JP2009233081A - Panel and in vitro processing system - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a panel in a blood purifying system which is capable of controlling the temperature of a fluid efficiently and connects an inner tube path of the panel and a circular tube path outside the panel suitably. <P>SOLUTION: A panel 20 forms one part of a blood purifying fluid path and controls the temperature of a liquid of an in-vitro fluid path by contacting to a temperature control plate, and the panel 20 has a panel inner tube path A and a connecting tube path 130 for connecting the end of the panel inner tube path A and a circular tube path B of the outer in-vitro fluid path. One surface of the panel 20 is formed flatly and the fluid cross section of the panel inner tube path A is formed semicircularly to protrude to the other surface side of the panel 20, and the outer circumferential shape of the connecting tube path 130 is formed semicircularly to be adapted to the fluid path cross section of the end A1 of the panel inner tube path A, and the fluid path has a circular cross-section to be adapted to the outer circumferential shape of the circular tube path B, and one end of the connecting tube path 130 is inserted into the end A1 of a panel inner tube path A, and the other end of the connecting tube path A is configured to insert the circular tube path B. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a panel in which a part of an extracorporeal liquid flow path used for processing a bodily fluid taken out from the body of a patient or the like outside the body and returning it to the body, and an extracorporeal treatment system having the panel.

  In recent years, for example, a treatment method in which a body fluid such as blood is removed from the body and purified to return it to the body has become widespread. For example, in the treatment of diseases such as kidney disease and multi-organ failure that have serious circulatory system complications, blood purification methods, which are collectively referred to as continuous blood purification methods, have become widespread, especially in the field of emergency and intensive care. , Has been clinically effective.

  Specifically, the continuous blood purification method includes continuous hemofiltration (hereinafter referred to as “CHF”), continuous hemodialysis (hereinafter referred to as “CHD”), and continuous hemofiltration dialysis. There is a method (continuous hemofiltration, hereinafter referred to as “CHDF”), etc., which are used according to the purpose of treatment.

  CHF is a blood purifier that contains a semipermeable membrane, and drains waste fluid containing waste products from the blood through the filtration membrane, while supplementing the body with a replacement fluid continuously and slowly. It is a method to enforce. Further, CHD is a method of continuously and slowly performing correction of acid-base balance and the like by diffusion through a semipermeable membrane. The CHDF is a method in which the CHF and the CHD are combined so that a dialysis solution is flowed to the filtrate side in order to improve the small molecular weight removal capability of the CHF, and a dialysis effect is also obtained.

  In addition, as a blood purification method for liver failure, plasma exchange therapy (hereinafter referred to as “PE”), double filtration therapy (hereinafter referred to as “DFPP”), plasma adsorption therapy (plasma adsorption), (Hereinafter referred to as “PA”) and other apheresis therapies are used according to the purpose of treatment and have a clinical effect.

  PE is a method of removing harmful substances that are metabolized and detoxified by the liver and supplementing useful substances synthesized by the liver. Further, DFPP is a method that makes it possible to reduce the replenisher of the useful substance using a plasma separator and a plasma component separator. PA is a method in which separated plasma is perfused through an adsorption column to specifically and selectively remove a pathogenic substance.

  The above blood purification method is generally realized by a blood purification system. The blood purification system has a blood purification channel, and the blood purification channel includes a blood collection channel that sends blood collected from the patient to the blood purification unit, and a blood return channel that returns the blood of the blood purification unit to the patient. Depending on the application, the drainage flow path for draining blood from the blood purifier, the dialysate flow path for supplying dialysate to the blood purifier, the blood collection flow path or return It has a replacement fluid channel for supplying a replacement fluid to the blood channel (for example, see Patent Documents 1 and 2).

Japanese Patent Application Laid-Open No. 09-239024 JP 2007-268257 A

  By the way, it is necessary to adjust the temperature of the dialysis fluid, the replacement fluid, and the like passing through the blood purification flow path used in the blood purification method to a desired temperature in order to maintain a temperature balance with the body fluid when performing treatment. .

  As a method for adjusting the temperature of the liquid in the liquid channel, the inventor of the present invention forms a part 201 of the blood purification channel in the panel 200 as shown in FIG. I am thinking of doing something new in contact with. According to this method, for example, the liquid can be concentrated on the panel and the temperature can be adjusted collectively, so that the temperature can be adjusted efficiently. Moreover, since it is only necessary to attach the panel to the temperature control plate, the work of the medical staff during blood purification treatment is simplified.

  However, for example, as shown in FIG. 10, when a pipe 201 having a circular cross section is simply formed on the panel 200 and the panel 200 is to be brought into contact with the temperature control plate 202, the pipe 201 and the temperature control plate 202 are used. The contact area becomes smaller. In order to increase the contact area between the pipe 201 and the temperature control plate 202, it may be possible to form a recess corresponding to the shape of the pipe 201 in the temperature control plate 202. When attaching to the adjustment plate 202, it is necessary to fit the pipes 201 into the recesses by the number of the pipes 201, and the attachment work becomes complicated. In view of this, the inventor of the present invention considers flattening one surface of the panel 200 and projecting the pipe 201 to the other surface side of the panel 200 to form a channel cross-section in a semicircular shape.

  However, in that case, when an attempt is made to connect the circular tube 203 of the external pipe line of the panel 200 to the end of the semicircular pipe line 201 of the panel 200 as shown in FIG. It is conceivable that a gap is formed between the pipe 201 and the circular tube 203 and liquid leakage is likely to occur. It should be noted that an inexpensive circular tube is preferably used for the pipe line outside the panel 200.

  The present invention has been made in view of the above points, and can efficiently adjust the temperature, and can appropriately connect the internal pipe line of the panel and the circular pipe line outside the panel, and An object of the present invention is to provide an extracorporeal treatment system such as a blood purification system provided with the panel.

  In order to achieve the above object, the present invention provides a part of an extracorporeal liquid flow path used for processing a bodily fluid taken out of the body outside the body and returning it to the inside of the body. A panel for adjusting the temperature of the liquid in the liquid flow path, the panel being formed in the panel surface, the inner pipe line through which the liquid flows, the end of the inner pipe line and the outside of the panel A connection pipe line for connecting the circular pipe line of the extracorporeal liquid flow path, and one surface of the panel is formed flat, and the cross-section of the internal pipe line is the other of the panel. The connection pipe line is formed on the other surface side of the panel, and the flow path cross section is formed in a circular shape that matches the outer peripheral shape of the circular pipe line. And the said circular pipe line can be inserted in the said connection pipe line, It is characterized by the above-mentioned. The “connection pipe line” includes those manufactured integrally with the in-panel pipe line and those formed separately.

  According to the present invention, one surface of the panel is formed flat, and the cross-section of the channel in the panel is formed in a semicircular shape protruding to the other surface side of the panel. Is brought into surface contact with the temperature control plate, and the semicircular flat bottom surface of the pipe in the panel faces the temperature control plate side. As a result, heat exchange between the liquid passing through the panel and the temperature control plate is efficiently performed, and the temperature of the liquid is efficiently controlled. In addition, the connecting pipe is formed in a circular shape whose flow path cross section matches the outer circumference of the circular pipe, and the circular pipe can be inserted, so the gap between the pipe inside the panel and the circular pipe outside the panel can be inserted. Are connected in an airtight manner to prevent liquid leakage. Therefore, it is possible to appropriately connect the pipe line in the panel and the circular pipe line outside the panel while forming the pipe line in the panel in a semicircular shape to enable highly accurate temperature control. Furthermore, since the connecting pipe is provided on the other surface side of the panel, the connecting pipe does not protrude toward the temperature control plate even at the connecting portion between the inner pipe line and the outer circular pipe line. One surface of the panel can be closely attached by the temperature control plate. Therefore, the temperature of the liquid can be adjusted efficiently from this point.

  The connecting pipe is formed in a semicircular shape whose outer shape matches the flow path cross section of the end of the panel internal pipe, and one end of the connection pipe is inserted into the end of the panel internal pipe The circular pipe may be insertable into the other end of the connection pipe.

  The end of the in-panel pipe line and the connection pipe line may be welded at high frequency. Moreover, the inner diameter of the flow path cross section at the end of the inner pipe line may be larger than the inner diameter of the flow path cross section other than the end of the inner pipe line. Further, the connecting pipe line may have an inner diameter on the side of the in-panel pipe line smaller than that on the circular pipe line side. Moreover, a part of the pipe line in the panel may meander.

  A plurality of the in-panel conduits having at least two ends are formed, and the ends of the different in-panel conduits are connected to each other by a circular conduit outside the panel to form a same-system flow path. May be. A plurality of channels may be formed.

  The extracorporeal liquid channel is a blood purification channel for purifying blood collected from the body outside the body and returning it to the body, and the panel includes a channel for dialysate supplied for blood purification, and blood It may have at least a flow path for replacement fluid to be replenished.

  According to another aspect of the present invention, there is provided an extracorporeal treatment system for treating a bodily fluid taken out of the body outside the body and returning the bodily fluid to the inside of the body. The panel is attached to the extracorporeal treatment apparatus so that one flat surface is in surface contact with the temperature adjusting plate.

  According to the present invention, the temperature can be efficiently adjusted using the panel, and the connection between the internal pipe line of the panel and the circular pipe line outside the panel can be appropriately performed. The blood can be appropriately processed using the path.

  Hereinafter, preferred embodiments of the present invention will be described with reference to the drawings. FIG. 1 is an explanatory diagram showing an outline of a configuration of a blood purification system 1 as an extracorporeal treatment system in which a panel according to the present embodiment is used.

  In the present embodiment, for example, a blood purification system 1 that performs a continuous hemofiltration dialysis method (CHDF) in which a continuous blood filtration method (CHF) and a continuous hemodialysis method (CHD) are combined will be described.

  As shown in FIG. 1, the blood purification system 1 includes, for example, a blood purification flow path 2 as an extracorporeal liquid flow path and a blood purification apparatus 3 as an extracorporeal treatment apparatus. The blood purification channel 2 includes, for example, a blood purification unit 10 that purifies blood, a blood collection channel 11 that sends blood collected from a patient to the blood purification unit 10, and a return blood flow that returns blood from the blood purification unit 10 to the patient. A flow path 12, a drainage flow path 13 for flowing the drainage discharged from the blood purifier 10, a dialysate supply path 14 for supplying dialysate to the blood purifier 10, and a blood collection path 11 or a blood return path 12 has a replacement fluid supply flow path 15 for supplying a replacement fluid to the fluid.

  The blood purifier 10 has a filtration membrane 16 that removes waste and the like in the blood. The blood purifier 10, the blood collection channel 11 and the blood return channel 12 form a blood circulation circuit that collects blood from the patient and returns it. In this blood circulation circuit, the drainage flow path 13, the dialysate supply path 14, and the replacement fluid supply path 15 are formed to branch.

  The blood purification flow path 2 further includes a first panel 20 and a second panel 21 according to the present embodiment. In the first panel 20 and the second panel 21, a part of the drainage flow path 13, the dialysate supply flow path 14, and the replacement liquid supply flow path 15 are formed.

  For example, the drainage flow path 13 is connected to the blood purifier 10 at the upstream end. For example, the drainage pipe 50, the drainage panel inner pipe 51 in the first panel 20, the drainage pipe 52, The drain panel internal conduit 53, the drain conduit 54 in the first panel 20, the drain panel internal conduit 55, the drain conduit 56 in the second panel 21, and the drain in the first panel 20. A liquid panel inner line 57, a drain line 58, a transducer protection filter 59, a drain line 60, and an air pump 61 are provided in this order from the upstream side. A drainage storage section 62 that stores drainage is connected to the drainage panel inner line 55 of the second panel 21. An air valve 63 is connected to the drain line 60. Further, the drain panel inner conduit 53 is branched and connected to a drain conduit 64. The downstream end of the drainage pipe 64 is open.

  With this configuration, the drainage flow path 13 can store the drainage discharged from the blood purifier 10 in the drainage storage part 62 or drain it from the drainage line 64.

  The dialysate supply channel 14 includes, for example, a dialysate supply source 70, a dialysate conduit 71, a dialysate panel inner conduit 72 in the first panel 20, a dialysate conduit 73, and a dialysis in the second panel 21. Pipe line 74 in the liquid panel, dialysate pipe line 75, dialysate panel pipe line 76 in the first panel 20, dialysate pipe line 77, dialysate panel pipe line 78 in the first panel 20, and dialysis A liquid conduit 79 is provided in this order from the upstream side. The downstream end of the dialysate conduit 79 is connected to the blood purifier 10. A dialysate reservoir 80 that stores dialysate is connected to the dialysate panel inner pipe line 74 in the second panel 21. The dialysate reservoir 80 is also connected to the dialysate conduit 81, and a transducer protection filter 82 is connected to the other end of the dialysate conduit 81.

  With this configuration, the dialysate supply channel 14 can store, for example, the dialysate from the dialysate supply source 70 in the dialysate reservoir 80 and supply the dialysate to the blood purifier 10.

  The replacement fluid supply channel 15 includes, for example, a replacement fluid supply source 90, a replacement fluid conduit 91, a replacement fluid panel inner conduit 92 in the first panel 20, a replacement fluid conduit 93, and a replacement fluid panel inner conduit 94 in the first panel 20. The replacement fluid line 95, the connector 96, and the replacement fluid line 97 are provided in this order from the upstream side. The downstream end of the replacement fluid conduit 97 is connected to the blood return channel 12, for example. The liquid replacement panel inner line 92 of the first panel 20 is branched and connected to the liquid replacement line 98 and the liquid replacement panel inner line 99 in the second panel 21 in this order. A replacement fluid storage section 100 for storing a replacement fluid is connected to the replacement fluid panel inner pipe line 99. The replacement fluid reservoir 100 is also connected to the replacement fluid conduit 101, and a transducer protection filter 102 is connected to the other end of the replacement fluid conduit 101.

  With this configuration, the replacement fluid supply channel 15 can store, for example, the replacement fluid from the replacement fluid supply source 90 in the replacement fluid storage unit 100 and supply the replacement fluid to the blood return channel 12.

  The blood collection channel 11, the blood return channel 12, the drainage channel 13, the drainage channels 50, 52, 54, 56, 58, 60, 64, and the dialysate supply channel 14, the dialysate channels 71, 73. 75, 77, 79, 81, and the replacement fluid supply channels 91, 93, 95, 97, 98, and 101 of the replacement fluid supply channel 15, for example, are circular tubes made of thermoplastic and soft material. As a material of the circular tube, for example, soft vinyl chloride is used. The material of the circular tube is preferably a synthetic resin, particularly a thermoplastic resin, from the viewpoints of manufacturing cost, processability, and operability. Examples of thermoplastic resins include polyolefin resins, polyamide resins, polyester resins, polyurethane resins, fluorine resins, silicon resins, ABS (acrylonitrile-butadiene-styrene copolymer) resins, polyvinyl chloride, Polycarbonate, polystyrene, polyacrylate, polyacetal and the like can be exemplified, and any of them can be suitably used as a material for a circular tube. Among these, a soft material is preferable because it is resistant to bending and cracking and has excellent flexibility during operation, and soft vinyl chloride is particularly preferable for the reason of assembly.

  The blood purification apparatus 3 includes, for example, a tube pump 110 that pumps blood in the blood collection channel 11, a tube pump 111 that pumps drainage of the drainage channel 13 in the drainage channel 52, and dialysate in the dialysate channel 14. A tube pump 112 for pumping in the dialysate line 77, a tube pump 113 for pumping the drainage of the replacement fluid supply channel 15 in the replacement fluid line 93, a shutoff valve 114 for blocking the drainage channel 64 of the drainage channel 13, A shutoff valve 115 that shuts off the dialysate conduit 71 of the dialysate supply passage 14, a shutoff valve 116 that shuts off the replacement fluid conduit 91 of the replacement fluid supply passage 15, and the like.

  In addition, the blood purification device 3 includes a temperature adjustment plate 120 that adjusts the temperature of the liquid flowing in the first panel 20. The temperature adjustment plate 120 is erected vertically as shown in FIG. 2, and a support member 121 that supports the first panel 20 is provided on the upper and lower portions.

  Further, the blood purification apparatus 3 includes a weight scale (not shown) that measures the weight of the second panel 21. With this scale, it is possible to accurately grasp the water removal amount of the liquid discharged from the patient and the supply amount of the liquid supplied to the patient, and strictly manage the body fluid amount of the patient.

  Here, the configuration of the first panel 20 will be described. The first panel 20 has, for example, a substantially square shape as shown in FIG. 1, and is formed of a hard plastic such as hard vinyl chloride. The first panel 20 is preferably made of a material having biocompatibility or biological safety because the body fluid of the patient is directly or indirectly touched. The material is preferably a synthetic resin, particularly a thermoplastic resin, from the viewpoint of manufacturing cost, processability, and operability. Examples of thermoplastic resins include polyolefin resins, polyamide resins, polyester resins, polyurethane resins, fluorine resins, silicon resins, ABS (acrylonitrile-butadiene-styrene copolymer) resins, polyvinyl chloride, Polycarbonate, polystyrene, polyacrylate, polyacetal, and the like can be exemplified, and any of them can be suitably used as the material of the first panel 20. When the material of the first panel 20 is a hard plastic, the shape of the flow path does not deform even when the pressure of the liquid flowing in the flow path is under a negative pressure, and the contact with the temperature adjusting plate 120 described later is sufficiently achieved. For this reason, the temperature adjustment ability does not deteriorate. Further, since the flow path shape does not deform, the liquid flow rate does not change. For these reasons, in the present embodiment, for example, hard plastic is used as the material of the first panel 20.

  As described above, the first panel 20 has a plurality of in-panel conduits 51, 53, 57, 72, 76, 78, 92, 94 (hereinafter referred to as “in-panel conduit A”). Three systems of in-panel flow paths are formed: liquid, dialysate, and replacement fluid. Of the in-panel pipe line A, the dialysate panel inner pipe line 78 and the replacement fluid panel inner pipe line 94 are formed to meander in the first panel 20 surface, and are formed from the upper part to the lower part.

  As shown in FIGS. 2 and 3, the first panel 20 has one surface 20a formed flat and the other surface 20b formed with an in-panel pipe line A. The in-panel pipe line A is formed in a semicircular shape in which the cross section of the flow channel protrudes toward the other surface 20b. For example, as shown in FIG. 3, the first panel 20 is formed by bonding two plastic sheets. For example, a concave passage having a semicircular cross section is formed in the plastic sheet on the other surface 20b side, and the plastic sheet on the one surface 20a side is formed flat, and they are laminated to each other to connect the pipe line A in the panel. Is formed. The plastic sheets of the first panel 20 are bonded to each other by, for example, high frequency welding.

  As shown in FIG. 4, the end portion A <b> 1 of the in-panel pipe line A in the first panel 20 is formed at the outer edge portion of the first panel 20. In other words, the inner pipe line A and the outer pipe line of the first panel 20 are all connected at the outer edge of the first panel 20. As shown in FIG. 5, the end portion A <b> 1 of the in-panel pipe line A is formed in a semicircular shape having the same shape as the other portions and slightly larger in diameter than the other portions, and at the outer edge portion of the first panel 20. It is open. One end of the connecting pipe 130 is inserted into each end A1 of the in-panel pipe A.

  The material of the connecting pipe line 130 is preferably a synthetic resin, particularly a thermoplastic resin, from the viewpoint of manufacturing cost and processability. Examples of thermoplastic resins include polyolefin resins, polyamide resins, polyester resins, polyurethane resins, fluorine resins, silicon resins, ABS (acrylonitrile-butadiene-styrene copolymer) resins, polyvinyl chloride, Polycarbonate, polystyrene, polyacrylate, polyacetal and the like can be exemplified, and any of them can be suitably used as a material for the connecting pipe. Among them, the soft material is resistant to bending, cracking, and the like, and soft vinyl chloride is particularly preferable for the reason of assembly. The connection pipe line 130 is formed in a semicircular shape in which the outer peripheral surface 130 a matches the flow path cross section of the end portion A <b> 1 of the panel inner pipe line A. Further, the connection pipe line 130 has the above-mentioned circular drainage pipe lines 50, 52, 54, 56, 58, 64, dialysate pipe lines 71, 73, 75, 77, 79, and replacement fluid line 91. , 93, 95 (hereinafter referred to as “circular pipe path B”). Thereby, as shown in FIG. 6, the connection pipe line 130 is fitted into the in-panel pipe line A without a gap, and a circular flow path 130 b is formed at the center of the connection pipe line 130. A circular pipe B is inserted into the circular flow path 130 b at the other end of the connection pipe 130. Further, as shown in FIG. 7, the connection pipe line 130 is tapered on the inner peripheral surface, and the inner diameter on the panel inner pipe line A side is smaller than the circular pipe line B side.

  Note that the end A1 of the in-panel pipe line A and the connection pipe line 130 are bonded by, for example, high frequency welding. Further, the connection pipe line 130 and the circular pipe line B are bonded by, for example, solvent welding. Further, the inner pipe line A, the end A1 of the inner pipe line, and the outer peripheral surface 130a of the connecting pipe line 130 are formed in a semicircular shape as described above. Also included is a shape that combines a semicircle and a rectangle as shown in FIG.

  Next, the blood purification process performed using the first panel 20 and the blood purification system 1 will be described. First, a predetermined portion of the blood purification flow path 2 is attached to the blood purification apparatus 3. At this time, as shown in FIG. 2, the first panel 20 is supported by the support member 121 of the temperature adjustment plate 120, and the flat surface of one surface 20 a of the first panel 20 is in close contact with the temperature adjustment plate 120. Touched. Further, for example, the blood collection channel 11, the drainage channel 52, the dialysate channel 77, and the replacement fluid channel 93 are attached to the tube pumps 110 to 113, respectively.

  When the blood purification process for the patient is started, the collected blood is sent to the blood purification device 10, and the blood purified by the blood purification device 10 is returned to the patient. The dialysate is supplied to the blood purifier 10 through the dialysate supply channel 14. In the dialysate supply channel 14, for example, the dialysate in the dialysate reservoir 80 is adjusted to a predetermined temperature by the temperature adjustment plate 120 through the dialysate panel internal conduits 76 and 78 of the first panel 20, and thereafter Supplied to blood purifier 10. Further, the drainage generated in the blood purifier 10 is drained through the drainage flow path 13. Further, a replacement fluid is supplied to the blood return channel 12 through a replacement fluid supply channel 15. In the replacement fluid supply channel 15, for example, the replacement fluid in the replacement fluid storage unit 100 is adjusted to a predetermined temperature by the temperature adjustment plate 120 through the replacement fluid panel inner conduits 92 and 94 of the first panel 20, and then the blood return channel. 12 is supplied. The drainage, the dialysate supply, and the replacement fluid supply are performed while weighing the drainage storage unit 62, the dialysate storage unit 80, and the replacement fluid storage unit 100, for example, using a weighing scale.

  According to the above embodiment, the one surface 20a of the first panel 20 is formed flat, and the channel cross section of the in-panel pipe line A protrudes toward the other surface 20b of the first panel 20 half. Since it is formed in a circular shape, the one surface 20a of the first panel 20 is brought into surface contact with the temperature control plate 120, and the semicircular flat bottom surface of the inner pipe A in the panel faces the temperature control plate 120 side. Turn to. As a result, heat exchange between the liquid passing through the first panel 20 and the temperature adjustment plate 120 is efficiently performed, and the temperature of the liquid is efficiently adjusted. Further, the connection pipe line 130 is formed in a semicircular shape whose outer peripheral shape matches the flow path cross section of the in-panel pipe line A, and the flow path cross section is formed in a circular shape matching the outer peripheral shape of the circular pipe line B. One end of the connecting pipe 130 is inserted into the in-panel pipe A, and the circular pipe B can be inserted into the other end of the connecting pipe 120. For this reason, the connection between the in-panel pipe line A and the external circular pipe line B is made airtight, and liquid leakage can be prevented. Therefore, it is possible to appropriately connect the in-panel pipe line A and the circular pipe line B outside the panel while forming the in-panel pipe line A in a semicircular shape and enabling highly accurate temperature control. Further, since the connection pipe line 130 is provided on the other surface 20b side of the first panel 20 and is a semi-circular shape with a flat bottom surface on the temperature control plate 120 side, the connection between the in-panel pipe line A and the circular pipe line B is achieved. Even in the portion, the connecting pipe 130 does not protrude toward the temperature adjustment plate 120, and the one surface 20 a of the first panel 20 can be in close contact with the temperature adjustment plate 120. Therefore, the temperature of the liquid can be adjusted efficiently from this point.

  Since the inner diameter of the connecting line 130 on the side of the in-panel line A is smaller than that of the circular line B, the connecting line 130 is inserted while inserting the circular line B to an appropriate position in the connecting line 130. And the leakage of liquid between the circular pipe line B can be prevented.

  Since the dialysate panel inner pipe 78 and the replacement fluid panel inner pipe 94 which are a part of the panel inner pipe A are formed to meander, heat exchange with the temperature control plate 120 can be stably and efficiently performed. It can be carried out. Therefore, the temperature of the dialysate and the replacement fluid can be adjusted with higher accuracy.

  The first panel 20 is formed with a plurality of in-panel conduits A having at least two ends, and the different in-panel conduits A are connected to each other by a circular conduit B, so Therefore, the same liquid flows through the in-panel pipe line A a plurality of times. For this reason, heat exchange between the liquid and the temperature control plate 120 can be performed effectively. In the present embodiment, as described above, for example, the plurality of dialysate panel inner conduits 76 and 78 that are the panel inner conduit A are formed in the first panel 20, and these dialysate panel inner conduits are formed. The ends of 76 and 78 are connected to each other by a dialysate conduit 77 which is a circular conduit B, so that a dialysate supply channel 14 which is a channel in the panel of the same system is formed. In the present embodiment, for example, the ends of the drainage panel inner pipes 51 and 53 in the first panel 20 are connected to each other by the drainage pipe 52 to form the drainage flow path 13, and dialysis is performed. The end portions of the liquid panel inner conduits 76 and 78 are connected to each other by the dialysate conduit 77 to form the dialysate supply passage 14, and the end portions of the replacement fluid panel inner conduits 92 and 94 are connected to the replacement fluid conduit 93. Are connected to each other to form the replacement fluid supply flow path 15, and a plurality of three flow paths are formed in total.

  In addition, the dialysate panel internal pipe 78 and the replacement liquid panel internal pipe 94 of the panel internal pipe A are formed to meander in the first panel 20 surface, and are formed from the upper part to the lower part. Therefore, the temperature of dialysate and replacement fluid can be adjusted at once. As a result, the temperature of the dialysate and the replacement fluid can be adjusted to a uniform temperature suitable for the patient, so that the patient's blood purification treatment can be appropriately performed.

  The preferred embodiments of the present invention have been described above with reference to the accompanying drawings, but the present invention is not limited to such examples. It will be apparent to those skilled in the art that various changes and modifications can be made within the scope of the ideas described in the claims, and these are naturally within the technical scope of the present invention. It is understood that it belongs.

  For example, in the above embodiment, the connection line 130 of the first panel 20 is inserted into the in-panel line A. However, the connection line 130 is manufactured integrally with the in-panel line A. It may be. In the above embodiment, the first panel 20 is used for CHDF of the continuous blood purification method. However, the present invention is applicable to other blood purifications such as CHF, CHD, PE, DFPP, and PA. Applicable to law. In addition, the present invention can be applied to extracorporeal treatments such as blood transfusion other than blood purification, treatment with infusion, artificial cardiopulmonary treatment, and blood component donation.

  The present invention relates to an extracorporeal treatment system for treating a bodily fluid taken out of the body outside the body and returning it to the inside of the body, while efficiently adjusting the temperature of the liquid using the panel, and further, the internal conduit of the panel and the panel This is useful when properly connecting to external circular pipes.

It is the schematic which shows the structure of the blood purification system in this Embodiment. It is explanatory drawing which shows the attachment state to the temperature control board of a 1st panel. It is a fragmentary sectional view of the 1st panel. It is an enlarged view of the outer edge part vicinity of a 1st panel. It is explanatory drawing which shows the structure of the in-panel pipe line of a 1st panel, a connection pipe line, and a circular pipe line. It is a front view of the state which attached the connection pipe line to the edge part of the pipe line in a panel. It is a longitudinal cross-sectional view of the state which connected the pipe line in a panel, a connection pipe line, and a circular pipe line. It is explanatory drawing which shows the other aspect of semicircle shape. It is explanatory drawing which shows the panel before improvement. It is explanatory drawing of the longitudinal cross-section which shows the contact state of the panel which has the pipe line in a panel of a circular cross section, and a temperature control board.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Blood purification system 2 Blood purification flow path 3 Blood purification apparatus 20 1st panel 120 Temperature control board 130 Connection pipe line A Panel internal pipe line B Circular pipe line

Claims (10)

A part of the extracorporeal liquid channel used for processing the bodily fluid extracted from the body outside the body and returning it to the inside of the body is formed, and the temperature of the liquid in the extracorporeal liquid channel is adjusted by contacting the temperature adjusting plate Panel,
The panel is a connection pipe formed in the panel surface for connecting a liquid-in-panel conduit through which liquid flows, and an end portion of the panel-in-panel conduit and a circular conduit of an extracorporeal liquid passage outside the panel. Road, and
One side of the panel is formed flat,
The panel internal pipe line is formed in a semicircular shape in which the flow path cross section projects to the other surface side of the panel,
The connecting pipe is formed on the other surface side of the panel, and a cross section of the flow path is formed in a circular shape that matches the outer peripheral shape of the circular pipe, and the circular pipe is connected to the connecting pipe A panel characterized by being insertable.   The connecting pipe is formed in a semicircular shape whose outer shape matches the flow path cross section of the end of the panel internal pipe, and one end of the connection pipe is inserted into the end of the panel internal pipe The panel according to claim 1, wherein the circular pipe can be inserted into the other end of the connection pipe.   The panel according to claim 2, wherein an end of the inner pipe line and the connection pipe are welded at high frequency.   The inner diameter of the cross section of the flow path at the end of the inner pipe line is larger than the inner diameter of the cross section of the flow path other than the end of the inner pipe line. Panel described in.   The panel according to any one of claims 1 to 4, wherein the connection pipe line has a smaller inner diameter on the side of the inner pipe line than on the circular pipe line side.   The panel according to claim 1, wherein a part of the pipe line in the panel meanders. A plurality of in-panel conduits having at least two ends,
The ends of different in-panel pipe lines are connected to each other by a circular pipe line outside the panel to form a flow path of the same system. Panel.   The panel according to claim 7, wherein a plurality of channels are formed. The extracorporeal liquid channel is a blood purification channel for purifying blood collected from the inside of the body and returning it to the inside of the body,
The panel according to claim 8, comprising at least a flow path for dialysate supplied for blood purification and a flow path for replacement fluid to be replenished to blood. An extracorporeal treatment system for treating bodily fluids taken out of the body and returning them to the body,
An extracorporeal liquid flow path comprising the panel according to claim 1;
An extracorporeal treatment apparatus having a temperature control plate,
The extracorporeal treatment system, wherein the panel is attached to the extracorporeal treatment apparatus so that a flat surface is in surface contact with the temperature control plate.

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