JP2012125402A5 - Endoscope system, processor device for endoscope system, and method for operating endoscope system - Google Patents
Endoscope system, processor device for endoscope system, and method for operating endoscope system Download PDFInfo
- Publication number
- JP2012125402A5 JP2012125402A5 JP2010279512A JP2010279512A JP2012125402A5 JP 2012125402 A5 JP2012125402 A5 JP 2012125402A5 JP 2010279512 A JP2010279512 A JP 2010279512A JP 2010279512 A JP2010279512 A JP 2010279512A JP 2012125402 A5 JP2012125402 A5 JP 2012125402A5
- Authority
- JP
- Japan
- Prior art keywords
- wavelength range
- signal
- light
- illumination light
- oxygen saturation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Description
上記目的を達成するために、本発明の内視鏡システムは、血中ヘモグロビンの酸素飽和度の変化により吸光係数が変化する第１の波長範囲と前記第１の波長範囲と異なる第２の波長範囲を含む第１の照明光を被検体内に照射する第１の照明手段と、前記第１の照明光における前記第２の波長範囲の光量分布と一定の関係がある光量分布を有する第２の照明光を被検体内に照射する第２の照明手段と、前記第２の波長範囲の光を透過させる透過フィルタが設けられた補正用画素を有するカラーの撮像素子を用いて、被検体内で反射した第１の照明光を撮像して第１の画像信号を取得するとともに、被検体内で反射した第２の照明光を撮像して第２の画像信号を取得する画像信号取得手段と、前記第１の画像信号のうち前記補正用画素から出力される信号と、前記第２の画像信号のうち前記補正用画素から出力される信号とに基づいて、前記第１及び第２の照明光間の光量比のズレに基づく信号値のズレを無くすように、前記第１または第２の画像信号を補正する信号補正手段と、前記補正後の第１及び第２の画像信号を用いて、酸素飽和度を算出する酸素飽和度算出手段と、前記酸素飽和度の分布を表示する表示手段とを備えることを特徴とする。
In order to achieve the above object, an endoscope system according to the present invention includes a first wavelength range in which an extinction coefficient changes due to a change in oxygen saturation of blood hemoglobin, and a second wavelength different from the first wavelength range. A first illuminating unit that irradiates a subject with first illumination light including a range, and a second light amount distribution having a certain relationship with the light amount distribution in the second wavelength range in the first illumination light. Using a color imaging device having a correction pixel provided with a second illumination means for irradiating the illumination light into the subject and a transmission filter for transmitting the light in the second wavelength range. An image signal acquisition unit that captures the first illumination light reflected by the first object to obtain a first image signal, and that captures the second illumination light reflected from the subject and obtains the second image signal; , Output from the correction pixel of the first image signal. And a signal value based on a deviation in the light amount ratio between the first and second illumination lights is eliminated based on the output signal and the signal output from the correction pixel in the second image signal. In addition, signal correction means for correcting the first or second image signal, oxygen saturation calculation means for calculating oxygen saturation using the corrected first and second image signals, and the oxygen And a display means for displaying a distribution of saturation.
前記第１の照明光は、４６０〜４８０ｎｍの波長範囲を有する第１励起光を蛍光体に当てたときに励起発光する白色光であり、前記第２の照明光は、４４０〜４６０ｎｍの波長範囲を有する第２励起光を蛍光体に当てたときに励起発光する白色光であり、前記第１励起光を前記蛍光体に当てたときの蛍光スペクトルと前記第２励起光を前記蛍光体に当てたときの蛍光スペクトルとは概形が変わらないことが好ましい。
The first illumination light is white light that is excited and emitted when the first excitation light having a wavelength range of 460 to 480 nm is applied to the phosphor, and the second illumination light is a wavelength range of 440 to 460 nm. White light that is excited and emitted when the phosphor is applied with the second excitation light having a fluorescence spectrum when the first excitation light is applied to the phosphor and the second excitation light is applied to the phosphor. It is preferable that the approximate shape of the fluorescence spectrum does not change.
本発明の内視鏡システムのプロセッサ装置は、血中ヘモグロビンの酸素飽和度の変化により吸光係数が変化する第１の波長範囲と前記第１の波長範囲と異なる第２の波長範囲を含む第１の照明光と、前記第２の波長範囲において前記第１の照明光の光量分布と一定の関係がある光量分布を有する第２の照明光とを被検体内に照射し、前記第２の波長範囲の光を透過させる透過フィルタが設けられた補正用画素を有するカラーの撮像素子を用いて、被検体内で反射した第１の照明光を撮像して第１の画像信号を取得するとともに、被検体内で反射した第２の照明光を撮像して第２の画像信号を取得内視鏡装置から、前記第１及び第２の画像信号を受信する受信手段と、前記第１の画像信号のうち前記補正用画素から出力される信号と、前記第２の画像信号のうち前記補正用画素から出力される信号とに基づいて、前記第１及び第２の照明光間の光量比のズレに基づく信号値のズレを無くすように、前記第１または第２の画像信号を補正する信号補正手段と、前記補正後の第１及び第２の画像信号を用いて、酸素飽和度を算出する酸素飽和度算出手段とを備えることを特徴とする。
The processor device of the endoscope system of the present invention includes a first wavelength range in which an extinction coefficient changes due to a change in oxygen saturation of blood hemoglobin, and a first wavelength range including a second wavelength range different from the first wavelength range. And the second illumination light having a light amount distribution having a certain relationship with the light amount distribution of the first illumination light in the second wavelength range, and the second wavelength. Using a color imaging element having a correction pixel provided with a transmission filter that transmits light in a range, the first illumination light reflected in the subject is imaged to obtain a first image signal, and Receiving means for receiving the first and second image signals from the endoscope apparatus, imaging the second illumination light reflected in the subject and acquiring the second image signal; and the first image signal Among the signals output from the correction pixels, and the second Based on a signal output from the correction pixel in the image signal, the first or second signal value may be shifted based on a shift in a light amount ratio between the first and second illumination lights. Signal correction means for correcting the image signal, and oxygen saturation calculation means for calculating the oxygen saturation using the corrected first and second image signals.
本発明の内視鏡システムの作動方法は、照明手段が、血中ヘモグロビンの酸素飽和度の変化により吸光係数が変化する第１の波長範囲と前記第１の波長範囲と異なる第２の波長範囲を含む第１の照明光と、前記第２の波長範囲において前記第１の照明光の光量分布と一定の関係がある光量分布を有する第２の照明光とを、それぞれ別々に発するステップと、画像信号取得手段が、前記第２の波長範囲の光を透過させる透過フィルタが設けられた補正用画素を有するカラーの撮像素子を用いて、被検体内で反射した第１の照明光を撮像して第１の画像信号を取得するとともに、被検体内で反射した第２の照明光を撮像して第２の画像信号を取得するステップと、信号補正手段が、前記第１の画像信号のうち前記補正用画素から出力される信号と、前記第２の画像信号のうち前記補正用画素から出力される信号とに基づいて、前記第１及び第２の照明光間の光量比のズレに基づく信号値のズレを無くすように、前記第１または第２の画像信号を補正するステップと、酸素飽和度算出手段が、前記補正後の第１及び第２の画像信号を用いて、酸素飽和度を算出するステップとを有することを特徴とする。 In the operating method of the endoscope system according to the present invention, the illumination means has a first wavelength range in which an extinction coefficient changes due to a change in oxygen saturation of blood hemoglobin and a second wavelength range different from the first wavelength range. first illumination light including the steps of emitting a second illumination light having a light intensity distribution and constant relationship light amount distribution of the first illumination light at the second wavelength range, respectively separately, The image signal acquisition means images the first illumination light reflected in the subject using a color imaging element having a correction pixel provided with a transmission filter that transmits light in the second wavelength range. Acquiring a first image signal, capturing a second image signal by imaging the second illumination light reflected in the subject, and a signal correction means comprising: A signal output from the correction pixel; Based on a signal output from the correction pixel in the second image signal, the shift of the signal value based on the shift of the light amount ratio between the first and second illumination lights is eliminated. and correcting the first or second image signals, the oxygen saturation calculating unit, using the first and second image signal after the correction, and characterized by a step of calculating the oxygen saturation To do.
Claims (9)
前記第１の照明光における前記第２の波長範囲の光量分布と一定の関係がある光量分布を有する第２の照明光を被検体内に照射する第２の照明手段と、
前記第２の波長範囲の光を透過させる透過フィルタが設けられた補正用画素を有するカラーの撮像素子を用いて、被検体内で反射した第１の照明光を撮像して第１の画像信号を取得するとともに、被検体内で反射した第２の照明光を撮像して第２の画像信号を取得する画像信号取得手段と、
前記第１の画像信号のうち前記補正用画素から出力される信号と、前記第２の画像信号のうち前記補正用画素から出力される信号とに基づいて、前記第１及び第２の照明光間の光量比のズレに基づく信号値のズレを無くすように、前記第１または第２の画像信号を補正する信号補正手段と、
前記補正後の第１及び第２の画像信号を用いて、酸素飽和度を算出する酸素飽和度算出手段と、
前記酸素飽和度の分布を表示する表示手段とを備えることを特徴とする内視鏡システム。 A first illumination light that irradiates a subject with first illumination light that includes a first wavelength range in which an absorption coefficient changes due to a change in oxygen saturation of blood hemoglobin and a second wavelength range that is different from the first wavelength range. Lighting means,
Second illumination means for irradiating a subject with second illumination light having a light amount distribution having a certain relationship with a light amount distribution in the second wavelength range in the first illumination light;
A first image signal obtained by imaging the first illumination light reflected in the subject using a color imaging device having a correction pixel provided with a transmission filter that transmits light in the second wavelength range. Image signal acquisition means for capturing the second illumination light reflected in the subject and acquiring the second image signal;
The first and second illumination lights based on a signal output from the correction pixel in the first image signal and a signal output from the correction pixel in the second image signal. Signal correcting means for correcting the first or second image signal so as to eliminate a signal value shift based on a shift in the light amount ratio between the first and second image signals;
Oxygen saturation calculating means for calculating oxygen saturation using the corrected first and second image signals;
An endoscope system comprising: display means for displaying the distribution of the oxygen saturation.
前記透過フィルタは、前記第１または第２の照明光のうち赤色帯域の光を透過させるＲ色のフィルタであることを特徴とする請求項１記載の内視鏡システム。 The first wavelength range is included in a blue band;
The endoscope system according to claim 1, wherein the transmission filter is an R-color filter that transmits light in a red band of the first or second illumination light.
前記第２の照明光は、４４０〜４６０ｎｍの波長範囲を有する第２励起光を蛍光体に当てたときに励起発光する白色光であり、
前記第１励起光を前記蛍光体に当てたときの蛍光スペクトルと前記第２励起光を前記蛍光体に当てたときの蛍光スペクトルとは概形が変わらないことを特徴とする請求項１ないし３いずれか１項記載の内視鏡システム。 The first illumination light is white light that is excited and emitted when the first excitation light having a wavelength range of 460 to 480 nm is applied to the phosphor.
The second illumination light is white light that is excited and emitted when the second excitation light having a wavelength range of 440 to 460 nm is applied to the phosphor.
4. The general shape of the fluorescence spectrum when the first excitation light is applied to the phosphor and the fluorescence spectrum when the second excitation light is applied to the phosphor are the same. The endoscope system according to any one of the preceding claims.
前記補正後の第１及び第２の画像信号間の信号比を算出する信号比算出部と、
前記信号比と酸素飽和度との相関関係を記憶する相関関係記憶部と、
前記相関関係記憶部に記憶された相関関係から、前記信号比算出部で算出した信号比に対応する酸素飽和度を求める酸素飽和度算出部とを備えることを特徴とする請求項１ないし５いずれか１項記載の内視鏡システム。 The oxygen saturation calculating means includes
A signal ratio calculation unit for calculating a signal ratio between the corrected first and second image signals;
A correlation storage unit for storing a correlation between the signal ratio and oxygen saturation;
6. An oxygen saturation calculation unit that obtains an oxygen saturation corresponding to the signal ratio calculated by the signal ratio calculation unit from the correlation stored in the correlation storage unit. The endoscope system according to claim 1.
前記第１の画像信号のうち前記補正用画素から出力される信号と、前記第２の画像信号のうち前記補正用画素から出力される信号とに基づいて、前記第１及び第２の照明光間の光量比のズレに基づく信号値のズレを無くすように、前記第１または第２の画像信号を補正する信号補正手段と、
前記補正後の第１及び第２の画像信号を用いて、酸素飽和度を算出する酸素飽和度算出手段とを備えることを特徴とする内視鏡システムのプロセッサ装置。 A first illumination light including a first wavelength range in which an extinction coefficient changes due to a change in oxygen saturation of blood hemoglobin, a second wavelength range different from the first wavelength range, and the second wavelength range. A transmission filter is provided that irradiates the subject with second illumination light having a light quantity distribution having a certain relationship with the light quantity distribution of the first illumination light, and transmits light in the second wavelength range. Using a color imaging element having a correction pixel, the first illumination light reflected in the subject is imaged to obtain a first image signal, and the second illumination light reflected in the subject is used. Receiving means for receiving the first and second image signals from an endoscope apparatus that captures an image and obtains a second image signal;
The first and second illumination lights based on a signal output from the correction pixel in the first image signal and a signal output from the correction pixel in the second image signal. Signal correcting means for correcting the first or second image signal so as to eliminate a signal value shift based on a shift in the light amount ratio between the first and second image signals;
An endoscopic system processor comprising: an oxygen saturation calculating unit that calculates oxygen saturation using the corrected first and second image signals.
画像信号取得手段が、前記第２の波長範囲の光を透過させる透過フィルタが設けられた補正用画素を有するカラーの撮像素子を用いて、被検体内で反射した第１の照明光を撮像して第１の画像信号を取得するとともに、被検体内で反射した第２の照明光を撮像して第２の画像信号を取得するステップと、
信号補正手段が、前記第１の画像信号のうち前記補正用画素から出力される信号と、前記第２の画像信号のうち前記補正用画素から出力される信号とに基づいて、前記第１及び第２の照明光間の光量比のズレに基づく信号値のズレを無くすように、前記第１または第２の画像信号を補正するステップと、
酸素飽和度算出手段が、前記補正後の第１及び第２の画像信号を用いて、酸素飽和度を算出するステップとを有することを特徴とする内視鏡システムの作動方法。 The illumination means includes a first illumination light including a first wavelength range in which an extinction coefficient changes due to a change in oxygen saturation of blood hemoglobin, a second wavelength range different from the first wavelength range, and the second illumination light. a step of emitting a second illumination light having a light intensity distribution and constant relationship light amount distribution of the first illumination light in the wavelength range, on separate,
The image signal acquisition means images the first illumination light reflected in the subject using a color imaging element having a correction pixel provided with a transmission filter that transmits light in the second wavelength range. to obtain the first image signal Te, obtaining a second image signal by imaging the second illumination light reflected by the object,
The signal correction means is configured to output the first and second signals based on a signal output from the correction pixel in the first image signal and a signal output from the correction pixel in the second image signal. so as to eliminate the deviation of the signal values based on the deviation of the light amount ratio between the second illuminating light, and correcting the first or second image signals,
And a step of calculating oxygen saturation using the corrected first and second image signals. 2. A method of operating an endoscope system, comprising:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010279512A JP5558331B2 (en) | 2010-12-15 | 2010-12-15 | Endoscope system, processor device for endoscope system, and method for operating endoscope system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010279512A JP5558331B2 (en) | 2010-12-15 | 2010-12-15 | Endoscope system, processor device for endoscope system, and method for operating endoscope system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012125402A JP2012125402A (en) | 2012-07-05 |
| JP2012125402A5 true JP2012125402A5 (en) | 2013-06-13 |
| JP5558331B2 JP5558331B2 (en) | 2014-07-23 |
Family
ID=46643161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010279512A Active JP5558331B2 (en) | 2010-12-15 | 2010-12-15 | Endoscope system, processor device for endoscope system, and method for operating endoscope system |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5558331B2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5997643B2 (en) * | 2013-03-26 | 2016-09-28 | 富士フイルム株式会社 | ENDOSCOPE SYSTEM, PROCESSOR DEVICE, AND OPERATION METHOD |
| JP6129686B2 (en) * | 2013-08-23 | 2017-05-17 | 富士フイルム株式会社 | Endoscope system, processor device, operation method, and table creation method |
| JP6140056B2 (en) | 2013-09-26 | 2017-05-31 | 富士フイルム株式会社 | Endoscope system, processor device for endoscope system, method for operating endoscope system, method for operating processor device |
| JP6276149B2 (en) * | 2014-09-12 | 2018-02-07 | 富士フイルム株式会社 | Endoscope system and operating method thereof |
| JP6866531B2 (en) | 2018-03-06 | 2021-04-28 | 富士フイルム株式会社 | Medical image processing system and endoscopic system |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2774788B2 (en) * | 1995-11-27 | 1998-07-09 | 株式会社東芝 | Electronic endoscope device |
| JP4270634B2 (en) * | 1999-03-18 | 2009-06-03 | オリンパス株式会社 | Endoscope device |
-
2010
- 2010-12-15 JP JP2010279512A patent/JP5558331B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6204314B2 (en) | Electronic endoscope system | |
| JP5303012B2 (en) | Endoscope system, processor device for endoscope system, and method for operating endoscope system | |
| US20170135555A1 (en) | Endoscope system, image processing device, image processing method, and computer-readable recording medium | |
| JP5654511B2 (en) | Endoscope system, processor device for endoscope system, and method for operating endoscope system | |
| JP4727374B2 (en) | Electronic endoscope device | |
| US9629527B2 (en) | Endoscope system, processor device of endoscope system, and image processing method | |
| WO2015005277A1 (en) | Light source device | |
| US9271635B2 (en) | Fluorescence endoscope apparatus | |
| JP2012130504A5 (en) | ||
| JP5887367B2 (en) | Processor device, endoscope system, and operation method of endoscope system | |
| US20120179050A1 (en) | Endoscope diagnosis system | |
| JP2012143337A5 (en) | ||
| US20130250079A1 (en) | Fluorescence endoscope apparatus | |
| JP6690003B2 (en) | Endoscope system and operating method thereof | |
| JP2015196004A5 (en) | ||
| WO2012056970A1 (en) | Fluorescence observation device | |
| JP6085649B2 (en) | Endoscope light source device and endoscope system | |
| JP2012125402A5 (en) | Endoscope system, processor device for endoscope system, and method for operating endoscope system | |
| JPWO2011135992A1 (en) | Image processing apparatus and fluorescence observation apparatus | |
| JP5930474B2 (en) | Endoscope system and operating method thereof | |
| JP2016192985A (en) | Endoscope system, processor device, and operation method of endoscope system | |
| US20160302652A1 (en) | Fluorescence observation apparatus | |
| JP6979510B2 (en) | Endoscope system and how to operate it | |
| JP2016049447A (en) | Light source device for endoscope and endoscope system | |
| JP5558331B2 (en) | Endoscope system, processor device for endoscope system, and method for operating endoscope system |