JP2011160840A - Clean system for periosteal regenerative medicine - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a clean system for periosteal regenerative medicine, which saves space and is excellent in handleability. <P>SOLUTION: The clean system for the periosteal regenerative medicine includes: a clean bench body; an incubator storage case provided on one side of the clean bench; an incubator installed in the incubator storage case, the incubator storage case and the incubator being disposed obliquely forward relative to the wall surface of the clean bench. A pass box with a germicidal lamp can be provided on the wall of the clean bench. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to a clean system related to periosteum regenerative medicine, and particularly to a clean system for periosteum regenerative medicine of a clean bench provided with a pass box and an incubator.

  In the regenerative medicine field, “Regenerative medicine field (design guidelines for human cell culture processing equipment) development guidelines 2008” (Ministry of Economy, Trade and Industry) was established in 2008. Among them, prevention of contamination and assurance of sterility of culture system (regulation of cleanliness environment, decontamination treatment, etc.) were stipulated. In this way, the environment where regenerative medicine is performed requires facilities that ensure a certain degree of cleanliness, prevent cross-contamination, and can be decontaminated.

  In performing periosteal regenerative medicine, equipment that clears the above regenerative medicine guidelines is necessary. A system that is easy to introduce is required. For example, it is easy to install in an existing building, has a small installation space, and is easy to use.

A facility that meets the guidelines is a high-performance facility called a cell processing center (CPC), but there are only a few institutions that can be introduced at a high price, making it unsuitable for periosteal regenerative medicine. Considering facilities that can be installed in general medical institutions and hospitals and that can satisfy the guidelines, an ISO class 5 simple clean room is installed, and a clean bench, incubator, and decontamination equipment are installed in this room. . However, if these are simply placed, the installation area is large, and even for ease of use, the sample treated with the clean bench is taken out of the clean bench and stored in the incubator, but there is a possibility of contamination due to disturbance even in the clean room. . Also, operations and work are complicated.
In order to introduce equipment that performs decontamination of equipment and workpieces, implementation of periosteum regeneration work, storage in incubator, removal, etc. while maintaining cleanliness ISO class 5 in a limited hospital space A large space is required to install a clean room with boxes, and to place clean benches and incubators.

An object of the present invention is to provide a clean system for regenerative medicine that is free from the above-mentioned problems and that is space-saving and excellent in usability.
Since there is no prior art document information to be described, patent documents and the like are not described.

In order to achieve the above object, the present invention has an incubator placed diagonally forward in the clean bench cleaning work table that creates a clean environment, and a pass box for introducing equipment and samples into the clean bench can be attached and detached. It shall be attached to the structure.
By integrating the pass box, clean bench, and incubator so that equipment and workpieces can be handled inside this system, and by placing the incubator diagonally toward the front, the space-saving exhaust section and work platform can be located inside. A wind speed sensor is provided to calculate the inflow wind speed.

  The present invention has a structure in which an incubator is disposed obliquely forward in a clean bench of a clean bench that creates a clean environment, and a pass box for introducing equipment and workpieces into the clean bench can be detachably attached. The installation space is small, and it is easy to introduce, and there is an effect that a system with good workability can be provided.

The front view of the clean system for periosteum regenerative medicine of the present invention. Sectional drawing of the clean bench of the clean system for periosteum regenerative medicine of this invention. The front view and side view of an incubator. FIG. 2 is a top sectional view of the periosteal regenerative medical clean system of FIG. 1 according to the present invention.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings.

  FIG. 1 shows a front view of a clean system for periosteal regenerative medicine of the present invention. In FIG. 1, reference numeral 1 denotes a clean bench body, and 2 denotes an incubator storage case provided on the right side of the clean bench body 1. Reference numeral 3 denotes an incubator, which is shown in detail in FIG. 3 and will be described later. FIG. 4 is a top view of the clean system. FIG. 4 shows the positional relationship between the clean system and the worker 7.

  First, the clean bench 1 of the present invention will be described with reference to FIG. FIG. 2 shows a cross-sectional view of the clean bench 1. In FIG. 2, the left side is the front surface of the clean bench, and the right side is the back surface of the clean bench. Reference numeral 12 denotes a fan, 13 denotes a HEPA filter, 14 denotes a HEPA filter for exhausting air to the outside of the clean bench 1, and 15 denotes a work chamber. Reference numeral 16 denotes clean air blown from the upper part of the work chamber 15, reference numeral 17 denotes a front shutter provided on the working side, and reference numeral 22 denotes a front opening for the operator 7 to insert his / her hand. .

  Reference numeral 20 denotes an exhaust port for circulating air provided in the lower part on the front side of the work chamber 15, and 18 denotes a circulation passage provided in the lower part of the bottom of the work chamber. Reference numeral 19 denotes a circulation passage provided on the back side of the back side wall of the work chamber 15, and 21 denotes an exhaust port provided on the lower back side of the work chamber 15.

  In the configuration of FIG. 2, the air flow of the clean bench 1 will be described.

  When the fan 12 provided at the upper portion of the clean bench 1 rotates, the air is filtered through the HEPA filter 13 for supplying air, and the clean air 16 is blown out into the work chamber 15 from above.

  An operator works by putting his / her hand through the front opening 22 below the front shutter 17 under the clean air blown into the work chamber 15. Air contaminated during work in the work chamber is exhausted from the exhaust port 20 in the lower front portion of the work chamber 15 and sent to the circulation passage 18 below the bottom of the work chamber 15. It is sent to the upper part of the clean bench 1 through the circulation passage 19.

  Further, the air in the work chamber is also discharged from the exhaust port 21 provided in the lower portion on the back side of the work chamber 15 and sent to the upper portion of the clean bench 1 through the circulation passage 19 on the back surface of the work chamber.

  In the upper part of the clean bench 1, the dust is filtered and discharged to the outside of the clean bench 1 through the discharge HEPA filter 14.

  Next, the incubator 4 will be described with reference to FIG.

  An incubator is a device that holds samples such as bacteria to be cultured at a constant temperature, and is called a thermostat or a thermostat.

  Further, as shown in FIG. 3, the incubator 3 is a drawer 40 for storing and taking out a sample to be cultured, etc., and temperature control is performed using a microcomputer or the like in order to maintain the temperature in the drawer with high accuracy. A controller 30 is provided.

Further, the incubator 3 is provided with an incubator storage case 2 on the right (or left) wall of the clean bench 1 as shown in FIG. 1, and the incubator 3 is installed in this place.
The storage case 2 and the incubator 3 of the incubator are arranged obliquely forward so that the operator 7 can easily take out the sample and the like. The oblique forward angle is in the range of 30 degrees to 60 degrees, and around 45 degrees is optimal. Furthermore, it arrange | positions so that the hand of the operator 7 may reach from the opening part 22 of the front shutter lower part of a clean bench.

  By installing such an incubator in the work room of the clean bench, it is possible to prevent a culture sample or the like from leaking outside the clean bench.

  Next, the pass box 4 installed on the left side of the clean bench 1 in FIG. 1 will be described.

  The pass box 4 is used to prevent the equipment used in the work room 15 of the clean bench 1 or the culture sample from being directly supplied to or taken out of the work room. Is to do.

  Therefore, the pass box 4 is attached to the wall surface of the clean bench 1 so that the door 9 of the pass box can be opened and closed from the work chamber 15. Further, the door 8 of the pass box 4 outside the clean bench can be opened and closed from the outside, and the sample 5 in the pass box 4 can be taken out from the outside of the clean bench working chamber.

  Further, the pass box 4 adopts an interlock system, that is, in the doors 8 and 9 in FIG. 3, when the door 8 is open, the door 9 is closed, and when the door 9 is open. The door 8 is closed and serves as a mechanism for preventing the inflow of air around the clean bench 1.

  Reference numerals 10 and 11 in FIG. 1 denote germicidal lamps provided on the door 8.

  Further, the pass box 4 itself can be removed, and the opening of the clean bench 1 after being removed can be closed with a cover.

  According to such a configuration, it is possible to perform treatments neatly according to the procedure of periosteum regeneration, and it is possible to construct a system that saves space as equipment.

DESCRIPTION OF SYMBOLS 1 ... Clean system main body 2 for regenerative medicine of this invention ... Incubator storage case 3 ... Incubator 4 ... Pass box 5 ... Apparatus and sample 6 ... Work bench room 7 ... Worker 8 ... Pass box front door 9 ... Pass box clean bench side door
10 ... germicidal lamp (top)
11 ... germicidal lamp (bottom)

Claims (2)

  A clean bench body and an incubator storage case on one side of the clean bench, the incubator is installed in the incubator storage case, and the incubator storage case and the incubator are placed in front of the wall of the clean bench obliquely. Medical clean system.   The clean system for regenerative medicine according to claim 1, comprising a pass box having a germicidal lamp provided on a wall of the clean bench.

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