JP2011083403A - Cognitive function evaluation system - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cognitive function evaluation system capable of evaluating a cognitive function relating to the working memory function of a subject and highly accurately detecting the decline and fault of the cognitive function by a simple method which is easy to understand for the subject. <P>SOLUTION: First task presentation processing of making the subject count a plurality of objects displayed at a display means is performed, and the subject is made to memorize a counted result. Thereafter, as second task presentation processing, task presentation processing of displaying a task image for making the subject count the plurality of displayed objects and making the subject add and memorize a re-counted result and the result counted and memorized in the first task presentation processing is performed. Thereafter, as third task presentation processing, the third task presentation processing of displaying a task image for making the subject count the plurality of displayed objects and making the subject add a re-counted result and the result added and memorized in the second task presentation processing is performed further. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

The present invention relates to a cognitive function evaluation system that evaluates a subject's cognitive function, and relates to a mechanism for evaluating a cognitive function by presenting an object according to a predetermined categorization means and receiving a response of the subject to the presented object. In particular, it is a technique useful for detecting a failure or functional deterioration of working memory of frontal lobe function in patients with dementia such as Alzheimer's disease.

In general, Alzheimer-type dementia is a disease that causes higher-order dysfunction, and is known to increase with age and account for the majority of dementia in the elderly. As a cause of Alzheimer type dementia, it is known that excessive accumulation of amyloid β protein is triggered by a decrease or disappearance of nerve cells.
However, the treatment of dementia has not been effective so far, and the actual condition is that the current symptoms are maintained or alleviated by occupational therapy.

  However, even if such treatment for dementia is carried out by occupational therapy or rehabilitation, treatment cannot be started without knowing if it is dementia in the first place. A simple and effective method for determining whether or not a person has dementia has been awaited.

Therefore, conventionally, as a test for evaluating the cognitive function of subjects, there is a reading span test (a test that presents a sentence including an underlined word, presents several sentences, and then answers the underlined word). Although it has been used, the reading span test has the disadvantage that it is highly suitable for testing language functions and is not suitable for evaluating only the functions of the original working memory.

In addition, as a technique for evaluating the cognitive function of a subject, a system for detecting a failure in a spatial working memory has been proposed (for example, Patent Document 1).
In Patent Document 1, although it was effective in detecting an obstacle in determining the coordinate system of the object and the self-body in the visual space, that is, an obstacle in the spatial working memory, the frontal lobe which is considered to have a great relationship with a decline in cognitive function There were inconveniences such as failure of functional working memory and degradation of function could not be evaluated.

JP 2005-137629 A

In dementia, it has been reported that working memory impairments in frontal lobe function appear relatively early in the onset of dementia, but there are still many unexplained mechanisms for the development of these disorders .
However, even if the mechanism of the onset itself remains unclear, early detection of dementia can be performed by taking advantage of the fact that impairment of working memory in frontal lobe function appears from a relatively early stage of onset of dementia. I can expect.

Here, working memory in frontal lobe function means temporal function of information in order to demonstrate functions such as planning, time judgment, logical thinking, attention (and its persistence), rule understanding, etc., which are frontal lobe functions. This temporary storage is called working memory.
This is because, in a computer system, when a CPU executes a process, a program or a process is being processed in a main memory (RAM: random access memory) as a temporary work area, in addition to a long-term memory called a fixed disk (hard disk). This information is temporarily stored and the process is executed, but it is similar to the process of the computer system when the CPU is compared to the frontal lobe and the RAM is compared to the working memory.

FIG. 14 is a multiple component model diagram by Badley for explaining the function of the working memory. As shown in FIG. 14, the working memory of the human frontal lobe function includes visual space memorization memo (stores visual and spatial information), episode buffer (related to reference and retrieval of information from long-term memory), phonological loop ( (Related to language processing) and a central execution system that controls the whole.
The working memory is closely related to the frontal lobe (particularly the prefrontal cortex), and the frontal lobe (particularly the prefrontal cortex) can be indirectly evaluated by evaluating the working memory.

And in relation to the fact that impairment of working memory in frontal lobe function appears from a relatively early stage of the onset of dementia, an early detection and evaluation system for dementia can be established by building a working memory evaluation system. It can be expected that effective rehabilitation will be possible by utilizing this.

Therefore, in the present invention, as a method for evaluating a working memory, “storing”, which is a drawback of a presentation problem in a test method based on “remembering and remembering”, which is a method that has been used well so far. Focusing on working memory and functions closely related to working memory (visual space memorization memos, phonological loops, and functions of the central execution system in processing related to working memory) The purpose is to build an evaluation system.

In addition, in order to overcome the shortcomings of “reading span test,” the specific gravity of testing language functions is high and it does not lead to the evaluation of the original working memory. Paying attention to the "mechanism that holds information necessary for execution for the period necessary for task execution", a means for presenting a count task for displaying objects and counting objects, and adding the results counted for each screen one after another The purpose is to evaluate the function to temporarily store the count result and the addition result only for the period required for the task execution by combining the means for presenting the task.

In the present invention, the task of counting and storing visual objects is presented while eliminating sentence grasping as much as possible, and on the next task screen, the counting task is further performed and then counted and stored in the previous task. The subject is repeatedly presented with a series of task processing, “execution and storage of the task, and reading of the stored information” while performing a series of tasks such as presenting the result and the task to be added and temporarily storing the addition result. Therefore, we will build a system that positively evaluates the function of “holding only for the period necessary to accomplish the task”.

  Specifically, it is a cognitive function evaluation system that evaluates a subject's cognitive function, and displays a display means for displaying objects such as characters and figures, and a plurality of objects are displayed on the screen of the display means. First task presentation processing means for presenting a task for causing the subject to count the number of objects and storing it as a first count result; and as a next task, a plurality of objects are displayed on the screen of the display means. A second task presentation processing means for causing the subject to count the number of displayed objects, adding the count result and the first count result, and storing a task for storing the addition result; An addition result reception processing means for obtaining an input of the addition result and receiving the addition result as input data, and the input by the addition result reception processing means. Based on the data, characterized in that and a correctness determination means for determining the correctness of the total number at which the addition result of the object displayed on the screen of the display means. Therefore, counting visual objects means that it is necessary to memorize for a short time which objects have been counted, and it can be expected that work will be performed using working memory. It becomes possible to evaluate the function of the working memory.

  In addition, by repeating the task presentation processing by the second task presentation processing means a plurality of times, the task display screen has three pages or (when the task presentation processing by the second task presentation processing means is one time, the task display screen The total number of pages of 2 is 2 pages, and the total number of pages on the task display screen is 3 pages by repeating twice), which can be further increased, and detection of mild cognitive impairment and functional deterioration is also possible It becomes.

  In addition, after executing each task presentation process by each task presentation processing means and before executing the next task presentation process, on the screen of the display means so as to disturb the subject's memory, By providing a disturbing screen display means for displaying the disturbing screen, or by changing the display time of the disturbing screen (providing a delay time) in the disturbing screen display means, the storage capacity of the subject's working memory can be used up.・ Discovery or recognition of cognitive dysfunction by erasing information temporarily stored in the subject's working memory due to disturbing stimuli, overwriting with disturbing information, or requiring longer memory retention time It becomes possible to evaluate the function more effectively.

In addition, the object to be counted can be reset in a short time by presenting the task of changing the number of objects to two or more and changing the number of objects for each screen and adding the number. This will lead to the evaluation of the subject's ability to erase and rewrite the working memory.

Further, according to the present invention, means for presenting a predetermined object is provided, the presented object is counted, the count result is temporarily stored in the subject's working memory, and then read from the working memory, and the previous count result is obtained. By providing a means for presenting a task to be added to and presenting a task to repeat this, the working memory function of the subject's frontal lobe function can be evaluated easily and accurately.

In addition, since the screen display and delay time adjustment to prevent the subject's access to the working memory are incorporated in the task, the working memory function of the subject's frontal lobe function can be evaluated more accurately.

Therefore, working memory impairment in frontal lobe function, especially in patients with dementia such as Alzheimer's disease, especially in relation to the fact that impairment of working memory in frontal lobe function appears from a relatively early stage of onset of dementia. It is useful for the detection of dementia, etc., and is effective in enabling early detection of dementia, enabling early treatment, and contributing to early recovery of patients.
Furthermore, since working memory in frontal lobe function can be stimulated in a short time, repeated evaluation tests every day are useful for rehabilitation of patients with dementia.

It is a functional block diagram in one embodiment of a cognitive function evaluation system of the present invention. It is a figure which shows the processing flow at the time of the test by the cognitive function evaluation system of this invention. It is a figure which shows the menu screen which selects a subject test. It is a figure which shows the flow of a screen display of the subject test 1. FIG. It is a figure which shows the flow of the screen display of the assignment test 2 and the assignment pattern 3. It is a figure which shows the flow of a screen display of the subject test 4. FIG. It is a figure which shows the figure which shows the flow of a screen display of the subject test. It is a figure which shows the figure which shows the flow of a screen display of the subject test. It is a figure which shows the figure which shows the flow of a screen display of the subject test. It is a figure which shows one Example of the data structure of a test pattern. It is a figure which shows one Example which shows the structure of the data for evaluation. It is a table | surface which shows the number-of-subjects distribution according to age. It is a table | surface which shows the test result according to a generation. It is a multiple component model figure explaining the function of a working memory.

  The best mode for carrying out the present invention will be described in detail with reference to the accompanying drawings.

FIG. 1 is a functional block diagram in an embodiment of a cognitive function evaluation system of the present invention.
First, the outline of the system configuration of the cognitive function evaluation system of the present invention (hereinafter referred to as “the present evaluation system”) will be described with reference to FIG.

<Outline of system configuration>
One embodiment of the evaluation system includes a control unit 10, a storage unit 20, a display unit 30 that displays a screen on a display device 32 such as a CRT or LCD display, a touch panel 42, a keyboard, a mouse 46, or a touch pen. An input receiving unit 40 that receives an input from an input device, and an external interface unit 50 are provided. Note that the display device 32 can be configured so as to include a touch panel 42 in its display unit (such as a liquid crystal display device with a touch panel).

The display unit 30 performs display memory access control, display data transfer to the display device 32, and timing control, and is generally composed of a display control LSI, a display memory, or the like. It may be realized by a chip set, a RAM 24 and a program.

The control unit 10 includes a task selection unit 11, a task generation unit 12, a task presentation unit 13, an interference processing unit 17, and the like, and generates menu screens and task test screen data by referring to necessary data from the storage unit 20. In addition to functioning as a problem presentation processing means that displays and presents on the display device 32 via the display unit 30, it functions as a correctness determination means for performing correctness determination processing of the input result data by the correctness determination section 14.

Further, the control unit 10 functions as an input receiving unit that receives an input instruction obtained by the subject operating the touch panel or the like via the input receiving unit 40. In addition, when the task test is executed, the required time measuring unit 15 In addition to performing processing for measuring the time required for execution, the evaluation data generation unit 16 functions as an evaluation data generation / output unit that generates and outputs evaluation data based on the input result at the end of the task test.

The storage unit 20 includes an operating system (OS) that is a management program for the entire system, a main program for configuring the evaluation system, and various programs 22 for configuring the control unit 10 and tests serving as a base for problems. In addition to storing pattern information 23 and image data 26 of various objects to be displayed, a RAM (Random Access Memory) 24 and a non-volatile memory 25 are provided as working memories of this system.

Here, the OS, various programs 22 and the test pattern information 23 which is the base of the problem are generally stored in the hard disk device 21, but the present invention is not limited to this, and may be stored in the nonvolatile memory 25. Good.

The external interface unit 50 mediates access to the external storage 56 such as a memory card or an external HDD, connects to a server device via a LAN via the communication device 54, or connects to a network such as the Internet or transfers data. And output to the printer 52. Note that the external interface unit 50 and the input receiving unit 40 may be hardware independent of the control unit 10 (or cooperation processing with software), or realized as a part of the control unit 10 by a chip set or a program. You may make it do.

Next, an outline of the processing of this evaluation system will be described focusing on the operation of the control unit 10 and its functional blocks.
<Outline of processing of this evaluation system>
The control unit 10 and each functional block (the task selection unit 11 to the disturbance processing unit 17 and the like) store a management program (OS or the like) of the entire system constituting the program 22, the main program of the evaluation system, and various control programs. This is realized by loading the data into a random access memory (RAM) 24 and executing each process by a CPU (Central Processing Unit) (not shown).

When the main program of the evaluation system is loaded and executed, the control unit 10 acquires information on the menu screen from the storage unit 20 and generates a menu screen (FIG. 3).
Then, the information is converted into information that can be displayed on the display device 32 and displayed on the display device 32 by the display unit 30 that performs display control at the timing of access to the display memory or requested by the display device 32.

The subject operates the touch panel 42 or the mouse 46 to select one or more of the task tests 61 from the menu screen, and then clicks the practice icon (button) 62 or the main test execution icon (button) 63. When any one is selected, the task selection unit 11 acquires information on the selection result of each icon or button via the input reception unit 40.

A display device with a touch panel is an input device having a pressure-sensitive transparent input portion that is finely divided into predetermined areas or cells on a display screen, and a subject presses the predetermined divided area (cell) with a finger or the like. Thus, a method of detecting the pressed portion is generally used, but the method is not limited to this, and any method may be used as long as the indicated position can be determined. For example, matrix system, resistive film system, surface acoustic wave system, optical system (infrared shielding system, etc.) or electromagnetic induction system, LCD system with built-in optical sensor, image recognition system using CCD, vibration detection system (DST), acoustic pulse The coordinates designated by the subject may be detected by a position detection mechanism such as a recognition method. Alternatively, a capacitance method combined with a touch pen may be used.

The assignment generation unit 12 generates an assignment test after acquiring the test pattern information (see FIG. 10) corresponding to the selected assignment from the test pattern information 23 of the storage unit, and the assignment presentation unit 13 Is constructed in a GUI format (graphical user interface format) as a task composed of text and figures that can be intuitively understood by the user, and displayed on the display device 32 via the display unit 30 (see FIGS. 4 to 9). .

The interference processing unit 17 intervenes in the task presentation processing of the task presentation unit 13, and generates and displays a disturbance screen between the task screen and the next task screen so as to interfere with the working memory function of the subject. Or generate and display a screen that displays nothing (blank screen), or adjust the delay time until the next task screen is displayed.

Whether the control unit 10 waits for an input operation of the touch panel or the like by the subject during the task test, and shifts to the next task test screen based on the input result, or finishes the current task test and makes a correct / incorrect determination. Judging.

When the running task test is completed, the control unit 10 generates and displays an answer acceptance screen, waits for an input operation such as a touch panel by the subject, and the correctness determination unit 14 determines whether the task test is based on the input result. Make a correct / incorrect decision.
The required time measuring unit 15 measures the time required for the task test screen processing (when a plurality of test screens are displayed, the total required time is also calculated).

When all of the selected tasks are completed, the evaluation data generation unit 16 generates test results as evaluation data in a predetermined data format based on the correctness determination and required time information (see FIG. 11). , Firstly stored in the storage unit 20 and output to an external storage 56 such as a USB memory.

In the above description, the subject is described on the assumption that one or more desired task tests are selected from the task tests 61 displayed on the menu screen. However, the present invention is limited to this. Instead, for example, when the “main test” icon (button) in FIG. 3 is selected, all of the registered task tests may be executed.

Next, the processing flow of this evaluation system will be described with reference to FIG.

<Test preparation>
The subject or its assistant (including a doctor, nurse, occupational therapist, etc., the subject's family, etc.) activates the power supply of the cognitive function evaluation system 1 and sets the main program of the cognitive function evaluation system. to start. The main program is loaded into the RAM, and the control unit 10 starts processing by the evaluation system 1 (step S1).

This evaluation system requires input of information such as age, gender, and subject ID, and performs mode setting or initial setting based on the input result by the subject or its assistant (step S2).

In the setting process or initial setting of the mode, in addition to prompting for the subject's age and subject ID, a test pattern that is the basis for a given task was registered in advance according to the usage status of the evaluation system so far. In the above, it is possible to select which pattern is to be incorporated (the basic pattern is 7 patterns as described later, but after preparing various patterns separately).

As for the assignment display screen used in this evaluation system, screen data can be registered in advance in the storage unit 20 for each assignment test, and the registered screen data can be read and displayed for each assignment test ( In other words, the display is fixed for each task test). Or, instead of a fixed screen display for each test, initial types of objects to be displayed, the number of upper limits, the number of pages on the assignment display screen, the transition time (delay time) for changing from the assignment display to the next assignment display screen, etc. It can be adjusted by setting, or it can be adjusted based on the value generated by random numbers each time.

This is compared with the data accumulated in the “basic experiment by healthy subjects” described later and the results of the test results of this evaluation test conducted on subjects suspected of having dementia. In a situation where comparative evaluation of cognitive functions is performed, it is desirable to unify the delay time and interference screen for each task test, and to display a fixed screen. (B) On the other hand, In such a situation, it is desirable to generate various test patterns to expand the range of subjects, so the purpose is to ensure flexibility suitable for such applications.

<Execution test (overall process flow)>
When the mode setting and initial setting are completed, a menu screen is displayed (step S3).
When the subject or the assistant gives an instruction to select a task test selection icon (button) 61 constituting the menu screen (FIG. 3) (step S4), the control unit 10 responds to the task test instructed to be selected. The test pattern information 23 is read from the storage unit 20 (in the case of a plurality of test patterns), and the task generation unit 12 performs a task based on the test pattern information 23 stored in the storage unit 20 and the image data 26 of the specified object. A test is generated, and the task is configured by the task presentation unit 13 in a GUI format (see FIGS. 4 to 9) that the subject can recognize on the display screen (step S5).
This completes the preparation by the subject or his / her assistant before starting the test.

Next, the control unit 10 waits for an input instruction from the subject (step S6), and when a “practice start” icon (button) or a “execute test” icon (button) is instructed (YES in step S6), An assignment explanation screen for the selected assignment test is displayed (step S7).

When the “start” icon (button) is selected and indicated on the assignment explanation display screen, the actual assignment screen (first sheet) is displayed (step S8).
The subject performs the task, and temporarily stores the result of the examination of the first task screen in the subject's own working memory.

After that, when the control unit 10 receives a “transition instruction to the next task screen” by the subject (YES in step S9), the control unit 10 adjusts the display switching timing in order to consume the time that can be stored in the working memory of the subject. , Or display the obstruction screen that has the effect of consuming the subject's working memory capacity, erasing information temporarily stored in the subject's working memory due to obstruction stimuli, or overwriting with obstruction information Above (step S10), the task screen of the next page is displayed (step S8).

Here, the display screen adjustment means that a blank screen (a screen that displays nothing) is displayed, and a certain time interval is left until a task on the next page is displayed.

  When the page number of the assignment screen set for each assignment test is completed (NO in step S9), an answer reception screen for the assignment is displayed, and an input of an answer result for each assignment test is accepted, and a required time measurement unit The total of “the time required from the task displayed on each page to the next task (specifically, the instruction to select the“ next ”icon (button))” measured by 15 The calculated value is temporarily stored in the RAM 24 (step S11).

  The correctness determination unit 14 determines the correctness of the received answer result, temporarily stores the correctness determination result in the RAM 24, and displays the correctness determination result on the screen (step S12).

Further, a screen display requesting whether or not to re-challenge the same task test is performed (step S13), and when a re-challenge icon (button) for the same task test is selected (YES in step S14), Returning to the explanation display screen of the subject, the same processing is repeated (after step S7).

  If the same task test re-challenge icon (button) is not selected, it is determined whether or not the next task test remains (step S14), and the next task test that has not yet been executed remains. In step S7, the process after step S7 is repeated after the explanation of the next problem is displayed.

  When all the set task tests have been completed (NO in step S14), the control unit 10 requests an input as to whether or not to end the entire test (step S15), and a task test end icon (button) is selected and instructed. Then, the evaluation data generation unit 16 aggregates the test results for each task test, and generates test result evaluation data (see FIG. 11) based on the response time and input result data required for the task processing. After that, it is displayed on the screen (step S16). Then, the test result evaluation data is output and recorded in the HDD 21 of the storage unit 20, the non-volatile memory 25, or an external storage 56 such as a memory card (step S17).

Alternatively, the control unit 10 evaluates the test result to a server or a terminal device of an inspection organization such as a hospital, a university, or a rehabilitation center via the external interface unit 50 or the communication device 54 and a network such as the Internet. The data for use may be transmitted. This allows the subject to be evaluated for cognitive function without going to a laboratory.

<Execution of assignment test (execution of individual assignment test)>
Next, execution of individual task tests will be described in detail with reference to FIGS.
Here, 7 test patterns are described as an example. However, the present invention is not limited to this, and the type of objects to be counted can be appropriately changed, and the number of objects to be displayed can be appropriately changed. Needless to say.

(1) Assignment test 1 (no delay time)
As an example, FIG. 4 shows the transition state of the screen display of assignment test 1.
Task Test 1 presents a task display screen on which an object (apple) is displayed. When the subjects have counted, touch the “Next” icon (button) to move to the next task display screen. The task is to add the number of objects (apples). In task test 1, no time difference (delay time) is provided for switching between screens.

Here, the object to be displayed may be anything such as a figure, a photograph, a character, or a symbol as long as it can be visually grasped. For example, in the case of a figure representing a tangible object, a character string such as an apple, banana, or orange. Even if it is expressed by, it is desirable that it is replaced with a short word as much as possible (3 to 4 sounds or less in the title) or is simple and anyone can know and intuitively understand. Of course, it may be a simple figure such as a pentagon, a rectangle, a triangle, or a circle, or it can be a mode in which a given figure is distinguished by color (display green ○ and red ○ several times, Count the number of red circles). Furthermore, a short character string (for example, “A”, “I”, “1”, “I”, “A”), etc., may be a character, a number, a symbol itself, or a character string is designed. It may be what you did. Even when characters are used, font data, that is, image data is still used when displayed on the screen, so that it can be adopted in this evaluation system in the same manner as graphics.
In this way, by eliminating as many sentences as possible and counting simple visual objects, the specific gravity of testing language functions, as seen in the reading span test, is high, and evaluation of the original working memory The effect of being able to overcome the disadvantage of “not connected” and mainly evaluate the function of the working memory is obtained.

Hereinafter, the processing will be described in detail with reference to FIGS. 1 and 2 as appropriate.
When the subject test 1 is selected by the test subject and the “practice start” icon (button) or “main test execution” icon (button) is selected and instructed, the test starts (YES in step S6). A problem explanation display screen 100 is displayed (step S7). In the problem explanation display screen 100, it can be seen that the type of the object to be displayed is “apple” and the “quantity” is “counted” and added one after another. .

  Then, when a “start” icon (button) 120 is selected and instructed by the subject on the task explanation display screen 100, the task actually starts, and the task presentation unit 13 of the control unit 10 has been generated or registered in advance. The data on the first assignment display screen is taken out from the storage unit 20 and displayed on the display unit 30 as the first assignment display screen 101 (step S8).

In the first task display screen 101, the subject content is that the number of displayed “apples” is counted and temporarily stored until the task on the next page is processed. Confirm the position of the “apple”, assign a number to each “apple”, count the number of “apples”, verbalize the number, and count the result (first count result). Temporarily store it in its working memory.
In this task presentation process, each of the subject's working memory functions, such as inducing a counting error due to a decrease in the function of “memorizing which object was counted”, etc., is presented by presenting the series of operations to the subject. You can test the element effectively.
When the counting of the assignment display screen on the first page is completed, the subject selects and instructs the “next” icon (button) 130.

Here, since there is the next page (YES in step S9), the process proceeds to step S10. However, in test pattern 1, there is no setting for disturbing screen display, and the display timing adjustment time (delay time) is set to 0. Therefore, the second screen 102 as the next task screen is immediately displayed (step S8).

On the second screen 102 of the assignment, it is assumed that the number of displayed “apples” is counted and added to the first count result that is the result of the assignment processing on the previous page. Is done.
In the test subject, the number of displayed “apples” is counted and the count result is temporarily stored in the working memory, while the number of apples counted on the first screen 101 of the task (first count result) is stored in the working memory. Addition processing is performed after extracting from. Then, the addition result is temporarily stored in the subject's own working memory.

Similarly, the third screen 103 of the task is displayed (step S8). On the third screen of the task screen, the number of displayed “apples” is counted, and the previous task processing result is counted. It can be seen that the result of the addition and the content of the task to be added further.
In the subject, the number of “apples” displayed on the assignment screen on page 3 is counted and the count result is temporarily stored in the working memory, while the number of apples counted so far (the first addition result) After reading from the working memory and adding to the count of the task screen on the third page, the obtained addition result (second addition result) is temporarily stored in the subject's own working memory.

  In the task test 1, the test is completed on the three task screens. When the “next” icon (button) 130 is selected and instructed by the subject, the task test ends (step S9) and the answer Is displayed (step S11).

The control unit 10 reads out the second addition result (the total number of apples on the three task screens), which is the result of all task processing, from the subject's working memory, and touches the touch panel to display the result. The data received by the input receiving unit 40 is temporarily stored in the RAM 24 as input result data. When the input is completed and a “complete” icon (button) is selected and instructed, the correctness determination unit 14 performs correctness determination based on the input result (step S12).

In the correctness determination, the number of objects and the total number of objects for each assignment page are registered for the number of objects to be counted (see FIG. 10), and the determination is made by comparing the total number with the input result data.
As for the correct numerical value of the task test 1, 23 pieces are obtained by referring to the data stored in the row = “TEST1” and the column = “the number of objects to be counted” in FIG. Since the input result data by the subject is also “23”, it is determined as the correct answer.
If the answer is correct, a display screen indicating “correct answer” is displayed. If the answer is incorrect, a display screen indicating “incorrect answer” is displayed (not shown).

Further, the control unit 10 displays the time (t1) from when the first screen 101 of the assignment is displayed until the “next” icon (button) is selected and instructed, and the second screen 102 of the assignment. The time (t2) from when the “next” icon (button) is selected and instructed until the “next” icon (button) is selected and instructed after the third screen 103 of the assignment is displayed Each information of the time (t3) and the total time (T = t1 + t2 + t3) are temporarily recorded in the RAM 24.

(2) Task test 2 (with delay time)
As shown in FIG. 5, in the task test 2, as a modified example of the task test 1, a process of adjusting the time until the next task screen is displayed (adding a delay time) after displaying each task screen. Is added (step S10). The purpose is to evaluate whether or not the memory of the subject's working memory is retained even if there is a delay time.

  As a method for adjusting the time, as shown in FIG. 5, “disturbing screen type A” 70A is inserted for a predetermined time. The delay time is set to 1 second in the effect experiment described later, but can be set to a different value. This time adjustment process is executed by the process of step S10 in FIG. In addition to the example shown in FIG. 5, the disturbing screen type A may be a screen that displays nothing (blank screen).

As described above, by adjusting this time, the temporary storage time in the subject's working memory is extended, and by affecting the test results, it effectively acts as a parameter contributing to the detection of dementia.

(3) Task test 3 (Evaluation of passive disturbance in delay time)
As shown in FIG. 5, the task test 3 is performed by inserting a “disturbance screen type B” 70 </ b> B as a modified example of the task test 2 for a predetermined time. The process of inserting the disturbing screen and adjusting the display time is executed by the process of step S10 in FIG.

The purpose of this test is to evaluate whether the memory of the subject's working memory is retained when information other than the object (object) to be counted is presented. Here, the object (chicken) that is not associated with a number is simply presented as information other than the object (object) to be counted, so the subject does not intend to learn the object type of the disturbing screen. In addition, the evaluation of “passive disturbance” is performed in the sense of receiving disturbing stimuli.

Specifically, in Task Test 2, a screen that displays nothing is inserted for the purpose of extending the subject's working memory storage time, but in Task Test 3, the screen on which a predetermined object is displayed, In order to be inserted as a disturbing screen, it acts to waste the capacity of the subject's working memory, and the potential charged in the nerve cells constituting the subject's working memory is discharged by the disturbing stimulus from the disturbing screen, It works to erase the necessary information (counting result or addition result) temporarily stored, or it causes unnecessary charge to other nerve cells due to unintentionally acquired information by disturbing stimulation. It works to discharge the potential of nerve cells in the working memory that temporarily stores necessary information, In other words, because the information obtained by the disturbing stimulus is overwritten with the necessary information, the size of the subject's working memory tends to be reduced due to dementia, or the function of the working memory It has the effect of helping to detect that it has been lowered.

(4) Task test 4 (Evaluation of active disturbance in delay time)
As shown in FIG. 6, in the task test 4, as a modification of the task test 3, as in the task explanation screen 400, not only the number of objects (apples) is counted, but also different types of objects (animals) By presenting a problem to be memorized for (type), a “disturbance screen type C” 70C including a display of a predetermined animal or a “disturbance screen type D” 70D including no display of an animal is inserted for a predetermined time. Do.

In this test, an object that is different from the object (chicken) inserted as an obstruction screen in task test 3 and does not associate with a number (giraffe in the figure) is displayed between each task display screen for a predetermined time (for example, (1 second) Inserted and displayed as an obstruction screen, telling you to hear what the object on this screen was (Kirin) at the end, and trying to memorize information other than the object (object) to be counted The purpose is to evaluate whether or not the memory of the subject's working memory is retained when a purpose-oriented disturb is inserted. In this regard, in the sense that the subject intends to learn the object type of the disturbing screen, it will be called “active disturb” evaluation.

Specifically, such a short-time display of disturbing screens forces the subject to store another object in the working memory (displaying the disturbing screen for a short time during the work). However, storing the contents of the display means that information is stored in the working memory because it is in the middle of work and is displayed for a short period of time). In addition to wasting capacity, the potential charged in the nerve cells that make up the working memory of the subject was discharged by the disturbing stimulus from the disturbing screen and temporarily stored. ) Or other information to temporarily store the information acquired by the disturbing stimulus. Information that has been obtained by intentionally obtaining a charge from a cell, in which case it acts to discharge the potential of a neuron in the working memory that temporarily stores the information of the count result or addition result, or by disturbing stimulation By overwriting the necessary information, it helps to detect that the subject's working memory tends to decrease in size due to dementia, or that the working memory function is degraded There is an operational effect.

The object used as the display content to be stored in the disturbing screen display may be any figure, photograph, character, symbol, etc. as long as it can be grasped visually. For example, in the case of a figure representing a tangible object, It should be as simple as chickens, elephants, giraffes, and cars (3 to 4 sounds in the name) and intuitive to understand. Of course, it may be a simple figure such as a pentagon, a quadrangle, a triangle, or a circle, or a mode in which a predetermined figure is stored in color (how many color squares are displayed, etc.). Furthermore, a short character string (for example, “A”, “I”, “1”, “I”, “A”), etc., may be a character, a number, a symbol itself, or a character string is designed. It may be what you did. This is mainly to increase the effect of evaluating the function of the working memory while eliminating the grasp of sentences as much as possible and suppressing the specific gravity to test the language function as much as possible.

(5) Task test 5 (Evaluation of active disturbance without delay time)
As shown in FIG. 7, in the task test 5, as a modified example of the task test 1, the object test 1 has one type of object (only apples), while the object type has two types (see FIG. 7). In this example, apples and bananas are used, and then the number of objects on one side is counted. Note that no disturbing screen display is provided in step S10, and display timing adjustment (delay time) is set to zero.

In this test, information on only apples is selected from a task display screen that contains both apples and bananas, and when a disturbance stimulus called bananas is entered, the number of apples is accurately stored in the subject's working memory. The purpose is to evaluate whether it is possible.
It should be noted that the number of types of objects is not limited to two, but can be more than that, and the number of both types can be counted as two types of objects.

(6) Task test 6 (Evaluation of erasing and rewriting of working memory)
As shown in FIG. 8, in the task test 6, as a modified example of the task test 5, two types of objects (apple and banana in the example of FIG. 7) are used, and the types of objects to be counted for each screen are changed. It is a challenge to change and count.

In this test, the types of objects (objects) to be counted are changed for each screen, and the numbers are added. However, it is possible to evaluate whether the objects to be counted can be reset in a short time. This leads to evaluation of the erase / rewrite function.

Specifically, since the tasks are counted in the order of apple → banana → apple for each screen, 6 apples and 3 bananas are displayed on the task display screen 601. First, it is required to count the number of apples (6). In the next task display screen 602, four apples and five bananas are displayed. The number of bananas (5) is counted, and the number of apples (6) on the first screen 601 of the task is determined by the subject. It is required to read from the working memory and add. As a result, 6 + 5 = 11 are calculated and required to be temporarily stored in the working memory of the subject.

Then, when the task display screen 603 is displayed, 5 apples and 3 bananas are respectively displayed. The number of apples (5) is counted, and 11 pieces of information obtained as a result of addition are counted. It is required to read from the working memory and add. As a result, 5 + 11 = 16 calculation results are obtained, and input on the answer reception screen is required.

Here, instead of counting and adding in order of apple → banana → apple for each screen, the task may be a content of counting and adding in order of banana → apple → banana.
Note that no disturbing screen display is provided in step S10, and display timing adjustment (delay time) is set to zero.

(7) Task test 7 (Evaluation of working memory and suppression function)
In the task test 7, the task is “contents that count the number of bananas when apples appear on the task display screen, and count the number of apples when bananas appear”.

In this test, the suppression function, which is one of the frontal lobe functions, works in that the subject is required to perform a suppression process that does not count the specified specific type of objects among at least two types of displayed objects. The purpose is to evaluate whether the target number of objects can be accurately stored in the working memory of the subject.

  Specifically, since apples are displayed on the assignment display screen 701, it is required to count the number of bananas (six on the screen).

  After the answer acceptance process is performed, the second assignment display screen 702 is displayed, and after the same process, the third assignment display screen 703 is displayed, and the process proceeds to the answer acceptance process. .

Here, it can be set as a task of adding three pages consecutively as in the task tests 1 to 6, or the task can be simplified by obtaining an answer for each screen as in the example of FIG. it can.

In the case of the example in FIG. 9, the display of the assignment screen and the answer acceptance process are alternately repeated, so that the processes in steps S11 and S12 in FIG. 2 are performed immediately after step S8. However, the disturbing screen display in step S10 is not provided, and the display timing adjustment (delay time) is set to zero.

The number of pages on the above problem display screen is set to three by default, but is not limited to this, and may be two, four, or more.

<Variations of assignment display screen and obstruction screen display>
As for the task display screen generation process, fixed screen display data can be registered for each test pattern composing each task test. However, the object type can be changed for each task test, The number of displays can be changed each time.

(1) Selection of object type For example, for an object to be counted, some object types (apple, banana, cherry, mandarin orange, flower, etc.) are registered in the storage unit 20 together with the object ID (apple ID = 01). , Banana ID = 02, ...), mode setting or initial setting may be used to select which object is used, or an object ID is selected based on an integer generated by a random number, It is also possible to select and display an object corresponding to the ID.
Alternatively, when a flower is selected as an object, a plurality of flower colors may be prepared and the number of predetermined flower colors may be counted.

(2) Generation of assignment display screen For each test pattern, the type of assignment display screen (distinguishing whether to display one type of object or two types), presence / absence and type of interference screen, delay time, etc. In the case where 10 tables are set and stored in the storage unit 20,
Since the type of the problem screen 1 on the first page of TEST1 is understood to be type G1 (G1 = 1 type of object) with reference to the table of FIG. 10, the control unit 10 has one type of object ID (for example, apple ), The apple image data is acquired from the storage unit 20, and the eight random numbers generated are expanded to predetermined coordinate positions to generate the first page of the task screen.

Similarly, for type G2 (G2 = 2 types of objects), a predetermined number of two types of objects are generated and expanded on the screen display memory to generate a task screen.
As for the size and display position of each object, the screen display size of the display device is recorded (about 14.3 cm × 19 cm if the LCD display size is 10.4 inches). After recording the size as apple (1.6 cm x 1.6 cm), banana (length 2.1 cm, thickness 0.5 cm), etc., and adjusting the objects so that they do not overlap, An assignment display screen can be generated and displayed.

(3) Adjustment of obstruction screen and delay time As the obstruction screen, some object types (giraffe, chicken, elephant, fox, monkey, etc.) are registered in the storage unit 20 together with the object ID (Kirin ID = 11, chicken ID = 12,...), Based on an integer generated by a random number, an object ID is selected, and an object corresponding to the object ID is selected and displayed.
Similarly, for adjusting the delay time, in addition to a predetermined specified value (1 second, 2 seconds, etc.), an integer generated by a random number is limited to a predetermined upper limit value (for example, 5 seconds) and used. good.

In addition to collecting the basic data of the subjects, the following comparative tests (basic experiments) were conducted to confirm the effects of the invention.

<Outline of basic experiment>
The purpose is to detect the failure and deterioration of working memory in patients with suspected dementia, but as basic data for that purpose, it is useful to investigate the error rate of healthy subjects by age and to create a database. is there.

Therefore, healthy subjects were interviewed with MMSE, and those with MMSE scores of 24 points or more, a history of cerebrovascular disorder or head injury, and no neurological disease were taken as the criteria for inclusion.

Here, MMSE is one of the methods for diagnosing dementia and is called a mini-mental test. A doctor or other person conducting a test asks a patient a predetermined question and answers that question. Diagnosis and evaluation are performed by assigning scores to patient responses.
FIG. 12 shows the distribution of healthy subjects by age in basic experiments.

<Verification of results>
FIG. 13 shows the result of the evaluation test of the cognitive function for the subject using the evaluation system (error rate by age).
Hereinafter, the results for each test will be verified based on FIG.

(1) Influence of delay time (Problem Test 1, Problem Test 2)
In task test 1, the delay time was 0, and in task test 2, the delay time was 1 second. However, no significant difference occurred in about 1 second, and it was found that the subject's working memory was less affected. For this reason, cognitive dysfunction that has progressed to some extent is preferably about 1 second, but setting it to 2 seconds or longer may enable detection of milder cognitive impairment or functional deterioration. I can expect.

(2) Influence of disturbance when switching screens (Problem Test 3, Problem Test 4)
In the task test 4, the frequency of mistakes increases in the 40s, and a large amount of noise is mixed in the 40s, but it can be seen that the error rate in the 70s is basically high.

  In assignment test 3, the chicken's obstruction screen is displayed for 1 second, but since it does not present a new assignment, there is some familiarity with the test, and even in the older age, assignment test 1 and test 2 Compared with, the error rate is lower.

In Task Test 4, since “Another Animal (Giraffe)” is displayed as a new task (disturbing stimulus) between the counting tasks and it is required to remember it, the working memory capacity of the subject is reduced. It has the effect of causing extra consumption, erasing information temporarily stored in the subject's working memory due to obstruction stimuli, or overwriting with obstruction information, thus inducing forgetting the number already counted. , It can be seen that the error rate, which was improved by getting used to the test, is getting worse again.

(3) Influence of disturbance in the screen (Problem Test 5, Problem Test 6)
In the task test 5, although the wrong answers are seen in the 60s and 70s, the error rate is generally low. This is presumed to be because the disturbance in the same screen only needs to memorize the original problem, so that new working memory is not consumed.
The same applies to the task test 6.

(4) Effect of suppression function (Problem Test 7)
The error rate was zero in all ages. This is because the task is presented and the answer is received on the same screen, so there is little access to the working memory in the subject, so the influence of the suppression function is difficult to appear.

On the other hand, only this task test 7 has an error rate of 0 in all ages and 0 in high ages. This test is a test that does not require much working memory. It turns out that it is useful as a test for confirming lastly that functions other than the function, for example, the count function itself is normal.

<Summary>
(B) With the number of samples in the basic experiment (10 people for each age group), the error rate of the entire age group depends on the error rate of one person. Therefore, although there is some variation for each test pattern, the error rate increases with age, and it is shown that the error rate is significantly high in the 70s.

(B) In addition, the average error rate is shown in the lower part of Fig. 13, excluding the task test 3 whose error rate decreased due to familiarity as noise and excluding the task test 7 which is considered to have little effect on the working memory. However, according to this, it is possible to find a remarkably high error rate in the 70s. That is, it can be understood that the accuracy of detection of failure or functional deterioration of the working memory can be improved by selecting or statistically processing the evaluation result data of this evaluation test according to the nature of the test.

(C) In addition, according to the details of the answer results, it was found that most of the wrong answers were one difference from the correct answer, so that there was a mistake in counting the numbers. According to this, “counting error”, which is an error factor other than an error in reading and storing in the working memory, is limited by, for example, limiting the number of objects per screen to about 6 to 7 or less. It can be seen that if the occurrence is reduced, the detection rate of the failure or the like of the storage read function of the working memory can be improved more remarkably.
In addition, the cause of miscounting is that a work error occurs in the processing of the working memory in the work of assigning numbers to objects ("Relationship between this evaluation test and multiple components (2)" described later). Specifically, the object that has been counted once may be counted again due to a decrease in the function of “remembering which object is counted” or the function of “visual space memorization memo in working memory”. It is thought that work mistakes caused by skipping and counting were induced, work of linguistic working memory (counting objects as “1”, “ni”, “san”) and visual It is possible that there is a mismatch between working memory (object recognition).
From this, it can be seen that a decrease in the working memory function can be remarkably detected by increasing the number of objects (for example, 7 or more).

(D) In addition, even in the numerical repetitive test separately conducted in this sample, the results show a tendency to decrease as the age goes up, and there is a significant relationship between the age and the results of the numerical repetitive test. Correlation has also been confirmed between the results of the numerical recitation test and the counting test.

(E) It is known that the working memory function of the frontal lobe function declines in the elderly even in healthy people. According to the evaluation test in this evaluation system, the error rate of each evaluation test in the elderly Therefore, even in patients with dementia, it is possible to detect impairment or deterioration of the function of the working memory of the frontal lobe function even in patients with dementia.

(F) Such working memory functions are thought to decrease with aging, and by confirming the age dependence in the test method of this evaluation system, the function of dementia in the test method of this evaluation system is indirectly monitored. The effectiveness of detection and evaluation can be confirmed.

(G) According to this evaluation test, mainly in terms of the counting task of counting the number of display objects, the “specificity of testing language functions is high, such as the reading span test. It is possible to overcome the "defect that is not suitable for evaluation", and the language function is added in that the problem of memorizing the object type is added to the disturbing screen display such as the problem test 4 In consideration of not relating to the above, there is an effect that only the function of the original working memory is evaluated.

Finally, considering the effect of this evaluation test in relation to the multiple components in FIG.
(1) Checking the position of the object,
(2) Work to assign numbers to objects,
(3) Counting the number of objects,
(4) Work to verbalize the counted numbers,
(5) Temporary storage of verbalized numbers,
(6) Counting objects again in the next task (similar to (1) to (5)),
(7) Reading the temporarily stored numbers,
(8) Work to be added to the count result (9) Work including a work to store the addition result.

Among these, the work of (1) relates to the function of the visual space memorization memo in the working memory, and the work of (4), specifically, “1 = 1”, “2 = ni”, and so on. The work of verbalizing numbers is related to the function of the phoneme loop, (2) (3) (8), etc. are related to the functions of the central executive system, (5) (7) (9), etc. Related to function.
For this reason, it can be seen that it is possible to comprehensively evaluate the entire multiple components related to the working memory function.

As mentioned above, although embodiment of this invention was described in detail, this invention is not limited to said Example, It can implement | achieve as various other alternative examples.

Used to detect various types of disabilities, such as the discovery and differentiation of alcoholism, schizophrenia, mood disorders, etc., as well as training for people with mental disabilities, cerebral constitutional disorders, developmental disorders, etc. after rehabilitation It can also be used for welfare and rehabilitation purposes.

DESCRIPTION OF SYMBOLS 1 Cognitive function evaluation system 10 Control part 11 Problem selection part 12 Problem generation part 13 Problem presentation part 14 Correct / incorrect determination part 15 Time required measurement part 16 Evaluation data generation part 20 Storage part 21 Hard disk (HDD)
22 Program 23 Test pattern 24 RAM (Random Access Memory)
25 Nonvolatile memory 26 Image data

30 Display unit 32 Display device (LCD display, CRT, etc.)
40 Input acceptance unit 42 Touch panel 46 Input device (K / B mouse, etc.)
50 External interface unit 52 Printer 54 Network, communication device 56 External storage (memory card, external HDD, magneto-optical disk (CD, DVD, etc.))

60 Menu screen 61 Assignment test selection icon 62 Practice start icon 63 This test execution icon

70A Blocking screen type A
70B Interference screen type B
70C Interference screen type C
70D Interference screen type D

100 Assignment explanation display screen in assignment test 1 101 Assignment display screen in assignment test 1 (first sheet)
102 Assignment display screen for assignment test 1 (second sheet)
103 Assignment display screen for assignment test 1 (third sheet)
104 Answer reception screen 120 Task start icon 130 Icon for instructing transition to the next screen 140 Icon for notifying the system that input of the answer has been completed

400 assignment explanation display screen in assignment test 4 500 assignment explanation display screen in assignment test 5 501 assignment display screen in assignment test 5 (first sheet)
502 Task display screen for task test 5 (second page)
503 Assignment display screen for assignment test 5 (third sheet)

600 Assignment explanation display screen in assignment test 6 601 Assignment display screen in assignment test 6 (first sheet)
602 Assignment display screen for assignment test 6 (second sheet)
603 Assignment display screen for assignment test 6 (third sheet)

700 Task explanation display screen in task test 7 701 Task display screen in task test 7 (first sheet)
702 Assignment display screen for assignment test 7 (second sheet)
703 Assignment display screen for assignment test 7 (third sheet)

Claims (13)

A cognitive function for evaluating the cognitive function of a subject, comprising: object registration means for registering object information such as characters and graphics as image data; and display means for obtaining and displaying the image data of the object from the object registration means An evaluation system,
A plurality of objects are displayed on the screen of the display means based on the image data of the objects acquired from the object registration means, and the number of displayed objects is counted by the subject and stored as a first count result. First problem presentation processing means for presenting a problem;
As a next problem, on the screen of the display means, a plurality of objects are displayed based on the image data of the object acquired from the object registration means, and the subject counts the number of displayed objects, and the counting result And a second task presentation processing means for presenting a task for adding the first count result and storing the addition result;
An addition result reception processing means for requesting the subject to input an addition result and receiving the addition result as input data;
Based on the input data by the addition result reception processing means, correctness determination means for determining the correctness of the addition result that is the total number of the objects displayed on the screen of the display means;
Cognitive function evaluation system characterized by having
A cognitive function for evaluating the cognitive function of a subject, comprising: object registration means for registering object information such as characters and graphics as image data; and display means for obtaining and displaying the image data of the object from the object registration means An evaluation system,
A plurality of objects are displayed on the screen of the display means based on the image data of the objects acquired from the object registration means, and the number of displayed objects is counted by the subject and stored as a first count result. First problem presentation processing means for presenting a problem;
As a next problem, on the screen of the display means, a plurality of objects are displayed based on the image data of the objects acquired from the registration means, and the number of displayed objects is counted by the subject. , Second task presentation processing means for presenting a task for adding the first count result and storing it as the first addition result;
Further, as a next problem, a plurality of objects are displayed on the screen of the display means based on the image data of the objects acquired from the object registration means, and the number of displayed objects is counted by the subject. Third task presentation processing means for presenting a task for adding the count result and the first addition result to be stored as a second addition result;
An addition result receiving processing means for requesting the subject to input a second addition result and receiving the addition result as input data;
Based on the input data by the addition result reception processing means, correctness determination means for determining the correctness of the addition result that is the total number of the objects displayed on the screen of the display means;
Cognitive function evaluation system characterized by having
A cognitive function for evaluating the cognitive function of a subject, comprising: object registration means for registering object information such as characters and graphics as image data; and display means for obtaining and displaying the image data of the object from the object registration means An evaluation system,
A plurality of objects are displayed on the screen of the display means based on the image data of the objects acquired from the object registration means, and the number of displayed objects is counted by the subject and stored as a first count result. First problem presentation processing means for presenting a problem;
As a next problem, on the screen of the display means, a plurality of objects are displayed based on the image data of the object acquired from the object registration means, and the subject counts the number of displayed objects. And a second problem presentation processing means for presenting a problem to be added and stored as an addition result.
Further, as a next problem, a plurality of objects are displayed on the screen of the display means based on the image data of the objects acquired from the object registration means, and the number of displayed objects is counted by the subject. A third problem presentation processing means for presenting a problem for storing the addition result obtained by adding the count result and the addition result as a new addition result;
The task presentation processing by the first task presentation processing means and the task presentation processing by the second task presentation processing means are executed, and then the task presentation processing by the third task presentation processing means is repeated a plurality of times. Above,
An addition result receiving processing means for obtaining a final addition result from the subject and receiving the addition result as input data;
Based on the input data by the addition result reception processing means, correctness determination means for determining the correctness of the addition result that is the total number of the objects displayed on the screen of the display means;
Cognitive function evaluation system characterized by having
In addition, a screen for disturbing screen registration for registering information on the screen for disturbing the subject's task performance as image data is provided.
After performing each task presentation processing by each task presentation processing means, before the next task presentation processing is performed, the interference is displayed on the screen of the display means so as to disturb the subject's memory. The cognitive function evaluation system according to any one of claims 1 to 3, further comprising obstruction screen display means for displaying an obstruction screen based on the image data of the obstruction screen acquired from the screen registration means.
5. The cognitive function evaluation system according to claim 4, wherein the disturbing screen display means changes a display time of the disturbing screen.
In the disturbing screen registration means, two or more kinds of image data for constituting the disturbing screen are registered, and the disturbing screen is changed each time the disturbing screen is displayed by the disturbing screen display means. The cognitive function evaluation system according to any one of claims 4 and 5.
As the obstruction screen by the obstruction screen display means, an object type different from the display object to be counted in the assignment presentation process in the assignment presentation processing means is displayed, and further, the type of the object displayed as the obstruction screen is stored. The cognitive function evaluation system according to any one of claims 4 to 6, further comprising disturbing screen object storage task presentation means for presenting a task.
In the object registration means, register image data of two or more types of objects,
In the assignment presentation processing by the assignment presentation processing means, a plurality of types of display objects to be counted are specified, a specific type of object is specified, and only a display number of the specified type of object is counted. The cognitive function evaluation system according to any one of claims 1 to 3, further comprising a designated object count task presenting means for presenting.
In the object registration means, register image data of two or more types of objects,
In the task presentation processing in the task presentation processing means, the number of display objects to be counted is set to two types, and the order of specific types of objects to be counted in each task presentation processing is specified and specified. 4. A designated object order counting task presenting means for presenting a task for counting only the number of displayed objects of the type specified for each task presenting process in the order in which the task is presented. Cognitive function evaluation system according to one.
In the object registration means, register image data of two or more types of objects,
In the task presentation processing in the task presentation processing means, the number of display objects to be counted is set to two types, one type of object is specified, and the number of objects of the other type not specified is displayed. The cognitive function evaluation system according to any one of claims 1 to 3, further comprising non-designated object count task presentation means for presenting a task for counting objects.
A cognitive function for evaluating the cognitive function of a subject, comprising: object registration means for registering object information such as characters and graphics as image data; and display means for obtaining and displaying the image data of the object from the object registration means An evaluation system,
A problem is presented in which a plurality of objects are displayed on the screen of the display means based on the image data of the objects acquired from the object registration means, and the number of displayed objects is counted by the subject and stored as a count result. Task presentation processing means to perform,
In the task presentation processing in the task presentation processing means, the number of display objects to be counted is set to two types, one type of object is specified, and the number of objects of the other type not specified is displayed. A non-designated object counting task presentation means for presenting a task for counting
Count result reception processing means for requesting the subject to input a count result and receiving the count result as input data;
Correct / incorrect judgment means for judging whether the count result is the total number of the objects displayed on the screen of the display means based on the input data by the count result reception processing means;
Cognitive function evaluation system characterized by having
The data obtained by accepting the input operation by the addition result acceptance processing means, including the judgment process result by the correctness judgment means, or the processed data thereof is generated as cognitive function evaluation data, and is displayed or printed on the screen. Or an evaluation data generation / output means for storing and saving in an external storage device. 12. The cognitive function evaluation system according to claim 1, further comprising:
The cognitive function evaluation system according to any one of claims 1 to 12, wherein in each task presentation process by each task presentation processing means, an object to be displayed is four or less sounds in a name.

Images