JP2008220541A - Multi chamber container - Google Patents

Multi chamber container Download PDF

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JP2008220541A
JP2008220541A JP2007061213A JP2007061213A JP2008220541A JP 2008220541 A JP2008220541 A JP 2008220541A JP 2007061213 A JP2007061213 A JP 2007061213A JP 2007061213 A JP2007061213 A JP 2007061213A JP 2008220541 A JP2008220541 A JP 2008220541A
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bag
drug
medicine
discharge port
discharge
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JP2008220541A5 (en
JP4924936B2 (en
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Yasuhiro Muramatsu
康宏 村松
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Ajinomoto Co Inc
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Ajinomoto Co Inc
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Abstract

<P>PROBLEM TO BE SOLVED: To remove creases at a portion in the root part of a liquid medicine bag despite of attaching a medicine discharge prevention implement for preventing a puncture under a non-communicated state in a multi chamber container. <P>SOLUTION: The medicine discharge prevention implement 28 includes upper/lower half bodies 28A and 28B clamped by an outlet in the liquid medicine bag, and a restriction member uniting and restricting the upper/lower half bodies 28A and 28B under elasticity, and prevents the puncture when the medicine discharge prevention implement 28 is attached to the liquid medicine bag. The medicine discharge prevention implement includes a pair of flaps 30 and 32 abutting on liquid medicine bag opposite surfaces, when abutting on the liquid solution bag opposite surfaces, the flaps 30 and 32 are wide opened in response to the swelling of the liquid medicine bag in the communication of the liquid medicine bag to release the restriction of the upper/lower half bodies 28A and 28B by the restriction members, and the medicine discharge prevention implement 28 is separated from the liquid medicine bag to allow the puncture. The opposite bases of the flaps 30 and 32 form recessed surfaces 30A and 30B and, even if creases are formed in the liquid medicine bag root part 10' when attaching the medicine discharge prevention implement 28 thereto, the creases can be smoothed and removed. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

この発明は排出口に薬剤排出阻止具を備えることで未開通時の穿刺を阻止するようにした複室容器に関するものである。   The present invention relates to a multi-chamber container that is provided with a medicine discharge prevention tool at a discharge port to prevent puncture when not opened.

合成樹脂フィルムよりなる薬液バッグの外周にプラスチック成型品としての排出口を装着し、かつ薬液バッグを構成する合成樹脂フィルム上下層を剥離可能に溶着してなる弱シール部により薬液バッグ内部を複数の隔室に構成し、輸液時に弱シール部を開通させ、隔室間の薬剤を混合して排出口より排出させるようにした複室容器がある。この種の複室容器においては輸液前の弱シール部の開通操作は必須であり、弱シール部未開通で輸液すると一液のみの輸液となり誤作業となる。そこで、このような誤作業を未然に防止するため、排出口に薬剤排出阻止具を装着したものが公知である(特許文献1)。この技術では、薬剤排出阻止具は筒状体を半割りにして構成され、半割筒状体を排出口を挟んで合体させることにより排出口は被覆され、穿刺用のゴム栓に対するアクセスが阻止され、薬液バッグ未開通で一液のみで輸液が行われてしまうという誤作業を防止することができる。半割筒状体からは一対のフラップが延出され、フラップは排出口付近において薬剤バッグを構成する合成樹脂フィルム外面より弾性力下で挟着保持する。弱シール部の剥離開通は薬液バッグにおける薬液の部位を加圧することにより行われる。即ち、薬液バッグの加圧により薬液バッグは膨れ、弱シール部に剥離力が加わり、弱シールは開通される。弱シール開通時の薬液バッグ内に惹起される衝撃的な薬液の流れにより排出口の取り付け部位において薬液バッグは急拡開され、フラップは拡開付勢され、弾性拘束部材による一対の拘束状態は解除され、薬剤排出阻止具は薬液バッグから離脱せしめられる。そのため、排出口は露出され、輸液セットがアクセス可能となり、穿刺により混合薬液の輸液が可能となる。   A discharge port as a plastic molded product is attached to the outer periphery of the chemical solution bag made of a synthetic resin film, and the inside of the chemical solution bag is divided into a plurality of portions by a weak seal portion formed by releasably welding the upper and lower layers of the synthetic resin film constituting the chemical solution bag. There is a multi-chamber container which is configured in a compartment and opens a weak seal portion at the time of infusion, and mixes the medicine between the compartments and discharges them from the outlet. In this type of multi-chamber container, the opening operation of the weak seal part before infusion is essential, and if the infusion is performed without the weak seal part being opened, only one liquid will be infused, resulting in an erroneous operation. Therefore, in order to prevent such an erroneous operation, a device in which a medicine discharge prevention tool is attached to the discharge port is known (Patent Document 1). In this technology, the medicine discharge prevention device is configured with a cylindrical body divided in half, and the discharge opening is covered by combining the half cylindrical body with the discharge opening interposed therebetween, and access to the rubber stopper for puncture is blocked Thus, it is possible to prevent an erroneous operation that the infusion is performed with only one solution when the chemical solution bag is not opened. A pair of flaps extend from the half cylinder, and the flaps are sandwiched and held under the elastic force from the outer surface of the synthetic resin film constituting the drug bag in the vicinity of the discharge port. The weak seal portion is peeled and opened by pressurizing the portion of the chemical solution in the chemical solution bag. That is, the chemical solution bag is expanded by pressurization of the chemical solution bag, a peeling force is applied to the weak seal portion, and the weak seal is opened. The chemical bag is rapidly expanded at the attachment site of the discharge port by the shocking flow of the chemical solution induced in the chemical bag when the weak seal is opened, the flap is expanded and biased, and the pair of restrained states by the elastic restraining member is The drug discharge prevention device is released from the drug solution bag. Therefore, the discharge port is exposed, the infusion set can be accessed, and the mixed drug solution can be infused by puncture.

その他、本発明に関連する先行技術として特許文献2及び3がある。
WO2005/097039号公報 実用新案登録公報第2600011号公報 実開昭58−161814号公報
In addition, there are Patent Documents 2 and 3 as prior arts related to the present invention.
WO2005 / 097039 Utility Model Registration Gazette No. 2600011 Japanese Utility Model Publication No. 58-161814

薬剤排出阻止具の装着は薬剤バッグの夫々の隔室への薬液の収納密封を行い、薬剤バッグ外周部に排出口を装着及びシールを完了してから行われる。即ち、薬剤排出阻止具を構成する一対の半割筒状体は排出口を上下から挟着するように配置され、夫々の半割筒状体から延設されるフラップが薬剤バッグを上下から接触するように配置し、弾性拘束部材により半割筒状体の合体状態及び合成樹脂フィルム対向面に対するフラップの接触状態を保持するようにしている。そして、フラップは平坦な底面をなしており、そのため、フラップは実質的全面において合成樹脂フィルム対向面に当接せしめられる。薬剤バッグを構成する合成樹脂フィルムは排出口の上下直径部位では排出口の形状に準じて丸みを帯びているが排出口に直近した平坦なフラップ間で押しつぶされるため、排出口に対する付け根の部位で形状が丸から平に急変し皺が発生しやすい。そして、上下のフラップは全面において薬剤バッグ対向面に当接し、かつ上下から弾性力下で薬剤バッグを保持している。したがって、薬剤排出阻止具の装着時に合成樹脂フィルム面に生じた皺は固定されてしまい、輸送中に多数の製品が積み重ねられると、皺の部分に無理な力が加わり、ピンホールなどの欠陥の発生の恐れがあった。   The medicine discharge prevention device is attached after the medicine solution is stored and sealed in each compartment of the medicine bag, and the discharge port is attached to the outer peripheral portion of the medicine bag and sealing is completed. In other words, the pair of halved cylindrical bodies constituting the medicine discharge prevention device are arranged so that the discharge port is sandwiched from above and below, and the flaps extending from the respective half cylindrical bodies contact the medicine bag from above and below. It arrange | positions so that it may hold | maintain and the contact state of the flap with respect to the synthetic resin film opposing surface is hold | maintained by the elastic restraint member. The flap has a flat bottom surface, so that the flap is brought into contact with the synthetic resin film facing surface over substantially the entire surface. The synthetic resin film that forms the drug bag is rounded according to the shape of the discharge port at the upper and lower diameter portions of the discharge port, but is crushed between the flat flaps closest to the discharge port. The shape suddenly changes from round to flat and wrinkles are likely to occur. The upper and lower flaps are in contact with the drug bag facing surface on the entire surface, and hold the drug bag under elastic force from above and below. Therefore, the wrinkles generated on the surface of the synthetic resin film when the medicine discharge prevention device is attached are fixed, and if many products are stacked during transportation, an excessive force is applied to the wrinkles and defects such as pinholes are generated. There was a risk of occurrence.

この発明は以上の問題点に鑑みてなされたものであり、薬剤バッグに対する薬剤排出阻止具の装着時において、薬液バッグの排出口に対する付け根の部位に発生した皺を解消し得るようにすることを目的とする。   The present invention has been made in view of the above-described problems, and is intended to be able to eliminate wrinkles generated at the base portion with respect to the discharge port of the drug solution bag when the drug discharge prevention tool is mounted on the drug bag. Objective.

この発明になる複室容器は、可撓性膜素材にて形成され、弱シールによりその内部が薬剤を個別に収容する複数の隔室に区画された薬剤バッグと、薬剤バッグ外周部に取り付けられ、複数の隔室の一つに開口する排出口と、薬剤バッグの外部に装着され、弱シール未開通時に排出口からの薬剤の排出を阻止する薬剤排出阻止具とを備え、前記薬剤排出阻止具は排出口を挟んで対向され、薬剤バッグの開通時の薬液バッグの膨れ変形に協働せしめる一対の係合部材と、前記係合部材を通常状態において合体拘束し、排出口へのアクセスを阻止するが、係合部材が薬液バッグの膨れ変形と協働時に薬剤排出阻止具を薬液バッグから離脱せしめるべく拘束状態が解除される拘束部材とから成り、前記一対の係合部材の対向面は排出口の実質的延長部位において薬剤バッグと非接触である形状をなす。夫々の係合部材はフラップ等として構成することができ、対向可撓性膜素材面に当接し、薬剤バッグ上下から挟着している。そのため、弱シール剥離による薬剤バッグ開通時におけ薬剤バッグの膨れ変形はフラップにより薬剤排出阻止具に伝達せしめられる。係合部材は排出口の実質的延長部位若しくは幅方向における局部的部位(例えば中央部)において薬剤バッグと非接触、即ち、薬液バッグを実質的にフリーとする形状としている。その手段としてはフラップ等の係合部材における薬剤バッグ対向面を凹面状とすることが可能である。フラップ等の係合部材は排出口の実質的延長部位若しくは幅方向における局部的部位において薬剤バッグをフリーとする形状をなすが、フラップ等の係合部材は両端部等では薬剤バッグと当接しているため、薬剤バッグ開通時の薬剤バッグ拡開と連動させて係合部材を拡開させ、拘束部材による拘束は解除され、薬剤排出阻止具を離脱させ、輸液を開始せしめることができる。   The multi-chamber container according to the present invention is formed of a flexible membrane material, and is attached to a drug bag having a plurality of compartments in which a drug is individually accommodated by a weak seal and an outer peripheral portion of the drug bag. A discharge opening that opens in one of the plurality of compartments; and a drug discharge prevention device that is attached to the outside of the drug bag and blocks discharge of the drug from the discharge port when the weak seal is not opened, The tools are opposed to each other with the discharge port interposed therebetween, and a pair of engaging members that cooperate with the swelling deformation of the drug solution bag when the drug bag is opened, and the engagement members are combined and restrained in a normal state so as to access the discharge port. The engaging member comprises a restraining member that is released from the restraining state so that the medicine discharge preventing tool is released from the chemical solution bag when the engaging member cooperates with the swelling deformation of the chemical solution bag, and the opposing surfaces of the pair of engaging members are Substantial extension of the outlet A shape which is the medical bag in a non-contact at. Each engaging member can be configured as a flap or the like, and is in contact with the opposing flexible membrane material surface and sandwiched from above and below the drug bag. Therefore, when the drug bag is opened due to weak seal peeling, the swelling deformation of the drug bag is transmitted to the drug discharge prevention device by the flap. The engaging member has a shape that is not in contact with the drug bag, that is, the drug solution bag is substantially free at a substantial extension site of the discharge port or a local site in the width direction (for example, the central portion). As the means, it is possible to make the drug bag facing surface of the engaging member such as a flap concave. An engaging member such as a flap is shaped so that the drug bag is free at a substantially extended part of the discharge port or a local part in the width direction, but the engaging member such as a flap is in contact with the drug bag at both ends. Therefore, the engaging member is expanded in conjunction with the expansion of the drug bag when the drug bag is opened, the constraint by the restraining member is released, the drug discharge prevention tool is released, and the infusion can be started.

薬剤排出阻止具の装着は排出口の装着及び薬剤バッグへの薬液の封入後に行われる。即ち、フラップ等の係合部材は上下から薬剤バッグを挟着するように装着せしめられ、弾性式等の拘束手段によりフラップ等の係合部材は合体保持され、薬剤排出阻止具により排出口がカバーされ、穿刺が阻止される。係合部材により上下から薬剤バッグを挟着することで、係合部材との当接部位で薬剤バッグは圧潰されるが、フラップ等の係合部材は底面を凹面とするなどの手段で排出口の延長部位若しくは幅方向における局部的部位では薬液バッグは実質的にフリーである。そのため、薬液バッグに対する薬剤排出阻止具装着時に排出口に対する薬液バッグの付け根の部位で皺が生じても、薬剤排出阻止具に対して薬剤バッグを相対的に変位させ、薬液バッグを緊張させることで皺を引き伸ばすことができる。このように薬剤排出阻止具を薬剤バッグに装着した状態で製品として出荷される。   The medicine discharge prevention device is attached after the discharge port is attached and the liquid medicine is sealed in the medicine bag. That is, the engagement member such as the flap is attached so as to sandwich the drug bag from above and below, the engagement member such as the flap is held together by the elastic type restraining means, and the discharge port is covered by the drug discharge prevention tool. And puncture is prevented. By sandwiching the drug bag from above and below by the engagement member, the drug bag is crushed at the contact portion with the engagement member, but the engagement member such as a flap has a discharge port by means such as a concave bottom surface. The drug solution bag is substantially free at the extended region of the region or the local region in the width direction. Therefore, even if wrinkles occur at the base of the chemical solution bag with respect to the discharge port when the chemical discharge prevention device is attached to the chemical solution bag, the drug bag is displaced relative to the chemical discharge prevention device, and the chemical solution bag is tensioned. You can stretch the cocoon. In this way, the medicine discharge prevention device is shipped as a product with the medicine bag mounted.

フラップの底面を凹面状等とすることにより、排出口の実質的延長部位において薬剤バッグをフリーとしているため、薬剤バッグに対し薬剤排出阻止具を装着後に、排出口に対する薬液バッグの付け根の部位に皺の発生があっても、薬剤排出阻止具と薬剤バッグとの間で適当な緊張力を付与することにより、皺を引き伸ばすことができる。そのため、輸送などの取扱い中に皺を原因とするピンホールの発生の防止を図ることができる。   By making the bottom surface of the flap concave, etc., the drug bag is free at the substantial extension part of the discharge port, so after attaching the drug discharge prevention tool to the drug bag, at the base part of the drug solution bag with respect to the discharge port Even if wrinkles are generated, the wrinkles can be stretched by applying an appropriate tension between the drug discharge prevention device and the drug bag. Therefore, it is possible to prevent the occurrence of pinholes caused by wrinkles during handling such as transportation.

図1〜図7において、医療用混合型薬液封止体は平坦状の薬剤バッグ10と排出口12とから構成される。薬剤バッグ10は厚さ200ミクロンといったポリエチレンムなどの軟弱フィルム(本発明の可撓性素材)を素材とする。ポリエチレンフィルムの外周はその軟化温度より十分高い130℃といった高温にて加圧されることにより形成された強シール部14により封止され、矩形の袋状をなしている。強シール部14には懸垂孔16が穿設され、この懸垂孔16によって薬剤バッグ10を点滴台などに吊り下げ保持し、点滴や透析作業を行うことになる。   1 to 7, the medical mixed-type liquid medicine sealing body includes a flat medicine bag 10 and a discharge port 12. The drug bag 10 is made of a soft film (flexible material of the present invention) such as polyethylene having a thickness of 200 microns. The outer periphery of the polyethylene film is sealed by a strong seal portion 14 formed by being pressed at a high temperature such as 130 ° C., which is sufficiently higher than its softening temperature, and has a rectangular bag shape. A suspension hole 16 is formed in the strong seal portion 14, and the drug bag 10 is suspended and held by the suspension hole 16 on an infusion stand or the like to perform infusion or dialysis.

薬剤バッグ10の長さ方向における中間部位において全幅にわたって弱シール部18が延びており、弱シール部18によって薬剤バッグ10の表裏面が接着され、薬剤バッグ10の内部空洞は第1隔室20と第2隔室22とに区画される。第1隔室20に第1薬液が充填され、第2隔室22に第2薬液が充填される。弱シール部18は薬剤バッグ10を形成するポリエチレンフィルムの表裏面をその軟化温度よりやや高い120℃といった低温にて加圧することにより形成される。そのため、第1隔室20と第2隔室22にそれぞれの薬液を収容した状態で隔室20, 22の部位において薬剤バッグ10における薬液を外側より加圧することにより、強シール部14の溶着状態はそのままに(非剥離状態で)、弱シール部18を破壊・開通せしめ、第1薬液と第2薬液との混合を行うことができる。   The weak seal portion 18 extends over the entire width at an intermediate portion in the length direction of the drug bag 10, and the front and back surfaces of the drug bag 10 are bonded by the weak seal portion 18, and the internal cavity of the drug bag 10 is connected to the first compartment 20. It is partitioned into a second compartment 22. The first compartment 20 is filled with the first chemical solution, and the second compartment 22 is filled with the second chemical solution. The weak seal portion 18 is formed by pressurizing the front and back surfaces of the polyethylene film forming the drug bag 10 at a low temperature such as 120 ° C., which is slightly higher than its softening temperature. Therefore, the strong seal portion 14 is welded by pressurizing the drug solution in the drug bag 10 from the outside in the compartments 20 and 22 with the respective drug solutions stored in the first compartment 20 and the second compartment 22. As is (in a non-peeled state), the weak seal portion 18 can be broken and opened, and the first chemical solution and the second chemical solution can be mixed.

排出口12は、その形態を維持しうる剛性を有した肉厚を有したポリエチレンなどのプラスチック(薬剤バッグ10との密着性を得るため薬剤バッグ10と類似、相溶性のプラスチック素材とする必要がある)の成形品である。図2に示すように、排出口12は上下で開口し、中間がテーパ部12-1をなし、上端にフランジ部12-2(図2)を有した筒状に形成される。フランジ部12-2にはポリエチレン製のキャップ12-3が突当溶着され、キャップ12-3の底面開口部にはゴム製内蓋23が装着される。点滴時には輸液セット(輸液具)の穿刺針24によりゴム製内蓋23を穿刺し、薬剤バッグ10の内部空洞を点滴チューブ26に連通させ、点滴を行うことになる。薬剤バッグ10の表裏面を形成するプラスチックフィルムは排出口12の筒状部を上下より挟みつつ加熱密着され、これにより排出口12に対する薬剤バッグ10の封止が行われている。   The outlet 12 should be made of a plastic material such as polyethylene having rigidity that can maintain its form (such as a plastic material similar to the drug bag 10 in order to obtain adhesion to the drug bag 10). There is a molded product. As shown in FIG. 2, the discharge port 12 is opened in the vertical direction, the middle is a tapered portion 12-1, and is formed in a cylindrical shape having a flange portion 12-2 (FIG. 2) at the upper end. A polyethylene cap 12-3 is abutted and welded to the flange portion 12-2, and a rubber inner lid 23 is attached to the bottom opening of the cap 12-3. At the time of infusion, the rubber inner lid 23 is punctured by the puncture needle 24 of the infusion set (infusion device), and the inside cavity of the medicine bag 10 is communicated with the infusion tube 26 to perform infusion. The plastic film forming the front and back surfaces of the medicine bag 10 is heated and adhered while sandwiching the cylindrical portion of the discharge port 12 from above and below, whereby the drug bag 10 is sealed with respect to the discharge port 12.

図1において、28はこの発明の薬剤排出阻止具を示しており、薬剤排出阻止具28は、薬剤バッグ10の弱シール部18が未開通の状態で、排出口12への輸液セットの穿刺針のアクセスを阻止するためのものである。薬剤排出阻止具28はポリエチレンのようなプラスチックの成形品により形成され、穿刺針による穿刺を防止するに十分な硬度及び/厚みを具備している。薬剤排出阻止具28は筒状体を半割にした形状の第1の半体部分28A(図1)及び第2の部分28B(図2)からなる。第1部分及び第2部分28A, 28Bは薬剤バッグ10を上下から挟着するように配置されており、この実施形態では完全同一形状のものであり、第1の部分及び第2の部分28A, 28Bからは矩形板状の第1フラップ30、第2フラップ32が夫々一体に延出する。第1及び第2のフラップ30, 32がこの発明の係合部材を構成する。図3は上下の半割部分28A, 28Bの合体状態が断面にて示されており、この半割部分28A, 28B間に排出口12を収容するための空洞34が形成される。空洞34は図1及び図2に示すように薬剤バッグ10側(図1及び図2の上端側)では排出口12の外径に対して比較的余裕があるが、薬剤バッグ10から離間側(図1及び図2の下端側)ではフランジ部12-2及びキャップ12-3と略相補的な形状をなしている。そして、図1及び図2に示すように半割部分28A, 28Bは下端側に幾分の拡径部28A-1, 28B-1を備え、拡径部28A-1, 28B-1には図1及び図3に示すように窓部29が形成され、この窓部29には排出口12のフランジ部12-2が延びて来ている。そのため、半割部分28A, 28Bを薬剤バッグ10を上下から挟むように合体させることにより薬剤排出阻止具28を実質的にガタなく排出口12に装着することができる。そして、半割部分28A, 28Bの合体時にその端面28A-2, 28B-2は一枚の円板状の穿刺阻止面を構成する。そのため、図2に示すように輸液セットの穿刺針24によって排出口24のゴム製内蓋23を穿刺しようとしても、薬剤排出阻止具28の穿刺阻止面(28A-2, 28B-2)により穿刺針24がブロックされ、穿刺針24の刺入を行うことはできない。尚、窓部29からは排出口12におけるゴム栓28の上面に設けられるタンパシールの端部を延出せしめることができる。   In FIG. 1, reference numeral 28 denotes a medicine discharge prevention device according to the present invention. The medicine discharge prevention device 28 is a puncture needle of an infusion set to the discharge port 12 in a state where the weak seal portion 18 of the medicine bag 10 is not opened. Is to prevent access. The medicine discharge prevention device 28 is formed of a plastic molded product such as polyethylene, and has sufficient hardness and / or thickness to prevent puncture by the puncture needle. The medicine discharge prevention device 28 includes a first half portion 28A (FIG. 1) and a second portion 28B (FIG. 2) each having a shape in which the cylindrical body is halved. The first part and the second part 28A, 28B are arranged so as to sandwich the medicine bag 10 from above and below, and in this embodiment, have the same shape, and the first part and the second part 28A, From 28B, a rectangular plate-shaped first flap 30 and second flap 32 respectively extend integrally. The first and second flaps 30 and 32 constitute the engaging member of the present invention. FIG. 3 shows the combined state of the upper and lower halved portions 28A and 28B in cross section, and a cavity 34 for accommodating the discharge port 12 is formed between the halved portions 28A and 28B. As shown in FIGS. 1 and 2, the cavity 34 has a relatively large margin with respect to the outer diameter of the discharge port 12 on the drug bag 10 side (the upper end side in FIGS. 1 and 2). The lower end side in FIGS. 1 and 2 is substantially complementary to the flange portion 12-2 and the cap 12-3. As shown in FIGS. 1 and 2, the halved portions 28A and 28B are provided with some enlarged diameter portions 28A-1 and 28B-1 on the lower end side. As shown in FIG. 1 and FIG. 3, a window portion 29 is formed, and a flange portion 12-2 of the discharge port 12 extends into the window portion 29. Therefore, by combining the half portions 28A and 28B so that the medicine bag 10 is sandwiched from above and below, the medicine discharge prevention tool 28 can be mounted on the discharge port 12 substantially without backlash. When the halved portions 28A and 28B are combined, the end surfaces 28A-2 and 28B-2 constitute one disc-shaped puncture prevention surface. Therefore, as shown in FIG. 2, even if an attempt is made to puncture the rubber inner lid 23 of the discharge port 24 with the puncture needle 24 of the infusion set, the puncture is performed by the puncture prevention surface (28A-2, 28B-2) of the drug discharge prevention device 28. The needle 24 is blocked and the puncture needle 24 cannot be inserted. An end portion of a tamper seal provided on the upper surface of the rubber plug 28 in the discharge port 12 can be extended from the window portion 29.

図3に示すように薬剤排出阻止具28の上下の半割本体28A, 28Bその端面28A-2, 28B-2における直径縁部36にて当接される。そのため、第1フラップ30と第2フラップ32とは直径縁部36を中心に図3の閉鎖状態と図4の開放状態との間で回動することができる。   As shown in FIG. 3, the upper and lower halved bodies 28A, 28B of the medicine discharge prevention tool 28 are brought into contact with the diameter edge portions 36 on the end faces 28A-2, 28B-2. Therefore, the first flap 30 and the second flap 32 can rotate around the diameter edge 36 between the closed state of FIG. 3 and the open state of FIG.

この実施形態では以下説明するように雌雄の係合部の180度対称配置により上下の半割本体28A, 28Bは完全同一形状のものすることができ、一つの金型により成形することができ、成形コストの削減を実現することができる。次に、この雌雄の係合部の構成について説明すると、図5(イ)は上下の半割本体28A, 28Bの分離状態を示し、各半割本体28A, 28Bはその直径面における対称位置に雄係合部38及び雌係合部40を備えている。雄係合部38は半割本体28A, 28Bの半割面から直交方向に延出され、雄係合部38は図6に示すように下端に軸線方向に僅か突出する係合突起38Aを備える。雌係合部40は雄係合部38を収容するための矩形空洞部40-1を形成し、この空洞部40-1における薬剤排出阻止具軸線に直交する壁面40Aに図6に示すような係合片40-2が突出形成され、この係合片40-2は壁面40Aから最初は直交するように突出するが、自由端40-2'は幾分下向きに曲折される(背面側に傾斜面を形成する)。上下の半割本体28A, 28Bの合体時に、半割本体28A, 28Bは薬剤バッグを上下から挟むように配置され、排出口12を介して相互に向き合う方向(図6(イ)の矢印a)に相対移動される。半割本体28A, 28Bにおける雄係合部38及び雌係合部40の180度配置故に、図6(イ)に示すように上下の半割本体28A, 28B間で雄係合部38と雌係合部40とが対向している。そのため、雄係合部38は対向する雌係合部40に挿入され、挿入の過程で雄係合部38の係合突起38Aは雌係合部40の係合片40-2と当接するが、係合片40-2の自由端40-2'がやや下向きに傾斜しているため、雄係合部38が幾分弾性的に撓むことと相まって雄係合部38は係合片40-2を乗り越え、乗り越えた後は撓みは弾性により復帰され係合突起38Aが係合片40-2に裏面側にて係合する図6(ロ)の状態が得られる。そのため、図5(ロ)に示すように第1の半割部分28Aと第2の半割部分28Bとは雄雌の係合部38, 40により所定の弾性力にて合体保持される。   In this embodiment, as will be described below, the upper and lower halved bodies 28A, 28B can be of the same shape due to the 180-degree symmetrical arrangement of the male and female engaging portions, and can be formed by a single mold, Reduction of molding cost can be realized. Next, the structure of the male and female engaging portions will be described. FIG. 5 (a) shows the separated state of the upper and lower halved main bodies 28A and 28B, and the halved main bodies 28A and 28B are in symmetrical positions on their diameter surfaces. A male engaging portion 38 and a female engaging portion 40 are provided. The male engaging portion 38 extends in an orthogonal direction from the halved surfaces of the halved main bodies 28A and 28B, and the male engaging portion 38 includes an engaging protrusion 38A that slightly protrudes in the axial direction at the lower end as shown in FIG. . The female engaging part 40 forms a rectangular cavity 40-1 for accommodating the male engaging part 38, and a wall surface 40A perpendicular to the axis of the medicine discharge prevention tool in this cavity 40-1 is as shown in FIG. An engaging piece 40-2 is formed so as to protrude, and this engaging piece 40-2 initially protrudes perpendicularly from the wall surface 40A, but the free end 40-2 'is bent somewhat downward (to the rear side). Forming an inclined surface). When the upper and lower halved main bodies 28A and 28B are combined, the halved main bodies 28A and 28B are arranged so as to sandwich the drug bag from above and below, and face each other via the discharge port 12 (arrow a in FIG. 6 (a)). Is moved relative to Due to the 180 degree arrangement of the male engaging portion 38 and the female engaging portion 40 in the halved main bodies 28A, 28B, the male engaging portion 38 and the female halves between the upper and lower halved main bodies 28A, 28B as shown in FIG. The engaging part 40 is opposed. Therefore, the male engaging portion 38 is inserted into the opposing female engaging portion 40, and the engaging protrusion 38A of the male engaging portion 38 contacts the engaging piece 40-2 of the female engaging portion 40 during the insertion process. Since the free end 40-2 'of the engagement piece 40-2 is inclined slightly downward, the male engagement portion 38 is coupled with the engagement piece 40 in combination with the elastic deformation of the male engagement portion 38. After overriding -2, the bending is restored by elasticity, and the state shown in FIG. 6 (b) is obtained in which the engagement protrusion 38A engages with the engagement piece 40-2 on the back surface side. Therefore, as shown in FIG. 5B, the first half portion 28A and the second half portion 28B are held together by a predetermined elastic force by the male and female engaging portions 38, 40.

図1及び図2に示すように上下のフラップ30, 32は上面より見ると実質的に矩形状であるが、図7に示すように先端部以外では湾曲形状をなしており、この湾曲形状部位では上下のフラップ30, 32は薬液バッグ10とは完全非接触である。しかしながら、フラップ30, 32は両側端部30-1, 32-1及び先端部30-2, 32-2では平坦であり、上下より薬液バッグ10と係合し、薬液バッグ10を図7に示すようこの係合部位において実質的に平坦に潰し、薬液バッグ10を挟着保持することができる。更に、フラップ30, 32は湾曲形状部位から図3及び図8に示す平坦な先端部30-2, 32-2に接続しているが、この平坦な先端部30-2, 32-2において幅方向の両端30-2', 32-2'は図8のように内面も平坦で、薬液バッグ10の対向面と接触しているが、幅方向における中間部の内面は30A, 30Bにて示すように凹面をなしており、薬液バッグ10の対向面とは実質的に非接触(若しくは軽微な接触状態)である。図1において、上下のフラップ30, 32における薬液バッグ接触部と非接触部との境界線を 両側端部30-1, 32-1についてはB1にて、先端部30-2, 32-2についてはB2にて示す。これらの境界線B1, B2は図1に示すように薬剤バッグ平面における排出口12の直径の外側に位置しており、排出口12の軸線延長部位、即ち幅方向の局部、例えば中間部では上下のフラップ30, 32は薬剤バッグ10の対向面と非接触である。即ち、排出口12の軸上延長部位では薬液バッグ10は上下のフラップ30, 32に対して非拘束(フリー)である。   As shown in FIGS. 1 and 2, the upper and lower flaps 30 and 32 are substantially rectangular when viewed from above, but as shown in FIG. Then, the upper and lower flaps 30 and 32 are not completely in contact with the chemical solution bag 10. However, the flaps 30 and 32 are flat at both side end portions 30-1 and 32-1 and front end portions 30-2 and 32-2, and engage with the chemical solution bag 10 from above and below, and the chemical solution bag 10 is shown in FIG. Thus, the liquid bag 10 can be clamped and held substantially flat at the engagement site. Further, the flaps 30 and 32 are connected to the flat tip portions 30-2 and 32-2 shown in FIGS. 3 and 8 from the curved portion, and the flat tips 30-2 and 32-2 have a width. Both ends 30-2 'and 32-2' in the direction are flat on the inner surface as shown in FIG. 8 and are in contact with the opposite surface of the drug solution bag 10, but the inner surfaces of the intermediate portion in the width direction are indicated by 30A and 30B. Thus, the surface is substantially non-contact (or in a slight contact state) with the opposing surface of the drug solution bag 10. In FIG. 1, the boundary line between the liquid bag contact part and the non-contact part in the upper and lower flaps 30 and 32 is indicated by B1 for both side end parts 30-1 and 32-1, and for the front end parts 30-2 and 32-2. Is indicated by B2. As shown in FIG. 1, these boundary lines B1 and B2 are located outside the diameter of the discharge port 12 in the plane of the medicine bag, and the axial extension portion of the discharge port 12, that is, a local portion in the width direction, for example, the upper and lower portions The flaps 30 and 32 are not in contact with the opposite surface of the drug bag 10. In other words, the drug solution bag 10 is not restrained (free) with respect to the upper and lower flaps 30 and 32 at the axially extended portion of the discharge port 12.

図3は薬剤バッグ10への薬剤排出阻止具28の装着状態を軸線に沿った断面にて示し、薬剤バッグ10はこの状態で出荷される。弱シール部18は未開通であり、各隔室20, 22にそれぞれの薬液が個別的に収容され、隔室20, 22に収容される薬液の分だけ薬剤バッグ10は膨れている。隔室22に開口するように薬剤バッグ10の強シール部14に設けられた排出口12は薬剤排出阻止具28によりカバーされている。即ち、薬剤バッグ10の片面側に第1フラップ30が当てがわれ(図1参照)、薬剤バッグ10を挟んで反対側には第2フラップ32が当てがわれ、第1フラップ30と第2フラップ32とは薬剤バッグ10を挟んで合体せしめられ、図7及び図8に示すように上下のフラップ30, 32はその湾曲形状部位の両側の平坦部30-1, 32-1及び湾曲形状部位に連なる平坦先端部30-2, 32-2における平坦内面部位30-2', 32-2'にて薬液バッグを介して当接され、排出口12の軸線における両側部位において薬剤バッグ10は実質的に平坦に潰される。   FIG. 3 shows a state in which the medicine discharge preventing device 28 is attached to the medicine bag 10 in a cross section along the axis, and the medicine bag 10 is shipped in this state. The weak seal portion 18 is not opened, the respective chemical solutions are individually stored in the compartments 20 and 22, and the drug bag 10 is expanded by the amount of the chemical solution stored in the compartments 20 and 22. The discharge port 12 provided in the strong seal portion 14 of the medicine bag 10 so as to open into the compartment 22 is covered with a medicine discharge prevention tool 28. That is, the first flap 30 is applied to one side of the drug bag 10 (see FIG. 1), and the second flap 32 is applied to the opposite side of the drug bag 10 between the first flap 30 and the second flap. 32, the medicine bag 10 is sandwiched between the upper and lower flaps 30 and 32, as shown in FIGS. 7 and 8, and flat portions 30-1, 32-1 on both sides of the curved portion and curved portions. The flat inner portions 30-2 'and 32-2' of the continuous flat tip portions 30-2 and 32-2 are brought into contact with each other through the drug solution bag, and the drug bag 10 is substantially at both side portions in the axis of the discharge port 12. Flatly crushed.

この発明に従い上下のフラップ30, 32を両側の平坦部30-1, 32-1以外は湾曲状としかつ先端平坦部30-2, 32-2の幅方向の中間部を凹面30A, 32B(図7)としたことによるフリーの空間部の存在は薬液バッグ10への薬剤排出阻止具28の装着時に薬液バッグを構成する合成樹脂フィルムに生じた皺の引き伸ばしに役立てることができる。これを引用文献1における従来の対比において説明すると、図9(イ)は従来技術における排出口112に対する薬剤バッグ110の付け根の部分を模式化して示しており、薬剤排出阻止具128の装着時この付け根の部分においてフラップ130, 132により薬剤バッグ110は潰される。フラップ130, 132は全幅方向(図9の紙面直交方向)で平坦な底面をなしており、そのため、フラップ130, 132は実質的全幅において薬液バッグ110を構成する合成樹脂フィルム対向面に当接せしめられる。薬剤バッグ110を構成する合成樹脂フィルムは排出口112の上下直径部位では排出口の形状に準じて丸みを帯びているが排出口112に直近した平坦なフラップ130, 132間で圧潰されるため、排出口112に対する付け根部位110'で形状が丸から平に急変し皺が発生しやすい。そして、上下のフラップ130, 132は全幅において薬剤バッグ110対向面に当接し、かつ上下から弾性力下で薬剤バッグを保持している。したがって、薬剤排出阻止具の装着時に付け根110'の部位で合成樹脂フィルム面に生じた皺は固定されてしまい、薬液バッグ110を引っ張っても延びず、皺のまま出荷されることにより輸送等の取り扱い中にピンホールなどの欠陥発生の恐れがあった。   According to the present invention, the upper and lower flaps 30, 32 are curved except for the flat portions 30-1, 32-1 on both sides, and the intermediate portions in the width direction of the tip flat portions 30-2, 32-2 are concave surfaces 30A, 32B (see FIG. The presence of the free space portion due to 7) can be used for stretching the wrinkles generated on the synthetic resin film constituting the chemical solution bag when the chemical discharge preventing device 28 is attached to the chemical solution bag 10. This will be explained in the conventional comparison in the cited document 1. FIG. 9A schematically shows the base portion of the drug bag 110 with respect to the discharge port 112 in the prior art. The drug bag 110 is crushed by the flaps 130 and 132 at the base portion. The flaps 130 and 132 have a flat bottom surface in the entire width direction (in the direction orthogonal to the paper surface in FIG. 9). Therefore, the flaps 130 and 132 are brought into contact with the opposing surface of the synthetic resin film constituting the drug solution bag 110 in substantially the entire width. It is done. The synthetic resin film constituting the drug bag 110 is rounded in accordance with the shape of the discharge port at the upper and lower diameter portions of the discharge port 112, but is crushed between the flat flaps 130 and 132 immediately adjacent to the discharge port 112. At the base portion 110 ′ with respect to the discharge port 112, the shape suddenly changes from a round shape to a flat shape, and wrinkles are likely to occur. The upper and lower flaps 130 and 132 are in contact with the opposite surface of the drug bag 110 in the entire width, and hold the drug bag under elastic force from above and below. Therefore, the bag generated on the surface of the synthetic resin film at the base 110 'when the drug discharge prevention device is mounted is fixed, and does not extend even when the drug solution bag 110 is pulled. There was a risk of pinholes and other defects during handling.

図9(ロ)はこの発明における排出口12に対する薬剤バッグ10の付け根の部分を図9(イ)との対比上模式化して示しており、フラップ30, 32は底面30A, 30Bを凹面(図7)としており、そのため、排出口12の軸上延長部位では薬液バッグと非接触(フリー)である。そのため、薬液バッグ10に対する薬剤排出阻止具装着時に排出口12に対する薬液バッグ10の付け根の部位10´に皺が発生しても、薬液バッグ10と排出口12とを相対的に矢印cの方向に相対変位させることにより薬剤バッグ10を構成する合成樹脂フィルムは緊張を受け、付け根の部位10´に皺の発生が仮にあったとしてもこれを引き延ばし、無皺の状態とすることができる。そのため、輸送中に皺の部位に無理な力が掛かって皺の部位からピンホールが発生してしまう、という懸念はない。   FIG. 9 (b) schematically shows the base portion of the drug bag 10 with respect to the discharge port 12 according to the present invention in comparison with FIG. 9 (a), and the flaps 30 and 32 have bottom surfaces 30A and 30B with concave surfaces (FIG. 9). 7). Therefore, the axial extension portion of the discharge port 12 is not in contact (free) with the chemical solution bag. For this reason, even when wrinkles occur at the base portion 10 'of the chemical solution bag 10 with respect to the discharge port 12 when the drug discharge preventing device is attached to the chemical solution bag 10, the chemical solution bag 10 and the discharge port 12 are relatively moved in the direction of the arrow c. By making the relative displacement, the synthetic resin film constituting the drug bag 10 is strained, and even if wrinkles are generated at the base portion 10 ′, the synthetic resin film can be extended to be free of wrinkles. Therefore, there is no concern that an excessive force is applied to the heel portion during transportation and pinholes are generated from the heel portion.

そして、このような薬剤排出阻止具28の装着状態では、第1及び第2の半割部分28A, 28B間に形成された空洞34(図3)に排出口12は収容され、プラスチックの薬剤排出阻止具28により穿刺針24がブロックされるため、排出口24のゴム製内蓋23を穿刺は行い得ない。そして、第1及び第2のフラップ30, 32間で対向する雄雌の係合部材38, 40が係合するため、第1フラップ30、第2フラップ32を当接部36の廻りで回動させようとしても、雄雌の係合部材38, 40の弾性はそれに抵抗し、薬剤排出阻止具を簡単には開けることはできない。   When the medicine discharge preventing device 28 is mounted, the discharge port 12 is accommodated in the cavity 34 (FIG. 3) formed between the first and second halved portions 28A and 28B, and the plastic medicine is discharged. Since the puncture needle 24 is blocked by the blocking tool 28, the rubber inner lid 23 of the discharge port 24 cannot be punctured. Then, since the male and female engaging members 38, 40 facing each other between the first and second flaps 30, 32 are engaged, the first flap 30 and the second flap 32 are rotated around the contact portion 36. Even if it tries to make it, the elasticity of the male and female engaging members 38 and 40 resists it, and the medicine discharge prevention tool cannot be easily opened.

薬剤バッグ10の開通のため薬剤バッグ10は机などの上に図3のように平坦に載置され、薬剤バッグ10は上面より手のひらで矢印bのように加圧される(図3では隔室20側において薬剤バッグ10を加圧しているが隔室22の側を加圧しても両側を加圧してもよい)。薬剤バッグ10の加圧により弱シール部18に液圧が加わり、所定の圧力により弱シール部18は瞬時に破壊開通(若しくは剥離)するに至る。加圧により薬剤バッグ10の内圧は高められており、弱シール部18の開通によりこの高められた圧力が一気に放出されるため、衝撃的な薬液の流れが薬剤バッグ10内に惹起される。薬剤バッグ10内に惹起された衝撃的な薬液の流れを図4では矢印Fにより模式的に示す。弱シール部18の開通の際に薬剤バッグ10内に惹起された急激な薬液の流れFは、第1フラップ30及び第2フラップ32薬液バッグ10と湾曲形状部における両端部30-1, 32-1及び先端平坦部30-2, 32-2における両端部30-2', 32-2'に当接していることから、薬剤バッグ10を拡開させ、拡開された薬剤バッグ10の対向面に当接した第1フラップ30及び第2フラップ32は雄雌の係合部材38, 40の係合による弾性拘束力に抗して当接部36の廻りで図4のように回動せしめられ雄雌の係合部材38, 40は図6(ロ)の係合状態から(イ)の離脱状態とされ、薬剤排出阻止具は排出口12から離脱・除去される。そのため、排出口12は剥き出しとなりゴム栓23に輸液セットの穿刺針を刺入することで点滴作業を開始することができる。   In order to open the drug bag 10, the drug bag 10 is placed flat on a desk or the like as shown in FIG. 3, and the drug bag 10 is pressurized as shown by an arrow b from the top with a palm (in FIG. 3, a compartment). The medicine bag 10 is pressurized on the 20 side, but the compartment 22 side or both sides may be pressurized). The liquid pressure is applied to the weak seal portion 18 by pressurization of the medicine bag 10, and the weak seal portion 18 is instantaneously broken and opened (or peeled) by a predetermined pressure. The internal pressure of the drug bag 10 is increased by the pressurization, and this increased pressure is released at once by opening the weak seal portion 18, so that a shocking flow of the drug solution is induced in the drug bag 10. In FIG. 4, the flow of the shocking chemical liquid that is induced in the drug bag 10 is schematically indicated by an arrow F. The rapid flow F of the chemical solution induced in the drug bag 10 when the weak seal portion 18 is opened causes the first flap 30 and the second flap 32 of the drug solution bag 10 and both end portions 30-1, 32- in the curved shape portion. 1 and the tip flat portions 30-2 and 32-2 are in contact with both end portions 30-2 ′ and 32-2 ′, so that the drug bag 10 is expanded, and the opposite surface of the expanded drug bag 10 is The first flap 30 and the second flap 32 which are in contact with each other are rotated around the contact portion 36 as shown in FIG. 4 against the elastic restraining force due to the engagement of the male and female engaging members 38 and 40. The male and female engaging members 38, 40 are changed from the engaged state of FIG. 6 (b) to the disengaged state of (a), and the medicine discharge prevention tool is detached and removed from the discharge port 12. Therefore, the discharge port 12 is exposed, and the drip operation can be started by inserting the puncture needle of the infusion set into the rubber plug 23.

図1はこの発明の薬剤排出阻止具を備えた薬剤バッグの平面図(図3のI方向矢視図)である。FIG. 1 is a plan view (viewed in the direction of arrow I in FIG. 3) of a medicine bag provided with the medicine discharge preventing device of the present invention. 図2は図3の大略II−II線に沿った矢視図であり、薬剤排出阻止具の下側半分を示すものでである。FIG. 2 is an arrow view taken along line II-II in FIG. 3 and shows the lower half of the medicine discharge prevention tool. 図3はこの発明の薬剤排出阻止具を備えた薬剤バッグの縦方向断面図(図1のIII−III線に沿って表される矢視断面図)である。FIG. 3 is a longitudinal cross-sectional view (a cross-sectional view taken along the line III-III in FIG. 1) of a drug bag provided with the drug discharge preventing device of the present invention. 図4は薬剤バッグ開通時における図3の薬剤排出阻止具の解除状態を示す部分的断面図である。FIG. 4 is a partial cross-sectional view showing a released state of the medicine discharge prevention device of FIG. 3 when the medicine bag is opened. 図5は第1及び第2フラップを弾性下で合体拘束せしめる弾性拘束手段を示しており、図1のV−V線に沿って表される矢視断面図であり、(イ)は分離状態、(ロ)は係合状態を示すものである。FIG. 5 shows an elastic restraining means for restraining the first and second flaps together under elasticity, and is a cross-sectional view taken along the line V-V in FIG. 1. , (B) show the engaged state. 図6は弾性拘束手段の詳細構成図であり、図5のVI−VI線に沿って表される矢視断面図であり、(イ)は分離状態、(ロ)は係合状態を示すものである。6 is a detailed configuration diagram of the elastic restraining means, and is a cross-sectional view taken along line VI-VI in FIG. 5, where (A) shows a separated state and (B) shows an engaged state. It is. 図7は薬液バッグに対する上下のフラップの湾曲部位の両端の当接状態を示す図(図1のVII−VII線に沿った矢視断面図)である。FIG. 7 is a view (a cross-sectional view taken along the line VII-VII in FIG. 1) showing a contact state of both ends of the curved portion of the upper and lower flaps with respect to the chemical solution bag. 図8は薬液バッグに対する上下のフラップの先端平坦部の当接状態を示す図(図1のVIII−VIII線に沿った矢視断面図)である。FIG. 8 is a diagram (a cross-sectional view taken along the line VIII-VIII in FIG. 1) showing a contact state of the tip flat portions of the upper and lower flaps with respect to the chemical solution bag. 図9は排出口に対する薬液バッグの付け根の部分の拡大図であり、従来技術(イ)と本発明(ロ)とを対比して模式化して示す図である。FIG. 9 is an enlarged view of the base portion of the chemical solution bag with respect to the discharge port, and is a diagram schematically showing the prior art (A) and the present invention (B) in comparison.

符号の説明Explanation of symbols

10…薬剤バッグ
10´…排出口に対する薬剤バッグの付根部分
12…排出口
18…弱シール部
20, 22…隔室
23…ゴム製内蓋
28…薬剤排出阻止具
28A, 28B…薬剤排出阻止具の上下の半割部分
30, 32…上下のフラップ
30A, 32A…上下のフラップにおける凹状底面
38…拘束部材
40…係合溝
DESCRIPTION OF SYMBOLS 10 ... Drug bag 10 '... The root part 12 of the medicine bag with respect to a discharge port ... Discharge port 18 ... Weak seal part
20, 22 ... Compartment 23 ... Rubber inner lid 28 ... Drug discharge prevention device
28A, 28B… Upper and lower halves of the drug discharge prevention device
30, 32… Upper and lower flaps
30A, 32A ... concave bottom surface 38 in upper and lower flaps ... restraining member 40 ... engagement groove

Claims (5)

可撓性膜素材にて形成され、弱シールによりその内部が薬剤を個別に収容する複数の隔室に区画された薬剤バッグと、薬剤バッグ外周部に取り付けられ、複数の隔室の一つに開口する排出口と、薬剤バッグの外部に装着され、弱シール未開通時に排出口からの薬剤の排出を阻止する薬剤排出阻止具とを備え、前記薬剤排出阻止具は排出口を挟んで対向され、薬剤バッグの開通時の薬液バッグの膨れ変形に協働せしめる一対の係合部材と、前記係合部材を通常状態において合体拘束し、排出口へのアクセスを阻止するが、係合部材が薬液バッグの膨れ変形と協働時に薬剤排出阻止具を薬液バッグから離脱せしめるべく拘束状態が解除される拘束部材とを具備し、前記一対の係合部材の対向面は排出口の実質的延長部位において薬剤バッグを実質的にフリーとする形状をなす複室容器。   A drug bag formed of a flexible membrane material, the inside of which is partitioned by a weak seal into a plurality of compartments that individually contain the medicines, and attached to the outer periphery of the medicine bag, to one of the plurality of compartments A discharge port that opens, and a drug discharge blocking device that is attached to the outside of the drug bag and blocks discharge of the drug from the discharge port when the weak seal is not opened, the drug discharge blocking device being opposed to each other across the discharge port A pair of engaging members that cooperate with the swelling deformation of the drug solution bag when the drug bag is opened, and the engagement members are combined and restrained in a normal state to prevent access to the discharge port. A restraining member which is released from a restrained state so that the medicine discharge preventing device can be detached from the drug solution bag when cooperating with the bulging deformation of the bag, and the opposing surfaces of the pair of engaging members are substantially extended portions of the discharge port Drug bag real Multiple chambers in the shape of free to. 可撓性膜素材にて形成され、弱シールによりその内部が薬剤を個別に収容する複数の隔室に区画された薬剤バッグと、薬剤バッグ外周部に取り付けられ、複数の隔室の一つに開口する排出口と、薬剤バッグの外部に装着され、弱シール未開通時に排出口からの薬剤の排出を阻止する薬剤排出阻止具とを備え、前記薬剤排出阻止具は排出口を挟んで対向され、薬剤バッグの開通時の薬液バッグの膨れ変形に協働せしめる一対の係合部材と、前記係合部材を通常状態において合体拘束し、排出口へのアクセスを阻止するが、係合部材が薬液バッグの膨れ変形と協働時に薬剤排出阻止具を薬液バッグから離脱せしめるべく拘束状態が解除される拘束部材とを具備し、前記一対の係合部材の対向面は幅方向において局部的に薬剤バッグを実質的にフリーとする形状をなす複室容器。   A drug bag formed of a flexible membrane material, the inside of which is partitioned by a weak seal into a plurality of compartments that individually contain the medicines, and attached to the outer periphery of the medicine bag, to one of the plurality of compartments A discharge port that opens, and a drug discharge blocking device that is attached to the outside of the drug bag and blocks discharge of the drug from the discharge port when the weak seal is not opened, the drug discharge blocking device being opposed to each other across the discharge port A pair of engaging members that cooperate with the swelling deformation of the drug solution bag when the drug bag is opened, and the engagement members are combined and restrained in a normal state to prevent access to the discharge port. A restraining member that is released from a restrained state so that the medicine discharge preventing device can be detached from the chemical solution bag when cooperating with the swelling deformation of the bag, and the opposing surfaces of the pair of engaging members are locally in the width direction. Substantially free Multiple chambers in the shape of a. 請求項1若しくは2に記載の発明において、前記一対の係合部材の対向面は少なくとも一方が凹面状に形成される複室容器。   The multi-chamber container according to claim 1 or 2, wherein at least one of the opposing surfaces of the pair of engaging members is formed in a concave shape. 請求項1若しくは2に記載の発明において、前記拘束部材は弾性力により一対の係合部材を合体拘束する複室容器。   3. The multi-chamber container according to claim 1, wherein the restraining member restrains the pair of engaging members by an elastic force. 可撓性膜素材にて形成された薬剤バッグの内部を弱シールにより複数の隔室に区画し、区画された夫々の隔室に薬剤を収容し、薬剤バッグの外周部に複数の隔室に一方に開口するように排出口を装着すると共に、一対の係合部材と前記係合部材を合体拘束する拘束部材とからなる薬剤排出阻止具を、前記一対の係合部材が排出口を挟んで対向し薬剤バッグの開通時の薬液バッグの膨れ変形に協働せしめて拘束部材を解除せしめるようかつ排出口の実質的延長部位においては薬剤バッグをフリーとするように装着し、薬剤排出阻止具装着後に薬剤バッグと薬剤排出阻止具とを幾分相対変位させて前記非接触部位を介して可撓性膜素材を緊張させて可撓性膜素材に皺の発生があればこれを解消する方法。   The inside of the medicine bag formed of a flexible membrane material is divided into a plurality of compartments by weak sealing, the medicine is accommodated in each compartment, and the medicine bag is provided with a plurality of compartments on the outer periphery. A discharge outlet is mounted so as to open to one side, and a medicine discharge prevention tool comprising a pair of engaging members and a restraining member that combines and restrains the engaging members is sandwiched between the pair of engaging members. Attach the medicine bag so that the restraint member is released by cooperating with the swelling deformation of the medicine bag when the medicine bag is opened and the medicine bag is free at the substantial extension part of the discharge port. A method of resolving wrinkles in the flexible membrane material by causing the flexible membrane material to be strained through the non-contact portion by relatively displacing the drug bag and the drug discharge prevention device later.
JP2007061213A 2007-03-12 2007-03-12 Multi-chamber container Expired - Fee Related JP4924936B2 (en)

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