JP2010279455A - Enema container for suspension - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To solve such problems that conventionally, when downward tilting a discharge port of a container body and discharging suspension from an enema nozzle connected to the discharge port, it requires a preparation time till discharging and if the poor-solubility pharmaceutical stagnates at the discharge port of the container body, the discharge operation becomes hard and the thorough prevention of a counter flow is difficult in an enema container for poor-solubility pharmaceutical suspension. <P>SOLUTION: This enema container for suspension includes a valve storage cylinder 1 in a nozzle connection section 61 of an enema nozzle 60 connected to the discharge port 51 of the container body 50 storing the suspension, wherein the valve storage cylinder 1, in its inside, integrally stores a valve member 40 which has a valve head section 10 having a closely-attached side face, and a spiral elastic spring section 30 which elastically presses the valve head section 10 and guides the suspension in the discharge direction. This constitution can fluidly discharge the poor-solubility pharmaceutical suspension from the enema nozzle 60 and surely prevent the counter flow from the enema nozzle side. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  According to the present invention, a suspension of a sparingly soluble drug is discharged from an enema nozzle connected to the discharge port by inclining the discharge port of a container body containing a suspension of the sparingly soluble drug downward. It relates to an enema container for suspension.

  2. Description of the Related Art Conventionally, in an enema container of a suspension in which a hardly soluble drug having a specific gravity heavier than that of a solution is suspended, the discharge port portion of the container body is tilted downward and the poorly soluble drug is suspended from the enema nozzle connected to the discharge port portion. In order to discharge the turbid liquid, since it takes a considerable amount of time to prepare for the discharge after tilting the container body, it may not be possible to perform the discharge operation as if a poorly soluble drug stays in the discharge part of the container body. There was a problem that it was not possible to sufficiently prevent the reverse flow.

  As described in Patent Document 1, the poorly soluble drug used in the present invention has the terms “slightly insoluble”, “hardly soluble”, “very difficult to dissolve” and “mostly insoluble” in Japanese Pharmacopoeia. Those that exhibit any solubility as “not soluble” include those provided as an aqueous suspension.

  As specific examples of poorly soluble drugs, as described in Patent Document 1, steroidal anti-inflammatory agents, anti-inflammatory analgesics, antipyretic analgesics, antiepileptic agents, chemotherapeutic agents, synthetic antibacterial agents, antiviral agents, Examples include hormone agents, angiogenesis inhibitors, immunosuppressants, protease inhibitors, aldose reductase inhibitors, and ulcerative colitis therapeutic agents. Examples of steroidal anti-inflammatory agents include cortisone acetate, betamethasone, prednisolone, fluticasone propionate, dexamethasone, budesonide, beclomethasone propionate, triamcinolone, rotopredonol, fluorometholone, diflupredone, mometasone furocarboxylate, clobetasol propionate, diflorazone acetate, Examples include diflucortron herbate, fluocinonide, amsinonide, harsinonide, fluocinolone acetonide, triamcinolone acetonide, flumethasone pivalate, or clobetasone butyrate. Examples of antipyretic analgesics include acetaminophen or sulpyrine. Examples of the antiepileptic agent include acetazolamide, carbamazepine, clonazepam, diazepam, and nitrazepam. Anti-inflammatory analgesics include, for example, alclofenac, aluminoprofen, ibuprofen, indomethacin, epilysole, oxaprozin, ketoprofen, diclofenac sodium, diflunisal, naproxen, piroxicam, fenbufen, flufenamic acid, flurbiprofen, fructaphenine, pentazocine, methazidic acid, or Examples include mefenamic acid and mofezolac. Chemotherapeutic agents include sulfa drugs such as salazosulfapyridine, sulfadimethoxine, sulfamethizole, sulfamethoxazole, sulfamethopyrazine, or sulfamonomethoxine, enoxin, ofloxacin, sinoxacin, sparfloxacin, Synthetic antibacterial agents such as thianphenicol, nalidixic acid, tosufloxacin tosylate, norfloxacin, pipemidic acid trihydrate, pyromido acid, fleloxacin, or levofloxacin, antiviral agents such as acyclovir, ganciclovir, didanosine, zidovudine, or vitarabine, itraconazole Antifungal agents such as ketoconazole, fluconazole, flucytosine, miconazole, or pimaricin. Examples of the hormone agent include insulin zinc, testosterone propionate, or estradiol benzoate. Examples of the angiogenesis inhibitor include cyclosporine, rapamycin, tacrolimus and the like. Examples of the protease inhibitor include [L-3-trans-ethoxycarbonyloxirane-2-carbonyl] -L-leucine (3-methylbutyl) amide (E-64-d). Examples of aldose reductase inhibitors include 5- (3-ethoxy-4-pentyloxyphenyl) thiazolidine-2,4-dione. Examples of the therapeutic agent for ulcerative colitis include mesalazine.

  In the enema container for suspension described in Patent Document 2, the valve lid is naturally pushed up to 90 degrees according to the fluid pressure of the fluid to be discharged by the open / close lid type valve body hinged to the cylindrical valve body. Although it is configured to be opened, it closes naturally even when it is closed, so that the backflow of fluid cannot be prevented quickly and sufficiently.

JP 2006-36660 A JP 2003-190298 A

  Therefore, the present invention can ensure fluidity without stagnating hardly soluble medicines that do not easily flow in the discharge part of the container main body, and can smoothly discharge and quickly prevent backflow. An object is to provide an enema container for suspension.

  According to the present invention, as described in claim 1, the poorly soluble from the enema nozzle connected to the discharge port portion by tilting the discharge port portion of the container main body containing the suspension in which the hardly soluble drug is suspended. In an enema container that discharges a suspension of a medicine, a large-diameter pipe portion capable of retaining a suspension in a nozzle connecting portion of an enema nozzle that is connected to a discharge port portion of the container body, and the large-diameter A valve receiving tube part that is smoothly reduced in diameter from the pipe part and fitted in close contact with the side surface of the valve head, and a valve housing that smoothly increases the diameter again from the valve receiving pipe part so that the valve head can be opened and closed. A valve housing cylinder having a pipe portion, the valve head having a tapered taper fitting surface on the side surface to be fitted to the valve receiving tube portion in the valve housing cylinder, and a valve housing cylinder A hollow cylindrical valve base that can be installed at the end, and the valve head is pressed between the valve head and the cylindrical valve base toward the valve receiving tube. There is provided a suspension for enema container formed by providing a valve member having a resilient spring portion having a suspension of poorly soluble drugs inducibly spiral discharge direction together.

  Further, according to the present invention, as described in claim 2, in the enema container for suspension according to claim 1, the valve head portion is in close contact with the valve receiving tube portion other than the taper fitting surface. An enema container for suspension which does not have a contact valve portion for guiding and regulating the suspension is provided.

  Further, according to the present invention, as described in claim 3, in the enema container for suspension according to claim 1 or 2, the valve head has a circular cross section from the base end side surface to the tip end side surface and is high. The suspension enema container has a smooth circular cross section in which the radius of the taper fitting surface decreases with a ratio of 0.02 to 0.2 with respect to the thickness.

  Further, according to the present invention, as described in claim 4, in the enema container for suspension according to claim 1, 2, or 3, the valve member is elastic between the valve head and the cylindrical valve base. It is an object of the present invention to provide a suspension enema container that does not have a connecting portion other than a spring portion.

  Further, according to the present invention, as described in claim 5, in the enema container for suspension according to any one of claims 1 to 4, the elastic spring portion includes a plurality of spring pieces that do not overlap each other. An enema container for suspension is provided.

  Further, the present invention provides the suspension enema container according to claim 5, wherein the suspension spring enema container is composed of three spring pieces. It is to provide.

  Further, according to the present invention, as described in claim 7, in the enema container for suspension according to any one of claims 1 to 6, the inner diameter of the elastic spring portion is substantially equal to the inner diameter of the cylindrical valve base portion. An enema container for suspension is provided.

  According to the present invention, as described in claim 8, in the enema container for suspension according to any one of claims 1 to 7, the minimum diameter surface portion of the valve receiving tube portion has a smooth circular cross section. An enema container for suspension is provided.

  Further, according to the present invention, as described in claim 9, the suspension enema container according to any one of claims 1 to 8, wherein the suspension is provided with a recess for preventing backflow in the valve head. A liquid enema container is provided.

  According to the enema container for suspension according to the present invention, as described in claim 1, the present invention has a discharge port portion of a container body containing a suspension in which a poorly soluble drug is suspended downward. In an enema container in which a suspension of a poorly soluble drug is discharged from an enema nozzle that is tilted and connected to the discharge port portion, it is suspended from the nozzle connection portion of the enema nozzle that is connected to the discharge port portion of the container body. A large-diameter pipe part where turbid liquid can stay, a valve-receiving pipe part that is smoothly reduced in diameter from the large-diameter pipe part and is fitted in close contact with the side surface of the valve head, and a large-diameter pipe again from the valve-receiving pipe part. A tapered taper fitting surface which is provided with a valve housing tube having a valve housing tube portion which can be opened and closed so that the valve head can be opened and closed, and is fitted into the valve receiving tube portion in the valve housing tube body. The valve head having a side surface, a hollow cylindrical valve base that can be installed at the end of the valve housing cylinder, the valve head and the cylindrical valve base, It has a configuration in which a valve member having an elastic spring portion provided in a spiral shape so that a valve head is elastically pressed toward a valve receiving tube portion and a suspension of a hardly soluble drug can be guided in a discharge direction. Therefore, when the suspension port of the poorly soluble drug is discharged from the enema nozzle by tilting the discharge port portion of the container body downward, the container body is in close contact with the valve receiving tube portion of the valve housing cylinder provided on the nozzle connection portion. The valve head that had been pushed is pushed into the large-diameter valve housing pipe by the fluid pressure of the suspension, and a liquid flow path that smoothly spreads between the valve head side surface and the valve housing pipe is created. It is swirled in a spiral shape by the elastic spring part in a shape to introduce the suspension into the cylindrical valve base, and the hardly soluble drug that does not flow easily can be fluidly discharged from the enema nozzle without stagnation, When the discharge operation is completed, the valve head pressed by the elastic spring It is guided smoothly and quickly to the valve receiving tube portion, and the tapered fitting surface of the side surface is fitted in a wedge shape on the valve receiving tube portion, so that the backflow from the enema nozzle side can be reliably prevented. .

  Further, according to the present invention, as described in claim 2, in the enema container for suspension according to claim 1, the valve head has a surface other than the smooth tapered fitting surface between the valve receiving tube portion and the valve head portion. Since it does not have a flange-shaped valve part that regulates the contact position, the valve head can be made not only a simple and functional structure that does not hinder the fluidity of the suspension, but also the valve receiving pipe part And the taper fitting surface can be set in a wide range, and the backflow prevention can be reliably prevented.

  Further, according to the present invention, as described in claim 3, in the enema container for suspension according to claim 1 or 2, the valve head has a circular cross section from the base end side surface to the tip end side surface and is high. By adopting a configuration having a smooth circular cross section in which the radius of the taper fitting surface decreases at a rate of 0.02 to 0.2 with respect to the thickness, There is an effect that the close contact position with the taper fitting surface can be set widely and the backflow prevention can be ensured.

  Further, according to the present invention, as described in claim 4, in the enema container for suspension according to claim 1, 2, or 3, the valve member is elastic between the valve head and the cylindrical valve base. By adopting a configuration that does not have a connecting portion other than the spring portion, there is an effect that the fluidity of the suspension can be sufficiently imparted without being disturbed by other structures by the spiral elastic spring portion.

  Further, according to the present invention, as described in claim 5, in the enema container for suspension according to any one of claims 1 to 4, the elastic spring portion includes a plurality of spring pieces that do not overlap each other. By having the configuration, there is an effect that the valve head can be repressed so as to be stably operated by a plurality of spring pieces.

  Further, according to the present invention, as described in claim 6, in the enema container for suspension according to claim 5, the elastic spring portion has a configuration including three spring pieces, so that the valve head There is an effect that the portion can be stably repressed by holding three points.

  Further, according to the present invention, as described in claim 7, in the enema container for suspension according to any one of claims 1 to 6, the inner diameter of the elastic spring portion is substantially equal to the inner diameter of the cylindrical valve base portion. By having the configuration, smooth fluidity of the suspension can be obtained, and when the valve member is integrally molded with plastic, the inner diameter portion can be easily formed with a rod-shaped core having substantially the same diameter. effective.

  According to the present invention, as described in claim 8, in the enema container for suspension according to any one of claims 1 to 7, the minimum diameter surface portion of the valve receiving tube portion has a smooth circular cross section. By having the structure which has, there exists an effect which enables the taper fitting surface of a valve head side surface, and smooth attachment or detachment.

  Further, the present invention provides a suspension enema container according to any one of claims 1 to 8, wherein a backflow-preventing recessed portion is provided on the valve head. By having it, the valve head is pressed by the backflowing liquid, and there is an effect that it is quickly and surely fitted into the valve receiving pipe part.

  The present invention will be described below with reference to the illustrated embodiments.

  As shown in FIG. 7 or FIG. 8, the enema container for suspension according to the present invention tilts the discharge port 51 of the container main body 50 containing the suspension in which the hardly soluble drug is suspended, downwardly. In an enema container 70 in which a suspension of a poorly soluble drug is discharged from an enema nozzle 60 connected to the discharge port portion 51, the nozzle connection portion of the enema nozzle 60 connected to the discharge port portion 51 of the container body 50. 61 is provided with a valve housing cylinder 1 in which the valve member 40 is integrally housed.

  In the valve housing 1, a later-described valve member 40 is integrally housed, and as shown in FIGS. 7 and 8, a tubular nozzle tube of an enema nozzle 60 having a nozzle hole 62 at the tip portion. The nozzle 63 is integrally stored in the nozzle connecting portion 61 near the base of the portion 63.

  The discharge port portion 51 of the container body 50 includes a discharge hole 53 in the center of the container top plate 52, and when the connecting tube portion 65 of the enema nozzle 60 is fitted in a sealed state on the outer periphery thereof, The connecting pipe portion 66 surrounds the discharge hole 53 and is in close contact with the container top plate 52. Reference numeral 64 denotes an elastic clamping tube portion which is constructed so as to get over the discharge port portion 51 and the check projection portion 54 so as not to come off easily. In addition, the structure which the connection cylinder part 65 of the enema nozzle 60 screws together to the discharge outlet part 51 of the container main body 50 may be sufficient.

  As shown in FIG. 2 or FIG. 3, the valve housing cylinder 1 includes a large-diameter pipe portion 2 capable of retaining a suspension supplied from a discharge port portion 51 of a container body 50 inclined downward, and the large-diameter tube portion 2. The valve head 3 can be opened and closed by smoothly reducing the diameter from the pipe section 2 and fitting it in close contact with the side surface of the valve head section 10 and by increasing the diameter smoothly from the valve receiving section 3 again. And a valve housing pipe portion 4 to be housed.

  Further, in the valve housing cylinder 1, the valve head 10 having a tapered taper fitting surface 11 fitted to the valve receiving tube portion 3 on the side surface, and a terminal portion of the valve housing cylinder 1 are installed. A hollow tubular valve base 20 that is possible, and between the valve head 10 and the tubular valve base 20, the valve head 10 is elastically pressed toward the valve receiving tube 3 and a suspension of a hardly soluble drug is applied. A valve member 40 having an elastic spring portion 30 provided in a spiral shape so as to be guided in the discharge direction is provided.

  With this configuration, when the slightly insoluble drug suspension is discharged from the enema nozzle by tilting the discharge port portion of the container body downward, the valve housing provided in the nozzle connecting portion as shown in FIG. The valve head 10 that is in close contact with the valve receiving tube 3 of the cylinder 1 on its side is pushed into the large-diameter valve housing 4 by the fluid pressure of the suspension, and the side of the valve head 10 and the valve housing A liquid flow path A that spreads smoothly between the portions 4 is formed, and then the suspension is swirled by the spiral elastic spring portion 30 to introduce the suspension into the cylindrical valve base 20 and hardly flow. The soluble drug suspension can be fluidly discharged from the enema nozzle without stagnation.

  Further, when the discharge operation is completed, as shown in FIG. 1, the valve head 10 pressed by the elastic spring portion 30 is smoothly and quickly guided from the valve accommodating tube portion 4 to the valve receiving tube portion 3. The taper fitting surface 11 on the side surface is fitted to the valve receiving tube portion 3 in a wedge shape, so that backflow from the enema nozzle side can be reliably prevented. This means that the backflow from the enema nozzle side can be reliably prevented even when the enema nozzle is inserted into the intestine before the discharge operation or the like. A backflow prevention recess 13 is provided on the back side of the valve head 10 so that the valve head 10 is pressed by the backflowing liquid so that the valve head 10 can be quickly and reliably fitted to the valve receiving tube 3. It is.

  As shown in FIG. 2, the valve receiving tube portion 3 is fitted to a tapered diameter surface portion 3 b that smoothly decreases in diameter from the large diameter tube portion 2 and a tapered fitting surface 11 on the side surface of the valve head 10. The small-diameter surface portion 3a and the large-diameter taper surface 3c that smoothly increases the diameter again, and the small-diameter taper surface portion 3b smoothly guides the suspension to be discharged from the large-diameter pipe portion 2 to the valve head 10 to provide a valve. The head 10 can be quickly detached, the smallest diameter surface portion 3a having a smooth circular cross section enables smooth attachment and detachment with the taper fitting surface 11 on the side surface of the valve head, and the increased diameter tapered surface 3c is the valve head. The liquid flow path A that smoothly spreads between the upper side surface of the valve 10 and the valve accommodating pipe portion 4 is formed, thereby improving the suspension flow.

  Further, since the valve head 10 has no flange-like valve portion for regulating the contact position other than the smooth taper fitting surface 11 between the valve head 10 and the valve receiving tube portion 3, the valve head 10 is suspended. Not only can a simple and functional structure not hinder the fluidity of the turbid liquid, but also the contact position between the valve receiver 3 and the taper fitting surface 11 can be set widely to ensure backflow prevention. Can do. Reference numeral 12 denotes an arcuate surface portion provided between the top surface portion 14 of the valve head 10 and the taper fitting surface 11.

  In addition, the valve head 10 has a circular shape in cross section from the base end side surface to the tip end side surface, and the radius of the taper fitting surface 11 decreases with a ratio of approximately 0.02 to 0.2 with respect to the height. 2, it is possible to set a wide contact position between the valve receiving tube portion 3 and the taper fitting surface 11 corresponding to the fluidity of the suspension, and as shown in FIG. The liquid flow path B with the pipe part 4 is smoothly narrowed to increase the flow pressure, and the liquid flow path C is widened to the wide liquid flow path C in the circular pipe part 21 in the cylindrical valve base 20 via the hollow helical spring 30. The poorly soluble drug that is difficult to flow can be introduced and fluidly discharged from the enema nozzle without stagnation. In the case of the illustrated embodiment, the valve head 10 is circular in cross section from the base end side surface to the tip end side surface, and the radius of the taper fitting surface 11 decreases with a ratio of approximately 0.1 with respect to the height. Has a circular cross section.

  Further, the valve housing cylinder 1 includes a locking step portion 5 for locking the cylindrical valve base portion 20 to the lower end portion of the valve housing pipe portion 4, and an engagement edge provided outside the cylindrical valve base portion 20. The part 22 is configured to be fitted in from the bottom in the drawing. In this case, the minimum diameter portion of the locking step portion 5 is substantially equal to the outer diameter of the side surface of the base end portion of the valve head portion 10, and therefore the outer shape of the engagement edge portion 22 is smaller than the valve accommodating tube portion 4 and has a locking step. It is configured to be larger than the minimum diameter portion of the portion 5, and is configured to be elastically fitted through a guide tube portion 6 provided with a smoothly enlarged diameter below the locking step portion 5 in the drawing. . A fitting recess 23 that fits into the guide tube portion 6 is provided below the engagement edge portion 22 of the tubular valve base portion 20.

  Further, in the drawing, the spiral elastic spring portion 30 according to the present invention is an elongated spring piece portion between the lower outer edge portion 15 of the valve head 10 and the upper outer edge portion 24 of the tubular valve base portion 20. 31 is provided in a spiral, and a spiral liquid flow path is formed between the spring pieces 31 even in a compressed state as shown in FIG. The spring piece portion 31 may be formed by winding a single spring piece portion 31 one or more times like a coil spring, or two or more multiple spring piece portions 31 so as not to overlap each other. It is also possible to adopt a spiral form.

  In the case of the embodiment shown in FIG. 3, three spring pieces 31 are provided so as to be spiraled by turning 120 degrees at intervals of 120 degrees, and the valve head 10 is provided with three spring pieces 31. It is configured so that the three points can be stably repressed.

  The individual spring piece portions 31 are provided so as to be wound around the virtual cylindrical portion 32 as if the virtual inner cylindrical portion 32 existed. In the illustrated embodiment, the inner side surface 33 of the spring piece portion 31 is planar. The outer surface 34 is shaped so that the cross section is a triangular or arcuate mountain shape, and the spiral flow path formed by the spring piece portion 31 easily flows from the outside to the inside. It is difficult to return from the inside to the outside. Needless to say, the elastic spring portion 30 composed of one, two, four or more spring piece portions 31 can be similarly configured.

  The valve member 40 having the above-described configuration can be integrally processed by plastic injection molding. The tip of the rod-shaped core having the same diameter as the diameter of the virtual inner cylindrical portion 32 of the elastic spring portion 30 and the diameter of the circular tube portion 21 of the cylindrical valve base 20 is connected to the concave portion for backflow prevention of the valve head 10. 13 is covered with a split mold whose cavity matches the outer shape of the valve head 10, the elastic spring 30 and the tubular valve base 20, and the molten plastic is filled into the cavity from the gate. If the outer mold and the core are removed after the plastic is solidified, the valve member 40 can be integrally formed.

  The valve housing cylinder 1 can also be processed with plastics.

The partial schematic sectional drawing which shows the one operation mode of the principal part of this invention Example. The partial schematic sectional drawing which shows the other action | operation aspect of the principal part. The front view of the principal part. The plan view. The plan view. The center longitudinal cross-sectional view of the principal part of FIG. 1 is a schematic sectional view of an embodiment of the present invention. The partial decomposition schematic sectional drawing of the Example.

DESCRIPTION OF SYMBOLS 1 Valve accommodating cylinder 2 Large diameter pipe part 3 Valve receiving pipe part 4 Valve accommodating pipe part 5 Locking step part 6 Guide cylinder part 10 Valve head part 11 Taper fitting surface 12 Arc surface part 13 Backflow prevention recessed part 14 Top surface part 15 Lower outer edge portion 20 Cylindrical base portion 21 Circular tube portion 22 Engagement edge portion 23 Fitting recess 24 Upper outer edge portion 30 Elastic spring portion 31 Spring piece portion 32 Virtual inner cylindrical portion 33 Inner side surface 34 Outer side surface 40 Valve member 50 Container body 51 Discharge port 60 Enema nozzle 61 Nozzle connection portion 62 Nozzle hole 63 Nozzle tube portion 64 Clamping tube portion 65 Connection tube portion 66 Connection tube portion 70 Enema container

Claims (9)

An enema in which a suspension of a sparingly soluble drug is discharged from an enema nozzle connected to the discharge port by tilting the discharge port of a container body containing a suspension of the sparingly soluble drug downward In the container,
A large-diameter pipe part where suspension can stay in the nozzle connection part of the enema nozzle that is connected to the discharge port part of the container body, and a small diameter smoothly from the large-diameter pipe part to make close contact with the side surface of the valve head And a valve receiving tube having a valve receiving pipe that is fitted and received, and a valve receiving pipe that accommodates the valve head so that the valve head can be opened and closed smoothly.
In the valve housing cylinder, the valve head having a tapered taper fitting surface on the side surface that fits the valve receiving tube portion, and a hollow cylindrical valve base that can be installed at the end of the valve housing cylinder And a spring portion provided in a spiral shape between the valve head and the tubular valve base so that the valve head is elastically pressed toward the valve receiving tube and the suspension of the hardly soluble drug can be guided in the discharge direction. A suspension enema container provided with a valve member having   2. The suspension enema container according to claim 1, wherein the valve head has a contact valve portion that guides and regulates the contact position other than the taper fitting surface between the valve head portion and the valve receiving tube portion. Enema container.   The suspension enema container according to claim 1 or 2, wherein the valve head has a circular cross-section from the base end side surface to the tip end side surface and the radius of the taper fitting surface with respect to the height is 0.02 to 0.02. An enema container for suspension having a smooth circular cross section decreasing at a rate of 0.2.   The suspension enema according to claim 1, 2, or 3, wherein the valve member does not have a connecting portion other than the elastic spring portion between the valve head portion and the tubular valve base portion. container.   The suspension enema container according to any one of claims 1 to 4, wherein the elastic spring portion is composed of a plurality of spring pieces that do not overlap each other.   6. The enema container for suspension according to claim 5, wherein the elastic spring part is composed of three spring pieces.   The suspension enema container according to any one of claims 1 to 6, wherein the inner diameter of the elastic spring portion is substantially equal to the inner diameter of the cylindrical valve base.   The suspension enema container according to any one of claims 1 to 7, wherein the minimum diameter surface portion of the valve receiving tube portion has a smooth arc cross section.   The suspension enema container according to any one of claims 1 to 8, wherein a recess for preventing backflow is provided in a valve head.

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