JP2011516038A - バイオマーカー - Google Patents

バイオマーカー Download PDF

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Publication number
JP2011516038A
JP2011516038A JP2010550628A JP2010550628A JP2011516038A JP 2011516038 A JP2011516038 A JP 2011516038A JP 2010550628 A JP2010550628 A JP 2010550628A JP 2010550628 A JP2010550628 A JP 2010550628A JP 2011516038 A JP2011516038 A JP 2011516038A
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JP
Japan
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grn
level
acd
antibody
subject
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Pending
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JP2010550628A
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Japanese (ja)
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JP2011516038A5 (https=
Inventor
クリストファー ジョセフ ペンバートン，
アーサー マーク リチャーズ，
マイケル ゲイリー ニコールズ，
ティモシー グラント ヤンデル，
Original Assignee
オタゴ イノベーション リミテッド
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Application filed by オタゴ イノベーション リミテッド filed Critical オタゴ イノベーション リミテッド
Publication of JP2011516038A publication Critical patent/JP2011516038A/ja
Publication of JP2011516038A5 publication Critical patent/JP2011516038A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/60—Growth-hormone releasing factors (GH-RF) (Somatoliberin)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2010550628A 2008-03-12 2009-03-12 バイオマーカー Pending JP2011516038A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3576108P 2008-03-12 2008-03-12
US61/035,761 2008-03-12
PCT/NZ2009/000032 WO2009113880A1 (en) 2008-03-12 2009-03-12 Biomarkers

Publications (2)

Publication Number Publication Date
JP2011516038A true JP2011516038A (ja) 2011-05-26
JP2011516038A5 JP2011516038A5 (https=) 2012-05-10

Family

ID=41065428

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010550628A Pending JP2011516038A (ja) 2008-03-12 2009-03-12 バイオマーカー

Country Status (7)

Country Link
US (1) US8507209B2 (https=)
EP (1) EP2265642A4 (https=)
JP (1) JP2011516038A (https=)
CN (1) CN101977933A (https=)
AU (1) AU2009224114B2 (https=)
CA (1) CA2715921A1 (https=)
WO (1) WO2009113880A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5308328B2 (ja) 2006-04-04 2013-10-09 シングレックス，インコーポレイテッド トロポニンの分析のための高感度のシステムおよび方法
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
WO2008030122A1 (en) 2006-09-07 2008-03-13 University Of Otago Biomarkers
AU2009224113B2 (en) * 2008-03-12 2013-02-21 Otago Innovation Limited Biomarkers
WO2010144358A1 (en) 2009-06-08 2010-12-16 Singulex, Inc. Highly sensitive biomarker panels
US20140148348A1 (en) 2010-01-13 2014-05-29 Christine Kuslich Dectection of gastrointestinal disorders
EP2542696B1 (en) 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Biomarkers for theranostics
JP2013526852A (ja) 2010-04-06 2013-06-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス 疾患に対する循環バイオマーカー
KR101313184B1 (ko) * 2010-06-24 2013-09-30 한국표준과학연구원 질병 지표 검출 키트 및 질병 지표 검출 방법
DK2596010T3 (en) 2010-07-19 2017-07-31 Otago Innovation Ltd SIGNAL biomarkers
WO2012122094A2 (en) * 2011-03-04 2012-09-13 The Johns Hopkins University Biomarkers of cardiac ischemia
EP2592423A1 (en) 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment
EP2592422A1 (en) 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment
US10114028B2 (en) * 2012-03-20 2018-10-30 Upstream Medical Technologies Limited Biomarkers for pneumonia and acute decompensated heart failure
KR102039522B1 (ko) * 2013-06-03 2019-11-26 휴렛-팩커드 디벨롭먼트 컴퍼니, 엘.피. 근거리 무선 통신(ｎｆｃ)을 이용한 ｎｆｃ 태그의 기록방법 및 장치
EP3888021B1 (en) 2018-11-30 2024-02-21 Caris MPI, Inc. Next-generation molecular profiling
CA3163319A1 (en) 2019-12-02 2021-06-10 Caris Mpi, Inc. Pan-cancer platinum response predictor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005052593A1 (en) * 2003-10-29 2005-06-09 The University Of Leicester Detection

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5843708A (en) 1988-01-05 1998-12-01 Ciba-Geigy Corporation Chimeric antibodies
GB8800077D0 (en) 1988-01-05 1988-02-10 Ciba Geigy Ag Novel chimeric antibodies
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
WO1991017440A1 (en) 1990-05-07 1991-11-14 Immunomedics, Inc. Improved method for radiolabeling monovalent antibody fragments
CA2072758A1 (en) 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
US5221685A (en) 1991-02-01 1993-06-22 Ube Industries, Ltd. Thiazoline derivative, process for preparing the same and chemical for controlling noxious organisms containing the same
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
CA2107894C (en) 1991-04-10 2003-10-14 Kenneth F. Buechler Crosstalk inhibitors and their uses
EP0579767B1 (en) 1991-04-11 2000-08-23 Biosite Diagnostics Inc. Novel conjugates and assays for simultaneous detection of multiple ligands
US6019944A (en) 1992-05-21 2000-02-01 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
EP0700521B1 (en) 1993-05-28 2003-06-04 Baylor College Of Medicine Method and mass spectrometer for desorption and ionization of analytes
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
ATE224053T1 (de) 1993-11-12 2002-09-15 Inverness Medical Switzerland Vorrichtung zum ablesen von teststreifen
ES2145034T3 (es) 1993-11-12 2000-07-01 Unilever Nv Dispositivos analiticos y procedimientos para el uso de los mismos.
US5647124A (en) 1994-04-25 1997-07-15 Texas Instruments Incorporated Method of attachment of a semiconductor slotted lead to a substrate
GB9419267D0 (en) 1994-09-23 1994-11-09 Unilever Plc Assay devices
US5792294A (en) 1995-11-16 1998-08-11 Otis Elevator Company Method of replacing sheave liner
US5719600A (en) 1995-12-12 1998-02-17 Hewlett-Packard Company Gradient calculation system and method
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
NZ516848A (en) 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
GB9717926D0 (en) 1997-08-22 1997-10-29 Micromass Ltd Methods and apparatus for tandem mass spectrometry
JP2002502086A (ja) 1998-01-23 2002-01-22 アナリティカ オブ ブランフォード インコーポレーテッド 表面からの質量分光測定
US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
AU2002366875B2 (en) 2001-12-21 2008-08-21 Sense Proteomic Limited Probe for mass spectrometry
AUPS169202A0 (en) 2002-04-11 2002-05-16 Goetze, Jens Peter Neuropeptide assay
US6780645B2 (en) 2002-08-21 2004-08-24 Lifescan, Inc. Diagnostic kit with a memory storing test strip calibration codes and related methods
US7045366B2 (en) 2003-09-12 2006-05-16 Ciphergen Biosystems, Inc. Photocrosslinked hydrogel blend surface coatings
US7341838B2 (en) 2003-04-17 2008-03-11 Biosite Incorporated Polypeptides related to natriuretic peptides and methods of their identification and use
JP2008500949A (ja) 2003-07-02 2008-01-17 ジェネンテック・インコーポレーテッド 腫瘍の診断と治療のための組成物と方法
US7176292B2 (en) 2003-09-11 2007-02-13 Dialean, Ltd. Ghrelin variant protein
CA2575402A1 (en) 2004-08-05 2006-02-09 Genentech, Inc. Humanized anti-cmet antagonists
WO2006096847A1 (en) * 2005-03-09 2006-09-14 The Board Of Trustees Of The Leland Stanford Junior University Obestatin and its uses
JP2006292623A (ja) 2005-04-13 2006-10-26 Univ Of Dundee 心不全における突然死のマーカー
EP1731910A1 (en) 2005-06-07 2006-12-13 F. Hoffmann-La Roche Ag Use of NT-proANP and NT-proBNP for diagnosing cardiac diseases
GB0712670D0 (en) 2007-06-29 2007-08-08 King S College London Isolated peptides and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005052593A1 (en) * 2003-10-29 2005-06-09 The University Of Leicester Detection
US20050244904A1 (en) * 2003-10-29 2005-11-03 Leong Ng Diagnostics based on signal peptide detection

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6013063237; ＧＵＥＯＲＧＵＩＥＶ，　Ｍ．　ｅｔ　ａｌ．: 'Ａｃｃｅｓｓｉｏｎ　Ｎｏ．　Ａ２Ｔ３Ｘ２，　ＤＥＦＩＮＩＴＩＯＮ：　Ｇｈｒｅｌｉｎ　（Ｆｒａｇｍｅｎｔ）' Ｄａｔａｂａｓｅ　ＵｎｉＰｒｏｔ　［ｏｎｌｉｎｅ］ , 20080205 *
JPN6013063239; ＫＯＲＢＯＮＩＴＳ，　Ｍ．　ｅｔ　ａｌ．: 'Ｇｈｒｅｌｉｎ-ａ　ｈｏｒｍｏｎｅ　ｗｉｔｈ　ｍｕｌｔｉｐｌｅ　ｆｕｎｃｔｉｏｎｓ' Ｆｒｏｎｔｉｅｒｓ　ｉｎ　Ｎｅｕｒｏｅｎｄｏｃｒｉｎｏｌｏｇｙ Ｖｏｌ．２５，　Ｎｏ．１, 200404, ｐ．２７-６８ *
JPN6013063240; ＹＡＳＵＤＡ，　Ｓ．　ｅｔ　ａｌ．: 'Ｄｅｃｒｅａｓｅｄ　Ｓｅｒｕｍ　Ｇｈｒｅｌｉｎ　Ｌｅｖｅｌ　ｉｎ　Ｐａｔｉｅｎｔｓ　ｗｉｔｈ　Ａｃｕｔｅ　Ｍｙｏｃａｒｄｉａｌ　Ｉｎｆａｒｃｔｉｏｎ　：　Ｉｔｓ　Ａｓｓｏｃｉａｔｉｏｎ　ｗｉｔｈ　ｔｈ' Ｃｉｒｃｕｌａｔｉｏｎ　Ｊｏｕｒｎａｌ Ｖｏｌ．６８，　Ｎｏ．Ｓｕｐｐｌｅｍｅｎｔ＿Ｉ, 20040301, ｐ．１３４ *

Also Published As

Publication number Publication date
EP2265642A4 (en) 2012-05-02
EP2265642A1 (en) 2010-12-29
US20110008808A1 (en) 2011-01-13
CN101977933A (zh) 2011-02-16
WO2009113880A1 (en) 2009-09-17
CA2715921A1 (en) 2009-09-17
AU2009224114B2 (en) 2013-02-21
US8507209B2 (en) 2013-08-13
AU2009224114A1 (en) 2009-09-17

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