JP2010090195A - 固形石鹸及びこれを用いた送達方法 - Google Patents
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Abstract
【解決手段】本発明の固形石鹸は、耐アルカリ性を有しない微生物培養物と、この微生物培養物を被覆しているゼラチン層と、このゼラチン層に外接している石鹸本体とを備えている。上記微生物は少なくとも乳酸菌を含むことが好ましい。一対のゼラチン層間に微生物培養物を積層した層状体が石鹸本体を少なくとも二片に分断するように配設されているとよい。本発明の固形石鹸を利用した送達方法は、微生物の体表面への送達方法であり、活性を有した状態で微生物を体表面に送達することを特徴とする。
【選択図】図1
Description
耐アルカリ性を有しない微生物培養物と、
この微生物培養物を被覆しているゼラチン層と、
このゼラチン層に外接している石鹸本体と
を備える固形石鹸である。
微生物の体表面への送達方法であって、
上記固形石鹸を用いて体表面を洗浄することで、活性を有した状態で微生物を体表面に送達することを特徴とする送達方法である。
(1)層状体3又は粒状体12が露出している固形石鹸(1又は11)の表面と送達箇所とを直接接触させる方法、
(2)層状体3又は粒状体12が露出している固形石鹸(1又は11)の表面をバススポンジ等の洗浄器具と接触させて、乳酸菌培養物4を洗浄器具に付着させたうえで、この洗浄器具と送達箇所とを接触させる方法等を挙げることができる。
使用する材料(括弧内は重量%)
牛脂(22.4)
ヤシ油(11.3)
ヒマシ油(2.4)
ラウリン酸(1.6)
ミリスチン酸(2.7)
パルミチン酸(2.5)
エタノール(21.4)
水酸化ナトリウム(6.9)
蒸留水(11.7)
砂糖(13.5)
ソルビット液(3.6)
一対のダイロール間に二枚のゼラチンシートを供給し、その上から乳酸菌(ラクトバチルス・ブルガリクス及びラクトバチルス・アシドフィラス)培養物を供給した。さらに、ダイロールにおける成形突起の作用によってこの乳酸菌培養物をゼラチンシートによって包み込み、長径12.8mm、短径8.1mm、比重1.2の長楕円型の粒状体を得た。上記実施例1と同様の手順で得た石鹸膠に対して、分散濃度30質量%の割合で粒状体を添加し、ほぼ均一に分散させたうえで枠に流し込んで冷却固化させた。ここで、各粒状体の比重が1.2であり石鹸膠との比重差が小さいため、各粒状体を石鹸膠中において均一に分散させることができた。冷却固化後に枠から抜き、縦5.5cm、横8.0cm、高さ2.55cmの寸法に切断したうえ乾燥させて整形し、固形石鹸を得た。
使用する材料(括弧内は重量%)
オリーブ油(68.2)
水酸化ナトリウム(7.9)
蒸留水(23.9)
上記実施例1と同様の手順で得た石鹸膠を枠に流し込んで冷却固化させ、この固化後に枠から抜き、縦5.5cm、横8.0cm、高さ2.55cmの寸法に切断したうえ乾燥させて整形し、固形石鹸を得た。
上記実施例1〜3、及び比較例1の固形石鹸に基づいて、専門パネラーにより、1日1回30日間継続して使用した場合の使用性評価を行った。
2 石鹸本体
3 層状体
4 乳酸菌培養物
5 ゼラチン層
11 固形石鹸
12 粒状体
Claims (6)
- 耐アルカリ性を有しない微生物培養物と、
この微生物培養物を被覆しているゼラチン層と、
このゼラチン層に外接している石鹸本体と
を備える固形石鹸。 - 上記微生物は少なくとも乳酸菌を含む請求項1に記載の固形石鹸。
- 一対のゼラチン層間に微生物培養物を積層した層状体が石鹸本体を少なくと二片に分断するように配設されている請求項1又は請求項2に記載の固形石鹸。
- 固形石鹸が扁平な略四角柱状体又は略円柱状体であり、
上記層状体が、固形石鹸の上下面に対して平行又は垂直に形成されている請求項3に記載の固形石鹸。 - カプセル状のゼラチン層内に微生物培養物を封入した複数の粒状体が石鹸本体内に分されている請求項1又は請求項2に記載の固形石鹸。
- 微生物の体表面への送達方法であって、
請求項1から請求項5のいずれか1項に記載の固形石鹸を用いて体表面を洗浄することで、活性を有した状態で微生物を体表面に送達することを特徴とする送達方法。
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Cited By (2)
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WO2010143723A1 (ja) * | 2009-06-13 | 2010-12-16 | 尾関 幸一 | 石鹸及びその製造方法 |
WO2012104025A3 (de) * | 2011-01-31 | 2013-01-17 | Merz Pharma Gmbh & Co. Kgaa | Balneologische lipidhaltige probiotische zubereitungen und deren anwendungen |
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JPS62599A (ja) * | 1985-06-27 | 1987-01-06 | ライオン株式会社 | 固型石けん組成物 |
JPH0860198A (ja) * | 1994-08-22 | 1996-03-05 | Sanwa Kagaku Kenkyusho Co Ltd | 多層形状固形石鹸 |
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WO2010143723A1 (ja) * | 2009-06-13 | 2010-12-16 | 尾関 幸一 | 石鹸及びその製造方法 |
JP2010285566A (ja) * | 2009-06-13 | 2010-12-24 | Ozeki Koichi | 石鹸及びその製造方法 |
WO2012104025A3 (de) * | 2011-01-31 | 2013-01-17 | Merz Pharma Gmbh & Co. Kgaa | Balneologische lipidhaltige probiotische zubereitungen und deren anwendungen |
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