JP2011183043A - Medicine introducing sheet and kit - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a medicine introducing sheet and a kit thereof which can be inserted in an adjacent surface of the interdental part easily, and can contain enough amounts of medicine in a caries portion. <P>SOLUTION: The medicine introducing kit comprises a plate-like board sheet 11 which can be inserted in interdental part and an elastically deformable functional layer 12 which is formed at least either on the surface or the rear surface of the board sheet 11. The functional layer 12 has the medicine introducing sheet 1 containing medicine to be stuck on teeth. Additionally, it has such the medicine introducing sheet 1 and a holding part for maintaining the medicine introducing sheet 1 which is arranged at least on one end of the medicine introducing sheet 1. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to a drug introduction sheet and a kit including the same.

  Conventionally, as a means for diagnosing the caries portion in the oral cavity, a method is known in which a strip provided with a layer impregnated with an oral health care substance is inserted into the oral cavity (see, for example, Patent Document 1). The strip is provided with a fixture at approximately the same interval as the tooth-to-tooth gap, and the fixture fits into the tooth-to-tooth gap. The strip is also softened and stretchable by the action of moisture, chemicals or enzymes in the oral cavity.

  Conventionally, a method of inserting a sheet that absorbs moisture contained in initial caries into the oral cavity is known (see, for example, Patent Document 2). This sheet is formed to be slightly thinner so that the gap between adjacent teeth can be expanded with a ring or the like, and a water absorbing sheet can be inserted into the gap, and further, it can be easily inserted by an insertion guide or the like. .

  In addition, conventionally, a method of expanding a space between teeth by inserting a spacer such as a wedge and guiding a fluorescent substance to a caries portion between teeth is known (for example, see Patent Document 3). In this method, the fluorescent material is guided to the caries portion by a metal piece, a plastic piece, a paper piece, and a syringe.

Special table 2004-538085 gazette Japanese Patent Laid-Open No. 11-14624 US Patent Application Publication No. 2008/0038686

  Patent Document 1 describes that oral health care is released to the surface of a tooth by a strip provided with an oral health care substance layer. Further, it is described that an adhesive function can be obtained by fitting fixed portions provided at regular intervals between teeth. However, the introduction of a drug between teeth is not described, and the fluorescent substance is not mentioned.

  Patent Document 2 describes that a sheet is inserted between teeth by using a moisture-absorbing sheet capable of detecting a minute amount of moisture contained in the initial caries and an interdental expansion ring. However, since the strength of the sheet itself is weak, it is not possible to insert the sheet into the adjacent surface unless the distance between the teeth is expanded, and there is a disadvantage that the work is complicated.

  In addition, according to the technique disclosed in Patent Document 3, since a sheet having a certain thickness such as a plastic piece or a metal piece is inserted into the adjacent surface, it is possible to closely contact the drug over a wide range of the adjacent surface. There is an inconvenience that it is difficult.

  That is, according to the techniques disclosed in Patent Documents 1 to 3, no specific means for guiding a sufficient amount of drug to the caries part with respect to the adjacent caries part has been shown.

  This invention is made | formed in view of the said situation, and it aims at providing the chemical | medical agent introduction sheet | seat which can hold | maintain a sufficient quantity of chemical | medical agent to a caries part on the adjacent surface between teeth, and a kit provided with the same.

In order to achieve the above object, the present invention employs the following means.
A first aspect of the present invention includes a plate-like substrate sheet that can be inserted between teeth, and a functional layer that is formed on at least one of the front surface and the back surface of the substrate sheet and can be elastically deformed. Is a drug introduction sheet in which the drug attached to the teeth is absorbed.

  According to the first aspect of the present invention, when the drug introduction sheet is inserted between the teeth, the functional layer formed on at least one of the front surface and the back surface of the substrate sheet is elastically deformed. And after inserting a chemical | medical agent introduction sheet between teeth, a functional layer is pressed on the adjacent surface of a tooth | gear with the elastic force. Thereby, the medicine contained in the functional layer can be held while adhering to the adjacent surfaces of the teeth, and a sufficient amount of the medicine can be applied to the caries portion formed on the adjacent surfaces of the teeth over a desired time. Can be attached.

In the first aspect, the total thickness of the substrate sheet and the functional layer may be within 50 μm.
By making the total thickness of the substrate sheet and the functional layer within 50 μm, the workability when inserting the drug introduction sheet between the teeth can be improved.

In the first aspect, the functional layer may be made of a polymer material.
By configuring the functional layer with a polymer material, the water absorption of the drug can be improved, and when the drug introduction sheet is inserted between the teeth, a sufficient amount for the caries portion formed on the adjacent surface between the teeth The drug can be induced.

Said 1st aspect WHEREIN: The said functional layer is good also as being comprised from the porous material.
By configuring the functional layer with a porous material, it is possible to improve the water absorption of the drug, and when the drug introduction sheet is inserted between the teeth, a sufficient amount for the caries portion formed on the adjacent surface between the teeth The drug can be induced.

In the first aspect, the functional layer may expand by being impregnated with a liquid.
In this way, when the drug introduction sheet is inserted between the teeth, the functional layer is expanded by moisture such as saliva in the oral cavity, and the force for pressing the functional layer against the adjacent surface between the teeth can be increased. It is possible to improve the holding force when the drug introduction sheet is inserted between the teeth.

In the first aspect, the functional layer may absorb a temperature-responsive polymer aqueous solution that changes from a sol state to a gel state at a predetermined temperature.
Thus, when the drug introduction sheet is inserted between the teeth, the temperature-responsive polymer aqueous solution absorbed in the functional layer at, for example, the oral cavity temperature (35 ° C. to 37 ° C.) is changed from the sol state to the gel state. Can be changed. Thereby, a chemical | medical agent can be made to stay in the caries part formed in the adjacent surface between teeth, and a sufficient quantity of chemical | medical agents can be made to adhere to a caries part over a long time.

Said 1st aspect WHEREIN: The said functional layer is good also as being formed in the center part of the said board | substrate sheet | seat.
By doing in this way, when a chemical | medical agent introduction sheet is inserted between teeth, a functional layer can be made to contact the caries part between teeth reliably.

Said 1st aspect WHEREIN: The said chemical | medical agent is good also as being a fluorescent chemical | medical agent which adheres specifically to a caries part.
Thereby, a fluorescent agent is made to adhere to the caries part between teeth, and the observation and diagnosis can be easily performed.

A second aspect of the present invention is a drug introduction kit comprising the above-described drug introduction sheet and a holding portion that is provided at at least one end of the drug introduction sheet and holds the drug introduction sheet.
According to such a drug introduction kit, it is possible to insert the drug introduction sheet between the teeth in the oral cavity by grasping the holding portion, and to improve the workability.

Said 2nd aspect WHEREIN: The said holding | maintenance part is good also as being provided in the said chemical | medical agent introduction sheet so that attachment or detachment is possible.
By doing in this way, after inserting a medicine introduction sheet between teeth in an oral cavity, a holding part can be removed from a medicine introduction sheet. Thereby, while ensuring the space in an oral cavity, the holding | maintenance part can be combined with a some chemical | medical agent introduction sheet, and the manufacturing cost can be reduced.

Said 2nd aspect WHEREIN: The said holding | maintenance part is good also as providing the storage part which stores the said chemical | medical agent.
In this way, after inserting the drug introduction sheet between the teeth in the oral cavity, the drug stored in the storage part can be gradually released to the caries part between the teeth, and there is a sufficient amount in the caries part. Can be applied over a long period of time. For example, when a temperature-responsive polymer aqueous solution is used for a drug, the drug is released after the drug introduction sheet is inserted between the teeth, so that the temperature responsiveness can be obtained while the drug introduction sheet is inserted between the teeth. It can prevent that polymer aqueous solution gelatinizes.

  ADVANTAGE OF THE INVENTION According to this invention, there exists an effect that it can be easily inserted in the adjacent surface between teeth and a sufficient quantity of chemical | medical agents can be hold | maintained in a caries part.

It is a perspective view of the medicine introduction sheet concerning a 1st embodiment of the present invention. It is a cross-sectional view of the medicine introduction sheet of FIG. It is a figure explaining the state which the functional layer of the chemical | medical agent introduction sheet | seat of FIG. 1 expand | swells. It is a figure explaining the state which inserted the chemical | medical agent introduction sheet | seat of FIG. 1 between teeth. It is a figure explaining the state which the chemical | medical agent introduction sheet | seat of FIG. 4 expanded. It is a perspective view of the medicine introduction sheet concerning a 2nd embodiment of the present invention. It is a figure explaining the effect | action of the chemical | medical agent introduction sheet | seat of FIG. It is a figure explaining the state which inserts the chemical | medical agent introduction sheet | seat of FIG. 6 between teeth. It is a figure explaining the state which the chemical | medical agent introduction sheet | seat of FIG. 8 expanded. It is a figure explaining the effect | action of the chemical | medical agent introduction sheet | seat of FIG. It is the elements on larger scale of the A section of FIG. The chemical | medical agent introduction sheet | seat unit which concerns on the 3rd Embodiment of this invention is shown, (a) is a perspective view, (b) is a cross-sectional view. The holding | maintenance part which concerns on the 3rd Embodiment of this invention is shown, (a) is a perspective view, (b) is a cross-sectional view. It is a cross-sectional view of the medicine introduction kit according to the third embodiment of the present invention. It is a perspective view which shows the example of application of the chemical | medical agent introduction kit of FIG. It is a top view in the oral cavity which inserts the chemical | medical agent introduction sheet unit of FIG. It is a figure which shows the state which fits the attachment part and holding | maintenance part of FIG. It is a figure which shows the state which inserts the chemical | medical agent introduction kit of FIG. 17 between teeth. It is a figure which shows the state which removes a holding | maintenance part from the attachment part of FIG. It is a side view of the medicine introduction kit concerning the 1st modification. The chemical | medical agent introduction kit which concerns on a 2nd modification is shown, (a) is a perspective view, (b) is a cross-sectional view. It is a side view of the medicine introduction kit concerning the 3rd modification. It is a figure explaining the state at the time of the chemical | medical agent injection | pouring of the chemical | medical agent introduction kit of FIG. It is a figure explaining the state at the time of the chemical | medical agent supply to the functional layer of the chemical | medical agent introduction kit of FIG.

[First Embodiment]
Hereinafter, the medicine introduction sheet 1 according to the first embodiment of the present invention will be described with reference to the drawings.
As shown in FIG. 1, the drug introduction sheet 1 according to the present embodiment is inserted between teeth 35 and teeth 36 (interdental), so that the drug is formed on the caries portion formed on the adjacent surface between the teeth. It is a sheet to introduce. The drug introduction sheet 1 has, for example, a size of about 10 mm long × 20 mm wide × 50 μm thick so that it can be inserted between teeth. Here, workability at the time of inserting the medicine introduction sheet 1 between teeth can be improved by setting the thickness to 50 μm or less.

As shown in FIG. 2, the drug introduction sheet 1 includes a plate-like substrate sheet 11 that can be inserted between teeth, and a functional layer 12 formed on the front surface and the back surface of the substrate sheet 11.
The substrate sheet 11 is a plate-like sheet having a predetermined strength so that it can be inserted between teeth, and functional layers 12 are formed on both sides thereof. Specifically, the substrate sheet 11 is made of polyethylene, polyolefin film, polyester, polycarbonate film, polystyrene film, or the like.

The functional layer 12 has water absorption and elasticity, and the drug attached to the teeth is absorbed.
The functional layer 12 is made of, for example, a polymer material. By constituting the functional layer 12 with a polymer material, the water absorption of the drug can be improved, and when the drug introduction sheet 1 is inserted between the teeth, it is sufficient for the caries portion formed on the adjacent surface between the teeth. A large amount of drug can be induced.

  Further, as shown in FIG. 3, the functional layer 12 has a property of expanding when impregnated with a liquid. Thereby, when the medicine introduction sheet 1 is inserted between the teeth, the functional layer 12 is expanded by moisture such as saliva in the oral cavity, and the force for pressing the functional layer 12 against the adjacent surface between the teeth can be increased. The holding power when the drug introduction sheet 1 is inserted between the teeth can be improved.

  Specifically, the drug absorbed in the functional layer 12 is a pigment composed of HiLyte Fluor, Qdot, Indocyanine Green (ICG), Doxorubicin, Riboflavin, Chlorophyll, Porphyrin, Osteosense, Gold nanoshell, Bacteriochlorophyll, and at least polyacrylic acid , Methacrylic acid, 2-acryloylethanesulfonic acid and other polymer materials, hyaluronic acid, carrageenan, carboxymellitic cellulose sodium salt, alginic acid polysaccharides, and proteins such as collagen and gelatin. It adheres specifically to.

The effect | action at the time of inserting the chemical | medical agent introduction sheet 1 which has the said structure between teeth is demonstrated.
As shown in FIG. 4, when the drug introduction sheet 1 is inserted between the teeth 35 and the teeth 36 (between teeth), the functional layer 12 formed on the front surface and the back surface of the substrate sheet 11 is elastically deformed. Therefore, the medicine introduction sheet 1 can be easily inserted between the teeth without using a device such as an interdental expansion ring that expands the spaces between the teeth.

  And after inserting the medicine introduction sheet 1 between the teeth, the functional layer 12 is pressed against the adjacent surfaces of the teeth 35 and the teeth 36 by its elastic force. Further, as the functional layer 12 absorbs moisture such as saliva in the oral cavity, the polymer material of the functional layer 12 expands as shown in FIG. 5, and the drug introduction sheet fills the gap between the teeth 35 and 36. 1 spreads.

  Thereby, the chemical | medical agent contained in the functional layer 12 can be hold | maintained, making it adhere to the adjacent surface of the tooth | gear 35 and the tooth | gear 36. FIG. In this state, the dye contained in the functional layer 12 is dissolved in water together with the polymer material to form a dye aqueous solution, and this dye aqueous solution is released gradually, so that the entire surface adjacent to the teeth 35 and the teeth 36 is obtained. And it becomes possible to introduce | transduce a pigment | dye uniformly. As a result, a sufficient amount of drug can be adhered to the caries portion formed on the adjacent surfaces of the teeth 35 and 36 over a desired time.

Moreover, when the functional layer 12 is formed in the center portion of the substrate sheet 11, the functional layer 12 can be reliably brought into contact with the caries portion 17 between the teeth when the drug introduction sheet 1 is inserted between the teeth. .
In the present embodiment, it has been described that the functional layer 12 expands by absorbing moisture such as saliva in the oral cavity. However, in order to expand the functional layer 12, water or an alcohol aqueous solution is used after being inserted between teeth. It is good also as spreading on the introduction sheet 1.

[Second Embodiment]
Next, the medicine introduction sheet 2 according to the second embodiment of the present invention will be described with reference to the drawings. In the description of the present embodiment, description of points that are common to the drug introduction sheet 1 according to the first embodiment will be omitted, and different points will be mainly described.
As shown in FIG. 6, the drug introduction sheet 2 according to this embodiment includes a plate-like substrate sheet 11 that can be inserted between teeth, and a functional layer 12 that is formed (adhered) on the front and back surfaces of the substrate sheet 11. It has.

The functional layer 12 is made of a sponge-like porous material having a large number of pores and has water absorption and elasticity. This porous material has a thickness of about 1 to 3 mm, for example.
The functional layer 12 holds a temperature-responsive polymer aqueous solution 17 in which a fluorescent agent 15 that reacts specifically with the caries portion 7 and a temperature-responsive polymer 16 that changes from a sol state to a gel state at a predetermined temperature are dissolved. Yes.

  The temperature-responsive polymer aqueous solution 17 includes, for example, a dye composed of HylyteFluor, Qdot, IndocyanineGreen, Doxorubicin, Riboflavin, Chlorophyll, Porphyrin, Osteosense, Gold nanoshell, and the like. , Alkyl-PEO block surfactants, Poly (vinyl methyl ether), Poly (osyethelene vinyl ether), Hydrosypropyl acrylate, Hydroxypropyl methylcellulose, Hydroxypropyl cellulose, Methylcellulose, Poly (vinyl alcohol), Poly (N-substituted acrylamides), Poly (N- It is an aqueous solution containing a polymer material having temperature responsiveness such as vinyl pyrrolidone), Poly (ethyl oxazoline), Poly (N-vinylisobutylamide), Poly (2-carboxyisopropylacrylamide), Poly (methacrylic acid).

  The temperature-responsive polymer aqueous solution 17 has a transition temperature at which it transitions from a sol state to a gel state at 35 ° C. to 37 ° C., for example. Thereby, as shown in FIG. 7, the temperature-responsive polymer aqueous solution 17 is heated to 35 ° C. to 37 ° C., so that the temperature-responsive polymer 16 gels and the fluorescent agent 15 is gradually released together with water. It is like that.

The effect | action at the time of inserting the chemical | medical agent introduction sheet 2 which has the said structure between teeth is demonstrated.
As shown in FIG. 8, the caries portion 7 is formed on the surface of the tooth 36 adjacent to the tooth 35.
When the drug introduction sheet 2 is inserted between the teeth, the functional layer 12 bonded to the front and back surfaces of the substrate sheet 11 is elastically deformed. That is, the drug introduction sheet 2 can be easily inserted between the teeth without using a device such as an interdental expansion ring that expands the spaces between the teeth.

  And after inserting the chemical | medical agent introduction sheet 2 between teeth, as shown in FIG. 9, the functional layer 12 is pressed on the adjacent surface of the tooth | gear 35 and the tooth | gear 36 with the elastic force. Thereby, the fluorescent agent 15 included in the functional layer 12 can be held while being attached to the adjacent surfaces of the teeth 35 and the teeth 36.

  In this state, the fluorescent agent 15 contained in the functional layer 12 together with the polymer material is dissolved in water to become a dye aqueous solution, and this dye aqueous solution is gradually released. As shown in FIG. It becomes possible to introduce the fluorescent agent 15 uniformly over the entire adjacent surfaces of the teeth 35 and the teeth 36.

  Further, the temperature-responsive polymer 16 that has penetrated into the caries portion 7 is warmed by the intraoral temperature and reaches the transition temperature. The temperature-responsive polymer aqueous solution 17 that has reached the transition temperature is gelled, and the fluorescent agent 15 in the temperature-responsive polymer aqueous solution 17 is slowly released to the caries part 7 together with water. Further, as shown in FIG. 11, the temperature-responsive polymer 16 is heated and gelled in the caries part 7 by the temperature in the oral cavity, thereby allowing the fluorescent agent 15 to remain in the caries part 7 for a long time. Can do. Thereby, a sufficient amount of the fluorescent agent 15 can be adhered to the caries portion 7 for a long time.

  Moreover, the chemical | medical agent introduce | transduced into the caries part 7 is made into the fluorescent agent 15 which adheres specifically to the caries part 7, By attaching the fluorescent agent 15 to the caries part 7 between teeth, the observation and diagnosis are performed easily. be able to.

[Third Embodiment]
Next, a drug introduction kit 3 according to a third embodiment of the present invention will be described with reference to the drawings. In the description of the present embodiment, description of points that are common to the drug introduction sheets 1 and 2 according to the above-described embodiments is omitted, and different points are mainly described.

  The drug introduction kit 3 according to the present embodiment includes the drug introduction sheet 1 according to the first embodiment and a holding unit 22 that holds the drug introduction sheet 1. In addition, although this embodiment demonstrates the example using the chemical | medical agent introduction sheet 1 which concerns on 1st Embodiment as an example, even if it uses the chemical | medical agent introduction sheet 2 which concerns on 2nd Embodiment, the same effect is obtained. be able to.

The drug introduction kit 3 according to this embodiment includes a drug introduction sheet unit 20 shown in FIGS. 12 (a) and 12 (b), and a holding portion 22 shown in FIGS. 13 (a) and 13 (b). ing.
As shown in FIGS. 12A and 12B, the drug introduction sheet unit 20 is provided at the drug introduction sheet 1 according to the first embodiment and the end of the drug introduction sheet 1, and the holding unit 22. And a fitting portion 21 to be fitted.

The attachment portion 21 is composed of two rectangular plates, and is fixed to the end of the drug introduction sheet 1 by sandwiching and bonding the substrate sheet 11 portion of the drug introduction sheet 1 with the two plates. Yes.
The attachment portion 21 is a square member extending in the longitudinal direction of the drug introduction sheet 1 as shown in FIG. 12A, and has a rectangular cross section as shown in FIG. 12B.

As shown in FIG. 13A, the holding part 22 is a square member longer than the attachment part 21, and an operator can have an end part.
As shown in FIG. 13B, the holding portion 22 is formed with a groove 25 that extends in the longitudinal direction of the holding portion 22 and has a cross-sectional shape larger than the cross-sectional shape of the attachment portion 21. On both side surfaces of the groove 25, fitting portions 26 that extend in a direction orthogonal to the longitudinal direction of the holding portion 22 and are fitted with the attachment portion 21 are provided.

By having the above configuration, as shown in FIG. 14, the attachment portion 21 provided on the drug introduction sheet 1 is inserted into the groove 25 of the holding portion 22, thereby attaching the attachment portion 21 to the fitting portion 26 of the holding portion 22. Can be fitted.
Moreover, the holding part 22 can be removed from the attaching part 21 by sliding the holding part 22 in the longitudinal direction with respect to the attaching part 21 from this state.

The operation of the drug introduction kit 3 having the above configuration will be described.
Here, as shown in FIG. 15, a case where twelve drug introduction sheet units 20 are accommodated in the case 28 will be described as an example. In this example, the medicine introduction sheet units 20 are taken out one by one from the case 28 by the holding portion 22, and the taken out medicine introduction sheet units 20 are respectively inserted between the teeth in the oral cavity as shown in FIG.

  In this case, first, as shown in FIG. 17, the holding portion 22 is operated in the longitudinal direction of the drug introduction sheet 1 to insert the attachment portion 21 of the drug introduction sheet unit 20 into the groove 25 of the holding portion 22. The attachment part 21 and the holding part 22 are fitted.

Next, as shown in FIG. 18, the drug introduction sheet 1 is inserted between the tooth 35 and the tooth 36 in the oral cavity with the end of the holding part 22.
After inserting the drug introduction sheet 1 between the teeth, as shown in FIG. 19, the holding part 22 is operated in the longitudinal direction of the drug introduction sheet 1 (frontward as viewed from the user) to attach the holding part 22 to the attachment part 21. Remove from.

As described above, according to the drug introduction kit 3 according to the present embodiment, the drug introduction sheet 1 can be inserted between the teeth in the oral cavity by grasping the holding portion 22 and the workability can be improved. .
Further, by making the holding part 22 detachable from the medicine introduction sheet unit 20, the holding part 22 can be detached from the medicine introduction sheet 1 after the medicine introduction sheet 1 is inserted between teeth in the oral cavity. Thereby, while ensuring the space in an oral cavity, the holding | maintenance part 22 can be shared by the some chemical | medical agent introduction sheet | seat 1, and the manufacturing cost can be reduced.

  The attachment portion 21 only needs to be able to be fitted to the holding portion 22, may have a cross-sectional shape with four corners chamfered, and has a polygonal shape such as a triangle or a pentagon. Also good. Furthermore, the attachment part 21 does not necessarily extend over the entire longitudinal direction of the drug introduction sheet 1, and may be provided, for example, at two longitudinal ends of the drug introduction sheet 1.

[First Modification]
Hereinafter, the drug introduction kit 4 according to a first modification of the present embodiment will be described.
As shown in FIG. 20, the drug introduction kit 4 according to the present modification has a taper shape in which the attachment portion 21 of the drug introduction sheet unit 20 has a transverse cross section that decreases in the longitudinal direction of the drug introduction sheet 1. Yes.

Further, the groove 25 provided in the holding portion 22 is formed so as to have a smaller cross section from the distal end portion toward the proximal end portion in accordance with the shape of the mounting portion 21.
By forming the groove 25 in this way, it is possible to easily perform the detachment operation between the holding portion 22 and the drug introduction sheet unit 20, particularly the operation of removing the holding portion 22 from the drug introduction sheet unit 20. Can be improved.

[Second Modification]
The drug introduction kit according to the second modification of the present embodiment will be described below.
As shown in FIGS. 21 (a) and 21 (b), the drug introduction kit according to this modified example has a circular cross-sectional shape of the attachment portion 21 of the drug introduction sheet unit 20, and radially outwards. A protruding portion 31 that protrudes is provided.
Moreover, the groove | channel 25 provided in the holding | maintenance part 22 is formed with the groove | channel 32 with which the projection part 31 fits according to the shape of the attachment part 21. FIG.

  By forming the attachment portion 21 (protrusion portion 31) and the groove 32 in this way, when the attachment portion 21 is inserted into the groove 25 of the holding portion 22, the protrusion portion 31 is against the holding portion 22 with the drug introduction sheet. It functions as a locking means for preventing the unit 20 from rotating around the central axis of the mounting portion 21.

  According to the medicine introduction kit according to the present modification, the attachment portion 21 has a circular cross-sectional shape. Therefore, when the medicine introduction sheet unit 20 is inserted into the adjacent surface between the teeth, the attachment portion 21 is the oral cavity. Injuries can be prevented when touching the inner soft tissue, and the pain at that time can be alleviated.

[Third Modification]
Hereinafter, a drug introduction kit 6 according to a third modification of the present embodiment will be described.
As shown in FIG. 22, in the drug introduction kit 6 according to this modification, the holding unit 22 is provided with a storage unit 41 that stores the drug.

The holding unit 22 is provided with a cavity 42 that communicates with the functional layer 12 and the storage unit 41 and supplies the drug stored in the storage unit 41 to the functional layer 12 of the drug introduction sheet 1.
In addition, a heat insulating material 43 that prevents the worker's body temperature from being transmitted to the medicine in the storage unit 41 is provided around the storage unit 41.

The operation of the drug introduction kit 6 having the above configuration will be described.
As shown in FIG. 23, when the operator holds the holding part 22, the medicine sealed inside the storage part 41 is pushed out, and the medicine is sent to the cavity part 42.
Then, as shown in FIG. 24, the medicine sent through the cavity 42 is supplied to the functional layer 12 of the medicine introduction sheet 1, and the medicine infiltrates into the functional layer 12.

  As described above, according to the drug introduction kit 6 according to the present modification, after the drug introduction sheet 1 is inserted between the teeth in the oral cavity, the drug stored in the storage unit 41 is transferred to the caries part between the teeth. Slow release is possible, and a sufficient amount of drug can be adhered to the caries portion over a long period of time. For example, when using a temperature-responsive polymer aqueous solution for a drug, the drug is released after the drug introduction sheet 1 is inserted between the teeth, so that the temperature is increased while the drug introduction sheet 1 is inserted between the teeth. It is possible to prevent the responsive polymer aqueous solution from gelling.

As mentioned above, although embodiment of this invention was explained in full detail with reference to drawings, the specific structure is not restricted to this embodiment, The design change etc. of the range which does not deviate from the summary of this invention are included.
For example, in each embodiment, the functional layer 12 has been described as being formed on the front surface and the back surface of the substrate sheet 11, but may be formed only on one surface of the substrate sheet 11.

1, 2 Drug introduction sheet 3, 4, 6 Drug introduction kit 7 Caries section 11 Substrate sheet 12 Functional layer 15 Fluorescent drug 16 Temperature responsive polymer 17 Temperature responsive polymer aqueous solution 20 Drug introduction sheet unit 21 Mounting section 22 Holding section 25 31 Projection part 41 Storage part 42 Cavity part 43 Heat insulation material

Claims (11)

A plate-like substrate sheet that can be inserted between teeth;
Formed on at least one of the front surface and the back surface of the substrate sheet, and comprising an elastically deformable functional layer,
The functional layer is a drug introduction sheet in which a drug attached to teeth is absorbed.   The drug introduction sheet according to claim 1, wherein the total thickness of the substrate sheet and the functional layer is within 50 μm.   The drug introduction sheet according to claim 1, wherein the functional layer is made of a polymer material.   The drug introduction sheet according to claim 1, wherein the functional layer is made of a porous material.   The drug introduction sheet according to claim 1, wherein the functional layer expands by being impregnated with a liquid.   The drug introduction sheet according to claim 1, wherein the functional layer absorbs a temperature-responsive polymer aqueous solution that changes from a sol state to a gel state at a predetermined temperature.   The drug introduction sheet according to claim 1, wherein the functional layer is formed at a central portion of the substrate sheet.   The drug introduction sheet according to claim 1, wherein the drug is a fluorescent drug that specifically adheres to a caries portion. The drug introduction sheet according to any one of claims 1 to 8,
A drug introduction kit provided with a holding part that is provided at at least one end of the drug introduction sheet and holds the drug introduction sheet.   The drug introduction kit according to claim 9, wherein the holding unit is detachably provided on the drug introduction sheet.   The medicine introduction kit according to claim 9, wherein the holding part is provided with a storage part for storing the medicine.

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