JP2011509281A5 - - Google Patents
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- Publication number
- JP2011509281A5 JP2011509281A5 JP2010541823A JP2010541823A JP2011509281A5 JP 2011509281 A5 JP2011509281 A5 JP 2011509281A5 JP 2010541823 A JP2010541823 A JP 2010541823A JP 2010541823 A JP2010541823 A JP 2010541823A JP 2011509281 A5 JP2011509281 A5 JP 2011509281A5
- Authority
- JP
- Japan
- Prior art keywords
- homeoprotein
- composition according
- retinal ganglion
- family
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000009331 Homeodomain Proteins Human genes 0.000 claims 5
- 108010048671 Homeodomain Proteins Proteins 0.000 claims 5
- 208000003098 Ganglion Cysts Diseases 0.000 claims 3
- 208000005400 Synovial Cyst Diseases 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 230000002207 retinal Effects 0.000 claims 3
- 235000020945 retinal Nutrition 0.000 claims 3
- 210000002569 neurons Anatomy 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 108091016752 Bicoid family Proteins 0.000 claims 1
- 102000032454 Bicoid family Human genes 0.000 claims 1
- 208000010412 Glaucoma Diseases 0.000 claims 1
- 101700070147 OTX2 Proteins 0.000 claims 1
- 230000001537 neural Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000004083 survival Effects 0.000 claims 1
Claims (5)
- 網膜神経節ニューロン変性の予防又は治療のための、ビコイドファミリーのホメオタンパク質を含む医薬組成物。
- 前記網膜神経節ニューロン変性が緑内障において生じることを特徴とする請求項１に記載の医薬組成物。
- 培養網膜神経節ニューロンの生存を増大させるための、ビコイドファミリーのホメオタンパク質を含む組成物。
- 前記ホメオタンパク質がOtxサブファミリーに属することを特徴とする請求項１〜３のいずれか１項に記載の組成物。
- 前記ホメオタンパク質がOtx2ホメオタンパク質であることを特徴とする請求項４に記載の組成物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0800110A FR2926023B1 (fr) | 2008-01-09 | 2008-01-09 | Utilisation d'une homoproteine de la famille bicoid pour le traitement du glaucome. |
| FR0800110 | 2008-01-09 | ||
| PCT/FR2009/000031 WO2009106767A2 (fr) | 2008-01-09 | 2009-01-09 | Utilisation d'une homeoproteine de la famille bicoïd pour la prevention ou le traitement de la degenerescence des neurones ganglionnaires retiniens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011509281A JP2011509281A (ja) | 2011-03-24 |
| JP2011509281A5 true JP2011509281A5 (ja) | 2012-02-23 |
| JP5851692B2 JP5851692B2 (ja) | 2016-02-03 |
Family
ID=39620167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010541823A Active JP5851692B2 (ja) | 2008-01-09 | 2009-01-09 | 網膜神経節ニューロン変性を予防又は治療するためのビコイドファミリーのホメオタンパク質の使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10722554B2 (ja) |
| EP (1) | EP2240197B1 (ja) |
| JP (1) | JP5851692B2 (ja) |
| CA (1) | CA2711866C (ja) |
| DK (1) | DK2240197T3 (ja) |
| ES (1) | ES2542518T3 (ja) |
| FR (1) | FR2926023B1 (ja) |
| PL (1) | PL2240197T3 (ja) |
| PT (1) | PT2240197E (ja) |
| WO (1) | WO2009106767A2 (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2941230B1 (fr) * | 2009-01-19 | 2011-03-18 | Centre Nat Rech Scient | Polypeptides d'adressage specifique a des cellules-cibles d'otx2 |
| PL3352777T3 (pl) | 2015-09-23 | 2022-02-07 | Centre National De La Recherche Scientifique | Engrailed do stosowania w leczeniu uszkodzenia dna u pacjentów cierpiących na chorobę parkinsona |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002325571A (ja) * | 2001-04-27 | 2002-11-12 | Purotekku:Kk | 網膜の分化誘導方法 |
| CN1747744B (zh) * | 2003-02-03 | 2011-07-27 | 独立行政法人科学技术振兴机构 | 使用otx2基因再生和新生视网膜感光细胞 |
| US7541186B2 (en) * | 2006-02-22 | 2009-06-02 | University Of Washington | Method of generating human retinal progenitors from embryonic stem cells |
| US9243226B2 (en) * | 2007-02-23 | 2016-01-26 | University Of Central Florida Research Foundation, Inc. | Biasing of cells toward retinal, corneal or lens development |
| FR2941230B1 (fr) * | 2009-01-19 | 2011-03-18 | Centre Nat Rech Scient | Polypeptides d'adressage specifique a des cellules-cibles d'otx2 |
-
2008
- 2008-01-09 FR FR0800110A patent/FR2926023B1/fr not_active Expired - Fee Related
-
2009
- 2009-01-09 CA CA2711866A patent/CA2711866C/fr active Active
- 2009-01-09 EP EP09715010.6A patent/EP2240197B1/fr active Active
- 2009-01-09 DK DK09715010.6T patent/DK2240197T3/en active
- 2009-01-09 US US12/812,139 patent/US10722554B2/en active Active
- 2009-01-09 JP JP2010541823A patent/JP5851692B2/ja active Active
- 2009-01-09 WO PCT/FR2009/000031 patent/WO2009106767A2/fr active Application Filing
- 2009-01-09 PT PT97150106T patent/PT2240197E/pt unknown
- 2009-01-09 PL PL09715010T patent/PL2240197T3/pl unknown
- 2009-01-09 ES ES09715010.6T patent/ES2542518T3/es active Active
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