JP2008546424A - 修飾ポリヌクレオチドを作製する方法および配列決定する方法 - Google Patents

修飾ポリヌクレオチドを作製する方法および配列決定する方法 Download PDF

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JP2008546424A
JP2008546424A JP2008519600A JP2008519600A JP2008546424A JP 2008546424 A JP2008546424 A JP 2008546424A JP 2008519600 A JP2008519600 A JP 2008519600A JP 2008519600 A JP2008519600 A JP 2008519600A JP 2008546424 A JP2008546424 A JP 2008546424A
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primer
tag
modified
polynucleotide sequence
phosphorothiolate
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Japanese (ja)
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ダグラス アール． スミス，
ケビン ジェイ． マッカーナン，
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アジェンコート パーソナル ジェノミクス コーポレイション
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
JP2008519600A 2005-06-28 2006-06-28 修飾ポリヌクレオチドを作製する方法および配列決定する方法 Pending JP2008546424A (ja)

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US69478305P 2005-06-28 2005-06-28
PCT/US2006/025529 WO2007002890A2 (en) 2005-06-28 2006-06-28 Methods of producing and sequencing modified polynucleotides

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JP2008546424A true JP2008546424A (ja) 2008-12-25

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JP2011087807A Pending JP2011155986A (ja) 2005-06-28 2011-04-11 修飾ポリヌクレオチドを作製する方法および配列決定する方法

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US (4) US7645866B2 (US08058030-20111115-C00011.png)
EP (1) EP1907584A2 (US08058030-20111115-C00011.png)
JP (2) JP2008546424A (US08058030-20111115-C00011.png)
WO (1) WO2007002890A2 (US08058030-20111115-C00011.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019504837A (ja) * 2016-01-29 2019-02-21 ユニヴェルシテット ワルシャウスキ ５’−ホスホロチオラート ｍＲＮＡ ５’−末端（キャップ）類似体、それを含むｍＲＮＡ、それらを得る方法およびそれらの使用方法

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
EP1907584A2 (en) * 2005-06-28 2008-04-09 Agencourt Personal Genomics Corporation Methods of producing and sequencing modified polynucleotides
WO2007111937A1 (en) 2006-03-23 2007-10-04 Applera Corporation Directed enrichment of genomic dna for high-throughput sequencing
US8889348B2 (en) 2006-06-07 2014-11-18 The Trustees Of Columbia University In The City Of New York DNA sequencing by nanopore using modified nucleotides
US20080131937A1 (en) * 2006-06-22 2008-06-05 Applera Corporation Conversion of Target Specific Amplification to Universal Sequencing
EP3031919B1 (en) * 2007-07-31 2018-09-19 BASF Enzymes LLC Tailored multi-site combinational assembly
WO2009067632A1 (en) * 2007-11-20 2009-05-28 Applied Biosystems Inc. Method of sequencing nucleic acids using elaborated nucleotide phosphorothiolate compounds
WO2010014820A2 (en) * 2008-07-30 2010-02-04 Life Technologies Corporation Particles for use in supported nucleic acid ligation and detection sequencing
US10036063B2 (en) 2009-07-24 2018-07-31 Illumina, Inc. Method for sequencing a polynucleotide template
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
US8845880B2 (en) 2010-12-22 2014-09-30 Genia Technologies, Inc. Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
US8962242B2 (en) 2011-01-24 2015-02-24 Genia Technologies, Inc. System for detecting electrical properties of a molecular complex
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
JP2015525077A (ja) 2012-06-15 2015-09-03 ジェニア・テクノロジーズ・インコーポレイテッド チップの構成および高精度な核酸配列決定
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
WO2014126937A1 (en) * 2013-02-14 2014-08-21 The Board Of Trustees Of The Leland Stanford Junior University Suspension arrays and multiplexed assays based thereon
WO2014134338A1 (en) * 2013-03-01 2014-09-04 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Oligonucleotide functionalized quantum dots
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
EP3640349A3 (en) 2013-10-23 2020-07-29 Roche Sequencing Solutions, Inc. High speed molecular sensing with nanopores
US9322062B2 (en) 2013-10-23 2016-04-26 Genia Technologies, Inc. Process for biosensor well formation
JP6573899B2 (ja) 2013-11-17 2019-09-11 クアンタム−エスアイ インコーポレイテッドＱｕａｎｔｕｍ−Ｓｉ Ｉｎｃｏｒｐｏｒａｔｅｄ 分子をプローブし、検出し、及び分析するための、外部光源を備えた集積デバイス
WO2015167972A1 (en) * 2014-04-28 2015-11-05 Tsavachidou Dimitra Methods for nucleic acid base determination
CN106796176B (zh) 2014-08-08 2021-02-05 宽腾矽公司 用于对分子进行探测、检测和分析的带外部光源的集成装置
KR102384909B1 (ko) 2014-08-08 2022-04-11 퀀텀-에스아이 인코포레이티드 수신된 광자들의 시간 비닝을 위한 집적 디바이스
JP6812341B2 (ja) 2014-08-08 2021-01-13 クアンタム−エスアイ インコーポレイテッドＱｕａｎｔｕｍ−Ｓｉ Ｉｎｃｏｒｐｏｒａｔｅｄ 分子の探索、検出及び解析のための光学システム及びアッセイチップ
US10303666B2 (en) 2015-03-09 2019-05-28 International Business Machines Corporation File transfer system using file backup times
US10174363B2 (en) 2015-05-20 2019-01-08 Quantum-Si Incorporated Methods for nucleic acid sequencing
AU2017219894B2 (en) 2016-02-17 2021-12-09 Tesseract Health, Inc. Sensor and device for lifetime imaging and detection applications
BR112019012540A2 (pt) 2016-12-22 2019-11-12 Quantum-Si Incorporated fotodetector integrado com pixel de acondicionamento direto
WO2019246328A1 (en) 2018-06-22 2019-12-26 Quantum-Si Incorporated Integrated photodetector with charge storage bin of varied detection time

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002525129A (ja) * 1998-10-01 2002-08-13 バリアジェニックス，インク． ポリヌクレオチドを分析するための方法
WO2002090522A2 (en) * 2001-05-10 2002-11-14 San Diego State University Foundation Use of phosphorothiolate polynucleotides in ligating nucleic acids

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
CA2077135A1 (en) * 1991-08-30 1993-03-01 Joh-E Ikeda A method of dna amplification
GB9208733D0 (en) 1992-04-22 1992-06-10 Medical Res Council Dna sequencing method
US5705628A (en) * 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
WO1998053300A2 (en) * 1997-05-23 1998-11-26 Lynx Therapeutics, Inc. System and apparaus for sequential processing of analytes
CZ293215B6 (cs) * 1996-08-06 2004-03-17 F. Hoffmann-La Roche Ag Rekombinantní tepelně stálá DNA polymeráza, způsob její přípravy a prostředek, který ji obsahuje
US6124092A (en) 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
US6117634A (en) 1997-03-05 2000-09-12 The Reagents Of The University Of Michigan Nucleic acid sequencing and mapping
US6534262B1 (en) * 1998-05-14 2003-03-18 Whitehead Institute For Biomedical Research Solid phase technique for selectively isolating nucleic acids
US6500650B1 (en) 1998-10-01 2002-12-31 Variagenics, Inc. Method for identifying polymorphisms
GB9901475D0 (en) * 1999-01-22 1999-03-17 Pyrosequencing Ab A method of DNA sequencing
US6329178B1 (en) * 2000-01-14 2001-12-11 University Of Washington DNA polymerase mutant having one or more mutations in the active site
AU2002239826A1 (en) * 2001-01-09 2002-07-24 Whitehead Institute For Biomedical Research Methods and reagents for the isolation of nucleic acids
US6887690B2 (en) * 2001-06-22 2005-05-03 Pe Corporation Dye-labeled ribonucleotide triphosphates
US6942974B2 (en) 2002-03-08 2005-09-13 Applera Corporation Selective elution of immobilized multiplexed primer extension products
US6858393B1 (en) * 2002-03-13 2005-02-22 Stratagene California Chain terminators for DNA synthesis
EP1907584A2 (en) * 2005-06-28 2008-04-09 Agencourt Personal Genomics Corporation Methods of producing and sequencing modified polynucleotides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002525129A (ja) * 1998-10-01 2002-08-13 バリアジェニックス，インク． ポリヌクレオチドを分析するための方法
WO2002090522A2 (en) * 2001-05-10 2002-11-14 San Diego State University Foundation Use of phosphorothiolate polynucleotides in ligating nucleic acids

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019504837A (ja) * 2016-01-29 2019-02-21 ユニヴェルシテット ワルシャウスキ ５’−ホスホロチオラート ｍＲＮＡ ５’−末端（キャップ）類似体、それを含むｍＲＮＡ、それらを得る方法およびそれらの使用方法
JP7144050B2 (ja) 2016-01-29 2022-09-29 ユニヴェルシテット ワルシャウスキ ５’－ホスホロチオラート ｍＲＮＡ ５’－末端（キャップ）類似体、それを含むｍＲＮＡ、それらを得る方法およびそれらの使用方法

Also Published As

Publication number Publication date
JP2011155986A (ja) 2011-08-18
US20070026438A1 (en) 2007-02-01
US20100298551A1 (en) 2010-11-25
US7645866B2 (en) 2010-01-12
US20100285461A1 (en) 2010-11-11
US8058030B2 (en) 2011-11-15
US20100297628A1 (en) 2010-11-25
WO2007002890A3 (en) 2007-06-28
WO2007002890A2 (en) 2007-01-04
EP1907584A2 (en) 2008-04-09

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