JP2010522774A - 血管新生眼疾患を治療するための方法 - Google Patents
血管新生眼疾患を治療するための方法 Download PDFInfo
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- 210000003462 vein Anatomy 0.000 description 1
- 229960003636 vidarabine Drugs 0.000 description 1
- 229960003048 vinblastine Drugs 0.000 description 1
- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
- 229920001567 vinyl ester resin Polymers 0.000 description 1
- 208000029257 vision disease Diseases 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07360012 | 2007-03-30 | ||
| PCT/EP2008/002426 WO2008119500A1 (en) | 2007-03-30 | 2008-03-27 | Methods for treating neovascular ocular diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522774A true JP2010522774A (ja) | 2010-07-08 |
| JP2010522774A5 JP2010522774A5 (cg-RX-API-DMAC7.html) | 2011-05-19 |
Family
ID=39564402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010501409A Pending JP2010522774A (ja) | 2007-03-30 | 2008-03-27 | 血管新生眼疾患を治療するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100233194A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2139492A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010522774A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101678034A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008234141A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2681361A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008119500A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8722015B2 (en) * | 2010-04-01 | 2014-05-13 | The Schepens Eye Research Institute, Inc. | Compositions and methods for treatment of angiogenesis-associated ocular disorders |
| WO2011161295A2 (es) * | 2010-06-23 | 2011-12-29 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Uso de compuestos anticalcineurina para el tratamiento de patologías que cursan con neovascularización ocular |
| MA41818A (fr) * | 2015-03-27 | 2018-01-30 | Leo Pharma As | Timbre à micro-aiguilles pour administration d'un principe actif à la peau |
| US11229662B2 (en) | 2016-11-15 | 2022-01-25 | The Schepens Eye Research Institute, Inc. | Compositions and methods for the treatment of aberrant angiogenesis |
| US11433090B2 (en) | 2017-06-16 | 2022-09-06 | The Doshisha | mTOR-inhibitor-containing medicine for treating or preventing ophthalmic symptoms, disorders, or diseases, and application thereof |
| JP7416700B2 (ja) | 2017-11-14 | 2024-01-17 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | 増殖性硝子体網膜症および上皮間葉転換と関連付けられる状態の治療のためのｒｕｎｘ１阻害の方法 |
| EP3866788B1 (en) * | 2018-10-19 | 2023-12-13 | MediciNova, Inc. | Treatment of macular injury associated with multiple sclerosis with ibudilast |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005110362A1 (en) * | 2004-04-30 | 2005-11-24 | Allergan, Inc. | Biodegradable ocular implants with long-term release characteristics |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| TR200302105T4 (tr) * | 2000-04-07 | 2004-02-23 | Laboratoire Medidom S. A. | Siklosporin, hiyalüronik asit ve polisorbat içeren göz formülasyonları. |
| WO2006039558A2 (en) | 2004-10-09 | 2006-04-13 | Formurex, Inc. | Ocular agent delivery systems |
| US20060148686A1 (en) * | 2004-12-30 | 2006-07-06 | Bausch & Lomb Incorporated | Ophthalmic compositions comprising steroid and cyclosporine for dry eye therapy |
| CA2615990A1 (en) | 2005-07-18 | 2007-01-25 | Minu, L.L.C. | Enhanced ocular neuroprotection/neurostimulation |
| US20070087962A1 (en) * | 2005-10-17 | 2007-04-19 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| DE102006051512A1 (de) * | 2005-12-06 | 2007-06-14 | Pari GmbH Spezialisten für effektive Inhalation | Pharmazeutische Medikamentenzusammensetzungen mit Cyclosporin |
-
2008
- 2008-03-27 JP JP2010501409A patent/JP2010522774A/ja active Pending
- 2008-03-27 EP EP08716704A patent/EP2139492A1/en not_active Withdrawn
- 2008-03-27 US US12/593,758 patent/US20100233194A1/en not_active Abandoned
- 2008-03-27 CA CA002681361A patent/CA2681361A1/en not_active Abandoned
- 2008-03-27 AU AU2008234141A patent/AU2008234141A1/en not_active Abandoned
- 2008-03-27 WO PCT/EP2008/002426 patent/WO2008119500A1/en not_active Ceased
- 2008-03-27 CN CN200880010884A patent/CN101678034A/zh active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005110362A1 (en) * | 2004-04-30 | 2005-11-24 | Allergan, Inc. | Biodegradable ocular implants with long-term release characteristics |
Non-Patent Citations (6)
| Title |
|---|
| JPN5010004576; ＳＡＪＪＡＤＩ Ｈ: ＪＯＵＲＮＡＬ ＯＦ ＯＣＵＬＡＲ ＰＨＡＲＭＡＣＯＬＯＧＹ Ｖ１０ Ｎ３, 19940201, Ｐ５５３-５６０, ＭＡＲＹ ＡＮＮ ＬＩＥＢＥＲＴ ＩＮＣ． ＰＵＢＬＩＳＨＥＲＳ * |
| JPN5010004578; ＲＯＤＲＩＧＵＥＺ-ＡＧＩＲＲＥＴＸＥ Ｉ: ＡＲＣＨＩＶＯＳ ＳＯＣＩＥＤＡＤ ＥＳＰＡＧＮＯＬＡ ＤＥ ＯＦＴＡＬＭＯＬＯＧＩＡ Ｖ７８ Ｎ１, 20030101, Ｐ２９-３４, ＳＯＣＩＥＤＡＤ ＥＳＰＡＧＮＯＬＡ ＤＥ ＯＦＴＡＬＭＯＬＯＧＩＡ * |
| JPN6012056110; ＯＬＩＶＥＲ，Ａ． ｅｔ ａｌ: 'Ｃｏｒｔｉｃｏｓｔｅｒｏｉｄｓ ａｓ ａｎｔｉａｎｇｉｏｇｅｎｉｃ ａｇｅｎｔｓ' Ｏｐｈｔｈａｌｍｏｌ Ｃｌｉｎ Ｎｏｒｔｈ Ａｍ Ｖｏｌ．１９， Ｎｏ．３, 2006, ｐ．３４５-５１ * |
| JPN7012004389; ＲＡＦＩＥＥ，Ｐ． ｅｔ ａｌ: 'Ｃｙｃｌｏｓｐｏｒｉｎ Ａ ｄｉｆｆｅｒｅｎｔｉａｌｌｙ ｉｎｈｉｂｉｔｓ ｍｕｌｔｉｐｌｅ ｓｔｅｐｓ ｉｎ ＶＥＧＦ ｉｎｄｕｃｅｄ ａｎｇｉｏｇｅｎｅｓｉｓ ｉｎ ｈｕｍａｎ ｍｉｃｒｏｖａｓｃ' Ｃｅｌｌ Ｃｏｍｍｕｎ Ｓｉｇｎａｌ Ｖｏｌ．２， Ｎｏ．１, 2004, ｐ．３（１-２２） * |
| JPN7012004390; ＢＨＩＳＩＴＫＵＬ，Ｒ．Ｂ．: 'Ｖａｓｃｕｌａｒ ｅｎｄｏｔｈｅｌｉａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｂｉｏｌｏｇｙ： ｃｌｉｎｉｃａｌ ｉｍｐｌｉｃａｔｉｏｎｓ ｆｏｒ ｏｃｕｌａｒ ｔｒｅａｔｍｅｎｔｓ' Ｂｒ Ｊ Ｏｐｈｔｈａｌｍｏｌ Ｖｏｌ．９０， Ｎｏ．１２, 2006, ｐ．１５４２-７ * |
| JPN7012004391; ＭＵＲＡＴＡ，Ｍ． ｅｔ ａｌ: 'Ｉｎｈｉｂｉｔｏｒｙ ｅｆｆｅｃｔ ｏｆ ｔｒｉａｍｃｉｎｏｌｏｎｅ ａｃｅｔｏｎｉｄｅ ｏｎ ｃｏｒｎｅａｌ ｎｅｏｖａｓｃｕｌａｒｉｚａｔｉｏｎ' Ｇｒａｅｆｅｓ Ａｒｃｈ Ｃｌｉｎ Ｅｘｐ Ｏｐｈｔｈａｌｍｏｌ Ｖｏｌ．２４４， Ｎｏ．２, 2006, ｐ．２０５-９ * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101678034A (zh) | 2010-03-24 |
| WO2008119500A1 (en) | 2008-10-09 |
| AU2008234141A2 (en) | 2009-10-08 |
| EP2139492A1 (en) | 2010-01-06 |
| AU2008234141A1 (en) | 2008-10-09 |
| US20100233194A1 (en) | 2010-09-16 |
| CA2681361A1 (en) | 2008-10-09 |
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