JP2009536181A - 癌治療用の18,21−ジデスオキシマクベシン誘導体 - Google Patents

癌治療用の18,21−ジデスオキシマクベシン誘導体 Download PDF

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Publication number
JP2009536181A
JP2009536181A JP2009508383A JP2009508383A JP2009536181A JP 2009536181 A JP2009536181 A JP 2009536181A JP 2009508383 A JP2009508383 A JP 2009508383A JP 2009508383 A JP2009508383 A JP 2009508383A JP 2009536181 A JP2009536181 A JP 2009536181A
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Japan
Prior art keywords
strain
compound
represent
pharmaceutically acceptable
didesoxymacbecin
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Abandoned
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JP2009508383A
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English (en)
Japanese (ja)
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JP2009536181A5 (enExample
Inventor
マルチン クフリスチネ
ズハング ミング
コアテス ニゲル
ボウスデン ウィルリアム
モスス ステベン
ガイスセル サビネ
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バイオチカ テクノロジー リミテッド
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Publication date
Priority claimed from GBGB0609132.6A external-priority patent/GB0609132D0/en
Priority claimed from GB0616637A external-priority patent/GB0616637D0/en
Priority claimed from GBGB0622341.6A external-priority patent/GB0622341D0/en
Application filed by バイオチカ テクノロジー リミテッド filed Critical バイオチカ テクノロジー リミテッド
Publication of JP2009536181A publication Critical patent/JP2009536181A/ja
Publication of JP2009536181A5 publication Critical patent/JP2009536181A5/ja
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009508383A 2006-05-09 2007-05-09 癌治療用の18,21−ジデスオキシマクベシン誘導体 Abandoned JP2009536181A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0609132.6A GB0609132D0 (en) 2006-05-09 2006-05-09 Novel compounds and methods for their production
GB0616637A GB0616637D0 (en) 2006-08-22 2006-08-22 Novel compounds and methods for their production
GBGB0622341.6A GB0622341D0 (en) 2006-11-09 2006-11-09 Novel compounds and methods for their preparation
PCT/EP2007/054476 WO2007128829A2 (en) 2006-05-09 2007-05-09 18,21-didesoxymacbecin derivatives for the treatment of cancer

Publications (2)

Publication Number Publication Date
JP2009536181A true JP2009536181A (ja) 2009-10-08
JP2009536181A5 JP2009536181A5 (enExample) 2010-07-01

Family

ID=38476939

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009508383A Abandoned JP2009536181A (ja) 2006-05-09 2007-05-09 癌治療用の18,21−ジデスオキシマクベシン誘導体

Country Status (9)

Country Link
US (1) US20090253667A1 (enExample)
EP (1) EP1928837A2 (enExample)
JP (1) JP2009536181A (enExample)
KR (1) KR20090005376A (enExample)
AU (1) AU2007247121A1 (enExample)
BR (1) BRPI0711093A2 (enExample)
CA (1) CA2651558A1 (enExample)
MX (1) MX2008014278A (enExample)
WO (1) WO2007128829A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110160175A1 (en) * 2006-09-11 2011-06-30 Christine Martin 18,21-Didesoxymacbecin Derivatives for the Treatment of Cancer
JP2010516282A (ja) 2007-01-26 2010-05-20 コーサン バイオサイエンシーズ, インコーポレイテッド 工学的生合成によるマクロラクタム
CA2679224A1 (en) * 2007-03-01 2008-09-04 Biotica Technology Limited Novel compounds
AR077405A1 (es) 2009-07-10 2011-08-24 Sanofi Aventis Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer
FR2949467B1 (fr) 2009-09-03 2011-11-25 Sanofi Aventis Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation
CN101869138B (zh) * 2010-05-28 2012-05-30 江苏省农业科学院 一种微胶囊发酵剂储存保护液

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241754B2 (en) * 2003-06-13 2007-07-10 Kosan Biosciences, Inc. 2-Desmethyl ansamycin compounds
CA2628728A1 (en) * 2005-12-24 2007-07-05 Biotica Technology Ltd. 21-deoxymacbecin analogues useful as antitumor agents

Also Published As

Publication number Publication date
CA2651558A1 (en) 2007-11-15
BRPI0711093A2 (pt) 2011-08-23
WO2007128829A3 (en) 2008-01-03
MX2008014278A (es) 2008-11-26
KR20090005376A (ko) 2009-01-13
US20090253667A1 (en) 2009-10-08
EP1928837A2 (en) 2008-06-11
AU2007247121A1 (en) 2007-11-15
WO2007128829A2 (en) 2007-11-15

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