JP2009503072A - 退形成性神経膠腫に対する補助的化学療法 - Google Patents

退形成性神経膠腫に対する補助的化学療法 Download PDF

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Publication number
JP2009503072A
JP2009503072A JP2008525035A JP2008525035A JP2009503072A JP 2009503072 A JP2009503072 A JP 2009503072A JP 2008525035 A JP2008525035 A JP 2008525035A JP 2008525035 A JP2008525035 A JP 2008525035A JP 2009503072 A JP2009503072 A JP 2009503072A
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Japan
Prior art keywords
glioma
tert
pbn
butylnitrone
tumor
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JP2008525035A
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English (en)
Japanese (ja)
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JP2009503072A5 (enExample
Inventor
レアル エー. タウナー
ヤシゲ コタケ
ロバート エー. フロイド
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Oklahoma Medical Research Foundation
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Oklahoma Medical Research Foundation
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Publication of JP2009503072A publication Critical patent/JP2009503072A/ja
Publication of JP2009503072A5 publication Critical patent/JP2009503072A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008525035A 2005-08-04 2006-07-28 退形成性神経膠腫に対する補助的化学療法 Withdrawn JP2009503072A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70572105P 2005-08-04 2005-08-04
PCT/US2006/029152 WO2007019065A2 (en) 2005-08-04 2006-07-28 Adjuvant chemotherapy for anaplastic gliomas

Publications (2)

Publication Number Publication Date
JP2009503072A true JP2009503072A (ja) 2009-01-29
JP2009503072A5 JP2009503072A5 (enExample) 2009-09-10

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ID=37727837

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008525035A Withdrawn JP2009503072A (ja) 2005-08-04 2006-07-28 退形成性神経膠腫に対する補助的化学療法

Country Status (6)

Country Link
US (1) US20070032453A1 (enExample)
EP (1) EP1922075A4 (enExample)
JP (1) JP2009503072A (enExample)
AU (1) AU2006278741A1 (enExample)
CA (1) CA2617492A1 (enExample)
WO (1) WO2007019065A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003262642B2 (en) 2002-08-14 2010-06-17 Vertex Pharmaceuticals Incorporated Protein kinase inhibitors and uses thereof
US7723301B2 (en) * 2007-08-29 2010-05-25 The Board Of Trustees Of The University Of Arkansas Pharmaceutical compositions comprising an anti-teratogenic compound and applications of the same
CA2735859C (en) 2008-09-02 2016-08-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl tert-butyl nitrone for the treatment of gliomas
JP5242651B2 (ja) * 2010-09-24 2013-07-24 株式会社東芝 レポーター遺伝子構築物、アッセイキットおよび検出方法
CN111132672A (zh) 2017-09-20 2020-05-08 俄克拉荷马医学研究基金会 抗药性胶质瘤的治疗

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4928835A (en) * 1989-01-31 1990-05-29 Continental Pet Technologies, Inc. Injection molded preform, method of treating same and container formed therefrom
US5766909A (en) * 1992-02-04 1998-06-16 Merck & Co., Inc. DNA encoding inducible nitric oxide synthase
US5569902A (en) * 1995-01-17 1996-10-29 Welch Allyn, Inc. Contact two-dimensional bar code reader having pressure actuated switch
US5942385A (en) * 1996-03-21 1999-08-24 Sugen, Inc. Method for molecular diagnosis of tumor angiogenesis and metastasis
US6479481B1 (en) * 1999-06-04 2002-11-12 Ed. Geistlich Soehne Ag Fur Chemische Industrie Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS)
EP1267860A1 (en) * 2000-03-30 2003-01-02 Oklahoma Medical Research Foundation Butylnitrone containing compositions for inhibition of cancer development
EP1525003A1 (en) * 2002-06-28 2005-04-27 Pharmacia Corporation Methods and contrast agents useful in quantifying nitric oxide

Also Published As

Publication number Publication date
WO2007019065A3 (en) 2007-11-15
CA2617492A1 (en) 2007-02-15
AU2006278741A1 (en) 2007-02-15
WO2007019065A2 (en) 2007-02-15
EP1922075A2 (en) 2008-05-21
EP1922075A4 (en) 2009-10-14
US20070032453A1 (en) 2007-02-08

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