JP2008076243A5 - - Google Patents

Download PDF

Info

Publication number
JP2008076243A5
JP2008076243A5 JP2006256113A JP2006256113A JP2008076243A5 JP 2008076243 A5 JP2008076243 A5 JP 2008076243A5 JP 2006256113 A JP2006256113 A JP 2006256113A JP 2006256113 A JP2006256113 A JP 2006256113A JP 2008076243 A5 JP2008076243 A5 JP 2008076243A5
Authority
JP
Japan
Prior art keywords
analysis
detection time
sample
component
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006256113A
Other languages
Japanese (ja)
Other versions
JP2008076243A (en
JP4861107B2 (en
Filing date
Publication date
Application filed filed Critical
Priority to JP2006256113A priority Critical patent/JP4861107B2/en
Priority claimed from JP2006256113A external-priority patent/JP4861107B2/en
Publication of JP2008076243A publication Critical patent/JP2008076243A/en
Publication of JP2008076243A5 publication Critical patent/JP2008076243A5/ja
Application granted granted Critical
Publication of JP4861107B2 publication Critical patent/JP4861107B2/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Claims (8)

分析試料を注入する試料注入部と、
前記試料注入部により注入された前記分析試料を成分毎に分離する分離カラムと、
前記分離カラムにより分離された前記分析試料の成分を検出する検出器と、
前記分析試料の数を入力する入力部と、
前記入力部で指定された分析試料数の分析を行うように前記試料注入部、前記分離カラム、前記検出器、および入力部等の各ユニットを制御する制御部と、
分析により得られるクロマトグラムを記録する記録部とを備えた液体クロマトグラフを含むクロマトグラフ装置において、
前記成分の検知開始から終了までの検出時間範囲を記憶する記憶手段と、
前記記憶手段に記憶された検出時間範囲を基に複数の前記分析試料を前記試料注入部に注入する注入間隔を算出する処理手段と、
前記注入間隔を適用して前記複数の分析試料の分析が行われるように各ユニットを制御する制御手段を有することを特徴とするクロマトグラフ装置。
A sample injection part for injecting an analysis sample;
A separation column for separating the analysis sample injected by the sample injection unit into components;
A detector for detecting a component of the analysis sample separated by the separation column;
An input unit for inputting the number of the analysis samples;
A control unit that controls each unit such as the sample injection unit, the separation column, the detector, and the input unit so as to perform analysis of the number of analysis samples specified by the input unit;
In a chromatograph apparatus including a liquid chromatograph provided with a recording unit for recording a chromatogram obtained by analysis,
Storage means for storing a detection time range from the detection start to the end of the component;
Processing means for calculating an injection interval for injecting a plurality of the analysis samples into the sample injection unit based on the detection time range stored in the storage means;
A chromatographic apparatus comprising control means for controlling each unit so that the analysis of the plurality of analysis samples is performed by applying the injection interval.
請求項1記載のクロマトグラフ装置において、
前記検出器として質量分析計を用い、
前記質量分析計で分析検知された成分の質量電荷比と前記検出時間範囲とを前記記憶手段に記憶し、
前記処理手段は前記検出時間範囲のうち、最大の検出時間範囲幅以上の時間間隔を前記注入間隔とすることを特徴とするクロマトグラフ装置。
The chromatographic apparatus according to claim 1,
Using a mass spectrometer as the detector,
The mass-to-charge ratio of the component analyzed and detected by the mass spectrometer and the detection time range are stored in the storage means,
The said processing means makes the time interval more than the largest detection time range width | variety among the said detection time ranges as the said injection | pouring interval, The chromatograph apparatus characterized by the above-mentioned.
請求項2記載のクロマトグラフ装置において、
同じ分析試料中に含まれる質量電荷比が同一または所定近似値以内にある複数成分について、前記複数成分の検知時間範囲を全て包含する複数成分検出時間範囲を新たに設定する機能を有することを特徴とするクロマトグラフ装置。
The chromatographic apparatus according to claim 2, wherein
A function of newly setting a multi-component detection time range including all the detection time ranges of the multi-components for a plurality of components having the same mass-to-charge ratio contained in the same analysis sample or within a predetermined approximate value. A chromatographic apparatus.
請求項2記載のクロマトグラフ装置において、
前記分析試料に含まれる検出対象成分の中からユーザが選択する任意の複数成分に跨がるユーザ選択複数成分検出時間範囲を新たに設定し、このユーザ選択複数成分検出時間範囲、および前記検出時間範囲から最も長い検出時間範囲を前記注入時間間隔とすることを特徴とするクロマトグラフ装置。
The chromatographic apparatus according to claim 2, wherein
A user-selected multi-component detection time range that extends over any of a plurality of components selected by the user from the detection target components included in the analysis sample is newly set, and the user-selected multi-component detection time range and the detection time A chromatograph apparatus characterized in that a longest detection time range from the range is the injection time interval.
請求項2記載のクロマトグラフ装置において、
前記分析試料の注入時刻と、前記分析試料に含まれる検出対象成分の質量電荷比と、前記検出対象成分の検出時間範囲を基に、前記検出対象成分が前記検出器に到達する検出予定時刻を算出する機能を備えることを特徴とするクロマトグラフ装置。
The chromatographic apparatus according to claim 2, wherein
Based on the injection time of the analysis sample, the mass-to-charge ratio of the detection target component contained in the analysis sample, and the detection time range of the detection target component, the detection scheduled time when the detection target component reaches the detector A chromatographic apparatus comprising a function for calculating.
請求項5記載のクロマトグラフ装置において、
前記検出予定時刻と、分析により得られる成分の検出時刻を基に、検出された検出成分を前記分析試料に帰属して記録する機能を備えることを特徴とするクロマトグラフ装置。
The chromatographic apparatus according to claim 5, wherein
A chromatograph apparatus comprising a function of recording a detected detected component belonging to the analysis sample based on the scheduled detection time and a detection time of a component obtained by analysis.
請求項1記載のクロマトグラフ装置において、
前記検出器としてDAD検出器を用い、
前記記憶手段は前記分析試料に含まれる成分の吸収波長と検出時間範囲とを各々記憶し、
前記処理手段は前記分析試料に含まれる成分の検出時間範囲のうち、最大の時間幅以上の時間間隔を前記注入間隔とすることを特徴とするクロマトグラフ装置。
The chromatographic apparatus according to claim 1,
Using a DAD detector as the detector,
The storage means stores an absorption wavelength and a detection time range of each component contained in the analysis sample,
The chromatographic apparatus characterized in that the processing means sets a time interval equal to or greater than a maximum time width in the detection time range of components contained in the analysis sample as the injection interval.
分析試料を注入する試料注入部と、
前記試料注入部により注入された前記分析試料を成分毎に分離する分離カラムと、
前記分離カラムにより分離された前記分析試料の成分を検出する検出器を備えた分析方法において、
前記分析試料の各成分検出の開始から終了までにかかる検出時間範囲を基に複数の前記分析試料を前記試料注入部に注入する注入間隔を算出することを特徴とする分析方法。
A sample injection part for injecting an analysis sample;
A separation column for separating the analysis sample injected by the sample injection unit into components;
In an analysis method comprising a detector for detecting a component of the analysis sample separated by the separation column,
An analysis method characterized in that an injection interval for injecting a plurality of the analysis samples into the sample injection section is calculated based on a detection time range required from the start to the end of detection of each component of the analysis sample.
JP2006256113A 2006-09-21 2006-09-21 Chromatograph apparatus and analysis method Expired - Fee Related JP4861107B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2006256113A JP4861107B2 (en) 2006-09-21 2006-09-21 Chromatograph apparatus and analysis method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006256113A JP4861107B2 (en) 2006-09-21 2006-09-21 Chromatograph apparatus and analysis method

Publications (3)

Publication Number Publication Date
JP2008076243A JP2008076243A (en) 2008-04-03
JP2008076243A5 true JP2008076243A5 (en) 2008-07-17
JP4861107B2 JP4861107B2 (en) 2012-01-25

Family

ID=39348467

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006256113A Expired - Fee Related JP4861107B2 (en) 2006-09-21 2006-09-21 Chromatograph apparatus and analysis method

Country Status (1)

Country Link
JP (1) JP4861107B2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4980740B2 (en) * 2007-01-31 2012-07-18 株式会社 資生堂 Two-dimensional liquid chromatography analysis method and sorting flow path switching unit
JP5445149B2 (en) * 2010-01-08 2014-03-19 株式会社島津製作所 ANALYZER CONTROL SYSTEM AND PROGRAM FOR THE SYSTEM
JP5545494B2 (en) * 2011-04-05 2014-07-09 横河電機株式会社 Chromatograph
US8669519B2 (en) * 2011-12-05 2014-03-11 Quest Diagnostics Investments, Inc. Methods for detecting reverse triiodothyronine by mass spectrometry
TWI613445B (en) * 2016-04-01 2018-02-01 行政院農業委員會農業藥物毒物試驗所 Method and system for inspecting pesticide residue in argicultural products using mass spectrometry imaging analysis
US11828737B2 (en) 2017-04-05 2023-11-28 Shimadzu Corporation Preparative liquid chromatograph
CN111398611A (en) * 2019-01-03 2020-07-10 深圳迈瑞生物医疗电子股份有限公司 Sample detection time estimation method and device, sample analyzer and storage medium
CN111289640B (en) * 2020-02-27 2022-12-13 南京凯通粮食生化研究设计有限公司 Liquid chromatography detection method for improving detection efficiency by advancing sample introduction
JP2022123952A (en) * 2021-02-15 2022-08-25 株式会社島津製作所 liquid chromatograph
CN115453030A (en) * 2022-09-28 2022-12-09 博莱克科技(武汉)有限公司 Method for improving gas chromatography detection efficiency

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3180391B2 (en) * 1991-12-09 2001-06-25 株式会社島津製作所 Liquid chromatograph
JP3700368B2 (en) * 1998-01-12 2005-09-28 株式会社島津製作所 Chromatographic data processor
JP3938086B2 (en) * 2003-04-04 2007-06-27 株式会社島津製作所 Chromatographic data processor

Similar Documents

Publication Publication Date Title
JP2008076243A5 (en)
JP4861107B2 (en) Chromatograph apparatus and analysis method
JP4985851B2 (en) Preparative liquid chromatograph
US7823439B2 (en) Method for identifying the composition of a sample
US10184925B2 (en) Preparative separation chromatograph system
JP6468967B2 (en) Preparative liquid chromatograph apparatus and preparative condition searching method
US20110306146A1 (en) Parallel Screening Supercritical Fluid Chromatography
JP6558032B2 (en) Preparative chromatograph
US10401334B2 (en) Control system and program for liquid chromatograph
JP5751380B2 (en) Multidimensional chromatograph
WO2015160587A1 (en) Online gas chromatograph operation with reduced usage of calibration gas
JP6801779B2 (en) Preparative liquid chromatograph
JP5134636B2 (en) High speed liquid chromatograph apparatus and liquid feeding method of high speed liquid chromatograph apparatus
CN102735765A (en) Chromatograph
Snow Split, splitless, and beyond—Getting the most from your inlet
WO2018167986A1 (en) Data processing device for chromatograph
JP4536570B2 (en) Liquid chromatograph analyzer
JP2005257575A (en) Chromatograph
Snow Split/Splitless Inlets in Gas Chromatography: What’s Up with All Those Different Glass Inlet Liners?
JP5195686B2 (en) Liquid chromatograph
JPWO2020105661A5 (en)
JP5076807B2 (en) Multi-dimensional gas chromatograph
JP7359838B2 (en) Method for adjusting the concentration of a sample gas in a gas mixture analyzed by a gas chromatograph assembly and the chromatograph assembly used therefor
US20160195500A1 (en) Chromatographic device and method
JP2016017941A5 (en)