JP2008194270A - Biosensor cartridge and its manufacturing method - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a biosensor cartridge which can be mounted on and set to a measuring instrument without removing a protection cap at the distal end of the measuring instrument, and its manufacturing method. <P>SOLUTION: By locking the locking part 23 of a base 21 provided with a clamping projection 20 into the locking notch part 12 of a chip main body 11, the clamping projection 20 can be easily installed later. At the same time, a puncture tool 22 can be easily installed later. Thus, the clamping projection 20 can be attached even to the already manufactured biosensor cartridge 10 by providing the locking notch part 12, and the biosensor cartridge 10 can be easily attached to/removed from the measuring instrument 31 without removing the protection cap 33 of the measuring instrument 31 by clamping the clamping projection 20 with fingers by a user. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a biosensor cartridge for measuring and analyzing a chemical substance using a reagent accommodated in a hollow reaction part of a chip, for example.

Conventionally, a biosensor in which a biosensor chip and a lancet are integrated has been disclosed (see, for example, Patent Document 1).
FIG. 15A is a perspective view of the sensor described in Patent Document 1, and FIG. 15B is an exploded perspective view of the sensor. As shown in FIG. 15, the lancet-integrated sensor 100 includes a chip body 101, a lancet 103, and a protective cap 105. The chip body 101 has a cover 101a and a substrate 101b that can be opened and closed, and an internal space 102 is formed on the inner surface of the cover 101a. The internal space 102 has a shape that allows the lancet 103 to be movably accommodated, and the lancet 103 can be exchanged by opening the cover 101a.

  The needle 104 provided at the tip of the lancet 103 can be moved in and out from an opening 102 a formed at the front end of the internal space 102 of the chip body 101 as the lancet 103 moves. The lancet 103 can be fixed to the chip body 101 by pressing both sides of the chip body 101 with a finger and pressing the projection 103a of the lancet 103, and puncture is performed in this fixed state. The protective cap 105 has a tube portion 105 a into which the needle 104 is inserted, and the tube portion 105 a can be accommodated inside the chip body 101 as the needle 104 moves. Therefore, in the state before use, the protective cap 105 is put on the needle 104 to protect the needle 104 and prevent the user from being injured accidentally. Note that the substrate 101b is provided with a pair of electrode terminals 106 so that it can be electrically connected to a measuring apparatus (not shown).

Therefore, in use, the protective cap 105 is removed, the lancet 103 is pushed, the needle 104 is protruded from the chip body 101, and both sides of the chip body 101 are pressed with fingers to fix the needle 104. After puncturing the subject in this state, the needle 104 is housed inside the chip body 101, and the opening 102a provided at the front end of the chip body 101 is brought close to the puncture port to collect the outflowed blood.
International Publication No. 02/056769 Pamphlet (Figure 1)

However, in the lancet-integrated sensor 100 described in Patent Document 1 described above, the lancet 103 having the needle 104 is movably accommodated with respect to the chip body 101, so that the structure is complicated and the manufacture is troublesome. It may be possible to increase the size and the manufacturing cost. In such a lancet-integrated sensor, the operation of removing the protective cap is complicated in the operation of setting the lancet with a puncture device.
Therefore, the present inventors have intensively studied a biosensor cartridge that can be punctured and measured continuously and that can be easily mounted and set in a measuring device having a protective cap at the tip.

  An object of the present invention is to provide a biosensor cartridge that can be easily mounted and set without removing the protective cap at the tip of the measuring apparatus and a method for manufacturing the same.

  In order to achieve the above-described object, a biosensor cartridge according to the present invention is a biosensor cartridge having a chip body and a puncture device fixedly provided at a tip of the chip body, the biosensor cartridge being There is a gripping protrusion protruding in a direction penetrating both the front and back surfaces of the chip body.

  In the biosensor cartridge configured as described above, the user can easily handle the biosensor cartridge by holding the holding protrusion with a finger.

The biosensor cartridge according to the present invention can be attached to a measuring device, and when the biosensor cartridge is attached to the measuring device having a protective cap at the tip, the gripping protrusion is attached to the protective cap. It is desirable to be provided so as to protrude from the provided slit to the outside of the protective cap.

According to the above configuration, the biosensor cartridge can be easily attached to the measuring device without removing the protective cap of the measuring device.

  In the biosensor cartridge according to the present invention, the gripping protrusion is provided on a base that abuts on the chip body surface, and the base locks a locking notch provided by cutting the chip body. It is desirable to have a locking portion.

  In the biosensor cartridge configured as described above, the holding protrusion can be easily retrofitted by locking the locking portion of the base provided with the holding protrusion to the locking notch portion of the chip body. it can. At the same time, the puncture device can be easily retrofitted. Accordingly, even a biosensor chip that has already been manufactured can be used in the same manner by providing a locking notch.

  Further, in the biosensor cartridge according to the present invention, the locking portion includes a locking protrusion penetrating the locking notch from the base that contacts one surface of the chip body, and the other surface of the chip body. It is preferable that the gripping projection protrudes from the base and the second base.

  In the biosensor cartridge configured as described above, the second holding protrusion is provided by passing the locking protrusion of the base provided with one gripping protrusion at the locking notch. The chip body is sandwiched and fixed between the base and the second base by fitting the base to the locking protrusion. As a result, the gripping projection can be easily retrofitted. At the same time, the puncture device can be easily retrofitted.

  Further, in the biosensor cartridge according to the present invention, the locking notch portion is provided at an outer edge portion along the longitudinal direction of the chip body, and the locking portion is provided so as to protrude from the outer edge portion of the lower surface of the base. A protrusion having a plurality of locking claws, wherein the holding protrusion protrudes from the upper and lower surfaces of the base, and the holding protrusion provided on the lower surface of the base is provided at the center of the chip body. It is desirable that the notch is provided so as to protrude through the notch for the opposite side of the base.

  In the biosensor cartridge configured as described above, one of the holding protrusions protruding from the lower surface of the base is passed through the protrusion notch provided in the center of the chip body, and the outer edge of the lower surface of the base The base is attached to the chip body by locking the locking notches provided on the outer edge of the chip body with the locking claws provided protruding from the portion. As a result, the gripping projection can be easily retrofitted. At the same time, the puncture device can be easily retrofitted.

  In the biosensor cartridge according to the present invention, the locking portion has a plurality of locking claws provided so as to protrude from the lower surface of the base, and the gripping protrusions protrude from both the upper and lower surfaces of the base. In addition, it is preferable that the gripping protrusion provided on the lower surface of the base is provided so as to protrude through the protrusion notch provided in the center of the chip body and to be opposite to the base.

  In the biosensor cartridge configured as described above, one of the holding protrusions protruding from the lower surface of the base is passed through the protrusion notch, and the locking provided protruding from the center of the lower surface of the base. The base is attached to the chip body by locking the locking notch provided at the center of the chip body with the claws. As a result, the gripping projection can be easily retrofitted. At the same time, the puncture device can be easily retrofitted.

  A biosensor cartridge manufacturing method according to the present invention is a biosensor cartridge manufacturing method for manufacturing the biosensor cartridge of the present invention, wherein a plurality of the chip bodies are integrally formed continuously, A plurality of the bases having the gripping protrusions are integrally formed continuously, and the base is locked to the chip body, and then the chip body and the base are separated together to manufacture a biosensor cartridge. It is.

  In the biosensor cartridge manufacturing method configured as described above, a plurality of chip bodies each provided with a locking notch and a protrusion notch are continuously formed, and a gripping protrusion, a locking part, and a puncture device are formed. A plurality of bases provided with are continuously formed. Since a plurality of continuous bases are attached to a plurality of continuous chip bodies and then separated into each chip body, a large number of biosensor cartridges can be manufactured at a time.

  According to the present invention, the holding protrusion can be easily attached later by locking the locking portion of the base provided with the holding protrusion to the locking notch portion of the chip body. At the same time, since the puncture device can be easily retrofitted, even with a biosensor chip that has already been manufactured, the gripping protrusion can be attached by providing a locking notch, and the user can attach the gripping protrusion with a finger. By gripping, an effect is obtained that the biosensor cartridge can be easily attached to and detached from the measuring device without removing the protective cap of the measuring device.

<First Embodiment>
DESCRIPTION OF EMBODIMENTS Hereinafter, embodiments according to the present invention will be described in detail with reference to the drawings.
FIG. 1 (A) is a front view showing a state in which the biosensor cartridge according to the first embodiment of the present invention is attached to a measuring device, FIG. 1 (B) is a side view seen from the B direction in FIG. 1 (A), 2 is a configuration diagram of the biosensor device, FIG. 3A is a side view of the biosensor cartridge, FIG. 3B is a plan view of the biosensor cartridge, and FIG. 3C is a view of the biosensor cartridge viewed from the rear. FIG. 3D is an end view of the biosensor cartridge as viewed from the front, FIG. 4A is a side view of the chip body, FIG. 4B is a plan view of the chip body, FIG. (B) is a front view and an end view showing the gripping projection.

  As shown in FIGS. 1 and 2, the biosensor cartridge 10A according to the embodiment of the present invention is attached to and driven by the driving means 32 (see FIG. 2) of the measuring device 31 to drive the tip 11a of the chip body 11A. A sample is punctured with a puncture needle 22 which is a puncture device provided so as to protrude from the sample, and blood such as a sample is collected. Further, the gripping projections 20 projecting outward from the slit 33a of the protective cap 33 attached to the tip of the measuring device 31 on the chip body 11A and movable along the slit 33a cover both the front and back surfaces of the chip body 11A. It protrudes in the penetrating direction.

  As shown in FIG. 3, in the biosensor cartridge 10A according to the first embodiment, the gripping protrusion 20 is provided on the base 21 that contacts the surface of the chip body 11A, and the base 21 is provided by cutting out the chip body 11A. In addition to having a locking portion 23 for locking the locking notch portion 12A, a puncture needle 22 is fixedly projected forward from the distal end surface 21a of the base.

  4A and 4B show an example of the chip body 11A. The chip body 11A has two substrates 14a and 14b facing each other and a spacer layer 15 sandwiched between the two substrates 14a and 14b. Detection electrodes 16a and 16b are provided on the surface of at least one substrate 14b of the two substrates 14a and 14b on the spacer layer 15 side, and tip portions (right end portions in FIG. 4B) are mutually connected. It is bent in an L shape in the opposite direction to maintain a predetermined interval. A hollow reaction portion 17 is formed by the two substrates 14a and 14b and the spacer layer 15 from the tip 11a of the chip body 11A to a portion where the two detection electrodes 16a and 16b face each other. A sample collection port 17 a for introducing blood as a sample collected by puncturing the sample with the puncture needle 12 to the hollow reaction unit 17 is provided at the tip of the hollow reaction unit 17. In the hollow reaction part 17, the detection electrodes 16a and 16b are exposed, and for example, an enzyme and a mediator are immobilized and reacted with glucose in blood immediately above or in the vicinity of the detection electrodes 16a and 16b in the hollow reaction part 17. A reagent 18 for generating an electric current is provided. Examples of the reagent 18 include enzymes such as glucose oxidase (GOD), glucose dehydrogenase (GDH), cholesterol oxidase, uricase, and electron acceptors. For example, in the case of a glucose biosensor chip that measures the amount of glucose in the blood, this portion includes a glucose oxidase layer, a glucose oxidase-electron acceptor (mediator) mixture layer, a glucose oxidase-albumin mixture layer, or a glucose oxidase-electron. A receptor-albumin mixture layer or the like is formed. These layers may be formed using enzymes other than glucose oxidase, such as glucose dehydrogenase. Moreover, you may include a buffering agent, a hydrophilic polymer, etc. in a chemical | medical agent as an additive. Accordingly, the hollow reaction part 17 is a part where blood such as blood collected from the sample collection port 17a undergoes a biochemical reaction with the reagent 18. At the center of the chip body 11A, two rectangular locking notches 12A and 12A are provided through the chip body 11A.

  As shown in FIG. 5, the locking portion 23 includes a locking protrusion 23 a that penetrates the locking notch 12 </ b> A of the chip body 11 </ b> A from the base 21 that contacts one surface of the chip body 11 </ b> A, and the other of the chip body 11 </ b> A. The surface of the second base 24 is provided with a locking recess 24a into which the locking protrusion 23a is fitted. . Note that gripping protrusions 20 and 20B are provided so as to protrude outward from the base 21 and the second base 24. The gripping protrusions 20 and 20B are larger than the outer shape of the protective cap 33 attached to the tip of the measuring device 31, and have a size that protrudes outside the protective cap 33 from the slit 33a. In addition, it is desirable to provide a recess 20a on the front end surface of the gripping projections 20 and 20B so that the biosensor cartridge can be securely gripped when the user grips it with a finger.

  As described above, according to the biosensor cartridge 10A according to the first embodiment described above, the user can grasp the grasping protrusions 20 and 20B with a finger without removing the protective cap 33 of the measuring device 31. 10A can be easily attached to and detached from the measuring device 31. Further, when the biosensor cartridge 10A is driven by the driving means 32 of the measuring device 31 and puncture is performed by the puncture needle 22 provided on the biosensor cartridge 10A, a gripping protrusion provided on the chip body 11A. Since 20 and 20B move along the slit 33a of the protective cap 33, it is possible to accurately puncture a predetermined puncture position.

  Further, by engaging the locking protrusion 23a of the base 21 provided with the gripping protrusion 20 with the locking notch 12A of the chip body 11A and fitting into the locking recess 24a of the second base 24, The gripping protrusions 20 and 20B can be easily attached later. At the same time, the puncture needle 22 can be easily retrofitted. Therefore, the chip body 11A that has already been manufactured can be used in the same manner by providing the locking notch 12A.

Second Embodiment
Next, a second embodiment according to the present invention will be described.
6A is a side view of the biosensor cartridge, FIG. 6B is a plan view of the biosensor cartridge, FIG. 6C is an end view of the biosensor cartridge viewed from the rear, and FIG. FIG. 7A is a side view of the chip body, FIG. 7B is a plan view of the chip body, FIG. 8A is a front view showing the gripping protrusion, and FIG. (B) and (C) are end views showing gripping projections. In addition, the same code | symbol is attached | subjected to the site | part which is already common in the site | part already mentioned above, and the overlapping description is abbreviate | omitted.

  As shown in FIGS. 6 and 7, in the chip body 11B of the biosensor cartridge 10B, a rectangular locking notch 12B is provided in the thickness direction of the chip body 11B on the outer edge portion along the longitudinal direction of the chip body 11B. It is provided through. Further, a rectangular projection notch 13 is provided in the center of the chip body 11B so as to penetrate the chip body 11B.

  As shown in FIGS. 6 and 8, a gripping protrusion 20 protrudes from the upper surface of the base 21, and a gripping protrusion 20 </ b> B protrudes from the flat portion 21 b of the base 21. Further, locking claws 25 are provided at the four corners of the flat portion 21b of the base 21 to engage with the locking notches 12B of the chip body 11B and lock the chip body 11B. The locking claw 25 includes an elastically deformable arm 25a having a length substantially equal to the thickness of the chip body 11B, and a claw 25b provided at the tip of the arm 25a.

  Accordingly, one gripping protrusion 20B that protrudes from the lower surface of the base 21 passes through the protrusion notch 13 provided in the center of the chip body 11B, and protrudes from the outer edge of the lower surface of the base 21. The locking claw 25 is used to lock the locking notch 12B provided on the outer edge of the chip body 11B. At this time, the arm 25a of the locking claw 25 is elastically deformed in the direction in which it is once expanded, and the locking notch 12B is locked by the claw 25b to attach the base to the chip body.

  As described above, according to the biosensor cartridge 10B according to the second embodiment described above, it is possible to obtain the same operations and effects as those of the biosensor cartridge 10A according to the first embodiment. Furthermore, since the holding projections 20 and 20B are provided on one base 21, the holding projections 20 and 20B and the puncture needle 22 can be retrofitted to the chip body 11B more easily.

<Third Embodiment>
Next, a third embodiment according to the present invention will be described.
9A is a side view of the biosensor cartridge, FIG. 9B is a plan view of the biosensor cartridge, FIG. 9C is an end view of the biosensor cartridge viewed from the rear, and FIG. 9D is the front FIG. 10A is a side view of the chip body, FIG. 10B is a plan view of the chip body, and FIG. 11A is a side view showing the gripping projection, FIG. (B) and (C) are end views showing gripping projections. In addition, the same code | symbol is attached | subjected to the site | part which is already common in the site | part already mentioned above, and the overlapping description is abbreviate | omitted.

  As shown in FIGS. 9 and 10, in the chip body 11C of the biosensor cartridge 10C, a rectangular protrusion notch 13 is provided in the center of the chip body 11C so as to penetrate the chip body 11C in the thickness direction. Yes. Further, on the front side of the protrusion notch 13, locking notch portions 12 </ b> C are provided penetrating in the thickness direction of the chip body 11 </ b> C on both left and right sides of the hollow reaction portion 17 so as to avoid the hollow reaction portion 17. Further, a locking notch 12C is also provided on the rear side of the protrusion notch 13.

  As shown in FIGS. 9 and 11, a gripping protrusion 20 protrudes from the upper surface of the base 21, and a gripping protrusion 20 </ b> B is also provided below the flat portion 21 b on the lower surface of the base 21. Further, the flat portion 21 b of the base 21 is provided with a pair of locking claws 26 a and 26 a on the front side of the gripping projection 20, and a locking claw 26 b is provided on the rear side of the gripping projection 20. ing. The locking claws 26a and 26b are composed of an arm 26a ′ having a length substantially equal to the thickness of the chip body 11C and a claw 26b ″ provided at the tip of the arm 26a ′.

  Accordingly, one gripping protrusion 20B that protrudes from the lower surface 21b of the base 21 passes through the protrusion notch 13 provided in the center of the chip body 11C, and protrudes from the outer edge of the lower surface of the base 21. The base 21 is attached to the chip body 11C by locking the locking notches 12C provided in the chip body 11C with the locking claws 26a and 26b provided.

  As described above, according to the biosensor cartridge 10C according to the third embodiment described above, it is possible to obtain the same operations and effects as those of the biosensor cartridge 10A according to the first embodiment. Further, since the holding projections 20 and 20B are provided on one base 21, the holding projections 20 and 20B and the puncture needle 22 can be retrofitted to the chip body 11C more easily.

  As shown in FIG. 12, the hollow reaction part 17 is provided obliquely, and one locking notch 12C is provided in front of the chip body 11D and in the center in the width direction, and the locking claw 27a also has a width of the base 21. One may be provided at the center in the direction.

<Fourth embodiment>
Next, a method for manufacturing a biosensor cartridge according to the fourth embodiment of the present invention will be described.
13A is a plan view showing a chip body formed continuously and integrally, FIG. 13B is a front view of a base formed continuously and integrally, and FIG. It is a front view showing a biosensor chip cut by attaching a continuous base to a continuous chip body. In addition, the same code | symbol is attached | subjected to the site | part which is already common in the site | part already mentioned above, and the overlapping description is abbreviate | omitted. Further, when common to the above-described embodiments, the reference numerals “A”, “B”, and “C” are removed, and “Biosensor cartridge 10” and “chip body 11” are indicated.

  In this biosensor cartridge manufacturing method, as shown in FIG. 13A, a plurality of chip bodies 11 are formed continuously and integrally, and as shown in FIG. A plurality of the bases 21 are formed continuously and integrally. Then, after the continuous base 21 is locked to the continuous chip body 11, the continuous chip body 11 and the base 21 are separated together to produce individual biosensor chips 10 as shown in FIG. To do. In FIG. 13, the case where the biosensor cartridge 10B described in the second embodiment is manufactured is illustrated, but the same applies to the first embodiment and the third embodiment.

  According to the biosensor cartridge manufacturing method described above, a plurality of chip bodies 11 provided with the locking notches 12 and the protrusion notches 13 are continuously formed integrally, and the gripping protrusions 20 and A plurality of bases 21 provided with locking portions 23 and puncture needles 22 are continuously formed integrally. Since a plurality of continuous bases 21 are attached to a plurality of continuous chip bodies 11 and then separated into each chip body 11, a large number of biosensor chips 10 can be manufactured at a time.

The biosensor chip and the manufacturing method thereof according to the present invention are not limited to the above-described embodiments, and appropriate modifications and improvements can be made.
For example, in each of the embodiments described above, the case where the gripping protrusions 20 are provided in the direction orthogonal to the front and back surfaces of the chip body 11 is illustrated, but in addition, as shown in FIG. It is also possible to provide gripping projections 20 in parallel with the chip body 11 on both the left and right sides of the base 20B.

  As described above, the biosensor chip and the manufacturing method thereof according to the present invention are configured to lock the gripping protrusion by locking the locking portion of the base provided with the gripping protrusion with the locking notch portion of the chip body. Can be easily retrofitted. At the same time, since the puncture device can be easily retrofitted, even with a biosensor chip that has already been manufactured, the gripping protrusion can be attached by providing a locking notch, and the user can attach the gripping protrusion with a finger. By gripping, the biosensor chip can be easily attached to and detached from the measuring device without removing the protective cap of the measuring device, and the chemical substance can be removed using the reagent contained in the hollow reaction part of the chip. It is useful as a biosensor chip for measurement and analysis.

(A) is a front view which shows the state which mounted | wore the measuring apparatus with the biosensor cartridge which concerns on 1st Embodiment of this invention. (B) is the side view seen from the B direction in FIG. 1 (A). It is a block diagram of a biosensor apparatus. (A) is a side view of the biosensor cartridge, (B) is a plan view of the biosensor cartridge, (C) is an end view of the biosensor cartridge as viewed from the rear, and (D) is an end surface of the biosensor cartridge as viewed from the front. FIG. (A) is a side view of a chip body. (B) is a plan view of the chip body. (A) and (B) are a front view and an end view showing a gripping projection. (A) is a side view of the biosensor cartridge, (B) is a plan view of the biosensor cartridge, (C) is an end view of the biosensor cartridge as viewed from the rear, and (D) is an end surface of the biosensor cartridge as viewed from the front. FIG. (A) is a side view of a chip body. (B) is a plan view of the chip body. (A) is a front view which shows the protrusion for holding | grip. (B) and (C) are end views showing gripping projections. (A) is a plan view of the biosensor cartridge, (B) is a front view of the biosensor cartridge, (C) is an end view of the biosensor cartridge as viewed from the rear, and (D) is an end surface of the biosensor cartridge as viewed from the front. FIG. (A) is a side view of a chip body. (B) is a plan view of the chip body. (A) is a front view which shows the protrusion for holding | grip. (B) and (C) are end views showing gripping projections. FIG. 10 is a plan view showing a modification of the biosensor cartridge shown in FIG. 9. (A) is a top view which shows the chip body formed continuously. (B) is a front view of the base formed continuously. (C) is a front view showing a state in which a continuous base is attached to a continuous chip body and cut. It is sectional drawing which shows the modification of a biosensor cartridge. (A) is a perspective view of a conventional biosensor chip. (B) is an exploded perspective view of a biosensor chip.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10 Biosensor cartridge 11 Chip body 12 Locking notch 13 Protrusion notch 20 Grasping protrusion 20B Second base 21 Base 21a Tip surface 22 Puncture needle (puncture device)
23 Locking portion 23a Locking protrusion 25 Locking claw 31 Measuring device 32 Driving means 33 Protective cap 33a Slit

Claims (7)

  A biosensor cartridge having a chip body and a puncture device fixedly provided at the tip of the chip body, wherein the biosensor cartridge has gripping protrusions protruding in a direction penetrating both front and back surfaces of the chip body. A biosensor cartridge comprising:   The biosensor cartridge can be attached to a measuring device, and when the biosensor cartridge is attached to the measuring device having a protective cap at the tip, the gripping protrusion is inserted from the slit provided in the protective cap. The biosensor cartridge according to claim 1, wherein the biosensor cartridge is provided so as to protrude outside the protective cap.   The gripping protrusion is provided on a base that abuts on the chip body surface, and the base has a locking portion that locks a locking notch provided by cutting out the chip body. The biosensor cartridge according to claim 1 or 2. The locking portion includes a locking protrusion that penetrates the locking notch from the base that is in contact with one surface of the chip body, and a second that fits the locking protrusion on the other surface of the chip body. Consists of a base of
4. The biosensor cartridge according to claim 1, wherein the gripping protrusion protrudes from the base and the second base. 5. The locking notch is provided at an outer edge along the longitudinal direction of the chip body,
The locking portion has a plurality of locking claws provided to protrude from the outer edge portion of the lower surface of the base,
The gripping protrusion is provided so as to protrude from both upper and lower surfaces of the base, and the gripping protrusion provided on the lower surface of the base penetrates the protrusion notch provided in the center of the chip body and The biosensor cartridge according to any one of claims 1 to 3, wherein the biosensor cartridge is provided so as to protrude to the opposite side. The locking portion has a plurality of locking claws provided protruding from the lower surface of the base,
The gripping protrusion is provided so as to protrude from both upper and lower surfaces of the base, and the gripping protrusion provided on the lower surface of the base passes through the protrusion notch provided on the chip body and is opposite to the base. The biosensor cartridge according to any one of claims 1 to 3, wherein the biosensor cartridge is provided so as to project from the cartridge. A biosensor cartridge manufacturing method for manufacturing the biosensor cartridge according to any one of claims 1 to 6,
A plurality of the chip bodies are integrally formed continuously, and a plurality of the bases having the gripping protrusions are continuously formed integrally. After the bases are locked to the chip body, the chips are formed. A biosensor cartridge manufacturing method, wherein a main body and the base are separated together to manufacture a biosensor cartridge.

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