JP2011036521A - Endoscope for biopsy diagnosis - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an endoscope for biopsy diagnosis capable of perfectly preventing the contamination or the like of a tissue sample and capable of extremely rapidly performing the treatment from the sampling of the tissue sample to staining and pathologic diagnosis. <P>SOLUTION: The endoscope for biopsy diagnosis is constituted so as to stain the tissue sample 100 sampled in the tissue sample sampling part 51 provided to the leading end of a biopsy specimen sampler 50 by arranging a staining solution absorbing and holding member 11 in a treatment instrument protruding port 5 to bring the tissue sample sampling part 51 into contact with the staining solution absorbing and holding member 11. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to an endoscope for biopsy diagnosis.

  Most endoscopes have a treatment instrument insertion channel inserted in the insertion section, and the tip of a biopsy specimen collection tool such as a biopsy forceps protrudes from a treatment instrument projection port arranged at the distal end of the insertion section. Thus, a tissue specimen can be collected from a living tissue.

  When a tissue sample is collected by the biopsy specimen collection tool passed through the treatment instrument insertion channel of such an endoscope, the biopsy sample collection tool is pulled out from the treatment instrument insertion channel. Then, the tissue specimen taken out from the biopsy specimen collecting tool is subjected to fixing, staining, preparation of an observation specimen, and the like, and a pathological diagnosis is performed by microscopic observation.

  However, if the tissue sample is transferred to various containers during the processing from the tissue sample collection to the pathological diagnosis, contamination of the tissue sample or conversely contamination from the tissue sample to the external environment occurs. There is a risk.

  Therefore, conventionally, an attempt has been made to prevent contamination and the like by providing a specimen storage container for storing a tissue specimen in the operation portion of the endoscope (for example, Patent Document 1).

WO2006 / 038634

  As in the invention described in Patent Document 1, if a specimen storage container is provided in the operation part of the endoscope and is used throughout the processing steps up to the pathological diagnosis, contamination to the tissue specimen is prevented to some extent. be able to.

  However, even if such a configuration is adopted, it is not possible to prevent the tissue specimen collected by the biopsy specimen collecting tool from being contaminated when passing through the treatment instrument insertion channel. In addition, it takes a lot of time to perform pathological diagnosis, and there may be a case where a state where time and human resources cannot be maintained is continued.

  The present invention provides an endoscope for biopsy diagnosis that can completely prevent contamination of a tissue specimen and that can perform processing from tissue specimen collection to staining and pathological diagnosis extremely quickly. For the purpose.

  In order to achieve the above object, the endoscope for biopsy diagnosis according to the present invention has a treatment instrument insertion channel inserted through the entire length of a flexible insertion portion, and a treatment instrument insertion portion at the distal end of the insertion portion. A tissue sample collection unit provided at the distal end of the biopsy sample collection tool that protrudes from the treatment tool projection port, where a treatment tool projection port that is an exit of the biopsy sample collection device inserted through the channel and an observation window are arranged In a biopsy diagnostic endoscope configured to be observed through an observation window, a staining solution absorption holding member is arranged inside the treatment tool protrusion, and a tissue sample collection unit at the tip of the biopsy sample collection tool The tissue specimen collected in the tissue specimen collection part can be stained by bringing the specimen into contact with the staining liquid absorption holding member.

  In addition, the shielding means for shielding the exposed surface of the staining solution absorption holding member in the treatment instrument protrusion is provided movably by an operation from the proximal end side of the insertion portion, and the shielding means is retracted from the shielding position. Thus, the tissue sample collection unit may be brought into contact with the staining solution absorption holding member.

  Then, the shielding means is the distal end portion of the treatment instrument insertion channel, and by pulling the treatment instrument insertion channel from the proximal end side, the distal end portion of the treatment instrument insertion channel moves in the axial direction to the stain solution absorption holding member. You may make it the state which can touch a tissue sample collection part.

  In addition, the staining solution absorption holding member may be made of a sponge material formed in an annular shape, and a biopsy specimen collection tool passed through the treatment instrument insertion channel may pass through the inner hole portion thereof. A staining solution replenishing port for replenishing the holding member with the staining solution from outside the insertion portion may be formed at the distal end of the insertion portion.

  According to the present invention, the staining solution absorption holding member is disposed inside the treatment instrument protrusion, and the tissue sample collection part provided at the tip of the biopsy sample collection tool is brought into contact with the staining solution absorption holding member. Since the tissue specimen collected in the tissue specimen collecting section can be stained, it is possible to perform pathological diagnosis in the body without drawing the tissue specimen into the treatment instrument insertion channel of the endoscope. In addition, contamination of the tissue specimen can be completely prevented, and processing from tissue specimen collection to staining and pathological diagnosis can be performed very quickly.

In the endoscope for biopsy diagnosis which concerns on the Example of this invention, it is side surface sectional drawing of the front-end | tip part in the state in which a tissue sample is dye | stained. It is an external view of the endoscope for biopsy diagnosis which concerns on the Example of this invention. It is a perspective view of the front-end | tip part of the endoscope for biopsy diagnosis which concerns on the Example of this invention. It is side surface sectional drawing of the front-end | tip part of the dyeing impossible state of the endoscope for biopsy diagnosis which concerns on the Example of this invention. It is side surface sectional drawing of the front-end | tip part in the dyeable state of the endoscope for biopsy diagnosis which concerns on the Example of this invention. In the endoscope for biopsy diagnosis which concerns on the Example of this invention, it is side surface sectional drawing of the front-end | tip part in the state from which the tissue sample was extract | collected. 1 is a side cross-sectional view of a distal end portion in a state in which a tissue specimen is observed in a biopsy diagnostic endoscope according to an embodiment of the present invention.

Embodiments of the present invention will be described below with reference to the drawings.
FIG. 2 is an external view of an endoscope for biopsy diagnosis, and the proximal end of the flexible tubular insertion portion 1 is connected to the operation portion 2.

  A treatment instrument insertion channel 3 is inserted through the entire length of the insertion portion 1. The treatment instrument insertion channel 3 includes an insertion movable tube 3i made of a flexible tube movable in the axial direction, and an exterior made of a flexible tube arranged in a state in which the insertion movable tube 3i is loosely inserted. The guide tube 3o is composed of a double tube, the details of which will be described later.

  A distal end body 4 in the form of a block is connected to the distal end of the insertion section 1, and a treatment instrument protrusion as an outlet of the treatment instrument inserted into the treatment instrument insertion channel 3 is connected to the distal end surface 4 a of the distal end section body 4. A mouth 5 and an observation window to be described later are disposed.

  A forceps insertion cap 6 that is an inlet of the treatment instrument insertion channel 3 is disposed so as to protrude in the vicinity of a connection portion between the insertion portion 1 and the operation portion 2 at the lower end portion of the operation portion 2. A channel operation ring 7 having a helicoid mechanism or the like for advancing and retracting the forceps insertion base 6 in the axial direction surrounds the entire circumference of the forceps insertion base 6 so as to be rotatable around the axis. Yes.

  As a result, when the channel operation ring 7 is rotated as indicated by the arrow A, the forceps insertion base 6 moves in the axial direction as indicated by the arrow B, thereby cooperating with the forceps insertion base 6. The distal end portion of the insertion movable tube 3i advances and retreats in the axial direction as indicated by an arrow C.

  3 and 4 are a perspective view and a side sectional view of the distal end portion of the insertion portion 1. As shown in FIG. 3, an illumination window 9 and the like are arranged on the distal end surface 4 a of the distal end main body 4 along with the observation window 8. The objective optical system disposed in the observation window 8 is a so-called front perspective optical system, and an oblique front of the insertion portion 1 is observed as indicated by an arrow V. However, other types of optical systems may be used.

  W shown in FIG. 4 is the range of the observation visual field, and the distal end portion (tissue sample collection portion) of the biopsy sample collection tool protruding in the direction indicated by the arrow S from the treatment tool protrusion 5 passes through the observation window 8. The image is observed through a solid-state imaging device (not shown) provided on the inside thereof.

  A staining solution absorption holding member 11 that absorbs and holds the staining solution is disposed inside the treatment instrument protrusion 5 of the distal end portion main body 4. The staining solution absorption holding member 11 is made of, for example, a ring-shaped sponge material having a water absorption property, and a biopsy specimen collection tool such as a biopsy forceps passed through the treatment instrument insertion channel 3 is used as the staining solution absorption holding member 11. It passes through the inner hole part.

  The distal end portion of the insertion movable tube 3i of the treatment instrument insertion channel 3 is disposed so as to penetrate the inner hole of the staining liquid absorption holding member 11, and the distal end portion of the exterior guide tube 3o is the rear end portion of the distal end portion body 4. It is fixed to.

  As a result, when the channel operation ring 7 is operated on the proximal end side of the treatment instrument insertion channel 3 and the insertion movable tube 3i is pulled in the proximal direction, the insertion movable is performed as shown in FIG. The distal end portion of the tube 3 i moves in the axial direction and retracts to a position behind the staining solution absorption holding member 11, so that the staining solution absorption holding member 11 is exposed in the treatment instrument protruding port 5.

  Therefore, in this state, the tissue sample collected in the tissue sample collection part at the tip of the biopsy sample collection tool is positioned in the inner hole portion of the stain solution absorption holding member 11 so that the stain solution absorption holding member 11 is touched. Can be dyed.

  In addition, when the distal end portion of the insertion movable tube 3i is inserted into the inner hole of the staining solution absorption holding member 11 as shown in FIG. 4, the staining solution absorption holding member 11 is exposed in the treatment instrument protruding port 5. In this state, the biopsy specimen collection tool passes from the treatment instrument insertion channel 3 to the treatment instrument projection port 5 without touching the staining solution absorption holding member 11.

  The tip body 4 is formed with a staining liquid replenishing port 12 penetrating between the outer surface and the outer periphery of the staining liquid absorption holding member 11. The staining solution replenishing port 12 is normally closed with a screw plug or the like, but if opened, the staining solution is injected into the staining solution absorption holding member 11 from outside the insertion portion 1 via the staining solution replenishing port 12. Can be refilled.

  In the biopsy diagnostic endoscope of the embodiment configured as described above, as shown in FIG. 6, the biopsy specimen collection tool 50 is protruded from the treatment instrument projection port 5, and the tissue specimen collection section 51 is in contact with the tissue. When performing an operation of collecting the specimen 100, the insertion movable tube 3i of the treatment instrument insertion channel 3 is advanced to keep the staining liquid absorption holding member 11 in a shielding state.

  When the tissue sample 100 is collected in the tissue sample collection unit 51 of the biopsy sample collection tool 50, the insertion movable tube 3i is retracted backward as shown in FIG. With the inner surface exposed, the tissue specimen 100 is drawn into the treatment instrument projection port 5, and the tissue specimen 100 is brought into contact with the staining solution absorption holding member 11 to be stained.

  Then, as shown in FIG. 7, the tissue sample collection unit 51 of the biopsy sample collection tool 50 is protruded from the treatment tool projection port 5 into the observation field of view by the observation window 8 to observe the stained tissue sample 100. (Close-up magnification observation) and pathological diagnosis can be performed.

  If the objective optical system in the observation window 8 has a close-up magnification capability such as a so-called zoom macro function, a high-level pathological diagnosis can be performed, and if it has a confocal optical system etc., it is as precise as a microscope. Pathological diagnosis can be performed.

  In this way, since the tissue specimen 100 can be collected, stained, and pathologically diagnosed in the body without drawing the tissue specimen 100 into the treatment instrument insertion channel 3, contamination of the tissue specimen 100 and the like can be completely prevented. In addition, processing up to pathological diagnosis can be performed very quickly.

  Note that the present invention relates to an endoscope for biopsy diagnosis, and any biopsy specimen collecting tool 50 may be used, but the tissue specimen 100 is sharply sliced and collected. If the biopsy sample collection tool 50 of the method which can do is employ | adopted, pathological diagnosis capability will improve more.

DESCRIPTION OF SYMBOLS 1 Insertion part 3 Treatment tool insertion channel 3i Interpolation movable tube 3o Exterior guide tube 4 End part main body 5 Treatment tool protrusion 8 Observation window 11 Staining liquid absorption holding member 12 Staining liquid replenishment port 50 Biopsy specimen collection tool 51 Tissue sampling collection 100 tissue specimens

Claims (5)

A treatment instrument insertion channel is inserted and disposed over the entire length in the flexible insertion section, and a treatment instrument projection port which is an outlet of the biopsy specimen collection tool inserted into the treatment instrument insertion channel is provided at the distal end of the insertion section. And an observation window are arranged, and a tissue sample collecting part provided at the tip of the biopsy sample collecting tool protruding from the treatment tool protruding port is configured to be observed through the observation window. In an endoscope,
By arranging a staining solution absorption holding member inside the treatment instrument protruding port and bringing the tissue sample collection portion at the tip of the biopsy sample collection tool into contact with the staining solution absorption holding member, the tissue sample collection portion An endoscope for biopsy diagnosis, characterized in that a tissue sample collected can be stained.   Shielding means for shielding the exposed surface of the staining solution absorption holding member in the treatment instrument protruding port is provided movably by an operation from the proximal end side of the insertion portion, and the shielding means is moved from the shielding position. The endoscope for biopsy diagnosis according to claim 1, wherein the tissue specimen collection part can be brought into contact with the staining liquid absorption holding member by retracting.   The shielding means is the distal end portion of the treatment instrument insertion channel, and the distal end portion of the treatment instrument insertion channel is moved in the axial direction by pulling the treatment instrument insertion channel from the proximal end side, thereby absorbing the staining liquid. The endoscope for biopsy diagnosis according to claim 2, wherein the tissue sample collection part can be brought into contact with a holding member.   The biopsy specimen collection tool passed through the treatment instrument insertion channel passes through the inner hole portion of the staining liquid absorption holding member made of a sponge material formed in an annular shape. An endoscope for biopsy diagnosis according to 1.   The biopsy diagnosis according to any one of claims 1 to 4, wherein a staining liquid replenishing port for replenishing the staining liquid absorption holding member with a staining liquid from outside the insertion portion is formed at a distal end of the insertion portion. Endoscope.

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