JP2008264632A - Degassing filtering device - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a degassing filtering device capable of preventing breakage of a container and enhancing the efficiency of a degassing filtering work. <P>SOLUTION: The degassing filtering device, which obtains filtrate by applying degassing filtering to a solvent, is provided with: a first container storing the solvent; a second container storing the filtrate; and a connection mechanism connecting the first and second containers. The first container and connection mechanism are formed of an acid resistant material. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a degassing filtration device for producing a filtrate by subjecting a solvent to degassing filtration.

  In the quality inspection of beer and the development of new beer, an analysis process for analyzing trace components contained in beer is indispensable. In such an analysis process, a high performance liquid chromatography instrument has been conventionally used. In addition, when using (operating) a high performance liquid chromatography instrument, it is necessary to introduce a solution obtained by degassing and filtering the adjusted solvent (that is, a filtrate that has undergone degassing filtration) to the high performance liquid chromatography instrument. It becomes.

  In the degassing filtration operation, generally, as shown in FIG. 5, a receiving container 1100 for storing a solvent to be degassed filtered and a filtrate storage container for storing a filtrate that is a solvent subjected to degassing filtration. The deaeration filtration apparatus 1000 which has 1200 and the connection tool 1300 which connects a receiving container 1100 and a filtrate storage container is used. When using the degassing filtration apparatus 1000, the connection portion 1310 of the connection device 1300 shown in FIG. 6 is connected (slid) to the connection portion 1210 of the filtrate storage container 1200, and the receiving container 1100 is mounted on the connection device 1300. Put. Here, FIG. 5 is a schematic perspective view showing a configuration of a conventional degassing filtration apparatus 1000. FIG. 6 is a schematic front view showing a filtrate storage container 1200 and a connection device 1300 of a conventional degassing filtration apparatus 1000.

Heretofore, several techniques have been proposed as techniques related to high performance liquid chromatography equipment (see Patent Documents 1 and 2).
JP-A-7-260761 Japanese Patent Laid-Open No. 10-185892

  However, in the conventional degassing filtration device, a force is easily applied to the connecting portion between the receiving vessel and the filtrate storage container (the connecting portion of the connecting device and the connecting portion of the filtrate storage vessel), and the receiving vessel, the connecting device, and the filtrate Since all the storage containers were made of glass, the connecting device and the filtrate storage container were often damaged. Furthermore, in the filtration and deaeration work, since the inside of the receiving container becomes a negative pressure, there is a risk that the receiving container is damaged.

  Moreover, since the unit of use of the filtrate in the high performance liquid chromatography instrument is 3 liters, it is preferable to produce 3 liters of filtrate in one degassing filtration operation. However, since the maximum capacity of the filtrate storage container in the conventional degassing filtration apparatus is 1 liter, the produced filtrate must be transferred to a container having a capacity of 3 liters and introduced into a high performance liquid chromatography instrument. Therefore, at least three transfer operations are required, which is very laborious. Further, since the capacity of the receiving container is smaller than the capacity of the filtrate storage container, the degassing filtration work must be performed in multiple times (ie, while adding the solvent), which requires a long time. It was.

  Patent Document 1 discloses a technique for replenishing and degassing a solvent without interrupting the analysis operation, and describes that it is preferable to appropriately select the material of the container according to the stored liquid. However, no consideration is given to breakage of a portion where a force such as a connecting portion between the receiving container and the filtrate storage container is easily applied. Patent Document 2 discloses a technique capable of continuously mixing, stirring, and degassing a solvent, but does not particularly describe the material of the container. Patent Documents 1 and 2 have a description that it is possible to directly introduce a filtrate by directly connecting a degassing filtration apparatus to a liquid high-speed chromatography instrument. However, when the filtrate is continuously introduced, the old filtrate (solvent) and the new filtrate (solvent) are mixed, which is not preferable for the actual analysis process (in other words, the lot is regularly added). Is preferable).

  Therefore, an object of the present invention is to provide a degassing filtration device that can prevent breakage of the container and achieve efficiency of degassing filtration work.

  In order to achieve the above object, a degassing filtration apparatus according to one aspect of the present invention is a degassing filtration apparatus for producing a filtrate by subjecting a solvent to degassing filtration, and a first container for storing the solvent. And a second container for storing the filtrate, and a connection mechanism for connecting the first container and the second container, wherein the first container and the connection mechanism have acid resistance. It is composed of a material. According to such a degassing filtration apparatus, the first container and the connection mechanism are made of an acid-resistant resin material, so that the first container, the second container, and the connection mechanism can be prevented from being damaged. The first container and the second container have a capacity of at least 3 liters. Thereby, at least 3 liters of filtrate can be collectively generated and stored in the second container without adding solvent to the first container. Examples of the acid-resistant material include polypropylene, polymethacryl, and polyethylene terephthalate. Here, polypropylene is preferable. It further has a cover for storing the first container and the second container. Thereby, even when the first container and / or the second container is damaged, it is possible to prevent the fragments, the solvent, and the like of the first container and / or the second container from being scattered outside. The cover may be made of a material having impact resistance and chemical resistance if not as much as the above-mentioned solvent container, but here, the cover is preferably made of an acrylic resin. The connection mechanism has a suction hole for sucking the filtrate and guiding it to a component analyzer. This makes it possible to deliver the filtrate stored in the second container to a component analyzer that uses the filtrate.

  Further objects and other features of the present invention will become apparent from the preferred embodiments described below with reference to the accompanying drawings.

  ADVANTAGE OF THE INVENTION According to this invention, while preventing damage to a container, the deaeration filtration apparatus which can achieve the efficiency improvement of a deaeration filtration operation | work can be provided.

  DESCRIPTION OF EXEMPLARY EMBODIMENTS Hereinafter, preferred embodiments of the invention will be described with reference to the accompanying drawings. In addition, in each figure, the same reference number is attached | subjected about the same member and the overlapping description is abbreviate | omitted.

  FIG. 1 is a schematic front view showing a configuration of a degassing filtration device 1 as one aspect of the present invention. The degassing filtration device 1 is a device that generates a filtrate by subjecting a solvent to degassing filtration, and is suitable, for example, as a device that generates a filtrate to be introduced into a high performance liquid chromatography instrument. As shown in FIG. 1, the degassing filtration device 1 includes a receiving container (first container) 10, a filtrate storage container 20 (second container), a connection mechanism 30, a stirrer 40, and a cover 50. Have.

  The receiving container 10 is a container for storing a solvent to be degassed and has a capacity of at least 3 liters. In other words, the receiving container 10 can store at least 3 liters of solvent without adding solvent, and enables at least 3 liters of filtrate to be collectively generated. Therefore, the work time required for the deaeration filtration work can be made shorter than before (that is, the deaeration filtration work can be performed in a short time), which contributes to the efficiency of the deaeration filtration work. The receiving container 10 has, for example, a substantially cylindrical shape, and as shown in FIG. 2, functions as an inlet for receiving the stored solvent into the container 10 and for discharging the stored solvent from the container 10. It has the opening part 12 which has a function as a payout opening. Further, the receiving container 10 is connected to a connection mechanism 30 to be described later via the connection portion 14. Here, FIG. 2 is a schematic sectional view of the receiving container 10.

  The receiving container 10 is made of a material having resistance to a stored solvent, specifically, a material having acid resistance. Thereby, the intensity | strength of the receiving container 10 can be improved rather than the case where the receiving container 10 is comprised with glass. Accordingly, it is possible to prevent (reduce) damage to the receiving container 10 when the receiving container 10 is connected to the connection mechanism 30 or when force is applied to the receiving container 10 (particularly, the connection portion 14 with the connection mechanism 30). . In addition, examples of the acid-resistant material include polypropylene, polymethacryl, polyethylene terephthalate, and the like. In this embodiment, polypropylene is preferable. Since the receiving container 10 made of polypropylene also has flexibility, even if the internal pressure of the receiving container 10 becomes a negative pressure during the filtration deaeration operation, the receiving container 10 can be prevented from being damaged.

  The filtrate storage container 20 is a container for storing the filtrate that has been subjected to deaeration filtration, and is placed on the stirrer 40. The filtrate storage container 20 may store the filtrate supplied (injected) through a degassing filtration unit that performs degassing filtration on the solvent stored in the receiving container 10, or the solvent supplied from the receiving container 10. The filtrate produced by performing deaeration filtration in the filtrate storage container 20 may be stored. In this embodiment, the filtrate storage container 20 is embodied as a container for storing the moving layer of the high performance liquid chromatography instrument. The filtrate storage container 20 is made of glass in the present embodiment, but may be made of polypropylene as in the case of the receiving container 10.

  The filtrate storage container 20 has a capacity of at least 3 liters. In other words, the filtrate storage container 20 can store at least 3 liters of filtrate. Therefore, for example, when a 3 liter filtrate is required as in a high performance liquid chromatography instrument, it is not necessary to transfer the produced filtrate to another container (for example, a container having a capacity of 3 liters). The efficiency of deaeration work can be improved. Further, the filtrate storage container 20 is connected to a connection mechanism 30 to be described later via the connection portion 24.

  In the present embodiment, the filtrate storage container 20 contains a stirrer (not shown). By moving the stirring bar, the filtrate stored in the filtrate storage container 20 can be stirred.

  The connection mechanism 30 has a function of connecting the receiving container 10 and the filtrate storage container 20, performing degassing filtration on the solvent stored in the receiving container 10, and introducing the solvent into the filtrate storage container 20. As shown in FIGS. 3 and 4, the connection mechanism 30 includes a receiving-side connecting part 32 that connects to the connecting part 14 of the receiving container 10 and a filtrate-side connecting part 34 that connects to the connecting part 24 of the filtrate storage container 20. Have. In this embodiment, the connection part 14 and the receiving side connection part 32 of the receiving container 10 are connected by a seal | sticker, and the connection part 24 and the filtrate side connection part 34 of the filtrate storage container 20 are connected by screw joining. The degassing filtration device 1 of the present embodiment does not limit the connection form between the receiving container 10 and the connection mechanism 30 and the connection form between the filtrate storage container 20 and the connection mechanism. Such a connection configuration in which the connecting portions are rubbed together is not preferable because force is easily applied to the connecting portions. Thereby, it becomes possible to prevent the filtrate storage container 20 from being damaged. Here, FIG. 3 is a schematic front view of the connection mechanism 30. FIG. 4 is a schematic cross-sectional view of the connection mechanism 30.

  The connection mechanism 30 is formed with a flow path 36 for introducing the solvent stored in the receiving container 10 into the filtrate storage container 20. In a state where the receiving container 10 and the filtrate storage container 20 are connected via the connection mechanism 30, the opening 12 of the receiving container 10, the flow path 36 of the connection mechanism 30, and the inlet of the filtrate storage container 20 communicate with each other. In addition, a suction port 38 for sucking the filtrate stored in the filtrate storage container 20 is branched from the flow path 36 in the connection mechanism 30. A suction device is connected to the suction port 38. By driving the suction device, the filtrate stored in the filtrate storage container 20 is sucked, and the device in the subsequent process (that is, stored in the filtrate storage container 20). It can be handed over to the component analyzer using the filtrate.

  In addition, the connection mechanism 30 includes a filtering unit 39 that filters the solvent stored in the receiving container 10. In the present embodiment, the filtration unit 39 is configured by a filter and is disposed in the receiving side connection unit 32. The solvent stored in the receiving container 10 is filtered by passing through a filter as the filtering unit 39. The filtration unit 39 can be a metal mesh filter, a membrane filter, or the like.

  The connection mechanism 30 is made of a material having resistance to a solvent (filtrate), specifically, an acid-resistant resin material, like the receiving container 10. Thereby, the intensity | strength of the connection mechanism 30 can be improved rather than the conventional connection instrument comprised with glass. Accordingly, the connection mechanism 30 is prevented from being damaged (reduced) when connecting to the receiving container 10 or the filtrate storage container 20 or when a force is applied to the connection mechanism 30 (particularly, the receiving side connection part 32 and the filtrate side connection part 34). can do.

  The stirrer 40 has a function of placing the filtrate storage container 20 and rotating the filtrate storage container 20. The stirrer 40 accommodated in the filtrate storage container 20 can be moved by rotating the filtrate storage container 20 by the stirrer 40. The stirrer 40 can be applied with any configuration known in the art, and a detailed description of the structure and operation is omitted here.

  The cover 50 accommodates at least the receiving container 10 and the filtrate storage container 20, and in this embodiment, accommodates the receiving container 10, the filtrate storage container 20, the connection mechanism 30, and the stirrer 40. Thereby, even when the receiving container 10 and / or the filtrate storage container 20 are damaged, the debris of the receiving container 10 and / or the filtrate storage container 20, the solvent stored in the receiving container 10 and the filtrate storage container 20 are stored. It is possible to prevent the filtrate from being scattered outside. In addition, it is preferable to comprise the cover 50 with an acrylic resin so that degassing filtration work (the receiving container 10, the filtrate storage container 20, etc.) can be visually observed. However, the material constituting the cover 50 is not limited to acrylic resin, and may be any material having impact resistance and chemical resistance.

  In using the degassing filtration device 1, first, the receiving container 10 storing the solvent and the filtrate storage container 20 are connected. Specifically, the connection part 14 of the receiving container 10 and the receiving side connection part 32 of the connection mechanism 30 are connected, and the connection part 24 of the filtrate storage container 20 and the filtrate side connection part 34 of the connection mechanism 30 are connected. At this time, the receiving container 10 and the connection mechanism 30 are made of an acid-resistant material (polypropylene), and the connection mechanism 30 and the filtrate storage container 20 are connected by screw connection. Damage to the storage container 20 and the connection mechanism 30 can be prevented.

  Next, the receiving container 10 and the filtrate storage container 20 connected via the connection mechanism 30 are housed in the cover 50, and a suction device is connected to the suction port 38 of the connection mechanism 30. A stirrer 40 is disposed inside the cover 50, and the filtrate storage container 20 is placed on the stirrer 40.

  Next, the solvent stored in the receiving container 10 is filtered through the filtering unit 39 to generate a filtrate, and the filtrate is stored in the filtrate storage container 20. At this time, since the receiving container 10 has a capacity of at least 3 liters, a filtrate of at least 3 liters can be generated without adding a solvent to the receiving container 10. Similarly, since the filtrate storage container 20 has a capacity of at least 3 liters, the produced filtrate can be stored without transferring the filtrate to another container. Thereby, the deaeration filtration operation can be easily performed in a short time.

  The filtrate stored in the filtrate storage container 20 is sucked by a suction device (not shown) and delivered to a subsequent device through a suction port 38 of the connection mechanism 30. The filtrate stored in the filtrate storage container 20 may be stirred by the stirrer 40 and the stirring bar.

  Thus, according to the deaeration filtration device 1, it is possible to prevent breakage of the containers (the receiving container 10 and the filtrate storage container 20) and the breakage of the connection mechanism 30, and achieve efficiency of the deaeration filtration work. .

  The preferred embodiments of the present invention have been described above, but the present invention is not limited to these embodiments, and various modifications and changes can be made within the scope of the gist.

It is a schematic front view which shows the structure of the deaeration filtration apparatus as one side surface of this invention. It is a schematic sectional drawing of the receiving container in the deaeration filtration apparatus shown in FIG. It is a schematic front view of the connection mechanism in the deaeration filtration apparatus shown in FIG. It is a schematic sectional drawing of the connection mechanism in the deaeration filtration apparatus shown in FIG. It is a schematic perspective view which shows the structure of the conventional deaeration filtration apparatus. It is a schematic front view which shows the filtrate storage container and connection instrument of the conventional deaeration filtration apparatus.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Deaeration filtration apparatus 10 Receiving container 12 Opening part 14 Connection part 20 Filtrate storage container 24 Connection part 30 Connection mechanism 32 Receiving side connection part 34 Filtrate side connection part 36 Flow path 38 Suction port 39 Filtration part 40 Stirrer 50 Cover

Claims (6)

A degassing filtration device for producing a filtrate by subjecting a solvent to degassing filtration,
A first container for storing the solvent;
A second container for storing the filtrate;
A connection mechanism for connecting the first container and the second container;
The first container and the connection mechanism are made of an acid-resistant material, and a degassing filtration device.   The degassing filtration apparatus according to claim 1, wherein the first container and the second container have a capacity of at least 3 liters.   The degassing filtration apparatus according to claim 1, wherein the acid-resistant material is polypropylene.   The degassing filtration apparatus according to claim 1, further comprising a cover for housing the first container and the second container.   The degassing filtration apparatus according to claim 4, wherein the cover is made of an acrylic resin.   The degassing filtration device according to claim 1, wherein the connection mechanism has a suction port for sucking the filtrate and guiding the filtrate to a component analyzer.

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