JP2010207318A - Living tissue collecting apparatus - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To efficiently sample living tissues from a living body while precisely measuring the amount of living tissue. <P>SOLUTION: There is provided a living tissue collecting apparatus 1 including: a tissue collecting portion 3 for collecting the living tissue from inside the body; a container 2 for storing the living tissue collected by the tissue collecting portion 3; a motor 4b for accelerating or decelerating the container 2 from a first rotational speed up to a second rotational speed at a prescribed acceleration; a current measurement portion 5 for measuring current flowing in a motor 4b in accelerating or decelerating the container 2 by the motor 4b; and a weight calculation portion 6 for calculating weight of the living tissue in the container 2 on the basis of the current measured by the current measurement portion 5. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a biological tissue collection device.

  Conventionally, a technique for separating fat-derived cells such as stem cells from adipose tissue collected from the body is known (see, for example, Patent Document 1). As a method for collecting adipose tissue, a method of sucking with a cannula or the like is used.

JP 2005-519883 Gazette

  When adipose-derived cells are separated from the collected adipose tissue and used for medical treatment, it is not preferable to remove the adipose tissue once accommodated in the container for reasons of maintaining sterility and the necessary amount of adipose tissue. There is a demand to just accurately collect in the container. However, since the apparatus used for conventional liposuction is designed for the purpose of removing adipose tissue from the body, it is not necessary to accurately detect the amount of suction and does not have such a function.

  Also, when trying to measure the amount of sucked adipose tissue from the increase in the weight of the container using a weigh scale, the container is vibrated by the fat tissue injected into the container one after another and the weight is accurately measured. Can not do it. Therefore, the suction must be stopped every time the weight of the adipose tissue is measured, and there is a problem that the work efficiency is poor.

  The present invention has been made in view of the above-described circumstances, and an object of the present invention is to provide a living tissue collection apparatus that can efficiently collect living tissue from a living body while accurately measuring the amount of living tissue. It is said.

In order to achieve the above object, the present invention provides the following means.
The present invention includes a tissue collection unit that collects a biological tissue from the body, a container that stores the biological tissue collected by the tissue collection unit, and a second rotation speed from the first rotation speed to the container at a predetermined acceleration. A motor for accelerating or decelerating, a current measuring unit for measuring a current flowing through the motor when the container is accelerated or decelerated by the motor, and a living tissue in the container based on the current measured by the current measuring unit Provided is a biological tissue collection device including a weight calculation unit that calculates weight.

According to the present invention, when a biological tissue is collected from the body by the tissue collecting unit, the biological tissue is accommodated in the container and can be collected.
In this case, if a biological tissue is collected while the container is accelerated or decelerated at a predetermined speed by a motor with a predetermined acceleration, the load applied to the motor increases with an increase in the weight of the container, and the current flowing through the motor increases. . That is, the weight of the living tissue in the container is measured from the weight increase calculated by the calculation unit based on the current measured by the current measurement unit.

  In this way, by measuring the weight of the container based on the current flowing through the motor, while accurately measuring the amount of the biological tissue collected in the container without being affected by the vibration of the container, the biological tissue is removed from the living body. It can be collected efficiently.

In the above invention, the current measured by the current measuring unit may be a starting current when the motor is accelerated from a stopped state to a predetermined rotational speed.
By doing in this way, control of a motor can be made easy.

Further, in the above invention, the apparatus includes a base that is disposed substantially horizontally and on which the container is placed, and the motor follows the predetermined circumferential orbit in a substantially horizontal plane while maintaining the posture of the base. It is good also as carrying out translation rotation.
By doing in this way, the weight of the biological tissue extract | collected using the structure with which the conventional shaker is equipped can be measured.

  According to the present invention, it is possible to efficiently collect a living tissue from a living body while accurately measuring the amount of the living tissue.

1 is an overall configuration diagram of a biological tissue collection device according to an embodiment of the present invention. It is a figure explaining operation | movement of a motor. It is a figure which shows the modification of a container.

A biological tissue collection device 1 according to an embodiment of the present invention will be described below with reference to FIGS.
In the present embodiment, a case where adipose tissue is aspirated and collected from the body will be described as an example.

  As shown in FIG. 1, the biological tissue collection apparatus 1 according to the present embodiment includes a container 2 that contains adipose tissue, a cannula (tissue collection unit) 3 in which a suction tube 3 a is connected to the container 2, and a container 2 and a shaker 4 having a motor 4b that translates and rotates the base 4a, a current measuring unit 5 that measures a current flowing through the motor 4b, and a weight of fat tissue. And a weight calculation unit 6 for display.

The container 2 has a cylindrical shape. A lid 2a having a sealed upper part is provided with an inlet 2b and an exhaust port 2c connected to the exhaust pump 7.
When the exhaust pump 7 is operated, the inside of the container 2, the suction tube 3 a and the cannula 3 is depressurized and sucked into the container 2 from the suction port 3 b opened at the tip of the cannula 3.

The base 4a is circular and is disposed substantially horizontally. In addition, a side wall 4c is provided above the base 4a along the outer periphery so that the bottom and side surfaces of the container 2 placed on the base 4a are supported.
The motor 4b has a rotation shaft 4d fixed perpendicularly to the approximate center of the base 4a, and translates the rotation shaft 4d along a predetermined circumferential orbit in a horizontal plane. As a result, when the motor 4b is driven, the base 4a is translated and rotated around a predetermined vertical eccentric axis while maintaining the posture, and the contents in the container 2 are agitated.

  In addition to the operation of rotating the base 4a at a constant speed, the motor 4b performs acceleration at a predetermined acceleration from a stopped state to a predetermined rotation speed as shown in FIG. It is designed to drive repeatedly. At this time, the time interval of the cycle is set sufficiently long with respect to the time required for acceleration so that the next acceleration is started after the base 4a driven to a predetermined rotational speed is sufficiently stopped. Yes.

When the weight of the contents in the container 2 changes, the load applied to the motor 4b when the container 2 is accelerated at a predetermined acceleration changes. Therefore, the driving force required for the motor 4b to accelerate the container 2, that is, The current flowing through the motor 4b changes in proportion to the weight of the contents.
When the rotation is accelerated at a predetermined acceleration, a substantially constant current flows through the motor 4b.

The current measuring unit 5 measures the starting current that flows to the motor 4 b when the motor 4 b accelerates from a stopped state to a predetermined speed, and outputs the measured starting current to the weight calculating unit 6.
The weight calculation unit 6 stores a function for calculating the weight of the adipose tissue stored in the container 2 from the current value input from the current measurement unit 5, and from the starting current input according to the function, The weight is calculated, and the calculated weight is displayed on the panel 6a. The function is obtained experimentally, for example, by measuring the current that flows through the motor 4b when the container 2 having a known weight is placed on the base 4a and accelerated at a predetermined acceleration. Alternatively, the function is obtained from design values such as the characteristics of the load and current of the motor 4b.

The operation of the biological tissue collecting apparatus 1 configured as described above will be described below.
In order to collect adipose tissue from the body using the biological tissue collection apparatus 1 according to the present embodiment, the tip of the cannula 3 is inserted into the adipose tissue site of the patient. When the exhaust pump 7 is operated while driving the motor 4 b to intermittently accelerate the container 2, the adipose tissue is sucked from the suction port 3 b and stored in the container 2. The operator monitors the weight of the fat tissue displayed on the panel 6a while operating the cannula 3 and stops the exhaust pump 7 when the desired weight is reached. Can be collected.

  As described above, according to the present embodiment, the weight of the fat tissue stored in the container 2 is measured based on the starting current of the motor 4b, so that the vibration of the container 2 can be performed even while sucking the fat tissue. There is an advantage that the weight of the adipose tissue can be accurately measured without being affected by the above. In addition, this eliminates the need to stop aspiration of the adipose tissue, so that there is an advantage that the time required for aspiration of the adipose tissue can be shortened and efficiency can be improved. Further, the amount of adipose tissue collected is measured in real time, and the operator can easily collect only a desired amount of adipose tissue in the container 2 while recognizing the current adipose tissue weight. There is.

Further, since the weight of the adipose tissue is measured using a configuration provided in a conventional shaker, it can be easily realized with a simple configuration.
Further, by rotating the container 2 in translation, the suction tube 3a can be prevented from being twisted even when the suction tube 3a is connected to the container 2, and the weight can be measured without hindering the suction operation by the cannula 3. Can do.

In the above-described embodiment, the current during acceleration of the motor 4b is measured, but instead, the current during deceleration of the motor 4b may be measured.
When the rotation of the motor 4b is decelerated at a predetermined acceleration, the load applied to the motor 4b and the current flowing through the motor 4b change in proportion to the weight of the container 2 as in the acceleration. Therefore, for example, the weight of the adipose tissue can also be measured by measuring the current of the motor 4b when the motor 4b is decelerated from a predetermined rotational speed to the stop state.

In the above invention, the motor 4b is accelerated from the stopped state to a predetermined rotational speed and the starting current of the motor 4b is measured. Instead, from a constant rotational speed (first rotational speed). The current of the motor 4b when the motor is accelerated to a predetermined rotational speed (second rotational speed) faster than the rotational speed may be measured.
By doing in this way, the weight of these can be measured simultaneously, stirring a thing, for example, a fat tissue, and the process liquid which processes this fat tissue in the container 2. FIG.

Moreover, in the said invention, the container 2 may be equipped with the discharge port 2d opened to the bottom face 2f, and the filter 2e which covers this discharge port 2d inside and prohibits passage of fat tissue.
For example, as shown in FIG. 3, the bottom surface 2f of the container 2 is inclined in one direction, the discharge port 2d is opened at the lowest position, and the semicircular filter 2e is disposed above the discharge port 2d. It is arranged substantially horizontally while sealing the gap with the. Further, in this case, for example, an opening is provided in a part of the base 4 a and a drain tube 8 extending from the discharge port 2 d to the outside is connected to allow the liquid to be discharged from the container 2.

  As a technique for aspirating adipose tissue from the body, a tubular method using a tubular solution in which an anesthetic or hemostatic agent is added to physiological saline is known. Since the adipose tissue is bonded to each other in the body, the tumescent liquid is injected into the adipose tissue site to swell the adipose tissue, and is softened and then sucked at the same time as the tumescent liquid. In addition, the tumecent liquid sucked in this manner and contained in the container 2 is contained in the partially swollen adipose tissue, but most of it is separated from the adipose tissue and lower than the adipose tissue due to the difference in specific gravity. Accumulate.

  Accordingly, by providing the discharge port 2d on the bottom surface 2f and holding the adipose tissue at a position away from the discharge port 2d by the filter 2e, of the adipose tissue and the tumecent solution injected from the injection port 2b, It is discharged from the discharge port 2d. By doing in this way, when a fat tissue is extract | collected using the Tumecent method, the weight of the fat tissue accommodated in the container 2 can be measured more correctly.

DESCRIPTION OF SYMBOLS 1 Biological tissue sampling device 2 Container 2a Lid 2b Inlet 2c Exhaust port 2d Exhaust port 2e Filter 2f Bottom surface 3 Cannula (tissue sampling part)
3a Suction tube 3b Suction port 4 Shaker 4a Base 4b Motor 4c Side wall 4d Rotating shaft 5 Current measurement unit 6 Weight calculation unit 6a Panel 7 Exhaust pump 8 Drain tube

Claims (3)

A tissue collection unit for collecting biological tissue from the body;
A container for storing a biological tissue collected by the tissue collection unit;
A motor that accelerates or decelerates the container from a first rotational speed to a second rotational speed at a predetermined acceleration;
A current measuring unit for measuring a current flowing through the motor when the container is accelerated or decelerated by the motor;
A biological tissue collection device comprising: a weight calculation unit that calculates the weight of the biological tissue in the container based on the current measured by the current measurement unit.   The living tissue sampling apparatus according to claim 1, wherein the current measured by the current measuring unit is a starting current when the motor is accelerated from a stopped state to a predetermined rotation speed. A substantially horizontal arrangement, comprising a base on which the container is placed;
The biological tissue collection device according to claim 1, wherein the motor translates and rotates the base along a predetermined circumferential trajectory in a substantially horizontal plane while maintaining its posture.

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