JP2009022730A - Plaster - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a plaster allowing even the elderly whose fingertip force is weakened and movement is dulled to firmly grip a release sheet and easily peel the release sheet without slipping of fingers, having superior peeling workability and smoothly sticking it to the skin in the plaster used as a remedy for pains of the shoulders, elbows, knees and ankles. <P>SOLUTION: This plaster 1 is provided with a support body 2, an adhesive layer laminated on one face of the support body 2, and the release sheet 4 releasably stuck to the adhesive layer and formed with a cut line 7 extending from one edge part 5 to the other edge part 6 facing thereto, wherein the release sheet 4 has finger guide holes formed of scores 8 for placing parts of fingers in the left/right of the cut line 7. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a patch such as a plaster (plaster).

Conventionally, a patch such as a plaster (plaster) has been widely used as a therapy for pain in the shoulder, elbow, knee, ankle and the like. The patch is generally one in which an adhesive layer is laminated on one surface of a support and a release sheet is adhered to the adhesive layer. In use, the release sheet is peeled off and the adhesive layer is attached to the skin. For example, a patch comprising a support on which a paste is laminated, and a release sheet attached to the paste, wherein the release sheet is fixed by a linear, wavy, or sawtooth cut line. The thing provided with the strip | belt strip formed in the width | variety is known (patent document 1).
However, since the release sheet is in close contact with the adhesive layer, it is difficult to peel off, especially for elderly people because the fingertip strength is weak and the movement is slow, so the release work of the release sheet is difficult and the age increases. The frequency of use of the patch was increased, and the difficulty of peeling work of the release sheet was increased.
Therefore, development of a patch capable of easily peeling the release sheet from the adhesive layer is progressing even for elderly people.
As a conventional technique, for example, in (Patent Document 2), “a support having a paste layer laminated thereon and a first edge portion having a convex edge shape attached to the paste body and folded back at an end portion” is described. A patch "comprising one release sheet and a second release sheet attached to the plaster and partially overlapped on the first knob is disclosed.
Japanese Utility Model Publication No. 60-36563 JP 2007-68948 A

However, the above conventional techniques have the following problems.
(1) In the technique disclosed in (Patent Document 2), since the first picking portion and the second picking portion protrude, the first release sheet and the second release sheet are plastered by picking and pulling each with a finger. Can be peeled off. However, since both the first picking part and the second picking part are part of a thin release sheet having a thickness of 10 to 80 μm, the picking part is difficult to pick, and the surface of the release sheet on the side in contact with the plaster is subjected to a release treatment such as a silicon coating. Since it is easy to slip, the fingertip strength is weak especially in elderly people, and the fingertips tend to dry out. There was a problem that the knob could slip out, and the release sheet could not be easily peeled off.
(2) Speaking from the manufacturing aspect of the patch, the process of forming a first pick part by folding a part of the first release sheet and forming the second pick part on top of it is complicated and productive. It had the problem of being extremely lacking.
(3) Since the first knob and the second knob protrude without being attached to the plaster, the first knob or the second knob is used for packaging when the patch is stored in a packaging bag. Problems such as being caught on the edge of the bag, causing the release sheet to peel off before use or the release sheet to peel off and sticking the exposed plaster, etc., and causing the production line to stop or defective products to occur Had.
(4) Since the first picking part and the second picking part are not attached to the plaster and protrude, the first picking part and the second picking part are not attached to the packaging bag even when taken out from the packaging bag at the time of use. Since it was easily caught on the edge, it was difficult to take out, and there was a problem of lack of handleability.

  The present invention solves the above-mentioned conventional problems, and it is easy to peel off the release sheet by firmly gripping the release sheet so that the finger is hard to slip, and is excellent in release workability and can be applied smoothly to the skin. The purpose is to provide an agent. Furthermore, by including a transdermally absorbable drug in the adhesive layer, even elderly people with weak finger strength can peel off the release sheet themselves and apply them smoothly to the skin, while controlling a certain amount of active ingredients. It is an object of the present invention to provide a patch which can be continuously percutaneously absorbed and administered.

In order to solve the above conventional problems, the patch of the present invention has the following constitution.
The patch according to claim 1 of the present invention comprises a support, an adhesive layer laminated on one surface of the support, and the other of the adhesive layer that is detachably attached to the adhesive layer and that faces the other side. A release sheet in which a cut line extending to an edge is formed, and the release sheet has a finger hooking hole for hanging a part of a finger formed by a cut line on the left and right sides of the cut line have.
With this configuration, the following effects can be obtained.
(1) Since the release sheet is provided with finger hooking holes for hanging a part of the finger formed by the cut line on the left and right of the cut, when the part where the cut line is formed is pushed up from the support side with the finger, The surrounding release sheet is pushed up and peeled off from the adhesive layer, and a score line is opened to form a finger hook hole. If you put your finger between the release sheet that floated along the cut line and the adhesive layer, put your finger on the finger-holding hole, and sandwich the release sheet with another finger and put your finger on the finger-holding hole from the opposite side, Since they are put together through the finger-holding holes, the release sheet can be firmly picked up, and the finger is difficult to slip, so that the release sheet can be easily peeled off.
(2) The surface of the release sheet facing the adhesive layer has been subjected to a release treatment such as silicon coating, and it is very slippery due to the influence of the base component of the adhesive layer. Since the picked fingers can be brought into contact with each other, the release sheet can be firmly picked and peeled without slipping.
(3) When the portion where the cut line is formed is pushed up from the support side with a finger, the release sheet around the cut line is pushed up and peeled off from the adhesive layer, thereby opening the cut line and forming a finger hooking hole. When the cut line is formed in a substantially arc shape, a substantially U shape, a cross shape, etc., the push-up amount of the release sheet (tongue piece) around the cut line can be increased, so the tongue piece is raised and bent. As a result, the finger hooking hole can be greatly opened. For this reason, it is possible to easily peel off the release sheet by placing the finger firmly on the finger-holding hole and holding the release sheet.
(4) Since the periphery of the cut line adheres to the adhesive layer and does not protrude before use, it is only necessary to form a cut line and a cut line on the release sheet from the viewpoint of production. Materials can be used, and almost no new capital investment is required. Also, since there is no protruding part on the release sheet, it is not caught on the edge of the device or packaging bag, such as when transporting the production line or storing the patch in the packaging bag, and before use It is difficult to cause problems such as peeling or peeling sheet peeling and adhesion of an exposed adhesive layer, and there is no problem that the production line is stopped or defective products are generated. .
(5) Since the periphery of the score line is attached to the adhesive layer and does not protrude before use, it can be removed smoothly without being caught on the edge of the packaging bag during use. Excellent.

The release sheet is releasably attached to the entire surface of the adhesive layer, and is peeled off during use. By being detachably attached to the entire surface of the adhesive layer, before using the patch, the effect of preventing wrinkles from forming a highly flexible patch, It has the effect of preventing the escape of moisture. Further, when the patch is applied, the adhesive layer is brought into close contact with the affected area while peeling the release sheet, thereby giving a highly flexible patch with an effect of being applied neatly.
The constituent material of the release sheet is not particularly limited, and a film made of a synthetic resin such as polyester, polyvinyl chloride, polyvinylidene chloride, polyethylene terephthalate, a high-quality paper or a laminate film of glassine paper and polyolefin, a silicon processed paper, and the like are appropriately selected. The

The thickness of the release sheet is 300 μm or less, preferably 20 to 150 μm, more preferably 35 to 90 μm. This is because it imparts an appropriate rigidity, improves the handleability of the release work of the release sheet, and attaches the support to the affected skin area without any wrinkles.
As the thickness of the release sheet becomes thinner than 35 μm, the patch becomes weaker and it becomes difficult to peel off the release sheet, and it tends to cause wrinkles on the support when sticking, and as it becomes thicker than 90 μm, There is a tendency that the release sheet becomes harder and harder to stick. In particular, when the thickness is thinner than 20 μm or thicker than 300 μm, these tendencies become remarkable, so that neither is preferable.

The shape of the cut line that forms the finger-holding hole in the release sheet is not particularly limited as long as a part of the finger is applied when the release sheet is peeled off, and straight lines are formed on the left and right sides of the cut formed in the release sheet. Shape, wavy shape, sawtooth shape, substantially arc shape, semi-elliptical shape, cross shape, radial shape, T shape, Y shape, V shape, substantially H shape, substantially I shape, substantially U shape, mountain shape, etc. Things are used.
The cut line is formed near the cut line of the release sheet. This is because a finger is put on the finger-holding hole formed by the cut line and the release sheet is peeled off from the cut side.
In addition, 2-30 mm, Preferably 3-25 mm, More preferably, 5-20 mm is suitable as shortest distance (dimension A mentioned later) from the cut | interruption of a peeling sheet to the terminal of a notch line. Moreover, when converted into a ratio to the width of the patch (the length of the edge of the release sheet), the shortest distance (dimension A) from the cut line of the release sheet to the end of the cut line is 1/50 of the width of the patch. ˜1 / 5, preferably 3/100 to 3/20, more preferably 1/20 to 1/10. As this shortest distance becomes shorter, depending on the thickness of the release sheet, when the release sheet around the score line is started up or picked, a tear is formed in the release sheet from the end of the score line toward the cut line. It tends to occur and the edge portion of the release sheet tends to be cut. Particularly, when the ratio is less than 2 mm or the ratio is less than 1/50, this tendency becomes remarkable, which is not preferable. This is because, if the edge portion of the release sheet is cut and the cut line is connected to the cut line, it is difficult to detach the release sheet by placing a finger on the finger hooking hole. In addition, as the shortest distance becomes longer, the distance from the cut to the finger hole becomes longer, so that it tends to be difficult to put a finger on the finger hole, especially when it exceeds 30 mm or the ratio exceeds 1/5. Since this tendency becomes remarkable, it is not preferable.

The finger hook holes formed by the cut lines only need to be formed at least one each on the left and right sides of the cut. This is because when the release sheet is picked and peeled off, it is sufficient that the finger is hooked on the finger hooking hole. Moreover, it is preferable that a finger hooking hole is formed in the approximate center position of one edge part and the other edge part of a peeling sheet. This is because, when the release sheet is peeled off by placing a finger on the finger-holding hole, the support is difficult to twist and can be applied neatly without wrinkles.
When one finger hole is formed on each of the left and right sides of the cut, the shortest distance from one edge to the cut line where the cut of the release sheet is formed, the shortest distance from the other edge to the cut line (dimensions described later) As D), 10 mm or more, preferably 20 mm or more is suitable. Moreover, when converted into a ratio with the vertical length of the patch (distance between opposing edges of the release sheet), the shortest distance (dimension D) from the edge of the release sheet to the score line is the opposite of the release sheet. 1/7 or more, preferably 2/7 or more of the length between the edges to be applied is suitable. As this shortest distance is shortened, the finger hole formed by the score line becomes larger, and the area of the adhesive layer exposed from the finger hole becomes larger. It is done. In particular, when the ratio is less than 10 mm or the ratio is less than 1/7, this tendency becomes remarkable, which is not preferable.

A fold line extending from one edge to the other edge opposite to the cut line can also be formed on the release sheet on the outer side of the cut line (opposite the cut). As a result, when the release sheet is peeled off from the cut side by placing a finger on the finger-holding hole, the release sheet is prevented from being bent along the fold line due to the presence of the fold line and reattaching to the adhesive layer. If the patch is pressed against the affected part in this state, the adhesive layer maintains the exposed state, so that it can be attached to the affected part and preliminarily fixed. The release sheet can be peeled off from the adhesive layer by simply pulling the finger-holding hole of the release sheet with a finger, and the entire adhesive layer can be attached to the skin at the same time.
Here, a weakening line such as a perforation is used as the folding line. Since the weakening line is not intended to cut the release sheet, each cut forming the perforation does not need to penetrate the release sheet, and the release sheet may be thin. Furthermore, the weakening line need only be able to bend the release sheet easily, so it is not necessary to limit it to the perforation, and various forms such as a groove, a broken line, or a line that deteriorates the release sheet by heating are considered. It is done.

  As the cuts of the release sheet, those formed in various shapes such as a straight line, a wavy line, and a sawtooth are used. In particular, those formed in a wavy shape are suitable. Just fold the patch with a cut so that the support is on the inside, and the wavy line will protrude, and the release sheet will rise, so your finger will go under the edge of the release sheet and the adhesive layer, and the back side of the release sheet Hook your finger on the finger hole from the front, and pick the release sheet by placing your finger on the finger hole from the front side of the release sheet with another finger, and the release sheet can be easily peeled off. Because.

It is preferable that the release sheet is colored on the edge of the score line or the edge of the cut, is marked with an arrow or a symbol, or has a description of how to make a finger hook. This is because it can be used as a reference for the target of the push-up position and the usage method when pushing up with a finger from the support side, and a series of peeling operations can be performed smoothly even for an elderly person or the like who has reduced visual acuity.
Moreover, it is preferable that the finger hole is formed substantially symmetrically with respect to the cut line. When applying the patch to the affected skin area while putting the release sheet on the finger skin hole and pulling the release sheet along the surface of the affected skin area, This is because it can be applied without wrinkles or air entering the patch.

The constituent material of the support is not particularly limited, but polyethylene terephthalate (PET), ethylene-vinyl acetate copolymer (EVA), polyvinylidene chloride, polyethylene, polyester, polyvinyl acetate, polybutadiene, styrene-butadiene or styrene- Block copolymer resin mainly composed of isoprene, nylon, polyurethane, alkoxyalkyl (meth) acrylate copolymer, film made of synthetic resin such as polyvinyl acetal, polyamide, rayon, woven fabric, knitted fabric, non-woven fabric, or laminate thereof The body is preferably used.
The support preferably has moderate flexibility and stretchability. Furthermore, the thickness of the support is preferably 0.01 mm to 5 mm. When the thickness of the support is less than 0.01 mm, handling tends to be poor and wrinkles tend to occur. This is because it tends to be easily done.

  A pressure-sensitive adhesive is used as the main component of the pressure-sensitive adhesive layer laminated on one surface of the support. The constituent material is not particularly limited, but a material having an adhesive force capable of fixing the drug to the skin surface at room temperature for a long time is preferable. Examples thereof include an acrylic adhesive, a rubber adhesive, a silicon adhesive, and the like. . Among these, rubber-based pressure-sensitive adhesives are preferably used from the viewpoint of good adhesive properties and drug release properties. Particularly, 2-ethylhexyl (meth) acrylate, butyl (meth) acrylate, natural rubber, synthetic isoprene rubber, polyisobutylene, Polyvinyl ether, polyurethane, polyisoprene, polybutadiene, styrene-butadiene copolymer, styrene-isoprene copolymer, styrene-isoprene-styrene block (SIS) copolymer and the like are more preferably used. Furthermore, when using an SIS copolymer, SIS base (trade name: Califlex TR-1107, Califlex TR-1111, Califlex TR-1112, Califlex TR-1117) manufactured by Shell Chemical Co., Ltd., Clayton SIS base (trade name: D-KX401CS), SIS base manufactured by Nippon Synthetic Rubber Co., Ltd. (trade names: JSR5000, JSR5002, JSR5100, JSR5200), SIS base manufactured by Nippon Zeon Co., Ltd. , Quintac 3421) and the like are most preferably used.

  You may add compounding agents, such as a tackifier, a softener, a filler, an antioxidant, a solubilizer, an absorption promoter, to the adhesion layer as needed. As such a compounding agent, for example, an alicyclic saturated hydrocarbon resin (manufactured by Arakawa Chemical Industry Co., Ltd., trade name: Alcon P-100, etc.), rosin ester (manufactured by Arakawa Chemical Industries Ltd., trade name: KE-311), KE-100, etc.), hydrogenated rosin ester (made by Hercules, trade names: Foral 105, Foral 85, etc.), hydrogenated alicyclic hydrocarbons (made by Exxon Chemical, trade name: Escollets 5300, etc.), polyterpene resin , Petroleum resin, phenol resin tackifiers; liquid paraffin, polybutene, liquid polyisobutylene, softeners such as animal and vegetable oils; fillers such as zinc oxide and titanium oxide; antioxidants such as butylhydroxytoluene; crotamiton, polyethylene glycol (Including various macrogol), 1,3-butylene glycol, solubilizers such as propylene glycol, etc. And the like. If necessary, an absorption enhancer may be contained in the pressure-sensitive adhesive to improve the skin permeability of the drug. Examples of such absorption enhancers include isopropyl myristate and diethyl sebacate. , Propylene carbonate, sorbitan oleate, crotamiton, L-menthol, mint oil, N-methyl-2-pyrrolidone, dl-camphor, sorbitan monolaurate, sodium oleyl phosphate, sodium lauryl sulfate, octylphenyl ether, lauryl ether, sorbitan Examples include monolaurate, lauroyl diethanolamide, lauroyl sarcosine, oleoyl sarcosine sugar ester, and the like. In addition, various additives usually used in formulating patches such as pigments, fragrances, refreshing agents, UV absorbers, surfactants, stabilizers, fillers, antioxidants, pH adjusters, etc. Depending on the purpose of the agent, one or more kinds may be appropriately blended in the pressure-sensitive adhesive.

A drug can be blended in the adhesive layer. The drug to be incorporated is not particularly limited as long as it is a transdermally absorbable drug, and may be any systemic or local transdermal drug. For example, systemic drugs include anti-inflammatory agents (steroidal or non-steroidal anti-inflammatory agents, narcotic analgesics, hypnotic sedatives, steroids, tranquilizers, antihypertensives, antihypertensive diuretics, antibiotics, systemic Anesthetics, antibacterial agents, antifungal agents, coronary vasodilators, antihistamines, analgesics, sex hormone agents, antidepressants, cerebral circulation improving agents, antitumor agents, local anesthetics, bactericidal disinfectants, corticosteroids , A smoking cessation aid, a dementia treatment agent, etc. As a compounding quantity, it prescribes | regulates suitably within the range of 0.001-20 mass%.
More specific examples include steroidal anti-inflammatory agents such as cortisone, hydrocortisone, prednisolone, methylprednozone, triamcinolone, dexamethasone, betamethasone, parameterzone; methyl salicylate, glycol salicylate, indomethacin, diclofenac, flurbiprofen, Non-steroidal anti-inflammatory drugs such as ketoprofen, felbinac and loxoprofen; narcotic analgesics such as fentanyl and buprenorphine; angina drugs such as nitroglycerin and isosorbide; bronchodilators such as tulobuterol; post-percutaneous herpes zoster such as lidocaine Pain treatment; Smoking cessation aids such as nicotine; Anti-Parkinson agents such as bergolide; Urinary incontinence / frequent urine treatments such as oxybutynin; Antihypertensive agents such as clonidine; Donepezil hydrochloride (trade name Ali) Script), rivastigmine (trade name Exelon), Isupuronikurin, memantine hydrochloride, galantamine hydrobromide, dementia therapeutic agent such as lecozotan hydrochloride, are preferred. The drugs listed here are pharmaceutically acceptable, such as inorganic salts (hydrochloric acid, sulfate, nitrate, sodium, potassium, calcium, etc.) or organic salts (citric acid, fumaric acid, tartaric acid, mesylic acid, acetic acid, etc.) Also included are drugs that can form additional addition salts.
Among these drugs, non-steroidal anti-inflammatory agents such as methyl salicylate, glycol salicylate, indomethacin, diclofenac or a salt thereof, flurbiprofen, ketoprofen, felbinac, loxoprofen or a salt thereof are particularly preferable. As a compounding quantity, 0.1-20 mass%, Preferably it is desirable to mix 0.3-10 mass%.
Also, mint oil, menthol or menthol-related compounds may be blended as a medicinal aid or a cooling agent. Alternatively, a warming stimulant such as pepper, capsicum extract, capsaicin, nonanoic acid vanillylamide, nicotinic acid benzyl ester may be blended.

  The thickness (coating thickness) of the adhesive layer is preferably 10 to 400 μm. If the thickness of the pressure-sensitive adhesive layer exceeds 400 μm, the release of the drug contained in the pressure-sensitive adhesive tends to be poor, whereas if it is less than 10 μm, the adhesiveness to the skin tends to be inferior and tends to cause peeling. is there.

  The patch preferably has its corners cut into arcs. Once a part of the patch is turned over and peeled off, the stratum corneum and dust adhere to the part and it is difficult to apply it again. In particular, when the shape of the patch is rectangular, the corners are caught by clothes and the like, and tend to be turned off first and easily peeled off. Therefore, it is preferable to make the corners of the patch arc-shaped so that it is not easily caught by clothes, etc., and this tends to prevent the occurrence of peeling more sufficiently. Furthermore, when making the corner into an arc shape in the patch, the arc preferably has a curvature radius of 5 mm or more. This is because when the radius is less than 5 mm, reduction of peeling at the time of sticking tends not to be sufficiently achieved.

  The patch of the present invention can be applied to tapes, dressings, cooling sheets, cosmetic sheets, etc., as well as external preparations applied to the skin such as plasters (plasters).

The patch according to claim 2 of the present invention includes a support, an adhesive layer laminated on one surface of the support, a release sheet releasably attached to the adhesive layer, and one of the release sheets. A first cut extending from the edge to the other edge facing the second cut, and a second cut extending from the one edge of the release sheet to the other edge facing the first cut. The release sheet has a configuration including finger hooking holes for hanging a part of a finger formed by a cut line on the left side of the first cut and the right side of the second cut. ing.
With this configuration, in addition to the operation obtained in the first aspect, the following operation can be obtained.
(1) First, the release sheet between the first cut and the second cut is peeled to expose the adhesive layer, and this adhesive layer is affixed to the affected area to be preliminarily fixed. The remaining release sheet can be picked and peeled off, and the entire surface of the adhesive layer can be attached to the affected area. In this way, the release sheet has a first cut and a second cut formed at intervals, and a part of the adhesive layer can be attached to the affected area and preliminarily fixed. If the site is bad, it can be re-applied at the preliminary fixing stage, and can be reliably applied to the desired site of the affected area.
(2) Since a part of the adhesive layer can be affixed and fixed to the affected area before the entire surface of the adhesive layer is affixed, it is difficult to slip when the remaining release sheet is peeled off, and it can be easily affixed neatly with one hand.

  Here, since it is the same as that of what was demonstrated in Claim 1 about a support body, an adhesion layer, a peeling sheet, a score line, and a finger hook hole, description is abbreviate | omitted. Further, the first cut and the second cut are the same as the cuts described in claim 1, and thus the description thereof is omitted.

It is preferable that the first cut and the second cut are formed with substantially equal intervals over the entire length of the first cut and the second cut. The intervals are substantially equal over the entire length when the first cut and the second cut are formed in a wavy line shape or a sawtooth shape, etc., and the distance between the center lines that bisect the amplitude of the wavy line or the sawtooth shape. Is equal over the entire length. Thereby, when peeling a peeling sheet, since a support body cannot twist easily, a support body can be affixed neatly to an affected part without a wrinkle.
As the interval between the first cut and the second cut, 10 to 30 mm is preferably used as the shortest distance. As a result, the release sheet sandwiched between the first cut and the second cut can be peeled off and applied to the affected area to ensure the adhesive force when preliminarily fixed, and the support can be applied cleanly without wrinkles. It can also be re-applied during preliminary fixing.

Invention of Claim 3 of this invention is the patch of Claim 1 or 2, Comprising: The said cut line is formed at intervals with the said cut, the said 1st cut, and the said 2nd cut. A main cut portion, and a cut-side extending portion extending from the main cut portion in the direction of the cut, the first cut, and the second cut.
With this configuration, in addition to the operation obtained in the first or second aspect, the following operation can be obtained.
(1) Since the incision line has a main incision part and a cut-side extension part, the cut line is pushed up from the support side, and the tongue of the incision line formed by the main incision part and the cut-side extension part is A large finger-hanging hole can be formed by starting up a large amount and opening a large cut line. For this reason, it is possible to easily peel off the release sheet by placing the finger firmly on the finger-holding hole and holding the release sheet.
(2) When the tongue of the raised score line is folded back toward the cut line side of the release sheet, the thickness of the release sheet floating along the cut and the folded tongue piece can be increased to increase the thickness. If you pick up the overlapping part of the tongue that is folded with your finger on the finger, it will be difficult for the elderly with weak fingertips to slip out of the finger, so the release sheet can be easily peeled off. .
(3) If the tongue of the cut line that has been raised is bent, it can be easily picked up even when the release sheet is placed on a table or dropped on the floor. Because the release sheet is thin and smooth, it is difficult to pick it up in close contact with the surface of the table etc., but when the release sheet is on the table etc. with the folded tongue down, the release sheet and the table Since the release sheet does not adhere to the table etc., it is easy to pick it up.If the release sheet is on the table etc. with the folded tongue up, pick the folded tongue This is because it can be picked up.

Here, as the main cut portion, one formed in a straight line shape, a wavy line shape, a sawtooth shape, a substantially mountain shape, or the like is used.
As the cut side extending portion, either one extending from the end of the main cut portion or one extending in a branched shape from the line of the main cut portion can be used. The overall shape of the cut line is substantially circular. An arc shape, a semi-elliptical shape, a cross shape, a radial shape, a T shape, a substantially H shape, a substantially I shape, a substantially U shape, a mountain shape, or the like is used.

The width (longitudinal width) of the cut line having the main cut portion and cut side extending portion in the direction orthogonal to the edge of the release sheet on which the cut is formed is 5 to 30 mm, preferably Is preferably 7 to 25 mm, more preferably 10 to 20 mm. When converted into a ratio with the vertical length of the patch (distance between opposing edges of the release sheet), the width of the score line (vertical width) (dimension C) is the distance between the opposing edges of the release sheet. 1/14 to 6/7, preferably 1/10 to 5/14, more preferably 1/7 to 3/7.
Further, the width (lateral width) of the cut line in the direction parallel to the edge portion of the release sheet (dimension B described later) is 5 to 50 mm, preferably 10 to 35 mm, more preferably 12 to 25 mm. It is. When converted into a ratio to the width of the patch (the length of the edge of the release sheet), the width of the cut line (width in the lateral direction) (dimension B) is 1/20 to 3/10 of the width of the patch, 1/10 to 1/4 is preferable, and 3/25 to 1/5 is more preferable.
As the longitudinal width (dimension C) of the score line becomes shorter than 10 mm or the ratio becomes smaller than 1/7, it tends to be difficult to put a finger on the finger hole and peel off the release sheet, from 20 mm. As the length becomes longer or the ratio becomes larger than 3/7, the area of the adhesive layer exposed from the finger hooking hole becomes larger, and therefore, the adhesive layers tend to stick to each other and tend to become tangled. In particular, when the ratio is less than 5 mm or the ratio is less than 1/14, the ratio exceeds 30 mm or the ratio exceeds 6/7, these tendencies become remarkable, which is not preferable.
In addition, as the lateral width of the score line (dimension B) becomes shorter than 12 mm or the ratio becomes smaller than 3/25, there is a tendency that it is difficult to put a finger on the finger hooking hole and it is difficult to peel off the release sheet. As the area becomes longer than 25 mm or the ratio becomes larger than 1/5, the area of the adhesive layer exposed from the finger hooking hole becomes larger, and thus the adhesive layer tends to adhere to each other and stick to the support when sticking. . In particular, if it is less than 5 mm or the ratio is less than 1/20, it exceeds 50 mm or the ratio exceeds 3/10, these tendencies become remarkable, which is not preferable.

Invention of Claim 4 of this invention is a patch of Claim 3, Comprising: The said cut line is on the other side of the said cut, the said 1st cut, and the said 2nd cut from the said main cut part. It has the structure provided with the extended outside extension part.
With this configuration, in addition to the operation obtained in the third aspect, the following operation can be obtained.
(1) Since the outer extending portion is provided to extend to the main cut portion, the cut line is wide open and the finger hook hole is opened widely. And can be easily peeled off.

  Here, as the outer extending portion, any of those extended from the end of the main cut portion and those extended in a branched shape from the line of the main cut portion can be used. What is formed in a cross shape, radial shape, T shape, Y shape, substantially H shape, substantially I shape or the like is used.

The invention according to claim 5 of the present invention is the patch according to claim 3 or 4, wherein the cut line extends from the end of the cut-side extending portion to the cut, the first cut, and the first cut. It has the structure provided with the parallel notch part extended in the substantially parallel direction with the 2nd cut.
With this configuration, in addition to the operation obtained in the third or fourth aspect, the following operation can be obtained.
(1) Since it has a parallel cut portion extending in a direction substantially parallel to the cut and the like from the end of the cut side extending portion, the cut is made when the tongue piece formed by the cut line is raised or picked It can prevent that a tear arises in a peeling sheet toward a cut from a side extension part, and can prevent that a peeling sheet tears and a cut line will be connected with a cut. This is because, if the cut line is connected to the cut line, it is difficult to remove the release sheet by placing a finger on the finger hooking hole.

Invention of Claim 6 of this invention is a patch in any one of Claim 3 thru | or 5, Comprising: The said peeling sheet is extended in the said cut | interruption side extension part or the said parallel cut part. It has the structure provided with the made folding line.
With this configuration, in addition to the action obtained in any one of claims 3 to 5, the following action is obtained.
(1) Since it is provided with a fold line extending to the cut-side extension part or the parallel cut part, the tongue piece of the raised cut line can be easily folded or folded by the fold line. Is prevented from reattaching to the adhesive layer. For this reason, a series of peeling operations can be performed smoothly, and the handleability is remarkably excellent.

  Here, a weakening line such as a perforation is used as the folding line. Since the weakening line is not intended to cut the release sheet, each cut forming the perforation does not need to penetrate the release sheet, and the release sheet may be thin. Furthermore, the weakening line need only be able to bend the release sheet easily, so it is not necessary to limit it to the perforation, and various forms such as a groove, a broken line, or a line that deteriorates the release sheet by heating are considered. It is done.

Invention of Claim 7 of this invention is a patch in any one of Claim 1 thru | or 6, Comprising: The said adhesion layer has the structure containing the transdermally absorbable drug. .
With this configuration, in addition to the action obtained in any one of claims 1 to 6, the following action is obtained.
(1) By containing a transdermally absorbable drug in the adhesive layer, a constant dose of the active ingredient can be absorbed through the skin while performing continuous and controlled control. Moreover, the drug concentration in the blood is maintained for a long period of time, and side effects can be reduced without burdening the digestive tract such as the stomach and intestines and the liver as in the case of oral preparations.
(2) It can be administered to elderly people and children, and a safe and effective therapeutic effect can be expected.
(3) By using the patch, the use status of the drug can be confirmed at a glance, so that a caregiver can expect merit such as easy understanding of the compliance status.

  Since the specific content of the transdermally absorbable drug has been described in claim 1, the description thereof is omitted here.

The invention according to claim 8 of the present invention is the patch according to claim 7, wherein the transdermally absorbable drug is an anti-inflammatory agent.
With this configuration, in addition to the operation obtained in the seventh aspect, the following operation can be obtained.
(1) Since the medicinal components of anti-inflammatory agents are absorbed through the skin through the skin and directly act on the inflamed muscles and joints, stiff shoulders, low back pain, joint pain, muscle pain, bruises, sprains, tendonitis, elbow Expected to be effective in pain.

  As the anti-inflammatory agent, either a steroidal anti-inflammatory agent or a non-steroidal anti-inflammatory agent can be used. Since the specific contents of these anti-inflammatory agents have been described in claim 1, their description is omitted here.

The invention according to claim 9 of the present invention is the patch according to claim 7, wherein the transdermally absorbable drug is a therapeutic agent for dementia.
With this configuration, in addition to the operation obtained in the seventh aspect, the following operation can be obtained.
(1) The therapeutic agent for dementia, which is a medicinal component, can be safely and effectively passed through the skin by using the therapeutic agent for dementia that has been conventionally used as an oral preparation for transdermal absorption. Can be migrated to. In addition, the therapeutic effect can be maintained for a long time.

  Since the specific content of the dementia therapeutic agent has been described in claim 1, the description thereof is omitted here.

As described above, according to the patch of the present invention, the following advantageous effects can be obtained.
According to the invention of claim 1,
(1) Since the release sheet is provided with a finger hook hole for hanging a part of a finger formed by a cut line on the left and right sides of the cut, the finger is inserted between the release sheet raised along the cut and the adhesive layer. If you put your finger on the finger hole and hold the finger on the finger hole from the opposite side with another finger sandwiching the release sheet, the fingers will contact each other through the finger hole, so you can grip the release sheet firmly and your finger will slide Since it becomes difficult, the release sheet can be easily peeled off, and a patch excellent in release workability can be provided.
(2) The surface of the release sheet facing the adhesive layer has been subjected to a release treatment such as silicon coating, and is very slippery due to the influence of the base component of the adhesive layer. Since the picked fingers can be brought into contact with each other, the release sheet can be firmly picked and peeled without slipping, and a patch excellent in release workability can be provided.
(3) When the cut line is formed in a substantially arc shape, a substantially U shape, a cross shape, etc., the amount of push-up of the tongue piece made of the cut line can be increased, so the tongue piece can be raised and bent. It is possible to provide a patch excellent in peeling workability that can be formed by opening a large cut line to form a large finger-holding hole and holding the release sheet firmly by placing the finger firmly on the finger-holding hole.
(4) Since the tongue of the cut line adheres to the adhesive layer and does not protrude before use, it is only necessary to form a cut line and a cut line on the release sheet from the viewpoint of production. It is possible to provide a patch that can utilize materials and materials and requires almost no new capital investment. Also, since there is no protruding part on the release sheet, it is not caught on the edge of the device or packaging bag, such as when transporting the production line or storing the patch in the packaging bag. It is difficult to cause problems such as peeling or peeling of the release sheet and sticking the exposed adhesive layer, and there is no problem that the production line stops or defective products are generated, and it is extremely excellent in productivity. A patch can be provided.
(5) Since the tongue of the cut line adheres to the adhesive layer and does not protrude before use, it can be removed smoothly without being caught on the edge of the packaging bag when taken out from the packaging bag. A patch with excellent properties can be provided.

According to invention of Claim 2, in addition to the effect of Claim 1,
(1) Since the release sheet has a first cut and a second cut formed at intervals, and a part of the adhesive layer can be attached to the affected area and preliminarily fixed, If it is bad, it can be re-applied at the preliminary fixing stage, and a patch with excellent usability that can be reliably applied to the desired site of the affected area can be provided.
(2) A part of the adhesive layer can be affixed and fixed to the affected area before applying the entire surface of the adhesive layer. Can provide.

According to invention of Claim 3, in addition to the effect of Claim 1 or 2,
(1) Since the incision line has a main incision part and a cut-side extension part, the cut line is pushed up from the support side, and the tongue of the incision line formed by the main incision part and the cut-side extension part is It is possible to form a large finger-hanging hole with a large rise and a large cut line. For this reason, it is possible to provide a patch that can be easily peeled by holding the release sheet by firmly placing a finger on the finger-holding hole.
(2) When the tongue of the cut line that has been raised is folded back to the cut side of the release sheet, the thickness of the release sheet that has been lifted along the cut and the folded back of the tongue can be increased. If you pick up the part where the folded tongue pieces overlap with your finger, the release sheet will be difficult to slip through even between elderly people with weak fingertips, so you can easily peel the release sheet A patch can be provided.
(3) When the tongue of the cut line that has been raised is bent, a patch that can be easily picked up even when the release sheet is placed on a table or dropped on the floor can be provided.

According to invention of Claim 4, in addition to the effect of Claim 3,
(1) Since the outer extending portion is provided to extend to the main cut portion, the cut line is wide open and the finger hook hole is opened widely. A patch which can be easily grasped and peeled off can be provided.

According to invention of Claim 5, in addition to the effect of Claim 3 or 4,
(1) Since it has a parallel notch extending from the end of the cut side extending portion in a direction substantially parallel to the cut, etc., the cut side extending when the tongue of the cut line is raised or picked It is possible to provide a patch that can prevent a tear in the release sheet from the portion toward the cut, and can prevent the release sheet from tearing and the cut line from being connected to the cut.

According to invention of Claim 6, in addition to the effect of any one of Claims 3 to 5,
(1) Since it is provided with a fold line extending to the cut-side extension part or the parallel cut part, the tongue piece of the raised cut line can be easily folded or folded by the fold line. Is prevented from reattaching to the adhesive layer. For this reason, a series of peeling operation | movement can be performed smoothly and the patch which was remarkably excellent in handleability can be provided.

According to the invention described in claim 7, in addition to the effect of any one of claims 1 to 6,
(1) By containing a transdermally absorbable drug in the adhesive layer, a constant dose of the active ingredient can be absorbed through the skin while performing continuous and controlled control. Further, the drug concentration in the blood is maintained for a long period of time, and side effects can be reduced without burdening the digestive tract such as the stomach and intestine and the liver as in the case of oral preparations. In addition, it can be administered to elderly people and children, and it can be expected to have a safe and effective therapeutic effect. In addition, the use status of the drug can be confirmed at a glance, so the caregiver can understand the compliance status. Thus, it is possible to provide a patch having an excellent action and effect such as the expectation of advantages such as ease of use.

According to the invention described in claim 8, in addition to the effect of claim 7,
(1) Because the medicinal components of anti-inflammatory agents are absorbed through the skin and directly affect the inflamed muscles and joints, stiff shoulders, back pain, joint pain, muscle pain, bruises, sprains, tendonitis, elbow It is possible to provide a patch having an effect on pain and the like.

According to the invention described in claim 9, in addition to the effect of claim 7,
(1) The therapeutic agent for dementia, which is a medicinal component, can be safely and effectively passed through the skin by using the therapeutic agent for dementia that has been conventionally used as an oral preparation for transdermal absorption. Can be migrated to. Moreover, the patch which has the effect of being able to maintain a therapeutic effect over a long time can be provided.

Hereinafter, the best mode for carrying out the present invention will be described with reference to the drawings.
(Embodiment 1)
FIG. 1 is a plan view of the patch in the first embodiment of the present invention, FIG. 2 is a bottom view of the patch in the first embodiment, and FIG. 3 is a front view of the patch in the first embodiment. 4 is a left side view of the patch of the first embodiment, and FIG. 5 is a cross-sectional view taken along line XX of FIG.
In the figure, 1 is a patch in the first embodiment, 2 is a flexible support formed of a synthetic resin film, woven fabric, knitted fabric, nonwoven fabric or the like, and 3 is a support 2 mainly composed of a pressure-sensitive adhesive. The adhesive layer 4 is laminated on one side, 4 is a release sheet formed of a synthetic resin film or silicon-processed paper, and is attached to the entire surface of the adhesive layer 3, 5 is one edge of the release sheet 4, and 6 is an edge. 5, the other edge of the release sheet 4 opposite to 5 is formed in a wavy line extending from the one edge 5 to the other edge 6 and bisects the release sheet 4, and 8 is the divided release sheet 4 divided into two Cut lines 9 are formed on the left and right sides of the cut line 7 at positions where the distances from the edges 5 and 6 are substantially equal, and 9 is a main cut part of the cut line 8 formed in a straight line with a gap from the cut line 10. Extends in an arc from the end of the main cut 9 toward the cut 7 The cut-side extending portion 11 is formed as a parallel cut portion extending inwardly in a direction substantially parallel to the cut 7 from the end of the cut-portion extending portion 10, and 12 is formed inside the cut line 8 by a cut line 8. The tongue piece 13 is an edge portion of the release sheet 4 between the cut line 7 and the cut line 8.

Here, in the present embodiment, when A is the shortest distance from the cut 7 of the release sheet 4 to the end of the cut line 8 (parallel cut portion 11), A is 2 to 30 mm, preferably 3 to 25 mm. Preferably it is 5-20 mm. Moreover, when converted into a ratio with the length of the edge portions 5 and 6 of the release sheet 4, A is 1/50 to 1/5, preferably 3/100 to 3/20, of the length of the edge portions 5 and 6. Preferably it is formed in 1/20 to 1/10.
Further, when the width of the cut line 8 in the direction parallel to the edges 5 and 6 of the release sheet 4 (the width in the lateral direction) is B, B is 5 to 50 mm, preferably 10 to 35 mm, more preferably 12 to 25 mm. Is formed. Moreover, when converted into a ratio with the length of the edge portions 5 and 6 of the release sheet 4, B is 1/20 to 3/10, preferably 1/10 to 1/4 of the length of the edge portions 5 and 6. Preferably it is formed to 3/25 to 1/5.
Further, when the width of the cut line 8 in the direction orthogonal to the edges 5 and 6 of the release sheet 4 is C, C is 5 to 30 mm, preferably 7 to 25 mm, more preferably 10 to 20 mm. Is formed. C is formed at 1/14 to 6/7, preferably 1/10 to 5/14, more preferably 1/7 to 3/7, of the distance between the opposing edges 5 and 6 of the release sheet 4. Has been.
Moreover, when the shortest distance from the edge parts 5 and 6 of the peeling sheet 4 to the cut line 8 is set to D, D is formed 10 mm or more, Preferably it is 20 mm or more. Further, D is formed to be 1/7 or more, preferably 2/7 or more, of the length between the opposing edges 5 and 6 of the release sheet 4.

  In the patch 1 according to Embodiment 1 of the present invention configured as described above, an adhesive material having a pressure-sensitive adhesive as a main component is spread and applied to the release sheet 4, and then the adhesive material of the release sheet 4 is applied. It can be manufactured by bonding the surface and the support 2 and then forming the cut line 7 and the cut line 8 only in the release sheet 4.

Next, the usage method of the patch 1 in Embodiment 1 of this invention is demonstrated, referring drawings.
FIG. 6 is a diagram showing a state in which finger holes are formed in the patch in the first embodiment, and FIG. 7 is a diagram showing a state in which the tongue piece formed by the cut line of the patch in the first embodiment is bent. FIG. 8 is a diagram showing an example of the operation of applying the patch to the affected skin area in the first embodiment.
In the figure, 14 is a finger hole formed by pushing up the tongue 12 of the cut line 8 from the support 2 side, and 15 is a skin affected part.
First, the patch 1 is held and, as shown in FIG. 6, when the part where the cut line 8 of one of the divided release sheets 4 is formed is pushed up from the support 2 side with a finger, the tongue 12 of the cut line 8 is formed. Is pushed up and peeled off from the adhesive layer 3, and the cut line 8 is opened to form the finger hook hole 14. Next, as shown in FIG. 7, the tongue piece 12 is picked and bent at the position of the parallel cut portion 11 so that the finger hooking hole 14 is opened largely. In the same manner for the cut line 8 of the other halved release sheet 4, the tongue piece 12 is bent to form the finger hook hole 14.
Next, when the patch 1 is slightly bent along the cut line 7 of the release sheet 4, the cut line 7 is formed in a wavy shape, and therefore the edge portion 13 of the release sheet 4 extends along the cut line 7. From the surface. Tongue pieces that are bent from the front side of the release sheet 4 with another finger by putting a finger in between the edge portion 13 of the release sheet 4 that has been lifted up and the adhesive layer 3, placing a finger from the back side of the release sheet 4, 12 is put on the edge portion 13 so that the finger is put on the finger-holding hole 14, the fingers on the front side and the back side of the release sheet 4 are put together through the finger-holding hole 14, the release sheet 4 is picked, and a part of the release sheet 4 is peeled off. To expose a part of the adhesive layer 3. The exposed adhesive layer 3 is affixed to the skin affected part 15.
Next, as shown in FIG. 8, the finger-holding hole 14 of the release sheet 4 with a finger is pulled and slid along the surface of the skin affected area 15, and the release sheet 4 is gradually peeled off and applied to the patch 1. It is affixed to the skin affected part 15 so that it cannot be done.
Next, the patch 1 with the other release sheet 4 still attached to the adhesive layer 3 is bent slightly to cause the release sheet 4 to bend back, thereby sticking the edge portion 13 along the cut 7 of the release sheet 4. Elevate from layer 3. Tongue pieces that are bent from the front side of the release sheet 4 with another finger by putting a finger in between the edge portion 13 of the release sheet 4 that has been lifted up and the adhesive layer 3, placing a finger from the back side of the release sheet 4, The release sheet 4 is picked by placing a finger on the finger hole 14 so that 12 is overlapped with the edge portion 13. The picked hole 14 is pulled so as to slide along the surface of the skin affected area 15, and the release sheet 4 is gradually peeled off, and the patch 1 is applied to the skin affected area 15 so that the patch 1 is not wrinkled.

As described above, since the patch according to Embodiment 1 of the present invention is configured, the following effects can be obtained.
(1) Since the release sheet 4 is provided with the finger hooking holes 14 for hanging a part of the finger formed by the cut line 8 on the left and right of the cut line 7, the part where the cut line 8 is formed is formed from the support 2 side. Is pushed up, the tongue 12 of the cut line 8 is pushed up, peeled off from the adhesive layer 3 and the finger hooking hole 14 is opened. A finger is inserted between the edge portion 13 of the release sheet 4 that is lifted along the cut line 7 and the adhesive layer 3, the finger is put on the finger-holding hole 14, and the release sheet 4 is sandwiched by another finger so that the finger-holding hole is provided from the opposite side. When fingers are put on 14, the fingers come into contact with each other through the finger-holding holes 14, so that the release sheet 4 can be firmly picked up, and the finger is difficult to slip, so that the release sheet 4 can be easily peeled off.
(2) The surface of the release sheet 4 facing the adhesive layer 3 has been subjected to a release treatment such as silicon coating, and is very slippery due to the influence of the base component of the adhesive layer 3. Since the fingers picking up the release sheet 4 can be brought into contact with each other, the release sheet 4 can be firmly picked and peeled off without slipping.
(3) Since the tongue piece 12 of the cut line 8 adheres to the adhesive layer 3 and does not protrude before use, it is only necessary to form the cut line 7 and the cut line 8 on the release sheet 4 from the manufacturing aspect. Therefore, existing production equipment and materials can be used, and almost no new capital investment is required. Further, since there is no protruding portion on the release sheet 4, it is not caught on the edge of the device or the packaging bag, such as when being transported on the production line or when the patch 1 is accommodated in the packaging bag. The peeling sheet 4 is peeled off, the peeling sheet 4 is peeled off, and the exposed adhesive layer 3 is hardly attached, and the production line is not stopped or a defective product is not generated. The productivity is remarkably excellent.
(4) Since the tongue 12 of the score line 8 is attached to the adhesive layer 3 and does not protrude before use, it is not caught on the edge of the packaging bag when taken out from the packaging bag during use, and is smooth Easy to handle because it can be taken out easily.
(5) Since the cut line 8 includes the main cut part 9 and the cut side extending part 10, the cut line 8 is pushed up from the support 2 side and formed by the main cut part 9 and the cut side extended part 10. The tongue piece 12 of the cut line 8 can be raised largely, and the cut line 8 can be opened wide to form a large finger hook hole 14. For this reason, it is possible to easily peel off the release sheet 4 by holding the finger firmly on the finger-holding hole 14 and holding the release sheet 4.
(6) Since the cut-side extending portion 10 is provided, the tongue 12 of the raised cut line 8 can be folded back to the cut 7 side of the release sheet 4, and the release sheet 4 lifted along the cut 7. Since the edge portion 13 and the folded tongue piece 12 can be overlapped to increase the thickness, the fingertip force can be increased by grasping the edge portion 13 where the folded tongue piece 12 is overlapped by placing a finger on the finger hooking hole 14. Even the weak elderly person can hardly peel off the release sheet 4 from between the picked fingers, and therefore the release sheet 4 can be easily peeled off.
(7) If the tongue 12 of the cut line 8 is bent, the release sheet 4 can be easily picked up even when placed on a table or the like or dropped on the floor.
(8) Since the parallel cut portion 11 extending in the direction substantially parallel to the cut 7 is provided from the end of the cut side extending portion 10, the tongue piece 12 of the cut line 8 is raised or picked up. It is possible to prevent a tear from occurring in the release sheet 4 from the cut side extending portion 10 toward the cut 7, and to prevent the release sheet 4 from tearing and the cut line 8 from being connected to the cut 7. This is because, if the cut line 8 is connected to the cut line 7, it is difficult to detach the release sheet 4 by placing a finger on the finger hook hole 14.
(9) The shortest distance A from the cut 7 to the end of the cut line 8 (parallel cut portion 11) is 2 to 30 mm, preferably 3 to 25 mm, more preferably 5 to 20 mm, or the edge 5 , 6 of 1/50 to 1/5, preferably 3/100 to 3/20, more preferably 1/20 to 1/10. When lifted or picked, the release sheet 4 hardly rips from the end of the cut line 8 toward the cut line 7, and the finger hooking hole 14 can be reliably formed.
(10) The width (lateral width) B of the score line 8 in the direction parallel to the edges 5 and 6 of the release sheet 4 is 5 to 50 mm, preferably 10 to 35 mm, more preferably 12 to 25 mm. Alternatively, it is formed in 1/20 to 3/10, preferably 1/10 to 1/4, and more preferably 3/25 to 1/5 of the length of the edges 5 and 6, so Since the release sheet 4 is easy to peel off because it is easy to put a finger on the adhesive, and the area of the adhesive layer 3 exposed from the finger-holding hole 14 does not become too large, the adhesive layers 3 adhere to each other when the patch 1 is applied. 2 can be attached neatly without tangling.
(11) The width (longitudinal width) C of the cut line 8 in the direction orthogonal to the edges 5 and 6 of the release sheet 4 is 5 to 30 mm, preferably 7 to 25 mm, more preferably 10 to 20 mm. Or 1/14 to 6/7, preferably 1/10 to 5/14, more preferably 1/7 to 3/7 of the distance between the opposing edges 5 and 6 of the release sheet 4. Therefore, the release sheet 4 is easy to peel off because it is easy to put a finger on the finger hooking hole 14, and the area of the adhesive layer 3 exposed from the finger hooking hole 14 does not become too large. Can be attached neatly without sticking to the support 2.
(12) The shortest distance D from the edges 5 and 6 of the release sheet 4 to the cut line 8 is 10 mm or more, preferably 20 mm or more, or the length between the opposing edges 5 and 6 of the release sheet 4 Since the finger hole 14 formed by the cut line 8 is not too large, the adhesive layers 3 adhere to each other when the patch 1 is applied. Thus, the support 2 can be neatly attached without being entangled.

  Here, although the case where the cut line 7 is formed in a wavy line shape has been described in the present embodiment, a line formed in a linear shape, a sawtooth shape, or the like may be used. In this case, the same effect can be obtained.

(Embodiment 2)
FIG. 9 is a plan view of the patch according to Embodiment 2 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
Further, in the embodiments described below, except for the release sheet on which cut lines, cut lines, etc. are formed, they are the same as those described in the first embodiment, so only a plan view is described, and a bottom view and a front view are described. The figure, the left side view, and the cross-sectional view are omitted.
In the figure, 1a is a patch in Embodiment 2 of the present invention, and 16 is formed by extending from one edge 5 to the other edge 6 on the release sheet 4 outside the cut line 8 (opposite the cut 7). This is a fold line composed of a weakened line such as a perforated line, a groove, a broken line, or a line that is deteriorated by heating.

The patch 1a in the second embodiment can be used in the same manner as described in the first embodiment.
First, after the tongue 12 of the incision line 8 is raised to open the incision line 8 to form the finger hook hole 14, the finger is put in the finger hook hole 14 and the release sheet 4 is peeled off from the cut 7 side. When the release sheet 4 is peeled off to the position of the fold line 16, the release sheet 4 is bent along the fold line 16 due to the presence of the fold line 16, and the folded release sheet 4 is prevented from reattaching to the adhesive layer 3. The Next, if the patch 1a is pressed against the affected part in this state, the adhesive layer 3 is maintained in an exposed state, so that the patch 1a can be attached to the affected part and preliminarily fixed. And the release sheet 4 can peel from the adhesion layer 3 only by pulling the finger-holding hole 14 of the release sheet 4 with a finger, and at the same time, the entire adhesion layer 3 can be adhered to the skin.

As described above, since the patch in the second embodiment of the present invention is configured, in addition to the operation described in the first embodiment, the following operation can be obtained.
(1) Since the release sheet 4 is peeled off from the cut line 7 and the release sheet 4 is folded at the fold line 16 so that the exposed state of the adhesive layer 3 can be maintained, a part of the adhesive layer 3 is attached to the affected part in advance. Even when it is fixed, or when the patch 1a has to be applied with one hand, it can be easily applied without wrinkles.

(Embodiment 3)
FIG. 10 is a plan view of the patch according to Embodiment 3 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1b is a patch in Embodiment 3 of the present invention, 8b is a cut line formed on each of the left and right sides of the cut 7 of the divided release sheet 4, and 9b is a wavy line spaced from the cut 7 The main cut portion 10b of the formed cut line 8b is a cut side extending portion extending in an arc shape from the end of the main cut portion 9b toward the cut 7, and 11b is the end of the cut portion extending portion 10a. A parallel cut portion 12b extending inward in a direction substantially parallel to the cut line 7 is a tongue piece inside the cut line 8b.
The point in which the patch 1b in Embodiment 3 is different from Embodiment 1 is that the main cut portion 9b of the cut line 8b is formed in a wavy line shape.

As described above, since the patch in the second embodiment of the present invention is configured, in addition to the operation described in the first embodiment, the following operation can be obtained.
(1) Since the main incision 9b of the incision line 8b is formed in a wavy shape, the fingertip may be cut even when the fingertip rubs at the edge of the tongue 12b when the tongue 12b is raised. Excellent handleability.
(2) Since the main cut portion 9b is formed in a wavy line shape, when the patch 1b is slightly bent along the main cut portion 9b when the tongue piece 12b is raised, the tongue is formed along the main cut portion 9b. Since the piece 12b is lifted from the adhesive layer 3, the tongue piece 12b can be easily raised.

(Embodiment 4)
FIG. 11 is a plan view of a patch according to Embodiment 4 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 3 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1c is a patch in Embodiment 4 of the present invention, and 17 is a fold line extending from the parallel cut portion 11b and connecting the parallel cut portions 11b and 11b. The fold line 17 is formed by a weakened line such as a perforation, a groove, a broken line, or a line that is deteriorated by heating.

As described above, since the patch in the fourth embodiment is configured, the following action is obtained in addition to the action described in the first embodiment.
(1) Since the fold line 17 extended to the parallel cut portion 11b is provided, when the tongue piece 12b is raised, the tongue piece 12b bends along the fold line 17 due to the presence of the fold line 17 and adheres. Since reattachment to the layer 3 is prevented, it is possible to maintain a state in which the finger hooking hole is greatly opened, and it is possible to easily perform pasting and cleaning of the release sheet 4.

(Embodiment 5)
FIG. 12 is a plan view of the patch in the fifth embodiment of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1d is a patch according to Embodiment 5 of the present invention, 8d is a cut line formed on each of the left and right sides of the cut line 7, and 9d is formed in a curved shape that is gently protruded with a gap from the cut line 7. The main cut portion of the cut line 8d, 10d is a cut side extending portion extending linearly from the end of the main cut portion 9d toward the cut 7, and 11d is a cut from the end of the cut portion extending portion 10d. A parallel cut portion 12d extending inward in a direction substantially parallel to 7 is a tongue piece formed by a cut line 8d inside the cut line 8d.

As described above, since the patch in the fifth embodiment is configured, the following actions are obtained in addition to the actions described in the first embodiment.
(1) Since the main cut portion 9d of the cut line 8d is formed in a curved shape that protrudes, when the patch 1d is slightly bent along the main cut portion 9d when the tongue piece 12d is raised, Since the tongue piece 12d is easily lifted from the adhesive layer 3 along the cut portion 9d, the tongue piece 12d can be easily raised.

(Embodiment 6)
FIG. 13 is a plan view of a patch according to Embodiment 6 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1e is a patch in Embodiment 6 of the present invention, 7e is a straight line that extends from the edge 5 to the edge 6 of the release sheet 4 and bisects the release sheet 4, and 8e is the right and left of the cut 7e. A cut line 9e is formed in each of the cut lines 8e, and the cut line 8e is formed in a curvilinear shape with a gap between the cut line 7e and the cut line 8e. A cut-side extending portion 12e extending in an arc shape toward the inner side 12e is a tongue piece formed inside the cut line 8e.
The patch 1e in the sixth embodiment can also be used in the same manner as described in the first embodiment, and the same action as that described in the first embodiment can be obtained.

(Embodiment 7)
FIG. 14 is a plan view of a patch according to Embodiment 7 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1f is a patch according to Embodiment 7 of the present invention, 8f is a cut line formed on each of the left and right sides of the cut 7e, and 9f is a cut line formed in a concave curved line with a gap from the cut 7e. 8f is a main cut portion, 12f is a tongue formed inside the cut line 8f, and 18 is an outer extending portion extending in an arc shape from the end of the main cut portion 9f in the direction opposite to the cut 7e. .
Since the patch 1f in the seventh embodiment is similar to that described in the first embodiment, the tongue piece 12f can be raised to form a finger-holding hole, and the release sheet can be peeled off by placing a finger on this. The same effect as described in the first embodiment can be obtained.

(Embodiment 8)
FIG. 15 is a plan view of the patch in the eighth embodiment of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 7 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1 g is a patch in Embodiment 8 of the present invention, and 7 g is a cut line that is formed in a wavy shape extending from the edge 5 to the edge 6 of the release sheet 4 and bisects the release sheet 4.
The usage method and action of the patch 1g in the eighth embodiment are the same as those described in the seventh embodiment.

(Embodiment 9)
FIG. 16 is a plan view of a patch according to Embodiment 9 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1h is a patch in Embodiment 9 of the present invention, 8h is a cut line formed on each of the left and right sides of the cut 7e, and 9h is a cut line 8h formed in a straight line with a gap from the cut 7e. The main cut portion, 12h is a tongue formed inside the cut line 8h, and 18h is an outward extension that is bent from the end of the main cut portion 9h and extends in a straight line extending in the direction opposite to the cut 7e. It is an installation part.
The usage method and action of the patch 1h in the ninth embodiment are the same as those described in the seventh embodiment.

(Embodiment 10)
FIG. 17 is a plan view of the patch in the tenth embodiment of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1i is a patch in Embodiment 10 of the present invention, 8i is a cut line formed on each of the left and right sides of the cut 7e, and 9i is a cut line 8i formed in a straight line with a gap from the cut 7e. The main cut portion 10i is a straight side extending portion that is bent from the end of the main cut portion 9i and expands in the direction of the cut 7e, and 12i is formed inside the cut line 8i. Tongue piece.
The patch 1i in the tenth embodiment can also be used in the same manner as described in the first embodiment, and the same action as that described in the first embodiment can be obtained.

(Embodiment 11)
FIG. 18 is a plan view of a patch according to Embodiment 11 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1j is a patch in Embodiment 11 of the present invention, 8j is a cut line formed on each of the left and right of the cut 7e of the divided release sheet 4, and 9j is linearly spaced from the cut 7e. The main cut portion 10j of the formed cut line 8j is a cut side extending portion extending in an arc shape from the end of the main cut portion 9j toward the cut 7e, and 11j is the end of the cut portion extending portion 10j. A parallel cut portion 12j extending inward in a direction substantially parallel to the cut line 7e, 12j is a tongue piece formed inside the cut line 8j.
The patch 1j in the eleventh embodiment can also be used in the same manner as described in the first embodiment, and the same action as that described in the first embodiment can be obtained.

(Embodiment 12)
FIG. 19 is a plan view of a patch according to Embodiment 12 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1k is a patch according to the twelfth embodiment of the present invention, 8k is a cut line formed on each of the left and right of the cut 7e of the divided release sheet 4, and 9k is curved with a gap from the cut 7e. A main cut portion 10k of the formed cut line 8k is a cut side extending portion extending in an arc shape from the end of the main cut portion 9k toward the cut 7e, and 17k is a terminal end of the cut portion extending portion 10k. This is a fold line extending substantially parallel to the cut line 7e and connecting the cut line extending parts 10k, 10k. The fold line 17k is formed by a weakening line such as a perforation, a groove, a broken line, or a line that is deteriorated by heating.
The patch 1k in the twelfth embodiment can be used in the same manner as described in the first and fourth embodiments, and the same action as that described in the first and fourth embodiments can be obtained.

(Embodiment 13)
FIG. 20 is a plan view of a patch according to Embodiment 13 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, reference numeral 1l denotes a patch according to the thirteenth embodiment of the present invention, 8l denotes cut lines formed on the left and right sides of the cut 7e, and 9l denotes a cut line formed in a concave curved line with a gap from the cut 7e. 8l main incision part, 12l is a tongue formed inside the incision line 8l, 18l is an outer extension part extending in an arc shape from the end of the main incision part 9l in the direction opposite to the cut 7e, 19 Is a fold line extending substantially parallel to the cut 7e at the end of the outer extending portion 18l and connecting the outer extending portions 18l and 18l. The fold line 18l is formed by a weakened line such as a perforation, a groove, a broken line, or a line that is deteriorated by heating.
Since the patch 1l in the thirteenth embodiment is similar to the one described in the first embodiment, the tongue piece 12l can be raised to form a finger-holding hole, and the release sheet can be peeled off by placing a finger on this, The same effect as described in the first embodiment can be obtained. Further, since the folding line 19 is formed, the raised tongue piece 12l is bent along the folding line 19 and prevented from reattaching to the adhesive layer 3, so that the state where the finger hooking hole is largely opened is maintained. Thus, it is possible to easily perform pasting and cleaning of the release sheet 4.

(Embodiment 14)
FIG. 21 is a plan view of a patch according to Embodiment 14 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1 m is a patch in Embodiment 14 of the present invention, 8 m is a cut line formed on each of the left and right sides of the cut 7 e of the divided release sheet 4, and 9 m is linearly spaced from the cut 7 e. The main cut portion of the formed cut line 8m, 10m is a cut-side extending portion extending in a straight tapered shape from the end of the main cut portion 9m toward the cut 7e, and 12m is a cut line 8m. It is the tongue piece formed inside.
The patch 1m in the fourteenth embodiment can be used in the same manner as that described in the first embodiment, and the same action as that described in the first embodiment can be obtained.

(Embodiment 15)
FIG. 22 is a plan view of the patch in the fifteenth embodiment of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1n is a patch in the fifteenth embodiment of the present invention, 8n is a cut line formed on each of the left and right sides of the cut 7e, and 9n is a cut line 8n formed in a wavy line with a gap from the cut 7e. The main cut portion 10n is a cut side extending portion that extends in a straight tapered shape from the end of the main cut portion 9n toward the cut 7e, and 12n is a tongue formed inside the cut line 8n. The pieces 17n are extended substantially parallel to the cuts 7e at the ends of the cut part extending parts 10n, and the perforations, grooves, cut lines, and heating connecting the cut part extending parts 10n and 10n are deteriorated by heating. This is a fold line formed by a weakening line such as a broken line.
The patch 1n in the fifteenth embodiment can be used in the same manner as described in the first or fourth embodiment, and the same action as that described in the first or fourth embodiment is obtained.

(Embodiment 16)
FIG. 23 is a plan view of a patch according to Embodiment 16 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 6 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1o is a patch according to the sixteenth embodiment of the present invention, 8o is a cut line formed in a straight line substantially parallel to the cut 7e on each of the left and right sides of the cut 7e, and 13o is a cut line 8o and a cut 7e. It is the edge part of the peeling sheet 4 in between.

Next, the usage method of the patch 1o in Embodiment 16 is demonstrated.
When the patch 1o is picked up and the part where the cut line 8o of the one release sheet 4 divided into two by the cut 7e is pushed up from the support 2 side with the finger, the edge part 13o of the release sheet 4 is pushed up. It peels off from the adhesive layer and floats up, and a cut line 8o is opened to form a finger hooking hole. Next, hook the finger from the front side of the release sheet 4 to the finger-holding hole formed by lifting the edge portion 13o, and insert another finger from the back side of the release sheet 4 to hook the finger to the finger-holding hole, and the front side of the release sheet 4 And the fingers on the back side are put together through the finger-holding holes, the release sheet 4 is picked, a part of the release sheet 4 is peeled off to expose the adhesive layer, and is attached to the affected skin area. The other release sheet 4 is peeled in the same manner, and the adhesive layer is exposed and affixed to the affected skin area.
Since the patch 1o in the sixteenth embodiment is configured as described above, the same action as that described in the first embodiment can be obtained.

(Embodiment 17)
FIG. 24 is a plan view of a patch according to Embodiment 17 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1p is a patch in Embodiment 17 of the present invention, 8p is a cut line formed in a wavy shape substantially parallel to the cut 7 on each of the left and right sides of the cut 7, and 13p is a cut line 8p. This is the edge portion of the release sheet 4 between the cut line 7.

Here, in the present embodiment, the shortest distance A from the cut 7 of the release sheet 4 to the cut line 8p is 2 to 30 mm, preferably 3 to 25 mm, more preferably 5 to 20 mm. Moreover, when converted into a ratio with the length of the edge portions 5 and 6 of the release sheet 4, A is 1/50 to 1/5, preferably 3/100 to 3/20, of the length of the edge portions 5 and 6. Preferably it is formed in 1/20 to 1/10.
The width (longitudinal width) C of the cut line 8p in the direction orthogonal to the edges 5 and 6 of the release sheet 4 is 5 to 30 mm, preferably 7 to 25 mm, more preferably 10 to 20 mm. C is formed at 1/14 to 6/7, preferably 1/10 to 5/14, more preferably 1/7 to 3/7, of the distance between the opposing edges 5 and 6 of the release sheet 4. Has been.
The shortest distance D from the edge portions 5 and 6 of the release sheet 4 to the cut line 8p is 10 mm or more, preferably 20 mm or more. Further, D is formed to be 1/7 or more, preferably 2/7 or more, of the length between the opposing edges 5 and 6 of the release sheet 4.

  The patch 1p in the seventeenth embodiment can also be used in the same manner as described in the sixteenth embodiment, and the same action as that described in the first embodiment can be obtained.

(Embodiment 18)
FIG. 25 is a plan view of the patch according to the eighteenth embodiment of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1q is a patch in Embodiment 18 of the present invention, 8q is a cut line formed in a wavy shape substantially parallel to the cut line 7 on each of the left and right sides of the cut line 7, and 13q is a cut line 8q. This is the edge portion of the release sheet 4 between the cut line 7.
The patch 1q in the eighteenth embodiment can also be used in the same manner as described in the sixteenth embodiment, and the same action as that described in the first embodiment can be obtained.

(Embodiment 19)
FIG. 26 is a plan view of a patch according to Embodiment 19 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1r is the patch of the nineteenth embodiment, 8r is a cut line formed in a substantially I shape on each of the left and right sides of the cut 7, and 9r is a straight line that is substantially parallel to the cut 7 with a gap from the cut 7. The main cut portion 10r of the cut line 8r formed in a shape is a cut side extending portion extending in a straight line substantially perpendicular to the main cut portion 9r from the end of the main cut portion 9r toward the cut 7; 12r is a tongue formed on the inside of the cut line 8r, and 18r is an outer extending portion extending in a straight line substantially perpendicular to the main cut portion 9r from the end of the main cut portion 9r toward the opposite direction of the cut 7. It is.
Here, in the present embodiment, A is the shortest distance from the cut 7 of the release sheet 4 to the end of the cut line 8r (the cut-side extending portion 10r) is 2 to 30 mm, preferably 3 to 25 mm, more preferably Is formed to 5 to 20 mm. Moreover, when converted into a ratio with the length of the edge portions 5 and 6 of the release sheet 4, A is 1/50 to 1/5, preferably 3/100 to 3/20, of the length of the edge portions 5 and 6. Preferably it is formed in 1/20 to 1/10.
Further, the width (lateral width) B of the cut line 8r in the direction parallel to the edges 5 and 6 of the release sheet 4 is 5 to 50 mm, preferably 10 to 35 mm, more preferably 12 to 25 mm. Moreover, when converted into a ratio with the length of the edge portions 5 and 6 of the release sheet 4, B is 1/20 to 3/10, preferably 1/10 to 1/4 of the length of the edge portions 5 and 6. Preferably it is formed to 3/25 to 1/5.
The width (longitudinal width) C of the cut line 8r in the direction orthogonal to the edges 5 and 6 of the release sheet 4 is 5 to 30 mm, preferably 7 to 25 mm, more preferably 10 to 20 mm. C is formed at 1/14 to 6/7, preferably 1/10 to 5/14, more preferably 1/7 to 3/7, of the distance between the opposing edges 5 and 6 of the release sheet 4. Has been.
Further, the shortest distance D from the edge portions 5 and 6 of the release sheet 4 to the cut line 8r is 10 mm or more, preferably 20 mm or more. Further, D is formed to be 1/7 or more, preferably 2/7 or more, of the length between the opposing edges 5 and 6 of the release sheet 4.
The patch 1r in the nineteenth embodiment can be used in the same manner as described in the first embodiment.

As described above, since the patch in the nineteenth embodiment is configured, the following operation is obtained in addition to the operation described in the first embodiment.
(1) Since the outer extending portion 18r extending to the main notch portion 9r is provided, the notch line 8r is opened widely and the finger hooking hole is opened widely. Thus, the release sheet 4 can be gripped and easily peeled off.

(Embodiment 20)
FIG. 27 is a plan view of a patch according to Embodiment 20 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1 s is a patch in the embodiment 20, 8 s is a cut line formed in a substantially H shape on each of the left and right sides of the cut 7, and 9 s is a straight line that is substantially parallel to the cut 7 with a gap from the cut 7. The main cut portion 10s of the cut line 8s formed in a shape is a cut side extending portion extending in a straight line substantially perpendicular to the main cut portion 9s from the approximate center of the main cut portion 9r toward the cut 7. , 11 s is a parallel cut portion formed in a straight line substantially parallel to the cut 7 from the end of the cut portion extending portion 10 s toward the edges 5 and 6 of the release sheet 4.
As described above, since the patch of the twentieth embodiment is configured, the same action as the patch of the nineteenth embodiment is obtained.

(Embodiment 21)
FIG. 28 is a plan view of a patch according to Embodiment 21 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1t is the patch in the embodiment 21, 8t is a cut line formed in a substantially cross shape on each of the left and right sides of the cut 7, and 9t is a straight line substantially parallel to the cut 7 with a gap from the cut 7. The main cut portion 10t of the cut line 8t formed in a shape is a cut side extending portion extending in a straight line substantially perpendicular to the main cut portion 9t from the approximate center of the main cut portion 9t toward the cut 7 , 18t is an outwardly extending portion extending in a straight line substantially perpendicular to the main cut portion 9t from the approximate center of the main cut portion 9t in the direction opposite to the cut line 7.
As described above, since the patch of the twenty-first embodiment is configured, the same action as the patch of the nineteenth embodiment is obtained.

(Embodiment 22)
FIG. 29 is a plan view of a patch according to Embodiment 22 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1u is a patch in the embodiment 22, 8u is a cut line formed in a substantially I shape on each of the left and right sides of the cut 7, and 9u is a straight line substantially parallel to the cut 7 with a gap from the cut 7. The main cut portion of the cut line 8u formed in a shape, 10u is a cut side extending portion extending in a straight line extending from both ends of the main cut portion 9u toward the cut 7, and 18u is the main cut It is the outer side extension part extended in the linear form expanded from the both ends of the part 9u toward the direction opposite to the cut | interruption 7. FIG.
As described above, since the patch in the twenty-second embodiment is configured, the same action as the patch in the nineteenth embodiment is obtained.

(Embodiment 23)
FIG. 30 is a plan view of a patch according to Embodiment 23 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1v is the patch in the embodiment 23, 8v is a cut line formed on each of the left and right sides of the cut line 7, and 9v is a main of the cut line 8v formed in a gentle curve spaced from the cut line 7. The notches 18v are outer extending portions extending in a straight line extending from both ends of the main notch 9v in the direction opposite to the cut 7.
As described above, since the patch in the twenty-third embodiment is configured, the same action as the patch in the seventh embodiment is obtained.

(Embodiment 24)
FIG. 31 is a plan view of a patch according to Embodiment 24 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1w is a patch in Embodiment 24 of the present invention, 20 is a linear first cut extending from the edge 5 of the release sheet 4 to the other edge 6 facing, and 21 is a distance from the first cut 20. A second cut extending from the edge 5 of the release sheet 4 to the edge 6 in a substantially parallel manner, 22 is a strip of the release sheet 4 divided by the first cut 20 and the second cut 21, and 8w is the first cut. A wavy line formed on each of the left side of 20 and the right side of the second cut 21, 13 w is an edge portion of the release sheet 4 between the cut lines 8 w and 8 w and the first cut 20 and the second cut 21. .
In this Embodiment, the width | variety (interval of the 1st cut 20 and the 2nd cut 21) of the strip | belt part 22 is formed in 10-30 mm by the shortest distance.

Next, the usage method of the patch 1w in Embodiment 24 is demonstrated.
First, the band part 22 of the release sheet 4 of the patch 1w is picked and peeled with a finger. Next, the adhesive layer 3 exposed by peeling of the band portion 22 is stuck to the affected skin area, and the patch 1w is preliminarily fixed.
Next, as described in the sixteenth embodiment, when the portion where the cut line 8w is formed is pushed up from the support 2 side with a finger, the edge portion 13w is peeled off from the adhesive layer and lifted up, and the cut line 8w is lifted. Opens to form a finger hooking hole. Next, a finger is put on the finger-holding hole from the front side of the release sheet 4, another finger is inserted from the back side of the release sheet 4, and the finger is put on the finger-holding hole. In addition, the release sheet 4 is picked, and the release sheet 4 is peeled off and attached to the affected skin area. The other release sheet 4 is also peeled off in the same manner and applied to the affected skin area.

As described above, since the patch in the twenty-fourth embodiment is configured, the following actions are obtained in addition to the actions described in the first embodiment.
(1) Since it has the 1st cut 20 and the 2nd cut 21 formed at intervals, a part of adhesive layer exposed by peeling of the belt | band | zone part 22 is stuck to an affected part, and it fixes beforehand. Therefore, if the application site is bad, it can be applied again at the preliminary fixing stage, and it can be reliably applied to the desired site of the affected area.
(2) Since a part of the adhesive layer can be affixed and fixed to the affected area before the entire surface of the adhesive layer is affixed, it is difficult to slip when the remaining release sheet 4 is peeled off, and it can be easily affixed neatly with one hand.

(Embodiment 25)
FIG. 32 is a plan view of a patch according to Embodiment 25 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 and Embodiment 24 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1x is a patch in Embodiment 25 of the present invention, 20x is a wavy first cut extending from the edge 5 of the release sheet 4 to the opposite edge 6 and 21x is spaced from the first cut 21x. This is a wavy second cut extending from the edge 5 to the edge 6 of the release sheet 4 in a substantially parallel manner.

Here, in the present embodiment, the shortest distance A from the first cut 20x (or the second cut 21x) of the release sheet 4 to the cut line 8w is 2 to 30 mm, preferably 3 to 25 mm, more preferably 5 It is formed to ˜20 mm. Moreover, when converted into a ratio with the length of the edge portions 5 and 6 of the release sheet 4, A is 1/50 to 1/5, preferably 3/100 to 3/20, of the length of the edge portions 5 and 6. Preferably it is formed in 1/20 to 1/10.
The width (longitudinal width) C of the cut line 8w in the direction orthogonal to the edges 5 and 6 of the release sheet 4 is 5 to 30 mm, preferably 7 to 25 mm, more preferably 10 to 20 mm. C is formed at 1/14 to 6/7, preferably 1/10 to 5/14, more preferably 1/7 to 3/7, of the distance between the opposing edges 5 and 6 of the release sheet 4. Has been.
The shortest distance D from the edge portions 5 and 6 of the release sheet 4 to the cut line 8w is 10 mm or more, preferably 20 mm or more. Further, D is formed to be 1/7 or more, preferably 2/7 or more, of the length between the opposing edges 5 and 6 of the release sheet 4.

  As described above, since the patch in the twenty-fifth embodiment is configured, in addition to the operation described in the twenty-fifth embodiment, the first cut 20x and the second cut 21x are formed in a wavy line. The edge part of the part 22 can be easily turned and the strip part 22 can be easily peeled off.

(Embodiment 26)
FIG. 33 is a plan view of the patch according to Embodiment 26 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 24 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1y is a patch in Embodiment 26 of the present invention, 8y is a semicircular cut line formed on each of the left side of the first cut 20 and the right side of the second cut 21, and 9y is the first cut 20 And the second cut line 21 and the main cut part 10y of the cut line 8y formed in a curvilinear shape with a distance from the first cut 20 or the second cut 21 from the end of the main cut part 9y. It is the cut | interruption side extension part extended in the arc shape toward the direction.
The patch 1y in Embodiment 26 can also be used in the same manner as described in Embodiment 24, and the same action as that described in Embodiment 24 and Embodiment 1 can be obtained.

(Embodiment 27)
FIG. 34 is a plan view of a patch according to Embodiment 27 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1, 24,26 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1z is the patch in embodiment 27 of the present invention, 16z is the release sheet 4 on the outside of the cut line 8y (opposite side of the first cut 20 or the second cut 21) from one edge 5 to the other. It is a fold line made of a weakening line such as a perforation, a groove, a broken line, and a line that is heated to deteriorate the release sheet 4 formed extending to the edge 6.
The patch 1z in Embodiment 27 can also be used in the same manner as that described in Embodiment 24, and the same action as that described in Embodiment 24 and Embodiment 1 can be obtained. In addition, since the exposed state of the adhesive layer 3 can be maintained by folding the release sheet 4 at the fold line 16z, a part of the adhesive layer 3 is attached to the affected part and preliminarily fixed, or the patch 1z is used with one hand. Even when it is necessary to affix, it can be affixed easily and without wrinkles.

(Embodiment 28)
FIG. 35 is a plan view of a patch according to Embodiment 28 of the present invention.
In the figure, 1α is a patch according to Embodiment 28 of the present invention. Others are the same as those described in Embodiments 1, 25, and 26, so the same reference numerals are given and description thereof is omitted.
The patch 1α in the embodiment 28 can also be used in the same manner as described in the embodiment 24, and the same operation as that described in the embodiment 24 and the embodiment 1 can be obtained.

(Embodiment 29)
FIG. 36 is a plan view of a patch according to Embodiment 29 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1, 24,26 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1β is the patch in the embodiment 29 of the present invention, 16β is the release sheet 4 on the outside of the cut line 8y (opposite the first cut 20x or the second cut 21x) from one edge 5 to the other. It is a fold line made of weakening lines such as perforations, grooves, cut lines, lines that are formed by extending to the edge 6, and lines that are deteriorated by heating.
The patch 1β in the embodiment 29 can also be used in the same manner as described in the embodiment 24, and the same operation as that described in the embodiment 24 and the embodiment 1 can be obtained. In addition, since the exposed state of the adhesive layer 3 can be maintained by folding the release sheet 4 along the fold line 16β, a part of the adhesive layer 3 is attached to the affected part and preliminarily fixed, or the patch 1β is used with one hand. Even if it is necessary to affix, it can be affixed easily and without wrinkles.

Embodiment 30
FIG. 37 is a plan view of a patch according to Embodiment 30 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1 or 26 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1γ is a patch in the embodiment 30 of the present invention, 7γ is a cut line that bisects the release sheet 4 that is formed in an S shape while being largely bent from one edge 5 to the other edge 6. It is.
In the present embodiment, the distance from the edges 5 and 6 of the release sheet 4 of the score line 8y is different from the previous embodiments, but is the same as the patch described in the first embodiment. The same effect can be obtained.

Embodiment 31
FIG. 38 is a plan view of a patch according to Embodiment 31 of the present invention. In addition, the thing similar to what was demonstrated in Embodiment 1, 26,30 attaches | subjects the same code | symbol, and abbreviate | omits description.
In the figure, 1δ is a patch in the embodiment 31 of the present invention, 16δ is formed on the release sheet 4 outside the cut line 8y (opposite the cut 7γ) from one edge 5 to the other edge 6. This is a fold line composed of a weakened line such as a perforated line, a groove, a broken line, or a line that is deteriorated by heating.
The patch 1δ in Embodiment 31 can be used in the same manner as the patch described in Embodiment 2, and the same action is obtained.

EXAMPLES Hereinafter, although an Example is given and this invention is demonstrated concretely, this invention is not restrict | limited to these Examples at all.
(Test Example 1)
When creating and applying the patches of Examples and Comparative Examples, “Ease of grasping release sheet”, “Ease of application”, “When the release sheet was peeled off and placed on a flat table. A comparative test was conducted on “ease of grasping the release sheet”.
Example 1
Styrene-isoprene-styrene block copolymer (hereinafter referred to as SIS) 20% by mass, liquid paraffin 50% by mass, polyisobutylene (hereinafter referred to as PIB) 7% by mass, Alcon P-100 15% by mass and 2% by mass of butylhydroxytoluene (hereinafter referred to as BHT) was heated and mixed, then 1% by mass of indomethacin, 2% by mass of L-menthol and 3% by mass of crotamiton were added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, the cut line and the cut line having the shape described in Embodiment 1 (FIG. 1) were formed on a release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a score line was A: 5mm, B: 12mm, C: 20mm, D: 25mm.

(Example 2)
21% by mass of SIS, 49% by mass of liquid paraffin, 6% by mass of PIB, 12% by mass of Alcon P-100 and 2% by mass of BHT were heated and mixed, and then 3% by mass of flurbiprofen and L-menthol 3 Mass% and crotamiton 4 mass% were added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, cuts and cut lines having the shapes described in Embodiment 12 (FIG. 19) were formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a cut line was A: 7mm, B: 15mm, C: 15mm, D: 27.5mm.

(Example 3)
20% by mass of SIS, 50% by mass of liquid paraffin, 7% by mass of PIB, 13% by mass of Alcon P-100 and 2% by mass of BHT, and then 3% by mass of ketoprofen, 2% by mass of L-menthol and 3% by mass of crotamiton was added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, cuts and cut lines having the shapes described in Embodiment 28 (FIG. 35) were formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a cut line was A: 10mm, B: 10mm, C: 20mm, D: 25mm.

Example 4
20% by mass of SIS, 50% by mass of liquid paraffin, 7% by mass of PIB, 15% by mass of Alcon P-100, and 2% by mass of BHT were heated and mixed, and then 1% by mass of felbinac, 2% by mass of L-menthol and 3% by mass of crotamiton. % And kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, the cut line and the cut line having the shape described in Embodiment 1 (FIG. 1) were formed on a release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a score line was A: 5mm, B: 12mm, C: 20mm, D: 25mm.

(Example 5)
SIS is 24% by mass, liquid paraffin is 50% by mass, PIB is 6% by mass, Alcon P-100 is 12% by mass, and BHT is 2% by mass. Next, loxoprofen sodium is 3% by mass, L-menthol is 3% by mass. And kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, cuts and cut lines having the shapes described in Embodiment 17 (FIG. 24) were formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. In addition, the dimensions for specifying the cut line were A (the shortest distance between waves between the cut line formed in the wavy line and the cut line formed in the wavy line): 7 mm, C: 20 mm, and D: 25 mm. .

(Example 6)
20% by mass of SIS, 48% by mass of liquid paraffin, 6% by mass of PIB, 15% by mass of Alcon P-100, and 1% by mass of BHT were heated and mixed, and then kneaded with 7% by mass of glycol salicylate and 3% by mass of L-menthol. A uniform melt was obtained. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, cuts and cut lines having the shapes described in Embodiment 25 (FIG. 32) were formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. The dimensions for specifying the cut line are A (the shortest distance between waves between the cut line formed in a wavy line and the cut line formed in a wavy line): 5 mm, C: 25 mm, D: 22.5 mm there were.

(Example 7)
21 mass% SIS, 49 mass% liquid paraffin, 7 mass% PIB, 12 mass% Alcon P-100 and 2 mass% BHT were heated and mixed, then diclofenac sodium 3 mass%, L-menthol 3 mass% Further, 3% by mass of crotamiton was added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, cuts and cut lines having the shapes described in Embodiment 6 (FIG. 13) were formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a cut line was A: 7mm, B: 13mm, C: 15mm, D: 27.5mm.

(Example 8)
21% by mass of SIS, 47% by mass of liquid paraffin, 8% by mass of PIB, 15% by mass of Alcon P-100 and 1% by mass of BHT were heated and mixed, and then 5% by mass of loxoprofen sodium, 2% by mass of L-menthol and crotamiton 1 Mass% was added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, the cut line and the cut line having the shape described in Embodiment 1 (FIG. 1) were formed on a release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a score line was A: 5mm, B: 12mm, C: 20mm, D: 25mm.

Example 9
21% by mass of SIS, 49% by mass of liquid paraffin, 7% by mass of PIB, 12% by mass of Alcon P-100 and 1% by mass of BHT were heated and mixed, and then 3% by mass of felbinac, 3% by mass of L-menthol and 4% by mass of polyethylene glycol (Macrogol 1000) was added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, cuts and cut lines having the shapes described in Embodiment 12 (FIG. 19) were formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a score line was A: 7mm, B: 12mm, C: 16mm, D: 27mm.

(Example 10)
18.5% by mass of SIS, 30.5% by mass of liquid paraffin, 7.5% by mass of PIB, 32.5% by mass of Alcon P-100 and 1% by mass of BHT, and then 3% by mass of donepezil hydrochloride %, L-menthol 1% by mass and polyethylene glycol (Macrogol 1000) 5% by mass were added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, cuts and cut lines having the shapes described in Embodiment 12 (FIG. 19) were formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a cut line was A: 5mm, B: 15mm, C: 18mm, D: 26mm.

(Example 11)
SIS 20% by mass, liquid paraffin 35% by mass, PIB 8% by mass, Alcon P-100 29% by mass and BHT 2% by mass, then rivastigmine 1% by mass, L-menthol 2% by mass and crotamiton 3% by mass The mixture was kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, the cut line and the cut line having the shape described in Embodiment 1 (FIG. 1) were formed on a release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm. Moreover, the dimension which specifies a score line was A: 5mm, B: 12mm, C: 20mm, D: 25mm.

(Comparative example)
In the same manner as in Example 1, 20% by mass of SIS, 50% by mass of liquid paraffin, 7% by mass of PIB, 15% by mass of Alcon P-100 and 2% by mass of BHT were heated and mixed, and then 1% by mass of indomethacin, 2% by mass of L-menthol and 3% by mass of crotamiton were added and kneaded to obtain a uniform melt. Using a doctor knife plaster, the melt obtained was spread and applied to a release sheet (thickness 70 μm) made of silicon-treated polyester terephthalate at 100 g / m ² , and then a nonwoven fabric made of polyethylene terephthalate on the coated surface A support consisting of was laminated. Next, only the cut having the shape described in Embodiment 1 (FIG. 1) (no cut line was provided) was formed on the release sheet to obtain a patch. The width of the patch was 100 mm, and the vertical length was 70 mm.

(Peeling and sticking test)
Ten healthy adults 40 to 75 years old (A to J) apply the patches of Examples 1 to 11 and Comparative Examples, and “Ease of grasping release sheet” and “Easy to apply” ”And“ Ease of grasping the release sheet when placing the peeled release sheet on a flat table after sticking (ease of tidying up) ”was scored according to the following evaluation criteria based on the comparative example. .
The evaluation criteria were as follows.
(1) Ease of gripping the release sheet 3: Very easy to grip compared to the comparative example 2: Easy to grip compared to the comparative example 1: Same as the comparative example.
(2) Ease of application 3: Easy to apply compared to the comparative example 2: Easy to apply compared to the comparative example 1: Same as the comparative example.
(3) Ease of grasping the release sheet placed on the table (easy to clean up)
3: Very easy to grip compared to the comparative example, 2: Easy to grip compared to the comparative example, 1: Same as the comparative example.
In Table 1, “Ease of gripping release sheet (expressed as“ Ease of gripping ”)”, “Ease of sticking (denoted as“ attachment ”)”, “After peeling, peel off the release sheet on a flat table. The average value of the scoring of 10 people about the ease of grasping of the release sheet when placed (denoted as “cleaning up”) is shown. In addition, since the scoring of a comparative example is 1, if the average value is a value larger than 1, it has shown that it is superior to a comparative example.

  As described above, according to this example, the release sheet is very easy to grasp and can be easily peeled off from the support, and is easy to stick. Further, after sticking, the peeled release sheet is peeled off when placed on a flat table. It became clear that it was easy to grip the sheet, so it was easy to clean up.

(Test Example 2)
A plurality of patches having the shape described in Embodiment 1 (FIG. 1) were prepared in the same manner as in Example 1. When forming a score line on a release sheet having a thickness of 70 μm, 10 patches each having the same dimension B: 10 mm, C: 20 mm, D: 25 mm and changing only the dimension A are specified. Created. The dimensions A were (1) 1 mm, (2) 2 mm, (3) 3 mm, and (4) 5 mm. The width of the patch was 100 mm, and the vertical length was 70 mm.
A test was performed in which each of the prepared 10 patches (1) to (4) was applied to the upper arm, and it was examined whether or not a tear occurred at the edge of the release sheet from the score line. The results were as follows.
Patch (1): Six out of ten sheets were cut by tearing the edge of the release sheet. In four sheets, a slight tear occurred from the score line.
(2) Patch: 2 out of 10 sheets were cut by tearing the edge of the release sheet. In four sheets, a slight tear occurred from the score line. The two sheets had no tears from the score line.
Patch of (3): 3 out of 10 had slight tears from the score line. Seven sheets had no tears from the score line.
(4) Patch: 1 of 10 sheets had a slight tear from the score line. Nine sheets had no tears from the score line.
As described above, according to this test example, it was revealed that if the dimension A from the cut line to the cut line is 5 mm or more, the strength of the edge portion of the release sheet can be sufficiently secured.

(Test Example 3)
A plurality of patches having the shape described in Embodiment 19 (FIG. 26) were prepared in the same manner as in Example 1. When forming the cut lines, the dimensions A: 5 mm and B: 20 mm for specifying the cut lines were the same, and five patches each having different dimensions C and D were prepared. The dimensions C and D were (1) 64 mm and 3 mm, (2) 60 mm and 5 mm, (3) 50 mm and 10 mm, (4) 40 mm and 15 mm, and (5) 24 mm and 23 mm. The width of the patch was 100 mm, and the vertical length was 70 mm.
A test was conducted to apply the five prepared patches (1) to (5) to the upper arm, and it was examined whether they could be applied neatly. The results were as follows.
Patch of (1): The release sheet was bent in all 5 sheets, the adhesive layers were stuck together, and the support was entangled and could not be applied neatly.
The patch of (2): One sheet could not be applied neatly because the release sheet was bent and the adhesive layers were stuck together and the support was entangled. The four sheets took some time but managed to stick.
Patch (3): Although wrinkles occurred on the support, all 5 sheets could be applied.
Patch (4): Although some wrinkles occurred on the support, all 5 sheets could be pasted.
(5) Patch: All 5 sheets could be applied smoothly.
As described above, according to this test example, it has been clarified that if the dimension D from the edge of the release sheet to the cut line is 20 mm or more, it can be applied neatly without wrinkles.

  The present invention relates to a patch such as plaster (plaster) and the like, and it is easy to peel off a peeling sheet firmly with a finger that is difficult to slip, has excellent peeling workability, and utilizes existing production equipment and materials. Product can be manufactured and requires almost no new capital investment, and since there is no protruding part on the release sheet, the release sheet is caught during manufacturing, and problems such as production line stoppage and generation of defective products do not occur. In addition, it is possible to provide a patch which can be removed smoothly even when taken out from a packaging bag at the time of use and has excellent handleability. Furthermore, by including a transdermally absorbable drug in the adhesive layer, even elderly people with weak finger strength can peel off the release sheet themselves and apply them smoothly to the skin, while controlling a certain amount of active ingredients. A patch that can be continuously percutaneously absorbed and administered can be provided.

Plan view of patch in embodiment 1 Bottom view of the patch in the first embodiment Front view of the patch in the first embodiment Left side view of the patch in the first embodiment Sectional drawing in the XX line of FIG. The figure which shows the state which forms a finger hook in the patch in Embodiment 1 The figure which shows the state which bent the tongue piece of the cut line of the patch in Embodiment 1 The figure which shows an example of the sticking operation | work to the skin affected part of the patch in Embodiment 1 Plan view of the patch in the second embodiment Plan view of patch in embodiment 3 Plan view of patch in embodiment 4 Top view of patch in embodiment 5 Plan view of patch in embodiment 6 Plan view of the patch in the seventh embodiment Plan view of the patch in the eighth embodiment Plan view of patch in embodiment 9 Plan view of the patch in the tenth embodiment Plan view of patch in embodiment 11 Plan view of patch in embodiment 12 Plan view of patch in embodiment 13 Plan view of patch in embodiment 14 Plan view of the patch in the fifteenth embodiment Plan view of patch in embodiment 16 Plan view of patch in embodiment 17 Plan view of patch in embodiment 18 Plan view of patch according to embodiment 19 Plan view of patch in embodiment 20 Plan view of patch in embodiment 21 Plan view of patch in embodiment 22 Plan view of patch in embodiment 23 Plan view of patch according to embodiment 24 Plan view of patch in embodiment 25 Plan view of patch in embodiment 26 Plan view of patch in embodiment 27 Plan view of patch in embodiment 28 Plan view of patch in embodiment 29 Plan view of patch in embodiment 30 Plan view of patch in embodiment 31

Explanation of symbols

1, 1a, 1b, 1c, 1d, 1e, 1f, 1g, 1h, 1i, 1j, 1k, 1l, 1m, 1n, 1o, 1p, 1q, 1r, 1s, 1t, 1u, 1v, 1w, 1x, 1y, 1z, 1α, 1β, 1γ, 1δ Patch 2 Support 3 Adhesive layer 4 Release sheet 5, 6 Edge 7, 7e, 7g, 7γ Cut 8, 8b, 8d, 8e, 8f, 8h, 8i, 8j , 8k, 8l, 8m, 8n, 8o, 8p, 8q, 8s, 8t, 8u, 8v, 8w, 8y score line 9, 9b, 9d, 9e, 9f, 9h, 9i, 9j, 9k, 9l, 9m, 9n, 9r, 9s, 9t, 9u, 9v, 9y Main cut portions 10, 10b, 10d, 10e, 10r, 10s, 10t, 10u, 10y Cut-side extending portions 11, 11b, 11d, 11s Parallel cut portions 12, 12b, 12d, 12e, 1 f, 12h, 12i, 12j, 12l, 12m, 12n, 12r Tongue piece 13, 13o, 13p, 13q, 13w Edge part 14 Finger hole 15 Skin affected part 16, 16β, 16δ Folding line 17, 17k, 17n Folding line 18, 18h, 18l, 18r, 18t, 18u, 18v Outer extending portion 19 Folding line 20, 20x First cut 21, 20x Second cut 22 Band part

Claims (9)

A support, an adhesive layer laminated on one surface of the support, a release sheet that is releasably attached to the adhesive layer and has a cut formed from one edge to the other edge opposite to the adhesive sheet; A patch comprising
The patch, wherein the release sheet includes a finger hooking hole for hanging a part of a finger formed by a cut line on the left and right of the cut. A support, an adhesive layer laminated on one surface of the support, a release sheet attached to the adhesive layer in a peelable manner, and a distance from one edge of the release sheet to the other edge opposite to the release sheet And a second cut extending from one edge of the release sheet to the other edge opposite to the first cut and extending from the first cut. ,
The patch, wherein the release sheet includes a finger hooking hole for hanging a part of a finger formed by a cut line on the left side of the first cut and the right side of the second cut.   The incision line is formed with a gap between the cut, the first cut, and the second cut, and from the main cut to the cut, the first cut, and the second cut. The patch according to claim 1 or 2, further comprising a cut-side extending portion extending.   The sticking line according to claim 3, wherein the cut line includes an outer extending portion that extends from the main cut portion to the opposite side of the cut, the first cut, and the second cut. Agent.   The said cut line is provided with the parallel cut part extended in the substantially parallel direction with the said cut, said 1st cut, and said 2nd cut from the terminal of the said cut side extension part. Or the patch according to 4.   The patch according to any one of claims 3 to 5, wherein the release sheet is provided with a fold line extending in the cut side extending portion or the parallel cut portion.   The patch according to any one of claims 1 to 6, wherein the adhesive layer contains a transdermally absorbable drug.   The patch according to claim 7, wherein the transdermally absorbable drug is an anti-inflammatory agent.   The patch according to claim 7, wherein the transdermally absorbable drug is a therapeutic agent for dementia.

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