positive, positive, retest, hold, negative) of the visual judgment screen 13 displayed adjacent to the image 12 is selected by the input indicator 9 (for example, well position <H-6 in FIG. 2). In the case of>, weak positive is selected as the aggregation state). At this time, the agglutination reaction result display unit 6b detects the contact state of the input indicator 9 with respect to the upper portion of the well W, so that the corresponding well W in the image image 12 below the inspection device 2 arranged in the predetermined region 11 is detected. The visual determination result of the agglutination reaction is displayed in a pattern with a color or pattern (for example, in the case of well position <H-6> in FIG. 2, a hatched pattern is displayed).
Further, the end command displayed on the lower side of the visual judgment screen 13 is selected by the input indicator 9. At this time, the determination result recording unit 6c records the pattern-displayed visual determination result on a recording medium such as a database.

(1-3) Effect According to the invention of the first embodiment, the internal control means 6 controls the display means 4 based on the output of the identification information reading means 3, the input indicator 9, and the digitizer, whereby the inspection device 2 The aggregating reaction information is easily input so as to be input. Therefore, two advanced information processing apparatuses such as a microplate reader and a host computer as in the prior art are not required. For this reason, the system configuration can be made simpler than the conventional one, and the cost can be reduced.
Further, according to the invention of the first embodiment, the inspection device 2 is positioned and arranged in the predetermined area 11 on the display screen 10 on which the image 12 of each well W of the inspection device 2 is displayed. By bringing the input indicator 9 into contact with the upper part of each well W, the visual result of the agglutination reaction of each corresponding well W in the image 12 at the lower part of the inspection device 2 is configured to be displayed in a pattern. Therefore, since the relationship between each well position and its aggregation state can be accurately visually confirmed from the upper side of the inspection device 2, the work efficiency of inputting the obtained aggregation reaction information can be further improved.

[Second Embodiment]
Hereinafter, (2-1) the configuration of the aggregation reaction information input processing system of the second embodiment, (2-2) the aggregation reaction information input processing method, and (2-3) the effect will be described.
The agglutination reaction information input processing system of the second embodiment is different from that of the first embodiment in that various functions are further added to the system of the first embodiment and the positioning means is formed of a flat plate member. Therefore, only these different points will be briefly described below.
The functions added in the second embodiment are (i) a point corresponding to the agglutination reaction information input process in a plurality of inspection devices, (ii) a point in which the inspection devices are arranged in a correct direction in a predetermined area, (iii) ) It is a point to prevent an erroneous input of the visual determination result caused by the inspection device being arranged in the wrong direction in the predetermined area.

(2-1) Configuration of Aggregation Reaction Information Input Processing System FIG. 4A is a configuration diagram of an aggregation reaction information input processing system according to the second embodiment of the present invention, and FIG. 4B is an aggregation of (A). It is a figure explaining operation | movement of the test | inspection request information receiving means in a reaction information input processing system. FIG. 5A is a partial configuration diagram of the agglutination reaction information input processing system according to the second embodiment of the present invention, and FIG. 5B is a display on the display means in the agglutination reaction information input processing system of FIG. It is a figure which shows an example of the display screen displayed.
As shown in FIGS. 4 (A) and 5 (A), this agglutination reaction information input processing system 1 ′ includes a positioning means 5, an internal control means 6 ′ including a database 6d, an inspection request information receiving means 14, and the like. The inspection device reservation setting means 15 is further provided.

  The positioning means 5 is made of a transparent flat plate member made of, for example, an acrylic material as shown in FIG. 5A, and has a housing portion 5a capable of housing the inspection device 2 in a predetermined region 11.

The inspection request information receiving means 14 receives at least one inspection request information including information on at least one person to be inspected and an inspection item, thereby at least dispensing sequence (SEQ) for each inspection device 2 corresponding to each inspection item. The inspection device dispensing information including information on the well position and the person to be inspected is created and registered in the database 6d. The inspection request information is information digitized by means such as OCR.
For example, when the inspection request information receiving means 14 receives the inspection request information as shown in FIG. 4B, the inspection device dispensing information corresponding to HBsAG (HBs antigen) and RAPA (rheumatoid arthritis particle agglutination) Are created and registered in the database 6d.

The inspection device reservation setting unit 15 receives each inspection device identification information 8 read by the identification information reading unit 3 before the visual inspection of the agglutination reaction in each inspection device 2, thereby identifying the inspection device for each inspection device 2. Inspection device association information in which the information 8 and the registered inspection device dispensing information are associated with each other is created and registered in the database.
Here, the image image display unit 6b receives the inspection device identification information 8 read by the identification information reading unit 3 after the inspection device association setting information is generated by the inspection device reservation setting unit 15, and thereby stores the inspection device identification information 8 in the database 6d. Search the stored inspection device association information. When there is inspection device dispensing information associated with the inspection device identification information 8, the image display unit 6 b corresponds the image image 12 of each well W of the inspection device 2 to the predetermined area 11. It is displayed on the display screen 10.

(2-2) Aggregation Reaction Information Input Processing Method By operating the aggregation reaction information input processing system 1 ′ having the above configuration, the aggregation reaction information input processing method according to the second embodiment of the present invention can be implemented. .
6A is a perspective view illustrating a state in which the inspection device of FIG. 5A is arranged in a predetermined region, and FIG. 6B is a partial cross-sectional view taken along line XX ′ in FIG. (C) is a figure which shows an example of the display screen displayed on a display means in the aggregation reaction information input processing system of (A). FIG. 7 is a flowchart for explaining an aggregating reaction information input processing method according to the second embodiment of the present invention.

  First, as shown in FIGS. 4A, 4B, and 7, inspection request information is received (see step S1 in FIG. 7). At this time, the inspection device dispensing information as described above is created by the inspection request information receiving means 14 and registered in the database 6d.

  Next, before visual inspection of the agglutination reaction in each inspection device 2, each inspection device identification information 8 is read by the identification information reading means 3, and inspection device reservation setting is performed (see step S2 in FIG. 7). At this time, the inspection device linking information as described above is registered in the database 6d by the inspection device reservation setting means 15.

  Next, as shown in FIGS. 5A and 7, the display means 4 is prepared, and the display screen 10 is horizontally arranged (see step S3 in FIG. 7).

Next, the inspection device identification information 8 of the inspection device identification member 7 attached to the inspection device 2 to be visually inspected is read again by the identification information reading means 3 (see step S4 in FIG. 7). After the execution of step S4, the image display unit 6a receives the inspection device identification information 8 from the identification information reading unit 3. At this time, the image display unit 6a searches the inspection device association information stored in the database 6d. Then, when there is inspection device dispensing information associated with the inspection device identification information, the inspection device identification information 8 read by the identification information reading means 3 is added to the inspection device identification information 8 as shown in FIGS. An image 12 of each well W of the related inspection device 2 is displayed on the display screen 10.
At this time, the image image display unit 6 a displays a mark 16 on the display screen 10 for arranging the inspection device 2 in the correct direction in the predetermined area 11.

  Thereafter, as shown in FIGS. 5A and 7, the inspection device 2 is positioned and arranged in a predetermined area 11 on the display screen 10 including the image image 12 by putting the inspection device 2 in the housing 5 a. (See step S5 in FIG. 7).

Next, as shown in FIGS. 6A and 7, first, the empty control well CW (for example, the well shown in FIG. 6) of the test device 2 arranged in the predetermined region 11 and in which neither the specimen nor the reagent is dispensed. The input indicator 9 is brought into contact with the upper part of the position <H-12> and an update command is selected. At this time, the agglutination reaction result display unit 6b detects this contact state to determine whether or not the inspection device 2 is arranged in the correct direction in the predetermined region 11. When the inspection device 2 is not arranged in the correct orientation (for example, when the inspection device is arranged with the wrong front-rear direction), the input indicator 9 cannot be used to input a visual determination result. Is configured to do.
Next, the input indicator 9 is brought into contact with the upper portion of each well W (for example, see well position <H-6> in FIG. 2) after the agglutination reaction of the inspection device 2 arranged in the predetermined region 11 (see FIG. 7 (see step S6). Then, the aggregation state (weak positive, positive, retest, hold, negative) of the visual judgment screen 13 displayed adjacent to the image 12 is selected by the input indicator 9 (for example, well position <H-6 in FIG. 6). In the case of>, weak positive is selected as the aggregation state).
At this time, the agglutination reaction result display unit 6b detects the contact state of the input indicator 9 with respect to the upper part of each well W, whereby each corresponding well in the image image 12 below the inspection device 2 arranged in the predetermined region 11 is detected. The visual determination result of the agglutination reaction of W is displayed in a pattern with a color or pattern (for example, in the case of well position <H-6> in FIG. 6, a hatched pattern is displayed).
Further, the end command displayed on the lower side of the visual judgment screen 13 is selected by the input indicator 9. At this time, the determination result recording unit 6c records the pattern-displayed visual determination result in, for example, the database 6d.

(2-3) Effects (i) According to the invention of the second embodiment, the inspection device identification information 8 for each inspection device read by the identification information reading means 3 before the visual inspection of the aggregation reaction in each inspection device 2 The inspection device dispensing information created by the inspection request information receiving means 14 is associated with the inspection device reservation setting means 15 and registered in the database 6d as inspection device association information. Therefore, the consistency between the inspection device identification information 8 of each inspection device 2 and the inspection device dispensing information can be maintained even when the aggregation reaction in the plurality of inspection devices 2 is visually inspected.
(Ii) Further, according to the invention of the second embodiment, the inspection device 2 can be arranged in the correct orientation simply by following the mark 16 on the display screen 10.
(Iii) Further, according to the invention of the second embodiment, the aggregating reaction result display unit 6b prevents an erroneous input of the visual determination result due to the inspection device being disposed in the wrong direction in the predetermined region 11. be able to.

  As mentioned above, although preferable embodiment of this invention was described, the structure of this invention is not limited to these embodiment.

For example, as illustrated in FIG. 8, the inspection device 2 may be configured to include a transparent lid member 18 that is attached to the inspection device main body and has a plurality of recesses 17 that cover each well W from above. . At this time, the agglutination reaction result display unit 6b detects the contact state of the input indicator 9 with respect to the concave portion 17 of each well after the agglutination reaction of the inspection device 2 arranged in the predetermined region 11, thereby the inspection device 2 concerned. The visual determination result of the agglutination reaction of each corresponding well W in the image image 12 in the lower part is displayed as a pattern.
According to this configuration, contamination (foreign matter) into each well W is suppressed by the lid member 18. Further, since the concave portion 17 of the lid member 18 stably receives the contact portion of the input indicator 9, the contact operation of the input indicator 9 with respect to the upper portion of each well W of the inspection device 2 can be stably performed.

  For example, the positioning means is not limited to the flat plate member, and any positioning device may be used as long as the inspection device is positioned in the predetermined area 11. With respect to the other components, various modifications can be created within the scope of the configurations described in the claims.

DESCRIPTION OF SYMBOLS 1 Aggregation reaction information input processing system 2 Inspection device 3 Identification information reading means 4 Display means 5 Positioning means 6 Internal control means 6a Image image display part 6b Aggregation reaction result display part 6c Determination result recording part 7 Inspection device identification member 8 Inspection device identification Information 9 Input indicator 10 Display screen 11 Predetermined area 12 Image image 13 Visual determination screen 14 Inspection request information receiving means 15 Inspection device reservation setting means 16 Marking 17 Recess 18 Lid member 100 Aggregation reaction information input processing system 101 Microplate reader 101a Part 101b glass touch panel part 101c display part 101d operation key part 102 microplate 103 input indicator 104 host computer CW control well W well

Claims (8)

Aggregation reaction for input processing of the obtained agglutination reaction information by visually judging the agglutination reaction occurring in each well in at least one test device having a plurality of wells into which a specimen and a reagent are dispensed An information input processing system,
An inspection device identification member attached to each of the inspection devices and having inspection device identification information for each of the inspection devices;
Identification information reading means for reading inspection device identification information of the inspection device identification member;
A display means equipped with an input indicator and a digitizer, and a display screen in which an input instruction operation can be performed by the input indicator is arranged horizontally;
Positioning means for positioning the inspection device in a predetermined area on the display screen so as to be arranged;
An internal control means for controlling the display means based on the output of the identification information reading means, an input indicator and a digitizer,
The internal control means includes
An image that displays the image of each well of the inspection device related to the inspection device identification information on the display screen corresponding to the predetermined area by receiving the inspection device identification information read by the identification information reading unit. An image display unit;
By detecting the contact state of the input indicator with respect to the upper part of each well after the agglutination reaction of the inspection device arranged in the predetermined region, the agglutination reaction of each corresponding well in the image image of the lower part of the inspection device is detected. Agglutination reaction result display unit for displaying a visual judgment result in a pattern;
A determination result recording unit that records a visual determination result displayed in a pattern by the agglutination reaction result display unit. Aggregation reaction for input processing of the obtained agglutination reaction information by visually judging the agglutination reaction occurring in each well in at least one test device having a plurality of wells into which a specimen and a reagent are dispensed An information input processing system,
By receiving inspection request information including information on at least one or more inspected persons and inspection items, for each inspection device corresponding to each inspection item, an inspection including at least a dispensing sequence, well positions, and information on the inspected persons An inspection request information receiving means for creating device dispensing information and registering it in the database;
An inspection device identification member attached to each of the inspection devices and having inspection device identification information for each of the inspection devices;
Identification information reading means for reading inspection device identification information of the inspection device identification member;
Before the visual inspection of the agglutination reaction in each inspection device, each inspection device identification information read by the identification information reading means is received, whereby the inspection device identification information and the inspection device dispensing information for each inspection device are obtained. An inspection device reservation setting unit for creating the associated inspection device association information and registering it in the database;
A display means equipped with an input indicator and a digitizer, and a display screen in which an input instruction operation can be performed by the input indicator is arranged horizontally;
Positioning means for positioning the inspection device in a predetermined area on the display screen so as to be arranged;
An internal control means for controlling the display means based on the output of the identification information reading means, an input indicator and a digitizer,
The internal control means includes
After the inspection device association information is created by the inspection device reservation setting means, the inspection device identification information read by the identification information reading means is further received to search the inspection device association information stored in the database. When there is inspection device dispensing information associated with the inspection device identification information, an image image display unit that displays an image of each well of the inspection device on the display screen corresponding to the predetermined area When,
By detecting the contact state of the input indicator with respect to the upper part of each well after the agglutination reaction of the inspection device arranged in the predetermined region, the agglutination reaction of each corresponding well in the image image of the lower part of the inspection device is detected. Agglutination reaction result display unit for displaying a visual judgment result in a pattern;
A determination result recording unit that records a visual determination result displayed in a pattern by the agglutination reaction result display unit.   The agglutination reaction result display unit determines whether the inspection device is arranged in the correct direction in the predetermined region, and when the inspection device is not arranged in the correct direction, the visual determination result by the input indicator The agglutination reaction information input processing system according to claim 1 or 2, wherein the input instruction is not allowed to be performed.   The said image display part displays the mark for arrange | positioning the said test | inspection device in the correct direction in the said predetermined area | region on the said display screen, The any one of Claims 1-3 characterized by the above-mentioned. Aggregation reaction information input processing system.   The agglomeration reaction information input processing system according to any one of claims 1 to 4, wherein the positioning means is made of a transparent flat plate member having an accommodating portion capable of accommodating the inspection device in the predetermined area. The inspection device includes a lid member having a plurality of recesses that are attached to the inspection device body and cover each well from above;
The agglutination reaction result display unit detects the contact state of the input indicator with respect to the concave portion of each well after the agglutination reaction of the inspection device arranged in the predetermined region, whereby an image image of the lower part of the inspection device The agglutination reaction information input processing system according to any one of claims 1 to 5, wherein the visual determination result of the agglutination reaction of each corresponding well is displayed as a pattern. A method of inputting and processing the obtained agglutination reaction information by visually judging the agglutination reaction occurring in each well in at least one test device having a plurality of wells into which a specimen and a reagent are dispensed. ,
(A) A step of preparing a display means equipped with an input indicator and a digitizer and having a display screen capable of performing an input instruction by the input indicator, and arranging the display screen horizontally;
(B) reading the inspection device identification information of the inspection device identification member attached to each of the inspection devices with an identification information reading unit;
(C) After the execution of the step (b), an image of each well of the inspection device related to the read inspection device identification information is displayed on the display screen, and then a predetermined on the display screen including the image image Positioning and placing the inspection device in a region;
(D) contacting the input indicator with the upper part of each well after the agglutination reaction of the inspection device arranged in the predetermined region,
After the execution of the step (d), the visual determination result of the aggregation reaction of each corresponding well in the image image below the inspection device arranged in the predetermined region is displayed in a pattern. A method of inputting and processing the obtained agglutination reaction information by visually judging the agglutination reaction occurring in each well in at least one test device having a plurality of wells into which a specimen and a reagent are dispensed. ,
(A) Receiving inspection request information including information on at least one or more inspected persons and inspection items, and for each inspection device corresponding to each inspection item, at least dispensing sequence, well position, and information on the inspected person Creating inspection device dispensing information including it and registering it in the database;
(B) Before the visual inspection of the agglutination reaction in each inspection device, the inspection device identification information of the inspection device identification member attached to each inspection device is read by an identification information reading unit, and each of the inspection device identification information and the inspection device is read Creating inspection device association information associated with dispensing information and registering it in the database, and performing inspection device reservation setting;
(C) preparing a display means equipped with an input indicator and a digitizer and having a display screen capable of performing an input instruction by the input indicator, and arranging the display screen horizontally;
(D) further reading the inspection device identification information of the inspection device identification member attached to the inspection device to be visually inspected by the identification information reading means;
(E) After the execution of the step (d), an image of each well of the inspection device related to the read inspection device identification information is displayed on the display screen, and then a predetermined on the display screen including the image image Positioning and placing the inspection device in a region;
(F) contacting the input indicator with the upper part of each well after the agglutination reaction of the inspection device arranged in the predetermined region,
After the execution of the step (f), the visual determination result of the aggregation reaction of each corresponding well in the image image below the inspection device arranged in the predetermined region is displayed in a pattern.

Images