JP2011051937A5 - - Google Patents

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JP2011051937A5
JP2011051937A5 JP2009202852A JP2009202852A JP2011051937A5 JP 2011051937 A5 JP2011051937 A5 JP 2011051937A5 JP 2009202852 A JP2009202852 A JP 2009202852A JP 2009202852 A JP2009202852 A JP 2009202852A JP 2011051937 A5 JP2011051937 A5 JP 2011051937A5
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Japan
Prior art keywords
lymphocyte
therapeutic agent
treatment
culturing
cancer
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Pending
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JP2009202852A
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Japanese (ja)
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JP2011051937A (en
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Priority to JP2009202852A priority Critical patent/JP2011051937A/en
Priority claimed from JP2009202852A external-priority patent/JP2011051937A/en
Publication of JP2011051937A publication Critical patent/JP2011051937A/en
Publication of JP2011051937A5 publication Critical patent/JP2011051937A5/ja
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Claims (15)

がん病巣部及び/又はがん病巣部を含む部位への加温処置を実施している被験個体に、前記の加温処置中及び/又は加温処置後に投与されるためのがん治療剤の製造における、リンパ球の使用。A cancer therapeutic agent to be administered during and / or after the above-mentioned heating treatment to a test individual carrying out the heating treatment to a cancer lesion part and / or a site containing the cancer lesion part Of lymphocytes in the manufacture of 加温処置を実施している被験個体に、前記の処置開始後1時間〜10日間後に投与されるためのがん治療剤の製造における請求項1記載の使用。The use according to claim 1 in the manufacture of a therapeutic agent for cancer to be administered to an individual subject undergoing warming treatment 1 hour to 10 days after the start of the treatment. 加温処置が38〜44℃である請求項1記載の使用。Use according to claim 1, wherein the warming treatment is 38-44 ° C. リンパ球が被験個体から採取されたリンパ球又はリンパ球前駆細胞を含有する細胞集団の培養により得られたリンパ球培養物である請求項1記載の使用The use according to claim 1, wherein the lymphocyte is a lymphocyte culture obtained by culturing a cell population containing lymphocytes or lymphocyte progenitor cells collected from a subject individual. リンパ球が抗CD3抗体の存在下での培養により得られたリンパ球培養物である請求項4記載の使用The use according to claim 4, wherein the lymphocyte is a lymphocyte culture obtained by culturing in the presence of an anti-CD3 antibody. リンパ球がフィブロネクチン、フィブロネクチンのフラグメント、もしくはそれらの混合物の存在下での培養により得られたリンパ球培養物である請求項5記載の使用The use according to claim 5, wherein the lymphocyte is a lymphocyte culture obtained by culturing in the presence of fibronectin, a fragment of fibronectin or a mixture thereof. リンパ球がリンパ球培養物から分離されたナイーブT様細胞集団である請求項1〜6いずれか1項に記載の使用 Use according to any one of claims 1 to 6, wherein the lymphocyte is a naive T-like cell population isolated from a lymphocyte culture. がん病巣部及び/又はがん病巣部を含む部位への加温処置を実施している被験個体に、前記の加温処置中及び/又は加温処置後に投与されるための、リンパ球を有効成分とするがん治療剤。   Lymphocytes to be administered during and / or after the above-mentioned warming treatment to a test subject who is performing warming treatment on the cancer lesion and / or the site containing the cancerous lesion A cancer therapeutic agent as an active ingredient. 加温処置を実施している被験個体に、前記の処置開始後1時間〜10日間後に投与されるための、請求項8記載の治療剤。   The therapeutic agent of Claim 8 for administering to the test individual | organism | solid which is implementing the warming treatment 1 hour-10 days after the said treatment start. 加温処置が38〜44℃である請求項8記載の治療剤。The therapeutic agent according to claim 8, wherein the heating treatment is 38 to 44 ° C. リンパ球が被験個体から採取されたリンパ球又はリンパ球前駆細胞を含有する細胞集団の培養により得られたリンパ球培養物である請求項8記載の治療剤。   The therapeutic agent according to claim 8, wherein the lymphocyte is a lymphocyte culture obtained by culturing a cell population containing lymphocytes or lymphocyte progenitor cells collected from a test individual. リンパ球が抗CD3抗体の存在下での培養により得られたリンパ球培養物である請求項11記載の治療剤。 The therapeutic agent according to claim 11 , wherein the lymphocyte is a lymphocyte culture obtained by culturing in the presence of an anti-CD3 antibody. リンパ球がフィブロネクチン、フィブロネクチンのフラグメント、もしくはそれらの混合物の存在下での培養により得られたリンパ球培養物である、請求項12記載の治療剤。 The therapeutic agent according to claim 12 , wherein the lymphocyte is a lymphocyte culture obtained by culturing in the presence of fibronectin, a fragment of fibronectin, or a mixture thereof. リンパ球がリンパ球培養物から分離されたナイーブT様細胞集団である請求項8〜13いずれか1項に記載の治療剤。 The therapeutic agent according to any one of claims 8 to 13, wherein the lymphocyte is a naive T-like cell population separated from a lymphocyte culture. リンパ球又はリンパ球前駆細胞を含有する細胞集団の培養により得られたリンパ球培養物と、がん病巣部及び/又はがん病巣部を含む部位を加温処置可能な装置を包含するがん治療システム。   Cancer including a lymphocyte culture obtained by culturing a cell population containing lymphocytes or lymphocyte progenitor cells, and a device capable of heating a cancer lesion and / or a site containing the cancer lesion Treatment system.
JP2009202852A 2009-09-02 2009-09-02 Cancer therapeutic agent Pending JP2011051937A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009202852A JP2011051937A (en) 2009-09-02 2009-09-02 Cancer therapeutic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009202852A JP2011051937A (en) 2009-09-02 2009-09-02 Cancer therapeutic agent

Publications (2)

Publication Number Publication Date
JP2011051937A JP2011051937A (en) 2011-03-17
JP2011051937A5 true JP2011051937A5 (en) 2012-11-01

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JP2009202852A Pending JP2011051937A (en) 2009-09-02 2009-09-02 Cancer therapeutic agent

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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2028266A4 (en) * 2006-06-09 2010-08-11 Takara Bio Inc Method of producing lymphocytes
JPWO2008143014A1 (en) * 2007-05-11 2010-08-05 タカラバイオ株式会社 Cancer treatment

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