JP2009274981A - Drinking water having body heat-producing effect - Google Patents

Drinking water having body heat-producing effect Download PDF

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JP2009274981A
JP2009274981A JP2008127060A JP2008127060A JP2009274981A JP 2009274981 A JP2009274981 A JP 2009274981A JP 2008127060 A JP2008127060 A JP 2008127060A JP 2008127060 A JP2008127060 A JP 2008127060A JP 2009274981 A JP2009274981 A JP 2009274981A
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drinking water
water
hardness
heat production
body heat
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JP5770963B2 (en
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Shigemi Nagai
成美 永井
Yasuko Noda
泰子 野田
Keiichi Abe
圭一 阿部
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Suntory Holdings Ltd
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Abstract

<P>PROBLEM TO BE SOLVED: To provide drinking water which can promote the heat production of a living body in a daily seasonable intake to enhance the metabolic activity of the living body. <P>SOLUTION: Provided is the drinking water promoting the heat production of the living body in a daily reasonable intake by adjusting hardness to 60 to 2,000 and, optionally adjusting inner pressure of carbon dioxide to 1.0 to 3.8 kg/cm<SP>2</SP>at 20°C. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

本発明は、生体の熱産生促進効果を示す飲料水、およびその製造方法に関する。   The present invention relates to drinking water that exhibits an effect of promoting heat production of a living body, and a method for producing the same.

慢性的な運動不足や高カロリー食を原因とする太りすぎや肥満は、いまや全世界的な問題となっている。世界保健機構(WHO)によれば、2005年における世界の15歳以上人口のうち、太りすぎ(BMIが25以上)はおよそ16億人、肥満(BMIが30以上)はおよそ4億人と見積もられ、2015年には、太りすぎ人口が23億人、肥満人口が7億人を超えると予想されている。脂肪の過剰な蓄積に由来する太りすぎや肥満は、循環器系疾患や糖尿等のさまざまな疾患における大きなリスクファクターであり、その対策が急務である。   Overweight and obesity due to chronic lack of exercise and high-calorie diets are now a global problem. According to the World Health Organization (WHO), of the world's 15 years and older population in 2005, overweight (BMI is 25 or more) is estimated to be about 1.6 billion, obesity (BMI is 30 or more) is estimated to be about 400 million In 2015, overweight population is expected to exceed 2.3 billion and obese population is expected to exceed 700 million. Overweight and obesity resulting from excessive accumulation of fat are major risk factors in various diseases such as cardiovascular diseases and diabetes, and countermeasures are urgently needed.

人体の60〜70%は水で構成され、成人で1日約2.5リットルの水が体を出入りする。水自体のエネルギーはゼロであるが、Boschmannらは、飲水後に交感神経活動亢進とともに熱産生が生じる現象を、飲水誘発性熱産生(Water-induced thermogenesis; WIT)として報告し(非特許文献1)、水がマイナスカロリーとして抗肥満効果を有する可能性を示唆して注目を集めた。   60-70% of the human body is composed of water, and about 2.5 liters of water enters and exits the body in an adult day. Although the energy of water itself is zero, Boschmann et al. Reported a phenomenon in which heat production occurs with increased sympathetic nerve activity after drinking as water-induced thermogenesis (WIT) (Non-patent Document 1). Attracted attention, suggesting that water may have an anti-obesity effect as a negative calorie.

しかし、その後WITには否定的な報告が多く(例えばBrown et al.(非特許文献2))、現在も論争の最中にある。Brownらは、人において飲水が熱産生効果を有するか否かを検討する目的で実験を行い、室温にて蒸留水を飲むことはエネルギー消費を増加させないと結論づけている。   However, there have been many negative reports on WIT since then (for example, Brown et al. (Non-Patent Document 2)), and it is still in dispute. Brown et al. Conducted an experiment to examine whether drinking water has a heat production effect in humans, and concluded that drinking distilled water at room temperature does not increase energy consumption.

さらに、上記Boschmannらの報告では、一回の水の飲用量は500mlと大量であり、一度にこれだけの水を摂取することは難しい上に、用いた水の種類が記載されていないため、どのような種類の水が効果的にWITを促進するかについては何ら知られていない。
Boschmann M, Steiniger J, Hille U, Tank J, Adams F, Sharma AM, Klaus S, Luft FC, Jordan J. Water-induced thermogenesis. J Clin Endocrinol Metab88:6015-6019, 2003 Brown CM, Dulloo AG, Montani JP. Water-induced thermogenesis reconsidered: the effects of osmolality and water temperature on energy expenditure after drinking. J Clin Endocrinol Metab 91:3598-3602, 2006
In addition, the above Boschmann et al. Report that the amount of water consumed at one time is as large as 500 ml, and it is difficult to take this much water at one time, and the type of water used is not described. Nothing is known about how such types of water effectively promote WIT.
Boschmann M, Steiniger J, Hille U, Tank J, Adams F, Sharma AM, Klaus S, Luft FC, Jordan J. Water-induced thermogenesis.J Clin Endocrinol Metab88: 6015-6019, 2003 Brown CM, Dulloo AG, Montani JP.Water-induced thermogenesis reconsidered: the effects of osmolality and water temperature on energy expenditure after drinking.J Clin Endocrinol Metab 91: 3598-3602, 2006

本発明は、以上の背景から、無理のない実用的な摂取量で、効果的に生体の熱産生を促進し、代謝効率を高めることのできる飲料水を提供することを目的とする。
本発明者は、上記目的を達成すべく、実験条件を厳密にコントロールし、より精度の高い呼吸代謝サンプリングシステムを開発することにより、種々の硬度の水を用いてWIT測定実験を行った。その結果、1回の摂取量が250mlという無理なく摂取できる量の飲水によって、高い体熱産生効果が得られることがわかった。驚くべきことに、この効果は、炭酸水を用いた場合、顕著に高まることが明らかになり、本発明を完成するに至った。
In view of the above background, an object of the present invention is to provide drinking water that can effectively promote the heat production of a living body and increase the metabolic efficiency with a reasonable practical intake.
In order to achieve the above object, the present inventor conducted WIT measurement experiments using water of various hardnesses by strictly controlling the experimental conditions and developing a highly accurate respiratory metabolism sampling system. As a result, it was found that a high body heat production effect can be obtained by drinking water in an amount that can be reasonably ingested with a single intake of 250 ml. Surprisingly, this effect was found to increase significantly when carbonated water was used, leading to the completion of the present invention.

すなわち、本発明は、硬度が60〜2000の水を含む体熱産生促進効果を有する飲料水である。
また、本発明は、硬度が60〜2000であり、さらに炭酸ガスを摂氏20度における内圧として1.0〜3.8kg/cmで含む体熱産生促進効果を有する飲料水である。
That is, this invention is the drinking water which has the body heat production promotion effect containing the water whose hardness is 60-2000.
In addition, the present invention is a drinking water having a body heat production promoting effect having a hardness of 60 to 2000 and further containing carbon dioxide at 1.0 to 3.8 kg / cm 2 as an internal pressure at 20 degrees Celsius.

また、本発明は、硬度が60〜2000であり、さらに炭酸ガスを摂氏20度における内圧として1.0〜3.8kg/cmで含む飲料水の容器詰め飲料である。
さらに、本発明は、硬度を60〜2000に調整し、所望により摂氏20度における炭酸ガス内圧を1.0〜3.8kg/cmに調整し、さらに容器に詰める工程を含む体熱産生促進効果を有する容器詰めの飲料水の製造方法である。
Further, the present invention is a container-packed beverage having a hardness of 60 to 2000 and further containing carbon dioxide at an internal pressure of 20 to 20 degrees Celsius at 1.0 to 3.8 kg / cm 2 .
Further, the present invention adjusts the hardness to 60 to 2000, optionally adjusts the internal pressure of carbon dioxide gas at 20 degrees Celsius to 1.0 to 3.8 kg / cm 2 , and further promotes the production of body heat including filling the container. It is a manufacturing method of the potable drinking water which has an effect.

本発明は、硬度が60〜2000であり、所望により炭酸ガスを摂氏20度における内圧として1.0〜3.8kg/cmで含む体熱産生促進効果を有する飲料水、またはその製造方法である。
体熱産生促進効果を有する飲料水
本発明の飲料水は、硬度が60〜2000の範囲である。体熱産生効果は、水の硬度が高いほど大きくなる。従って、より大きい体熱産生効果を得るには硬度の高い飲料水が好ましく、例えば硬度90〜1500、より好ましくは硬度500〜1500、さらに好ましくは硬度1000〜1500である。
The present invention is a drinking water having a hardness of 60 to 2000, and optionally having carbon dioxide gas as an internal pressure at 20 degrees Celsius at an internal pressure of 1.0 to 3.8 kg / cm 2 and having a body heat production promoting effect, or a method for producing the same. is there.
Drinking water having an effect of promoting body heat production The drinking water of the present invention has a hardness in the range of 60-2000. The body heat production effect increases as the water hardness increases. Therefore, drinking water with high hardness is preferable in order to obtain a larger body heat production effect, for example, hardness 90-1500, more preferably 500-1500, and still more preferably 1000-1500.

硬度とは、水の中に含まれるミネラル類のうちカルシウムとマグネシウムの合計含有量の指標である。計算法によってアメリカ硬度、ドイツ硬度、フランス硬度、イギリス硬度等の種類があるが、本明細書および特許請求の範囲では、アメリカ硬度に基づいて標記している。アメリカ硬度とは、水1リットル中に含まれるカルシウムおよびマグネシウムの量を、炭酸カルシウムの量に換算する。計算式は、カルシウムの原子量は40、マグネシウムの原子量は24.3、炭酸カルシウムは100であるので、アルカリ硬度(mg/L)=カルシウム量(mg/L)×2.5+マグネシウム量(mg/L)×4.1となる。   Hardness is an index of the total content of calcium and magnesium among minerals contained in water. Depending on the calculation method, there are types such as American hardness, German hardness, French hardness, British hardness, etc., but in the present specification and claims, they are indicated based on the American hardness. With American hardness, the amount of calcium and magnesium contained in one liter of water is converted to the amount of calcium carbonate. The calculation formula is that the atomic weight of calcium is 40, the atomic weight of magnesium is 24.3, and calcium carbonate is 100. Therefore, alkali hardness (mg / L) = calcium amount (mg / L) × 2.5 + magnesium amount (mg / L) × 4.1.

本発明の飲料水は、より大きな体熱産生を得るには炭酸ガスを含んでいるのが好ましい。炭酸量は、ある温度における炭酸ガス内圧として表示することができる。本発明の飲料水は、炭酸ガスを摂氏20度における内圧として1.0〜3.8kg/cmで含む。好ましくは、摂氏20度における内圧として1.5〜3.5kg/cm、より好ましくは摂氏20度における内圧として2.0〜3.5kg/cmで含む。 The drinking water of the present invention preferably contains carbon dioxide gas in order to obtain greater body heat production. The amount of carbon dioxide can be displayed as the carbon dioxide internal pressure at a certain temperature. The drinking water of the present invention contains carbon dioxide at 1.0 to 3.8 kg / cm 2 as an internal pressure at 20 degrees Celsius. Preferably, 1.5~3.5kg / cm 2 as the internal pressure at 20 ° C, more preferably at 2.0~3.5kg / cm 2 as the internal pressure at 20 degrees Celsius.

本発明の体熱産生促進用飲料水に用いる原料水は、硬度が60〜2000に調整しうるものであれば、特に限定はされず、硬度が明らかな種々の天然水を用いても良いし、蒸留水やイオン交換水、または天然水に適宜ミネラルを添加して調整しても良い。添加するミネラルの種類および量は、硬度が60〜2000に制御されれば特に限定はされないが、好ましくは硬度が90以上になるように、カルシウムおよび/またはマグネシウムが添加される。   The raw water used in the drinking water for promoting body heat production according to the present invention is not particularly limited as long as the hardness can be adjusted to 60 to 2000, and various natural waters with obvious hardness may be used. Alternatively, minerals may be appropriately added to distilled water, ion exchange water, or natural water for adjustment. The type and amount of the mineral to be added is not particularly limited as long as the hardness is controlled to 60 to 2000, but preferably calcium and / or magnesium is added so that the hardness is 90 or more.

本発明の飲料水に炭酸ガスを含める方法については、摂氏20度におけるガス内圧が1.0〜3.8kg/cmに調整することができれば特に限定はされず、当業者が通常用いる方法を適宜適用して所望のガス内圧に調整しても良いし、天然の炭酸ガスを含んだ天然水を用いても良い。 The method of including carbon dioxide in the drinking water of the present invention is not particularly limited as long as the gas internal pressure at 20 degrees Celsius can be adjusted to 1.0 to 3.8 kg / cm 2. It may be applied as appropriate to adjust to a desired gas internal pressure, or natural water containing natural carbon dioxide gas may be used.

本発明の飲料水によって、効果的に体熱産生促進用効果を得るには、液温は0〜30度が適している。さらに好ましくは10〜25度である。
本発明の飲料水は、一回の飲水量では250ml以下にて、効果的に体熱産生促進効果をもたらすことができる。従って、本発明の飲料水は、50ml以上250ml以下の容量で容器詰めとされるのが好ましい。
In order to effectively obtain the effect of promoting body heat production with the drinking water of the present invention, the liquid temperature is suitably from 0 to 30 degrees. More preferably, it is 10 to 25 degrees.
The drinking water of the present invention can effectively bring about the effect of promoting body heat production when the amount of drinking water is 250 ml or less. Therefore, the drinking water of the present invention is preferably packed in a container having a capacity of 50 ml or more and 250 ml or less.

以上のようにして得られた飲料水は、体熱産生促進用飲料水としてそのまま用いることができ、実質的に0キロカロリーであり好ましい。また、本発明の効果に影響を及ぼさない範囲で、甘味料、酸味料、香料、酸化防止剤等を適宜加えて用いても良いし、果汁、乳、乳成分をさらに加えた飲料としても良い。また、ビタミン類、ポリフェノール類、アミノ酸、ペプチド、タンパク質等を添加した健康補助飲料としても良いし、適正な瓶に充填したドリンク剤とすることもできる。飲料水への添加物の添加法や、容器への充填法は、製品の性質等を考慮しつつ、当業者が適宜選択し、実施することができる。   The drinking water obtained as described above can be used as it is as drinking water for promoting the production of body heat, and is preferably 0 kilocalories. Moreover, as long as the effect of the present invention is not affected, sweeteners, acidulants, fragrances, antioxidants and the like may be added as appropriate, and fruit juice, milk, and beverages with further addition of milk components may be used. . Moreover, it is good also as a health supplement drink which added vitamins, polyphenols, an amino acid, a peptide, protein, etc., It can also be set as the drink agent with which the appropriate bottle was filled. A method for adding an additive to drinking water and a method for filling a container can be appropriately selected and carried out by those skilled in the art while considering the properties of the product.

本発明の飲料水は、体熱産生促進効果を有する。体熱産生促進効果は、例えば、酸素摂取量及び炭酸ガス排出量を測定し、Luskの表を用いてエネルギー消費量と呼吸商を求め、飲水誘発性熱産生(WIT)はコントロール(CT)試行のデータを基線として、台形公式にて各サンプル試行時のエネルギー消費量の積算値として求めることができる。
体熱産生促進効果を有する飲料水の製造方法
本発明の体熱産生促進効果を有する飲料水の製造方法は、飲料水の硬度を60〜2000に調整する工程、所望により摂氏20度における炭酸ガス内圧を1.0〜3.8kg/cmに調整する工程、さらに容器に詰める工程を含む。
The drinking water of the present invention has an effect of promoting body heat production. Body heat production promotion effect, for example, by measuring oxygen intake and carbon dioxide excretion, using the Lusk table to determine energy consumption and respiratory quotient, drinking water-induced heat production (WIT) is a control (CT) trial As a baseline, the trapezoidal formula can be used to calculate the integrated value of energy consumption during each sample trial.
Method for Producing Drinking Water Having Body Heat Production Promoting Effect The method for producing drinking water having the body heat production promoting effect of the present invention is a step of adjusting the hardness of drinking water to 60-2000, optionally carbon dioxide at 20 degrees Celsius. A step of adjusting the internal pressure to 1.0 to 3.8 kg / cm 2, and a step of filling the container.

硬度は、上述のように本明細書および特許請求の範囲では、アメリカ硬度に基づいて標記している。用いる原料水は、硬度が60〜2000に調整しうるものであれば、特に限定はされず、硬度が明らかな種々の天然水を用いても良いし、蒸留水やイオン交換水、または天然水に適宜ミネラルを添加して調整しても良い。添加するミネラルの種類および量は、硬度が60〜2000に制御されれば特に限定はされない。   As described above, the hardness is indicated based on the American hardness in the present specification and claims. The raw material water to be used is not particularly limited as long as the hardness can be adjusted to 60 to 2000, and various natural waters with obvious hardness may be used, or distilled water, ion exchange water, or natural water. You may adjust by adding a mineral suitably. The kind and amount of the mineral to be added are not particularly limited as long as the hardness is controlled to 60 to 2000.

摂氏20度におけるガス内圧の1.0〜3.8kg/cmへの調整は、当業者が通常用いる方法を適宜適用して、所望のガス内圧に調整することができる。
得られた飲料水の容器への充填は、製品の性質等を考慮しつつ、当業者が適宜選択し、実施することができる。
Adjustment of the gas internal pressure at 20 degrees Celsius to 1.0 to 3.8 kg / cm 2 can be adjusted to a desired gas internal pressure by appropriately applying a method usually used by those skilled in the art.
The filling of the obtained drinking water into the container can be appropriately selected and carried out by those skilled in the art while considering the properties of the product.

本発明を実施例によってさらに詳しく説明するが、本発明はこれらによって制限されるものではない。
〔実施例1〕 試験水を用いた飲水誘発性熱産生(WIT)の測定
(対象)
被験者は健康な若年女性とし、1)非肥満・非喫煙者で代謝性疾患を有していない、2)呼気ガス測定の経験者で測定データが安定している、の2条件を満たす10名を対象とした。
(試験サンプル)
試験サンプルとして、サンプルA(硬度94mg/L)、サンプルB(硬度94mg/L、炭酸入り)、サンプルC(硬度1468mg/L)の3種を用い、水の温度は15℃、量は250mlとした。各サンプルの組成を表1に示した。
The present invention will be described in more detail with reference to examples, but the present invention is not limited thereto.
[Example 1] Measurement of drinking water-induced heat production (WIT) using test water (subject)
The subjects were healthy young women, 10) who met the following conditions: 1) non-obese, non-smoker, no metabolic disease, 2) experienced expiratory gas measurement and stable measurement data Targeted.
(Test sample)
Three kinds of test samples, sample A (hardness 94 mg / L), sample B (hardness 94 mg / L, with carbonate), and sample C (hardness 1468 mg / L), were used. The water temperature was 15 ° C. and the amount was 250 ml. did. The composition of each sample is shown in Table 1.




























(試験方法)
何も飲まない日をコントロール(CT)試行とした。一人の被験者につき4試行をランダムな順序で、3週間以内の異なる日の同時刻に実施した。
(Test method)
The day when nothing was drunk was taken as a control (CT) trial. Four trials per subject were performed in random order at the same time on different days within 3 weeks.

各被験者には、検査日前日にはカフェイン、香辛料、かんきつ類、油の多い食事、激しい運動を避けること、および前夜10時からの絶食と実験開始2時間前からの絶飲を依頼した。4試行とも午前中の同時刻(8:30または9:30)に室温を25−26℃に調整した実験室に来室してもらい、トイレを済ませて検査衣に着替えた後、脚伸展座位にて、安静時、飲水負荷直後、および15、30、45、60分後の計6回、呼気ガスを8分ずつサンプリングした。
(呼吸代謝測定システム)
呼気ガス測定装置(ミナトエアロモニターAE-300S)より出力される換気量と酸素、二酸化炭素濃度の原信号をアンプで増幅(あるいはプログラム上で1Vあたりのサンプリング濃度を上限まで調節)し、さらに高性能のカード型A/D変換器を介して最大限の分解能でのサンプリングを行った(図1)。また、呼気をミキシングチューブに2呼吸分貯留させ、呼気のガス濃度が最も安定したチューブ末端にサンプリングセンサーを差し込み,測定ポイントとした。呼吸判定レベル値は1呼吸あたり100mLとし、測定中はオシロスコープで吸気と呼気の振幅が±5Vレンジに納まっていることを確認した。得られた酸素摂取量及び炭酸ガス排出量(15秒間の平均値)よりLuskの表を用いてエネルギー消費量と呼吸商を求めた。
Each subject was asked to caffeine, spices, citrus, oily meals, avoid intense exercise on the day before the test day, fasting from 10:00 the night before and drinking from 2 hours before the start of the experiment. At the same time in the morning (8:30 or 9:30) for all four trials, the room was adjusted to a room temperature of 25-26 ° C. Then, at a rest, immediately after drinking water, and after 15, 30, 45, and 60 minutes, the breath gas was sampled every 8 minutes for a total of 6 times.
(Respiratory metabolism measurement system)
Amplification (or adjust the sampling concentration per 1V to the upper limit in the program to the upper limit in the program) with the amplifier, the original signal of the ventilation volume and oxygen, carbon dioxide concentration output from the breath gas measuring device (Minato Aero Monitor AE-300S) Sampling with maximum resolution was performed via a high performance card-type A / D converter (FIG. 1). In addition, exhaled gas was stored in the mixing tube for 2 breaths, and a sampling sensor was inserted into the end of the tube where the gas concentration of exhaled gas was most stable, and used as a measurement point. The respiration judgment level value was 100 mL per respiration, and it was confirmed that the amplitude of inspiration and expiration was within the ± 5 V range with an oscilloscope during measurement. The energy consumption and respiratory quotient were obtained from the obtained oxygen intake and carbon dioxide emission (average value for 15 seconds) using the Lusk table.

飲水誘発性熱産生(WIT)は、コントロール(CT)試行のデータを基線として、台形公式にて各サンプル試行時のエネルギー消費量の積算値として求めた(図2)。つまり、飲水なしでは1時間安静にしている間にエネルギー消費量は経時的に低下するが、飲水試行後はエネルギー消費量レベルが維持、または若干の上昇が認められるため、CT試行との差分を、“飲水により産生されたエネルギー量”として算出した。   Drinking water-induced heat production (WIT) was determined as an integrated value of energy consumption during each sample trial using the trapezoidal formula with the control (CT) trial data as the baseline (FIG. 2). In other words, energy consumption decreases over time while drinking without water for 1 hour, but the level of energy consumption is maintained or slightly increased after drinking water. , And calculated as “amount of energy produced by drinking water”.

(結果)
表2に、各試行のエネルギー消費量の経時変化を示した。また、図3はエネルギー消費量を、測定前(REST)を100とした変化率で表し、同じく経時変化をみたものである。飲水なしのコントロール試行では、エネルギー消費量は経時的に低下し、60分後では約7%低下した。サンプルA試行ではエネルギー消費量の低下はなく、サンプルBとCではエネルギー消費量は経時的に上昇し、グループ間で有意な差異が認められた(p=0.015)。コントロールとの比較では、30分後にはサンプルC、45分後にはサンプルA、BおよびC、60分後にはサンプルAとCで有意な消費エネルギー量の上昇が認められた。
(result)
Table 2 shows the change over time in the energy consumption of each trial. FIG. 3 shows the energy consumption as a rate of change with the pre-measurement (REST) as 100, and also shows the change over time. In a control trial without drinking water, the energy consumption decreased with time and decreased by about 7% after 60 minutes. In the sample A trial, there was no decrease in energy consumption, and in samples B and C, the energy consumption increased with time, and a significant difference was observed between groups (p = 0.015). In comparison with the control, a significant increase in energy consumption was observed in sample C after 30 minutes, samples A, B and C after 45 minutes, and samples A and C after 60 minutes.

各試験サンプルの60分間のWITを、コントロールを基線として計算すると、サンプルではA3.6±1.5kcal、サンプルBでは4.8±1.9kcal、サンプルCでは5.5±1.4kcalであった。試行間での有意な差異が認められるとともに(ANOVA、p=0.038)、サンプルCではコントロール試行と比較して有意に高値を示した(p<0.05)(図4)。
発明の効果
本発明の飲料水は、硬度が60〜2000、さらに所望によりその摂氏20度における炭酸ガス内圧が1.0〜3.8kg/cmに制御されることにより、日常的に無理のない摂取量で生体熱産生を促進することができる。
The 60-minute WIT of each test sample was calculated using the control as the baseline, and it was A3.6 ± 1.5 kcal for the sample, 4.8 ± 1.9 kcal for the sample B, and 5.5 ± 1.4 kcal for the sample C. It was. Significant differences were observed between trials (ANOVA, p = 0.038), and Sample C showed significantly higher values compared to control trials (p <0.05) (FIG. 4).
Effect of the Invention The drinking water of the present invention has a hardness of 60 to 2000, and if desired, the internal pressure of carbon dioxide gas at 20 degrees Celsius is controlled to 1.0 to 3.8 kg / cm 2 , which is impossible on a daily basis. Biothermal heat production can be promoted with no intake.

図1は、呼吸代謝サンプリングシステムを示す。FIG. 1 shows a respiratory metabolic sampling system. 図2は、WIT(飲水誘発性熱産生)算出方法の例(サンプルBの場合)を示す。FIG. 2 shows an example of WIT (drinking water-induced heat production) calculation method (in the case of sample B). 図3は、各試験水の飲用時および非飲用時(CT)のエネルギー消費量(変化率)を示す。測定前(REST)を100としたときの変化率で表した(平均値±標準誤差)。グループ効果は二元配置分散分析(反復あり)で検定した。FIG. 3 shows energy consumption (rate of change) at the time of drinking each test water and when not drinking (CT). Expressed as the rate of change when the pre-measurement (REST) is 100 (average value ± standard error). Group effects were tested by two-way analysis of variance (with repetitions). 図4は、各試験水のWIT(単位、キロカロリー/時間)を示す。FIG. 4 shows the WIT (unit, kilocalories / hour) of each test water.

Claims (8)

硬度が60〜2000の水を含む、体熱産生促進効果を有する飲料水。 Drinking water having an effect of promoting body heat production, including water having a hardness of 60 to 2,000. さらに炭酸ガスを摂氏20度における内圧として1.0〜3.8kg/cmで含む、請求項1記載の飲料水。 Furthermore, the drinking water of Claim 1 which contains a carbon dioxide gas by 1.0-3.8kg / cm < 2 > as an internal pressure in 20 degreeC. 硬度が90〜1500である、請求項1または2記載の飲料水。 The drinking water of Claim 1 or 2 whose hardness is 90-1500. 摂氏20度における炭酸ガス内圧が1.5〜3.5kg/cm以下である、請求項2または3記載の飲料水。 The drinking water according to claim 2 or 3, wherein the internal pressure of carbon dioxide at 20 degrees Celsius is 1.5 to 3.5 kg / cm 2 or less. 摂氏0〜25度に保たれた、請求項1〜4のいずれか一項記載の飲料水。 The drinking water as described in any one of Claims 1-4 maintained at 0-25 degreeC. 請求項1〜5のいずれか一項記載の飲料水を含む容器詰め飲料。 The container stuffed drink containing the drinking water as described in any one of Claims 1-5. 50ml〜250mlの容量である、請求項6記載の容器詰め飲料。 The container-packed drink of Claim 6 which is a capacity | capacitance of 50 ml-250 ml. 体熱産生促進効果を有する容器詰めの飲料水の製造方法であって、
硬度を60〜2000に調整し、
所望により摂氏20度における炭酸ガス内圧を1.0〜3.8kg/cmに調整し、
さらに容器に詰める工程を含む、前記方法。
A method for producing container-packed drinking water having a body heat production promoting effect,
Adjust the hardness to 60-2000,
If necessary, adjust the carbon dioxide internal pressure at 20 degrees Celsius to 1.0-3.8 kg / cm 2 ,
The method further comprising the step of filling the container.
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WO2013002007A1 (en) * 2011-06-27 2013-01-03 サントリーホールディングス株式会社 Method for improving aftertaste of carbonated beverage
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